Session Details
[1P-1]Poster Presentation
Wed. Nov 27, 2024 12:55 PM - 2:55 PM JST
Wed. Nov 27, 2024 3:55 AM - 5:55 AM UTC
Wed. Nov 27, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 1 (Marine Messe Fukuoka Hall A, 1F)
1.Molecular-a.Genome/Gene/Nucleic Acid
- b.DNA replication
- c.Recombination/Mutation/Repair
- d.Epigenetics/Chromatin
- e.Transcription
- f.RNA/Ribonucleoprotein
- g.Translation
- h.Protein
- i.Carbohydrate/Lipid/Metabolite
- j.Molecular Evolution/Comparative Genomics
- k.Cell-free Science
- l.Others
2.Cell
- a.Chromosome/Nuclear Body
- b.Phase Separation
- c.Protein Processing/Transport/Localization
- d.Cytoplasmic Membranous Organelle
- e.Cell Adhesion/Cell Motility/Extracellular Matrix
- f.Cell Membrane/Cytoskeleton
- g.Cell Proliferation/Division/Cell Cycle
- h.Signal Transduction (Post Translational Modification)
- i.Signal Transduction (Bioactive Substance)
- j.Cell Death
- k.Others
- b.DNA replication
- c.Recombination/Mutation/Repair
- d.Epigenetics/Chromatin
- e.Transcription
- f.RNA/Ribonucleoprotein
- g.Translation
- h.Protein
- i.Carbohydrate/Lipid/Metabolite
- j.Molecular Evolution/Comparative Genomics
- k.Cell-free Science
- l.Others
2.Cell
- a.Chromosome/Nuclear Body
- b.Phase Separation
- c.Protein Processing/Transport/Localization
- d.Cytoplasmic Membranous Organelle
- e.Cell Adhesion/Cell Motility/Extracellular Matrix
- f.Cell Membrane/Cytoskeleton
- g.Cell Proliferation/Division/Cell Cycle
- h.Signal Transduction (Post Translational Modification)
- i.Signal Transduction (Bioactive Substance)
- j.Cell Death
- k.Others
[1P-001]Development of highly sensitive RT-PCR/RT-LAMP methods for ultratrace detection of viral RNA
○Shun-ichi Matsuura1, Tomoya Baba2, Nozomi Natsui1, Shiori Abe1, Aritomo Yamaguchi1 (1. Res. Inst. Chem. Proc. Technol., AIST, 2. NIG, ROIS)
[1P-002]Development of low-background metatranscriptome analysis method
○Yuh Shiwa1, Shun-ichi Matsuura2, Haruo Suzuki3, Tomoya Baba4 (1. Fac. Life Sci., Tokyo Univ. of Agric., 2. Res. Inst. Chem. Proc. Technol., AIST, 3. Environment & Info. Studies, Keio Univ., 4. NIG, ROIS)
[1P-003]Development of a method for detecting SARS-CoV-2 in aerosols
Jun Uetake1, Yuh Shiwa2, Shun-ichi Matsuura3, Masaaki Kitajima4, Takashi Abe5, ○Tomoya Baba6 (1. FRC, Hokkaido Univ., 2. Fac. Life Sci., Tokyo Univ. of Agric., 3. Res. Inst. Chem. Proc. Technol., AIST, 4. Grad. Sch. of Eng., Univ. Tokyo, 5. Grad. Sch. of Sci. and Tech., 6. NIG, ROIS)
[1P-004]Effects of codon optimization on protein expression and specific activity
○Shuhei Kamata1, Hirokazu Takahashi1, Yoshiko Okamura1 (1. Hiroshima Univ.)
[1P-005]The effect of poly(A) chain length on mRNA stability
○Takato Ishikawa1, Hirokazu Takahashi1, Yoshiko Okamura1 (1. Hiroshima University, Graduate School)
[1P-006]Highly efficient introduction of insulin-expressing plasmids into hepatocytes using a discharge plasma gene delivery system and measurement of the activity of extracellular secretion
○Takuya Saiki1, Tomoya Otsuka1, Satomi Ihara3, Susumu Satoh1,2, Masafumi Jinno1,2 (1. Ehime Univ. Faculty Of Engineering, 2. i-Gene Corp., 3. Pearl Kogyo Co.Jp)
[1P-007]Investigation of genome editing with CRISPR-Cas9 using the micro-discharge plasma gene transfection method.
○Tomoya Otsuka1, Takuya Saiki1, Susumu Satoh1,2, Masahumi Zinno1,2, Kiyomi Ihara3 (1. Ehime Univ. Faculty Of Engineering, 2. i-Gene Corp., 3. Pearl Kogyo Co.Jp)
[1P-008]Development of mass-processing method for medical applications using surface discharge gene introduction method
○Hiroki Sakamoto1, Yuta Kuroki1, Yoshihisa Ikeda1, Susumu Satoh1,2, Masafumi Jinno1,2 (1. Ehime Univ. Faculty Of Engineering, 2. i-Gene Corp.)
[1P-009]Investigation of the effect of voltage waveform on transfection factor ROS in surface discharge gene transfection method
○Kenta Otsuki1, Yuta Kuroki1, Yoshihisa Ikeda1, Susumu Satoh1,2, Masafumi Jinno1,2 (1. Ehime Univ. Faculty Of Engineering, 2. i-Gene Corp.)
[1P-010]The discharge-plasma-generated reactive species affect gene expression in plasma gene transfection.
○Fumiya Ebisumori1, Masaki Yamashita1, Ryosuke Fukuda1, Yoshihisa Ikeda1, Susumu Satoh1,2, Masafumi Jinno1,2 (1. Ehime Univ. Faculty Of Engineering, 2. i-Gene Corp.)
[1P-011]Precise deletion by dual Cas12a cleavage in muscular dystrophy patient-derived iPS cells
○Kanata Imamura1,2, Gou Takahashi1,3, Yuichiro Miyaoka1,2,4 (1. Regenerative Medicine Project, TMIMS, 2. Grad. Sch. Med and Dent Sci., TMDU, 3. Dep of Anim Sci. Fac of Agri., Tokyo Univ of Agri, 4. Grad. Sch. Hum Sci., Ochanomizu Univ)
[1P-012]Development of bacterial semi-bulk RNA-seq technology for comprehensive and time-resolved expression dynamics analysis of bacterial populations
○Mika Nishimura1,2, Kaori Aikawa3, Tetsutaro Hayashi4, Mariko Kuse4, Itoshi Nikaido4,5, Haruko Takeyama1,2,3,6, Masahito Hosokawa1,2,3,6 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. CBBD-OIL, AIST-Waseda Univ., 3. Res. Org. Nano Life Innov., Waseda Univ., 4. RIKEN BDR, 5. Med. Res. Inst., Tokyo Med. and Dent. Univ., 6. Inst. Adv. Res. Biosyst. Dynam., Waseda Res. Inst. Sci. Eng., Waseda Univ.)
[1P-013]Development of a high-precision CRISPR knock-in method through comparative analysis of DNA double-strand break repair pathways
○Chiharu Teoi1, Shoji Hata1, Akira Mabuchi1, Atsushi Toyoda2, Daiju Kitagawa1 (1. Laboratory of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, The University of Tokyo, 2. Comparative Genomics Laboratory, National Institute of Genetics)
[1P-014(1AS-16-03)]Horizontal genome transfer from red algae to mammalian cells
○Ryota Aoki1, Tomoko Matsunaga1, Hidenori Nishihara2, Tae Kuramoto2, Takuya Sakamoto3, Yuko Sato4, Hiroshi Kimura5, Sachihiro Matsunaga1 (1. Dept. of Integr. Biosci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Dept. Adv. Biosci., Grad. Sch. Agr., Kindai Univ., 3. Dept. of Sci., Fac. of Sci., Kanagawa Univ., 4. Med. Inst. Bioreg., Kyushu Univ., 5. Inst. of Innov. Res., Tokyo Inst. of Tech.)
[1P-015]Understanding the Gene Set Required for Heterotrophy and Autotrophy Switching in Hydrogen-Oxidizing Bacteria
○Shota Yamazaki1, Yasunori Aizawa1,2 (1. School of Life Science and Technology, Science Tokyo, 2. Kanagawa Institute of Industrial Science and Technology (KISTEC))
[1P-016(1AS-12-03)]Differential DNA methylation controls asynchronous DNA replication at imprinted chromosomal domains
○Yui IMAIZUMI1, François Charon3, Benoît Moindrot3, Daan Noordermeer3, Jean-Charles Cadoret4, Robert Feil1,2 (1. Institut de Génétique Moléculaire de Montpellier, 2. University of Montpellier, 3. University of Paris-Saclay, 4. Institut Jacques Monod)
[1P-017(1AS-02-04)]R-loop regulation by RNA-dependent RNA polymerase activity
○Mitsuhiro Machitani1, Akira Nomura1,2, Kenkichi Masutomi1 (1. Div. Cancer Stem Cell, Natl. Cancer Ctr. Res. Inst., 2. Dep. Orthopedic Surg., Tokai Univ. Sch. Med.)
[1P-018]RNA binding protein Puf5 and HMGB protein Ixr1 contribute to the DNA replication stress response.
○Megumi Sato1, Kenji Irie1 (1. Department of Molecular Cell Biology, Institute of Medicine, University of Tsukuba)
[1P-019]Development of a recombinase polymerase amplification combined with lateral flow immunoassay for rapid detection of Salmonella. in blood culture samples
○Arpasiri Srisrattakarn1, Aroonwadee Chanawong1, Nicha Charoensri1, Patcharaporn Tippayawat1, Bhanubong Saiboonjan2, Praew Kotruchin3, Pariwat Phungoen3, Orapan Sripichai4, Jenjira Charoem4, Aroonlug Lulitanond1 (1. Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand, 2. Center for Innovation and Standard for Medical Technology and Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand, 3. Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand, 4. National Institute of Health (NIH), Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand)
[1P-020(1AS-16-05)]Genome assembly and pathway visualization system for enhanced production of specialized metabolites in red perilla (Perilla frutescens)
○Keita Tamura1, Naoya Oec2, Ryo Nozu1,3, Hidemasa Bono1,3 (1. Genome Editing Innovation Center, Hiroshima Univ., 2. Dogrun Inc., 3. Grad. Sch. Integ. Sci. Life, Hiroshima Univ.)
[1P-021]Effect of polyethylenimine on DNA the higher-order structure of DNA and gene activity
○Miko Sato1, Kosuke Imanaka1, Yuko Yoshikawa1, Kenichi Yoshikawa1, Takahiro Kenmotsu1 (1. Doshisha Univ.)
[1P-022]Identification of E.coli chromosommal genes that promote horizontal gene transfer from E.coli (prokaryote) to yeast (eukaryote) (2)
Kazuyuki Nakamura1, Yudai Takahashi1, Yuya Inoue2, Fatin Iffah Rasyiqah Mohamad Zoolkefli1, Katsunori Suzuki1, ○Kazuki Moriguchi1 (1. Hiroshima University, 2. National Museum of Nature and Science)
[1P-023]Analysis of genome conformation induced transcriptional fluctuations caused by feline endogenous retroviruses
○Rikuto Goto1, Naoaki Sakamoto1, Akinori Awazu1 (1. Hiroshima University)
[1P-024]Abiotic Stress Resilience in CaMBD-Truncated OsGAD1 and OsGAD3 Rice Lines: Insights from RNA-Seq Analysis
○Ummey Kulsum1, Kazuhito Akama1 (1. Graduate school of Natural Science and Technology, Shimane University,)
[1P-025]Photochemical internalization for intracellular mRNA delivery
○Hayaki Maemoto1, Kazunori Watanabe1, Mari Takahara1, Keiji Itaka2, Takashi Ohtsuki1 (1. Grad. Sch. of Interdis. Sci. and Eng. in Health Sys., Okayama Univ., 2. Center for Infectious Disease Education and Research, Osaka Univ.)
[1P-026]Screening for factors resolving DNA entanglement in Schizosaccharomyces pombe
○Tetsushi Iida1, Takako Sugaya1, Kyoko Torigoe1, Yoshihiro Miwa1 (1. RIKEN BRC)
[1P-027]Identification of intracellular pH regulation genes in Bacillus subtilis by using Colony Live System
○Takeru Kurakawa1, Hiroko Fukuda1, Hirotada Mori2, Mikio Nakajima3, Masakazu Kataoka1 (1. Shinshu Univ., 2. Guangdong Acad. Agr. Sci., ,China, 3. MSL Corp)
[1P-028(1AS-11-05)]Shin-RamDA-seq: A high-sensitivity approach for single-cell transcriptomic analysis and precise detection of genomic structural variants
○Tetsutaro Hayashi1, Mariko Kuse1, Haruka Ozaki2, Mika Yoshimura1, Tempei Sato1, Kenzui Taniue3, Nobuyoshi Akimitsu3, Itoshi Nikaido1 (1. RIKEN, 2. Univ. of Tsukuba, 3. Univ. of Tokyo)
[1P-029]Diversity and Evolution of RNA Phages in the Human Gut Microbiome Through Metagenomic and Metatranscriptomic Sequencing
○Ryota Sugimoto1, Luca Nishimura2, Ituro Inoue3 (1. Toyama Pref. Univ., 2. Inst. of Med. Sci., Univ. of Tokyo, 3. Natl. Inst. of Genetics)
[1P-030]Discovery and generation of polymorphic copy number variants in human induced Pluripotent Stem Cells (iPSCs)
○Gabriel Martínez-Gálvez1, Xiaoyan Ren1,2, Tomoko Matsumoto1, Megumu K Saito1, Knut Woltjen1 (1. Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan, 2. Graduate School of Medicine, Kyoto University, Japan)
[1P-031]Identification and functional analysis of a novel RNA-binding protein that is important for embryonic cardiac development
○Jun Koyama1, Natsuki Mikami2, Kazuya Murata3, Seiya Mizuno4 (1. Master’s Program in Medical Science, University of Tsukuba, 2. Ph.D Program in Human Biology, University of Tsukuba, 3. COMIT, Institute for Advanced Study, Gifu University, 4. Institute of Medicine, University of Tsukuba)
[1P-032]Comprehensive genomic insights into the sucrose utilization and levan biosynthesis pathways of P. koreensis HL12: novel fructooligosaccharides and levan producing bacteria
○Hataikarn Lekakarn1, Daran Prongjit1, Benjarat Bunterngsook 2, Wuttichai Mhuantong2 (1. Thammasat University, 2. National Center for Genetic Engineering and Biotechnology)
[1P-033(1AS-16-04)]Toward understanding the mechanism of fruit shape diversity in hexaploid persimmon cultivars by GWAS.
○Ayano Horiuchi1,2, Noriyuki Onoue3, Mai Minamikawa4, Kazusa Nishimura2, Kenta Shirasawa5, Yasutaka Kubo2, Koichiro Ushijima2, Takashi Akagi2 (1. Chiba Univ., 2. Okayama Univ., 3. Inst. Fruit Tree and Tea Sci., NARO, 4. Chiba Univ., IAAR, 5. Kazusa DNA Res. Inst.)
[1P-034]The Paf1 complex maintains rDNA stability through a novel mechanism.
○zijun zhong1, masaki Yokoyama2, takehiko Kobayasi1,3 (1. Kobayashi Lab, Institute For Quantitative Bioscience, The University of Tokyo, 2. Division of Cancer and Senescence Biology, Cancer Research Institute, Kanazawa University , 3. Department of Biological science, The Graduate School of of Science, University of Tokyo)
[1P-035]Distribution Analysis of Ionizable Lipids from LNPs and Their Metabolites in Mouse Liver Using MS Imaging
○Kaoru Nakagawa1, Keiko Kajiwara2, Sachiko Sakamoto2, Qiuyi Wang1, Ayako Matsunawa2, Hiroyuki Tanaka2, Masayuki Sugimoto2, Hirofumi Ebe2, Kenjiro Minomi2, Manami Kobayashi1, Naoki Morita1, Tadayuki Yamaguchi1, Junko Iida1 (1. Shimadzu Corporation, 2. Nitto Denko Corporation)
[1P-036]Genetic comparison analysis of nucleic acids extracted from the tumor and non-tumor tissue by a freeze-crush method
○Yuichi Tokuda1, Hiroaki Oku2, Tomomichi Nakayama2, Akihide Watanabe2, Chie Sotozono2, Kei Tashiro1, Masakazu Nakano1 (1. Dept. of Gen. Med. Sci., Kyoto Pref. Univ. of Med., 2. Dept. of Ophthal., Kyoto Pref. Univ. of Med.)
[1P-037(1PS-16-06)]Accelerated laboratory evolution of bacterial genome structures via transposon activation
○Yuki Kanai1, Atsushi Shibai2, Naomi Yokoi2, Saburo Tsuru3, Chikara Furusawa2,3 (1. Biological Sciences, The University of Tokyo, 2. BDR, RIKEN, 3. UBI, The University of Tokyo)
[1P-038]Genetic Insights into the Unique Visual System of the Jumping Spider, Carrhotus xanthogramma
○Kaoru Ogino1,2, Koh Nakagawa1,3,4, Nobuaki Kono1,2,3 (1. Institute for Advanced Biosciences, Keio University , 2. Faculty of Environment and Information Studies, Keio University, 3. Graduate School of Media and Governance, Keio University , 4. JT Biohistory Research Hall)
[1P-039]Estimation of leaf fall disease-related genes by comparative genomic analysis of Hevea brasiliensis
○Taisei Omote1, Fetrina Oktavia2, Tomoko Kuriyama3, Masaharu Kawauchi3, Minami Matsumi3, Yuko Makita3,1 (1. Maebashi Institute of Technology, 2. IRRI, 3. RIKEN CSRS)
[1P-040]Development of Nucleic Acid-Peptide Droplets-Targeting Drug Delivery Technology using Cell Nuclear Nanotransporter
○Haruka Taniguchi1, Mitsuki Tsuruta2, Soma Kawashima2, Daisuke Miyoshi1, Koji Nagahama1 (1. Konan University, 2. Graduate School of FIRST, Konan University)
[1P-041(1PS-16-08)]Strengthening the robustness of Candida tropicalis TBRC 1245 through adaptive laboratory evolution approach to increase the xylitol production efficiency
○Benjarat Bunterngsook1, Katesuda Aiewviriyasakul1, Hataikarn Lekakarn2, Wuttichai Mhuantong1, Verawat Champreda1 (1. National Center for Genetic Engineering and Biotechnology, 2. Thammasat University)
[1P-042]A screening method for essential genomic regions in human X chromosome
○Taichi Akase1,2, Hikaru Kurasawa3, Hinata Hashimoto1, Yuta Matsuura1, Shota Yamazaki1, Shinya Kaneko1, Tomoyuki Ohno4, Yasunori Aizawa1,3,4 (1. Sch. Life Sci. Technol., Institute of Science Tokyo, 2. IMS, Riken, 3. KISTEC, 4. Logomix, Inc.)
[1P-043]Examination of the regulatory role of intronic retrotransposon Alus in the parental gene transcription.
○Ayumu Yamamoto1, Tomoyuki Ohno4, Taichi Akase1,2, Yasunori Aizawa1,3,4 (1. Science Tokyo, 2. RIKEN・IMS, 3. KISTEC, 4. Logomix)
[1P-044]Bacteria genome rewriting by the developed genome editing HoSeI method
○Riho Hirano1, Miho Yoshimura3, Kaneyoshi Yamamoto1,2,3 (1. Hosei University Graduate School of Science and Engineering, 2. Hosei University Faculty of Bioscience and Applied Chemistry, 3. Hosei University Research Center for Micro-Nano Technology)
[1P-045]Functional analysis of nucleoid proteins, Hha and YdgT, in Escherichia coli
○Taku Oshima1 (1. Toyama prefectural university)
[1P-046]Functional Annotation Workflow for Novel Model Organisms
○Hidemasa Bono1,2 (1. Grad. Sch. of Integ. Sci., Hiroshima Univ., 2. Hiroshima Univ. Genome Edit. Innov. Ctr)
[1P-047]HiDy-CE: High Dynamic Range Capillary Electrophoresis Method for Sensitive Detection of Low-frequency Driver Mutations
○Nobue Tamamura1, Yoshihiko Hagiwara2, Hirokazu Kato2, Yusuke Ono3, Yusuke Mizukami1 (1. Asahikawa Medical University, 2. Hitachi High-Tech Corporation, 3. Sapporo-Higashi Tokushukai Hospital)
[1P-048]Study on the long-term adaptation to high temperature using a model cyanobacterium.
○Yu Kanesaki1 (1. Shizuoka University)
[1P-049]NOLC1 regulates ligand-dependent PXR nuclear translocation and its function
○Kyoka Nagaoka1, Masataka Nakano1,2, Kiamu Kurosawa1, Yuichiro Higuchi3, Shotaro Uehara3, Nao Yoneda3, Tatsuki Fukami1,2, Hiroshi Suemizu3, Miki Nakajima1,2 (1. Facult. of Pharm. Sci., Kanazawa Univ., 2. WPI-NanoLSI, Kanazawa Univ., 3. Central Institute for Experimental Medicine and Life Science)
[1P-050]Whole genome analysis of Saitoella coloradoensis and Savitreella phatthalungensis in the subphylum Taphrinomycotina (Fungi)
○Yuuki Kobayashi1, Keita Aoki1, Yuh Shiwa2, Junta Sugiyama3,4, Naoto Tanaka2, Masako Takashima1 (1. Res. Ins. Agr. Life Sci., Tokyo Univ. Agr., 2. Fac. Life Sci., Tokyo Univ. Agr., 3. TechnoSuruga Laboratory Co., Ltd., 4. National Museum of Nature and Science)
[1P-051]An Ultra-Efficient Scalable Pipeline for Ancient DNA Analysis
○Koji Ishiya1 (1. Sapiens Life Sciences Evolution and Medicine Research Center, Kanazawa University)
[1P-052]Realization of Absolute Quantitative 16S rRNA NGS Analysis Using Spike-In Synthetic DNA Standard
○Yuto Kitajima1, Tomoya Uchiyama1, Yasunobu Terabayashi1, Yoshitaka Kimura1 (1. TAKARA BIO INC.)
[1P-053]Development of gRNA sequence design method for "UCAY", a novel genome editing technology
○Nagi Yoshitsugu1, Yasuhiro Moriizumi2, So Makabe2, Yuichi Kobashi2 (1. Tokyo Metropolitan Industrial Technology Research Institute, 2. BEX CO., LTD.)
[1P-054]Regulation of triplex structure formation by N6-methyladenine modification
○Ryuga Kubota1, Mikoto Chishima, Wataru Yoshida1 (1. Tokyo Univ. of Tech.)
[1P-055]The establishment of cell lines to monitor epithelial-mesenchymal transition
○Rin Fukumoto1, Kaya Osanai2, Konoka Nakamura2, Toshihiko Kishimoto2, Kenji Kokura2 (1. Toho graduate school, 2. Toho Univ.)
[1P-056]Analysis of the molecular mechanism of MCM activation by DDK using an in vitro reconstitution system
○Yugo Zaizen1, Kaname Saito1, Miyako Shiraishi1, Yoko Katsuki1, Yasunori Noguchi1, Masatoshi Fujita1 (1. Kyushu University)
[1P-057]Mechanism of chromatin structure changes induced by Cdt1
○Ryotaro Mori1, Kana Sakai1, Saki Tsujita1, Yasunori Noguchi1, Youko Katsuki1, Miyako Shiraishi1, Masatoshi Fujita1 (1. Kyushu Univ.)
[1P-058]Automated detection of DNA fibers using Mask-RCNN
○Takuma Yamato1, Kiyoshi Nishikawa1, Kan Okubo1, Takuya Abe2 (1. Tokyo Metropolitan Univ., 2. Tohoku Medical and Pharmaceutical Univ.)
[1P-059]Biochemical analysis of the replicative DnaB-DciA helicase loading system in the eubacterium Caulobacter crescentus.
○Keito Watanabe1, Shogo Ozaki1, Tsutomu Katayama1 (1. Kyushu University)
[1P-060(1AS-15-02)]Glucose metabolism-coordinated regulation of DNA bending factor IHF for ensuring timely replication initiation
○Mizuki Yoshida1, Rion Satomura1, Kazutoshi Kasho1, Tsutomu Katayama1 (1. Kyushu Univ.)
