The 98th Annual Meeting of the Japanese Biochemical Society
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Session Details

Symposium

[3S14m]Front line on development of analytical technologies for next-generation therapeutic antibody evaluation that contributes to drive medical innovation

Wed. Nov 5, 2025 8:45 AM - 10:45 AM JST
Wed. Nov 5, 2025 11:45 PM - 1:45 AM UTC
Room14(Room J)
Organizers：Akiko Ishii-Watabe（National Institute of Health Sciences）, Susumu Uchiyama（Department of Biotechnology, Graduate School of Engineering, The University of Osaka）
Sponsored by：AMED research group “Studies on characterization and quality control strategies of next-generation therapeutic antibodies toward accelerating product development"
8:45 AM - 8:48 AM JST(11:45 PM - 11:48 PM UTC)

[3S14m-00]Introduction

○Akiko Ishii (National Institute of Health Sciences)
Comment()
8:48 AM - 9:11 AM JST(11:48 PM - 12:11 AM UTC)

[3S14m-01]Evaluation of structural properties of therapeutic antibodies by Multi-attribute method

○Noritaka Hashii (Division of Biological Chemistry and Biologicals, National Institute of Health Sciences)
キーテクノロジー：LC/MS
Comment()
9:11 AM - 9:34 AM JST(12:11 AM - 12:34 AM UTC)

[3S14m-02]Site-Specific Higher-Order Structure Analysis of Therapeutic Antibodies by NMR Spectroscopy

○Koichi Kato1,2, Maho Yagi-Utsumi1,2, Saeko Yanaka1,3 (1.Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 2.Graduate School of Pharmaceutical Sciences, Nagoya City University, 3.Institute of Integrated Research, Institute of Science Tokyo)
キーテクノロジー：NMR
Comment()
9:34 AM - 9:57 AM JST(12:34 AM - 12:57 AM UTC)

[3S14m-03]Capturing molecular interactions of antibodies through Raman spectroscopy

○Satoru Nagatoishi1, Yusui Sato2, Takashi Kinoshita2, Kouhei Tsumoto1,3 (1.MDRCC, Sch. of Engineer., The Univ. of Tokyo, 2.HORIBA, Ltd., 3.Dep. of Bioeng, Sch. of Engineer., The Univ. of Tokyo)
キーテクノロジー：ラマン分光
Comment()
9:57 AM - 10:20 AM JST(12:57 AM - 1:20 AM UTC)

[3S14m-04]Development of structural analysis method for therapeutic antibodies using CRYO EM

○Masato Kiyoshi1, Chihong Song2, Saeko Yanaka2, Koichi Kato2, Kazuyoshi Murata2, Akiko Ishii-Watabe1 (1.National Institute of Health Sciences , 2.ExCELLS)
キーテクノロジー：クライオ電子顕微鏡
Comment()
10:20 AM - 10:45 AM JST(1:20 AM - 1:45 AM UTC)

[3S14m-05]Development of rapid formulation optimization method for next generation antibody drugs

○Susumu Uchiyama (Department of Biotechnology, Graduate School of Engineering, The University of Osaka)
キーテクノロジー：凝集体評価法
Comment()
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