Session Details
[2P-2]Poster Presentation
Thu. Nov 28, 2024 12:55 PM - 2:55 PM JST
Thu. Nov 28, 2024 3:55 AM - 5:55 AM UTC
Thu. Nov 28, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 2 (Marine Messe Fukuoka Hall B, 1F)
3. Development and Regeneration
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases - a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- o. Others
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases - a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- o. Others
[2P-529(2AS-05-02)]Identification of a novel regenerative regulator by trajectory-based cell lineage analysis in Xenopus tadpole tail regeneration
○Sumika Kato1, Takeo Kubo1, Taro Fukazawa1 (1. Dept. Biol. Sci., Grad. Sch. Sci., Univ. Tokyo)
[2P-530]Elucidation of the mechanism by which birds acquired flight feathers evolutionarily.
○Momoko Kyushin1, Keiji Kinoshita2, Takayuki Suzuki1 (1. Osaka Metropolitan Univ., 2. Yunnan Agricultural Univ.)
[2P-531]Fgf3 and Fgf8a mediates coordinated lens and retinal development in zebrafish
○Yuki Takeuchi1, Ichiro Masai1 (1. OIST)
[2P-532]Unraveling the genetic regulatory network controlling L-R asymmetry formation in the anterior gut of Drosophila melanogaster
○Florian Lucas Neugebauer1, Takamasa Higashi1, Daiki Umetsu1, Mikiko Inaki2, Akira Nakamura3, Kenji Matsuno1 (1. Osaka University, 2. Hyogo University, 3. Kumamoto University)
[2P-533]Generation and analysis of conditional-rescue transgenic mice for c-Kit, Sl, and Inv genes.
Eiki Sakurai1, Takaaki Fushimi1, ○Daisuke Watanabe1 (1. kitasato Univ.)
[2P-534]Development of the cloacal cilia in the Xenopus larva
○Mika Kin1, Masato Owada2, Kazue Mogi3, Ryuji Toyoizumi1,3 (1. Division of Biological Sciences, Graduate School of Science, Kanagawa University, 2. Department of Biological Sciences, Faculty of Science, Kanagawa University, 3. Institute for Integrated Science, Kanagawa University)
[2P-535(2PS-08-02)]Blood feeding-induced mechanical tension drives gut homeostasis in mosquitoes
○Emi Maekawa1,2, Hiroka Aonuma1,2, Hirotaka Kanuka1,2 (1. Department of Tropical Medicine, The Jikei University School of Medicine, 2. Center for Medical Entomology, The Jikei University School of Medicine)
[2P-536]Understanding the mechanism of brown body color formation in goldfish
○Yurina Satou1, Rui Tang1, Soichiro Fushiki1, Saori Matsumoto1, Shingo Yoshimi2, Atsushi Nagano3, Hideki Noguchi4, Atsushi Toyoda5, Yoshihiro Omori6,1 (1. Grad. Sch. of Bioscience, Nagahama Inst. of Bioscience and Technology, 2. Yatomi Station, Aichi Fisheries Res. Inst., 3. Dept. of Agriculture, Ryukoku Univ., 4. Joint Support-Center for Data Science Research (ROIS-DS), 5. Advanced Genomics Center, National Inst. of Genetics, 6. Grad. Sch. of Integrated Sciences for Life, Hiroshima University)
[2P-537]Roles of let-2 and emb-9, genetic suppressors of the C. elegans mig-17 mutant, in aging and lifespan
○Moeka Yoshida1, Yukimasa Shibata1, Kiyoji Nishiwaki1 (1. Kwansei Gakuin Univ.)
[2P-539]A study of the gill morphology of zebrafish with a deficiency in OGR1
○Kurumi Fujiwara1, Hideaki Tomura2 (1. Meiji University, Graduate School of Agriculture, Department of Life Sciences, 2. Meiji University, Institute of Endocrinology)
[2P-540]Elucidation of the mechanism of periocular edema formation in goldfish.
○Taichi Takahashi1, Shingo Yoshimi2, Atsushi Nagano3, Hideki Noguchi4, Atsushi Toyoda5, Yoshihiro Omori1,6 (1. Grad.Sch.of Bioscience, Nagahama Inst. of Bioscience and Technology , 2. Yatomi Station, Aichi Fisheries Res. Inst., 3. Dept. of Agriculture, Ryukoku Univ. , 4. Joint Support-Center for Data Science Research (ROIS-DS), 5. Advanced Genomics Center, National Inst. of Genetics, 6. "Grad. Sch. of Integrated Sciences for Life, Hiroshima University, ")
[2P-541]Phenotypic analysis of the pharyngeal arch, thymus and heart in mice with mutations in the evolutionarily conserved amino acid sequences WRPW and FPVQ of Ripply3
○Tadashi Okubo1, Daisuke Narita1, Ryusuke Ishizuka1, Yosuke Kajiyama1, Yudai Yabe1, Shinji Takada2 (1. Department of Lab Animal Sci. Kitasato Univ. School of Medicine. , 2. NIBB, NINS)
[2P-542]The role of the C. elegans fbl-1/fibulin-1 gene in aging and life span regulation
○Yijing Huang1 (1. kwansei university)
[2P-543]Niche-Specific Regulation of MET Events within Kidney Organoidsche-Specific Regulation of MET Events within Kidney Organoids
○Rio Noto1, Minoru Takasato1,2 (1. RIKEN, 2. Kyoto Univ.)