[1P-061]Search for dissociation factor of DNA bending protein IHF which is crucial for regulating replication initiation
○Sho Nakazono1, kazutoshi Kasho1, tsutimu Katayama1 (1. Kyushu university)
[1P-062(1AS-12-04)]Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10
○Masateru Takahashi1, Yujing Ouyang1, Amani Al-Amodi1, Muhammad Tehseen1, Lubna Alhudhali1, Afnan Shirbini1, Vlad-Stefan Raducanu1, Gang Yi1, Ammar Usman Danazumi1, Alfredo De Biasio1, Samir M Hamdan1 (1. King Abdullah University of Science and Technology)
[1P-063]Investigation of DNA double-strand break repair defects following low level of intracellular ATP
○Ryota Hayashi1, Hikaru Okumura1, Mayu Isono1, Motohiro Yamauchi2, Daiki Unami1, Masamichi Yamamoto3, Yuki Uchihara1, Atsushi Shibata1 (1. Keio Univ., 2. Kyusyu Univ., 3. NCVC)
[1P-064]Elucidating the mechanism of the recruitment of SLX4 in the replication stress response induced by lacO-LacI interaction on a human chromosome
○Takuma Okano1, Jumpei Fujii1, Tomoki Matsumura1, Kazumasa Yoshida1, Miyako Shiraishi1, Yasunori Noguchi1, Yoko Katsuki1, Masatoshi Fujita1 (1. Kyushu Univ.)
[1P-065]Efficient generation of foreign gene-free knockout cell line using episomal TiD-X
○Satoshi Kurihara1, Naoki Wada2, Kazuya Marui2, Emi Murakami2, Yuriko Osakabe3, Keishi Osakabe2 (1. Grad.Sch. of Sci. & Tech Ind., Tokushima Univ, 2. Grad. Sch. of Tech., Ind. & Soc., Tokushima, 3. Sch. Life Sci. & Tech, Science Tokyo)
[1P-066]The knockdown effects of abasic site-processing enzymes and mismatch repair-related proteins on the action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine
○Ruriko Fukushima1, Tetsuya Suzuki1, Hiroyuki Kamiya1 (1. Hiroshima Univ.)
[1P-067]DNA synthesis promoted by MCM8/9 helicase is controlled by the recombination factor, FIRRM
○Yuto Takahashi1, Daichi Nishiguchi2, Tatsuro Takahashi2, Masato Kanemaki1,3,4 (1. Natl. Inst. of Genetics, 2. Kyushu Univ. Grad. Sch. of Biol. Sci., 3. Sokendai Grad. Sch. of Adv. Sci. Genetics, 4. Tokyo Univ. Grad. Sch. of Biol. Sci.)
[1P-068(1AS-02-02)]When Base Excision Repair goes wrong - Chromosome fragmentation due to TORC2 inhibition depends on nuclear actin-dependent remodeler activity
○Susan M Gasser1, Kenji Shimada2, Verena Hurst2, Christian B Gerhold2, Cleo V.D. Tarashev2, Masahiko Harata3, Barbara van Loon4 (1. ISREC Foundation and University of Lausanne, 2. FMI, Basel, 3. Tohoku University, Sendai, 4. Norwegian University of Science and Technology)
[1P-069]Development of visualization technique for dynamic change in resolution of homologous recombination intermediate
○Yusaku Hamada1, Masataka Tsuda1,2 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. Division of Genome Safety Science, National Institute of Health Sciences)
[1P-070]Application of the nickase Cas9-based allele-specicic genome editing method "MILD" to DM1 and development of its delivery method
○Yusuke Kojima1, Yumi Tsubokura1, Yoshie Masuda1, Shinichiro Nakada2,3, Akitsu Hotta1 (1. Kyoto Univ., 2. Osaka Univ., 3. Kyoto Pref. Univ. of Med.)
[1P-071]The Shuttle Vector (SV)-NGS analysis enables the discussion of action-at-a-distance mutations induced by oxidative DNA damage in custom-designed mutation analysis libraries
○Chiho Fujiwara1, Hidehiko Kawai1,2, Hiroyuki Kamiya1,2 (1. Sch. Pharm. Sci., Hiroshima Univ., 2. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ.)
[1P-072(1AS-11-07)]Regulation of γH2AX domain expansion in DNA damage response
○Kyoichi Isono1, Ryo Onishi2, Yaoi Kimura3, Junichiro Takano2, Koyama Momo1, Haruhiko Koseki2 (1. Wakayama Med Univ, 2. RIKEN IMS, 3. Yokohama City Univ)
[1P-073]Competitive interactions of Rad17 KYxxL motif and Rhino to the 9-1-1 complex in the activation of the ATR-Chk1 pathway
○Yasunori Fukumoto1, Ryuzaburo Yuki2, Yuji Nakayama2, Yasumitsu Ogra1 (1. Graduate School of Pharmaceutical Sciences, Chiba University, 2. Kyoto Pharmaceutical University)
[1P-074(1AS-11-03)]Visualization of the native nucleosome containing the histone variant H2A.X
○Haotong Zhuang1,2, Suguru Hatazawa1, Cheng-han Ho1, Yoshimasa Takizawa1,2, Hitoshi Kurumizaka1 (1. Institute for Quantitative Biosciences, The University of Tokyo, Japan, 2. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Japan)
[1P-075]Influence of DNA repair of Amino acid-residues required for Rad51-Rad51 binding in S. cerevisiae
○Kaiu Ukita1, Naoto Arai1,2 (1. Appl. Life Sci. Grad. Sch. of Biores. Scie., Nihon Univ., 2. Dpt. of Biosci. Coll. of Biores. Sci. Nihon Univ.)
[1P-076]Evaluating the relationship between rDNA instability and aging through Systems Biology approaches
○Itamar Jose Guimaraes Nunes1,2, Takehiko Kobayashi2 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)
[1P-077]Accumulation of APOBEC3B in R-loop structure after DNA damage
○Yohei Saito1, Yumi Yamamoto1, Fumihiko Yamamoto1 (1. Tohoku Med. and Pharm. Univ.)
[1P-078(1PS-06-02)]Repair of topoisomerase 1–induced DNA damage by TDP2
○Masataka Tsuda1,2, Naoto Shimizu1,2, Yusaku Hamada1,2, Kazuki Izawa1 (1. National Institute of Health Sciences, 2. Hiroshima University)
[1P-079]Analyzing chromatin dynamics of damaged ribosomal RNA gene during its repair in Saccharomyces cerevisiae
○Mina Iwaki1, Masahiko Harata1, Chihiro Horigome1 (1. Tohoku University Graduate School of Agricultural Science)
[1P-080]Establishment of transformation and genome editing methods in a novel acid-tolerant lactic acid bacterium Lactiplantibacillus plantarum
○Reo Sugiura1, Moeka Higurasi1, Takayuki Arazoe1, Takasi Kamakura1 (1. Tokyo University of Science)
[1P-081(1AS-12-08)]Rad54 prevents excessive intergenerational Rad51 aggregation in fission yeast
Goki Taniguchi1, Alexander I May1, Hiroshi Iwasaki1, ○Hideo Tsubouchi1 (1. Tokyo Institute of Technology)
[1P-082]Analysis of radiation-induced DNA double-strand break repair in the presence of inflammatory cytokines.
○Mayu Isono1, Ryota Hayashi1, Shunji Haruna1,2, Misaki Hatakeyama1, Ken Okuda1, Kohei Tateno1,3, Yuki Uchihara1, Akiko Takahashi2, Atsushi Shibata1 (1. Dept. of Mol. Oncol. Pharm., Keio Univ. Fac. of Pharm., 2. Div. of Cell. senescence, The Cancer Inst., JFCR, 3. Dept. of Gen. Surg. Sci., Gastroenterol. Surg., Gunma Univ., Grad. Sch. of Med.)
[1P-083(1MS-09-05)]Revolutionizing molecular biology experiments with laboratory automation
○Kensuke Otsuka1, Yuki Fujimichi1, Yuki Yaguchi2, Tomoko Ueno2, Daiki Unami2, Hikaru Okumura2, Atsushi Shibata2 (1. Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry, 2. Keio University Faculty of Pharmacy)
[1P-084]Liquid-liquid phase separation by human RAD52 and its impact on DNA double-strand break repair mechanisms
○JUNHONG WU1, Chiaki Kinosita1, Takeshi Yasuda2, Wataru Kagawa1 (1. Meisei University, 2. Institute for Quantum Life Science, QST)
[1P-086]PAM-relaxed Cas9 expands the targetable range of natural human deletion variants using microhomology-mediated gene editing in human iPSCs
○Kazusa Matsui1,2, Sayaka Kayumi1, Ryo Niwa1,2, Knut Woltjen1 (1. CiRA, Univ. Kyoto, 2. Grad. Sch. of Med., Univ. Kyoto)
[1P-087]Mechanistic analysis of nucleotide excision repair by isolation of various intermediate complexes using BioID technology
○Ryo Akahori1, Shunki Inoue1, Mao Naito1, Tomonori Matsuya1, Hidetaka Kosako2, Mituo Wakasugi1, Tsukasa Matsunaga1 (1. Kanazawa Univ., 2. Tokushima Univ.)
[1P-088]Human DNA ligase 1 facilitates LINE-1 rertrotransposition
○Ryuto Ohara1,2, Shintaro Adachi1,2,4, Watanabe Yuzo3, Fuyuki Ishikawa1,4, Tomoichiro Miyoshi2,1,4 (1. Kyoto Univ., 2. RIKEN IMS, 3. Proteomics, Grad. Sch. of Bio., Kyoto Univ., 4. RBC, Grad. Sch. of Bio., Kyoto Univ.)
[1P-089]Mechanism of Interhomolog homologous recombination induced by multiple nicks
○AKIKO TOMITA1, HIROYUKI SASANUMA3, YUKA NAKAZAWA2, MAYUKO SHIMADA2, TOMOO OGI2, SHINICHIRO NAKADA1 (1. Kyoto Prefectural University of Medicine, 2. Research Institute Environmental Medicine Nagoya University, 3. Tokyo Metropolitan Institute of Medical Science)
[1P-090]Construction of auxin-inducible degron (AID) system for the Basidiomycetous yeast Naganishia liquefaciens.
○YUKI KATO1, HIDEO TSUBOUCHI 2, HIROSHI IWASAKI2 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. Institute of Innovative Research, Tokyo Institute of Technology)
[1P-091]Mechanistic Analysis of Long-Range Deletions Induced by Multiple DNA Nicks
○Yuya Namaki1,2, Akiko Tomita2, Hiroyuki Sasanuma3, Shinichiro Nakada2 (1. Graduate School of Medicine, Osaka University, 2. Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 3. Tokyo Metropolitan Institute of Medical Science)
[1P-092]H3K4 methyltransferase SETD1A drives G1/S cell cycle progression in gastric cancer cell via non-catalytic function
○Meng Ning1, Takayuki Hoshii1, Shintaro Izumi1, Tianhui Zhu1, Makoto Matsumoto1, Bahityar Rahmutulla1, Masaki Fukuyo1, Atsushi Kaneda1,2 (1. Department of Molecular Oncology, Graduate School of Medicine, Chiba University, 2. Health and Disease Omics Center, Chiba University)
[1P-093]Identification of oncogenic super enhancers and their target genes by genome-wide chromatin interaction analysis
○Qin Fan1, Atsushi Okabe1,2, Motoaki Seki1, Tianhui Zhu1, Masaki Fukuyo1, Bahityar Rahmutulla1, Atsushi Kaneda1,2 (1. Department of Molecular Oncology, Graduate School of Medical, Chiba University, 2. Health and Disease Omics Center, Chiba University)
[1P-094]The regulatory mechanism of histone sorbylation induced by preservative sorbic acid and its epigenetic regulation
○Kota Noritsugu1, Takehiro Suzuki2, Naoshi Dohmae2, Yoshito Kumagai3, Akihiro Ito1 (1. Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci. , 2. Biomolec. Character. Unit, RIKEN CSRS, 3. Grad. Sch. of Pharm. Sci.,Kyushu Univ.)
[1P-095(1PS-08-02)]Elucidation of the transcriptional regulatory mechanisms by single-cell multi-epigenomics
○Takeru Fujii1, Akihito Harada1, Kazumitsu Maehara1, Hiroshi Kimura2, Yasuyuki Ohkawa1 (1. Medical Institute of Bioregulation, Kyushu University, 2. Institute of Innovative Research, Tokyo Institute of Technology)
[1P-096(1AS-17-08)]Distinctive regulation of transposable elements in the human brain
○Risa Watanabe1, Cyril J Peter1, Bicheng Jiang1, Foramben Patel1, Travis Dawson1, Aman Agarwal1, Will Lounsbery-Scaife1, Maya Fridrihk1, Kiran Girdhar1, Panos Roussos1,2, Ashok Patowary3, Sathiji Nageshwaran3, Nadejda Tsankova1, Hyejung Won4, Robert Sebra1, Benjamin Chen1, Dan Hasson1, Schahram Akbarian1 (1. Icahn School of Medicine at Mount Sinai, 2. James J. Peters VA Medical Center, 3. University of California Los Angeles, 4. University of North Carolina at Chapel Hill)
[1P-097]Paternal Transgenerational Epigenetic Inheritance of Diabetes in Mice
○Beverly Ann Boyboy1, Tomoko Ichiyanagi1, Yamato Ohtsuka1, Hirohisa Nitta1, Kenji Ichiyanagi1 (1. Nagoya University)
[1P-098]A H3K36 methyltransferase-regulated salvaging pathway restores centromere integrity via CENP-A retargeting
○Ee Sin Chen1, Kim Kiat Lim1, Tsz-Fung Lam1 (1. National University of Singapore)
[1P-099]Cryo-EM structure of the ASH1L-nucleosome complex
○Cheng-Han Ho1, Yoshimasa Takizawa1, Kendra Vann2, Jiuyang Liu2, Tatiana Kutateladze2, Hitoshi Kurumizaka1 (1. IQB, The University of Tokyo, 2. Department of Pharmacology, University of Colorado School of Medicine)
[1P-100]Structural quantification of interacting neighboring nucleosomes in the setting of local chromatin compaction
○Satoru Ishihara1, Naoe Kotomura1, Yohei Shimono1, Kazutsune Yamagata1 (1. Fujita Health Univ. Sch. Med.)
[1P-101(1AS-17-03)]Role of transposable elements to link 3D genome organization with DNA replication timing
○SHARIF Jafar1, KOSEKI Haruhiko1 (1. IMS Yokohama RIKEN)
[1P-102]Phosphorylation and histone peptides reduce side- and main-chain dynamics of HP1 during phase separation, as studied by conventional and TOAC spin labels
○Isao Suetake1, Toshiki Takei4, Kazunobu Sato3, Tomoaki Sugishita4, Yuichi Mishima4, Makoto Miyata2, Toshimichi Fujiwara4, Yoh Matsuki4, Hironobu Hojo4, Toshiaki Arata2,4 (1. Nakamura gakuen Univ., 2. Dept. Biol., Grad. Sch. Sci., Osaka Met. Univ, 3. Dept. Chem., Grad. Sch. Sci., Osaka Met. Univ, 4. IPR, Osaka Univ)
[1P-103]Regulation and Analysis of Myristoylation in Histones
○Akio Nishimoto1, Yongwoon Han4, Takei Toshiki1, Ito Shun2, Shinndou Hideo3, Suetake Isao2 (1. Osaka University , 2. Nakamura Gakuen University, 3. National Center for Global Health and Medicine, 4. Institute of Physical and Chemical Research)
[1P-104]Contribution of G9a/GLP to histone H3K27 methylation in mouse cells
○Yuto Iwaya1,2, Ayumi Yamada1, Yoichi Shinkai1 (1. Shinkai Cellular Memory Laboratory, RIKEN, 2. Saitama University)
[1P-105]Elucidation of the molecular basis for rejuvenation of senescent cells by partial reprogramming
○Yuta Moriguchi1,2, Yasuhiro Nakano1,3, Soichirou Kumamoto1, Tomoaki Hishida4, Yoshikazu Johmura1,3 (1. Cancer Res. Inst. of Kanazawa Univ., 2. Sch. Biol. Sci. Tech., Col. Sci. Engr., Kanazawa Univ., 3. Inst. Front Sci. Initiative of Kanazawa Univ., 4. Sch. Pharm., Wakayama Med. Univ.)
[1P-106]Establishment of large H3K27me3 domains during neuronal maturation
○Natsumi Yamada1, Hiroki Sugishita2, Yukiko Gotoh1,2 (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2. The University of Tokyo International Research Center for Neurointelligence (WPI-IRCN))
[1P-107(1AS-17-04)]Sequence-specific anti-silencing mechanism regulated by transposon-derived protein VANC
○Akihisa Osakabe1, Yusaku Tanaka1, Raku Saito2, Hisato Hirano1, Wataru Shihoya1, Yuzuru Ito1, Osamu Nureki1, Tetsuji Kakutani1 (1. Biol. Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)
[1P-108]Investigation of the mechanism and significance of de novo Polycomb-dependent enhancers during organogenesis
○Kazunori Hojo1, Natsumi Yamada1, Hiroki Sugishita1,2, Yukiko Gotoh1,2 (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2. International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo)
[1P-109]Identification of histone tails involved in the dynamics of the R-side terminal DNA of the 601 sequence in reconstituted nucleosome core particles in vitro
○Kyohnosuke Shimada1, Masahiro Kawasaki1, Noriyuki Suka1,2 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Prog. in Chem. Life Sci., Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan)
[1P-110]Mechanistic analysis of epigenetic disruption in Facioscapulohumeral muscular dystrophy
○Takumi Kishimoto1,2, Mitsuru Honda2, Satomi Mitsuhashi3, Hidetoshi Sakurai2 (1. Kyoto University, 2. Dept. of Clinical Application, Center for iPS Cell Research and Application, 3. St. Marianna University School of Medicine)
[1P-111(1PS-08-04)]The function of active histone modifications during zygotic genome activation in fish embryos
○Hiroto S Fukushima1,2, Hiroyuki Takeda2,3 (1. RIKEN IMS, 2. The Univ. of Tokyo, 3. Kyoto Sangyo University)
[1P-112]Drug discovery and disease pathogenesis analyses based on transcriptional regulatory landscape
○Zhaonan Zou1, Shinya Oki1 (1. Kumamoto University)
[1P-113]Analysis of the GTP-dependent mechanism using IMD2
Takuma Yokosawa1, Takahito Ayano1, ○Masaya Oki1 (1. University of Fukui)
[1P-114]Centromeric Mating Type loci are regulated by Rpd3L in the budding yeast Ogataea naganishii
○Hiromi MAEKAWA1 (1. Kyushu University)
[1P-115]Molecular organization of the centromeric nucleosome in the yeast minichromosome and genome.
○Nagisa Ochiai1, Miyu Kokai1, Kota Tosaka1, Wataru Kagawa1, Akio Yanagida2, Hiroaki Kato3, Mitsuhiro Shimizu1 (1. Grad. Sch. of Sci. and Eng., Meisei Univ., 2. Sch. Of Pharm., Tokyo Univ. of Pharm and Life Sci., 3. Shimane Univ. Sch. of Med.)
[1P-116]Analysis of the epigenetic mechanisms contributing to the establishment of spermatogonial stem cells
○Tatsuya Fujisawa1, Ryu Maeda1, Yuta Uneme1, Masahide Seki2, Jyo Suzuki2, Mikiko Shiomi1, Soichiro Yamanaka1 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)
[1P-117]An improved method for detecting functional multi-contact regions in the nucleus
○Akira Hirota1, Takumi Wada1, Takuya Yamamoto1,2,3, Taro Tsujimura1 (1. ASHBi, Kyoto Univ. , 2. CiRA, Kyoto Univ. , 3. AIP, Riken)
[1P-118]Variant but not canonical PRC1 deposits H2AK119ub1 on active promoters, priming them for Polycomb-mediated silencing to drive differentiation.
○Mitsuhiro Endoh1, Masaki Okano1, Haruhiko Koseki2, Hitoshi Niwa1 (1. Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, 2. RIKEN IMS)
[1P-119]Towards understanding gene interaction through gene expression data
○Danilo Vasconcellos Vargas1,2,3, Marko Zolo Gozano Untalan1 (1. Kyushu University, 2. The University of Tokyo, 3. MiraiX)
[1P-120]Role of DPPA3 in regulating de novo DNA methylation in mammalian oocytes
○Wan Kin Au Yeung1,2, Hiroaki Ohishi3, Keisuke Toriyama2, Azusa Inoue4, Toshinobu Nakamura5, Toru Nakano6, Hiroyuki Sasaki2 (1. ICU, Col. Liberal Arts, Dept. Natural Sciences., 2. Div. Epigenomics and Development, MIB, Kyushu U., 3. Div. Gene Expression Dynamics, MIB, Kyushu U., 4. Lab. Epigenome Inheritance, IMS, RIKEN, 5. Lab. Epigenetic Regulation, Nagahama Ins. Bio-Sci. Tech., 6. Dept. Pathology, Osaka U.)
[1P-121]Study on the molecular mechanism of a DNA demethylating drug called 5-Azacytidine as an anti-cancer drug in cancer cells.
○Arisa Morita1, Hitoshi Ohtani1 (1. Master of Science in Bioagricultural Sciences, Nagoya University)
[1P-122]Systematic discovery of directional regulatory motifs associated with human insulator sites
○Naoki Osato1 (1. Tokyo Tech.)
[1P-123]Multi-Omics Study on the Regulation of THBS1 in Skin Aging and the Role of Retinoic Acid
○MASATOSHI HAGA1, MARIKO OKADA2 (1. Rohto Pharma. Co., Ltd., 2. Osaka Uni.)
[1P-124]The effect of histone demethylase UTX activity on sex determination
○Mio Kojima1, Mayu Fujita1, Tokuko Iwamori3, Naoki Iwamori1,2 (1. Kyushu Univ., Bioresour. and Environ. Sci., 2. Kyushu Univ., Agriculture, 3. Nakamura Gakuen Univ.)
[1P-125]The role of epigenetic regulator UTX in breast cancer invasion and lung metastasis
○Akiyoshi Komuro1, Ryoichi Sugisawa1, Takeshi Ueda1, Hitoshi Okada1 (1. Dept. of Biochem., Kindai Univ. Fac. of Med.)
[1P-126]Establishment of a methylation capture sequencing protocol for efficient diagnosis of rare monogenic disorders
○Keita Hasegawa1, Keisuke Ishiwata1, Tomoko Kawai1, Hidenobu Soejima2, Nobuhiko Okamoto3, Kenichiro Hata1,4, Kazuhiko Nakabayashi1 (1. National Center for Child Health and Development, 2. Saga University, 3. Osaka Women’s and Children’s Hospital, 4. Gunma University Graduate School of Medicine)
[1P-127]Impact of the Chromatin Remodeler SWI/SNF Complex on Transcriptional Activation by Nuclear Receptor CAR and Its Clinical Significance
○Kiamu Kurosawa1, Masataka Nakano1,2, Itsuki Yokoseki1, Tatsuki Fukami1,2, Yuichiro Higuchi3, Shotaro Uehara3, Nao Yoneda3, Hiroshi Suemizu3, Miki Nakajima1,2 (1. Fac. of Pharm. Sci., Kanazawa Univ., 2. WPI-NanoLSI, Kanazawa Univ., 3. CIEA)
[1P-128]Regulation of osteoclast differentiation and function by epigenetic regulator G9a
○Teruhito Yamashita1, Koichiro Komatsu2, Hisashi Ideno2, Kazuhisa Nakashima2, Yasuhiro Kobayashi1, Nobuyuki Udagawa1, Makoto Tachibana3, Akira Nifuji2 (1. Matsumoto Dental Univ., 2. Tsurumi Univ., 3. Tokushima Univ.)
[1P-129]Mechanism of switching from transcription initiation to elongation by MED26 and TAF7
○Kazuki Furugori1, Hidefumi Suzuki1, Ryota Abe1, Hidehisa Takahashi1 (1. Yokohama City Univ.)
[1P-130]Identification of a critical 3’UTR region for stress-induced suppression of p38 expression in mice hearts
○Risako Ido1, Satoru Iwata2,3,4,5, Takashi Iwamoto1,3, Takehiro Ogata6,7 (1. Graduate School of Life and Health Sciences, Chubu Univ., 2. College of Life and Health Sciences, Chubu Univ., 3. Center for Education in Laboratory Animal Research, Chubu Univ., 4. College of Bioscience and Biotechnology, Chubu Univ., 5. Center for Mathematical Science and Artificial Intelligence, Chubu Univ., 6. Dept of Pathology and Cell Regulation, Graduate School of Medical Sciences, Kyoto Prefectural Univ., 7. Dept of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural Univ.)
[1P-131]Development of novel transcriptional control tools using type I-D CRISPR-Cas system
○Ryuya Watanabe1, Satoshi Kidokoro1, Naoki Wada2, Keishi Osakabe2, Yuriko Osakabe1 (1. Sch. of Life Sci and Tech., Science Tokyo., 2. Grad. Sch. Tech., Ind. and Soc. Sci., Tokushima Univ.)
