[3T09] Proteins 04 | The 98th Annual Meeting of the Japanese Biochemical Society

Session Details

Talk

[3T09]Proteins 04

Wed. Nov 5, 2025 10:50 AM - 11:50 AM JST
Wed. Nov 5, 2025 1:50 AM - 2:50 AM UTC

Room9(Room 104)

Organizers：Atsushi Saito（Department of Frontier Science and Interdisciplinary Research, Faculty of Medicine, Kanazawa University）, Yoshimasa Sagane（Tokyo University of Agriculture）

10:50 AM - 11:00 AM JST(1:50 AM - 2:00 AM UTC)

[3T09-01]Regulation of the terminal structure of aggregated proteins and its impact on the efficiency of protein disaggregation by ClpB chaperone

^○Kento Suzuki¹, Takashi Yamasaki¹, Akiyoshi Oda¹, Tatsuya Nojima², Yo-hei Watanabe^1,3 (1.Department of Biology, Graduate School of Natural Science, Konan University, 2.Cell Biology Center, Institute of integrated Research, Cell Biology Center, Institute of Science Tokyo, 3.Institute for Integrative Neurobiology, Konan University)

キーテクノロジー：凝集タンパク質の末端構造の評価

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11:00 AM - 11:10 AM JST(2:00 AM - 2:10 AM UTC)

[3T09-02]Learning What AlphaFold2 Learned

^○Kosei Nozaki, George Chikenji (Dept. of Appl. Phys., Grad.Sch.of Eng., Nagoya Univ)

キーテクノロジー：AlphaFold2

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11:10 AM - 11:20 AM JST(2:10 AM - 2:20 AM UTC)

[3T09-03]Elucidation of the Regulatory Mechanism of obesity: Leptin Receptor Stabilization by the ER Stress Sensor IRE1α

^○Haruto Yoshida¹, Yasuhiro Noda¹, Takumi Matsubara¹, Tomoki Tsuchida¹, Tadashi Nakagawa^1,2, Toru Hosoi¹ (1.Fac. Pharm. Sci., Sanyo-Onoda City Univ., 2.Grad. Sch. Med., Tohoku Univ.)

キーテクノロジー：タンパク質相互作用解析

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11:20 AM - 11:30 AM JST(2:20 AM - 2:30 AM UTC)

[3T09-04]Identification of transmembrane degrons facilitating ER-associated degradation of CFTR

^○Saori Kato, Yuka Kamada, Tsukasa Okiyoneda (Dept Biomed Sci Kwansei Gakuin Univ)

キーテクノロジー：HiBiT degradation assay

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11:30 AM - 11:40 AM JST(2:30 AM - 2:40 AM UTC)

[3T09-05]Development of a novel targeted-protein degradation system based on the ClpB chaperone with potent disaggregase activity

^○Momoka Tamura¹, Masashi Miki¹, Ayari Tatsumi², Yo-hei Watanabe^1,2,3 (1.Department of Biology, Graduate School of Natural Science, Konan University, 2.Department of Biology, Faculty of Science and Engineering, Konan University, 3.Institute for Integrative Neurobiology, Konan University)

キーテクノロジー：融合タンパク質

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11:40 AM - 11:50 AM JST(2:40 AM - 2:50 AM UTC)

[3T09-06]Mechanisms for maintaining proteostasis under hyperosmotic stress

^○Kouta Nakadai^1,2, Hikaru Tsuchiya³, Takuya Tomita², Yasushi Saeki² (1.Graduate School of Frontier Sciences, The University of Tokyo, 2.The Institute of Medical Science, The University of Tokyo, 3.Graduate School of Medicine, Juntendo University)

キーテクノロジー：LC-MS/MS

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