[10p-N104-1~10] 3.3 Biomedical optics

3:45 PM - 4:00 PM JST(6:45 AM - 7:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[10p-N104-9] Recovery of Raman signals under autofluorescence via extensive averaging and SERDS

〇(M1C)Kota Hayashi¹, Takuya Koyama², Takashi Katagiri² (1.Graduate School of Science and Engineering, University of Toyama, 2.Faculty of Engineering, University of Toyama)

Keywords:

Shifted Excitation Raman Difference Spectroscopy,Autofluorescence,Noise reduction

In Raman sensing of biological tissues, strong autofluorescence significantly reduce the accuracy of lesion classification and quantitative measurement. Shifted Excitation Raman Difference Spectroscopy (SERDS) has been proposed as a method to separate Raman signals from autofluorescence. In this study, we aim to clarify the effect of SERDS, which contributes to noise reduction through multiple averaging, and to propose a method to extract Raman spectra from samples that are difficult to measure due to strong autofluorescence.