[2P-544]Developmental analysis of tracheal cartilage using ES cell differentiation induction and live imaging
○Takumi Matsuura1 (1. RIKEN BDR)
[2P-545]Role of CXCR4/SDF1 signaling in the initial migration of cardiac neural crest cells
○Yumi Unozu1, Kunio Inoue1, Saori Tani-Matsuhana1 (1. Department of Biology, Graduate School of Science, Kobe University)
[2P-546]Functional analysis of RAMP in muscle regeneration
○Eriko Ogushi1, Yuki Nakayama2 (1. Kumamoto Univ. Grad. Sch. of Sci. and Tech. , 2. Kumamoto Univ. Fac. of Adv. Sci. Tech.)
[2P-547]Characterization and functional investigation of a SOX transcription factor which suppresses hypertrophy of the insect endocrine organ in fruit fly Drosophila melanogaster
○Yosuke Mizuno1, Ryusuke Niwa2 (1. Grad. Sch. Sci. Tech., Univ. Tsukuba, 2. TARA, Univ. Tsukuba)
[2P-548]Analyzing the Function of Needle-Like Collagen Structures, Actinotrichia, in Fish Fin Ray Bone Formation
○Hiromu Hino1, Junpei Kuroda1, Shigeru Kondo1 (1. Osaka university, Frontier of Bio Sciences)
[2P-549]Mechanism of Left-Right polarity formation in the Drosophila brain by ecdysone signaling
○Komomo Suyama1, So Sakamura1,2, Kenji Matsuno1 (1. Osaka Univ., 2. University of Hyogo)
[2P-550]Mechanism of how the shapes emerge from epithelial monolayer
○Minami Aoyama1, Komaki Ninomiya1, Erina Kuranaga1,2 (1. Tohoku Univ., 2. Kyoto Univ.)
[2P-551]Cdh2 as a Hes7 downstream target regulates presomitic mesodermal cell differentiation by supporting FGF signaling
○Xueqi JIA1, Akihiro Isomura1, Ryoichiro Kageyama1 (1. RIKEN, CBS)
[2P-552]Histological analysis of Drosophila macrophages retaining fragmented larval muscle tissue for a prolonged time during the remodeling of muscles
○Saki Hirao1, Kenji Matsuno1, Daiki Umetsu1 (1. Osaka University)
[2P-553]The role of macrophages in regeneration in Pleurodeles waltl
○Yudai Matsumoto1, Haruka Suzuki1, Akimasa Fukui1 (1. Chuo University)
[2P-554]How Drosophila cuticular proteins self-organizize into layers to regulate the whole body shape.
○Haruka Nagao1, Sota Sakizaki1, Reiko Tajiri2 (1. Dep. of Biology, Fac. of Sci., Chiba Univ., 2. Dep. of Biology, Grad. Sch. of Sci., Chiba Univ.)
[2P-555]Function of type IX collagen essential for the orientation of collagen structures distributed at the tip of zebrafish fin
○Jin Hagiwara1, Hibiki Nakagawa2, Toshihiro Aramaki1, Shigeru Kondo1, Junpei Kuroda1 (1. FBS, Univ. of Osaka, 2. Grad. Sch. of Arts and Sciences, Univ of Tokyo)
[2P-556]Regulatory mechanism for 3D architecture formation by chitin microfibrils in the cuticle of Drosophila
○Sogo Kataoka1, Reiko Tajiri2 (1. Department of Biology, Faculty of Science, Chiba Univ., 2. Graduate School of Science, Chiba Univ.)
[2P-558]The role of FGF signaling in the blastogenesis of Botryllus primigenus
○Takumi Sasada1, Takeshi Sunanaga1 (1. Dept. of Sci. Tec., Integr. Art. Sci.,, Kochi univ.)
[2P-559]Positive transcription elongation factor b (P-TEFb) maintains epithelial homeostasis in Drosophila intestine
○Miku Kusakabe1, Shoichiro Kurata1, Tamaki Yano1 (1. Pharmaceutical Sciences, Tohoku University)
[2P-560]Observation of formation process of muscle-tendon junctions using Light sheet microscopy
○Ramu Sagasaki1, Masafumi Inui1 (1. Laboratory of Animal Regeneration systemology, Department of Life Sciences, School of Agriculture, Meiji University)
[2P-561]Functional analysis of asynchronous Hes1 oscillations in the neural tube formation
○Yuki Maeda1, Ryoichiro Kageyama1 (1. RIKEN Center for Brain Science)
[2P-562]Production of cardiomyocytes using synthetic Notch
○Hiyori Suzuki1, Masato Nakahara1, Chi Chin KAO1, Tomoe Ueyama2,3, Masato Hatsusegawa1, Yukihiro Harada1,3, Shu Nakao3,4, Teruhisa Kawamura1,3 (1. College of Life Science, Ritsumeikan University, 2. Research Organization of Science and Technology, Ritsumeikan University, 3. Ritsumeikan Global Innovation Research Organization, 4. Department of Physiology, Tokai University School of Medicine)
[2P-563]Mechanism that links muscle contraction to cuticle deformation during pupariation in Drosophila.
○Yufuko Ando1, Reiko Tajiri2 (1. Dept. of Biology, Fac. of Sci.,Chiba Univ., 2. Grand. Sch of Sci., Chiba Univ)
[2P-564]Distribution of type I and type II collagen in the intercalary element (IE), the digital skeletal element specific to tree frogs, and the evolutionary origin of the IE
○Kensuke Nakanishi1,2, Keisuke Nakajima1,2, Nobuaki Furuno1,2, Ichiro Tazawa1,2 (1. Hiroshima Univ., 2. Hiroshima Univ. Amphibian Research Center)
[2P-565]Microenvironment and Cell Cycle Stress-Driven Transition of ESC to a 2-Cell Embryo-Like State
○Hideo Suzuki1, Makoto Kashima2, Shinpei Yamaguchi1 (1. Toho Univ. Sci. Bio., 2. Toho Univ. Sci. Biomol.)