[1P-132(1PS-03-08)]Structural mechanism of gene transcriptional repression mediated by histone H3 lysine 27 crotonylation
○Tsuyoshi Konuma1 (1. Yokohama City University)
[1P-133]HSF1-CBFA2T2 complex regulates lipid metabolism via a histone demethylase
○MITSUAKI FUJIMOTO1, Ryousuke Takii1, Akanksha Pandey1, Kritika Jaiswal1, Akira Nakai1 (1. Dept. of Biochem. & Mol. Biol., Grad. Sch. of Med., Yamaguchi Univ.)
[1P-134]Large-scale screening of transcriptional repressor capacity by RNA-binding proteins
○Yuki Kojima1,2, Tomohiro Yamazaki3, Aoi Shibuya2, Tetsurou Hirose3, Yuka W. Iwasaki2 (1. University of Tokyo Graduate School/biological science, 2. RIKEN/Yokohama District/Non-Coding Genome Function Research Team, 3. University of Osaka Graduate School/biological function)
[1P-135]Massively parallel assay for decoding the epigenomic functions of cis-reguratory sequences
○Zicong Zhang1, Fumitaka Inoue1 (1. ASHBi, Kyoto University)
[1P-136]Dominant-Negative Variant of Wilms Tumor Suppressor WT1 is implicated in Renal Dysplasia
○Quynh Tran1, Tuyen Thi Thanh Nguyen2, Tatiana Siemko3, Kenji Fukui4, Hiroyasu Tsukaguchi1,5 (1. Kansai Medical University, Second Department of Internal Medicine, 2. Kansai Medical University, Department of Genome Editing, 3. Medical University of Gdansk , 4. Osaka Medical and Pharmaceutical University, 5. Kansai Medical University Hospital Clinical Genetics Center)
[1P-137]CRE-independent regulation of mafA gene transcription by CREB and its co-activator CRTC2
○Yuki Aida1, Kohsuke Kataoka1 (1. Grad. Sch. of Med. Life Sci, Yokohama City Univ.)
[1P-138]Mechanism of PolⅡ pause-release by MED26-mediated recruitment of transcription elongation factors.
○Nanami Yasui1, Hidefumi Suzuki1, Hidehisa Takahashi1 (1. Yokohama City University)
[1P-139]Enhancement of functionality and application of transcriptional activation technologies using Class 1 Type I-E CRISPR system
○Maya Oko1,2, Atsushi Kunii3, Kazuto Yoshimi4, Tomoji Mashimo4, Tetsushi Sakuma2 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. Graduate School of Agriculture, Kyoto University, 3. Graduate School of Science, Hiroshima University, 4. Institute of Medical Science, The University of Tokyo)
[1P-140]Promoter and cis-element analysis:
Transcriptional regulation of mouse type XXVII collagen α1(Col27a1) gene in cartilage
○Mariko Hida1, Mami Yano2, Hiroyuki Yano2,3, Hidekatsu Yoshioka2, Noritaka Matsuo2 (1. Institute for Research Management, Univ. of Oita, 2. Dep. of Matrix Med., Fac. of Med., Univ. of Oita, 3. Dep. of Radiological Science, Univ. of JUNSHIN GAKUEN)
[1P-141]Construction of an inducible gene expression system in Aspergillus oryzae.
○Masaki Yokoyama1, Katsuya Gomi1, Takahiro Shintani1 (1. Grad. Sch. Agric. Sci., Tohoku Univ.)
[1P-142]Regulatory mechanism of gene expression of TA system involved in stress response of Vibrio parahaemolyticus
○Yuta Shiraga1, Takashi Nakashima1, Shunsuke Matsumoto1, Tomoyuki Numata1 (1. Kyushu Univ.)
[1P-143]Functional Interaction of Fibroblast Growth Factor 11 with Chromatin Remodeler CHD1 in Hepatitis B Virus Gene Expression
○Jeong Ah Jang1, Eun Ah Jang 1, Mi So Seong 1, Ye Bin Kim1, Yoon Hee Lee1, Hyun Jin Jeong 1, JaeHun Cheong1 (1. Pusan national university)
[1P-144]MORE-RNAseq: Development of the quantifying method of retrotransposition-capable L1 expression
○Yutaka Nakachi1, Jianbin Du1, Risa Watanabe1, Tomonari Miyatake1, Daisuke Okamoto1, Miki Bundo1, Kazuya Iwamoto1 (1. Dept. of Mol. Brain Sci., Grad. Sch. of Med., Kumamoto Univ.)
[1P-145(1PS-11-07)]Unified identification of transcribed cis-regulatory elements
○Hideya Kawaji1 (1. Tokyo Metropolitan Institute of Medical Science)
[1P-146(1PS-11-06)]FANTOMUS:A large-scale analysis of regulatory elements-associated RNA reveals an important role of regulatory elements in heart failure and skeletal muscle resistance to dystrophy.
○Oleg A. Gusev1, Igor Efimov3, Tatiana Tatarinova3,4, Ruslan Deviatiiarov1,5, Buyan Andrey2, Hayashizaki Yoshihide1,6, Ivan Kulakovskii3,5 (1. Intractable Disease Research Center, Juntendo University, Japan, 2. FANTOM Consortium, Puschino, 3. Northeastern University, USA, 4. The University of La Verne, USA, 5. Life Improvement by Future Technologies Center, Moscow, 6. KK DNAform, Yokohama, Japan)
[1P-147]RNA polymerase II transcription termination maintained by SETD2 methyltransferase activity
○Chihiro Nakayama1,2, Magda Kopczyńska3, Kinga Kamieniarz-Gdula3, Takayuki Nojima2 (1. Cancer Genome Regulation, Faculty of Medical Science, Kyushu University, 2. Cancer Genome Regulation, Medical Institute of Bioregulation, Kyushu University, 3. Center for Advanced Technology, Adam Mickiewicz University)
[1P-148]The p53 target gene p53PAD5 enhances radiation resistance by conferring stress resistance to intestinal epithelial cells
○Tatsuki Yamamoto1,2, Kiyono Aoki1, Hiroshi Takano3, Ayaka Yamamoto4, Shotaro Yamano1, Masanobu Ohshima5, Ryoji Yao3, Toshio Watanabe4, Tomoaki Tanaka2, Rieko Ohki1 (1. Lab. of Fundamental Oncology., Natl. Cancer Ctr. Res. Inst., 2. Dept. Mol. Diag., Chiba Univ. Sch. Med., 3. Dept. Cell Biol., Cancer Inst., JFCR., 4. Grad. Sch. of Humanities & Sci., Nara Women's Univ., 5. Div. Genet., Cancer Res. Inst., Kanazawa Univ.)
[1P-149]Elucidate the molecular mechanisms regulating hepatic Neuregulin 1 transcription.
○Sadatomo Wainai1, Mika Saito1, Chihiro Shimizu1, Shogo Tada1, Nobuhito Goda1 (1. Waseda Univ.)
[1P-150]Transcriptional activity of Ewing's sarcoma oncogene products is regulated by O-GlcNAcylation
○Ryuma Hamaguchi1, Kazuo Kamemura1 (1. Grad. Sch. of Biosci., Nagahama Inst. of Bio-Sci. and Technol.)
[1P-151]Nuclear Aurora-A acetylation promotes activation of NF-Y transcriptional program and mitotic bookmarking
○Hiroshi Katayama1, Arnab Bose2, Warapen Treekitkarnmongkol1, Hiroki Shima3, Kazuhiko Igarashi3, Roberto Mantovani4, Subrata Sen1 (1. University of Texas MD Anderson Cancer Center, 2. Jawaharlal Nehru Centre for Advanced Scientific Research, 3. Tohoku University Graduate School of Medicine, 4. Università degli Studi di Milano)
[1P-152]Evaluating the Influence of Reference Networks on Gene Regulatory Network feature Metrics
○Gina Miku Oba1, Ryuichiro Nakato1 (1. IQB, Univ. of Tokyo)
[1P-153]Autoactivation mechanism of transcription factor via read-through transcription that ensures virulence in Vibrio parahaemolyticus
○Eiji Ishii1,2, Dhira Saraswati Anggramukti1,3, Andre Pratama1, Mohamad Al Kadi4, Tetsuya Iida1,2, Toshio Kodama5, Shigeaki Matsuda1,2 (1. RIMD, Osaka Univ., 2. CiDER, Osaka Univ., 3. RITE, 4. iFREC, Osaka Univ., 5. NEKKEN, Nagasaki Univ.)
[1P-154]Analysis for mRNA involved in regulation of chromosome dynamics
○Yukino Minami1, Tani Tokio2, Takashi Ideue2 (1. Graduate School of Science Kumamoto Univ. , 2. Faculty of Advanced Science and Technology Kumamoto Univ.)
[1P-155]Establishing Molecular Basis for the Three Major Genera of the Myxomycetes Family Physaraceae
○Mana Masui1,2, Phillip Yamamoto1,2, Nobuaki Kono1,2,3 (1. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 2. Inst. Adv. Biosci., Keio Univ., 3. Environment & Info. Studies, Keio Univ.)
[1P-156]Understanding the mechanism underlying the induction of pancreatic cancer malignancy by the acquired gain of function of passenger RNAs.
○Mayuka Ohkawa1,2, Motomi Yamazaki1, Jun Koseki1,3, Shunsuke Shunsuke4, Yasuhiro Ozeki2, Teppei Shimamura3,5, Masamitsu Konno1,2 (1. Cell&Mol. Bioltech. Res. Inst. AIST, 2. Grad. Sch. of NanoBiosci. YCU, 3. Grad. Sch. of Med. Nagoya Univ., 4. Res. Inst. for Biomed. Sci. Tokyo Univ. of Sci., 5. Med. Res. Inst. Tokyo Med. Dent. Univ.)
[1P-157(1PS-03-03)]Anemia caused by disruption of the noncanonical complex of 7SLRNA
○Chisa Shiraishi1, Kazuya Ichihara1, Taichi Shiraishi1, Akinobu Matsumoto1 (1. Nagoya university)
[1P-158]Interaction between fluoroquinolone derivatives and RNA: analysis of binding specificity of KG022
○Rika Ichijo1, Gota Kawai1 (1. Chiba Institute of Technology)
[1P-159]PCIS1, encoded by a pentatricopeptide protein co-expressed gene, is required for splicing of three mitochondrial nad transcripts in seed plants
Brody Frink1, Burger Matthias4, Yarkoni Maya3, Shevtsov-Tal Sofi3, Zer Hagit3, Shohei Yamaoka2, Osterzetzer-Biran Oren3, ○Mizuki Takenaka1 (1. Grad. Sch. Sci., Kyoto Univ., 2. Grad. Sch. Life Sci., Kyoto Univ., 3. The Hebrew Univ. of Jerusalem, Israel, 4. Ulm Univ. Germany)
[1P-160]Understanding heterogeneity in maternal piRNAs inheritance by single-egg small-RNA sequence
○Makoto Endo1,2, Keisuke Shoji3, Takashi Kiuchi4, Susumu Katsuma4, Yukihide Tomari*1,2, Fumiko Kawasaki*1 (1. IQB, Univ. of Tokyo, 2. Dept. of C. Bio. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 3. Dept. of BFSS., Grad. Sch. of BASE., Tokyo Univ. of Agri. and Tech., 4. Dept. of Agri. and Env. Bio., Grad. Sch. of Agri. and Life Sci., Univ. of Tokyo)
[1P-161]A functional connection between the Microprocessor and a variant NEXT complex
○Katsutoshi Imamura1,2, Torben Heick Jensen2 (1. Chiba University, 2. Aarhus University)
[1P-162]Thermodynamics model of nuclear stress body based on phase separation
○Tetsuya Yamamoto1, Kensuke Ninomiya2, Tomohiro Yamazaki2, Tetsuro Hirose2 (1. Hokkaido Univ., 2. Osaka Univ.)
[1P-163]The third biosynthesis pathway of 4-thiouridine in tRNA
○Sota Yamasaki1, Yuzuru Sugio1, Junya Ueda1, Ryo Isogai1, Natsumi Matsumoto1, Takuya Kawamura1, Chie Tomikawa1, Minoru Hayashi1, Ryota Yamagami1, Akira Hirata2, Satoshi Ohno3, Takashi Yokogawa3,4,5, Hiroyuki Hori1 (1. Graduate School of Science and Engineering, Ehime University, 2. Graduate School of Technology, Industrial and Social Science, Tokushima University, 3. Faculty of Engineering, Gifu University, 4. Tokai National University Organization, Research and Education Center for the Development and Fostering of One Medicine Seeds, 5. The United Graduate School of Drug Discovery and Medical Informatics, Gifu University)
[1P-165]Mechanistic analysis of liquid-liquid phase separation driven perinucleolar compartment (PNC) formation in cancer cells
○Gideon Kipkemoi1, Fan Kaidi1, Cao Leyan1, Wang Wenhao1, Haruko Takahashi1, Yutaka Kikuchi1 (1. Grad. Sch. Integrated Sci. for Life, Hiroshima University)
[1P-166]Pre-rRNA processing mechanism involving NVL2-dependent regulation of the WDR74 module interactions
○Yuya Hirooka1, Sotaro Miyao1, Keiichi Izumikawa1, Masami Nagahama1 (1. Meiji Pharmaceutical University)
[1P-167]Expression of transposable elements suppresses by piRNAs during mouse oogenesis
○Taichi Harimoto1,2, Shohei Kojima1, Rie Koide1, Nicholas Parrish1 (1. RIKEN IMS, 2. Yokohama City University)
[1P-168]Nucleo-cytoplasmic shuttling of RNA helicase Vasa mediates the accumulation of transposon transcripts into Vasa bodies
○Mizuki Fukuda1, Yamazaki Hiroya1, Mikiko C Siomi1 (1. School of Science, The University of Tokyo)
[1P-169]Analysis of autoregulation mechanism of RNA exosome adaptor protein SPF30
○Tatsuya Shida1, Keiichi Izumikawa1, Onodera Yuka1, Sotaro Miyao1, Minoru Sugihara2, Tamotsu Noguchi2, Masami Nagahama1 (1. Laboratory of Molecular and Cellular Biochemistry, Meiji Pharmaceutical University, 2. Meiji Pharmaceutical University)
[1P-170]Optimization of tRNA biotinylation by MTSEA-biotin
○Futa Konishi1, Hiroyuki Hori1, Ryota Yamagami1 (1. Graduate School of Science and Engineering Ehime Univ.)
[1P-171]Circular RNA in Osteoarthritis
○Masayuki Takeda1, Ryota Kurimoto1, Takahide Matsushima1, Tomoki Chiba1, Hiroshi Asahara1 (1. Institute of Science Tokyo)
[1P-172]Regulation of YIPFα1A expression by the 3'UTR
○Yurika Nakanishi1, Nobuhiro Nakamura1 (1. Kyoto Sangyo University)
[1P-173]Cap specific m6A methyltransferase PCIF1/CAPAM modulates type I IFN responses
○Ryoya Kano1, Chihiro Oyama1, Chihiro Ikeda1, Ai Sugita1, Hiroyasu Ishiguro1, Aki Tanaka1, Akiko Inujima2, Keiichi Koizumi3, Shinichiro Akichika4, Tsutomu Suzuki4, Yoshiaki Tabuchi5, Yoshiaki Ohkuma6, Yutaka Hirose1 (1. Grad. Sch. of Med. & Pharm. Sci., Univ. of Toyama, 2. Div. of Med. Oncology, Cancer Res. Inst., Kanazawa Med. Univ., 3. Div. of Presymptomatic Disease, Inst. of Natural Med., Univ. of Toyama, 4. Grad. Sch. of Eng., Univ. of Tokyo, 5. Life Science Res. Center, Univ. of Toyama, 6. Grad. Sch. of Biomed. Sci., Nagasaki Univ.)
[1P-174]Analyses of subclass-specific structure and function of nuclear stress bodies
○Yumena Masuda1, Kensuke Ninomiya2, Junichi Iwakiri3, Kiyoshi Asai3, Tetsuro Hirose1,2,4 (1. Dpt.of Biol. Sci.,Grad. Sch. of Sci., Osaka Univ., 2. Grad. Sch. of FBS, Osaka Univ., 3. GSFS, UTokyo, 4. OTRI, Osaka Univ.)
[1P-175]A regulatory role of circRNA-miR-mRNA network in trophoblast lineage
○Junko Tomikawa1, Chiharu Tayama1, Keisuke Ishiwata1, Kohji Okamura1, Kennichiro Hata1,2, Kosuke Taniguchi1,2, Tomoko Kawai1 (1. National Research Institute for Child Health and Development, 2. Gunma University Graduate School of Medicine)
[1P-176]A fast in situ hybridization chain reaction method in Drosophila embryos and ovaries
○Kyohei Mikami1,2, Yasuhiro Kozono1,2, Masaki Masukawa1,2, Satoru Kobayashi1,2 (1. Degree Prog. in Life and Earth Sci., Univ. of Tsukuba, 2. Life Sci. Ctr. Surv. Dyn. TARA., Univ. of Tsukuba)
[1P-177]Identification of oxidative stress dependent mitochondrial tRNA modification
○Raja Norazireen Raja Ahmad1, Akiko Ogawa1, Long-Teng Zhang1, Kazuyasu Kanazawa1, Tomohiro Sawa2, Fan-Yan Wei1 (1. Department of Modomics Biology and Medicine, Institute of Development, Aging and Cancer, Tohoku University, 2. Department of Microbiology, Faculty of Life Sciences, Kumamoto University)
[1P-178]Regulation of gene expression networks by ADAR1p150 through microRNAs during interferon response
○Toyotaka Yoshida1, Yoshimasa Asano1,2, Shota Azuma1, Kumiko Ui-Tei1,3 (1. The University of Tokyo, 2. Nihon University, 3. Institute of Science Tokyo)
[1P-179]Development of long-read scRNA-seq protocol with target capture
○Gento Fujii1, Masahide Seki1, Junko Zenkoh1, Ayako Suzuki1, Yutaka Suzuki1 (1. Department of Computational Biology and Medical Sciences, Graduate School of Frontier, Tokyo University)
[1P-180]Search for interacting partners of intron-containing tRNALeuCAA in Saccharomyces cerevisiae
○Ryu Kutose1, Tohru Yoshihisa2, Sachiko Hayashi2 (1. Faculty of Science, University of Hyogo, 2. Graduate School of Science, University of Hyogo)
[1P-181]MOV10L1 S818I mutant mouse, a model of male infertility, shows unique phenotypes distinct from MOV10L1-deficient mouse
○Yanling Wei1, Shigeki Hirakata1, Ryuki Shimada2, Yuica Koga1, Soichiro Yamanaka1, Naoki Takeda2, Kimi Araki2, Kei-ichiro Ishiguro2, Mikiko C Siomi1 (1. The University of Tokyo, 2. Kumamoto University)
[1P-182]Recognition mechanism of the 5'-end and the CCA sequence of tRNATyr by Nanoarchaeum equitans TyrRS
○Hyuga Mizumata1, Hiromi Mutsuro1, Yusuke Saga1, Koji Tamura1,2 (1. Dept. of Biol. Sci. & Technol., Tokyo Univ. of Sci., 2. Res. Inst. for Sci. & Technol., Tokyo Univ. of Sci.)
[1P-183]Creation and minimization of self-replicating ligase ribozymes
○Rinko Yamaguchi1, Hiromi Mutsuro-Aoki1, Yusuke Saga1, Koji Tamura1,2 (1. Dept. of Biol. Sci. & Technol., Tokyo Univ. of Sci., 2. Res. Inst. for Sci. & Technol., Tokyo Univ. of Sci.)
[1P-184]In vitro reconstitution of the signal recognition particle
○Saaya Toyota1, Fuka Kanemitsu1, Mako Yumita1, Mayumi Sunagawa1, Kodai Machida1, Hiroaki Imataka1 (1. Dept. of Appl. Chem., Grad. Sch. of Eng., Univ. of Hyogo)
[1P-185]Functional analysis of proteoliposomes containing SR receptors and Sec translocons
○Fuka Kanemitsu1, Saaya Toyota1, Mako Yumita1, Kodai Machida1, Hiroaki Imataka1 (1. Dept. of Appl. Chem., Grad. Sch. of Eng., Univ. of Hyogo)
[1P-186]Release mechanism of a novel translation arrest sequence and regulation of downstream gene expression in Escherichia coli
○Akinao Kobo1, Yushin Ando2, Yuzuru Itoh2, Hideki Taguchi1,3, Osamu Nureki2, Yuhei Chadani4 (1. Sch. Life Sci. Tech., Science Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 3. Cell Biol. Ctr., IIR, Science Tokyo, 4. Dept. of Biol. Fac. of Sci., Okayama Univ.)
[1P-187]Tissue-specific translational regulation of the serine racemase Srr by uORF
○Yuta Takahashi1, Chisa Shiraishi1, Kazuya Ichihara1, Hiroki Shikanai2, Takeshi Izumi2, Akinobu Matsumoto1 (1. Division of Biological Science, Graduate School of Science, Nagoya University, 2. Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido)
[1P-188]Polyamines enhance RAN translation by stabilizing the tertiary structure of repeat RNA
○Akihiro Oguro1, Takeshi Uemura2, Kodai Machida3, Kanta Kitajiri3, Ayasa Tajima1, Gota Kawai4, Hiroaki Imataka3 (1. The Jikei University School of Medicine, 2. Josai University, 3. University of Hyogo, 4. Chiba Institute of Technology)
[1P-189]The hibernation promoting factor (HPF) of Betaproteobacteria Comamonas testosteroni cannot induce 100S ribosome formation but stabilizes 70S ribosomal particles.
○Masami Ueta1, Akira Wada1, Chieko Wada1 (1. Yoshida biological laboratory Co., ltd)
[1P-190]Function analysis of arrest peptide from Brevibacillus genus
○Yudai Ogasawara1, Keigo Fujiwara2, Hiraku Takada3, Shinobu Chiba1 (1. Kyoto Sangyo University, 2. The National Institute of Genetics, 3. TOYAMA Prefectural University)
[1P-191]Structural and Functional Analysis of Peptidyl-tRNA Hydrolase Pth2
○Aoi Kawashima1, Akihisa Ichimura1, Masateru Chihara1, Shungo Mizusawa1, Shuh-ichi Nishikawa1, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ.)
[1P-192(1AS-05-01)]Development of Human PURE coupled with ER-like liposomes
○Hiroaki Imataka1, Mayumi Sunagawa1, Kodai Machida1, Fuka Kanemitsu1, Saaya Toyota1, Mizuki Okabayashi1, Mako Yumita1, Yuto Ushijima1, Takumi Miyawaki1 (1. University of Hyogo)
[1P-193]Characterization of proteins starting with a poly-alanine stretch
○Atsushi Hatano1, RIsa Ikarashi1, Toukichiro Abe1, Tomoyo Takami1, Masaki Matsumoto1 (1. Graduate School of Medical and Dental Sciences, Niigata University)
[1P-194]Analysis of the molecular and physiological roles of Cnot4 in zebrafish
○Kouya Kageyama1, Chihiro Hayashida1, Yuichiro Mishima1 (1. Division of Life Sciences, Graduate School of Life Sciences, Kyoto Sangyo University)
[1P-195]Functional analysis of Bacillus subtilis arrest peptide YwcI
○Momoka Sano1, Keigo Fujiwara2, Shinobu Chiba1 (1. Kyoto Sangyo University, 2. National Institute of Genetics)
[1P-196]Functional analysis of polysome formation of murine leukemia virus mRNA
○Tsukasa Koreeda1, Kenshi Aburatani1, Sayaka Takase-Yoden1,2 (1. Department of Biosciences, Graduate School of Science and Engineering, Soka University, 2. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[1P-197]Analysis of cis-elements contributing polysome formation of full-length mRNA of murine leukemia virus
○Ryoichi Takano1, Tsukasa Koreeda1, Keisuke Yonebayashi1, Sachie Torii1, Sayaka Takase-Yoden1,2 (1. Department of Biosciences, Graduate School of Science and Engineering, Soka University, 2. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[1P-198]Dynamics and physiological functions of tRNA queuosine modification in zebrafish
○Ryota Matsue1, Toru Irie1, Kota Ishibashi1, Kimi Wakabayashi1, Yuichiro Mishima1 (1. Kyoto sangyo university)
[1P-199]Analysis of the effects of RQC deficiency in zebrafish znf598 mutant embryos.
