[1AS-01-01]Deep Generative Models for Biological Dynamics and Molecular Design
○Teppei Shimamura1(1. Science Tokyo)
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2024 - 2025
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| Year : | 2024 - 2025 |
Search across all events. Up to 10,000 search results will be displayed.
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Search Results(8,086)
[1AS-01-02]Spatial multi-omics analysis for elucidation of transcriptional regulatory networks associated with lung cancer progression and aberrant cell differentiation
○Ayako Suzuki1(1. Grad. Sch. of Front. Sci., Univ. of Tokyo)
[1AS-01-03]Prediction of Transcriptional Responses to Genetic Perturbations Using DNA Language Models
○Itoshi Nikaido1,2(1. Institute of Science Tokyo, 2. RIKEN)
[1AS-01-04]New Frontiers in Peptide Science driven by Directed Evolution and Single-Molecule Measurement
○Kosuke Fujishima1(1. Institute of Science Tokyo)
[1AS-01-05(1P-334)]From Materials to Metabolism: Deep-Layer Multi-Omics Reveals Hidden Biocompatibility Signatures
○Hiroyuki Okada1,2, Shohei Ishikawa3, Masaru Mori4, Akiyoshi Hirayama5, Yoshiaki Kitaura1, Asuka Terashima6, Yasunori Omata6,2, Ung-il Chung1,7, Kazuharu Arakawa5, Keiji Numata8,5,9, Takamasa Sakai3, Hironori Hojo1,7(1. Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the Univ. of Tokyo, 2. Dept. of Orthopaedic Surgery, the Univ. of Tokyo, 3. Department of Chemistry and Biotechnology, Graduate School of Engineering, the Univ. of Tokyo, 4. Institutes of Innovation for Future Society, Nagoya University, 5. Institute for Advanced Biosciences, Keio University, 6. Bone and Cartilage Regenerative Medicine, the Univ. of Tokyo Hospital, 7. Department of Bioengineering, Graduate School of Engineering, the Univ. of Tokyo, 8. Department of Material Chemistry, Graduate School of Engineering, Kyoto Univ., 9. Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science)
[1AS-01-06(1P-188)]Exploring the dark proteome through translation initiation profiling
○Kazuya Ichihara1, Taichi Shiraishi1, Haruhiko Morita2, Chisa Shiraishi1, Atsushi Hatano3, Serina Tokita3,4, Takayuki Kanaseki3,4, Shungo Adachi5, Yutaka Suzuki6, Masaki Matsumoto3, Teppei Shimamura2,7, Akinobu Matsumoto1(1. Division of Biological Science, Graduate School of Science, Nagoya University, 2. Department of Computational and Systems Biology, Division of Biological Data Science, Medical Research Laboratory, Institute for Integrated Research, Institute of Science Tokyo, 3. Graduate School of Medical and Dental Sciences, Niigata University, 4. Department of Pathology, Sapporo Medical University, 5. Department of Proteomics, National Cancer Center Research Institute, 6. Univ. Tokyo, 7. Nagoya Univ.)
[1AS-01-07]Understanding cancer malignancy through multi-omics analyses
○Tsuyoshi Osawa Osawa1(1. The University of Tokyo)
[1PS-01-01]Understanding and preventing egg aneuploidy
○Tomoya Kitajima1(1. RIKEN BDR)
[1PS-01-02]Mechanism and in vitro reconstitution of human germ-cell development
○Mitinori Saitou1,2,3(1. Institute for the Advanced Study of Human Biology, Kyoto University, 2. Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, 3. Center for iPS Cell Research and Application, Kyoto University)
[1PS-01-03]Development of a signaling center-based human embryo model
○Hiroaki Okae1, Akira Oike1, Asato Sekiya1, Riu Kondo1(1. Kumamoto University)
[1PS-01-04]Human-specific regional fluidization of neuroepithelia
