Session Details
[[A]D401-4pm]17. Biofunctional Chemistry, Biotechnology
Sat. Mar 29, 2025 1:00 PM - 3:30 PM JST
Sat. Mar 29, 2025 4:00 AM - 6:30 AM UTC
Sat. Mar 29, 2025 4:00 AM - 6:30 AM UTC
[A]D401(D401, Bldg. 4, Area 3 [4F])
[[A]D401-4pm-01]Photoreaction of trioxsalens derivatives for DNA duplexes
○Kazuhisa Fujimoto1, Md Al Amin2, Takanori Oyoshi2 (1. Kyushu Sangyo University, 2. Shizuoka University)
[[A]D401-4pm-02]Enhancement of in vivo stability of Staple oligomers with artificial nucleic acids
○Ayu Matsumoto1, Yousuke Katsuda1,2, Tomoki Kida1, Shin-ichi Sato1,2, Yusuke Kitamura1, Toshihiro Ihara1 (1. Faculty of Advanced Science and Technology, Kumamoto University, 2. StapleBio Inc.)
[[A]D401-4pm-03]Inhibitory effect of RNA hacking technology with Staple oligomers on cardiac hypertrophy progression
○Miko Kato1, Yousuke Katsuda1,2, Tomoki Kida1, Masaki Hagihara3, Shin-ichi Sato1,2, Yusuke Kitamura1, Toshihiro Ihara1 (1. Faculty of Advanced Science and Technology, Kumamoto University, 2. StapleBio inc., 3. Faculty of Advance Science and Technology, Hirosaki University)
[[A]D401-4pm-04]Liquid-liquid phase separation of DNA G-quadruplex inhibited by 1,6-hexanediol
○Misaki Yoshikawa1, Mitsuki Tsuruta1, Nagisa Takamiya1, Keiko Kawauchi1, Daisuke Miyoshi1 (1. FIRST, Konan University)
[[A]D401-4pm-05]Enzymatic Synthesis of Oligonucleotide with 5′-C-Alkylthymidines by KOD DNA Polymerase Mutants
○Kenta Ishida1, Hidekazu Hoshino1, Takao Yamaguchi2, Satoshi Obika2,3, Yuuya Kasahara1,2 (1. NIBIOHN, 2. Grad. Sch. of Pharm. Sci., Osaka Univ., 3. OTRI, Osaka Univ.)
[[A]D401-4pm-06]Synthesis of Nucleotide-like Molecules from Nucleobases, Sugars, and Phosphates in Deep Marine Subsurface Supercritical CO2–Water Two-Phase Environment
○Kohei Morino1,2, Shotaro Tagawa1,2, Kosuke Fujishima1,3 (1. Earth-Life Science Institute, 2. Institute of Science Tokyo, 3. Keio University)
Break
[[A]D401-4pm-07]Development of a method for introducing damage using a photosensitizer to understand DNA repair mechanisms and evaluation of repair
○Takashi Kanamori1, Yoshitaka Kawasoe2, Masashi Ozawa1, Nanai Yoshida1, Yaoyao Du1, Yuma Yaginuma1, Hideya Yuasa1 (1. Science Tokyo, 2. Kyushu Univ.)
[[A]D401-4pm-08]Establishment of PNA/DNA complex formation in an intracellular environment
○Yasuna Nakazawa1, Jun Sumaoka1, Takeshi Matsui1 (1. Tokyo University of Technology graduate school)
[[A]D401-4pm-09]Exploration of Chemical Modifications of Nucleic Acids for Inducing Cell Function Regulation through Nucleic Acid Assembly Technology
○Tamako Aiba1 (1. The Univ. of Tokyo)
[[A]D401-4pm-10]Development of a nucleobase-recognition site-conjugated donor-acceptor complex catalyst for base selective trifluoromethylation.
○Haoran Zheng1, Harunobu Mitsunuma1, Motomu Kanai1 (1. The University of Tokyo)
[[A]D401-4pm-11]Nano-assembled structures and cellular delivery of fluorocarbon-DNA conjugate
○Minako Narita1, Ai Kohata1, Taiichi Kageyama1, Honoka Watanabe1, Kohsuke Aikawa1, Kunihiko Morihiro1, Akimitsu Okamoto1, Takashi Okazoe1,2, Daisuke Kawaguchi1 (1. The University of Tokyo, 2. AGC Inc.)
[[A]D401-4pm-12]Effect of DNA polymerase mutations in the fingers domain on incorporation of modified nucleotides
○Shun Tazawa1, Yuka Kataoka1, Hidekazu Hoshino2, Kenta Ishida2, Yuuya Kasahara2,3, Satoshi Obika3,4, Masayasu Kuwahara 1 (1. Grad. Sch. Integrated Basic Sci., Nihon Univ., 2. NIBIOHN, 3. Grad. Sch. Pharm. Sci., Osaka Univ., 4. OTRI, Osaka Univ.)
[[A]D401-4pm-13]Modification of the binding selectivity to G-quadruplexes by Thioflavin T oligomerization
○Tomoaki Nakamura1, Yuka Kataoka1, Masayasu Kuwahara1 (1. Grad. Sch. Integrated Basic Sci, Nihon Univ.)
[[A]D401-4pm-14]New Data Science in Nucleic Acids Chemistry (17): Development of a pseudo-cellular system with different molecular crowding environments
○Masako Takatsu1, Hisae Tateishi-Karimata1,2, Naoki Sugimoto1 (1. Konan University, FIBER, 2. Konan University, FIRST)