○Midori Iguchi1, Kota Ishibashi1, Kimi Wakabayashi1, Yuichiro Mishima1 (1. Kyoto Sangyo University)
[1P-200]Antagonistic mechanism between RNA-binding protein and microRNA mediated by Akt signaling
○So Toshima1, Takumi Tomohiro1, Akira Fukao1, Yoshinori Funakami1, Toshinobu Fujiwara1 (1. Kindai university)
[1P-201]Functional analysis of the movable loop region of the bacterial outer membrane quality control BepA protease
○Ryoji Miyazaki1, Takeru Nishi1, Mai Kimoto1, Yasushi Daimon2, Tomoya Tsukazaki1, Yoshinori Akiyama2 (1. NAIST, 2. Kyoto Univ.)
[1P-202]Interaction analysis of periplasmic chaperone SurA with the BAM complex
○Nami Matsuoka1, Wataru Yoshimoto1, Hidetaka Kohga1, Ryoji Miyazaki1, Tomoya Tsukazaki1 (1. NAIST)
[1P-203]Mechanism for promoting the maturation of a bacterial outer membrane protein by a small outer membrane lipoprotein
○Mai Kimoto1, Ryoji Miyazaki1, Hidetaka Kohga1, Tomoya Tsukazaki1 (1. NAIST)
[1P-204]Deciphering the Multi-state Conformational Equilibrium of MDM2 in the Regulation of p53 Binding: Perspectives from Molecular Dynamics Simulation and NMR Analysis
○Qingci Zhao1, Kazuki Watanabe1, Ryosuke Iwatsuki1, Ryota Fukui1, Weitong Ren2, Yuji Sugita2, Noritaka Nishida1 (1. Chiba University, 2. RIKEN)
[1P-205]Conformational dynamics of MDM2 in the regulation of p53 binding under molecular crowding environment
○Ryota Fukui1, Ryosuke Iwatsuki1, Kazuki Watanabe1, Qingci Zhao1, Noritaka Nishida1 (1. Chiba Univ.)
[1P-206]Elucidating the aggregation mechanism of α-synuclein under intracellular molecular crowding environment by NMR analysis
○Saki Nakagawa1, Rina Miyaoi1, Yuto Tsumura1, Qingci Zhao1, Noritaka Nishida1 (1. Chiba Univ.)
[1P-207]Characterisation of mutations that restore lost histamine H3 receptor signalling activity in a budding yeast expression system.
○Ami Nakajima1, Chiaki Arai1, Hiroto Kaneko1, Mitsunori Shiroishi1 (1. Dept. of.Biol. Sci. and Technol., Tokyo Univ. of Sci.)
[1P-208]Elucidation of molecular recognition mechanism of rheumatoid factor RF-TS2 and HUL-mRF
○Yusuke Nakamura1, Maruto Yamoto1, Mitsunori Shiroishi1, Kousuke Oyama1 (1. Dept. of Biol. Sci. and Technol., Tokyo Univ. of Sci.)
[1P-209]Binding characteristics of the doxepin E/Z isomers to the histamine H1 receptor revealed by receptor-bound ligand analysis and molecular dynamics study
○Hiroto Kaneko1, Ryunosuke Korenaga1, Tadashi Ando2, Mitsunori Shiroishi1 (1. Dept. of Biol. Sci. and Technol. Tokyo Univ.of Sci., 2. Dept. of Appl. Electronics., Tokyo Univ. of Sci.)
[1P-210]Fabrication of fluorescent immunosensors by site-specific cross-linking using transglutaminase
○Yoshiyuki Ueno1, Takanobu Yasuda2, Bo Zhu2, Riko Nishioka3, Noriho Kamiya3,4, Tetsuya Kitaguchi2 (1. Graduate School of Life Science and Technology, Tokyo Institute of Technology, 2. Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 3. Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 4. Division of Biotechnology, Center for Future Chemistry, Kyushu University)
[1P-211]PET degradation activity of novel PET-degrading enzymes from a compost metagenome
○Koki Hata1, Natsuki Abe1, Ryo Iizuka2, Masafumi Yohda1, Toshiyuki Moriya4, Tairo Oshima4, Keiichi Nogchi3 (1. Dept. of Biotechnology and Life Science, Tokyo Univ.of Agriculture and Technology, 2. Graduate School of Science, The Univ. of Tokyo, 3. Research Center for Science and Technology,Tokyo Univ.of Agriculture and Technology, 4. Institute of Enviromental microbiology, kyowa kako Co.,LTd)
[1P-212]Development of bivalent human VH single-domain antibodies inhibiting liver fibrosis
○Taihei Nagafuchi1, Kei Fujiwara1, Hikari Okada2, Masao Honda2, Nobuhide Doi1 (1. Keio Univ., 2. Kanazawa Univ.)
[1P-213]TIMM17A, a subunit of mitochondrial inner membrane translocator, is degraded by YME1L1 when being unoccupied by precursors.
○Hiroki Kinefuchi1, Meng-Chieh Hsu2,3, Richard J. Youle2, Noriyuki Matsuda1, Koji Yamano1 (1. Medical Research Institute, Tokyo Medical and Dental Univ., 2. National Institute of Neurological Disorders and Stroke, National Institutes of Health, 3. Department of Animal Science and Technology, National Taiwan Univ.)
[1P-214]Structural analysis of the Homininae-specific de novo evolved protein NCYM
○Kazuma Nakatani1,2, Seigi Yamamoto2, Fumiaki Kono3, Tatsuhito Matsuo4, Koichi Matsuo5, Assia Mouhand6, Philippe Barthe6, Judith Peters7, Christian Roumestand6, Miwako Hirose8, Katsunori Horii8, Taro Tamada3, Yoshitaka Hippo1,2,9, Yusuke Suenaga2 (1. Grad. Sch. of Med. & Pharm. Sci., Chiba Univ., 2. Lab. of Evolutionary Oncology, CCCRI, 3. Inst. for Quantum Life Sci., QST, 4. Fac. Health Sci., Hiroshima Int. Univ., 5. Res. Ins. Syn. Rad. Sci., Hiroshima Univ., 6. Centre de Biologie Structurale, Montpellier Univ., 7. Institut Laue Langevin, 8. NEC Solution Innovators, Ltd., 9. Lab. of Precision Tumor Model Systems, CCCRI)
[1P-215]Anionic detergents facilitate wasp mastoparan-induced Gαi activation
○Takaya Ogura1, Tatsuya Ikuta1, Hiroki Arai1, Masataka Yanagawa1, Asuka Inoue1,2 (1. Grad. Sch. of Pharm. Sci., Tohoku Univ., 2. Grad. Sch. of Pharm. Sci., Kyoto Univ.)
[1P-216]The C-edge loop of β-arrestin regulates its recruitment to the membrane.
○Chihiro Watanabe1, Ritsuki Kuramoto1, Asuka Inoue1,2 (1. Grad Sch of Pharm Sci, Tohoku Univ, 2. Grad Sch of Pharm Sci, Kyoto Univ)
[1P-217]PIWI-proxity proteome screening for deciphering piRNA-mediated transposon silencing
○Wakana Fujiyasu Isshiki1, Taichiro Iki1, Chinyere MaryCynthia Ikele1, Masaaki Oyama2, Hiroko Kozuka Hata2, Toshie Kai1 (1. Osaka Univ., 2. Tokyo Univ.)
[1P-218]The study of molecular details of the interaction between α Synuclein and G4RNA
○YIRAN CHEN CHEN1, Hidehito Tochio1, Yasushi Yabuki2, Norifumi Shioda2 (1. Kyoto University, 2. Kumamoto University)
[1P-219]Substrate preferences of the anti-HIV factor APOBEC3C and the effect of HIV-1 Vif-human E3 ubiquitin ligase complex on deaminase activity
○Kentaro Tozawa1,2, Keisuke Kamba1, Ryo Iwaoka1,2, Takashi Nagata1,2, Masato Katahira1,2 (1. Inst. Adv. Energy, Kyoto Univ., 2. Grad. Sch. Energy Sci., Kyoto Univ.)
[1P-220]Exploring the relationship between molecular evolution and substrate specificity of SMR multidrug efflux transporters by molecular phylogenetic analysis
○Yuta Ogawa Ogawa1, Nachi Yamamoto2, Kenichi Nishiyama2, Liam M Longo3, Tomoaki Matsuura3 (1. LST, Tokyo Tech, 2. Dept. of Biol. Chem., Fac. of Agriculture, Iwate Univ., 3. ELSI, Tokyo Tech)
[1P-221]Structure and function of PDIR, a member of the PDI family
○Kota Azuma1,3, Motonori Matsusaki2, Satoshi Watanabe3, Kenji Inaba3 (1. Dept. of Chem., Grad. Sch. of Sci., Tohoku Univ., 2. IAMS, Tokushima Univ., 3. MIB, Kyushu Univ.)
[1P-222]Functional Analysys of Lipocalin Prostaglandin D Synthase Analogue
○Chinatsu Noma1, Koichi Uegaki3, Kazuki Kawahara2, Kodai Nakamoto1, Yuji Hidaka1, Shigeru Shimamoto1 (1. Graduate School of Science and Engineering, Kindai University, 2. Graduate School of Pharmaceutical Sciences, Osaka University , 3. Graduate School of Agriculture, Kindai University)
[1P-223]Conformational predictions of the multi states in the transmembrane dimer of Receptor Tyrosine Kinase (RTK).
○Naoto Tonogaito1, Ryo Fujimoto1, Shota Shimogouchi1, Naoyuki Miyashita1,2 (1. Grad. Sch. BOST,Kindai Univ., 2. BOST Kindai Univ.)
[1P-224(1AS-05-04)]Large-scale identification of noncanonical proteins based on proteomics
○Riko Egawa1, Hiroshi Nishida1, Yuta Kochi3, Kosuke Ogata1, Yasushi Ishihama1,2 (1. Graduate School of Pharmaceutical Sciences, Kyoto University, 2. National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 3. Medical Research Institute, Tokyo Medical and Dental University)
[1P-225]Dissociation processes of the nucleic binding protein TALE and PPRP from the nucleic acids.
○Sumile Tanaka1, Yuma Shiota1, Ryusei Haruna1, Naoyuki Miyashita1 (1. KINDAI Univ.)
[1P-226]Development of a temperature-dependent protein dimerization system using a mutant leucine zipper
○Kanako Kojima1, Shu Kondo1 (1. Department of Biological Science and Technology, Tokyo University of Science)
[1P-227]Structural biology analysis of the regulation of HOIP activity by HOIL-1L
○Marina koga1, Kayo Imamura1, Takayuki Kato3, Mika Hirose3, Keiichi Namba2, tomoko Miyata2, Kazuki Kasai2 (1. Kyoto Univ. Graduate School of Science, 2. Osaka Univ. Graduate School of Frontier Biosciences, 3. Osaka Univ. Institute for Protein Research)
[1P-228]Quality evaluation of human P-glycoprotein nanodisc by a novel method using SEC-SAXS
○Yuri Hariki1, Mako Kikuchi2, Norie Hamaguchi1, Sisi Chin1, Souichi Yamashita1, Satoshi Ogasawara1, Nobutaka Shimizu2,3, Takeshi Murata1 (1. Chiba University, 2. PF, IMSS, KEK, 3. RIKEN SPring-8 Center)
[1P-229]Structural study of the complex of protein arginine methyltransferase 1 and substrate EWS
○Nobuyuki Endo1, Sachiko F-Toma2,3, Hinako Koshimura2, Akihiro Kawamoto1, Mika Hirose1, Akiko Ikegami2, Miwa Kuzuhara2, Hiroaki Daitoku3,4, Koichiro Kako5, Takayuki Kato1, Akiyoshi Fukamizu3,4, Hironari Kamikubo2, Genji Kurisu1 (1. Osaka Univ., IPR, 2. NAIST, 3. AMED-CREST, 4. Tsukuba Univ., TARA, 5. Tsukuba Univ.)
[1P-230]Dynamic action of mycobacterial intrinsically disordered histone-like protein in DNA compaction that induces mycobacterial dormancy
○Akihito Nishiyama1, Masahiro Shimizu2,3, Tomoyuki Narita3, Noriyuki Kodera3, Yuriko Ozeki1, Akira Yokoyama1, Kouta Mayanagi4, Takehiro Yamaguchi5, Yoshitaka Tateishi1, Sohkichi Matsumoto1 (1. Bacteriology, Niigata Univ. Sch. Med., 2. Inst. Integr. Radiat. Nuclear Sci., Kyoto Univ., 3. NanoLSI, Kanazawa Univ., 4. Pharm Sci., Kyushu Univ, 5. Pharmacol., Osaka Metro. Univ. Med. Sch.)
[1P-231]Substrate specificity of RAB7A-chaperone
○Kei Okatsu1, Koji Yamano2, Noriyuki Matsuda2, Shuya Fukai1 (1. Kyoto Univ., 2. Tokyo Med. & Dent. Univ.)
[1P-232]The Quest to Discover New Substrates Related K48/K63 Branched Ubiquitin Chains
○Shota Tomomatsu1, Takuya Tomita2, Yasushi Saeki2, Fumiaki Ohtake1 (1. Hoshi University, 2. The Institute of Medical Science, The University of 8 Tokyo)
[1P-233]Evaluation of the applicability of Quenchbody in clinical laboratory testing
○Kenta Kiguchiya1, Yusuke Murakami1, Masaki Sato1, Yoshiyuki Ohiro1, Takanobu Yasuda2,3, Tetsuya Kitaguchi2,3 (1. Eiken Chemical Co., Ltd., 2. Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 3. HikariQ Health, Inc.)
[1P-234]Activity regulation of the scramblase XKR8 by its C-terminal intracellular region
○Takaharu Sakuragi1, Ryuta Kanai2, Mayumi Otani1, Masahide Kikkawa3, Chikashi Toyoshima2, Shigekazu Nagata1 (1. Laboratory of Biochemistry and Immunology, Immunology Frontier Research Center, Osaka University, 2. Laboratory of Membrane Proteins, Institute for Quantitative Biosciences, The University of Tokyo, 3. Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo)
[1P-235]Single particle cryo-EM analysis of bacterial RND-type multidrug efflux pump
○Satomi Inaba-Inoue1,2, Toshio Moriya2, Toyoyuki Ose1, Mikio Tanabe2 (1. Fac of Adv Life Sci, Hokkaido Univ, 2. KEK, IMSS, SBRC)
[1P-236]Ancestral sequence reconstruction of lysyl-tRNA synthetases implies the thermophilicity of the last CPR common ancestor
○Madoka Kimura1, Sota Yagi1,2, Satoshi Akanuma1 (1. Grad. Sch. Hum. Sci., Waseda Univ., 2. RIKEN BDR)
[1P-237]Analysis of the σ32 metabolic mechanism by FtsH.
○Shion Sato1, Toshifumi Tomoyasu1,2, Atsushi Tabata1,2, Hideaki Nagamune1,2, Bernd Bukau3 (1. Div. Bioresour. Sci.,Grad. Sch. Sci. & Tech. for Innov.,Tokushima Univ, 2. Div. Biosci. & Bioindust., Grad. Sch. Tech., Indust. & Soc. Sci., Tokushima Univ., 3. Center for Molecular Biology of Heidelberg Univ.)
[1P-238]Functional and structural analyses of the intracellular region of myelin protein zero, the causative gene product of Charcot-Marie-Tooth disease.
○Mina Nakayama1, Kotaro Okamura2, Kazuhiro Mio2,3, Sakakura Masayoshi1,2 (1. School of Sci, Yokohama City Univ., 2. Grad School of Med Life Sci, Yokohama City Univ., 3. AIST-UTokyo operando OIL)
[1P-239]Analysis of the interaction between a dormancy regulator and DNA Gyrase from Mycobacterium tuberculosis
○Yuri Nakagawa1, Yuuka Kawanobe1, Koki Watanabe1, Akihito Nishiyama2, Yuriko Ozeki2, Sohkichi Matsumoto2, Kosuke Ito1 (1. Grad. Sch. of Sci. & Tech., Niigata Univ, 2. Grad. Sch. of Medical and Dental Sci., Niigata Univ)
[1P-240(1AS-06-05)]Functional analysis of RABIF/MSS4 in RAB protein quality control
○Ryu Endo1, Mitsunori Fukuda2, Noriyuki Matsuda1, Koji Yamano1 (1. Tokyo Medical and dental univ., 2. Tohoku Univ.)
[1P-241]Functional analysis of the DnaK chaperone system in Brevibacillus sp.
○Kyohei Fukumura1, Ryota Okamoto1, Toshifumi Tomoyasu1,2, Atsushi Tabata1,2, Hideaki Nagamune1,2 (1. Div. Bioresour. Sci., Grad. Sch. Sci. & Tech. for Innov., Tokushima Univ., 2. Div. Biosci. & Bioindust., Grad. Sch. Tech., Indust. & Soc. Sci., Tokushima Univ.)
[1P-242]Structural and Functional Analysis of the Venezuelan Equine Encephalitis Virus nsP2 Helicase
○Yuka Yuka Mishima1, Ryo Uehara1, Takuya Yoshizawa1, Etsuko Katoh2, Hiroyoshi Matsumura1 (1. Ritsumeikan Univ., 2. Toyo Univ.)
[1P-243]Analysis of proton-pumping rhodopsin RxR variants for conversion of pump function
○Yusuke Abe1, Chika Hoyano2, Reika Hironishi2, Masafumi Hirohata2, Rika Suzuki2, Keiichi Kojima3, Yuki Sudo3, Hideo Takahashi2 (1. Dept. of Med. Life Sci., Sch. of Sci. Life Sci., YCU, 2. Grad. Sch. of Med. Life Sci., YCU, 3. Grad. Sch. of Med., Dent. and Pharma. Sci., Univ. of Okayama)
[1P-244]Preparation of the expression system for a Mycobacterium tuberculosis dormancy regulator and enolase, and analysis of their interaction
○Nanami Yagi1, Yuuka Kawanobe1, Kodai Kamba1, Akihito Nishiyama2, Yuriko Ozeki2, Sohkichi Matsumoto2, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ, 2. Grad. Sci. of Medical and Dental Sci., Niigata Univ)
[1P-245]Development of a novel off-target evaluation method to ensure the safety of targeted protein degradation drug (PROTAC)
○Nobumichi Ohoka1, Takenori Yamamoto1, Tokuyuki Yoshida1, Takao Inoue1 (1. NIHS)
[1P-246]Structural Insights into the Arabidopsis tRNA Splicing Endonuclease (AtSen) Complex
○Mohammad Moniruzzaman1, Kazuhito Akama1 (1. Graduate School of Natural Science and Technology, Shimane University)
[1P-247]Molecular mechanism of cPGA degradation activity of Parkinson's disease causative factor DJ-1
○Aiko Watanabe1, Mirei Saito1, Yoshitaka Moriwaki2, Ryuichiro Ishitani2, Noriyuki Matsuda1 (1. Dept. Biomolecular Pathogenesis, MRI, Tokyo Med. and Dent. Univ., 2. Dept. Computational Drug Discovery and Design, MRI, Tokyo Med. and Dent. Univ.)
[1P-248]Elucidation of the mechanism of inducing structural asymmetry in homodimeric enzymes using molecular dynamics calculations
○Yoshino Okamoto1, Yakunori Yasuda1, Rikuri Morita2, Yasuteru Shigeta2, Ryuhei Harada2 (1. Graduate School of Biology, University of Tsukuba, 2. Center for Computational Sciences, University of Tsukuba)
[1P-249]Comparative functional analysis of haplotypes for the novel cancer stem cell marker OR7C1
○Masaki Okajima1, Kaoru Hashimoto2, Suzuna Kozu2, Yoshihiko Hirohashi3, Toshihiko Torigoe3, Masafumi Yohda1,2, Yousuke Fukutani1,2 (1. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol., 2. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol.,, 3. Dept of Pathol. Sapporo Med. Univ.)
[1P-250]Identification of γ-secretase complex in the intestinal protozoan parasite Entamoeba histolytica
○Takashi Makiuchi1, Yumiko Saito-Nakano2, Tomoyoshi Nozaki3 (1. Dept. of Parasitol., Tokai Univ. Sch. of Med., 2. Dept. of Parasitol., Natl. Inst. Infect. Dis., 3. Dept. of Biomed. Chem., Grad. Sch. of Med., the Univ. of Tokyo)
[1P-251]Predictions of intrinsically disordered regions in rare proteins tend to vary among different predictors
○Hiroto Anbo1, Motonori Ota2, Satoshi Fukuchi1 (1. Maebashi Institute of Technology, 2. Nagoya Univ.)
[1P-252]Target-specific labeling/detectable peptide-type covalent bonding agents
○Koki Oginezawa1, Riku Katsuki1, Masumi Taki1 (1. The University of Electro-Communications)
[1P-253]Analysis of interaction sites in self-aggregation of CPEB3 involved in long-term memory formation
○Yujin Lee1, Harunobu Saito1, Motoharu Ueno2, Naotaka Sekiyama2, Masatomo So1, Ayako Furukawa1, Kenji Sugase1 (1. Kyoto Univ. Graduate School of Agricultural Science, 2. Kyoto Univ. Graduate School of Science)
[1P-254]Elucidation of the effects of post-translational modifications of a Mycobacterium tuberculosis dormancy regulator on the interaction with DNA Gyrase and its function
○Aoi Yoshino1, Takumi Fukuda1, Koki Watanabe1, Akihito Nishiyama2, Yuriko Ozeki2, Sohkichi Matsumoto2, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ., 2. Grad. Sch. of Medical and Dental Sci., Niigata Univ.)
[1P-255]A FIBRINOGEN-RELATED PROTEIN FROM Penaeus monodon, PmFREP CHARACTERIZATION
○Patcharin Wilasluck1,2, Pongsakorn Sukonthamarn1, Anchalee Tassankajon1, Kittikhun Wangkanont1,2 (1. Center of Excellence for Molecular Biology and Genomics of Shrimp, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand , 2. Center of Excellence in Molecular Crop, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand)
[1P-256]Structural and functional analysis of type I-B CRISPR-Cas effector from hyperthermophilic archaea Thermococcus kodakarensis
○Sumire Kitagawa1, Tomoyuki Numata1, Shunsuke Matsumoto1 (1. Dept. Biosci. & Biotech., Grad. Sch. Bioresour. & Bioenviron Sci., Kyushu Univ.)
[1P-257]Preparation and enzymatic characterization of long-type PL6 alginate lyase Aly85NT with quadruple mutation near the active site.
○Tatsuto Fujisawa1, Nanao Okimatsu1, Takaomi Nomura1 (1. Dept. Appl. Biol., Fac. Tex. Sci. Tech., Shinshu Univ.)
[1P-258]Significance of Rab3a ubiquitination by RNF115
○Tsubasa Tamaoki1, Toshiki Takahashi1, Hiroyuki Kawahara1 (1. Tokyo Metropolitan University)
[1P-259]Development of DARUMA, a prediction model for intrinsically disordered regions without using evolutionary information
○Itsuki Shimizu1, Takuya Ida1, Satoshi Fukuchi1, Hiroto Anbo1 (1. Maebashi Institute of Technology)
[1P-260]Identification and functional analysis of a novel oxidative stress response protein eIF6 by redox proteomics
○Daiki Kobayashi1, Masaki Matsumoto1 (1. Niigata University)
[1P-261]Analysis of the molecular conformational variations of α-Synuclein aggregates caused by mutations using electron microscope and Raman spectroscopy
○Masafumi Ohtsubo1, Yu Nagashima1 (1. Hamamatsu Univ Sch Med, Inst Photonics Med, Biomed Photonics Lab)
[1P-262]Antiviral response mediated by a novel domain of the type III CRISPR-Cas system
○Ryo Ouchi1, Yoshitomo Ito1, Shunsuke Matsumoto1, Tmoyuki Numata1 (1. Kyushu univ.)
[1P-263]Screening of PDZ domains targeted by virus proteins
○Takeshi Tenno1, Haruka Takagi1, Uiko Tomiyasu1, Hidekazu Hiroaki1,2 (1. Grad. Sch. Pharma. Sci., Nagoya Univ., 2. NU-COMIT)
[1P-264]Preparation and enzymatic characterization of novel alginate degradation enzyme, Alg43NT, belonging to Polysaccharide lyase family 38.
○Nanao Okimatsu1, Tatsuto Hujisawa1, Takaomi Nomura1 (1. Dept. Appl. Bio., Fac. Tex. Sci. Tech., Shinshu Univ.)
