Presentation Information
[17p-S2_201-1]Prototyping of CLS-7: a brain TOF-DOI PET with 1-mm resolution
〇Hideaki Tashima1, Go Akamatsu1, Kurumi Narita1, Yuma Iwao1, Eiji Yoshida1, Miwako Takahashi1, Taiga Yamaya1 (1.QST)
Keywords:
brain PET,time of flight (TOF),depth of interaction (DOI) measurement
High-resolution brain PET can visualize radiopharmaceutical distributions in microscopic brain regions, enabling functional evaluation of small regions that were previously difficult to assess with conventional PET systems. This is expected to greatly improve diagnostic performance for brain diseases.
In this study, we developed a prototype brain PET system named CLS-7. The system employs our TOF-DOI detector (CLS detector), which achieves both high time-of-flight (TOF) resolution and depth-of-interaction (DOI) measurement. Spatial resolution was evaluated using a 22Na rod phantom. Image reconstruction was performed using the ordered subset expectation maximization (OSEM) method. The reconstructed images clearly resolved 1-mm-diameter rods. These results demonstrate that CLS-7 achieves spatial resolution approaching the theoretical limit for a head-sized PET system.
In this study, we developed a prototype brain PET system named CLS-7. The system employs our TOF-DOI detector (CLS detector), which achieves both high time-of-flight (TOF) resolution and depth-of-interaction (DOI) measurement. Spatial resolution was evaluated using a 22Na rod phantom. Image reconstruction was performed using the ordered subset expectation maximization (OSEM) method. The reconstructed images clearly resolved 1-mm-diameter rods. These results demonstrate that CLS-7 achieves spatial resolution approaching the theoretical limit for a head-sized PET system.