The 18th Symposium on Biorelevant Chemistry
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Session Details

Poster Session : 2P-01～2P-109

ポスター発表

Fri. Sep 13, 2024 10:40 AM - 12:20 PM JST
Fri. Sep 13, 2024 1:40 AM - 3:20 AM UTC
Poster Session Hall(Multi-purpose Hall)

[2P-01]Development of highly sensitive monobodies targeting HOIP-PUB domain

*Kiyose Sakai1, Atsushi Manabe2, Keiichiro Kadoba2, Tomoshige Fujino1, Gousuke Hayashi1, Akio Morinobu2, Kazuhiro Iwai3, Hiroshi Murakami1 (1. Department of Biomolecular Engineering,Graduate School of Nagoya University, 2. Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, 3. Department of Molecular and Cellular Physiology Graduate School of Medicine Kyoto University)

[2P-02]Rational enzyme engineering using a machine learning model trained with protein structure data

*Satoshi Yuzawa1 (1. Tokyo University of Agriculture and Technology)

[2P-03]Automated Docking-Based Selection of Carboxylesterase for Deprotection of Novel Sialic Acid Analogues as Antiviral Prodrugs

*NIRANNJHEENI ALAGAPPAN1, CHRISTOPHER VAVRICKA1, KIYOTA HIROMASA 2 (1. Biotechnology and Life Science, Faculty of Engineering, Tokyo University of Agriculture and Technology, 2. Faculty of Environmental, Life, Natural Science and Technology, Okayama University)

[2P-04]PNA hybridization-assisted peptide ligation for chemical protein synthesis

*Sae Suzuki1, Shingo Mizushima1, Yukino Takeuchi1, Gosuke Hayashi1, Hiroshi Murakami1,2 (1. Nagoya University, 2. Institute of nano-life-systems, Nagoya Univ.)

[2P-05]Dimer construction and intracellular expression of hinge-loop mutated human cytochrome c

*Kotori Ohta1, Kodai Fujiwara1, Tsuyoshi Mashima1, Naoya Kobayashi1, Kenichi Kanai1, Takaaki Matsui1, Bessho Yasumasa1, Shun Hirota1 (1. Nara Institute of Science and Technology)

[2P-06]Development of Reversible Protein Labeling Probe with Red fluorescence

*Nana Otani1, Masafumi Minoshima1, Kazuya Kikuchi1,2 (1. Graduate School of Engineering, Osaka Univ, 2. Immunology Frontier Research Center, Osaka Univ)

[2P-07]Highly efficient Ser/Leu-swapped translation with natural/in vitro transcribed-hybrid tRNA set

*Taito Higashinagata1, Tomoshige Fujino1, Ryogo Sonoda1, Emi Mishiro2, Keiko Kano2, Hiroshi Murakami1,3 (1. Graduate School of Engineering, Nagoya University, 2. Institute of Transformative Bio-Molecules, Nagoya University, 3. Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University)

[2P-08]Development of photoresponsive ligands based on the structural information of the antagonist and muscarinic receptor complex

*Aika Mizuno1, Tomohiro Doura1, Shigeki Kiyonaka1 (1. Engineering, Nagoya University)

[2P-09]Photoactivation of Adenosine A2A receptor with photoresponsive ligands

*Harufumi Suzuki1, Yuya Matsuba1, Tomohiro Doura1, Shigeki Kiyonaka1 (1. Engineering, Nagoya University)

[2P-10]Synthesis of deuterated nucleosides using metal and enzyme catalysts

*Mayuri Koga1, Akihiko Hatano1 (1. Faculty of Materials Science and Engineering, Shibaura Institute of Technology)

[2P-11]Terminal-specific polymerization of fibrous Proteins for the creation of ultra-large artificial biomolecular assemblies

*Ayasa Nagatani1, Kosuke Minamihata1, Masahito Ishikawa2, Shogo Yoshimoto3, Katsutoshi Hori3, Noriho Kamiya1,4 (1. Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 2. Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology, 3. Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, 4. Devision of Biotechnology, Center for Future Chemistry, Kyushu University)

[2P-12]A method for proteomics analysis of DNA damage foci using split protein probes

*Kenji Yatsuzuka1, Kaiji Ito1, Airi Watanabe1, Risako Fukata1, Yuki Tashiro1, Hidenori Kaneoka2, Shigeki Kiyonaka1 (1. Graduate School of Engineering, Nagoya University, 2. Faculty of Engineering, Aichi Institute of Technology)

[2P-13]Development of fluorescent labeling ligand of AMPA receptor for rapid and reversible visualization

*Mayu Nakagawa1, Kyohei Soga1, Hansel Adriel2, Akihiro Shibata1, Takaaki Fujiwara2, Eriko Nango2,3, Shigeki Kiyonaka1 (1. Engineering, Nagoya University, 2. IMRAM, Tohoku University, 3. Riken, Spring-8)

