[2S18a] Hijacking and breakdown of gene regulation leading to cancer cell heterogeneity and vulnerability | The 98th Annual Meeting of the Japanese Biochemical Society

The 98th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[2S18a]Hijacking and breakdown of gene regulation leading to cancer cell heterogeneity and vulnerability

Tue. Nov 4, 2025 1:00 PM - 3:00 PM JST
Tue. Nov 4, 2025 4:00 AM - 6:00 AM UTC

Room18(Room 510)

Organizers：Kazuhiko Igarashi（Tohoku University Graduate School of Medicine）, Akira Kobayashi（Doshisha University, Graduate school of Life and Medical Sciences, ）

1:00 PM - 1:05 PM JST(4:00 AM - 4:05 AM UTC)

[2S18a-00]Introduction

^○Kazuhiko Igarashi (Tohoku University Graduate School of Medicine)

Comment()

1:05 PM - 1:23 PM JST(4:05 AM - 4:23 AM UTC)

[2S18a-01]Reprogramming of Cancer Cells via the Transcription Factor NRF3 in Response to Amino Acid Starvation in the Tumor Microenvironment

^○Akira Kobayashi (Doshisha University, Graduate school of Life and Medical Sciences,)

キーテクノロジー：異種移植

Comment()

1:23 PM - 1:41 PM JST(4:23 AM - 4:41 AM UTC)

[2S18a-02]Role of antioxidant selenoproteins in hematopoietic homeostasis and emerging therapeutic strategies for leukemia.

^○Hiromi Yamazaki^1,2, Yumi Aoyama^1,2,3,4, Koutarou Nishimura^1,2, Daichi Inoue^1,2 (1.Department of Cancer Pathology, The University of Osaka, 2.Department of Hematology-Oncology, IBRI, FBRI at Kobe, 3.Department of Hematology, Shinko Hospital, 4.Department of Hematology, Kyoto University)

キーテクノロジー：CRISPRスクリーニング

Comment()

1:41 PM - 2:00 PM JST(4:41 AM - 5:00 AM UTC)

[2S18a-03]Cancer Malignancy and Vulnerability Woven by Iron Metabolism Regulation

^○Mitsuyo Matsumoto¹, Kazuki Nakamura^2,3, Masahiro Rokugo^2,3 (1.MRAM, Tohoku Univ., 2.Dept. of Biochem., Tohoku Univ. Grad. Sch. Med., 3.Dept. of Otolaryngology-HNS, Tohoku Univ. Grad. Sch. Med.)

キーテクノロジー：蛍光FCM、ICP-MS

Comment()

2:00 PM - 2:18 PM JST(5:00 AM - 5:18 AM UTC)

[2S18a-04]Regulatory mechanisms of androgen receptor in prostate cancer progression and drug discovery

^○Satoshi Inoue^1,2 (1.Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2.Satama Medical University)

キーテクノロジー：転写制御

Comment()

2:18 PM - 2:36 PM JST(5:18 AM - 5:36 AM UTC)

[2S18a-05]Understanding dynamics of transcriptional condensates and targeting extrachromosomal DNA (ecDNA) in cancer

^○Hiroshi I. Suzuki (Division of Molecular Oncology, Nagoya University Graduate School of Medicine)

キーテクノロジー：オミクス解析

Comment()

2:36 PM - 2:54 PM JST(5:36 AM - 5:54 AM UTC)

[2S18a-06]Dissecting the mechanisms driving intratumoral heterogeneity in cancer

^○Reo Maruyama^1,2, Liying Yang¹, Kohei Kumegawa², Kenichi Miyata¹ (1.Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, 2.Cancer Cell Diversity Project, NEXT-Ganken Program, Japanese Foundation for Cancer Research)

キーテクノロジー：シングルセル解析

Comment()

2:54 PM - 3:00 PM JST(5:54 AM - 6:00 AM UTC)

[2S18a-07]Discussion

^○Akira Kobayashi (Doshisha University, Graduate school of Life and Medical Sciences,)

Comment()

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