[15p-K403-1~15] 12.7 Biomedical Engineering and Biochips

4:30 PM - 4:45 PM JST(7:30 AM - 7:45 AM UTC)

[15p-K403-8] Fabrication and evaluation of microneedle sensors functionalized with glucose-responsive fluorescent hydrogels

〇Masahiro Fukuhara¹, Yukihiro Kanda^1,2, Hiroaki Takehara^1,2, Kevin Barthelmes³, Akira Matsumoto^1,3, Takanori Ichiki^1,2 (1.Tokyo Univ., 2.iCONM, 3.Science Tokyo)

Keywords:

microneedle,optical measurement,glucose sensing

Interstitial fluid (ISF) has been widely studied for its diagnostic potential, yet sensing ISF within living body remains a significant challenge. Microneedles have garnered attention as a minimally invasive technology capable of accessing biological tissues and hold promise as a tool for ISF sensing. In this study, we fabricated a high-aspect-ratio microneedle device embedded with functional fluorescent hydrogel at its tip and evaluated its fluorescence sensing capability for glucose solutions as a proof of concept for this technology.