[7p-N306-1~15] 12.6 Nanobiotechnology

2:00 PM - 2:15 PM JST(5:00 AM - 5:15 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[7p-N306-3] Development of a Novel Laser-Induced Molecular Condensation Method and
Its Application to Promotion of Enzymatic Reactions

〇Momoka Fujita¹, Shuma Matsumoto¹, Ren Shirata¹, Genki Fukasawa², Takahisa Matsuzaki¹, Shinya Tsukiji³, Tomoaki Matsuura⁴, Hiroshi Yoshikawa¹ (1.Grad. Sch. Eng., Univ. Osaka, 2.Grad. Sch. Life Sci. Tech., Science Tokyo, 3.Life Sci. and Applied Chem., NITech, 4.ELSI, Science Tokyo)

Keywords:

optical trapping,biomolecule

Our molecular concentration method is based on the physical effects of a focused laser beam and its process does not involve specific photochemical reactions, so that allows its application to a wide range of biomolecular systems. In this study, we successfully demonstrated localized activation of enzymatic reactions via laser-induced concentration, revealing for the first time that this approach can be applied to the spatiotemporal control of biomolecular functions. In the future, this method is expected to contribute to the elucidation and regulation of various biological phenomena occurring in crowded intracellular environments.