[2P-14]Bioluminescence resonance energy transfer assay using MBD-fused luciferase and MBD-fused fluorescent protein for global DNA methylation level sensing

*Yuto Shoji1, Yuno Ikeda2, Rie Rin1, Masayoshi Tanaka3, Wataru Yoshida1,2 (1. Graduate School of Bionics, Tokyo University of Technology, 2. School of Bioscience and Biotechnology, Tokyo University of Technology, 3. Department of Chemical Science and Engineering, Tokyo Institute of Technology)

[2P-15]Detection of CpG methylation level using fluorescent modified methylated probe DNA with methyl-CpG binding domain-fused luciferase

*Takaaki Hayakawa1, Naoki Kuroda1, Takahiro Arakawa2, Jun Sumaoka2, Wataru Yoshida1 (1. Graduate School of Bionics, Tokyo University of Technology, 2. Graduate School of Sustainable Engineering, Tokyo University of Technology)

[2P-16]Visualization and analysis of DNA repair foci using a specific fluorescent protein probe

*Kaiji Ito1, Kenji Yatsuzuka1, Airi Watanabe1, Risako Fukata1, Yuki Tashiro1, Hidenori Kaneoka2, Shigeki Kiyonaka 1 (1. Engineering, Nagoya University, 2. Faculty of Engineering, Aichi Institute of Technology)

[2P-17]Development of a non-invasive in vivo chemogenetic method for elucidating the physiological function of metabotropic glutamate receptor subtype 1

*Takumi Kondo1, Tomohiro Doura1, Tomoteru Yamasaki2, Masayuki Fujinaga2, Ming-Rong Zhang2, Wataru Kakegawa3, Shigeki Kiyonaka1 (1. Graduate School of Engineering, Nagoya University, 2. National Institutes for Quantum Science and Technology, 3. Keio University School of Medicine)

[2P-18]Design and construction of polymerizable bacterionanofiber proteins

*Yuki Yokoe1, Rio Sugimoto1, Kosuke Minamihata2, Shogo Yoshimoto3, Katsutosi Hori3, Noriho Kamiya2,4, Masahito Ishikawa1 (1. Grad. Sch. Biosci., Nagahama Inst. Bio-Sci. Technol., 2. Grad. Sch. Eng., Kyushu Univ., 3. Grad. Sch. Eng., Nagoya Univ., 4. CFC, Kyushu Univ.)

[2P-19]Programmable cohesive liposomes for bottom-up creation of artificial cellular biofilms

*Rio Sugimoto1, Yuki Yokoe1, Shogo Yoshimoto2, Katsutoshi Hori2, Masahito Ishikawa1 (1. Grad. Sch. Biosci., Nagahama Inst. Bio-Sci. Technol., 2. Grad. Sch. Eng., Nagoya Univ.)

[2P-20]Serine-selective modification based on the catalytic ability of histidine

*Ayaka Masui1, Akitomo Kasahara2, Kenzo Yamatsugu2 (1. Faculty of Pharmaceutical Sciences, Chiba University, 2. Graduate School of Pharmaceutical Sciences, Chiba University)

[2P-21]Search of oligomerizable antibody light chains through 3D domain-swapping and effect of copper for the oligomerization

*Takahiro Sakai1, Shohei Yamaguchi1, Tsuyoshi Mashima1, Naoya Kobayashi1, Lian Duan2, Ryo Fujiki2, Kowit Hengphasatporn2, Yasuteru Shigeta2, Hideaki Ogata3, Emi Hifumi4, Taizo Uda5, Shun Hirota1 (1. Grad. Sch. Sci. Tech., NAIST, 2. Cent. Comp. Sci., Univ. Tsukuba, 3. Grad. Sch. Sci., Univ. Hyogo, 4. Inst. Res. Mgmt., Oita Univ, 5. Nano-tech Lab., ISIT)

[2P-22]Artificial metabolic pathways in DNA origami-based compartments

*Peng Lin1, Hui Yang 2, Eiji Nakata1, Takashi Morii1,3 (1. Institute of Advanced Energy, Kyoto University, 2. Graduate School of Energy Science, Kyoto University, 3. Department of Health and Nutrition, Kyoto Koka Women's University)

[2P-23]Towards construction of autonomously evolving artificial cells by self-membrane synthesis: Exploring lysophospholipid acyltransferases for membrane synthesis systems

*Kaito Seo1, Liam M Longo1, Tomoaki Matsuura1 (1. ELSI, Tokyo Tech)

[2P-24]High-throughput screening system for active mutants of crosslinking enzyme by combining hydrogel beads and cell-free protein synthesis

*Kensei Orita1, Taisei Koga1, Yui Okawa1, Tomoyuki Ito3, Kousuke Minamihata1, Mitsuo Umetsu3, Noriho Kamiya1,2 (1. Kyushu university faculty of engineering, 2. Kyushu University Centr of Future Chemistry, 3. Scool of Engeneering, Tohoku University)

[2P-25]Influence of the linker on biepitopic antigen-templated chemical reactions

*Hiroki Akiba1,2, Kentaro Nishiyama1, Haruhiko Kamada1,2, Hiroaki Ohno1,2 (1. Graduate School of Pharmaceutical Sciences, Kyoto University, 2. National Institutes of Biomedical Innovation, Health and Nutrition)

[2P-26]Exploration of thermostabilized human endothelin type b receptor (ETBR) mutants by ribosome display.

