Session Details

[3S15m]Metabolic control of disease metabolites and their medical applications

Wed. Mar 19, 2025 8:30 AM - 10:20 AM JST
Wed. Mar 19, 2025 11:30 PM - 1:20 AM UTC
Room 15
Oranizers :Motohiro Nishida (Department of Physiology, Graduate School of Pharmaceutical Sciences, Kyushu University) and Fanyan Wei (IDAC, Tohoku University)
Joint Session : JST
With drastic changes in our living environment due to emergence of new infectious diseases or digital transformations, diseases and disorders are becoming increasingly complex. In order to contribute to the early treatment of diseases, there is a demand for the development of high-resolution detection techniques and quantitative measurement techniques that lead to the discovery of novel disease-related factors, as well as technologies that dramatically increase their throughput and various information technologies. Additionally, it is necessary to develop and enhance a suite of technologies for analyzing and identifying target molecules for medical applications through the identification of metabolites, proteins, and metabolic pathways affected by known bioactive compounds. Against this backdrop, the Japan Science and Technology Agency (JST) launched the pioneering field of "Creation of Innovative Medical Foundation Technologies Based on Analysis of Metabolites in Diseases and Metabolic Control" (fiscal years 2013-2018). Research efforts have been directed towards the conceptual validation of human disease control based on target molecules within the body, which can serve as targets for medical applications, primarily led by young researchers. This symposium aims to introduce unique cutting-edge research technologies and achievements born from this field of research and to foster new organic collaborations.

[[OD]3S15m-1]Multi-omics analysis using Alzheimer's disease human plasma samples

Yoshiya Oda (The University of Tokyo, Graduate School of Medicine)
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[3S15m-2]Perspectives on the regulation of modified RNA Metabolite "Modified Nucleosides" and their medical applications

Akiko Ogawa1, Satoshi Watanabe2, Allen Yi-Lun Tsai3, Kimi Araki3, Shinichiro Sawa3, Kenji Inaba2, Fan-Yan Wei1 (1.Tohoku Univ., 2.Kyushu Univ., 3.Kumamoto Univ.)
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[3S15m-3]Improving systemic glucose metabolism disorders by the maintenance of mitochondrial quality

Yuri Kato1, Motohiro Nishida1,2 (1.Department of Physiology, Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, 2.NIPS)
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[[OD]3S15m-4]Development of single-molecule liquid biopsy platform for detection of pancreatic tumor form proteoform-level protein functional alterations

Toru Komatsu (Grad. Sch. Pharm. Sci., Univ. Tokyo)
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[[OD]3S15m-5]Tracing and the fate of oxygen metabolism

Yuki Sugiura (Kyoto University, Center for Cancer Immunotherapy and Immunobiology)
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