[1S14m] Biochemical Approaches to Deciphering DNA Methylation

9:03 AM - 9:22 AM JST(12:03 AM - 12:22 AM UTC)

[1S14m-01] A dual-interface mechanism for DPPA3-mediated inhibition of UHRF1 via zinc-coordinated binding to the SRA domain

^○Shota Tanimoto¹, Christopher B. Mulholland³, Ayana Ota¹, Yoshie Chiba¹, Keita Sugimura¹, Kyohei Arita², Heinrich Leonhardt³, Atsuya Nishiyama¹, Makoto Nakanishi¹ (1.Division of Cancer Cell Biology, The Institute of Medical Science, The University of Tokyo, 2.Graduate School of Medical Life Science, Yokohama City University, 3.Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Human Biology and BioImaging, Ludwig-Maximilians-Universitat Munchen)

キーテクノロジー：ツメガエル卵抽出液

Keywords:

DNAメチル化,DPPA3,UHRF1,亜鉛イオン,タンパク質複合体

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