*Haruka Nishigaki1, Takeshi Murata2, Kenji Yasuda2, Keisuke Fukunaga3, Tomoaki Matsuura3 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. Graduate School of Science, Chiba University, 3. Earth Life Science Institute, Tokyo Institute of Technology)

[2P-27]Pseudo-glycosylation of Amyloid β by Laccase-catalyzed Tyrosine Click Reaction Alters Its Aggregation Property

Rin Higuchi1, Keita Nakane1, Tomoko Kikuchi1, Saori Yasuda1, Tatsuya Ikenoue2, Shinichi Sato1,3, *Shusuke Tomoshige1, Minoru Ishikawa1 (1. Graduate School of Life Sciences, Tohoku University, 2. Graduate School of Science, The University of Tokyo, 3. FRIS, Tohoku University)

[2P-28]Acceleration of oxidative protein folding by a polystyrene-based resin decorated with chalcogenide compounds

*Yuya Nishizawa1, Kenta Arai2,1 (1. Graduate School of Science, Tokai University , 2. Institute of Advanced Biosciences, Tokai University)

[2P-29]Analysis of Assembly Mechanisms of Multi-subunit Type CRISPR-Cas System and its Applications

*Wataru Nomura1,2, Haruki Kino1, Aozora Umemura1, Kiyomi Nigorikawa1,2 (1. Graduate School of Biomedical and Health Sciences, Hiroshima University, 2. School of Pharmaceutical Sciences, Hiroshima University)

[2P-30]Creation of a Basis Library for the Biosynthesis of 6-chloroindole-3-acetic acid Using Mutants of PLP-oxidase

*Noriyuki Shioura1, Satoshi Yuzawa1, Christopher Jhon VAVRICKA1 (1. Tokyo University of Agriculture and Technology)

[2P-31]Screening of ascorbic acid-dependent inhibitors of RNA demethylase, FTO

Kamui Tanaka1, Shiori Nishioka2, Akihiro Tai3, Shiroh Futaki1, *Miki Imanishi Imanishi1 (1. Institute for Chemical Research, Kyoto University, 2. Graduate School of Sciences and Technology for Innovation, Tokushima University, 3. Graduate School of Technology, Industrial and Social Sciences, Tokushima University)

[2P-32]Engineering of the active site of chitosanase hydrolyzing hetero β-1,4-glycosidic linkage between GlcN and GlcNAc

*Mariko Kojima1, Mehdi Davari2, Akira Onoda1 (1. Hokkaido University, 2. Leibniz Institute of Plant Biochemistry)

[2P-33]Construction of auto-fluorescent protein-based biosensor visualizing zinc finger structure of transcription factor Sp1

*Shunsuke Tajima1, Eiji Nakata2, Takashi Morii2,3, Jun Kuwahara1 (1. Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, 2. Inst. Adv. Energy, Kyoto Univ., 3. Dept. health and Nutr., Kyoto Koka Women's Univ.)

[2P-34]Construction of an expression system for a novel PQQ-dependent alcohol dehydrogenase and evaluation of the activity of the obtained enzyme

*Akiha Ichikawa1 (1. Dept. Biotechnol. Life Sci., Tokyo Univ. Agric. Technol)

[2P-35]Development of ONOO--responsive protein labeling reagents for conditional proteomics

*Hiroaki Uno1, Hao Zhu1, Kyoichi Matsuba1, Itaru Hamachi1,2 (1. Graduate School of Engineering, Kyoto University, 2. JST ERATO)

[2P-36]In-situ construction of protein assembly to visualize intracellular target by EM imaging

*Ippei Takashima1, Hiroto Takahashi1, Chieko Saito2, Masahide Kikkawa2, Shin Mizukami1 (1. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2. Graduate School of Medicine, Tokyo University)

[2P-37]Characterization of cobalt-substituted cytochrome P450 produced using ferrochelatase co-expression system.