[2P-566]Analysis of genomic imprinting in a novel serum-free medium
○Kazunori Takeda1, Yuto Hiruma2, Akito Uematsu1, Yohei Iizaka3, Shinpei Yamaguchi1,2 (1. Toho University Graduate School of Science , 2. Toho University, Faculty of Science, Department of Biology, 3. Toho University Faculty of Pharmacy)
[2P-567(2AS-16-05)]Insights into Genomic Imprinting from the Mice with Parthenogenetic Embryo-derived Brain
○Shinpei Yamaguchi1, Marina Takechi1,2 (1. Toho University, 2. Osaka University)
[2P-568]Derivation of Mouse Androgenetic Embryo with Normalized X-Chromosome Inactivation
○Masataka Tsuchiya1, Makoto Kashima2, Shinpei Yamaguchi1 (1. Toho University, sci, bio, 2. Toho Univ, sci, biomol,)
[2P-569(2MS-06-05)]Nutrient fluctuations promote recovery of intestinal stem cell pool in Drosophila
○Tenki Nakasugi1, Hiroki Nagai2, Masayuki Miura1, Yuichiro Nakajima1 (1. The University of Tokyo, 2. Institute of Science and Technology Austria (ISTA))
[2P-570]Development of a Rat Model for Hematopoietic Stem Cell Transplantation Without Irradiation
○Ryuya Iida1, Saeko Ishida1, Jinxi Wang1, Kosuke Hattori1, Kazuto Yoshimi1,2, Satoshi Yamazaki3,4, Tomoji Mashimo1,2 (1. Division of Animal Genetics, Laboratory Animal Research Center, IMSUT, The University of Tokyo, 2. Division of Genome Engineering, Center for Experimental Medicine and Systems Biology, IMSUT, University of Tokyo, 3. Division of Cell Regulation, Center of Experimental Medicine and Systems Biology, IMSUT, The University of Tokyo, 4. Laboratory of Stem Cell Therapy, Faculty of Medicine, University of Tsukuba)
[2P-571]Patient-derived iPSC brain organoids as a model for cognitive phenotypes of Duchenne Muscular Dystrophy
○Chaitra Sathyaprakash1, China Tatebori1, Katsuhiko Kunitake1, Reiko Terada1, Tatsuo Mano2, Tadafumi Hashimoto2, Daisuke Kawauchi3, Momoko Watanabe4, Mariko Taniguchi-Ikeda5, Hideya Sakaguchi6, Yoshitsugu Aoki1 (1. Department of Molecular Therapy, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 2. Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, 3. Department of Neuro-Oncology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, 4. Department of Anatomy & Neurobiology, Sue & Bill Gross Stem Cell Research Center, School of Medicine, University of California, Irvine, Irvine, CA, USA, 5. Department of Clinical Genetics, Fujita Health University Hospital, Toyoake, Aichi, Japan, 6. BDR-Otsuka Pharmaceutical Collaboration Center, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan)
[2P-572]Two waves of stomach cell production occur from fetal multipotent progenitor cells and adult stem cells in development and tissue regeneration in mice.
○Motomi Osato1,2,3, Kazuto Suda2,4, Tomomitsu Doi5, Akiko Niibori-Nambu2, Akihiro Yamamura6, Tomomasa Yokomizo7, Atsuyuki Yamataka4, Motoyoshi Endo5 (1. Kumamoto Univ, 2. Natl Univ Singapore, 3. Kumamoto Kenhoku Hosp, 4. Juntendo Univ, 5. Univ Occup Environment Health, 6. Tohoku Univ, 7. Tokyo Women's Med Univ)
[2P-573]The Importance of Organoid Techniques in Gut Microbes Studies
○Nobuo Sasaki1 (1. Gunma University)
[2P-574(2AS-05-03)]The roles of the extracellular matrix, fibulin-5, in the regulation of epidermal stem cells during skin aging
○Wenxin Fan1,2, Mizuho Ishikawa1,2, Erna Raja1,3, Ahmed M Hegazy1,5, Yen Xuan Ngo1,4, Hiromi Yanagisawa3,4, Aiko Sada2,1,3 (1. IRCMS, Kumamoto Univ., 2. MIB, Kyushu Univ., 3. TARA, Univ. of Tsukuba., 4. Faculty of Medicine, Univ. of Tsukuba., 5. Zoology Dept., Minia Univ.)
[2P-575]Utilizing organoid culture technology to produce cultured meat for cats.
○Yuko Nagashima1, Yuki Kobayashi1, Yoshiko Naito1, Haru Yamamoto1, Tatsuya Usui1, Kazuaki S1 (1. Tokyo University of Agriculture and Technology)
[2P-576]Characterization of quail embryonic stem cells (qESCs) established with Wnt inhibition
○Mei Matsuzaki1, Ryota Kajihara1, Tenkai Watanabe1, Takumi Terada1, Ryo Ezaki1, Hiroyuki Horiuchi1,2 (1. Hiroshima Univ., 2. Genome Edit. Innov. Ctr.)
