[2T20] Medical Inovation 01

10:50 AM - 11:00 AM JST(1:50 AM - 2:00 AM UTC)

[2T20-01] Dynamics-Based Characterization of the Binding Mechanism of Modified FcRn Ligands to IgG1

^○Jingwen Li¹, Hirofumi Kosuge¹, Satoru Nagatoishi², Linko Hirono³, Ryoko Otake³, Tatsuya Yumoto³, Yosuke Terao³, Teruhiko Ide³, Kouhei Tsumoto^1,2,4 (1.Department of Bioengineering, School of Engineering, The University of Tokyo, 2.Medical Device Development and Regulation Research Center, School of Engineering, The University of Tokyo, 3.Tosoh Corporation, 4.The Institute of Medical Science, The University of Tokyo)

キーテクノロジー：水素/重水素交換質量分析法

Keywords:

変異型FcRn,エントロピー駆動,構造ダイナミクス

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