Presentation Information
[24p-1BN-7]Cell sorting based on label-free spectroscopy
〇Kotaro Hiramatsu1 (1.Kyushu Univ.)
Keywords:
Cell sorting,Raman spectroscopy
Cell sorting is an important tool in biological research and medicine, and is frequently used to separate diverse cell populations based on their unique characteristics. In particular, when considering medical applications of cell sorting, there is a great need for a label-free method to measure cell characteristics and sort cells based on them. Raman-activated cell sorting (RACS) has attracted much attention in recent years because it can distinguish cells based on their intracellular chemical composition without the need for labeling, but the RACS demonstrated so far have not achieved a practical level of sensitivity, throughput, or bandwidth.
In this talk, I will discuss the principle and application of our recently realized high throughput (~ 50 cells/second) broadband RACS in the fingerprint region (300-1,600 cm-1), and will also clarify the technical issues that need to be solved in the future for medical applications of this technique.
In this talk, I will discuss the principle and application of our recently realized high throughput (~ 50 cells/second) broadband RACS in the fingerprint region (300-1,600 cm-1), and will also clarify the technical issues that need to be solved in the future for medical applications of this technique.