[1P-265(1AS-08-07)]The spatiotemporal proteome of cellulose-producing E. coli K-12 biofilms growing on agar
○Martin Robert1, Yukiko Fujino1,2 (1. Kyoto University, 2. Itochu Techno-Solutions)
[1P-266]Development of Photodynamic Therapy for Neovascular Age-Related Macular Degeneration Using Engineered Lipoprotein Nanoparticles
○Tatsuya Murakami1,2, Haruka Kurita1, Rumina Shima1, Reina Nakanishi1, Machiho Nishida1, Ryosuke Fukuda1, Ai Ichioka3, Kenji Suda3, Akitaka Tsujikawa3 (1. Toyama Pref. Univ., 2. iCeMS, Kyoto Univ., 3. Dept. of Ophthalmol. Vis. Sci., Kyoto Univ.)
[1P-267]Crystal structure analysis of PI5P4Kβ to reveal its GTP preference
○Miki Senda1, Koh Takeuchi2, Atsuo Sasaki3,4, Toshiya Senda1 (1. High Energy Accelerator Research Organization (KEK), 2. The University of Tokyo, 3. University of Cincinnati College of Medicine, 4. Keio University)
[1P-268]The role of sialic acid on cell-penetration of cell-penetrating peptides and proteins.
○Ken-Ichi Sano1,2, Yuta Nomata2 (1. Nippon Inst. Tech., 2. Grad. School, Nippon Inst. Tech.)
[1P-269]Verification of heat tolerance and function of aerobic metabolism-related proteins involved in high temperature adaptation of "Hot-spring frog", Buergeria japonica
○Yuka Asaeda1, Ogino Hajime1, Sambongi Yoshihiro2, Fujii Sotaro2, Igawa Takeshi1 (1. Hiroshima university Amphibian Research Center, 2. Hiroshima university Graduate School of Integrated Sciences for Life)
[1P-270]Force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring
○Nobumichi Takamatsu1,6, Hiroko Furumoto2, Takayuki Ariga3, Mitsuhiro Iwaki4,5, Kumiko Hayashi6 (1. Frontier Sciences, The Univ. of Tokyo, 2. Yamaguchi Univ., 3. Osaka Univ., 4. NICT, 5. IFReC, Osaka Univ., 6. ISSP, The Univ. of Tokyo)
[1P-271]Antigen Design for the Development of an Early-stage Breast Cancer Diagnosis Detecting Breast Cancer Patient-Specific Autoantibody Titres
○Airi Kinoshita1, Yusuke Sugii2, Youichi Takahama2, Tatsuya Ohashi2, Hiroyuki Takeda1 (1. PROS, Ehime Univ. , 2. Sysmex Corporation)
[1P-272]Development of a VHH Library towards Intrabody Applications
○Yuki Mochizuki1, Kanako Nakao1, Ryo Murakami1, Yasuhiro Matunaga2, Masayuki Tsuchiya1, Naoto Nemoto1,2 (1. Epsilon Molecular Engineering, Inc, 2. Graduate School of Sci. and Eng., Saitama Univ.)
[1P-273]Novel GPCR recombinant monoclonal antibodies for biomedical research
○Huong Thi Mai Nguyen1, Alexander Ball1, Yung Lin Hsieh1, Chun Kai Huang1, Sega Huang1, Shang Ru Wu1, Jiming Liu1, Po Shin Peng1, Chia Yi Lin1 (1. GeneTex, Inc.)
[1P-274]Visualizing co-translational folding pathway mediated by Molten-Globule (MG) state
○Yuichiro Konsihi1,2, Kanako Akamatsu3, Takehito Tanzawa2, Takayuki Kato2 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Institute for Protein Research, Osaka University, 3. Center for Advanced Modalities and DDS, Osaka University)
[1P-275]Enzymatic Lipidation Enhances the Antimicrobial Activity of Peptides
○Hikari Ozawa1, Azusa Miyata1, Sohei Ito1, Daisuke Fujinami1 (1. University of Shizuoka)
[1P-276]Evaluation of Antimicrobial Activity and Amyloidogenic Potential of Peptides Secreted by Bifidobacterium infantis
○Ayane Kumagai1, Sohei Ito1, Daisuke Fujinami1 (1. University of Shizuoka)
[1P-277]Prediction of the amino acid sequence of an unknown using the phylogenetic relationship of known species and its application to proteomics
○Nobuaki MIURA1,3, Tsuyoshi Tabata2, Yasushi Ishihama2, Shujiro Okuda3 (1. Nagoya University, 2. Kyoto University, 3. Niigata University)
[1P-278]Expression, purification, and cryo-EM structure analysis of the human Golgi-resident copper ion pump ATP7A
○QIAN XIAOLIN1, WATANABE SATOSHI2, KENJI INABA2 (1. Tohoku Univ., 2. Kyushu Univ.)
[1P-279]Development of a cell-selective protein delivery system using human IZUMO1-derived fusogenic peptides
○Shota Yamaguchi1, Rio Yamamoto1, Rikako Kato1, Kei Fujiwara1, Nobuhide Doi1 (1. Department of Biosciences and Infomatics, Keio University)
[1P-280]Integrated network analysis and enrichment analysis of proteome data obtained under different experimental conditions
○Manaka Nishizaki1, Shin Kawano2 (1. School of Science, Kitasato Univ., 2. School of Frontier Engineering, Kitasato Univ.)
[1P-281]Assessment of Metaproteome Data Analysis Methods Using a Mock Community and Their Application to the Japanese Gut Microbiota
○Ryota Fukumoto1, Yoshio Kodera1, Shin Kawano2 (1. School of Science, Kitasato Univ., 2. School of Frontier Engineering, Kitasato Univ.)
[1P-282]Attempts to Improve the Soluble Expression of Lipase from Burkholderia ubonensis in Heterologous Expression in Escherichia coli
○Shota Takinami Takinami1, Ryohei Ogawa2, Ayata Nakagawa2, Daisuke Fujinami1, Sohei Ito1 (1. Food Protein Engineering Laboratory, Department of Food and Nutritional Sciences, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 2. Polymer & Composite Materials Research Laboratory, Research & Development Division, Mitsui Chemicals, Inc.)
[1P-283]Analysis of RNA binding activity of Arl13b localized in primary cilia
○Yune Katsui1, Ikuko Yao1, Michinori Toriyama1 (1. Department of Biomedical Science, School of Biological and Environmental Sciences, Kwansei Gakuin University)
[1P-284]Unraveling WFS1 Selective Degradation through Proximity Labeling
○Grace Aprilia Helena1, Hiraku Tokuma1, Airi Inoue1, Tatsuya Niwa2, Hideki Taguchi2, Daisuke Sakano1, Shoen Kume1 (1. School of Life Science and Technology, Institute of Science Tokyo, Japan, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[1P-285]Single-cell glycome and transcriptome profiling of tumor microenvironment of pancreatic cancers
○Dinh Xuan Tuan Anh1 (1. University of Tsukuba)
[1P-286]Effects of rare sugars on proliferation of Entamoeba histolytica trophozoites in vitro
○Kentaro Kato1,2, Mitsumasa Miura1, Hiroshi Tachibana3, Ikuko Tsukamoto4 (1. Nekken, Nagasaki Univ., 2. TMGH, Nagasaki Univ., 3. Tokai Univ., 4. Kagawa Univ.)
[1P-287]Droplet-based glycan and RNA sequencing for profiling the distinct cellular glyco-states in single cells
○Sunanda Keisham1,2, Sayoko Saito 2, Satori Kowashi 2, Hiroaki Tateno1,2 (1. University of Tsukuba, 2. National Institute of Advanced Industrial Science and Technology)
[1P-288]Autonomous morphological control between lipid membrane vesicles and sheets
Wancheng Zhang1, Shutaro Takahasi1, Naohiko Shimada1, ○Atsushi Maruyama1 (1. Tokyo Institute of Technology)
[1P-289]Investigation of factor that inhibits the virulence of Streptococcus intermedius.
○Koyuki Toyoshima1, Toshifumi Tomoyasu2, Yoshiyasu Ishii3, Ai Fujimoto4, Atsushi Tabata2, Hideaki Nagamune2 (1. Div. Bioresour. Sci.Tokushima Univ., 2. Div. Biosci.&Bioindust., Grad. Sch. Tech., Indust.&Soc. Sci., Tokushima Univ., 3. Dept. Biosci.& Bioindust., Fac. Biosci.&Bioindust., Tokushima Univ., 4. R&D, Sunstar Inc.)
[1P-290]Development of the Pathway Analysis Environment "qpx" for Non-Model Organisms
○Ryo Nozu1,2, Naoya Oec3, Hidemasa Bono1,2 (1. Grad. Sch.Integ. Sci. Life, Hiroshima Univ., 2. Genome Editing Innovation Center, Hiroshima Univ., 3. Dogrun Inc.)
[1P-291]Regulation of metabolic pathway for N-Acetylglucosamine in Clostridium paraputrificum
○Nodoka Kuwahara1, Emi Kunitake1, Tetsuya Kimura1 (1. Mie Univ.)
[1P-292]Effects of high production of squalene on cell wall composition in Saccharomyces cerevisiae
○Ayu Joho1, Satoshi Kagiwada1 (1. Nara Women’s Univ.)
[1P-293]Direct observation of metabolism of supersulfides in a single cell: Raman microscopic study
○Keisuke Koga1, Shinji Kajimoto1, Shinya Tahara1, Tomohiro Konno1, Takakazu Nakabayashi1 (1. Grad. Sch. of Pharm. Sci., Tohoku Univ.)
[1P-294]Impaired peroxisome morphogenesis affects docosahexaenoic acid-phospholipid metabolism
○Yuichi Abe1,2, Yukio Fujiki3,4,5 (1. Fac. of Arts and Sci., Kyushu Univ., 2. Dept. of Biotech. and Life Sci., Sojo Univ., 3. Med. Inst. Bioreg., Kyushu Univ., 4. Inst. of Adv. Study, Kyushu Univ., 5. Grad. Sch. of Sci., Univ. Hyogo.)
[1P-295]Elucidation of the role of a2,6-sialylated O-glycans in renal glomerulus.
○Hiroyuki Izumi1,2, Sayaka Fuseya3, Yuka Murakami1,4, Yuno Seike1,2, Yuyu Shimizu1,5, Satoru Takahashi1, Takashi Kudo1 (1. Dept. Ana. Emb., Inst. Med., Univ. Tsukuba, 2. Mas. Pro. Med. Sci., Grad. Sch. Comp. Hum. Sci., Univ. Tsukuba, 3. Mol. Cell. Glyco. Res. Gro., Cell. Mol. Bio. Res. Inst., AIST, 4. Ph.D. Program in Human Biology, SIGMA, Univ. Tsukuba, 5. Coll of Med. Sci, Sch of Med and Health Sci, Univ. Tsukuba)
[1P-296]Integrated metabolomics and transcriptomics analysis of MBW-transcriptional complex in Marchantia polymorpha
○Akari Harada1, Haruka Arai2, Kazuya Yanagiura2, Kengo Morohashi1,2 (1. CIST, 2. TUS)
[1P-297]Isolation and omics analyses of cellulolytic bacteria, isolated from the Hokkaido University research forest.
○Saki Mitsumasu1, Naoki Hayashi2, Tatsuya Nagano1, Yoshinori Hasegawa3, Taichi Endo Takasuka1 (1. Hokkaido University, faculty of agri., 2. Hokkaido University, grad. sch. of agri., 3. Kazusa DNA Res. Inst.)
[1P-298]Methyl-end (ωx) desaturase diversifies biosynthetic capabilities of polyunsaturated fatty acids in bivalves
○Naoki Kabeya1, Marc Ramos-Llorens2, Yo Nakano1, André Gomes-dos-Santos3, Megumu Fujibayashi4, Juan C. Navarro2, L. Filipe C. Castro3, Yutaka Haga1, Óscar Monroig2 (1. Tokyo University of Marine Science and Technology, 2. Instituto de Acuicultura de Torre de la Sal (IATS), CSIC, 3. CIIMAR/CIMAR, University of Porto, 4. Kyushu University)
[1P-299]Elucidation of biosynthetic capability of polyunsaturated fatty acid in Solemya pusilla (Bivalvia, Protobranchia)
○Ai Iinuma1, Yo Nakano1, Naoki Kabeya1 (1. Tokyo University of Maine Science and Technology)
[1P-300]Phylogenetic Discordance in Aurantioideae: A Novel Read2Tree-Based Workflow for Unraveling Complex Evolutionary Histories
○Eranga Pawani Witharana1,2, Takaya Iwasaki3, Yukio Nagano1,2 (1. Analytical Research Center for Experimental Sciences, Saga University, Saga, Japan, 2. Graduate School of Advanced Health Science, Saga University, Saga, Japan, 3. Faculty of Science, Ochanomizu University, Tokyo,Japan)
[1P-301]Comprehensive search for human-specific duplicated genes
○Yosuke Nakano1, Ikuo Suzuki1, Kazuo Emoto1,2 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. International Research Center for Neurointelligence, The University of Tokyo)
[1P-302]Genome regulation of the scrambled genome of Oikopleura dioica
○Johannes Nicolaus Wibisana1, Charles Plessy1, Nicholas Luscombe1 (1. Okinawa Institute of Science and Technology)
[1P-303]Horizontal gene transfer between hosts and parasites of transposable elements in Anisakis
○Naoki Hoshino1, Hiroki Kuroda1,2 (1. Syst. Biol., Grad. Sch. of Med. And. Gov., Keio Univ. , 2. Env. Info., Keio Univ.)
[1P-304(1AS-16-02)]Variant calling in the era of accurate long reads: Challenges and perspectives posed by plant and animal genomes
○Yoshinori Fukasawa1,2 (1. Utsunomiya Univ. GRDC, 2. Utsunomiya Univ. C-Bio)
[1P-305]Utilization as a new microsynteny: Challenges in taxonomy using nuclear-mitochondrial sequence.
○Satoshi Inoue1, Kaori Ishikawa2, Kazuto Nakada2 (1. University of Tsukuba, Master's Program in Biology, 2. University of Tsukuba, Institution of Life and Enviromental Sciences)
[1P-306]Bioinformatics analyses of polyamine biosynthetic pathway of Thermus thermophilus
○Hinako Ikeshima1, Mirei Mabuchi2, Kei Yura1,2,3 (1. Grad. Sch. of Life Sci., Ochanomizu Univ., 2. Dept. Biology, Ochanomizu Univ., 3. Grad. Sch. of Biomedical Sci., Waseda Univ.)
[1P-307]Decrease in Purifying Selection Pressures on Wheat Homoeologous Genes: Tetraploidization vs Hexaploidization
○Akihiro Ezoe1, Motoaki Seki1 (1. RIKEN)
[1P-308]Analysis of Bacterial Community Structures Associated with the Pegmatites of the Wagu Mine in Fukushima Prefecture, Japan
○Hidetoshi Okajima1,2, Tomoro Warashina1,3, Asako Sato1, Akihiko Nishimura4, Yohey SUZUKI5, Akio Kanai1,2,3 (1. Institute for Advanced Biosciences, Keio University , 2. Faculty of Environment and Information Studies, Keio University, 3. Systems Biology Program, Graduate School of Media and Governance, Keio University, 4. Japan Atomic Energy Agency, 5. School of Science, University of Tokyo)
[1P-309]Allele-specific DNA methylation in Northern Pika IMPACT
○Miyuki Shindo1, Saki Aoto2, Ai Yamaguchi3, Tatsuo Oshida3, Kohji Okamura4 (1. Div. of Lab. Anim. Resour.,NCCHD, 2. Med. Gen. Ctr., NCCHD, 3. Lab. of Wildl. Biol., Obihiro Univ. of Agric. and Vet. Med., 4. Dept. of Sys. BioMed., NCCHD)
[1P-310(1AS-16-01)]Elucidating corporative evolution of genes and regulatory regions by employing massively parallel reporter assay
○Yuichiro Hara1,2, Naoko Yoshizawa-Sugata2, Toyoaki Natsume2, Ryoko Wada2, Atsushi Toyoda3, Hideya Kawaji2 (1. Kitasato Univ. Sch. Front. Eng., 2. Res. Ctr. Genome. Med. Sci., TMIMS, 3. NIG)
[1P-311]Molecular evolution of Oryzias sex-determining genes :hierarchical reversal evolution hypothesis for sex determination
○Shiori Inazumi1, Honoka Okuyama1, Momo Yamazaki2, Yusaku Ogita3, Kei Nakasako1, Shuuji Mawaribuchi4, Fuga Fujimura1, Shun Hayashi5, Daisuke Tsukamoto1,2, Takuya Matsuso1,2, Kei Tamura1,2, Michihiko Ito1,2 (1. Dept. of Biol. Sci. Grad. Sch. of Sci., Kitasato Univ., 2. Dept. of Sci., Sch. of Sci., Kitasato Univ., 3. Res. Cent. Integr. Evol. Sci., SOKENDAI, 4. Cell. Mol. Biotech. Res. Inst., AIST, 5. Amphibian Res. Center, Hiroshima Univ.)
[1P-312]Comprehensive analysis of tissue-specific gene regulation mechanisms in the SINE region via transcription factors
○yuki iwasaki1, Hidenori Nishihara2, Norihiro Okada1,3 (1. Nagahama Institute of Bio-Science and Technology, 2. Kindai University, 3. Kitasato University)
[1P-313]Verification of the ‘Jump-Corruption evolution’ hypothesis in the Sry sex-determining gene in therian mammals
○Honoka Okuyama1, Ayuka Tokunaga2, Shiori Inazumi1, Yusaku Ogita3, Shunsuke Iguchi2, Shuuji Mawaribuchi4, Shun Hayashi5, Kosuke Suda1, Daisuke Tsukamoto1,2, Takuya Matsuo1,2, Kei Tamura1,2, Michihiko Ito1,2 (1. Div. Biosci., Grad. Sch. Sci., Kitasato Univ., 2. Dept. Biosci., Sch. Sci., Kitasato Univ., 3. Res. Cent. Integr. Evol. Sci., SOKENDAI, 4. Cell. Mol. Biotech. Res. Inst., AIST, 5. Amphibian Res. Center, Hiroshima Univ.)
[1P-314]Construction of a Platform to Estimate Gene Expression quantity based on Whole Genome Data for understanding the Physiological Traits of Jomon People
○Tsubasa Suzuki1,2, Yoshiki Wakiyama2, Akiho Kuga2, Yusuke Watanabe2, Kae Koganebuchi2, Takafumi Katsumura3, Hajime Ishida4,5, Takafumi Ishida2, Jun Ohashi2, Hiroki Oota2, Masanori Imamura1,6,7 (1. Center for the Evolutionary Origins of Human Behavior, Kyoto University, 2. Graduate School of Science, The University of Tokyo, 3. Kitasato University School of Medicine, 4. Graduate School of Medicine, University of the Ryukyus, 5. Social Medical Corporation Ashinokai Mt.Olive Hospital, 6. Graduate School of Medical Sciences, Kanazawa University, 7. Evolution and Medicine Research Center, Kanazawa Universit)
[1P-315]Phylogenetic Distribution of Genes Related to Non-Ribosomal Protein Synthesis in Archaea
○Rei Abe1, Shohei Terazawa1, Kosuke Fujishima2,3 (1. LST., Science Tokyo, 2. ELSI., Science Tokyo, 3. Grad.sch. of Media and Governance., Keio Univ.)
[1P-316(1PS-16-03)]Circular DNA display: A novel technology for displaying expressed protein on circular DNA by in vitro transcription-translation
○Kenta Ichinoe1, Masayuki Su'etsugu1 (1. College of Science, Rikkyo University)
[1P-318]Protein synthesis from low concentration DNA using a reconstituted cell-free protein synthesis system (PUREfrex®)
○Takashi Kanamori1, Tomoe Fuse-Murakami1 (1. GeneFrontier Corporation)
[1P-319]Cell-Free Protein Synthesis System for Myosin Motor Proteins
○Daisuke Inoue1, Takeshi Haraguchi2, Koji Ito2 (1. Kyushu University, 2. Chiba University)
[1P-320]Selective enrichment of genetic information-carrying compartments based on their phospholipid composition in an icy environment.
○Tatsuya Shinoda1, Kazumu Kaneko2, Natsumi Noda3, Takayoshi Watanabe3,4, Yoshikazu Tanaka5, Yasuhito Sekine3, Tomoaki Matsuura3 (1. School of Life Sci and Tech., Tokyo Tech, 2. School of Earth and Planetary Sci., Tokyo Tech, 3. ELSI, Tokyo Tech, 4. School of Materials Sci., JAIST, 5. Graduate School of Life Sci., Tohoku Univ.)
[1P-321]Construction of Artificial Multicellular Structure with Alpha-hemolysin
○Xu Han1, Yuta Ishii1, Ako Kagawa2, Asako Narita2, Kota Naito3, Yoshikazu Tanaka3, Tomoaki Matsuura2 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. Earth-Life Science Institute (ELSI), Tokyo Institute of Technology, 3. Graduate School of Life Sciences, Tohoku University)
[1P-322]Biochemical Synthesis of Amino Acids Derived from PLA Plastics for Cell-Free Protein Synthesis
○I Tang1, Shota Nishikawa2, Po-Hsiang Wang3, Kosuke Fujishima2 (1. School of Life Science and Technology, Institute of Science Tokyo, Tokyo, Japan, 2. Earth-Life Science Institute, Institute of Science Tokyo, Tokyo, Japan, 3. Graduate Institute of Environmental Engineering, National Central University, Taoyuan, Taiwan)
[1P-323]Genetic analysis of Alpinia zerumbet native to the Nansei islands and development of its antiviral components
○Mari Narusaka1, Ken-Taro Sekine2, Kiyotaka Nagaki3, Yoshihiro Narusaka1 (1. RIBS Okayama, 2. Dept. of Subtrop. Agri., Grad. Sch. of Agri., Univ. of Ryukyus, 3. Inst. of Plant Sci. and Res., Okayama Univ.)
[1P-324]Analysis of proanthocyanidins from Alpinia zerumbet and minerals for controlling plant viruses
○Yoshihiro Narusaka1, Mari Narusaka1 (1. RIBS Okayama)
[1P-325]Pharmacokinetics-informed ADMET predictor for rational drug design
○Takuya Suzuoka1,2, Hirofumi Aso1, Daisuke Koga1, Hidesyuki Shimizu1,2 (1. Department of AI syatems medicine, M&D Data Science Center, Tokyo Medical and Dental University, 2. Graduate School of Medical and Dental Science, Tokyo Medical and Dental University)
[1P-326]Development of the novel heat stress-responsive gene analysis workflow utilizing public databases: implementation of meta-analysis and structural similarity search
○Sora Yonezawa1, Hidemasa Bono1 (1. Grad. Sch. Integ. Sci. Life, Hiroshima Univ.)
[1P-327]Verification of Moisturizing Effect and Skin Penetration Function of Cosmetic Base by Mass Spectrometry Imaging
○Reina Higashi1, Syown Tokoro1, Noriko Oshima 1, Ken Igawa1, Tadayuki Ogawa1 (1. Dokkyo Medical Univ.)
[1P-328]Developing the Gap Repair Cloning Method in Bacillus subtilis
○Shinya KANEKO1, Yasunori AIZAWA1,2 (1. Institute of Science Tokyo, 2. KISTEC)
[1P-329]Investigation of lipid nanoparticle Pharmacokinetics in Bombyx mori
○Tatsuya Ogawa1, Hiroaki Mon2, Shigehiro Ohdo3, Naoya Matsunaga3, Go Hirai4, Makoto Yoritate4, Takahiro Kusakabe2 (1. Laboratory of Insect Genome Science , Faculty of Bioresource and Bioenvironmental Sciences, Kyushu Univ., 2. Laboratory of Insect Genome Science , Faculty of Agriculture, Kyushu Univ., 3. Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kyushu Univ., 4. Department of Pharmaceutical Molecular Design, Faculty of Pharmaceutical Sciences, Kyushu Univ.)
[1P-330(1PS-15-08)]Development of omics technology for supersulfides and its application to drug discovery research
○Shingo Kasamatsu1,2, Ayaka Kinno1, Somei Komae1, Chiharu Miura1, Takuma Owaki1, Mahiro Kuryu1, Jun-ichi Hishiyama2, Tomoaki Ida3, Hideshi Ihara1,2 (1. Dept. of Biol. Chem., Grad. Sch. of Sci., Osaka Metropolitan Univ., 2. Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Prefecture Univ., 3. Org. for Res. Promo., Osaka Metropolitan Univ.)