*Mahiro Nakazawa1, Eri Akagawa1, Maki Sawada1, Kota Takeda2, Satoshi Fujii3, Masafumi Yohda1, Nobuhumi Nakamura1 (1. Depart. of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2. National Insti. of Advanced Industrial Sci. and Technol. (AIST), 3. Depart. of Nanobiochem., FIRST (Faculty of Frontiers of Innovative Research in Sci. and Technol.), Konan University)

[2P-38]Optimization of synthetic ligand-induced protein translocation (SLIPT) system for fission yeast and chemogenetic control of endogenous signaling proteins.

*Akinobu Nakamura1,2, Yuhei Goto2,3, Hironori Sugiyama2,4, Shinya Tsukiji5, Kazuhiro Aoki2,3 (1. Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2. Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences (NINS), 3. Graduate School of Biostudies, Kyoto University, 4. Graduate School of Engineering, the University of Tokyo, 5. Graduate School of Engineering, Nagoya Institute of Technology)

[2P-39]Accelerated photo-cross-linking to purine bases in duplex using reversible DNA photocross-linking

*Akira Fujioka1, Rei Hirahara1, Junling Mo1, Kenzo Fujimoto1 (1. Biofunctional Medical Engineering Research Area, Japan Advanced Institute of Science and Technology)

[2P-40]Development of Dehydroevodiamine derivatives as G-quadruplex ligand

*Yue Ma1, Tomoki Oyamada2, Hiroyuki Kagechika2 (1. Research Core Center, Tokyo Medical and Dental University, 2. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University)

[2P-41]Importance of Chiral Nucleic Acid on Chemical Template-Directed Synthesis

*Hikari Okita1, Keiji Murayama1, Hiroyuki Asanuma1 (1. Graduate School of Engineering, Nagoya University)

[2P-42]Installation of phosphorodiamidate bonds into novel cyclic artificial nucleic acids based on acyclic nucleic acids.

*Mika Shibata1, Keiji Murayama1, Hiroyuki Asanuma1 (1. Nagoya University)

[2P-43]Analysis of the non-enzymatic ligation of L-aTNA with histidine-Cd2+ complexes

*Hiroma Bessho1, Keiji Murayama1, Hiroyuki Asanuma1 (1. Graduate School of Engineering, Nagoya Univ.)

[2P-44]Creation of artificial viral capsid encapsulated quadruplex DNA

*Motono Ishii1, Hiroshi Inaba1, Tamaki Endoh2, Hisae Karimata Tateishi2, Naoki Sugimoto2, Kazunori Matsuura1 (1. Graduate School of Engineering, Tottori University, 2. The Frontier Institute for Biomolecular Engineering Research, Konan University)

[2P-45]Synthesis of photo-responsive artificial nucleic acids with phenylazothiazole groups and gene regulation.

*Kouki Tamura1, Tatsuya Nishihara1, Kazuhito Tanabe1 (1. Department of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin University)

[2P-46]Photosensitizer-modified plasmid DNA for elucidation of repair mechanisms of oxidative DNA damage

*Masashi Ozawa1, Takashi Kanamori1, Yoshitaka Kawasoe2, Yaoyao Du1, Nanai Yoshida1, Hideya Yuasa1 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. Faculty of Science, Kyushu University)

[2P-47]Photochemical invasion of long DNA duplex using artificial nucleic acid probes for genome manipulation

*ZUMILA HAILILI1, Fujimoto Kenzo1 (1. Biofunctional Medical Engineering Research Area, Japan Advanced Institute of Science and Technology)

[2P-48]Development of Pseudo-Translation Reactions for Artificial Nucleic Acids Based on Non-Enzymatic Chain Elongation Reactions

*Yuki Hotta1, Hikari Okita1, Keiji Murayama1, Hiroyuki Asanuma1 (1. Graduate School of Engineering, Nagoya University)

[2P-49]Theoretical study on an enzymatic reaction of the hammerhead ribozyme

*Ayaka Matsuyama1, Masahiko Taguchi2, Shigehiko Hayashi1 (1. Graduate School of Science, Kyoto University, 2. IMRAM, Tohoku University)

[2P-50]Effects of linker arm structures on the efficiency of DNA polymerase reaction

*Yuka Kataoka1, Erika Nagatani1, Hidekazu Hoshino2, Yuuya Kasahara2,3, Satoshi Obika3,4, Masayasu Kuwahara1 (1. Graduate School of Integrated Basic Science, Nihon University, 2. National Institutes of Biomedical Innovation, Health and Nutrition, 3. Graduate School of Pharmaceutical Sciences, Osaka University, 4. Institute for Open and Transdisciplinary Research Initiatives, Osaka University)

[2P-51]Development of Photo-Reactive Peptide Nucleic Acids for Novel Photo Genome Editing Tools

*Juki Nakao1, Yu Mikame1, Yusuke Matsuzaki1, Jun.A Komano2, Atsushi Shibata3, Tsuyoshi Yamamoto1, Chikara Dohno4, Takehiko Wada5, Asako Yamayoshi1,6 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 3. Faculty of Pharmacy, Keio University, 4. SANKEN, Osaka University, 5. IMRAM, Tohoku University, 6. Department of Life Science and Technology, Tokyo Institute of Technology)

