Presentation Information

[23p-12C-3]Mechanical characterization of human skin by use of Brillouin scattering microscopy

〇(M1)Naoya Okubo1, Eiji Hase2, Yu Tokizane2, Takeo Minamikawa3,2, Takeshi Yasui2 (1.Grad. Sch. Sci. Tech. Innov. Sci. Tokushima Univ., 2.pLED, Tokushima Univ., 3.Grad. Sch. Engg. Sci., Osaka Univ.)

Keywords:

Brillouin scattering microscope,Biophotophysical Properties,Mechanical characterization

Analysis of the mechanical properties of skin is important for a wide range of applications, including the diagnosis of diseases and aging. However, it has been difficult to perform the mechanical analysis while identifying the distribution of collagen and elastin, which are the major extracellular matrix of the skin. In this study, we constructed an optical microscope system that integrates SHG microscopy and two-photon excitation fluorescence microscopy with Brillouin scattering microscopy in order to investigate the relationship between the distribution of collagen and elastin and local mechanical properties.