[2P-577]Identification and analyses of Nr0b1 through CRISPR screen for endogenous OCT4 protein levels
○Masaki Matsumura1, Miyagami Syunichi2, Ishiuchi Takashi1 (1. Fac. of Life and Environ. Sci., Univ. of Yamanashi, 2. Fac. of Life and Environ. Sci., Univ of Yamanashi)
[2P-578]The effects of the anticancer drug STAT3 inhibitor on the proliferative capacity of mouse ES cells
○Takeshi Matsuo1, Yuta Aoki1, Sae Kuroki2, Aoi Kuroki1, Yumi Horiuti2, Atushi Ueda3, Tadayuki Aoki1,2 (1. Fukuoka University of Technology, 2. Fukuoka Institute of Technology, 3. Tokai University Faculty of Medicine)
[2P-579]Development of Regenerative Therapy for Pediatric Tracheal Disorders using Human iPSC-Derived Cartilage Tissue
○Kokoro Furutani1, Shojiro Hanaki1, Yuki Fujisawa1, Tomoka Takao1, Daisuke Yamada1, Ryosuke Iwai2, Takeshi Takarada1 (1. Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2. Institute of Frontier Science and Technology, Okayama University of Science)
[2P-580]Apoptosis induced during re-culture after hypothermic storage of mammalian cells is due to ferroptotic stress and ER stress during cold storage
○Akira Aizawa1, Masakazu Hayashi1, Yuki Gen1, Naojiro Minami2, Shuntaro Ikeda2, Kazuaki Matsumura3, Shokyu Gen1 (1. BMG Inc., 2. Graduate School of Agriculture, Kyoto Univ., 3. School of Materials Science, JAIST)
[2P-581]Mechano-activation of longevity promoting factors in the aged mesenchymal stem cells via substrate stiffness.
○Thasaneeya Kuboki1, Satoru Kidoaki1 (1. Kyushu University)
[2P-582(2AS-17-07)]A human p53 isoform, Δ133p53α, regulates cellular senescence and stem cell abilities of human bone marrow-derived mesenchymal stem/stromal cells via full-length p53
○Kaori Fujita1, Nanako Tamagawa2, Gaiki Ryo1, Bořivoj Vojtěšek3, Curtis C Harris4, Noriyuki Tsumaki5 (1. Graduate school of Engineering Science, Akita University, 2. Faculty of Engineering Science, Akita University, 3. Masaryk Memorial Cancer Institute, 4. Center for Cancer Research, NCI, NIH, 5. Graduate School of Medicine / Frontier Biosciences / WPI-PRIMe, The University of Osaka)
[2P-583]Molecular mechanism to activate the cell growth of hair follicle stem cells with the addition of stem cell conditioned media
○Eugene Hayato Morita1, Shuhei Mori1, Yuki Tanaka2, Maki Sato2, Yukio Mitsui2 (1. Josai University, 2. Horus Co., Ltd.)
[2P-584]The role of RNF32 ubiquitin ligase in intestinal stem cell.
○Motoharu Sarubo1, Yasuhiro Mouri1, Daniele Guardavaccaro2, Yasusei Kudo1 (1. Department of Oral Bioscience Tokushima University Graduated school of Biomedical science, 2. Department of Biotechnology, University of Verona, Italy.)
[2P-585]Generation of iPS cells from rodent Müller glia
○Tomoe Ueyama1, Fujimoto Mina2, Kao Chih Chi2, Yukihiro Harada2, Teruhisa Kawamura2,3 (1. Res. Org. of Sci. and Tech., Ritsumeikan Univ., 2. Dept. of Biomed. Sci., Grad. Sch. of Life Sci., Ritsumeikan Univ., 3. Global Innov. Res. Org., Ritsumeikan Univ.)
[2P-586]Analysis of Extracellular Secretory Proteins in Mesenchymal Stem Cells by Proteomics
○Yuzuka Kuba1, Haruka Sugiyama1, Manato Oishi1, Sotarou Mizuno1, Tohru Sugawara2, Nana Kawasaki2 (1. Yokohama City University, 2. Graduate School of Medical Life Science, Yokohama City University)
[2P-587]The Role of the R-Ras Binding Domain of PIEZO1 in Promotion of Osteoblast Differentiation from BMSCs
○Asuna Sugimoto1, Muhammad Dhiaulfikri Nauval Hadiana1, Kokoro Iwata1, Rika Kurogoushi1, Yumiko Nakashima1, Manami Tanaka1, Tsutomu Iwamoto1 (1. Department of Pediatric Dentistry / Special Needs Dentistry, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University)
[2P-588]Single nucleus RNA-seq analysis of skeletal muscle cell lineage in mouse embryo
○Yutaro Kawa1, Yuki Yamaki1, Yuta Tuchiya1, Keitaro Wada1, Ramu Sagasaki1, Masafumi Inui1 (1. Meiji Univ.)
[2P-589]Analysis of factors associated with improved liver function using iPS-small intestine cell co-culture systems.
○Yuna Osada1, Shoen Kume1, Nobuaki Shiraki1, Takumi Saito2, Teruhiko Watanabe2, Ritoru Kimura1 (1. Science Tokyo, 2. Kanto Chemical Co., Inc.)
[2P-590]Functional analysis of epidermal fatty acid-binding protein (FABP5) in keratinocytes differentiation
○Mirei Yuasa1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology, Undergraduate Program of Applied Biology)
[2P-591]The generation of intestinal tuft cells in mouse intestinal crypts by recombinant IL-25 treatment
○Haruo Nakano1, Kota Nakamura1, Yuta Ichino1, Kana Murayama1, Sumire Kikuchi1, Mariko Umemura1, Shigeru Takahashi1, Yuji Takahashi1, Yasuhiro Shinkai1 (1. Tokyo Univ. Pharm. & Life Sci.)
[2P-592]Effect of vitamin C on the differentiation of epidermal keratinocytes
○Yui Hiwatashi1,2, Nana Egawa1,2, Kondo Yoshitaka1, Akihito Ishigami1,2 (1. Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology., 2. Department of Biological Sciences, Tokyo Metropolitan University.)