[1P-331(1MS-06-03)]Spatial transcriptome analysis using photo-isolation chemistry
○Ryuichi Kimura1, Akinobu Suzuki2, Mizuki Honda3, Akihito Harada4, Kazumitsu Maehara4, Kaori Tanaka4, Toshiaki Furuta2, Yasuyuki Ohkawa4, Shinya Oki1 (1. Institute of Resource Development and Analysis, Kumamoto University, 2. Department of Biomolecular Science, Faculty of Science, Toho University, 3. Hirosima University Graduate School of Integrated Sciences, 4. Medical Institute of Bioregulation, Kyushu University)
[1P-332]Fusion of RNaseH1-interacting peptide and antisense oligonuleotide
○Natsuko Goda1, Yoshihiro Moai1, Saki Shimizu1, Takafumi Hosokawa1, Naori Tsurumi1, Sonoko Ishino2, Yoshizumi Ishino2, Takeshi Tenno1,3, Emi Hibino1, Tetsuya Kodama1,4, Hidekazu Hiroaki1,3,4 (1. Grad. Sch. Pharm. Sci., Nagoya Univ., 2. Dep. Biosci. and Biotec., Kyusyu Univ., 3. BeCellbar, LLC, 4. NU-COMIT)
[1P-333]Development of a platform for managing and publishing biological data
○Yusuke Azuma1, Masami Koike1, Jen-Chien Chang1, Shuichi Onami1 (1. RIKEN)
[1P-334]Development of a nucleic acid aptamer neutralizing dengue virus generated by VLP-SELEX and advanced in silico analyses
○Ryo Amano1, Akiya Michishita2, Kazumi Haga3, Ryota Nakano2, Akiko Ichinose2, Meng Ling Moi3, Michiaki Hamada2, Yoshikazu Nakamura4, Masaki Takahashi1 (1. The Institute of Medical Science, The University of Tokyo (IMSUT), 2. Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 3. Sch. of Int Health, Grad. Sch. of Med., Univ. of Tokyo, 4. RIBOMIC Inc.)
[1P-335]Recombinant protein production system using a vitamin B12-based blue-green photosensor
Kyohei Murakoshi1, Ryuta Noya1, Fukuda Madoka1, Tetsuya Yushina1, Kaichi Kitamura1, Manami Kobayashi1, ○Hideaki Takano1 (1. Nihon Univ.)
[1P-336]Effect of exercise intensity on expression of ROS-related genes
Chiharu Fujiwara1, Marina K Kon1, Shinichi Saitoh2, Yuji Takeda2, Hironobu Asao2, ○Hidetoshi Nara1 (1. Ishinomaki-Senshu Univ., 2. Yamagata Univ.)
[1P-337]Establishment of mammalian cells containing zebrafish chromosomes
○Yuzuki Hase1, Takahito Ohira1,2, Hiroyuki Kugoh1,2 (1. Dept. of Chr Bio Eng., Grad. Sch. of Med., Univ. of Tottori, 2. Chr. Eng. Res. Ctr., Univ. of Tottori)
[1P-338]Genomic stability analysis of zebrafish chromosomes in mammalian cells.
○Takahito Ohira1,2, Yuzuki Hase1, Hiroyuki Kugoh1,2 (1. Dept. of Chr Bio Eng., Sch. of Med., Univ. of Tottori, 2. Chr. Eng. Res. Cen., Univ. of Tottori)
[1P-339]SIN3A promotes hTERT mRNA transcription in human oral squamous cell carcinoma cells
○Haruka Ooi1, Miyu Murata2, Takahito Ohira1,3, Hiroyuki Kugo1,3 (1. Dept. of Chr Bio Eng., Grad. Sch. of Med., of Tottori , 2. Dept. of Chr Bio Eng., Sch. of Med., of Tottori , 3. Chr. Eng. Res. Cen., Univ. of Tottori)
[1P-340]Generation of Fragile X Syndrome Model Mice Using Chromosome Engineering Technology
○Ryouma Ichikawa1, Mizuki Ishikawa1, Rin Ushida4, Yuji Nakayama2,3, Hiroyuki Kugoh1,3 (1. Dept. of CBE., Grad. Sch. of Med. Sci., Tottori Univ., 2. RIC., Res. Init. & Promo., Tottori Univ., 3. CERC., Tottori Univ., 4. Sch. of Life Sci., Fac. of Med., Tottori Univ.)
[1P-341]Effects of morphological and mechanical properties of nuclei on neuronal function
○Yu Nagata1,2, Tanita Frey1, Koichiro Maki3, Taiji Adachi3, Yusuke Kishi2 (1. Grad. Sch. of Pharma. Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo, 3. Inst. of Life Med. Sci., Kyoto Univ)
[1P-342]Analysis for surviving cells appeared with induction of excision of centromeric DNA from a chromosome in Saccharomyces cerevisiae
○Hiroaki Matsuzaki1, Yuma Nakamura1, Sumire Shintani1 (1. Fukuyama University)
[1P-343]Hyperphosphorylation of nucleolar protein Nopp140 accelerates the mitotic disassembly of nucleolus.
○Hisashi Shimamura1, Shige H. Yoshimura2,3 (1. Kyoto Univ. Faculty of Integrated Human Studies, 2. Kyoto Univ. Graduate School of Biostudies, 3. Kyoto Univ. Center for Living Systems Information Science (CeLiSIS))
[1P-344]More constrained chromatin in oncogenic HRAS-transformed cells.
○Aoi Otsuka1,2, Katsuhiko Minami1,2, Koichi Higashi1,3, Akane Kawaguchi1,4, Sachiko Tamura2, Satoru Ide5, Michael J Hendzel6,7, Ken Kurokawa1,3, Kazuhiro Maeshima1,2 (1. Department of Genetics, School of Life Science, SOKENDAI, 2. Genome Dynamics Laboratory, National Institute of Genetics, 3. Genome Evolution Laboratory, National Institute of Genetics, 4. Molecular Life History Laboratory, National Institute of Genetics, 5. Tokyo Metropolitan Institute of Medical Science, Research Center for Genome Medical Science, 6. Department of Cell Biology, Faculty of Medicine and Dentistry, University of Alberta, 7. Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta)
[1P-345(1AS-13-04)]Understanding Micronuclei with Importin-α Enrichment
○Yoichi Miyamoto1, Shige H. Yoshimura2, Mutsumi Yokota3, Masato Koike3, Masahiro Oka4, Hisato Saitoh5, Toyomasa Katagiri1 (1. Lab. Biofunc. Mol. Med., Nat. Inst. Biomed. Innov., Health and Nutr., 2. Grad. Sch. Biostudies, Kyoto Univ., 3. Dept. Cell Biol. Neurosci., Grad. Sch. Med., Juntendo Univ., 4. Dept. Reg. Infect. Cancer, Res. Inst. Micrb. Dis., Osaka Univ. , 5. Faculty Adv. Sci. Tech. (FAST), Kumamoto Univ.)
[1P-346]Proteomics and genomics analysis of chromatin dynamics during cellular senescence
○Ohta Ohta1, Hideki Tanizawa1, Claire Yik-Lok Chung1, Hidetaka Kosako2, Ken-ichi Noma1,3 (1. Hokkaido University, 2. Tokushima University, 3. University of Oregon)
[1P-347]The molecular mechanisms of the CENP-T–Mis12C interaction in chicken DT40 cells, ensuring faithful chromosome segregation
○Yusuke Takenoshita1, Msatoshi Hara1, Reiko Nakagawa2, Mariko Ariyoshi1, Tatsuo Fukagawa1 (1. FBS, Osaka University, 2. BDR, RIKEN)
[1P-348]Analysis of the independent mechanism for loss of the expression plasmid of a heterologous stress protein in budding yeast
○Tatsuki Kenmochi1, Takesi Nakamoto2, Shiori Tobinaga1, Noriyuki Suka1,2 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Prog. in Chem. Life Sci., Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan)
[1P-349]Analysis of universal mitochondrial responses to acute aneuploidy and mechanisms of chromosome rearrangements
○Riku Kuse1, Yuko Ohno2, Kazufumi Hosoda3, Yoshino Kubota2, Kojiro Ishii1,2 (1. Grad. Sch. of Eng., Kochi Univ. of Tech., 2. Frontier Biosci., Osaka Univ., 3. CiNet, NICT)
[1P-350]SSX2 forms condensates with HP1 in nuclei
○Eika Kan1, Kazashi Kato2, Hiroaki Daitoku2, Koichiro Kako3, Yohei Miyanoiri4, Akiyoshi Fukamizu2, Kenji Iwasaki2,5 (1. Grad. Sch. Sci. Tech. Univ. of Tsukuba, 2. TARA, Univ. of Tsukuba., 3. ILES, Univ. of Tsukuba, 4. IPR, Osaka Univ., 5. QiLS, Univ. of Tsukuba.)
[1P-351]Phenotypic analysis of mis4-450, a temperature-sensitive mutant of fission yeast Mis4 required for G0 phase
○Michiko Suma1, Orie Arakawa2, Yuria Tahara2, Kenichi Sajiki3, Shigeaki Saitoh1, Mitsuhiro Yanagida2 (1. Institute of Life Science, Kurume University, 2. Okinawa Institute of Science and Technology Graduate University, 3. Illumina K.K)
[1P-352(1PS-06-05)]Artificial regulation of gene expression by triplex nucleic acid and triplex nucleic acid-binding proteins
○Hidetaka Torigoe1, Ryo Shinoda1, Maiko Shimmura,1, Kazuki Kiuchi1, Norihiro Sato1, Takuma Katayama1 (1. Tokyo University of Science)
[1P-353]Nucleolar stress response induced by anticancer drug stress in p53-deficient cells
○Takeru Torii1, Mako Sumida1, Miwako Kato Homma2, Junji Kawakami1, Daisuke Miyoshi1, Keiko Kawauchi1 (1. Konan Univ. FIRST, 2. Fukushima Med. Univ. Sch. Med.)
[1P-354]Spatiotemporal changes in the chromatin structure of artificial cell nuclei constructed in mouse oocytes
○Nao Yonezawa1, Tomoko Shindo2, Yasushi Hiraoka3, Tokuko Haraguchi3, Kazuo Yamagata1 (1. Kindai Univ., 2. Med., Keio Univ., 3. FBS., Osaka Univ.)
[1P-355]3D genomics by electron microscope tomography
Minggao Liang*1, Prashanti Jeyamohan*1, ○Saumya Agrawal1, Bruno Humbel2, Michiel de Hoon1 (1. Laboratory for Applied Computational Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2. Okinawa Institute of Science and Technology, Imaging Section, Okinawa, Japan)
[1P-356]Elucidation of Ca2+-PA signaling mechanisms that induce heat stress-dependent SAFB granule formation
○Yuji Furutani1, Kyohei Matono1, Mari Takahara1, Takashi Ohtsuki1, Kazunori Watanabe1 (1. Grad school of Interdis Sci and Eng in Health Sys, Okayama)
[1P-357]Title: Methods for Phase Separation Droplet Formation and Protein Interactions in Droplet Formation
○Norio Hirakawa1, Makoto Tsuzaki1, Yusuke Narita1, Masakazu Nakakubo1, Munetaka Isihiyama1 (1. Dojindo Laboratories)
[1P-358(1AS-06-03)]Analysis of Mammalian Autophagy Regulation Mechanism by Liquid-Liquid Phase Separation
○YUTA OGASAWARA1, ELIJAH W CALDWELL1, TAKUMA TSUJI1, YUTARO HAMA1, KAZUAKI MATOBA2, YUKO Fujioka1, Nobuo Noda1,2 (1. Institute for Genetic Medicine, Hokkaido University, 2. Institute of Microbial Chemistry (BIKAKEN))
[1P-359]Microscopic analysis of dynamics of proteins involved in Liquid droplet formation
○Yuki Sakurai1, Taro Mannen1, Toshiya Hayano1, Hiroyoshi Matsumura1 (1. Ritsumeikan Univ.)
[1P-360]ncRNA enhancer CR9 targeting biomarker genes in response to mechanical load on the heart
○Hyejin Jo1, Ken Matsuoka2, Osamu Tsukamoto3, Seiji Takashima2 (1. Dep. of Med. Biochem., Grad. of Front. Bio., Osaka Univ., 2. Dep. of Med. Biochem., Grad. of Med., Osaka Univ., 3. Dep. of Biochem., Hyogo Medical Univ.)
[1P-361]Morphological stress granule profiling using fluorescent-reporter cell library imaging under oxidative and osmotic stress
○PATRICK LOUIS LAGMAN HILARIO1, YUMA HANAI1, KATSUTOMO OKAMURA1 (1. Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology)
[1P-362]Hydroxyurea mitigates reductive stress in the endoplasmic reticulum of budding yeast
○Yuki Takano1, Kunio Nakatsukasa1 (1. Graduate School of Science, Nagoya City University)
[1P-363]The recruitment of 14-3-3 proteins to GPCRs is driven by different protein kinases.
○CARLOMARION CODOG CARINO1, Riku Kuwabara1, Kouki Kawakami1, Masataka Yanagawa1, Asuka Inoue1,2 (1. Grad Sch of Pharm Sci, Tohoku Univ, 2. Grad Sch of Pharm Sci, Kyoto Univ)
[1P-364]GDP-bound Rab27a regulates endocytosis in pancreatic beta-cells
○Soshiro Kodera1, Toshihide Kimura1, Tomohisa Ishikawa1 (1. university of shizuoka)
[1P-365]Quality control of amyloidogenic CsgA in the periplasm of E. coli
○Shinya Sugimoto1,2,3, Kunitoshi Ymanakaka4, Yuki Kinjo1,2 (1. Dept. Bacteriol., Jikei Univ. Sch. Med., 2. Cent. Biofilm Sci. Technol., Jikei Univ. Sch. Med., 3. Lab. Amyloid Reg., Jikei Univ. Sch. Med., 4. Dept. Mol. Cell. Biol., IMEG, Kumamoto Univ.)
[1P-366(1PS-15-09)]Interaction Analysis of Designable LNPs with Membrane-mimetic SUVs to Elucidate the Mechanism of Cell Tropism
○Kozue Furuya1, Shu Okumura1, Mitsuko Sugano1 (1. Toshiba Corporation)
[1P-367]Ectopic metabolic stress potentially induces autophagy
○Mayuko Hayashi1, Moeka Kawai1, Kunio Nakatsukasa1 (1. Nagoya City Univ.)
[1P-368]Autophagy promotes degradation of a plasma membrane ABC transporter in budding yeast
○Sayaka Nagano1, Mitsutaka Kubota1, Fan-Yan Wei2, Koji Okamoto1 (1. Grad. Sch. of Frontier Biosci., Osaka Univ., 2. IDAC, Tohoku Univ.)
[1P-369]Antifungal agent ε-poly-L-lysine inhibits the glycosylation of chitinase Cts1 in yeast.
○Kotaro Maruyama1, Kayo Ikeda1, Wataru Nomura2, Munenori Takehara3, Yoshiharu Inoue1 (1. Div. of Appl. Life Sci., Grad. Sch. of Agric., Kyoto Univ., 2. Grad Sch. of Agric., Shinshu Univ., 3. Sch. of Eng., Univ. of Shiga Pref.)
[1P-370]Exploration of flavonoids that inhibit melanosome transport and analysis of their molecular mechanisms
○Kumiko Kobayashi1, Michiko Kudo1, Masakatsu Kageyama1 (1. DHC Corporation)
[1P-371]Analysis of secretory pathway of newly synthetic proteins using the yeast RUSH system.
○Hiroki Shimamura1, Koya Nukaga1, Satoka Kondo1, Makoto Nagano2, Junko Toshima3, Jiro Toshima1 (1. Department of Biological Science and Technology, Tokyo University of Science, 2. Nat. Inst. of Infect. Dis. Center, 3. Sch. of Heal. Sci., Tokyo Univ. of Tech.)
[1P-372]Modification of recombinant protein N-glycan structure in cultured insect cells.
○Satoka Nagaoka1, Hiroaki Mon1, Masato Hino1, Akitsu Masuda1, Takeru Ebihara1, Jun Kobayashi, Takahiro Kusakabe1 (1. Kyushu University)
[1P-373]Development of a method to control ALS-related protein VAPB/VAP33 secretion in Drosophila
○Aoi Okumura1, Misako Okumura1,2, Takahiro Chihara1,2 (1. Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, Japan., 2. Program of Basic Biology, Graduate School of Integrated Sciences for Life, Hiroshima University, Japan.)
[1P-374]A novel regulation of nuclear proteostasis (protein homeostasis) by Mahjong(/DCAF1)
○Naoka Shiratsuchi1, Riku Egami2, Kei Kozawa1, Sakurako Nozaki1, Tomoki Kyo1, Yasuyuki Fujita1 (1. Kyoto University graduate school of medicine, 2. Institute for Genetic Medicine, Hokkaido University)
[1P-375]Deubiquitination of endosomal SNARE protein VAMP8 prevents the accumulation of the VAMP8-contained SNARE complex, possibly promoting VAMP8 priming and endosomal membrane fusion
○Marsya Yonna Nurrachma1, Yuzuka Nishioka1, Masayuki Komada1,2, Toshiaki Fukushima1,2 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[1P-376]Analysis of transcriptional and morphological regulation mechanisms during Golgi perturbation
○Hajime Tajima Sakurai1, Rei Tanaka1, Misako Kimura1, Hiyouga Tomioka1, Rukiya Hirase1, Kanae Sasaki1, Sadao Wakabayashi1, Kazufumi Hosoda3, Shigeomi Shimizu2, Hiderou Yoshida1 (1. Univ of Hyogo, 2. TMDU, 3. NICT)
[1P-377]Excessive accumulation of PI4P upon Golgi stress induces mitochondria-mediated apoptosis
○Marika Toide1, Yasuka Kawamoto1, Sadao Wakabayashi1, Hajime Tajima Sakurai1, Kanae Sasaki1, Hiderou Yoshida1 (1. Dept. of Mol. Biochem., Grad. Sch. of Sci., Univ. Hyogo)
[1P-378]Organelle dynamics at the conversion of intracellular structures in plant cells
○Toshiki Amari1,3, Noriko Nagata2, Masaki Ito1, Hirotomo Takatsuka1,4 (1. School of Biological Science and Technology, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan, 2. Faculty of Science, Japan Women's University, Bunkyo-ku, Tokyo 112-8681, Japan, 3. HaKaSe+ for WISE, JST, 4. PRESTO, JST)
[1P-379]Identificatoin of TRPML1 complex involved in lysosomal clustering using proximity labeling
○Shumpei Shimizu1, Yukiko Sasazawa1,2, Yoshiki Miura3, Shinji Saiki1,4, Nobutaka Hattori1,5 (1. Neurol., Fac. of. Med., Juntendo Univ. , 2. Res. Inst. Dis. of Old Age., Fac. of Med., Juntendo Univ. , 3. Biomed. Res. Core Fac. Juntendo Univ., 4. Dept. of Neurol., Inst. of Med. Univ. of Tsukuba, 5. RIKEN. CBS)
[1P-380]The molecular mechanisms of ER deformation and vesicle packet formation by host-viral Interaction
○Chiko Tokuda1, Takuma Ozaki1, Atsuko H. Iwane2,3, Takeshi Itabashi3, Toru Okamoto4, Yumi Itoh4, Shige H. Yoshimura1,5 (1. Grad.Sch.Biostudies, Kyoto Univ., 2. Res. Inst. for Cell Design Med.Sci., Yamaguchi Univ., 3. Biosystems Dynamics Research, Riken, 4. Sch. Med., Juntendo Univ., 5. Center for Living Systems Information Science (CeLiSIS), Kyoto Univ.)
[1P-381]Accurate Determination and Analysis of Calcium Concentration and Its Fluctuation in the Endoplasmic Reticulum and Golgi Apparatus4o
○Ryota Morikawa1,2, Shohei Fujii1, Sakura Ouchi3, Toshiaki Izawa4, Kenji Inaba1 (1. MIB, Kyushu Univ., 2. Graduate School of Life Sciences. Tohoku UniversityTohoku Univ., 3. Department of Chemistry. Faculty of Science. Tohoku Univ., 4. Graduate School of Science, University of Hyogo)
[1P-382]Selective autophagy of organelles during meiosis in S. pombe
○Mayu Tanimoto1, Yuya Kadowaki1, Haruka Uda1, Goji Miyasako2, Sayumi Yamashita1, Akio Nakashima1,2,3 (1. Animal Sci. Grad. Sch. Agric. Sci. Kobe Univ. , 2. Animal Sci. Facul. Agric. Kobe Univ., 3. Biosignal Res. Kobe Univ.)
[1P-383]High glucose inhibits endocytosis mediated by the small GTPase Rab5.
○Makoto Hagiwara1, Nagano Tadasato1, Matsushita Kenji2,3 (1. Univ. of Niigata Pref., Dep. of Health Nutr., 2. NCGG, Dep. of Oral Dis., 3. Ogaki Woman's College, Dep. Dental Hygiene)
[1P-384]Functional analysis of inner nuclear membrane protein Lamina-associated polypeptide 2 in West Nile virus infection
○Haruto Eguchi1, Keisuke Maezono1, Thammahakin Passawat1, Thuy Thi Ngoc Duong1, Kentaro Yoshii2, Hiroaki Kariwa1, Shintaro Kobayashi1,3 (1. Hokkaido Univ., Vet., P. Health, 2. Nagasaki Univ., CCPID, 3. Hokkaido Univ., IVReD)
[1P-385]A regulation of autophagy by potassium ion
○Natsu Matsumoto1, Yasuhiro Araki1, Takeshi Noda1 (1. Center for Frontier Oral Science, Osaka University Graduate School of Dentistry, Osaka, Japan)
[1P-386]Regulation of intracellular localization of catalase upon oxidative stress
○Kanji Okumoto1, Yukio Fujiki2,3,4 (1. Dept. of Biol., Fac. of Sci., Kyushu Univ., 2. Inst. for Adv. Study, Kyushu Univ., 3. Fac. of Arts and Sci., Kyushu Univ., 4. Univ. of Hyogo)
[1P-387]Mitochondrial dynamics in multiciliated cells of Xenopus epidermis
○Jihoon Kim1, Takayuki Teramoto1, Kanji Okumoto1, Eisei Matsui1, Yoshiyuki Anchi1, Arata Imamura1, Naho Okano1, Nobushige Nakajo1 (1. Grad. Sch. of Sys. Life Sci. Kyushu Univ.)
[1P-388]The mechanism for protecting cells from ER-membrane protein ngSeipin that causes motor neuron disease
○Shunsuke Saito1, Kazutoshi Mori1 (1. Kyoto University Institute for Advanced Study, KUIAS)
[1P-389]Regulatory mechanisms and physiological roles of meiosis-specific autophagy
○Yuya Kadowaki1, Mayu Tanimoto1, Haruka Uda1, Sayumi Yamashita1, Akio Nakashima1,2 (1. Animal sci. Grad. Sch. of Agric. Sci., Kobe Univ., 2. Biosignal Res., Kobe Univ.)
[1P-390]Coxfa4l3, a subunit protein of the mitochondrial electron transport chain Complex IV, enhances sperm motility
○Kosei Oishi1, Reiji Tokito1, Tomoya Sugiyama1, Manabu Yoshida2, Kaoru Yoshida3, Tsuyoshi Koide4, Yasuyuki Kurihara1 (1. YOKOHAMA National Univ., 2. TOKYO Univ., 3. Toin Univ. of YOKOHAMA, 4. National Institute of Genetics)
[1P-391]Regulation of intracellular iron dynamics by mitochondrial function and quality control
○Atsushi Tanaka1,2, Natsuki Toyoshi1,9, Tsuyoshi Usami1,9, Izumi Yanatori3, Maho Hamasaki4, Taiki Baba5, Kohsuke Takeda5, An-Chi Wei6, Chuang-Rung Chang7, Heidi M McBride8 (1. Grad. Sch of Med., Yamagata Univ., 2. Res. Inst. of Med. Sci., Dept. of Med., Yamagata Univ., 3. Grad. Sch of Med., Kyoto Univ., 4. Grad. Sch of Med., Osaka Univ., 5. Grad. Sch of Biomed. Sci, Nagasaki Univ., 6. Dept. of Elec. Engr., Natl. Taiwan Univ., 7. Dept. of Med. Sci., Natl. Tsing Hua Univ., 8. Neuro Inst., McGill Univ., 9. Dept. of Med., Yamagata Univ.)
[1P-392]Methyl rosmarinate: a natural product, specifically activates the IRE1-XBP1 pathway
○Takashi Miyazaki1, Kan Sato2, Shinichi Yonekura1, Yukako Tokutake1 (1. Shinshu Univ., 2. Tohoku Univ.)
