Presentation Information
[20p-P09-3]Chronopotentiometry of free-standing bilayer lipid membranes formed over an aperture in a Si/Si3N4 chip.
〇(M2)Yoshihiro Shimada1, Daiki Hiramatsu1, Masataka Moriya1, Hiroshi Shimada1, Daisuke Tadaki2, Ayumi Hirano-Iwata2, Yoshinao Mizugaki1 (1.The Univ. of Electro-Comm., 2.Tohoku Univ.)
Keywords:
folding method,electroporation,DPhPC
Chronopotentiometry were taken on free-standing bilayer lipid membranes formed over an aperture in a Si/Si3N4 chip. We observed voltage saturated at a measurement taken about 3 hours after formed BLM. However, we observed voltage drop at a measurement taken about 1 day after formed BLM. This voltage drop suggests electroporation, and we believe this is the effect of changes over time in the BLM that formed. Also, compared to a previous study, the current density at which electroporation occurs is large and the time to reach it is long, and we believe this is because of the high resistance of the formed BLM.