Presentation Information

[18p-W2_401-10]Demonstration of Weak Intensity Change Detection Using Self-Reset Image Sensor for In-vivo Experiments

〇(M1)Kenji Morimoto1, Subaru Iwaki1, Ryoma Okada1, Yoshinori Sunaga1, Makito Haruta1,2, Hironari Takehara1, Hiroyuki Tashiro1,3, Jun Ohta1, Kiyotaka Sasagawa1 (1.Nara Institute of Science and Technology, 2.Chitose Institute of Science and Technology, 3.Kyushu University)

Keywords:

CMOS image sensor,Self reset

In this study, we demonstrate that a self-reset image sensor is capable of detecting weak intensity changes as small as 0.1%. The self-reset image sensor achieves a high signal-to-noise ratio by avoiding pixel saturation and detecting several million electrons. In the demonstration experiment, small intensity changes were generated using two light sources with different intensities, and measurements were performed using a self-reset image sensor. These results indicate that the proposed sensor is promising for application to brain functional imaging using voltage-sensitive dyes.