[14p-K502-1~12] 2.4 Life Sciences, Medical applications, Space and Earth Environment, Radiation Education

3:30 PM - 3:45 PM JST(6:30 AM - 6:45 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[14p-K502-10] In vivo Imaging of Gold Nanoparticles in Mice Using Photon-Counting CT for Tumor Detection

〇(B)Yu Furuta¹, Makoto Arimoto¹, Takahiro Tomoda¹, Fitri Lucyana¹, Minori Oshima¹, Satoshi Kobayashi¹, Hiroki Kawashima¹, Kenichiro Okumura¹, Naoki Ohno¹, Zyun Kataoka², Ryotaro Minagawa², Takahiro Ro², Shinsuke Terazawa³, Satoshi Shiota³ (1.Kanazawa Univ., 2.Waseda Univ., 3.Proterial Ltd.)

Keywords:

Photon-Counting CT,Silicon Photomultiplier (SiPM),Au nanoparticles

In this presentation, we will discuss the evaluation of the distribution of gold nanoparticles, which tend to accumulate in tumors due to the Enhanced Permeability and Retention (EPR) effect, using a photon-counting CT developed with a combination of a high-speed scintillator (YGAG:Ce) and a Silicon Photomultiplier (SiPM). The study focuses on in vivo imaging of gold nanoparticles in mice with implanted tumors.