Presentation Information

[1T05-01]Structural basis for the mechanism of caffeine-induced recovery of loss-of-function RyR2 mutants.

Yuya Otori1, Raymond Burton-Smith2, Nagomi Kurebayashi3, Kazuyoshi Murata2, Hiroaki Kato1,4, Takashi Murayama3, Haruo Ogawa1 (1.Kyoto University Graduate School of Pharmaceutical Sciences, 2.The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 3.Juntendo University Graduate School of Medicine, 4.RIKEN SPring-8 Center)
キーテクノロジー:クライオ電子顕微鏡

Keywords:

2型リアノジン受容体、RyR2、Caffeine、イオンチャネル、機能欠失型変異体

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