[1S09m] Pathophysiology Understood by the Intercellular Environment Regulated by Glycans and NOTCH Signaling | The 97th Annual Meeting of the Japanese Biochemical Society

The 97th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[1S09m]Pathophysiology Understood by the Intercellular Environment Regulated by Glycans and NOTCH Signaling

Wed. Nov 6, 2024 9:00 AM - 11:00 AM JST
Wed. Nov 6, 2024 12:00 AM - 2:00 AM UTC

Room9(G314)

Organizers：Tetsuya Okajima（Institute for Glyco-core Research, Nagoya University School of Medicine）, MOTOYUKI ITOH （Chiba University, Graduate School of Pharmaceutical Sciences）

9:00 AM - 9:05 AM JST(12:00 AM - 12:05 AM UTC)

[1S09m-00]Introduction

^○Tetsuya Okajima (Institute for Glyco-core Research, Nagoya University School of Medicine)

Comment()

9:05 AM - 9:25 AM JST(12:05 AM - 12:25 AM UTC)

[1S09m-01]Glycosylation of vascular endothelial amyloidβ precursor protein and the molecular pathogenesis of Alzheimer's disease

^○Shinobu Kitazume (Department of Clinical Laboratory Sciences, School of Health Sciences, Fukushima Medical University)

キーテクノロジー：糖鎖生物学

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9:25 AM - 9:44 AM JST(12:25 AM - 12:44 AM UTC)

[1S09m-02]Revisiting role of atypical O-glycan synthase based on tissue distribution

^○Yuji Kondo^1,2, Kaori Kawai^1,2, Noriko Toida¹, Katsuhiro Kato³, Tetsuya Okajima^1,2 (1.Nagoya Univ. Sch. Med., Biochemistry II, 2.Institute for Glyco-core Research, 3.Nagoya Univ. Sch. Med., Cardiology)

キーテクノロジー：初代培養

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9:44 AM - 10:03 AM JST(12:44 AM - 1:03 AM UTC)

[1S09m-03]Radical fringe impairs JAG1-dependent degradation of the NOTCH3 CADASIL mutant protein

Shodai Suzuki¹, Taiki Mashiko¹, Yohei Tsukamoto², Takemi Matsumoto¹, Hideyuki Takeuchi³, Tetsuya Okajima², ^○Motoyuki Itoh¹ (1.Graduate School of Pharmaceutical Sciences, Chiba University, 2.Graduate School of Medicine, Nagoya University, 3.School of Pharmaceutical Sciences, University of Shizuoka)

キーテクノロジー：LC-MS/MS, IHC, WB

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10:03 AM - 10:22 AM JST(1:03 AM - 1:22 AM UTC)

[1S09m-04]A role of the NOTCH signal in endothelial cell senescence

^○Koji Ikeda (Department of Cardiology, Kyoto Prefectural University of Medicine)

キーテクノロジー：血管内皮特異的老化マウス

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10:22 AM - 10:41 AM JST(1:22 AM - 1:41 AM UTC)

[1S09m-05]The role of Notch signaling in skeletal muscle regeneration and plasticity

^○Yusuke Ono^1,2 (1.Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, 2.Tokyo Metropolitan Institute for Geriatrics and Gerontology)

キーテクノロジー：シングルセル解析

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10:41 AM - 11:00 AM JST(1:41 AM - 2:00 AM UTC)

[1S09m-06]Quality control of Notch proteins by O-glucose glycosylation in the ER

^○Hideyuki Takeuchi (University of Shizuoka, School of Pharmaceutical Sciences, Department of Biochemistry)

キーテクノロジー：質量分析

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