[2P-52]Screening of G-quadruplex forming sequences under molecular crowding environment

*Tamaki Endoh1,2, Shujiro Okuda3, Yiwei Ling3, Hisae Tateishi1,2, Naoki Sugimoto2 (1. FIRST, Konan University, 2. FIBER, Konan University, 3. School of Medicine, Niigata University)

[2P-53]Accumulation of nitrobenzyl group-tethered oligodeoxynucleotides in hypoxic cells

*Airi Kanayama1, Daigo Maehara1, Tatsuya Nishihara1, Kazuhito Tanabe1 (1. Graduate school of Science and Engineering, Aoyama Gakuin University)

[2P-54]Effect of DNA topology on liquid-liquid phase separation

*Ryusei Senda1, Nonoka Tadachi2, Ryotaro Bunya2, Ryu Tashiro3, Takanori Oyoshi1,2,4,5 (1. Graduate School of Integrated Science and Technology, Shizuoka Univercity, 2. Faculty of Science, Shizuoka Univercity, 3. Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 4. Graduate School of Science and Technology, Shizuoka Univercity, 5. Research Institute of Green Science and Technology, Shizuoka Univercity)

[2P-55]Preparation of Long-Chain Polynucleotides Using Terminal Deoxynucleotidyl Transferase and Their Biochemical Applications

*Akiho Kawamoto1, Mitsunobu Nakamura1, Tadao Takada1 (1. Graduate School of Engineering, University of Hyogo)

[2P-56]In droplet evolution of an RNA aptamer lightning-up a GFP-type fluorophore for its structural analysis and functional improvement

*Shino Aburaya1 (1. Graduate School of Pharma-Medical Science, University of Toyama)

[2P-57]Development of photo-cross-linking oligonucleotides to inhibit telomerase activity

*Risa Nishikawa1, Kentaro Kbata1, Kazuki Matsubara1, Kazuya Matsuo1, Tomonori Waku1, Akio Kobori1 (1. Graduate School of Science and Technology, Kyoto Institute of Technology)

[2P-58]Synthesis and applications of DNA scaffolded sensor to detect wide-range pH and cathepsin activity

*Mashal Asif1, Eiji Nakata1,2, Peng Lin1,2, Morii Takashi3 (1. Graduate school of Energy Science, Kyoto University, 2. Institute of Advanced Energy, Kyoto University, 3. Faculty of Health Science, Kyoto Koka Women's University, Japan)

[2P-59]Immunostimulatory activity of CpG oligodeoxynucleotides forming parallel-type guanine quadruplex structure

*Tomohiko Yamazaki1,2, Soumitra PATHAK1,2, Atsuya MOMOTAKE3, Kazunori IKEBUKURO4 (1. Research Center for Macromolecules and Biomaterials, National Institute for Materials Science, 2. Graduate School of Life Science, Hokkaido University, 3. Deptartment of Cehmistry, University of Tsukuba., 4. Graduate School of Technology, Tokyo University of Agriculture and Technology)

[2P-60]Regulation of target gene expression levels using next-generation nucleic acid medicine.

*Ayu Matsumoto1, Yousuke Katsuda1,2, Tomoki Kida1, Shin-ichi Sato1,2, Yusuke Kitamura1, Toshihiro Ihara1 (1. Faculty of Advance Science and Technology, Kumamoto University, 2. StapleBio Inc.)

[2P-61]A study on how backbone N-methylation patterns of Cyclosporin A affect its passive membrane permeability

*Motoki Sugano1, Takahiro Ono1, Takumi Ueda2,3, Koh Takeuchi3, Jumpei Morimoto1, Shinsuke Sando1 (1. Graduate School of Engineering, The university of Tokyo, 2. Graduate School of Pharmaceutical, Osaka university, 3. Graduate School of Pharmaceutical, The university of Tokyo)

[2P-62]Cyclic peptides based on RGG sequences and their structures and bindings to G4 DNA/RNA

*Tomoya Yamaguchi1, Kazuhisa Fujimoto1, Akira Nagatoishi2, Kouhei Tsumoto2, Tomoki Sakamoto3, Yudai Yamaoki3, Takashi Nagata3, Masato Katahira3, Natsuki Shibata4, Takanori Oyoshi4,5,6 (1. Faculty of Life Science, Kyushu Sangyo University, 2. School of Engineering, The University of Tokyo, 3. Institute of Advanced Energy, Kyoto University, 4. Graduate School of Integrated Science and Technology, Shizuoka University, 5. Graduate School of Science and Technology, Shizuoka University, 6. Research Institute of Green Science and Technology, Shizuoka University)

[2P-63]Analysis of intracellular behavior of peptide heterodimers labeled with FRET probes

