Session Details

[3S-Da]Maintenance/disruption of organelle "quantity" and "quality"

Fri. Jul 19, 2024 3:00 PM - 5:30 PM JST
Fri. Jul 19, 2024 6:00 AM - 8:30 AM UTC
Venue D 2F Conference Room 202
Organizers:Ryo Ushioda(Kyoto Sangyo University), Kota Yanagitani(Osaka University)
It is essential that the homeostasis of organelle quantity and quality is maintained through strict control. However, under processes such as development and cell differentiation, the homeostatic system may be intentionally released, resulting in dynamic changes in the quantity and quality of organelles. Furthermore, its fluctuations can cause various diseases and aging, making the understanding of the system critical. However, to date, there have been limitations in the technology that can monitor and evaluate quantitative and qualitative changes in organelles, creating a barrier to understanding cellular homeostasis. Experts attempting to evaluate the quantity and quality of organelles using new parameters will explore the mysteries of cellular homeostasis.

Opening Remarks

[3D08]The Secret of Organelle-Abundance Homeostasis: Aggressive Inquiry

*Kota Yanagitani1,2, Asato Uenosono1, Fumiyo Ikeda1,2, Itakura Eisuke3, Shunsuke Ishii4, Reiko Kamegai1 (1. Grad. Sch. Front. Biosci., Osaka Univ., 2. Med. Inst. Bioreg, Kyushu Univ., 3. Dep. Bio., Grad. Sch. Sci., Chiba Univ., 4. Dep. Bio., Grad. Sch. Sci & Engi., Chiba Univ.)

[3D09]Organelle landscape analysis using a multi-parametric particle-based method

*Ikuko Koyama-Honda1, Yoshitaka Kurikawa1, Noboru Mizushima1 (1. The Univ. of Tokyo, Med)

[3D10]A novel ratio-type pH probe unveiled a decrease in lysosomal luminal pH induced by amino acid starvation

*Yoshihiko Kuchitsu1,2, Takuya Kuriyama1, Toa Igarashi1, Ayumu Nomoto1, Kenjiro Hanaoka3, Tomohiko Taguchi1 (1. Graduate School of Life Sciences, Tohoku University, 2. Department of Anatomy and Histology, Fukushima Medical University School of Medicine, 3. Keio university, faculty of pharmacy)

[3D11]Peroxisomal quantity and quality during early mammalian development

*Ayumu Sugiura1, Junji Yamaguchi1, Isei Tanida1, Yasuo Uchiyama1, Hikari Taka1, Yoshiki Miura1, Yuhkoh Satoh2, Sato Ken2, Shohei Uchinomiya3, Toshihiko Fujimori4, Yasushi Okazaki1,5 (1. Juntendo Univ. Graduate Scholl of Medicine, 2. Gunma Univ. Institute for Molecular and Cellular Regulation, 3. Kyushu. Univ. Graduate School of Pharmaceutical Sciences, 4. National Institute for Basic Biology, Division of Embryology, 5. RIKEN Center for Integrative Medical Sciences)

[3D12]Size control system of nuclear size in Xenopus embryos

*Yuki Hara1, Mizuki Ikeda1, Yuto Tanaka1, Tatsuya Shohoji1 (1. Yamaguchi Univ., Faculty of Science)

[3D13]Quantifying the number of intracellular organelles using spatial image correlation spectroscopy (SICS)

*Yuta Hamada1, Akira Kitamura2 (1. Graduate School of Life Science, Hokkaido University, 2. Faculty of Advanced Life Science, Hokkaido University)

[3D14]Roles of an ER-resident protein PDZD8 in the fromation of ER-mitochondria contact sites

*Yusuke Hirabayashi1, Koki Nakamura1, Saeko Aoyama-Ishiwatari1, Takahiro Nagao1, Haruo Nishi1, Christopher J. Obara2, Mohammadreza Paaran4, Hidetaka Kosako3 (1. University of Tokyo, School of Engineering, 2. Janelia Research Campus, Howard Hughes Medical Institute,, 3. Tokushima University, Institute of Advanced Medical Sciences, 4. Columbia University)

[3D15]Redox environment that ensures the “quality” of ER and its evaluation

*Ryo Ushioda1,2 (1. Faculty of Life Sciences, Kyoto Sangyo University, 2. Institute for Protein Dynamics, Kyoto Sangyo University)

Closing Remarks