The 98th Annual Meeting of the Japanese Biochemical Society
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Talk

[2T14]Biology of Diseases 01

Tue. Nov 4, 2025 10:50 AM - 11:50 AM JST
Tue. Nov 4, 2025 1:50 AM - 2:50 AM UTC
Room14(Room J)
Organizers：Yoshikazu Johmura（Cancer Research Institute, Kanazawa University）, Akira Kobayashi（Doshisha University）
10:50 AM - 11:00 AM JST(1:50 AM - 2:00 AM UTC)

[2T14-01]Functional analysis of primary cilia in breast CAFs

○Miku Takeda1,2, Tetsuo Kobayashi1, Yoshihiro Mezawa1, Xuhua Dai1,3, Mai Ichikura1, Manami Tominaga1, Mariko Hirano1, Hiroko Onagi4, Ritsuko Sasaki5, Goro Kutomi5, Akira Orimo1 (1.Department of Pathology and Oncology, Juntendo University School of Medicine., 2.Niigata Prefectural Central Hospital., 3. Cancer Molecular Genetics, Tokyo University of Technology., 4.Department of Human Pathology, Juntendo University School of Medicine. , 5.Department of Breast Oncology, Juntendo University School of Medicine.)
キーテクノロジー：マウス Xenograft
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11:00 AM - 11:10 AM JST(2:00 AM - 2:10 AM UTC)

[2T14-02]Exploring the regulatory mechanism of lysosomal exocytosis and the adaptation of cancer cells to the acidic environment

○Yosuke Funato, Osamu Hashizume, Hiroaki Miki (Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University)
キーテクノロジー：ケミカルスクリーニング
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11:10 AM - 11:20 AM JST(2:10 AM - 2:20 AM UTC)

[2T14-03]The effect of dietary stearic acid on colorectal cancer risk is maintained in the intestinal epithelium.

○Kazuaki Nakata1,3, Kazuhiko Yamada2, Norihiro Kokudo2, Yuki I Kawamura1 (1.Japan Institute for Health Security, National Institute for Global Health and Medicine, 2.Japan Institute for Health Security, National Center for Global Health and Medicine, 3.Hokkaido University Faculty of Pharmaceutical Sciences)
キーテクノロジー：オルガノイド培養
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11:20 AM - 11:30 AM JST(2:20 AM - 2:30 AM UTC)

[2T14-04]Elucidation of Cell Cycle Regulatory Mechanisms Involving the Novel Target Protein RPS5 of Coffee-Derived Caffeic Acid

○Motoki Watanabe1, Shogen Boku2, Kaito Kobayashi3, Tomoshi Kameda3, Michihiro Mutoh1, Toshiyuki Sakai4 (1.Department of Molecular-Targeting Prevention, Kyoto Prefectural University of Medicine, 2.Department of Clinical Oncology, Kansai Medical University Hospital, 3.Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 4.Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine)
キーテクノロジー：ケミカルバイオロジー
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11:30 AM - 11:40 AM JST(2:30 AM - 2:40 AM UTC)

[2T14-05]A new molecular targeted cancer therapeutics specifically activate the tumor suppressor p53 pathway via nucleolar stress response

○Yukichika Yasuki1,2, Kazunari Arima1, Keita Yamashita1,2, Junya Sakaguchi1,2, Hidehiko Shitomi1,2, Momo Shiozaki2, Michiko Shimokawa2, Takuto Kawahata2, Tatsuhiko Furukawa2, Kohichi Kawahara2 (1.Prog. Chem., Grad. Sch. Sci. Eng., Kagoshima Univ., 2.Dept. Mol. Onc., Grad. Sch. Med. Dent. Sci., Kagoshima Univ.)
キーテクノロジー：薬剤スクリーニング
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11:40 AM - 11:50 AM JST(2:40 AM - 2:50 AM UTC)

[2T14-06]Regulation of the AKT-mTOR Pathway by Extracellular Lactate and Its Impact on Cancer Cells

○Hiroki Matsumoto, Hiroaki Kajiho, Junko Sasaki, Takehiko Sasaki (Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Science Tokyo)
キーテクノロジー：生化学
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