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Tumor-suppressive cell competition driven by a "kick-me-out" signal, FGF21

There are growing evidence showing that the development and progression of cancer are governed not only by the accumulation of multiple genetic mutations but also by the interaction between cancerous cells and their surrounding environment. Understanding this complicated mechanism has become an urgent challenge toward intractable cancers. In this symposium, we present the latest insights into systemic signals, including cellular interactions and metabolism controlling the "natural history of cancer" from precancerous stages to malignancy. We will discuss about the principles of cancer regulation through molecular, cellular, and interorgan networks.

The Meeting of the Japan Society for Cell Biology

The 76th Annual Meeting of the Japan Society for Cell Biology

The 76th Annual Meeting of the Japan Society for Cell Biology

[1C02]Tumor-suppressive cell competition driven by a "kick-me-out" signal, FGF21

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