○Miki Ebisuya-Matsuda Ebisuya1(1. TU Dresden)
[1PS-01-05]Signaling Induced Plasticity in Naive PSCs Enables Direct & Transgene-Free Generation of Advanced Mouse and Human SEMs
○Jacob H Hanna1(1. Weizmann Institute of Sceince)
[1AS-02-01]PIWI-piRISC assembly defect underlying infertility: insights from Drosophila and mouse models
○Mikiko C Siomi1(1. Graduate School of Science The University of Tokyo)
[1AS-02-02(1P-009)]Development of L1 Retrotransposon and eccDNA Reporters for Probing cGAS-STING-Mediated Innate Immune Responses
○Herve Dushimyineza1,2, Jiawei Cai3, Tomoichiro Miyoshi4, Makoto T. Hayashi2,5(1. Graduate School of Biostudies, Kyoto University , 2. IFOM-KU Joint-Research Laboratory, Graduate School of Medicine, Kyoto University , 3. Nutrition & Biomedicine, Graduate School of Science, Technical University of Munich, 4. Laboratory for Retrotransposon Dynamics, RIKEN Center for Integrative Medical Sciences (IMS), 5. Chromosome Instabilities Unit, IFOM ETS, The AIRC Institute of Molecular Oncology)
[1AS-02-03]Centromere-targeted integrations of an LTR retrotransposon via CENH3 chromatin in Arabidopsis
○Sayuri Tsukahara1, Alexandros Bousios2, Estela Perez-Roman2, Sota Yamaguchi1, Basile Leduque3, Aimi Nakano1, Matthew Naish4, Akihisa Osakabe1, Atsushi Toyoda5, Hidetaka Ito6, Alejandro Edera3, Sayaka Tominaga1, Juliarni Juliarni1, Kae Kato7, Shoko Oda1, Soichi Inagaki1, Zdravko Lorković8, Kiyotaka Nagaki9, Frédéric Berger8, Akira Kawabe10, Leandro Quadrana3, Ian Henderson4, Tetsuji Kakutani1(1. The University of Tokyo, 2. University of Sussex, 3. Universite Paris Saclay, 4. University of Cambridge, 5. National Institute of Genetics, Center for Genetic Resource Information, 6. Hokkaido University, 7. National Institute of Genetics, Department of Integrated Genetics, 8. Gregor Mendel Institute (GMI), 9. Okayama University, 10. Kyoto Sangyo University)
[1AS-02-04]Understanding the disease risk of human transposons by population genetics
○Shohei Kojima1,2(1. Keio Univ., 2. RIKEN)
[1AS-02-05]Exploring the evolutionary link between CRISPR-Cas and transposons
○Makoto Saito1(1. RIKEN Pioneering Research Institute)
[1AS-02-06]Chasing the jumping genes
○Zhao Zhang1(1. Duke University)
[1PS-02-01]Mitochondrial fatty acid oxidation sets the species-specific timescale of temporal patterning in the developing cerebral cortex
○Ryohei Iwata1(1. VIB-KU Leuven)
[1PS-02-02]Uncovering Intrinsic Regulators of Human Neuronal Maturation via Transcriptomic Profiling and CRISPR-Based Functional Screens
○Leila Boubakar1, Ryohei Iwata1, Emir Erkol1, Pierre Vanderhaeghen1(1. VIB-KU Leuven – Center for Brain and Disease Research)
[1PS-02-03]Integrated ERK/PKA-YAP/TAZ-SHH signaling drives cortical evolutionary expansion and lineage diversification
○Zhengang YANG1(1. Institutes of Brain Science, Fudan University, Shanghai, China)
[1PS-02-04]The role of cerebrospinal fluid in coordinating neural stem cell proliferation and cortical expansion
○Jun Hatakeyama1, Mami Akaike2, Haruka Sato1, Saya Okada1, Yuta Nakashima2, Kenji Shimamura1(1. IMEG Kumamoto Univ., 2. FAST Kumamoto Univ.)
[1PS-02-05]Magnitude Matters: Upregulated Gene Expression as a Driver of Human Brain Evolution
○Ikuo K. Suzuki1, Xuanhao D. Zhou1(1. The University of Tokyo)
[1AS-03-01]Physiological cell competition ensure multicellular robustness.
○Tohru Ishitani1(1. The University of Osaka)
[1AS-03-02(1P-568)]Is the Dpp/BMP morphogen scaling required for scaling of wing vein patterns in the Drosophila wing?
