The 105th CSJ Annual Meeting
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Academic Program [Oral A]17. Biofunctional Chemistry, Biotechnology : Oral A

[[A]D401-3am]17. Biofunctional Chemistry, Biotechnology

Fri. Mar 28, 2025 9:00 AM - 11:40 AM JST
Fri. Mar 28, 2025 12:00 AM - 2:40 AM UTC
[A]D401(D401, Bldg. 4, Area 3 [4F])
9:00 AM - 9:10 AM JST(12:00 AM - 12:10 AM UTC)Japanese

[[A]D401-3am-01]Photoresponsive α-chloroaldehyde-conjugated oligonucleotides as telomerase inhibitors

Kentaro Kobata1, ○Risa Nishikawa1, Kazuya Matsuo1, Tomonori Waku1, Akio Kobori1 (1. Graduate School of Science and Technology, Kyoto Institute of Technology)
9:10 AM - 9:20 AM JST(12:10 AM - 12:20 AM UTC)Japanese

[[A]D401-3am-02]Synthesis and properties of oligonucleotides containing nucleosides with amino alcohols at the 4'-position of the sugar moiety

○yusei masuoka1, Sakurako Onishi2, Yoshihito Ueno1,2 (1. Graduate School of Natural Science and Technology, 2. The Univ. of Gifu)
9:20 AM - 9:30 AM JST(12:20 AM - 12:30 AM UTC)Japanese

[[A]D401-3am-03]Synthesis and properties of RNAs with spermine molecules at the 5' or 4' -C- position of a nucleoside sugar moiety

○souma suzuki1, Keisuke Koyasu1, Yoshihito Ueno1,2 (1. The Graduate School of Natural Science and Technology, Gifu University , 2. Faculty of Applied Biological Science, Gifu University)
9:30 AM - 9:40 AM JST(12:30 AM - 12:40 AM UTC)Japanese

[[A]D401-3am-04]Post-modification of nucleic acids with amino acids via a cyano group

○Takumi Yoshida1, Natsuhisa Oka1,2,3 (1. Grad. Sch. Nat. Sci. Tech., Gifu Univ., 2. iGCORE, Gifu Univ., 3. COMIT, Gifu Univ.)
9:40 AM - 9:50 AM JST(12:40 AM - 12:50 AM UTC)Japanese

[[A]D401-3am-05]Stereoselective synthesis of nucleotide analog prodrugs (ProTides) by an oxazaphospholidine method

○Monta Nakamura1, Kiyoshi Kakuta1, Kazuki Sato1, Takeshi Wada1 (1. Tokyo University of Science)
9:50 AM - 10:00 AM JST(12:50 AM - 1:00 AM UTC)Japanese

[[A]D401-3am-06]Stereocontrolled synthesis of dimethyamino phosphorochloridate monomers for the synthesis of stereopure PMOs

○Ryuichi Inutake1, Hironao Hasegawa2, Tsurusaki Taiki1, Sato Kazuki1, Wada Takeshi1 (1. Tokyo University of Science, 2. Nippon Shinyaku Co)
10:00 AM - 10:10 AM JST(1:00 AM - 1:10 AM UTC)Japanese

[[A]D401-3am-07]Development of single nucleotide polymorphism detection method based on the specific binding between mismatched base pair and metal ion and the G-triplex formation

○Sora Sugao1, Akira Ono2, Hidetaka Torigoe1 (1. Tokyo University of Science, 2. Kanagawa University)
10:10 AM - 10:20 AM JST(1:10 AM - 1:20 AM UTC)Japanese

[[A]D401-3am-08]Study on novel sequences to form quadruplex nucleic acids in Dengue virus RNA genome

○Hikaru Ishii1, Tomohiro Ishikawa2, Shigeru Shimamoto3, Hidetaka Torigoe1 (1. Tokyo University of Science, 2. Dokkyo Medical University School of Medicine, 3. Kindai University)
10:20 AM - 10:30 AM JST(1:20 AM - 1:30 AM UTC)

Break

10:30 AM - 10:40 AM JST(1:30 AM - 1:40 AM UTC)Japanese

[[A]D401-3am-09]Dynamic observation of G-quadruplex using a light-up probe with a tri-oxazole scaffold

○Haruki Fujita1, Naruyuki Watatani1, Shogo Sasaki2, Yue Ma3, Sachiko Okabe4, Hiroyuki Seimiya4, Masayuki Tera1, Kazuo Nagasawa1 (1. Tokyo University of Agriculture and Technology, 2. Nara Women‘s University, 3. Institute of Science Tokyo, 4. Cancer Chemotherapy Center Japanese Foundation for Cancer Research)
10:40 AM - 10:50 AM JST(1:40 AM - 1:50 AM UTC)Japanese

[[A]D401-3am-10]Evaluation of the Effects of G4 Ligands on the Interaction between G-Quadruplexes and Their Binding Proteins

○Yuma Tanaya1, Hisao Masai2, Kazuo Nagasawa1, Masayuki Tera1 (1. Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2. Tokyo Metropolitan Institute of Medical Science)
10:50 AM - 11:00 AM JST(1:50 AM - 2:00 AM UTC)Japanese

[[A]D401-3am-11]Synthetic studies of the topological selective G4 ligands based on G4 templated synthesis

○Yuri Shimasawa1, Yue Ma2, Shogo Sasaki3, Masayuki Tera1, Kazuo Nagasawa1 (1. Tokyo University of Agriculture and Technology, 2. Institute of Science Tokyo, 3. Nara Women's University)
11:00 AM - 11:10 AM JST(2:00 AM - 2:10 AM UTC)Japanese

[[A]D401-3am-12]Structural analysis of mismatched DNA-ligand complex using heteronuclear NMR

○Shuhei Sakurabayashi1,2,3, Kyoko Furuita3, Takeshi Yamada2, Yohei Miyanoiri3, Kazuhiko Nakatani2, Chojiro Kojima1,3 (1. Yokohama National University, 2. SANKEN, Osaka University, 3. Institute for Protein Research, Osaka University)
11:10 AM - 11:20 AM JST(2:10 AM - 2:20 AM UTC)Japanese

[[A]D401-3am-13]NMR analysis of the complex of mismatched DNA and naphthyridine dimer with an asymmetric linker structure

○Yohei Shinno1, Shuhei Sakurabayashi1,2,3, Ayano Nakamachi2, Tomonori Shibata2, Kazuhiko Nakatani2, Chojiro Kojima1,3 (1. Yokohama National University, 2. SANKEN, Osaka University, 3. Institute for Protein Research, Osaka University)
11:20 AM - 11:30 AM JST(2:20 AM - 2:30 AM UTC)Japanese

[[A]D401-3am-14]Cellular uptake behavior of DOX-encapsulated DNA quadruplex-gel particles

○MARIA HASHIMOTO1, HARUKI TANAKA1, KOTA SAKAMOTO1, KOHEI TATSUMI1, YUICHI OHYA1, AKINORI KUZUYA1 (1. Dept. Chem. Mater. Eng., Kansai Univ.)
11:30 AM - 11:40 AM JST(2:30 AM - 2:40 AM UTC)English

[[A]D401-3am-15]Construction of an artificial CO2-fixing compartment using DNA nanostructure as a scaffold

○HUI YANG1, Peng Lin1, Eiji Nakata1, Takashi Morii1,2 (1. Kyoto Univ., 2. Kyoto Koka Women's Univ.)
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