[3S08m] Molecular basis and neuronal function of quality controls for abnormal ribosome dynamics | The 98th Annual Meeting of the Japanese Biochemical Society

The 98th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[3S08m]Molecular basis and neuronal function of quality controls for abnormal ribosome dynamics

Wed. Nov 5, 2025 8:45 AM - 10:45 AM JST
Wed. Nov 5, 2025 11:45 PM - 1:45 AM UTC

Room8(Room C-2)

Organizers：Toshifumi Inada（Institute of Medical Science, The University of Tokyo）, Satoru Morimoto（Keio University Regenerative Medicine Research Center）

8:45 AM - 9:05 AM JST(11:45 PM - 12:05 AM UTC)

[3S08m-01]Breakdown of protein quality control mechanisms in motor neuron disease

^○Satoru Morimoto (Keio University Regenerative Medicine Research Center (KRM))

キーテクノロジー：iPS細胞技術

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9:05 AM - 9:25 AM JST(12:05 AM - 12:25 AM UTC)

[3S08m-02]Mechanistic insights into neurodegeneration by RNA G-quadruplex

^○Yasushi Yabuki^1,2, Kazuya Matsuo^1,2, Norifumi Shioda^1,2 (1.Department of Genomic Neurology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2.Graduate School of Pharmaceutical Sciences, Kumamoto University)

キーテクノロジー：Optogenetics

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9:25 AM - 9:40 AM JST(12:25 AM - 12:40 AM UTC)

[3S08m-03]Co-translational aggregation of nascent polypeptides in neurodegenerative disorders

^○Ryo Endo¹, Aki Endo-Murayama ¹, Noriko Takashima¹, Jia Qimin¹, Yuko Saito², Koshi Imami³, Hideki Taguchi⁴, Motomasa Tanaka¹ (1.Lab for Protein Conformation Diseases, CBS, RIKEN, 2.Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 3.Proteome Homeostasis Research Unit, Center for Integrative Medical Sciences, RIKEN, 4.Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)

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9:40 AM - 10:05 AM JST(12:40 AM - 1:05 AM UTC)

[3S08m-04]A Genetic Modifier that Modulates Neurodegeneration Caused by Defective Protein Quality Control

^○Claudio Joazeiro^1,2 (1.Heidelberg University, 2.The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology)

キーテクノロジー：Mouse genetics

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10:05 AM - 10:25 AM JST(1:05 AM - 1:25 AM UTC)

[3S08m-05]Acquisition and adaptation of hard-to-translate sequences in vertebrates

^○Yuichiro Mishima (Kyoto Sangyo University)

キーテクノロジー：Ribosome profiling

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10:25 AM - 10:40 AM JST(1:25 AM - 1:40 AM UTC)

[3S08m-06]Ribosome competition and stress-related translational perturbations drive collision-induced ribosome destabilization

^○Sihan Li¹, Okuto Shounai², Toshifumi Inada¹ (1.The Institute of Medical Science, the University of Tokyo, 2.Graduate School of Pharmaceutical Sciences, Tohoku University)

キーテクノロジー：Yeast genetics

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10:40 AM - 10:45 AM JST(1:40 AM - 1:45 AM UTC)

[3S08m-07]Discussion

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