Presentation Information

10:40 AM - 11:00 AM JST(1:40 AM - 2:00 AM UTC)English

[[A]D401-4am-05]Synthesis and inhibitory effects on duplex formation of linear and cyclic prodrug-type antisense oligonucleotides activated by β-galactosidase

○Kento Miyaji¹, Kohji Seio¹ (1. Sch. Life Sci. Tech., Science Tokyo)

Prodrug-type antisense oligonucleotide,Self-immolative linker,CuAAC reaction,Inhibition of duplex formation,β-galactosidase