[2P-593]Reinforcement Learning and Monte-Carlo Tree Search in Cellular Regulation of Gene Expression
○Tomoyuki Yamaguchi1 (1. Research Institute, Nozaki Tokushukai Hospital)
[2P-594]Effects of microgravity on a co-culture system of mesenchymal stem cells and vascular endothelial cells for bone regeneration
○Shunta Kawabata1, Michiyo Honda1 (1. Graduate School of Science and Technology, Meiji University)
[2P-595]Differentiated Cell Discrimination Using AI
○Asuka Suito1, Satoshi Sasaki1 (1. Graduate School Tokyo Univ. of Technology)
[2P-596]Establishment of an Intracellular Ca2+ Elevation Induction System Using Optogenetic Techniques in Primary Cultured Keratinocytes.
○Chihaya Asakura1, Takeshi Matsui1 (1. Tokyo University of Technology)
[2P-597]Establishment of choroid plexus organoids and mechanical stimulation manipulation system using human iPS cells to elucidate mechanosensing & response in the choroid plexus
○Lisa Ikeda1,2, Tomohiro Tanaka2, Hibiki Endo3, Keiko Nonomura2,1 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Institute for Life And Medical Sciences, Kyoto University, 3. Graduate School of Biostudies, Kyoto University)
[2P-598]CDK9-55 promotes the process of muscle differentiation
○Makoto Nishikawa1, Yuki Nakayama2 (1. Kumamoto Univ, Grad. Sch. of Sci. and Tech., 2. Kumamoto Univ, Fac. of Adv. Sci. Tech.)
[2P-599]Single-cell dCas9-activation screen identifies hepatic maturation regulators with zonal resolution
○Atsuhiro Taguchi1,2, Alexandre Magalhães2, Denes Hnisz2, Alexander Meissner2 (1. Chiba University Graduate School of Medicine, 2. Max Planck Institute for Molecular Genetics)
[2P-600]Tension-induced enhancement of Six1 expression during preplacodal ectoderm differentiation from human iPSCs
○Seungtae Kim1, Ayumi Horikawa2, Takayoshi Yamamoto2, Tatuo Michiue1,2 (1. Dept. of Biol. Scis., Grad. Sch. of Sci., The Univ. of Tokyo, 2. Dept. of Life & Scis., Grad. of Arts & Scis., The Univ. of Tokyo)
[2P-601]Development of a novel method for cultivation and functional analysis of human pancreatic tuft cells.
○Tatsuya Kometani1, Kosuke Sakaguchi1, Hiroo Imai2, Ken Iwatsuki1 (1. Applied Bioscience, Tokyo Univ. of Agri., 2. Primate Res. Inst., Kyoto Univ.)
[2P-602]Smooth muscle cell differentiation of human myofibroblasts on type I collagen gel substrates
○Yuta Shimizu1, Takanori Kihara1 (1. The university of kitakyushu)
[2P-603]Prediction of Pancreatic β-cell Fate Conversion Factors Using CellOracle
○Hiroyuki Fukuda1, Ruslan Deviatiiarov1, Kenji Kamimoto3,4, Oleg Gusev1, Yasushi Okazaki1,2, Masahito Matsumoto1,2 (1. Intractable Disease Center, 2. Direct Cell Reprogramming for Regenerative Medicine, 3. Research Institute for Microbial Diseases, Osaka University, 4. Osaka University’s Premium Research Institute for Human)
[2P-604]RNA sensing of adenoviral transcripts could suppress osteoclast differentiation.
○Kazuhisa Nakashima1, Hisashi Ideno1, Komatsu Koichiro1, Teruhito Yamashita2, Akira Nifuji1 (1. Tsurumi University, 2. Matsumoto Dental University)
[2P-605]The mechanism of action of thyroid hormone on myogenic differentiation in Xenopus
○Marina Yamadera1, Daisuke Tsukamoto1,2, Takuya Matsuo1,2, Michihiko Ito1,2, Kei Tamura1,2 (1. Div. Biosci., Grad. Sch. Sci., Kitasato Univ, 2. Dept. Biosci., Sch. Sci., Kitasato Univ.)
[2P-606]A single-cell transcriptome approach revealed the function of BMP4 for mesoderm lineage-specification in time-dependent manner
○Wei Zhao1, Minoru Takasato1 (1. RIKEN Center for Biosystems Dynamics Research)
[2P-607]"Mapping and Functional Homology between C. elegans and Human at the Cellular Level through a Constitutive Model"
○Masaharu Obayashi1 (1. MetaCube Co.,Ltd.)
[2P-608]Analysis of iPS Cells Differentiation Mechanism based on Cell Cycle
○Masato Yoshizaki1, Tohru Sugawara1 (1. Graduate School of Medical Life Science, Yokohama City University)
[2P-609(2AS-03-03)]Transcriptional reprogramming in the early mouse embryos
○Mizuki Sakamoto1, Aoi Ito1, Sayaka Wakayama2, Hiroyuki Sasaki3, Teruhiko Wakayama2, Takashi Ishiuchi1 (1. Fac. of Life and Environ. Sci., Univ. of Yamanashi, 2. Advanced Biotechnology Center, Univ. of Yamanashi, 3. Div. of Epigenome, MIB, Kyushu Univ.)
[2P-610(2AS-06-02)]Mind the gap: Space inside eggs steers first few steps of life
○Sungrim Seirin-Lee1,2, Kazuhiro Yamamoto3, Akatsuki Kimura4 (1. KUIAS, Kyoto University, 2. Graduate School of Medicine, Kyoto University, 3. Hokkaido University, 4. NIG)
[2P-611]Hypoxia stress makes developmental robustness weakly by reducing cell competition function.
