Presentation Information

4:55 PM - 5:15 PM JST(7:55 AM - 8:15 AM UTC)English

[[A]D401-1vn-04]Improvement of siRNA target specificity by chemical modification to the 2' position of the sugar moiety of nucleic acids

○Kohei Nomura¹, Seongjin An², Hirotaka Murase¹, Kosuke Nakamoto¹, Yasuaki Kimura¹, Naoko Abe¹, Yoshiaki Kobayashi³, Kumiko Tei^2,3, Jiro Kondo⁴, Hiroshi Abe^1,5,6 (1. Graduate School of Science, Nagoya Univ., 2. Graduate School of Frontier Science, The Univ. of Tokyo, 3. Graduate School of Science, The Univ. of Tokyo, 4. Graduate School of Science, The University of Tokyo, 5. JST CREST, 6. iGCORE)

Keywords:

siRNA,off-target effect,chemically modified nucleic acid

Back to Session information