○Shinya Matsuda1, Kaoru Sugimura1(1. University of Tokyo)
[1AS-03-03(1P-674)]Additional perturbations of Notch signaling rescue synchronized oscillations in the Lfng-knockout segmentation clock
○Ayumi Goto1,2, Akihiro Isomura1, Ryoichiro Kageyama1(1. RIKEN, 2. Kyoto university)
[1AS-03-04]Toward Understanding Size Robustness in Somitogenesis
Using Human Organoids
○Marina Sanaki-Matsumiya1, Maria Costanzo2, Mitsuhiro Matsuda3, Nicola Gritti2, Vikas Trivedi2, Hiromi Yanagisawa1, Miki Ebisuya3(1. Tsukuba univ., 2. European Molecular Biology Laboratory (EMBL) Barcelona, 3. Physics of Life, TU Dresden)
[1AS-03-05]Elucidating the molecular mechanisms that robustly maintain the proportions of cell types in the intestinal epithelium using Iterative Indirect Immunofluorescence Imaging for cryosections (Cryo-4i)
○Yumi Konagaya1(1. RIKEN Center for Biosystems Dynamics Research (BDR))
[1AS-03-06]A novel regulation of nuclear proteostasis (protein homeostasis) by cell competition regulator Mahjong (VprBP/DCAF1)
○Naoka Shiratsuchi1, Sakurako Nozaki1, Tomoki Kyo1, Riku Egami2, Kei Kozawa1, Yasuyuki Fujita1(1. Department of Molecular Oncology, Graduate School of Medicine, Kyoto University, 2. Department of Molecular Oncology, Institute for Genetic Medicine, Hokkaido University)
[1AS-03-07]Mechanisms that determine cellular fitness
○Tatsushi Igaki1(1. Grad. Sch. of Biostudies, Kyoto Univ.)
[1PS-03-01]The role of cellular senescence in the pathologies of age-related diseases
○Yohko Yoshida1,2, Tohru Minamino2(1. Juntendo University, Dept of Adv Senotherapeautics, 2. Juntendo University, Dept of Cardiovasc Biol and Med)
[1PS-03-02]Approaches to Age-Related Sleep Disorders via Senescent Cell Clearance
○Arisa Hirano1, Yasutaka Niwa2, Takeshi Sakurai1(1. University of Tsukuba, 2. Hirosaki University)
[1PS-03-03]Understand the mechanism underlying the cancer immunotherapy-associated adverse events: Findings from aged mice.
○Hirotake Tsukamoto1(1. Kyoto Univ.)
[1PS-03-04(1P-725)]Single-Cell Transcriptomic Analysis Reveals Aging-Associated Microglial Subpopulations, Their Dynamics, and Disease Relevance
○Hinase Moridono1,2, Ayaka Sugai1,3, Merve Bilgic1, Yukiko Gotoh3, Yusuke Kishi1,3(1. Institute for Quantitative Bioscience, 2. Faculty of Pharmaceutical Sciences, 3. Graduate school of Pharmaceutical Sciences)
[1PS-03-05(1P-706)]Involvement of innate immunity in age-dependent memory impairment in Drosophila
○Momoko Hoshi1, Akari Yuki2, Kotomi Onuki1, Aoi Yanagihara2, Motoyuki Itoh1, Ayako Tonoki1(1. Graduate School of Pharmaceutical Sciences, Chiba University, 2. Faculty of Pharmaceutical Sciences, Chiba University)
[1PS-03-06]Potential of Autonomic Nervous System Regulation in the Treatment of Kidney Diseases
○Tsuyoshi Inoue1(1. Nagasaki University)
[1PS-03-07(1P-508)]The mechanism of cellular senescence induction by lysosomal membrane damage
○Taiichi Osumi1,2, Takayuki Shima1,2, Makoto Horikawa1,2, Shuhei Nakamura1,2(1. Department of Biochemistry, Nara Medical University, 2. Center for Autophagy and Anti-Aging Research, Nara Medical University)
[1PS-03-08]Single-Cell Analysis of Endothelial Responses to Aging and Obesity Across Organs
○Masataka Yokoyama1, Akitoshi Nakayama1, Tomoaki Tanaka1(1. Chiba University Graduate School of Medicine)
[1AS-04-01]RNA Epicode metabolism regulates defense mechanisms
○Akiko Ogawa1(1. Graduate School of Pharmaceutical Sciences, Tohoku University)
[1AS-04-02]Cytoplasmic and extracellular functions of tRNA halves and their implications in diseases
○Yohei Kirino1(1. Thomas Jefferson University)
[1AS-04-03]Pathogenic mechanism of kidney failure upon dysfunction of a tRNA modification enzyme, CDKAL1
