[24a-1BM-1~11] 12.7 Biomedical Engineering and Biochips

11:15 AM - 11:30 AM JST(2:15 AM - 2:30 AM UTC)

[24a-1BM-9] Biosensing with Surface Charge Modulated Graphene Field-Effect Transistors Beyond Nonlinear Electrolytic Screening

〇Tomomi Nakano¹, Shota Ushiba¹, Takao Ono², Shinsuke Tani¹, Masahiko Kimura¹, Kazuhiko Matsumoto² (1.Murata Manufacturing Co., Ltd., 2.SANKEN, Osaka Univ.)

Keywords:

graphene,FET,biosensor

A field-effect transistor biosensor (GFET) using graphene detects changes in surface potential due to the charge of proteins, which are the detection targets. Graphene is negatively charged in solution, so unless the surface charge is modulated, nonlinear electric field screening at the interface between graphene and solution will reduce the high sensitivity of the GFET. In this study, we detected C-reactive protein (CRP) using a surface-charge-modulated GFET (SCM-GFET), which modulates the negative surface charge of graphene by modifying it with a positively charged compound. did.