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Quantifying the number of intracellular organelles using spatial image correlation spectroscopy (SICS)

It is essential that the homeostasis of organelle quantity and quality is maintained through strict control. However, under processes such as development and cell differentiation, the homeostatic system may be intentionally released, resulting in dynamic changes in the quantity and quality of organelles. Furthermore, its fluctuations can cause various diseases and aging, making the understanding of the system critical. However, to date, there have been limitations in the technology that can monitor and evaluate quantitative and qualitative changes in organelles, creating a barrier to understanding cellular homeostasis. Experts attempting to evaluate the quantity and quality of organelles using new parameters will explore the mysteries of cellular homeostasis.

Maintenance/disruption of organelle "quantity" and "quality"

The 76th Annual Meeting of the Japan Society for Cell Biology

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[3D13]Quantifying the number of intracellular organelles using spatial image correlation spectroscopy (SICS)

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