[3AO-E] Intracellular Transport, Organelles, and Biological Membranes IV

11:02 AM - 11:14 AM JST(2:02 AM - 2:14 AM UTC)

[3AO-E-02] Elucidation of a Novel Regulatory Mechanism of Macropinocytosis via the PI(3,4)P2-Plekhs1 Axis and Its Contribution to Gut Immune Surveillance

*Keisuke Tanaka¹, Nobuhide Kobayashi^2,3, Shunsuke Takano², Taichi Masuyama², Yoichiro Fujioka⁴, Yusuke Ohba⁴, Koji Hase^2,5,6, Shunsuke Kimura^1,2 (1. Laboratory of Mucosal Immunology and Epithelial Biology, Faculty of Pharmaceutical Sciences, Hokkaido University, 2. Division of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Science, Keio University, 3. Department of Bacteriology, Graduate School of Medical Sciences, Kanazawa University, 4. Department of Cell Physiology, Faculty of Medicine, Hokkaido University, 5. Division of Commensal Biology, The Institute of Medical Science, The University of Tokyo (IMSUT), 6. Institute of Fermentation Sciences (IFeS), Faculty of Food and Agricultural Sciences, Fukushima University)

Keywords:

M cell,Macropinocytosis,PIPs: Phosphatidylinositol phosphates,Gut immune system,IgA: immunoglobulin A

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