*Karen Tanaka1, Masayuki Yamasaki2, Kin-ya Tomizaki1 (1. Faculty of Advanced Science and Technology, Ryukoku University, 2. Faculty of Agriculture, Ryokoku University)

[2P-64]Construction of a hydrogel containing an iron-binding trimeric peptide as a cross-linking unit

*Ayane Sakamoto1, Yuri Hidaka1, Takumi Ikeda1, Koji Oohora1, Takashi Hayashi1 (1. Graduate School of Engineering, Osaka University)

[2P-65]Synthesis and properties of collagen model peptides incorporating N-terminal His-tag

*Raraho Kanda1, Kin-ya Tomizaki1 (1. Ryukoku University)

[2P-66]Development of artificial hydrolases with cyclic peptide structure containing catalytic triad

*Shuto Akiyama1, Akitomo Kasahara2, Kenzo Yamatsugu2 (1. Faculty of Pharmaceutical Sciences, Chiba University, 2. Graduate School of Pharmaceutical Sciences, Chiba University)

[2P-67]Control of microtubule structures by azobenzene-incorporated cyclic Tau-derived peptides

*Mahoko Tateishi1, Hiroshi Inaba1, Akira Kakugo2, Kazunori Matsuura1 (1. Graduate School of Engineering, Tottori University, 2. Graduate School of Science, Kyoto University)

[2P-68]Microtubule stabilization by Tau-derived peptide dimers

*Yui Hayakawa1, Hiroshi Inaba1, Akira Kakugo2, Kazunori Matsuura1 (1. Graduate School of Engineering, Tottori University, 2. Graduate School of Science, Kyoto University)

[2P-69]Selection of SARS-CoV-2 spike protein-binding peptides in a levitated droplet

*Manaka Kawai1, Toshinori Sato1, Teruhiko Matsubara1, Nene Suzuki1 (1. Faculty of Science and Technology, Keio University)

[2P-70]Regulation of peptide structure and functions by removable peptide stapling

*Yusuke Toki1, Eichi Ozawa1, Gosuke Hayashi1, Hiroshi Murakami1,2 (1. Graduate School of Engineering, Nagoya University, 2. Institute of Nano-Life-Systems, Nagoya University)

[2P-71]Chloroplast-Targeting Antioxidant Peptides for Shielding Plants from Photo-oxidative Stress

*Takaaki Miyamoto1, Keiji Numata1,2,3 (1. Biomacromolecules Research Team, RIKEN, 2. Graduate School of Engineering, Kyoto University, 3. Institute for Advanced Biosciences, Keio University)

[2P-72]Amyloid polypeptide aggregation-regulating activity and neuronal protection of the polyphenolic compound Clovamide

*Hideyuki Shigemori1,2, Tatsuhiko Tsunoda3, Daigo Nomoto3, Nanoa Fujii3, Mitsushi J. Ikemoto4, Yusaku Miyamae1 (1. Institute of Life and Environmental Sciences, University of Tsukuba, 2. MiCS, University of Tsukuba, 3. Graduate School of Science and Technology, University of Tsukuba, 4. Institute of Health and Sport Sciences, University of Tsukuba)

[2P-73]Development of a novel DNA photo-crosslinking method capable of switching the crosslink position

*Ryu Takesada1, Toya Odai1, Junling Mo1, Kenzo Fujimoto1 (1. Japan Advanced Institute of Science and Technology (JAIST), Biofunctional Biomedical Engineering)

[2P-74]Modification of the hydrogen bond unit of peptide supramolecules for highly efficient intracellular uptake

*Yudai Fujiwara1, Rie Wakabayashi1, Noriho Kamiya1, Masahiro Goto1 (1. Graduate School of Engineering, Kyushu University)

[2P-75]Microscopic observation of calcium phosphate formation using peptide-encapsulated giant liposomes

*Shota Matsumoto1, Tomomi Koshiyama1 (1. Graduate School of Life Sciences, Ritsumeikan University)

[2P-76]Quantum chemical descriptors of tripeptides for their antioxidant activities

*Akimitsu Miyaji1 (1. School of Materials and Chemical Technology, Tokyo Institute of Technology)

[2P-77]Formation of cell-encapsulated hydrogels based on azide-modified hyaluronic acid and gelatine with water-soluble strain diyne

*Kiyoka Hosokawa1, Fumiya Sato1, Hernandez Paniagua Liliana Alejandra1, Natsuko Inagaki2, Taichi Taichi2, Daisuke Yoshino1, Masayuki Tera1 (1. Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2. Graduate School of Engineering, The University of Tokyo)

[2P-78]Cellular imaging using glucose-modified turn-on type fluorescent probes

*Yuki Sadai1, Takashi Kanamori1, Kenji Hida1, Chihiro Nogi1, Shun-ichiro Ogura1, Hideya Yuasa1 (1. School of Life Science and Technology, Tokyo Institute of Technology)

