[3S08m] Molecular basis and neuronal function of quality controls for abnormal ribosome dynamics

9:25 AM - 9:40 AM JST(12:25 AM - 12:40 AM UTC)

[3S08m-03] Co-translational aggregation of nascent polypeptides in neurodegenerative disorders

^○Ryo Endo¹, Aki Endo-Murayama ¹, Noriko Takashima¹, Jia Qimin¹, Yuko Saito², Koshi Imami³, Hideki Taguchi⁴, Motomasa Tanaka¹ (1.Lab for Protein Conformation Diseases, CBS, RIKEN, 2.Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 3.Proteome Homeostasis Research Unit, Center for Integrative Medical Sciences, RIKEN, 4.Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)

Keywords:

Ribosome stalling,co-translational aggregation,GGC repeat expansion,NIID

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