[17a-WL1_301-1~11] 12.7 Biomedical Engineering and Biochips

11:15 AM - 11:30 AM JST(2:15 AM - 2:30 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[17a-WL1_301-9] Effect of CPE on EIS-based cell biosensing

〇Keita Kishimoto¹, Yuto Matsubayashi¹, Shigeyasu Uno¹ (1.Ritsumeikan Univ.)

Keywords:

Electrochemical Impedance Spectroscopy,Living Cell Monitoring,Constant Phase Element

We analyzed the effect of the Constant Phase Element (CPE), caused by electrode surface roughness, on cell sensing using Electrochemical Impedance Spectroscopy via simulation. The results confirmed that cell-substrate impedance increases as the CPE exponent decreases. Additionally, regarding the detection of degranulation responses, a slight reduction in peak sensitivity and a shift toward higher frequencies were observed. This study is expected to enable highly accurate simulations that align with actual measurement behaviors.