[1S08m] PROTACs | The 98th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[1S08m]PROTACs

Mon. Nov 3, 2025 9:00 AM - 11:00 AM JST
Mon. Nov 3, 2025 12:00 AM - 2:00 AM UTC

Room8(Room C-2)

Organizers：Mikihiko Naito（The University of Tokyo）, Satoshi Yamanaka（Division of Proteo-Interactome, Proteo-Science Center / Division of Cell-Free Sciences, Proteo-Science Center, Ehime University）

Sponsored by：Transformative Research Areas (A),Shin-biology regulated by protein lifetime

9:00 AM - 9:30 AM JST(12:00 AM - 12:30 AM UTC)

[1S08m-01]PROTACs and molecular glue protein degraders: Molecular mechanism and drug design

^○Alessio Ciulli (University of Dundee)

キーテクノロジー：X-ray crystallography

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9:30 AM - 10:00 AM JST(12:30 AM - 1:00 AM UTC)

[1S08m-02]Non-conventional PROTACs - Turning stress-response pathways into Trash-Anything machines

^○Tim Clausen (Research Institute of Molecular Pathology)

キーテクノロジー：Key Technology

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10:00 AM - 10:20 AM JST(1:00 AM - 1:20 AM UTC)

[1S08m-03]Development of IAP-based PROTACs, SNIPERs

^○Mikihiko Naito (The University of Tokyo)

キーテクノロジー：targeted protein degradation

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10:20 AM - 10:40 AM JST(1:20 AM - 1:40 AM UTC)

[1S08m-04]Targeted protein degradation in mitochondria

^○Minoru Ishikawa (Graduate School of Life Scineces)

キーテクノロジー：標的タンパク質分解

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10:40 AM - 11:00 AM JST(1:40 AM - 2:00 AM UTC)

[1S08m-05]Development and application of protein degrader-dependent interaction analysis method

^○Satoshi Yamanaka^1,2, Yuta Yanagihara³, Kohei Nishino⁴, Yuuki Imai³, Hidetaka Kosako⁴, Tatsuya Sawasaki² (1.Division of Proteo-Interactome, Proteo-Science Center, Ehime University, 2.Division of Cell-Free Sciences, Proteo-Science Center, Ehime University, 3.Division of Integrative Pathophysiology, Proteo-Science Center, Ehime University, 4.Division of Cell Signaling, Fujii Memorial Institute of Advanced Medical Sciences, Tokushima University)

キーテクノロジー：proximity labeling

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