○Hikari Ukawa1, Yuki Akieda1, Tohru Ishitani1 (1. RIMD, Osaka University)
[2P-612]Analysis of pluripotency factors and Hippo signals in the early development of mouse polyploid embryos.
○Kaoru Fujino1, Sumito Matsuya2, Hiroyuki Imai3, Ken Takeshi Kusakabe3, Kiyoshi Kano1 (1. Laboratory of Developmental Genetics - Biomedical Science, Veterinary Medicine, Yamaguchi University, 2. Laboratory of Anatomy, Veterinary Medicine, Kagoshima University, 3. Laboratory of Anatomy, Veterinary Medicine, Yamaguchi University)
[2P-613]Transcriptomic Analysis to Identify Divergent Functions of Transposable Elements in Preimplantation Embryos
○Bo Zhang1 (1. Keio University)
[2P-614]Effects of endoplasmic reticulum stress induction by tunicamycin on the nucleolus in mouse preimplantation embryos.
○Masahiro Horizoe1, Kayanuma Taiga1, Bari MD Wasim1, Kishigami Satoshi1,2 (1. University of Yamanashi, 2. Center for advanced Assisted Reproductive Technologies)
[2P-615]Understanding human limb development using iPSC-derived limb bud mesenchyme.
○Ayume Nitta1 (1. Dept. of Regen. Sci., Grad. Sch. of Med., Univ. of Okayama)
[2P-616]Alteration of Morphogen Function by Membrane Binding
○Takayoshi Yamamoto1, Tatsuo Michiue1 (1. Univ. of Tokyo)
[2P-617]Quantitative analysis of the localization of Hr-Eph1 mRNA to the posterior region of ascidian embryos
○Ayumi Yoshikawa1, Naohito Takatori1 (1. Graduate School of Science Tokyo Metropolitan Univ.)
[2P-618]Identifying the reaction network for PAR polarization in C.elegans dorsal/ventral axis establishment
○Saito Ryunosuke1, Masatoshi Nishikawa1,2 (1. Grad. Sch. Sci&Eng., Hosei Univ., 2. Dep. Frontier Biosci., Hosei univ.)
[2P-619]Functional analysis of nucleolar protein NOL11 in mammals
○Miyu Kubota1, Kotoko Itabashi1, Kazashi Kato2, Tomohiro Kobayashi1, Keiji Kimura2, Shin-ichi Kashiwabara1, Yoshinori Kanemori1 (1. Faculty of Life and Environmental Sci., Univ. of Tsukuba, 2. TARA center, Univ. of Tsukuba)
[2P-620]Morphological characterization of Recql5 mutant early embryos using deep learning
○Makoto Hamaghchi1, Toshimi Yamanaka2, Satoru Iwata3,4,5,6, Miki Nagahara4, Takashi Iwamoto1,3,4 (1. Department of Biomedical Sciences, Graduate School of Life and Health Sciences, Chubu University, 2. Department of Robotic Science and Technology, Graduate School of Engineering, Chubu University, 3. Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, 4. Center for Education in Laboratory Animal Research, Chubu University, 5. College of Bioscience and Biotechnology, Chubu University, 6. Center for Mathematical Science and Artificial Intelligence, Chubu University)
[2P-621]The SIN-3 HDA-1 corepressor complex regulates embryonic development by suppressing the APL-1 expression in Caenorhabditis elegans
○Mitsuki Ohara1, Tasuku Hamasaki1, Hikaru Sasaki2, Shinji Ihara2, Masahiro Ito1, Yukihiko Kubota3 (1. Department of Bioinformatics, Graduate School of Life Sciences, University of Ritsumeikan, 2. Faculty of Bioresource Sciences, Prefectural University of Hiroshima, 3. Department of Bioinformatics, Collage of Life Science, University of Ritsumeikan)
[2P-622]Role of H3K9 methylation in mouse zygotic genome activation
○Ryo Maeda1, Makoto Tachibana1 (1. Osaka Univ.)
[2P-623]The NAD+ precursor nicotinamide mononucleotide improves mitochondrial function in bovine morula and increases the development into blastocyst.
○SHu Hashimoto1, Hideki Kitaji1, Yuki Takada1, Masaya Yamanaka2, Udayanga Gamage2, Hisataka Iwata3, Yuki Inoue3, Yoshiharu Morimoto2 (1. Osaka Metropolitan University, 2. HORAC Grand Front Osaka Clinic, 3. Tokyo University of Agriculture)
[2P-624(2PS-12-01)]De novo incorporating H3.3 during late mouse spermatogenesis
○Jianxi Li1,2, Masashi Hada1, Yuko Fukuda1, Erina Inoue1, Chizuko Koga1, Jun Hamazaki2, Shigeo Murata2, Julie Cocquet3, Yuki Okada1 (1. IQB, Tokyo Univ., 2. Department of Pharmaceutical Science, Tokyo Univ., 3. Université Paris Cité, INSERM, CNRS, Institut Cochin)
[2P-625]Establishment of in vitro implantation model using newly developed endometrial organoid
○Taishi Fujimura1, Isao Tamura1, Amon Shiroshita1, Norihiro Sugino1 (1. Department of Obstetrics and Gynecology Yamaguchi University Graduate school of Medicine)
[2P-626]The role of intracellular metabolism during migration in avian primordial germ cells
○Aika Nishina1, Akira Oikawa2, Yuji Atsuta1,3, Yoshiki Hayashi1,3, Daisuke Saito1,3 (1. Kyushu University Graduate School of Systems Life Sciences, 2. Kyoto University Graduate School of Agriculture, 3. Kyushu University Faculty of Science)
[2P-627]Small peptides regulate functional differentiation of accessory gland cells in Drosophila male
○Shinichi Otsune1, Chisato Shirakashi1, Mirai Matsuka1, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life, Natl. Sci. Tech., Okayama Univ.)
