Session Details
[H931-4pm]17. Biofunctional Chemistry, Biotechnology
Thu. Mar 21, 2024 1:00 PM - 3:30 PM JST
Thu. Mar 21, 2024 4:00 AM - 6:30 AM UTC
Thu. Mar 21, 2024 4:00 AM - 6:30 AM UTC
H931(931, Bldg. 9 [3F])
Chair: Kunihiko Morihiro, Yukiko Kamiya
[H931-4pm-01]Developing the intracellular FRET imaging approach to elucidate the mechanism of anti-miRNA oligonucleotides
○Hongyu Zhu1, Yukiko Kamiya1,2, Hiroyuki Asanuma1 (1. Nagoya University , 2. Kobe Pharmaceutical University)
[H931-4pm-02]Development of Anti-miR-21 Oligonucleotide by Acyclic Nucleic Acids
○Yukiko Kamiya1,2, Fuminori Sato2, Hiroyuki Asanuma2 (1. Kobe Pharmaceutical University, 2. Nagoya University)
[H931-4pm-03]Reversible optical control of receptor activity by azobenzene base-containing DNA aptamer.
○Masahiro Wakano1, Keiji Murayama2, Ryosuke Ueki, Hiroyuki Asanuma2, Shinsuke Sando1 (1. Graduate School of Engineering, The University of Tokyo, 2. Graduate School of Engineering, Nagoya University)
Break
[H931-4pm-04]The influence of methylated DNA on DNA polymerase with strand displacement ability
○Mizuki Tomizawa1, Kiwako Watanabe1, Kaori Tsukakoshi1, Kazunori Ikebukuro1 (1. Tokyo University of Agriculture and Technology)
[H931-4pm-05]Vinyl-quinazolione derivatives-based RNA alkylation and the single-nucleotide resolution analysis by next generation sequencing
○Yutong Chen1,2, Kazumitsu Onizuka1,2, Kaoru Richard Komatsu3, Emi Miyashita3,4, Kaho Maeta3, Hirohide Saito4, Fumi Nagatsugi1,2 (1. IMRAM, Tohoku University, 2. Department of Chemistry, Graduate school of Science, Tohoku University, 3. xFOREST Therapeutics, 4. CiRA, Kyoto University)
[H931-4pm-06]Development of cancer-selective DNA aptamer using weakly acidic microenvironment-responsive artificial nucleobase
○Yuyuan Chen1, Kunihiko Morihiro1, Yui Nemoto1, Akito Ichimura1, Ryosuke Ueki1, Shinsuke Sando1, Akimitsu Okamoto1 (1. The University of Tokyo)
[H931-4pm-07]The Impact of Linker Structure and the Number of Fluorine-containing Functional Groups of Nucleic Acids on Cellular Uptake and siRNA Knockdown Efficacy
○Masako Takatsu1, Kunihiko Morihiro1, Yu Ota1,2, Kosuke Aikawa1, Takashi Okazoe1,2, Akimitsu Okamoto1 (1. The Univ. of Tokyo, 2. AGC Inc.)