Session Details
[2T04]Proteins 03
Thu. Nov 7, 2024 1:10 PM - 2:40 PM JST
Thu. Nov 7, 2024 4:10 AM - 5:40 AM UTC
Thu. Nov 7, 2024 4:10 AM - 5:40 AM UTC
Room4(G402)
Organizers: Hideki Nishitoh(University of Miyazaki), Kunio Nakatsukasa(Nagoya City University)
[2T04-01]Identification of cellular pathways regulating targeted protein degradation
○Yuki Mori1,2, Yoshino Akizuki1,2, Rikuto Honda1,2, Fumiaki Ohtake1,2 (1.Institute for Advanced Life Science, Hoshi University, 2.Graduate school of Pharmaceutical Science, Hoshi University)
キーテクノロジー:標的タンパク質分解
[2T04-02]Elucidation of the molecular mechanism by which SNIPER(ABL) induces both proteasomal and lysosomal degradation
○Sota Hashimoto1,2, Yoshinori Tsukumo3, Nobumichi Ohoka3, Akinori Endo4, Fumiaki Ohtake5, Yasushi Saeki6, Shigeo Murata1,2, Mikihiko Naito1,3 (1.Laboratory of Targeted Protein Degradation, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 3.National Institute of Health Sciences, 4.Tokyo Metropolitan Institute of Medical Science, 5.Hoshi University, 6.The Institute of Medical Science,The University of Tokyo)
キーテクノロジー:生化学
[2T04-03]Genetic analysis for homeostatic regulation of ribosomal protein levels in Drosophila
○Daiki Kitamura1,2, Kiichiro Taniguchi1, Mai Nakamura1, Tatsushi Igaki1 (1.Laboratory of Genetics, Graduate School of Biostudies, Kyoto University, 2.Department of Biological Sciences, Graduate School of Science, Osaka University)
キーテクノロジー:ショウジョウバエ遺伝学
[2T04-04]Disruption of Epidermal Proteostasis Governed by Secreted SERPINB7 Drives Skin Serpinopathy
○Takato Sugiyama1, Keitaro Umezawa2, Katsuhito Sasaki1, Risa Nobuta1, Chika Tsutsumi3, Yuri Miura2, Ryo Ushioda3,4, Toshifumi Nomura1 (1.Department of Dermatology, Institute of Medicine, University of Tsukuba., 2.Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology., 3.Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University., 4.Institute for Protein Dynamics, Kyoto Sangyo University.)
キーテクノロジー:ウエスタンブロット、質量分析
[2T04-05]A Quality Control System for Monitoring Protein Complex Integrity
○Takuya Tomita1,2, Masato Kanemaki3,4,5, Akinori Endo2, Hikaru Tsuchiya2, Keiji Tanaka2, Yasushi Saeki1,2 (1.The Institute of Medical Science, The University of Tokyo, 2.Tokyo Metropolitan Institute of Medical Science, 3.National Institute of Genetics, 4.Graduate Institute for Advanced Studies, 5.Department of Biological Science, The University of Tokyo)
キーテクノロジー:質量分析
[2T04-06]Elucidation of the Mechanism of Proteasome Localization Control by AKIRIN2 in Response to Nutritional Status
○Daiki Sawa, Sigeo Murata, Shoshiro Hirayama, Megan Lo (Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo)
キーテクノロジー:FACS、セルアナライザー
[2T04-07]A novel mechanism for lysosomal hydrolases trafficking via ubiquitination of Rab9a
○Jun Shirai, Toshiki Takahashi, Hiroyuki Kawahara (Cell. Biochem. Lab., Dept. of Biol. Sci., Tokyo Metropolitan Univ.)
キーテクノロジー:IP, シクロヘキシミドチェイス
[2T04-08]Function of the HECT E3 ligases UBE3C and HERC3 on the ER-associated degradation of CFTR.
○Yuka Kamada1, Hazuki Tateishi1, Uta Nakayamada1, Saori Katoh1, Hirotaka Takahashi2, Tsukasa Okiyoneda1 (1.Dept. of Biomed. Sci., Sch. of Biol. and Env. Sci., Kwansei Gakuin Univ., 2.Proteo-Science Center, Ehime Univ.)
キーテクノロジー:HiBiT ERAD assay
[2T04-09]Effect of the binding strength between substrate protein-bound GroEL and GroES on substrate folding activity
○Yaya Ishida, Nomura Minami, Koike-Takeshita Ayumi (Dept. Appl. Chemi. Biosci., Grad. Sch. Eng., Kanagawa Inst. of Tech.)
キーテクノロジー:ITC,SPR
[2T04-10]The intracellular dynamics of ubiquitin-like 3 visualized using inducible fluorescent timer expression system
○Yuka Terada1, Kumi Obara1, Yusuke Yoshioka2, Takahiro Ochiya2, Haruhiko Bito3, Kunihiro Tsuchida4, Hiroshi Ageta4, Natsumi Ageta-Ishihara1 (1.Department of Biomolecular Science, Faculty of Science, Toho University, 2.Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, 3.Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, 4.Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University)
キーテクノロジー:ライブイメージング