[2P-628]Analysis of species differences in the functional domain HMG box in the sex-determining gene Sry between mouse and human
○Riko Kawarada1,2, Atsumi Tsuji-Hosokawa1,3, Miho Terao1, Mika Hirabayashi1, Shuji Takada1,2 (1. Dept. of Systems BioMed., NCCHD, 2. NCCHD Dept. NCCHD, Grad. Sch. Med. Dent. Sci., TMDU, 3. Dept. Dev. Biol. Pediatr, Grad. Sch. Med. Dent. Sci., TMDU)
[2P-629]CDYL2 regulates the differentiation of spermatogonial stem cells through the modulation of Rheb expression
○Aya Yoshida1, Hozumi Nomura1, Tokoku Iwamori2,3, Naoki Iwamori1,3 (1. Kyshu Univ. Graduate School of Bioresource and Bioenvironmental Sciences., 2. Restart Postdoctoral Research Fellowships., 3. Kyshu Univ. School of Agriculture.)
[2P-630]Search for molecules that induce gelation of post-ejaculate uterine fluid
○Yu Matsumoto1, Ban Sato1, Kenji Miyado2, Natsuko Kawano1 (1. Meiji University, 2. National Research Insitute for Child Health and Development)
[2P-631]Wnt/β-catenin signaling induces cell death in avian primordial germ cells
○Ayaka Matsuo1, Yuji Atsuta1,2, Yoshiki Hayashi1,2, Daisuke Saito1,2 (1. Graduate School of System Life Science, Kyushu Univ., 2. Graduate School of Science, Kyushu Univ.)
[2P-632]Tracking Chromatin Dynamics during Sperm Nuclear Condensation
○Masashi Hada1, Yuko Fukuda1, Chizuko Koga1, Erina Inoue1, Yasuhiro Fujiwara1, Yuki Okada1 (1. Institute for Quantitative Biosciences, The University of Tokyo)
[2P-633(2MS-06-02)]The development of systems to understand the heterogeneity of mouse spermatogonial stem cells
○Shinnosuke Suzuki1,2,3, Shosei Yoshida1,2, Brian P Hermann3, Kuniya Abe4 (1. National Institute for Basic Biology, 2. The Graduate University for Advanced Studies, 3. University of Texas at San Antonio, 4. Riken BioResource Research Center)
[2P-634]Notch signaling causes cell death in avian primordial germ cell
○Asuka Ryuno1, Yuji Atsuta1,2, Yoshiki Hayashi1,2, Daisuke Saito1,2 (1. Kyushu University, 2. Kyushu University)
[2P-635]Possible involvement of the LdMasc partial sequence, a male-oriented gene found in large numbers in the Lymantria dispar genome, in determining female sex.
○KISUKE SHOJI1, MASATAKA SUZUKI1 (1. The University of Tokyo)
[2P-636]Effect of microRNAs contained in intrauterine EVs on embryonic and endometrial gene expressions in low-fertility cows.
○Rei Ichikawa1, Koji Kimura2, Sho Nakamura1, Satoshi Ohkura1, Shuichi Matsuyama1 (1. Graduate School of Bioagricultural Sciences, Nagoya University, 2. Graduate School of Environmental and Life Science, Okayama University)
[2P-637]Kallikrein 1 mediates seminal protein degradation in uterine fluid.
○Manato Sunamoto1, Ban Sato1, Natsuko Kawano1 (1. Meiji Univ.)
[2P-638]Verification of the mechanism by which mutant mitochondrial DNA is lost from the female mouse germ line
○Kanako Ito1, Haruma Sasaki1, Nanako Yasuhara1, Kazuto Nakada2, Kaori Ishikawa2 (1. Master's Program in Biology, University of Tsukuba, 2. Institute of Life and Environmental Sciences, University of Tsukuba)
[2P-639]Functional analysis of barrier-to-autointegration factor-like protein (BAF-L)
○YUN-A LEE1, Yukiya Otaka1, Taro Mannen1, Shinji Ito2, Toshiya Hayano1 (1. Ritsumeikan Univ., 2. Kyoto Univ.)
[2P-640]Development of reproductive engineering techniques in cancer- and senescence-resistant rodent, naked mole-rat
○Yoshimi Kawamura1, Karin Okumura1, Yusuke Suzuki1, Kaori Oka1, Kyoko Miura1 (1. Kumamoto University)
[2P-641]Autophagy-dependent elimination of egg chambers in Drosophila ovaries and acquisition of heat tolerance
○Hayato Kikuoka1, Namika Matsumoto1, Ayaha Tanaka1, Moeka Koyama1, Kanako Omoteda1, Naoya Yoshida1, Junki Watanabe2, Masanori Mukai1,2 (1. Dept .of Biol.,Fac .of Sci .eng.,Konan Univ., 2. Grad .Sch.of Nat . Sci .,Konan Univ.)
[2P-642]In vitro spermatogenesis in the absence of Leydig cells using ΔFLE mouse
○Miharu Yoshida1, Yu Ishikawa-Yamauchi1, Takuya Sato1, Miki Inoue2, Kanako Shima2, Yuichi Shima2, Takehiko Ogawa1 (1. Department of Regenerative Medicine, Yokohama City University, Yokohama, Japan, 2. Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Fukuoka, Japan)
[2P-643]Analysis of Gm614 knockout mice
○Arisa Tanigawa1, Yoshiki Miyasaka1, Tomoko Tokunaga1, Manami Nishimura1, kazuki nakao1 (1. OSAKA UNIVERSITY)
[2P-644]Identification of genes involved in sex differentiation of the gonad by transcriptome analysis using gynandromorphic silkworms
○Masataka Suzuki1, Kyoko Ishida1, Takeshi Yokoyama2 (1. UTokyo, 2. TUAT)
[2P-645]Comparison of expressed genes in monolayer and spheroid-cultured bovine luteal cells by comprehensive analysis.
