Presentation Information
[2P-61]A study on how backbone N-methylation patterns of Cyclosporin A affect its passive membrane permeability
*Motoki Sugano1, Takahiro Ono1, Takumi Ueda2,3, Koh Takeuchi3, Jumpei Morimoto1, Shinsuke Sando1 (1. Graduate School of Engineering, The university of Tokyo, 2. Graduate School of Pharmaceutical, Osaka university, 3. Graduate School of Pharmaceutical, The university of Tokyo)
Keywords:
Cyclic peptides,Passive membrane permeability,Cyclosporin A,N-methylated peptides,Structural analysis