Hiroko Nagata1, Yu Nagayoshi1, ○Takeshi Chujo1, Hitomi Kaneko1, Kayo Nishiguchi1, Yutaka Kakizoe1, Hiroko Ijima1, Korin Sakakida1, Takeshi Masuda1, Sumio Ohtsuki1, Fan-Yan Wei2, Yukie Takahashi1, Takaichi Fukuda1, Hideaki Jinnouchi3, Ryosuke Yamamura1, Koki Matsushita1, Masataka Adachi1, Hideki Yokoi1, Kimitoshi Nakamura1, Hitoshi Nakazato1, Kazuhito Tomizawa1(1. Kumamoto Uni., 2. Tohoku Univ., 3. Jinnouchi Hospital)
[1AS-04-04]Discovery and Functional Characterization of Novel tRNA Methyltransferases in Higher Eukaryotes
○Shinichiro Akichika1, Akira Mineo1, Mariangela Spagnuolo2, Vishwaja Jhaveri3, Keita Miyoshi4,5, Shunya Kaneko4,5, Shintaro Iwasaki6,7, Takeo Suzuki1,8, Kuniaki Saito4,5, Jean-Yves Roignant2,3, Tsutomu Suzuki1(1. Dept. of Chembio., Grad. Sch. of Eng., Univ. of Tokyo, 2. Inst. of Pharm. and Biomed. Sci., JGU Mainz, 3. Center for Int. Gen., Facl. of Biol. and Med., Univ. of Lauassnne, 4. Invertebrate Genetics Lab., Nat. Inst. of Genetics, ROIS, 5. Dept. of Genetics, SOKENDAI, 6. RIKEN CPR, 7. Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 8. Present address: Dept. of Med. Biochem., Grad. Sch. of Med., Univ. of the Ryukyus)
[1AS-04-05(1P-181)]Biogenesis mechanism and significance of intronic polycistronic H/ACA snoRNAs in Drosophila melanogaster
○Mitsunaga Hamashima1, Tomohiro Yamano1, Shigeki Hirakata1, Takashi Fukaya2, Mikiko C. Siomi1(1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)
[1AS-04-06]Noncanonical Translation of the AUA Codon in Lactobacillus casei
○Chie Tomikawa1, Satoshi Okura1, Gakuto Uesugi1, Kazuyuki Takai1(1. Graduate School of Science and Engineering, Ehime University)
[1AS-04-07]Disruption of the tRNA epicode triggers degradation: Molecular mechanisms and cell-specific sensitivity
Keita Miyoshi1,2, Kiito Otsubo1,2, Shunya Kaneko1, Makoto Terauchi3, Yuki Hatoyama4, Hideki Noguchi3, Masato T Kanemaki2,4,5, ○Kuniaki Saito1,2(1. Inverte Genet Lab, Dept of Chr Sci, Natl Inst Genet, ROIS, 2. SOKENDAI, 3. ROIS-DS, 4. Mol Cell Engineering Lab, Dept of Chr Sci, Natl Inst Genet, , ROIS, 5. Dept Biol Sci, Grad Sch Sci, Univ Tokyo)
[1AS-04-08]Development of Gene Expression Control Technology through Functional Enhancement of Triplex-Forming Oligonucleotide
○Yu Mikame1, Asako Yamayoshi1(1. Institute of Science Tokyo)
[1PS-04-01]Practical and Realistic Results of knock-in mice generation by zygote genome editing with CRISPR-Cas9.
○Natsuki Mikami1,2, Hayate Suzuki2, Yoko Tanimoto2, Kanako Kato2, Miyuki Ishida2, Natsumi Iki2, Hiromi Sakata2, Yoshikazu Hasegawa2, Daitoku Yoko2, Megumi Takemura2, Satoru Takahashi2, Seiya Mizuno2(1. Ph.D Program in Human Biology, University of Tsukuba, 2. Laboratory of Animal Resource Center, University of Tsukuba)
[1PS-04-02(1P-066)]Activation of non-canonical DSB repair pathways acceralate CRISPR-Cas9 mediated HDR
○Shogo Yamamoto1, Shoma Takashima2, Daisuke Motooka3, Daisuke Tachibana1, Junpei Yamamoto2, Shigenori Iwai2, Keiichiro Suzuki1,2,4(1. Grad. Front. Bio., UOsaka, 2. Grad. Eng. Sci., UOsaka, 3. Res. Ins. Micro. Dis., UOsaka, 4. Ins. Ad. Co-cre. Stu., UOsaka)
[1PS-04-03]Super Ultra Great Delicious Wonderful Knock-In in Pigs: The Cutting Edge of High-Efficiency Knock-In via In Vitro Fertilized Embryos
○Arata Honda1(1. Jichi Medical University)
[1PS-04-04(1P-016)]Development and optimization of gene knock-in technology with the elimination of a large genomic fragment using CRISPR-Cas3 in human cultured cells
○Daiki Nagatomo1,2,3, Yusuke Kojima3, Kazuto Yoshimi4, Tomoji Mashimo4, Akitsu Hotta3, Tetsushi Sakuma2(1. Grad. Sch. Med., Kyoto Univ., 2. Grad. Sch. Agri., Kyoto Univ., 3. CiRA, Kyoto Univ., 4. Div. Animal Genet., Lab. Animal Res. Fac., Inst. of Med. Sci., Univ. of Tokyo)
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