[2P-79]Investigation of enzyme-reactive peptide assemblies for stabilizing Oil-in-Water emulsion and vaccine applications

*Ayato Higuchi1, Rie Wakabayashi1, Masahiro Goto1,2, Noriho Kamiya1,2 (1. Graduate School of Engineering, Kyushu University, 2. Center for Future Chemistry, Kyushu University)

[2P-80]Deep Cancer Cell Spheroids Delivery of Antisense Oligonucleotide by Peptide Amphiphiles

*Ingram Tan1, Rie Wakabayashi1, Noriho Kamiya1,2, Masahiro Goto1,2 (1. Faculty of Engineering, Kyushu Univeristy, 2. Center for Future Chemistry, Kyushu University)

[2P-81]Evaluation of anticancer activity of drug-encapsulated DNA Origami dendrimer for application of DNA Origami method to DDS

*Koichi Tanimoto1, Yuki Minamide1, Maria Hashimoto1, Haruki Tanaka1, Yuki Mano1, Akinori Kuzuya1 (1. Department of Chemistry and Materials Engineering, Kansai University)

[2P-82]Isolation of a formaldehyde-resistant Pseudomonas sp. and evaluation of its formaldehyde dismutase activity

*Koki Toguchi1, Maho Kobayashi1, Atsuya Seki1, Minato Kodera1, Norihiro Kato1, Eri Nasuno1 (1. Integrated Science of Engineering and Agriculture, Regional Development Studies, Utsunomiya University)

[2P-83]Synthesis and evaluation of membrane-localizable gefitinib ligands targeting the epidermal growth factor receptor

*Keishi Mitamura1, Keita Tsutsui1, Masaru Yoshikawa1, Shinya Tsukiji1 (1. Graduate School of Engineering, Nagoya Institute of Technology)

[2P-84]Measurement of physical properties of gelatin/calcium alginate mixed gel and evaluation of cell adhesion

*koki Nishi1, Hideki Mori1, Masayuki Hara1 (1. Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University)

[2P-85]Design and Synthesis of Gene-Directed Caged Anisomycin with Senescent Cell Selectivity

*Rintaro Asakura1, Toshiaki Furuta1 (1. Faculty of Science, Toho University)

[2P-86]Design and synthesis of clickable caged compounds for cell-type selective targeting

*Takehide Nakai1, toshiaki Furuta1, Tsukuru Sato1 (1. Faculty of Science, Toho University)

[2P-87]Development of pterin-type fluorescent off/on probes by aggregation/dissociation

*Saki Nakai1, Yasushi Kawai1 (1. Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology)

[2P-88]Development of the polyrotaxane accumulated 1-deoxynojirimaycin to control the activity of a-glucosidase such as membrane enzyme

*yuta tenma1, akihiko hatano2 (1. Faculty of Applied Chemistry ,Shibaura Institute of Technology, 2. Faculty of Materials Science and Engineering)

[2P-89]Efficient Preparation of Fluorescence-Labeled Antibodies Using Specific Dye Uptake of Cyclodextrins

*Hiroyasu Yamaguchi1,2, Yuma Iwai1 (1. Graduate School of Science, Osaka University, 2. Forefront Research Center, Graduate School of Science, Osaka University)

[2P-90]Inhibitory effect of quorum sensing by trapping intercellular signal in Bacillus subtilis

*Natsume Akatsuka1, Narumi Ushijima2, Eri Nasuno2, Norihiro Kato2 (1. School of Engineering, Utsunomiya University, 2. Graduate School of Regional Development and Creativity, Utsunomiya University)

[2P-91]Development of a chemogenetic method for orthogonal activation of serotonin 5-HT2A receptors in a cell-type specific manner using clinical drugs

*Hajime Inoue1, Tomohiro Doura1, Shigeki Kiyonaka1 (1. Faculty of Engineering, Nagoya University)

[2P-92]Development of a novel single fluorescent protein-based glucose biosensor.

*Kenwa Tamagawa1, Saaya Hario1, Takuya Terai1, Robert E. Campbell1 (1. Chemistry Department, School of Science, the University of Tokyo)

[2P-93]The control of hydroxy compounds on the excited-state intermolecular proton transfer reaction

*Leyun Huang1, Yoshinobu Nishimura1 (1. University of Tsukuba)

[2P-94]An efficient affinity maturation method for antibody-like proteins by using CRISPR/dCas9 system

*MingYao Yan1, Ryusei Matsuo 2, Tomoshige FUJINO1, Gosuke HAYASHI1, Hiroshi MURAKAMI1,2 (1. Graduate School of Engineering, Nagoya University, 2. Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University)

