The 97th Annual Meeting of the Japanese Biochemical Society
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Session Details

Symposium

[3S14a]Cutting-edge research for development of diagnosis and therapeutics for Alzheimer's disease

Fri. Nov 8, 2024 1:35 PM - 3:35 PM JST
Fri. Nov 8, 2024 4:35 AM - 6:35 AM UTC
Room14(G319)
Organizers：Koichi Iijima（National Center for Geriatrics and Gerontology）, Motomasa Tanaka（RIKEN CBS）
1:35 PM - 2:05 PM JST(4:35 AM - 5:05 AM UTC)

[3S14a-01]Fluid biomarker phospho-tau217 appears in synapses around Aβ plaques prior to tau pathology in cerebral cortex of preclinical Alzheimer's disease

○Michiko Sekiya (National Center for Geriatrics and Gerontology)
キーテクノロジー：免疫組織染色
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2:05 PM - 2:35 PM JST(5:05 AM - 5:35 AM UTC)

[3S14a-02][11C]NCGG401 : Innovating Microglia PET imaging for Alzheimer's Disease Diagnosis

○Aya Ogata1,2 (1.Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science, 2.Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology)
キーテクノロジー：PETイメージング
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2:35 PM - 3:05 PM JST(5:35 AM - 6:05 AM UTC)

[3S14a-03]Tangle formation of Alzheimer's disease-fold Tau filaments by the negatively charged fuzzy coat

○Shingo Tamai1,2, Takashi Nomura1, Ryohei Kojima3, Ryo Fujioka4, John Burke1, Atsushi Yamagata5, Mikako Shirouzu5, Takeshi Fukuma3, Hiroki Sasaguri4, Motomasa Tanaka1,2 (1.Lab. for Protein Conformation Diseases, RIKEN CBS, 2.Graduate School of Medical & Dental Sciences, TMDU, 3.WPI-NanoLSI, Kanazawa Univ., 4.Dementia Pathophysiology Collaboration Unit, RIKEN CBS, 5.Lab. for Protein Functional and Structural Biology, RIKEN BDR)
キーテクノロジー：cryo-EM & FM-3D-AFM
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3:05 PM - 3:35 PM JST(6:05 AM - 6:35 AM UTC)

[3S14a-04]Investigation of Tau Aggregate Formation and Cellular Medicine Effects Using 3D Neuronal Cultures Derived from Human iPS Cells

○Sumihiro Maeda (Keio University)
キーテクノロジー：３次元培養法
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