[3T15] Medical Inovation 02 | The 98th Annual Meeting of the Japanese Biochemical Society

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Talk

[3T15]Medical Inovation 02

Wed. Nov 5, 2025 10:50 AM - 11:50 AM JST
Wed. Nov 5, 2025 1:50 AM - 2:50 AM UTC

Room15(Room K)

Organizers：Etsuro Ohta（Kitasato University）, Yuji Hara（University of Shizuoka）

10:50 AM - 11:00 AM JST(1:50 AM - 2:00 AM UTC)

[3T15-01]Development of a method for predicting human iPSC differentiation using extracellular vesicle proteins in cell culture medium

^○Mei Mikami, Shunsuke Hoshina, Eri Katsuno, Kansei Takashita, Daisuke Takakura, Nana Kawasaki (Graduate school of Medical Life Science, Yokohama City University)

キーテクノロジー：DIA-MS

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11:00 AM - 11:10 AM JST(2:00 AM - 2:10 AM UTC)

[3T15-02]Metabolic analysis of pyruvate dehydrogenase deficiency using iPS cells

^○Tomoyuki Abe¹, Eiji Sakashita², Kenji Kuroiwa², Katsumi Kasashima², Yutaka Inoki², Yuki Taguchi², Eriko Ohta², Chiyoko Kato², Shigeaki Miyabayashi³, Kaoru Tominaga², Hitoshi Endo² (1.Center for Development of Advanced Medical Technology, Jichi Medical University, 2.Department of Biochemistry, Jichi Medical University, 3.Miyabayashi KODOMO Clinic)

キーテクノロジー：エネルギー代謝

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11:30 AM - 11:40 AM JST(2:30 AM - 2:40 AM UTC)

[3T15-03]Use of human intestinal organoids identified a natural compound that protects intestinal inflammation

^○Yu Takahashi¹, Zhongwei Zhang², Izumi Tanaka², I-Ting Lee¹, Takayoshi Okabe³, Hirotatsu Kojima³, Yosuke Kurashima², Ryuichiro Sato⁴, Yoshio Yamauchi¹ (1.Food Biochemistry Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.Department of Innovative Medicine, Graduate School of Medicine, Chiba University, 3.Drug Discovery Initiative, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 4.Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo)

キーテクノロジー：ヒト小腸オルガノイド

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11:40 AM - 11:50 AM JST(2:40 AM - 2:50 AM UTC)

[3T15-04]Targeting Cancer Cell Mitochondria with Novel Salinomycin-Phosphonium Conjugates

^○Gwan Yong Lim¹, Magdalena Mielczarek-Puta¹, Marta Jedrzejczyk², Michal Sulik², Adam Huczynski², Marta Struga¹ (1.Chair and Department of Biochemistry, Faculty of Medicine, Medical University of Warsaw, 2.Department of Medical Chemistry, Adam Mickiewicz University, Poznan, Poland)

キーテクノロジー：Mitochondrial targeting

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11:20 AM - 11:30 AM JST(2:20 AM - 2:30 AM UTC)

[3T15-05]Abemaciclib ameliorates autophagy dysfunction induced by progranulin insufficiency

^○Yoshinori TANAKA¹, Misaki Kikuchi¹, Hirotsugu Hino² (1.Biochem. Unit, Fac. of Vet. Med., Okayama Univ. of Sci., 2.Div. of Anat. Sci., Dept. of Funct. Morpho., Nihon Univ. Sch. of Med.)

キーテクノロジー：レスキュー実験

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11:10 AM - 11:20 AM JST(2:10 AM - 2:20 AM UTC)

[3T15-06]Intranasal administration of linear ubiquitin chain assembly complex (LUBAC) inhibitor ameliorates disease pathology in a mouse model of amyotrophic lateral sclerosis.

^○Yukari Hatanaka¹, Daisuke Oikawa¹, Kazuto Tsukita², Takami Tomiyama³, Yosuke Demizu^4,5,6, Yoshinosuke Usuki⁷, Fuminori Tokunaga^1,8 (1.Dept. of Med. Biochem., Grad. Sch. of Med., Osaka Metropol. Univ., 2.Dept. of Neurol., Grad. Sch. of Med., Kyoto Univ., 3.Dept. of Transl. Neurosci., Grad. Sch. of Med., Osaka Metropol. Univ., 4.Div. of Org. Chem., Nat. Inst. of Health Sci., 5.Grad. Sch. of Med. Life Sci., Yokohama City Univ., 6.Grad. Sch. of Med., Dentist. and Pharm. Sci., Div. of Pharm. Sci. of Okayama Univ., 7.Dept. of Chem., Grad. Sch. of Sci., Osaka Metropol. Univ., 8.Res. Inst. for Drug Discov. Sci., Osaka Metropol. Univ.)

キーテクノロジー：経鼻投与

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