Session Details
[1T05]Proteins 02
Wed. Nov 6, 2024 11:05 AM - 12:35 PM JST
Wed. Nov 6, 2024 2:05 AM - 3:35 AM UTC
Wed. Nov 6, 2024 2:05 AM - 3:35 AM UTC
Room5(G401)
Organizers: Shigeru Sugiyama(Kochi University), Yoshimasa Sagane (Tokyo University of Agriculture)
[1T05-01]Structural basis for the mechanism of caffeine-induced recovery of loss-of-function RyR2 mutants.
○Yuya Otori1, Raymond Burton-Smith2, Nagomi Kurebayashi3, Kazuyoshi Murata2, Hiroaki Kato1,4, Takashi Murayama3, Haruo Ogawa1 (1.Kyoto University Graduate School of Pharmaceutical Sciences, 2.The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 3.Juntendo University Graduate School of Medicine, 4.RIKEN SPring-8 Center)
キーテクノロジー:クライオ電子顕微鏡
[1T05-02]Structural insights into the enhancement of RyR2 activity by mutant calmodulin
○Ayuna Tsutsumi1, Yuya Otori1, Raymond Burton-Smith2, Nagomi Kurebayashi3, Kazuyoshi Murata2, Hiroaki Kato1,4, Takashi Murayama3, Haruo Ogawa1 (1.Kyoto University Graduate School of Pharmaceutical Sciences, 2.The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 3.Juntendo University Graduate School of Medicine, 4.RIKEN SPring-8 Center)
キーテクノロジー:クライオ電子顕微鏡
[1T05-03]Development of oxidoreductase-like allosteric catalyst triggered by Ca2+.
○Rumi Mikami1, Shingo Kanemura2, Masaki Okumura2, Kenta Arai1,3 (1.Department of Chemistry, School of Science, Tokai University, 2.Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, 3.Institute of Advanced Biosciences, Tokai University)
キーテクノロジー:生命有機化学
[1T05-04]The importance of site-specifically modified aspartyl residues on the eye lens molecular chaperone αB-Crystallin
○Daisuke Sasaki1, Ken Morishima2, Rintaro Inoue2, Masaaki Sugiyama2, Takumi Takata2 (1.Department of Chemistry, Graduate School of Science, Kyoto University, 2.Institute for Integrated Radiation and Nuclear Science, Kyoto University)
キーテクノロジー:アミノ酸置換
[1T05-05]Salt effect of α-synuclein NAC region in the amyloid fibril formations
○Ryota Imaura1, Koichi Matsuo1,2 (1.Graduate School of Advanced Science and Engineering, Hiroshima University, 2.Research Institute for Synchrotron Radiation Science, Hiroshima University)
キーテクノロジー:放射光真空紫外円二色性
[1T05-06]Molecular mechanisms of CRED2 contributing to the degradation of abnormal extracellular proteins
○Shumpei Kamano, Momoka Chiba, Akira Matsuura, Eisuke Itakura (Department of Biology, Graduate school of Science and Engineering Chiba University)
キーテクノロジー:細胞取り込みアッセイ
[1T05-07]Acquiring Hyper-Thermostability and Liquid-Crystal-Like Properties of Artificially Designed α-Helical Peptide Nanofibers
○Minami Kurokawa1, Atsuo Tamura2 (1.Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 2.Graduate School of Science, Department of Chemistry, Kobe University)
キーテクノロジー:Amidation of Carboxyl Group
[1T05-08]SKY plots allow for the discovery of allosteric drugs.
○Takuma Shiraki (BOST, Kindai Univeristy)
キーテクノロジー:アロステリック創薬
[1T05-09]Ca2+ dissociation from Pf-SCP, sarcoplasmic Ca-binding protein in Pinctada fucata, contributes to calcium transportation for shell mineralization
○Yuto Namikawa, Lingxiao Zhu, Michio Suzuki (Graduate School of Agricultural and Life Sciences, The University of Tokyo)
キーテクノロジー:multi-site calcium ion model