[1P-393]Mitofissin, a novel mitochondrial fission factor, divides mitochondria by cooperating with Dnm1
Kentaro Furukawa1, Manabu Hayatsu2, Kentaro Okuyama2, Shinsuke Shibata2, ○Tomotake Kanki1 (1. Kyushu University, 2. Niigata University)
[1P-394]Imaging mitochondria-ER contact sites with split-FAST based probes
○Satoko Shinjo1,2, Aurelia Miscia1,2, Luca Scorrano1,2 (1. University of Padua, 2. Veneto Institute of Molecular Medicine (VIMM))
[1P-395]Mode of action of lysine for the translocation of transporters into vacuoles
○Natsumi Ozaka1, Yoshika Tanoue2, Nami Murao1, Nodoka Hamada2, Haruto Nakajo1, Miyuki Kawada1,3,4, Takayuki Sekito1,3 (1. Grad. Sch. of Agr., Ehime Univ., 2. Fuc. of Agr., Ehime Univ., 3. PROS, Ehime Univ., 4. ADRES, Ehime Univ.)
[1P-396]Comprehensive screening of alanine-substitution mutants for elucidation of Drosophila epithelial cadherin binding mode
○Masayuki Niwa1,2, Hiroki Oda1,2 (1. JT Biohistory Research Hall, 2. Osaka Univ.)
[1P-397]Nanoscale visualization of Drosophila E-cadherin ectodomain fragments and their interactions using DNA origami nanoblocks
○Hiroki Oda1,2, Shigetaka Nishiguchi3, Chihong Song3,4,5, Kazuyoshi Murata3,4,5, Takayuki Uchihashi3,6, Yuki Suzuki7 (1. JT BRH, 2. Osaka Univ., 3. ExCELLS, 4. NIPS, 5. SOKENDAI, 6. Nagoya Univ., 7. Mie Univ.)
[1P-398(1PS-15-10)]Development of brain-targeting drug delivery system using small molecules that transiently control blood-brain barrier
○Saito Inoue1, Atsuya Shirono1, Jumpei Taguchi2, Satomi Tomita2, Takamitsu Hosoya2, Hiroyuki Takeda3, Keisuke Tachibana1, Masuo Kondoh1,4, Yasushi Fujio1,4, Yoshiaki Okada1,4 (1. Grad. Sch. Pharm. Sci., Osaka University, 2. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 3. PROS, Ehime University, 4. Center for Infectious Disease Education and Research (CiDER), Osaka University)
[1P-399]Analysis of Actin Dynamics Rerated to the Reversible Direction Change of Neural Migration(Kibisu-gaeshi)
○Wakana Terao1,2, Katsutoshi Mizuno1,3, Ryodai Katoh1,4, Takafumi Itoh2, Satoshi Fujita3,4, Masami Yamada1,3 (1. Univ of Fukui school of Med., 2. Fukui Prefectural Univ. , 3. Research and Education Program for Life Science,University of Fukui., 4. Univ of Fukui school of Engineering)
[1P-400]Functional analysis of plant-derived functional components targeting fibrosis-related diseases
○Hikaru Koyama1, Takumi Iwasawa2, Kazunori Kato1 (1. Dept. Nutrition Sci., Health and Sports Sci., Toyo Univ, 2. Institution of Life Innovation Research Center, Toyo Univ)
[1P-401]Analysis of epithelial barrier abnormality via IL-22 signaling by using Caco-2 2.5D culture model
○Takumi Konno1, Maki Miyakawa2,1, Shin Kikuchi3, Tomoki Sugiyama1, Yuya Yamazaki1, Takayuki Kohno1, Hiroki Tanaka2, Takashi Kojima1 (1. Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, 2. Sapporo IBD Clinic, 3. Department of Anatomy(1), Sapporo Medical University School of Medicine)
[1P-402]Radiation-induced transcription and post-transcriptional regulation of type V collagen
○Mami Yano1,2, Hiroyuki Yano1,3, Ryoji Hamanaka4, Mariko Hida5, Hidekatsu Yoshioka1,6, Noritaka Matsuo1 (1. Department of Matrix Medicine, Faculty of Medicine, Oita University, 2. Nippon Bunri University Medical College, 3. Department of Radiological Science, Faculty of Health Sciences, JUNSHIN GAKUEN University, 4. Department of Human Sciences, Oita University of Nursing and Human Sciences, 5. Institute for Research Management, Oita University, 6. Department of Clinical Examination, Shinbeppu Hospital)
[1P-403]Cell behaviors within a confined adhesive area fabricated using novel micropatterning methods
○Shigehiko Shigehiko Yumura1, Tsukasa Nakatoh1, Takuji Osaki2, Sohma Tanimoto1, Md. Golam Sarowar Jahan3,1, Tomohisa Kawakami2, Kentaro Chihara2 (1. Yamaguchi University, 2. Shoyo Sangyo Co., Ltd, 3. University of Rajshahi)
[1P-404]Aging Analysis of C. elegans Type XVIII Collagen/CLE-1 by Using Endostatin Deficient Mutant and Isoform-specific Feeding RNAi Treatments
○YUNXIN YE YE1, Masahiro Ito1, Yukihiko Kubota1 (1. Information biology lab)
[1P-405]Inhibition of tricellular tight junction formation, a three-cell adhesion structure, promotes the migration and invasion of epithelial cancer cells
○Daiki Nakatsu1, Takashi Tsunoda2, Masayuki Murata1,3, Fumi Kano1 (1. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, 2. Department of Life Science and Technology, School of Life Science and Technology, Institute of Science Tokyo, 3. Multimodal Cell Analysis Collaborative Research Cluster, Institute of Science Tokyo)
[1P-406]Pharmacological effect of flavonoids in cherry bark extract on epithelial tight junctions.
Yuri EMOTO1, Mio NAKASHIMA1, Kouki OKADA4, Emi HIBINO1, Natsuko GODA1, Takeshi TENNO1,3, ○Hidekazu Hiroaki HIROAKI1,2,3 (1. Grad. Sch. Pharm. Sci.. Nagoya Univ. , 2. NU-COMIT, 3. BeCellBar, LLC., 4. Dept. Biol, Sch. Sci., Nagoya Univ.)
[1P-407]clustered protocadherins-mediated extracellular and intracellular protein interactions determine the survival fate of neurons in central nervous system
○Ryuon Higuchi1, Tatsuaki Ueno1, Masahiko Watanabe2, Makoto Sanbo3, Masumi Hirabayashi3, Takeshi Yagi1 (1. KOKORO Biology Group, FBS, Osaka Univ., 2. Department of Anatomy and Embryology, Grad. Sch. of Med., Hokkaido Univ., 3. Section of Mammalian Transgenesis, Center for Genetic Analysis of Behavior, NIPS)
[1P-408]The role of long non-coding RNA (lncRNA) in osteoblasts differentiation
○Hiroyuki Yano1,2, Mami Yano2,5, Ryoji Hamanaka3, Mariko Hida2, Noritaka Matsuo2, Hidekatsu Yoshioka2,4 (1. Department of Radiological Science, Faculty of Health Sciences, JUNSHIN GAKUEN University, 2. Faculty of Medicine, Department of Matrix Medicine, Oita University, 3. Department of Human Sciences, Oita University of Nursing and Human Sciences, 4. Department of Clinical Examination, Shinbeppu Hospital, 5. Nippon Bunri University MEDICAL COLLEGE)
[1P-409]The role of regulation of src family tyrosine kinase activities in morphological changes during neuronal maturation.
○Shiho Ito1, Yoshiaki V Nishimura2, Takeshi Kawauchi1,3 (1. Dept. Adaptive & Maladaptive Responses in Health & Dis., Grad. Sch. of Med., Kyoto Univ., 2. Div. Neurosci., Tohoku Med. and Pharm. Univ., 3. Dept. Physiol., Keio Univ. Sch. of Med.)
[1P-410]Generation of Sorbs1(CAP) and Sorbs2(ArgBP2) knockout medaka involved in mechanosensing
○Kentaro Kawai1, Sakurako Nozaki1, Takashi Yamanaka2, Yasuhisa Kimura1, Masato Kinoshita2, Noriyuki Kioka1 (1. Kyoto university graduate school, 2. Kyoto Univ.)
[1P-411]Investigation of metal ion dependence in organic sulfur compound-responsive human odorant receptors
○Yumika Ono1, Haruka Saito1, Masashi Abe1, Masafumi Yohda1, Yosuke Fukutani1 (1. Dept of Biotechnol., Tokyo Univ. of Agric and Technol)
[1P-412]Elucidation of the regulatory mechanisms of endothelial cell barrier function involved in the pathophysiology of depression
○Kana Tominaga1, Norihiro Yamada1, Naoomi Tominaga2, Shin Nakagawa1 (1. Div. Neuropsychiatry, Yamaguchi Univ., 2. Div. Clinical Laboratory Sciences, Yamaguchi Univ.)
[1P-413]Analyzing effects of ZO-1 localization changes on cell competition
○Asayuki Kitajima1,2, Sayuki Hirano2, Kazuhiro Aoki2 (1. Kyoto Univ. Science. Biological Sciences., 2. Kyoto Univ. Biostudies.)
[1P-414]Heparan sulfate proteoglycans are dynamically involved in the regulation of planar cell polarity in cooperation with core PCP components and Wnt11
○Minako Suzuki1,2,3, Ritsuko Takada2,3, Shinji Takada2,3, Yusuke Mii1,2 (1. Kyoto Univ., 2. NIBB, 3. ExCELLS)
[1P-415]The Study of Morphological and Functional Changes in Fibroblasts via ex vivo 3D Culture Using a Decellularized Mouse Lung Scaffold-based Recellularization Model
○Chihiro Inoue1, Takaya Suzuki2, Saori Shibata2, Takayasu Ito2, Yasuhiro Miki1, Yoshinori Okada2, Takashi Suzuki1 (1. Dept. Anat. Pathol., Tohoku Univ. , 2. Thorac. Surg., IDAC., Tohoku Univ.)
[1P-416]Elucidation of the Regulatory Mechanism of Lipid Raft Dynamics by ABCG1 Palmitoylation
○Yuto Yamanaka1, Shuhei Osaka1, Takuya Kato1, Hiroyuki Kusuhara1, Hisamitsu Hayashi1 (1. Univ. Tokyo)
[1P-417]The antifungal agent micafungin inhibits nuclear fusion during mating of Saccharomyces cerevisiae
○Nanami Kobayashi1, Ohya Yoshikazu2, Itami Kenichirou3, Satou Ayato3, Nishikawa Shuichi4 (1. Grad. Sch. Sci. Tech., Niigata Univ, 2. Grad. Sch. Front. Sci, Univ. Tokyo, 3. Grad. Sch. ITBM., Nagoya Univ, 4. Fac. Sci. Niigata Univ)
[1P-418]Functional analysis of microtubule binding protein Tppp3 in mouse trachea
○Sohshiroh Atsumi1, Takahumi Sakai1, Katsuyoshi Takaoka2, hiroshi hamada3, Kyosuke Shinohara1 (1. University of Tokyo University of Agriculture and Technology, 2. Tokushima University, 3. Institute of Physical and Chemical Research)
[1P-419]Signal regulation of AT1R by TRPV4 through plasma membrane remodeling
○Kota Shimizume1, Ryoji Kise1, Masataka Yanagawa1,2, Asuka Inoue1,3 (1. Grad. Pharm. Sci., Tohoku Univ., 2. RIKEN CPR, 3. Grad. Pharm. Sci., Kyoto Univ.)
[1P-420]Tppp3 regulates basal body position and ciliary membrane composition of airway motile and sensory cilia via microtubule assembly
○Takafumi Sakai1, Sohshiroh Atsumi1, Katsuyoshi Takaoka2, Misaki Kurata1, Hiroshi Tsugawa1, Hiroshi Hamada3, Kyosuke Shinohara1 (1. Tokyo university of aguriculture and technology, 2. Tokushima University , 3. RIKEN)
[1P-421]Analysis of protein methylation in cilia and flagella
○Katsutoshi Mizuno1, Natsumi Mizuno2, Tomohiro Kubo3, Kogiku Shiba4, Kazuo Inaba4, Makoto Orisaka2, Masami Yamada1 (1. Univ. of Fukui, Dept. of Med. Biochemistry, 2. Univ. of Fukui, Dept. of Med. Obstetrics-Gynecology, 3. Univ. of Yamanashi, Dept. of Med., 4. Univ. of Tsukuba, Shimoda Marine Research Center)
[1P-422]Solo regulates PDZ-RhoGEF to remodel actin cytoskeleton in response to substrate stiffness
○Aoi Kunitomi1, Shuhei Chiba1, Nahoko Higashitani2, Atsushi Higashitani2, Kensaku Mizuno1, Kazumasa Ohashi1 (1. Mol. Cell. Biol., Grad. Sch. of Life Sci., Tohoku Univ., 2. Mol. Genet. and Physiol., Grad. Sch. of Life Sci., Tohoku Univ.)
[1P-423(1PS-02-04)]Assembly mechanisms of tardigrade-unique cytoskeleton CAHS
○Akihiro Tanaka1, Yuta Shimamoto1 (1. National Institute of Genetics)
[1P-424]Detection of Biomolecule-Binding Microparticles by Single-Particle Inductively Coupled Plasma Mass Spectrometry: Towards the Development of High-Performance Biomolecular Carriers
○Eriko Fukuda1, Shin-Ichi Miyashita2, Toshihiko Ogura3, Shun-Ichi Matsuura4, Toshiyuki Takagi1 (1. AIST CMB, 2. AIST NMIJ, 3. AIST HMRI, 4. AIST CPT)
[1P-425]LAT1 amino acid transporter supports mitosis through the regulation of Golgi unlinking
Sakura Yanagida1, ○Ryuzaburo Yuki1, Youhei Saito1, Yuji Nakayama1 (1. Kyoto Pharmaceutical Univeristy)
[1P-426]Dissecting the mechanistic links between cell chirality and chiral actin fibers formed by class I myosins
○Daiki Kitamura1, Haruna Nishikawa1, Mikiko Inaki1, Kenji Matsuno1 (1. Department of Biological Sciences, Graduate School of Science, Osaka University)
[1P-427]Cytoskeletal segmentation method using deep learning
○Ryota Horiuchi1, Takumi Higaki1 (1. Kumamoto Graduate School Master's Program)
[1P-428]Comprehensive specificity analysis of actin-regulatory proteins, RhoGEF
○Mizuho Ito1, Yutaro Nagasawa1, Hideji Murakoshi1 (1. National Institute for Physiological Sciences)
[1P-429]Exploring the dynamics and function of FGD family proteins as potential activators of Cdc42 during synaptic plasticity
○Yutaro Nagasawa1,2, Kayo Hirata1, Sayaka Iida1, Hideji Murakoshi1,2 (1. Supportive Center for Brain Research, National Institute for Physiological Sciences, 2. Department of Physiological Sciences, SOKENDAI (The Graduate University for Advanced Studies))
[1P-430(1MS-02-04)]Optogenetic control of p53 signaling pathway
○T Tsuruoka1,2,3,4, Yuhei Goto1,2,3,4, Kazuhiro Aoki1,2,3,4 (1. Laboratory of Cell Cycle Regulation, Graduate School of Biostudies, Kyoto University, 2. Quantitative Biology Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 3. Division of Quantitative Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 4. Department of Basic Biology, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies))
[1P-431(1AS-08-06)]Code-switching: the mechanism of multicellular/unicellular plasticity in black yeast
○Gakuho Kurita1, Kazuma Uesaka2, Gohta Goshima1 (1. Nagoya University, Graduate School of Science, 2. Nagoya University Center for Gene Research)
[1P-432]CENP-C is involved in maintenance of centromeric chromatin via direct interaction with HJURP
○Yutaka Mahana1, Tetsuya Hori1, JingHui Cao1, Mariko Ariyoshi1, Tatsuo Fukagawa1 (1. Osaka Univ.)
[1P-433]How Plk1 activity is regulated by conformational transition
○Chang Liu1,2, Motoko Takahashi1, Toru Hirota1 (1. JFCR, Cancer Institute, 2. TUS, Tokyo University of Science)
[1P-434]Transcriptome-wide profiling for immortalized melanocytes derived from new born and adult human epidermis
○Ai Orimoto1, Sayo Kashiwagi2, Ayaka Funakoshi2, Takashi Shimizu2, Tsuyoshi Ishii2, Chiaki Kitamura1, Tohru Kiyono3, Tomokazu Fukuda4 (1. Kyushu Dental University, 2. Rohto Pharmaceutical Co, 3. National Cancer Center, 4. Iwate University)
[1P-435]The functional analysis of long noncoding RNAs that are involved in the regulation of cell proliferation
○Hikari Ikenaga1, Yoshinobu Tanigawa1, Ryoka Tarumi1, Yojiro Kotake1 (1. Kindai Univ.)
[1P-436]Characterization of kinetochore organization in Dictyostelium discoideum
○Natsumi Yamaguchi1, Shreyas Sridhar1, Mariko Ariyoshi1, Tatsuo Fukagawa1 (1. Osaka University)
[1P-437]Budding yeast 14-3-3 protein contributes to the accurate initiation timing of S phase
○Nozomi Gotouda1, Shiho Ogawa3, Seiji Tanaka1,2 (1. Grad. Sch. Eng., Kochi Univ. Tech., 2. Sch. Env. Sci. Eng., Kochi Univ. Tech., 3. Sch. Biol. Env. Sci., Kwansei Univ.)
[1P-438]Aurora A plays a role in the detachment of kinetochores from microtubules in anaphase
○Kenji Iemura1, Yuriko Ikezawa1, Kozo Tanaka1 (1. Dept. Mol. Oncol., IDAC, Tohoku Univ.)
[1P-439]Mechanistic analysis on the regulating mammalian cell proliferation through 5-ALA metabolic pathway
○Seiya Watanabe1, Taku Chibazakura1 (1. Dept. of Biosci., Grad. Sch. of Life Sci., Tokyo Univ. of Agric.)
[1P-440]An “in schizo” evaluation system to screen for human kinesin-5 and kinesin-12 inhibitors
○Fara Difka Afdilla1, Masashi Yukawa1,2 (1. Grad. Sch. of Integ. Sci. for Life, Hiroshima Univ., 2. HiHA, Hiroshima Univ.)
[1P-441]Mechanisms of intracellular temperature change using fluorescent nanodiamonds
○Risa Ujiie1, Kiichi Kaminaga1, Chihiro Suzuki1, Satomi Yanagihara1, Keiji Suzuki2, Hiroyuki Abe3, Takeshi Ohshima3, Ryuji Igarashi1 (1. QST, Institute for Quantum Life Science, 2. Atomic Bomb Disease Institute, Nagasaki University, 3. QST, Quantum Materials and Applications Research Center)
[1P-442]CENP-E orientation in fibrous corona defined by expansion microscopy
○Hirotaka Fukue1, Kenji Iemura1, Kozo Tanaka1 (1. Dept. of Mol. Oncol., IDAC, Tohoku Univ.)
[1P-443]Suppression of cell proliferation induced by nucleolar localized Neu4 via the interaction with RPL11 and RPL5
○Toshiki Hyodo1, Satsuki Yamate2, Xiaoyinging Chen2, Masaharu Komatsu1,2,3, Kazuhiro Shiozaki1,2,3 (1. Unit. Grad. Sch. of Agricult. Sci., Kagoshima Univ, 2. Food Innovation Sci., Grad. Sch. Agricult. Forest. Fish., Kagoshima Univ., 3. Food Life Sci, Fac.Fish., Kagoshima Univ)
[1P-444]Cell fate conversion and unique cell division triggered by cell fusion
○Joey Nakane1,2, Taisei Kumazaki2, Chinatsu Yonekawa2, Tomomi Tsubouchi1,2 (1. SOKENDAI, 2. National Institute for Basic Biology)
[1P-445]Toward elucidating intracellular temperature changes induced by ionizing radiation using fluorescent nanodiamond NVC
○Kiichi Kaminaga1, Risa Ujiie1, Chihiro Suzuki1,2, Keiji Suzuki3, Hiroshi Abe4, Takeshi Ohshima4, Ryuji Igarashi1,2,5 (1. IQLS, QST, 2. Graduate School of Science and Engineering, Chiba Univ., 3. Atomic Bomb Disease Institute, Nagasaki Univ., 4. Takasaki Institute for Advanced Quantum Science, QST, 5. Dept. of Life Science and Technology, TITEC)
[1P-446]Analysis of the relationship between S-adenosyl methionine metabolism and ribosome biogenesis in Bacillus subtilis
○Natsuki Osaka1, Kei Asai2, Kan Tanaka1 (1. Lab. Chem. Life. Sci., Tokyo Inst. Tech., 2. Dept. Biosci., Tokyo Univ. Agric.)
[1P-447]Effects of fluorocarbon solvents on stresses and growth of bacteria
○Ryosuke Hosoki1, Koji Kawada1, Katsuaki Izawa1, Keita Saito1, Yoshihisa Yamashige2, Shojiro Kikuchi3, Yuichi Ogawa2, Masahiko Harata1 (1. Grad. Sch. Agri. Sci., Tohoku Univ., 2. Grad. Sch. Agri. Sci., Kyoto Univ., 3. Inst. Adv. Med. Sci., Hyogo Med. Univ.)
[1P-448]Genome-wide gene knockout screening to explore the regulatory mechanisms of amino acid and glucose metabolism in cells.
○Ohkubo kiichi1, Hiroyuki Iwata1, Shusaku Shibutani1 (1. Yamaguchi univercity)
[1P-449]The Odf2 status is involved in asymmetric inheritance of CD133-positive recycling endosomes during cytokinesis in SK-N-DZ human neuroblastoma cells
○Hideki Izumi1 (1. Medical Research Institute, Saga Medical Center)
[1P-450]Exploration of Cardiac Regeneration Factors Using a Ubiquitin Ligase Library
○Kazuki Nakahara1, Hashim Ali2, Mateusz Tomczyk1, Mauro Giacca1 (1. School of Cardiovascular and Metabolic Medicine & Sciences and British Heart Foundation Centre of Research Excellence, King’s College London, London, United Kingdom, 2. Division of Infection and Immunity, University College London, London, United Kingdom)
[1P-451]PRMT5-mediated methylation of STAT3 is required for lung cancer stem cell maintenance and tumour growth
○Yoshinori Abe1,2, Takumi Sano2, Naoki Otsuka2, Masashi Ogawa2, Nobuyuki Tanaka2,3 (1. Lab. Mol. Anal., Nippon Med. Sch., 2. Div. Mol. Oncl., Isnt. Adv. Med. Sci., Nippon Med. Sch., 3. Kobe Univ.)
[1P-452]Analysis of the mechanism of drug and insulin-responsive mTOR complex formation using mLST8 as an indicator
○Suzuno Hirano1, Kohdai Yamada1, Kohei Nishino2, Hidetaka Kosako2, Tatsuya Sawasaki1 (1. Proteo-Science Center, Ehime University, 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
[1P-453]Identifying the role of ubiquitination in lipid asymmetric signaling at the plasma membrane.
○Ayumi Soya1, Kouhei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Dept. of Biol. Sci., Grad. Sch. of sci., Nagoya Univ)
[1P-454]Phospho-regulation of the actin-binding protein cortactin by mitochondrial protein phosphatase PGAM5 during mitophagy
○Susumu Tanimura1, Mizuki Arita1, Akimi Inoue1, Taiki Baba1, Jun Takouda1, Kohsuke Takeda1 (1. Nagasaki Univ.)
[1P-455]p38 augments TAB1 tyrosine phosphorylation via Src activation
○Iimi Onuma1, Yusuke Iwata1, Mai Nakada1, Hiroyuki Iwahara1, Kanako Natori1, Arisa Kondo1, Yue Zhou1, Satoru Yokoyama1, Tatsuhiko Ozawa2, Kiyonao Sada3, Hiroaki Sakurai1 (1. Department of Cancer Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2. Department of Life Sciences and Bioengineering, Faculty of Engineering, University of Toyama, 3. Department of Genome Science and Microbiology, Faculty of Medical Sciences, University of Fukui)
[1P-456]Non-canonical phosphorylation of vascular endothelial growth factor-3 (VEGFR-3)
○Masaya Yamane1, Yue Zhou1, Atsushi Takashima1, Akane Yamada1, Takeshi Masuda2, Satoru Yokoyama1, Hiroaki Sakurai1 (1. Cancer Cell Biol., Univ. of Toyama, 2. IAB, Keio Univ.)
[1P-457(1AS-06-07)]Structural basis of ubiquitin chain selectivity by TAX1BP1 in mitophagy
○Akinori Okamoto1, Kei Okatsu1, Shuya Fukai1 (1. Department og Chemistry, Graduate School of Science, Kyoto University)
[1P-458]Molecular mechanisms of CaMKK oligomerization
○Shun Uenoyama1, Hayato Nitta2, Satomi Ohtsuka1, Masaki Magari1, Hiroshi Tokumitsu1 (1. Okayama Univ., 2. Fac. Eng., Okayama Univ.)
