[16p-WL1_201-1~14] Innovation in Physical Chemistry and Quantum Life Sciences via Photothermal Conversion

4:05 PM - 4:40 PM JST(7:05 AM - 7:40 AM UTC)

[16p-WL1_201-8] Cell-penetrating peptide-based cytosolic drug delivery technology from biophysical and quantum life science perspectives

〇Ikuhiko Nakase^1,2,3 (1.Grad. Sch. of Sci., Osaka Metropolitan Univ. (OMU), 2.RILACS, OMU, 3.Inst. for Chem. Biol., OMU)

Keywords:

cell-penetrating peptides,Light-enhanced concentration system,Inkjet system

This presentation will focus on the technological development of drug delivery methods based on cell-penetrating peptides (CPPs). It will cover novel CPP development from biophysical and quantum life science perspectives (e.g., peptides derived from toxin proteins), light-enhanced concentration (e.g., delivery of anticancer active peptides), targeted cytosolic delivery to cells using inkjet systems (e.g., application for IgG antibody delivery), and the technologies for controlling the intracellular transport of extracellular vesicles. The potential for future medical applications will also be discussed.