[2P-95]Rapid HPLC electrochemical detection of labelled leucine and isoleucine

*Kenji Yokoyama1, Fumika Niwa1, Akuri Uehara1, Eito Kamimura1 (1. School of Bioscience and Biotechnology, Tokyo University of Technology)

[2P-96]Exploration of disease-specific enzyme activity using dipeptide library and its application to hyperpolarized molecular imaging

*Kei Arimura1, Abdelazim Elsayed Elhelaly2, Yuki Aketa1, Fuminori Hyodo2, Masayuki Matsuo2, Tsuyoshi Osawa1, Toru Komatsu3, Yasuteru Urano3,4, Yutaro Saito1, Shinsuke Sando1 (1. Graduate School of Engineering, Tokyo University, 2. School of Medicine, Gifu University, 3. Graduate School of Pharmaceutical Sciences, Tokyo University, 4. Graduate School of Medicine, Tokyo University)

[2P-97]Detection of SARS-CoV-2 using silica microparticle modified with peptides obtained by phage display selection

*Wakaba Morimura1, Manaka Kawai1, Nene Suzuki1, Toshinori Sato1, Teruhiko Matsubara1 (1. Faculty of Science and Technology, Keio University)

[2P-98]Development of tetravalent antibody-enzyme complexes by the fusion of antibody fragments and a tetrameric enzyme and the application to electrochemical immunosensing

Miho ODA1, *Qianming XU2, Kentaro HIRAKA3, Koji SODE4, Wakako TSUGAWA1, Kazunori IKEBUKURO1, Ryutaro ASANO1 (1. Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2. Department of Engineering, Tokyo University of Agriculture and Technology, 3. Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 4. Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University)

[2P-99]Sensitive detection of ciguatoxins using a neuroblastoma cell-based assay with voltage-gated potassium channel inhibitors

Toshiaki Yokozeki1,2, Madoka Kawabata1, Kazuhiro Fujita2, Masahiro Hirama1, *Takeshi Tsumuraya1 (1. Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 2. Department of Research and Development, Japan Food Research Laboratories)

[2P-100]Dual imaging of intracellular ATP and oxygen concentrations by measuring the emission lifetime of the ATP-sensing fluorescent protein QUEEN and platinum porphyrin

*Yuya Fujihara1, Shunsuke Odai1, Hidehiro Ito1, Toshiaki Kamachi1 (1. School of Life Science and Technology, Tokyo Institute of Technology)

[2P-101]Electrtochemical charactarization of gold nanomaterials and its application

*Shuto Osaki1,2, Eiichi Tamiya1,2 (1. Photo-Bio OIL, AIST, 2. Osaka Univ. SANKEN)

[2P-102]Label-free and minimally invasive simultaneous multi-point Raman spectroscopic analysis for cell and drug

*Kazuki Bando1,2, Hao-Xiao Li2, Menglu Li1,2, Katsumasa Fujita2,1 (1. AIST, 2. Osaka University)

[2P-103]Development of Multicolor Cell-ELISA for High-throughput Drug Screening by Human Orthogonal Enzyme

*Rui Hirakawa1, Ryosuke Kaneko2, Chuya Tateishi1, Akihiro Koga1, Takanatsu Hosokawa1, Ryosei Kaguma1, Kenta Tanito1, Kota Yamanaka1, Teruki Nii2, Akihiro Kishimura2,3, Takeshi Mori2, Yoshiki Katayama2,3 (1. Graduate School of System Life Sciences, Kyushu University, 2. Graduate School of Engineering, Kyushu University, 3. Center for Molecular Systems, Kyushu University)

[2P-104]Synthesis of novel DNA probes for the template-directed formation and release of ruthenium-Osmium complex

*Chihiro Sakai1, Ryo Narizumi1, Yusuke Kitamura1, Yousuke Katsuda1, Toshihiro Ihara1 (1. Faculty of Advanced Science and Technology, Kumamoto University)

[2P-105]Towards Automation of Experiments by SolutionDesigneRDB

*Yusuke Sakai1 (1. RIKEN BDR)
高校生参加企画

[2P-106]Research on Allelochemicals of Mushrooms

*Kana Matsumoto1, Taku Saegusa1,2 (1. Meikei High School, 2. Graduate School of Science and Tecnology, University of Tsukuba)
高校生参加企画

[2P-107]Study on the induction of narcolepsy symptoms during chocolate administration

*Kano Kobayashi1, Taku Saegusa1,2 (1. Meikei High School, 2. Graduate School of Science and Tecnology, University of Tsukuba)
高校生参加企画

[2P-108]To increase the success rate of cuttings ~The relationship between light wavelength and rooting~

*Yurino Fukuda1 (1. Ibaraki Pref. Namiki Secondary School)
高校生参加企画

[2P-109]Allelochemical and the cell cycle

*Yuta Shibuya1, Taichi Ishihara1 (1. Ibaraki Pref. Namiki Secondary School)
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