[1P-459]Internalization of fission yeast TRP ion channel Pkd2 requires its C-terminal region
○Takayuki Koyano1, Kaori Onishi1 (1. Shigei Medical Research Institute)
[1P-460]Elucidation of the mechanism of tumor progression via abnormal O-GlcNAcylation of nucleoporins
○Satomi Mukai1, Tatsuhiro Sato1, Yasuhiro Kamei2, Kagayaki Kato2, Emi Mishiro-Sato3,4, Masahiro Aoki4, Norikazu Yabuta5, Kenzo Hiroshima6, Yoshitaka Sekido1 (1. Div. of Cancer Biol., Aichi Cancer Ctr. Res. Inst., 2. Trans-Scale Biol. Ctr., National Inst. for Basic Biol., 3. Inst. of Transformative Bio-Molecules, Nagoya Univ., 4. Div. of Pathophysiology, Aichi Cancer Ctr. Res. Inst., 5. Res. Inst. for Microbial Diseases, Osaka Univ., 6. Dept. of Biochem. and Genetics, Chiba Univ. Grad. Sch. of Med.)
[1P-461]The RNA/ubiquitin double-binding protein ALIX regulates the formation of lentiviral particles.
○Kenta Hagiuda1, Yuya Himi1, Keijun Kakihara2, Masayuki Komada1,2, Toshiaki Fukushima1,2 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[1P-462(1MS-02-06)]Elucidation of the stress response mechanism through spatiotemporal regulation of SAPKK
○Hisashi Moriizumi1, Takanori Nakamura 1, Youngmin Cho2, Toru Kawanishi 3, Hiroyuki Takeda3, Takashi Suzuki 4, Mutsuhiro Takekawa 1 (1. IMS, The Univ. of Tokyo, 2. Grad. Sch. Engn. Sci., Osaka Univ., 3. Sch. of Sci., The Univ. of Tokyo, 4. Cent. for Math Model and Data Sci., Osaka Univ)
[1P-463]Branched Chain Amino Acids (BCAA) upregulate the tumor suppressor PDCD4 inhibiting the autophagy system via the activation of mTORC1 in Huh7 hepatoma cells.
○RASHEDA PERVEEN1, Iwata Ozaki1, Hirokazu Takahashi1, Takuya Kuwashiro1, Sachiko Matsuhashi1 (1. Department of Internal Medicine, Faculty of Medicine, Saga University)
[1P-464]Cellular ROS initially promote SMG1/DNAPK-NRF2 axis to prevent ferroptosis
○Yumiko Fujikawa1,2, Hirotatsu Imai3, Kae Suzuki4, Hidehito Kuroyanagi3, Daisuke Utsumi5, Kenzo Takahashi6, Shigeo Ohno2, Akio Yamashita1 (1. Dept. of Invest. Med., The Univ. of the Ryukyus, 2. Res. Inst. for Dis. of Old Age, Juntendo Univ. Sch. of Med., 3. Dept. of Biochem., Univ. of the Ryukyus, 4. Dept. of Biochem. and Mol. Biol., Saitama Univ., 5. Adv. Med. Res. Cent., Univ. of the Ryukyus, 6. Dept. of Derm., Grad. Sch. of Med., Univ. of the Ryukyus)
[1P-465]Investigating the Importance of C-Terminal Sequence Diversity in G-Protein Coupled Receptors: Insight from Mouse μ-Opioid Receptor Isoforms
○Riko Suzuki1, Ryoji Kise1, Asuka Inoue1,2 (1. Grad Sch of Pharm Sci, Tohoku Univ, 2. Grad Sch of Pharm Sci, Kyoto Univ)
[1P-466]Molecular mechanisms of spontaneous senescent cell formations and its effect on surrounding cancer cells via SASP
○Yuya Mihara1, Rina Murai1, Ayano Itai1, Yuki Akamatsu1, Taiki Nagano2, Hayato Tokumoto3, Tetsushi Iwasaki1,2, Shinji Kamada1,2 (1. Dept. of Biol., Grad. Sch. of Sci., Kobe Univ., 2. Biosig. Res. Ctr., Kobe Univ. , 3. Dept. of Biol., Grad Sch. of Sci., Osaka Metropolitan Univ.)
[1P-467]Mechanisms of cold stress response in Saccharomyces cerevisiae
○Suzuna Tabe1, Yuichi Kimura1, Hidehiko Uchiyama1, Koji Masuda1 (1. Tokyo Univ. of Agri.)
[1P-468]A sensitive fluorescent probe for ERK reveals significance of minimal EGF-induced kinase activity on transcription
○WEISHENG ZHANG1, Jun Nakayama2, Yukino Inomata2, Shigeki Higashiyama2, Toru Hiratsuka1,2 (1. Dept. Molecular Oncology, Grad. Sch. of Med. Osaka Univ., 2. Dept. Oncogenesis and Growth Regulation, Osaka Int. Cancer Inst.)
[1P-469]cytoplasmic tail of occludin regulates cell proliferation with or without HIF-1a via its cysteines
○Satoshi Tanaka1,2, Koji Taniguchi2 (1. CCDI Hokkaido Univ. , 2. Dep. Pathol, Hokkaido Univ.)
[1P-470(1PS-04-01)]Cytoplasmic fluidization leads to dormancy breaking in fission yeast spore
○Keiichiro Sakai1, Yohei Kondo2, Yuhei Goto2, Kazuhiro Aoki2 (1. Brooklyn College of The City University of New York, 2. Graduate School of Biostudies, Kyoto University)
[1P-471]Artificial genetic circuit converted by serine recombinase function
○Toshiki Saito1, Koko Nakata2, Shunsuke Takahashi2 (1. Dept. Life Sci. Eng., Grad. Sch. Sci. Eng., Tokyo Denki Univ., 2. Div. Life Sci. Eng., Sch. Sci. Eng., Tokyo Denki Univ.)
[1P-472]G protein-coupled receptor Gprc5a is a novel parathyroid hormone-inducible gene that functions as a repressor of BMP signaling and suppresses the proliferation and differentiation in osteoblasts.
○Chisato Sampei1, Kosuke Kato1, Yasuhiro Arasaki1, Yuta Kimura1, Takuto Konno1, Kanon Otsuka1, Masaki Noda2, Yoichi Ezura3,4, Yukihiro Kohara1, Tadayoshi Hayata1 (1. Dept. of Mol. Pharmacol., Grad. Sch. of Pharm. Sci., Tokyo Univ. of Sci., 2. Ctr. for Stem Cell and Regen. Med., Inst. of Sci. Tokyo, 3. Dept. of Jt. Surgery and Sports Med., Grad. Sch. of Med. and Dent. Sci., Inst. of Sci. Tokyo, 4. Dept. of Occup. Ther., Fac. of Health and Med. Sci., Teikyo Heisei Univ.)
[1P-473]Purification and functional analysis of extracellular vesicles from Aspergillus oryzae
○Mana Yamamoto1, Hiroshi Takemori1 (1. Gifu Univ.)
[1P-474]Inhibition of cell proliferation by theanine uptake into nervous system cell lines.
○Yuuri Matsushima1, Katsuki Tanaka1, Shinnosuke Yamaura2, Koji Komori2, Kou Kawada2, Koithi Kawata1, Kyosuke Uno1, Nobuyuki Kuramoto1,3 (1. Sestunan Univ. Kinoukeitai, 2. Sestunan Univ. Rinsyouyakuri, 3. Yoboyakurigaku Pharm.)
[1P-475]Synthesis of SIK2 inhibitor and elucidation of physiological function by inhibiting SIK2
○Ryusei Takashima1, Hiroshi Takemori2, Kyoji Furuta2 (1. Gifu University,Engineering, 2. Gifu Graduate School, Natural Science)
[1P-476]Functional Differentiation of Receptor Activity-Modifying Proteins RAMP1 and RAMP3: Differences in Inflammatory Responses between Macrophages and Colonic Epithelial Cells
○Takayuki Sakurai1,2, Marina Hayashi2,3, Kamiyoshi Akiko1,2, Tanaka Megumu1,2, Ichikawa-Shindo Yuka2, Yunlu Zhao2, Yorisige Matuda2, Yan Zhang2, Qianqian Guo2, Peixuan Li2, Ken Hoshiyama2, Jiake Li2, Jun Duan2, Takayuki Shindo1,2 (1. Shinshu Univ. Inst.Biomed.Sci., 2. Shinshu Univ. Sch.Med. , 3. Shinshu Univ. Grad.Med.)
[1P-477]Internalization of an orphan GPCR highly expressed in brain induced by novel ligand compounds
○Hijiri Yoshida1, Hiroyuki Hirano2, Hiroyuki Osada2,3, Shigeki Takeda1 (1. Graduate School of Science and Technology, Gunma University, 2. RIKEN center for Sustainable Resource Science, 3. Institute of Microbial Chemistry (BIKAKEN))
[1P-478]Therapeutic efficacy analysis of dihydropyrazine in multiple organs failure by sepsis
○Madoka Sawai1, Yutaka Tatano1, Hidetoshi Tozaki-Saitoh1, Katsuya Miyake3, Shunji Itoh4, Taku Kaitsuka1, Hisao Kansui2, Miyauchi Yuu2, Shinji Takechi2 (1. Sch. Pharm., at Fukuoka. Int. Univ. Health & Welfare., 2. Fac. Pharmaceut. Sci., Sojo Univ., 3. Cbmr., at Narita. Int. Univ. Health & Welfare., 4. Dept. Health Sci., Grad. Sch. Health Sci., Kansai Univ. Health Sci.)
[1P-479]Parathyroid hormone promotes spontaneous Ca2+ fluctuations in growth plate chondrocytes
○Xinnan Meng1, Atsuhiko Ichimura1,2, Hiroki Nagatomo1, Hiroshi Takeshima1 (1. Kyoto University , 2. Ritsumekan University)
[1P-480]Scg2 promotes axon rewiring of the corticospinal tract after stroke
○Tokiharu Sato1, Yuka Nakamura1, Kohei Ikarashi1, Masato Yano2, Masaki Ueno1 (1. Department of System Pathology for Neurological Disorders, Brain Research Institute, Niigata University, 2. Division of Neurobiology and Anatomy, Graduate School of Medicine and Dental Sciences, Niigata University)
[1P-481]Regulation of myokine expression by nutrient and heat interactions in mouse skeletal muscle
○Nozomi Yazawa1, Yuka Kudo1, Yuho Mizuseki1, Keigo Murata1, Taku Nedachi1 (1. Graduate School of Life Sciences, Toyo University)
[1P-482]Biased GLP-1R agonism by polymethoxyflavones
○Kazunori Hashimoto1, Chihiro Ito1, Satsuki Miyazaki2, Jun-ichi Miyazaki2, Motoyuki Shimizu1, Masashi Kato1, Murata Tomiyasu1 (1. Meijo Univ. , 2. Osaka Univ.)
[1P-483]Stress responsive signals regulating the expression of GDF15 under hypoxic conditions
Aiko Mizuno1, Shusuke Tanicuhi1, ○Koh Nakayama1 (1. Asahikawa Medical University)
[1P-484]Identification of CaMKIγ phosphorylation substrates using in vivo BioID-based proximal protein labeling
○Ryusuke Shiota1,2, Pin-Wu Liu1,3, Shuhei Ueda1,2, Kouhei Nishino4, Honoka Tanaka1,2, Shin-ichiro Horigane1,2, Daisuke Mori5, Hidetaka Kosako4, Sayaka Takemoto1,2 (1. Department of Neuroscience, Research Institute of Environmental Medicine, Nagoya University, , 2. Department of Molecular/Cellular Neuroscience, Nagoya University Graduate School of Medicine, , 3. Laboratory of Systems Neuropharmacology, Graduate School of Medicine, Kyoto University,, 4. Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, , 5. Brain and Mind Research Center, Nagoya University,)
[1P-485]Nuclear translocation of FOXO3a by violaceoid F through the inhibition of CRM1 suppresses HeLa cell growth
○Nobumoto Watanabe1, Emiko Sanada1, Akiko Okano1, Toshihiko Nogawa1, Yui Mazaki1, Muroi Muroi1, Yoko Yashiroda1, Minoru Yoshida1,2, Hiroyuki Osada1,3 (1. RIKEN CSRS, 2. Univ. Tokyo, 3. BIKAKEN)
[1P-486]Competitive cellular interaction via autophagy during tissue development
○Shogo Harada1, Eiji Inoue1, Kohki Kawane1 (1. Life sci., Kyoto Sangyo University)
[1P-487]Analysis of the dynamics of adhesion between cells and extracellular matrix during cell extrusion
○Rukiya Shimoyama1, Ruka Kamikawa1, Kohki Kawane1 (1. Life sci.,Kyoto Sangyo University)
[1P-488]Analysis of the mechanisms by which cells sense density to induce cell death and arrest proliferation
○Eiji Inoue1, Kodai Murayama1, Harada Shogo1, Koki Kawane1 (1. Life sci. , Kyoto Sangyo University)
[1P-489]Analysis of the execution mechanism of cell extrusion during tissue development using Drosophila epithelial tissue
○Marina Awai1, Haruna Kajita1, Atsuto Nakagawa1, Akihito Kira1, Kohki Kawane1 (1. Life sci., Kyoto Sangyo University)
[1P-490]Involvement of macrophages in cell extrusion
○Atsuto Nakagawa1, Kohki Kawane1 (1. Life sci., Kyoto Sangyo University)
[1P-491]Role of caspases in cell turnover in the Drosophila intestinal epithelium
○Yoshiki Miyaura1, Akihito Kira1, Seisuke Kimura1, Koki Kawane1 (1. Life sci., Kyoto Sangyo Univ.)
[1P-492]Lipid dynamics during ferroptosis observed in situ using Raman imaging
○Ryota Dobashi1, Masato Machida2, Shinji Kajimoto1,2, Takakazu Nakabayashi1,2 (1. Faculty of Pharmaceutical Sciences, Tohoku University, 2. Graduate School of Pharmaceutical Sciences, Tohoku University)
[1P-493]Novel cytoplasmic mRNA granules regulate cell-fate decision under mitochondrial stress
○Taiki Baba1, Susumu Tanimura1, Kohsuke Takeda1 (1. Cell Regulation, Grad. Sch. Biomed. Sci., Nagasaki Univ.)
[1P-494]Plasma membrane-localized activation of caspases via electrostatic interactions
○Yusuke Taira1, Yugo Miyata2, Katsumori Segawa2, Masayuki Miura1, Natsuki Shinoda1 (1. The University of Tokyo, 2. Medical Research Institute Tokyo Medical and Dental University)
[1P-495]Elucidation of Cullin-mediated Apoptosis Induction Signaling Pathway by RID-B
○Ayaka Kaneda1, Kyoka Komukai2, Eri Murata2, Fumi Satoh2, Takatsugu Murata2, Isamu Shiina2, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Tokyo Denki Univ, 2. Tokyo Univ. of Sci)
[1P-496]Association between suppression of autophagy and enhancement of necroptosis in diabetic kidney after ischemia-reperfusion.
○Reo Takahashi1, Yukika saga1, Ryusuke Hosoda1, Yuki Tatekoshi1, Atsushi Kuno1 (1. Department of Pharmacology, Sapporo Medical University School of Medicine)
[1P-497]Development of a novel lifespan evaluation method using budding yeast
○Kyosuke Hagiri1, Yoshika Hosono2, Masahiko Harata1, Chihiro Horigome1 (1. Tohoku University Graduate School of Agricultural Science, 2. Tohoku University Faculty of Agriculture)
[1P-498]Identification of reactive oxygen species that induce spoptosis, a novel and distinctive mode of regulated cell death
○Ko Eto1 (1. Kumamoto Univ.)
[1P-499]Effects of boysenberry extract on the heat response of mouse skin cells
○Lanyi Liu1, Tasuku Nakajima1, Takeshi Miura1, Taku Nedachi1 (1. Toyo University Graduate School)
[1P-500]Do motor neurons die of spoptosis, a novel cell death mechanism, in amyotrophic lateral sclerosis?
○Taichi Kurogi1, Ko Eto1 (1. Dept. Biol. Sci., Grad. Sch. Sci. & Tech., Kumamoto Univ.)
[1P-501]Establishment of a screening system to elucidate the mechanisms that determine live or dead under the UPR
○Kenshin Kashiwagi1, Yukako Tokutake1, Shinichi Yonekura1 (1. Shinshu University)
[1P-502]Reduction of intracellular Mg2+ leads to cell death via activating NF-κB pathway
○Koyuki Kawamura1, Yosuke Funato1, Hiroaki Miki1 (1. Kyoto University)
[1P-503]Construction of maximal overexpression systems and emergence of new phenotypes.
○Shotaro Namba1, Hisao Moriya1 (1. Okayama University)
[1P-504]Enhancement of optogenetic tool for gene expression in mammalian cells
○Shinji C. Nagasaki1, Tomonori D. Fukuda2, Ikumi Nagano2, Saki Inai2, Mayumi Yamada1, Itaru Imayoshi1,2 (1. Institute for Life and Medical Sciences, Kyoto University, 2. Graduate School of BIOSTUDIES, Kyoto University)
[1P-505]The impact of detachment enzyme treatment time on substrate adhesion in the passaging culture of iPS cells
○Koki Abe1, Keita Ueno2, Shogo Miyata2 (1. Shimizu Corporation, 2. Faculty of Science and Technology, Keio university)
[1P-506]Exploring the long-term dynamics of a cell presenting a nonhomogeneous surface tension distribution using a non-conserved continuous membrane model
○Valentina Tyukosova1, Satoru Okuda2 (1. Kanazawa University, Division of Nano Life Science, 2. Kanazawa University, Nano Life Science Institute)
[1P-507]In vivo analysis of mechanoresponse in osteocyte using two-photon microscopy
○Akinori Hatano1, Kazumasa Nishino1, Hina Takegami1, Fukunaga Takanobu2, Masamichi Yamamoto3, Keizo Nishikawa1 (1. Dept. of Med. Life Sys., Grad. Sch. of Biomed., Univ. of Doshisha, 2. Fac. of Eng., Univ. of Kyushu, 3. NCVC)
[1P-508]Study of gene functions involved in dimorphism in a basidiomycetous yeast Trichosporon asahii
○Keita Aoki1, Minenosuke Matsutani2, Moriya Ohkuma3, Takashi Sugita4, Yuuki Kobayashi1, Naoto Tanaka5, Masako Takashima1 (1. Yeast syst., Res. Inst., Tokyo Univ. of Agric., 2. NODAI Genome Res. Cent., Tokyo Univ. of Agric., 3. JCM, BRC, RIKEN, 4. Microbiol., Meiji Pharm. Univ., 5. Mol. Microbiol., Biostud., Tokyo Univ. of Agric.)
[1P-509]Evaluation of the novel anticancer screening method based on in silico prediction for flavonoids
○Osei Horikoshi1, Koyo Fujisaki2, Kengo Morohashi2, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Dept. of Sci. Eng., Tokyo Denki Univ., 2. Dept. of Sci. Eng., Chitose Inst. Sci. Tech.)
[1P-510]Investigation of long-term cryopreservation of cultured human corneal endothelial cells for developing cellular products
○Sora Tanaka1, Naoki Okumura1, Yuna Miyawaki1, Yu Shima1, Chieri Izumi1, Makiko Nakahara2, Yasushi Matsuoka2, Noriko Koizumi1 (1. Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, 2. ActualEyes Inc.)
[1P-511]Development of culture substrates and evaluation of compound effects on cultured cells and organoids for the construction of a microphysiological system
○Hiroki Hamaguchi1, Tomoko G. Oyama1, Atsushi Kimura1, Yasuhiro Ohshima1, Kotaro Oyama1, Yusuke Kimura1, Noriko Ishioka1, Mitsumasa Taguchi1 (1. National Institutes for Quantum Science and Technology (QST))
[1P-512]One-cell measurement of Escherichia coli repellent response to multiple repellent stimuli and receptor demethylase CheB kinetics.
○Yugo Tomoda1, Yumiko Uchida1, Akihiko Ishijima1, Hajime Fukuoka1, Youichi Kuroki1 (1. Graduate School of Frontier Biosciences Osaka University)
[1P-513]The control of cell proliferation and differentiation of myoblasts with co-culture secretions of growth factor-producing cells
○Rio Sakaki1, Tsukasa Hara2, Toru Asahi1, Tatsuya Shimizu2 (1. School of Advanced Science and Engineering, Waseda Univ., 2. Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical Univ.)
[1P-514]Measuring Ca2+ concentrations in the cytoplasm, mitochondria, endoplasmic reticulum, and extracellular space with multi-color fluorescence lifetime biosensors
○Cong Quang VU1, Loan Thi Ngoc NGUYEN2, Takeru YAMAZAKI1, Satoshi ARAI1,2 (1. Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, 2. Division of Nano Life Science, Kanazawa University)
[1P-515]Inhibition of Wrinkle Formation and Mechanistic Analysis by β-Carboline Alkaloid Compounds
○Rino Nakamura1, Takayuki Yonezawa2, Je-Tae Woo1 (1. Grad. Sch. of Biosci and Biotech., Chubu Univ., 2. Res. Inst. for Biol. Func., Chubu Univ.)
[1P-516]Raman spectroscopic analyses for senescence mechanism of oocyte in mice
○Shotaro Kozaka1, Seiichi Koike1, Yusuke Oshima1 (1. University of Toyama)
[1P-517]Generation of the platform for FLIM biosensors enabling quantitative imaging of steady states at cellular level
○Satoshi Arai1, Cong Quang Vu1, Takeru Yamazaki1 (1. NanoLSI, Kanazawa Univ.)
[1P-518]Maintaining undifferentiated stem cells in a hypoxic culture environment
○Jingshu Piao1, Takanori Sakai1, Takahiro Ogata1, Yoshitaka Ohashi1 (1. Astec CO.,Ltd.)
[1P-519]Involvement of SFK in insulin secretion from pancreatic beta cells
○Ryosuke Yamamoto1, Taiyo Yoshibe1, Kato Yuta1, Eri Mukai1 (1. Ritsumeikan Univ.)
[1P-520]Intracellular delivery of microparticles by electrofusion aiming at semi-artificial secretory cells
Soto Iida1, Ruriko Suzuki1, Masahiko Tanaka1, ○Naohide Hirashima1 (1. Dept. Cell. Biophys., Grad. Sch. Pharmaceut. Sci, Nagoya City Univ.)
[1P-521]The decline in cellular iron content is a crucial element for the execution of the differentiation program in cultured keratinocytes.
○Junya Abe1, Yohei Hirai1 (1. Kwansei Gakuin University)
[1P-522]Development of Co–Culture System for Butanol Production from Pretreated Rice Straw in a Modified VMFB Bioreactor
○Yu-Kuo Liu1, Po-Tai Hu1 (1. Chang Gung University)
[1P-523]Designing an Experimental Protocol Description Language based on Object-Flow Programming
○Kazunari Kaizu1,2, Koichi Takahashi1 (1. RIKEN BDR, 2. NINS ExCELLS)
[1P-524]Isolation and utilization of oleaginous yeast Lipomyces starkeyi mutants: Effects on the growth of Japanese eel
○Yuko Takayama1,2, Takae Hirasawa1,2, Junki Saito1, Wataru Fukusima1, Emi Kuriyagawa1, Michiko Suma3, Shigeaki Saitoh3 (1. Teikyo University, 2. Institute of Lif Sci. Teikyo University, 3. Kurume University)
[1P-525]Elucidation of the regulatory mechanism of follicle development by SPARC (secreted protein acidic and rich in cysteine)
○Saki Tsuji1 (1. Graduate school of Science, Tokyo University of Science)
[1P-526]Recombinase mediated DNA integration in the anhydrobiotic Pv11 cells
○Masahiko Hotta1,2, Yuki Yoshida2, Takahiro Kikawada1,2 (1. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo., 2. Biological Function Research Group, Division of Biomaterial Sciences, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization.)
[1P-527]Application of Near Infrared photoimmunotherapy to cell selection and islet isolation.
○Koya Shinohara1, Masayuki Shimoda1 (1. Reserch Institute National Center for Global Health and Medicine)
[1P-528]Analysis of heat stress resistance exhibited by newt fibroblasts
○Ran He1,2, Tomokazu Yamane1,2, Mai Takehara1,2, Toshinori Hayashi1,2, Kazuko Okamoto1,2 (1. Hiroshima University Amphibian Research Center, 2. Graduate School of Integrated Sciences Life, Hiroshima University)