○Azusa Tokuriki1, Sayaka Kubota1, Hisataka Iwta 2, Kohei Kawano1, Koji Kimura1 (1. Graduate School of Environmental, Life, Natural and Technology, Okayama University, 2. Department of Animal Science, Tokyo University of Agriculture)
[2P-646]Identification of a novel spermatid-activating factor by using the C. elegans serine protease inhibitor SWM-1
○Rina Tatsumi1, Hitoshi Nishimura1 (1. Setsunan university)
[2P-647]Effect of embryonic hypoxia on caudal fin regeneration in zebrafish larvae
○Shunta Yamagishi1, Hiroyasu Kamei1 (1. Kanazawa University)
[2P-648]Acto3D, an open-source user-and budget-friendly volume rendering software for high-resolution 3D fluorescence imaging
○Kenta Yashiro1, Naoki Takeshita1,2, Tomoko Iehara2 (1. Anatomy, Kyoto Pref Univ Med, 2. Pediatrics, Kyoto Pref Univ Med)
[2P-649(2AS-06-06)]The vertebrate body plan and the mid-embryonic conservation: insights from a comparative single-cell level transcriptome analysis
○Masahiro Uesaka1, Shigeru Kuratani2, Naoki Irie3 (1. Tohoku University, 2. RIKEN BDR, 3. SOKENDAI)
[2P-650]SSBD: Global sharing of bioimaging data
○Koji Kyoda1, Hiroya Itoga1, Yuki Yamagata2,3, Miguel Miranda-Miranda1, Haruna Yamamoto1, Emi Fujisawa1, Yukako Tohsato1,4, Shuichi Onami1,3 (1. RIKEN BDR, 2. RIKEN BRC, 3. RIKEN R-IH, 4. Ritsumeikan Univ.)
[2P-651]Expression of Muscle Proteins Accompanying Repair and Regeneration from Spinal Cord Injury
○Kosei Toki1, Hiroyuki Sasakura2,3, Dai Oishi2,4, Kosei Takeuchi2,3, Naruki Sato1,5 (1. Graduate School of Science and Engineering, Chiba University, 2. Department of Medical Cell Biology, School of Medicine, Aichi Medical University, 3. Medical Research Creation Center, Aichi Medical University, 4. Emergency and Critical Care Medicine, School of Medicine, Aichi Medical University, 5. Graduate School of Science, Faculty of Science, Chiba University)
[2P-652]Role of vesicle transport regulator gene Vps52 and its related genes during mouse embryogenesis
○Michihiko Sugimoto1, Kuniya Abe2 (1. Hyogo Medical University, 2. RIKEN)
[2P-653]Revealing Evolutionary Constraints in Development by Deciphering Robust Cell Types in Vertebrate Embryo
○Wenxin Zeng1, Jason Cheok Kuan Leong2, Masahiro Uesaka3, Takafumi Ikeda4, Naoki Irie2 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. Research Center for Integrated Evolutionary Science, SOKENDAI, 3. Department of Ecological Developmental Adaptability Life Sciences, Graduate School of Life Sciences, Tohoku University, 4. Institute for Protein Dynamics, Kyoto Sangyo University)
[2P-654]Expression of the E93 gene and its function in adult development in Gryllus bimaculatus as a model for hemimetabolous insects
○Tomoaki Inoue1, Yoshiyasu Ishimaru2, Kohei Kawamoto4, Shintaro Inoue3, Takahito Watanabe3, Sumihare Noji3, Taro Mito3 (1. Tokushima Univ., Graduate School of Sciences and Technology for Innovation, Tokushima University , 2. Tokushima Univ., Graduate School of Technology, Industrial and Social Sciences, 3. Tokushima Univ., Bio-Innovation Research Center, 4. Tokushima Univ., Graduate School of Advanced Technology and Science, Tokushima University)
[2P-655]Comparative assessment of blue and cyan fluorescent protein variants in zebrafish embryos
○Aiko Ichinose1, Tomohiro Kanzaki1, Yusuke Kamachi1 (1. Kochi university of technology)
[2P-656]Development of an automated sampling device and acquisition of high-resolution time series data for the elucidation of the dynamics of the gut microbiome.
○Rina Kurokawa1, Hiroaki Masuoka1, Lena Takayasu1, Wataru Suda1 (1. RIKEN)
[2P-657]Elucidating the process of bacterial vaginosis pathogenesis using state transitions based on pseudotime reconstructing and the energy landscape
○Daiki Kumakura1,2, Ryohei Shimizuhata1, Shinji Nakaoka3 (1. Grad. Life Sci., Hokkaido Univ., 2. iTHEMS, RIKEN, 3. FAC. Adv. Life Sci., Hokkaido Univ.)
[2P-658]Host-derived interleukin-33 influences sex differences in gut microbiota composition and function
○Miho Akimoto1, Takao Susa1, Noriyuki Okudaira1, Harumi Hisaki1, Masayoshi Iizuka2, Mimi Tamamori-Adachi1 (1. Dept. of Biochem., Teikyo Univ. Sch. of Med., 2. Med. Educ. Ctr., Teikyo Univ. Sch. of Med.)
[2P-659]Bacterial flora analysis of cecal and rectal feces in mice exposed to whole body radiation
○Takamasa Nagai1, Kanako Yamanouchi1, Masaru Yamaguchi2, Takakiyo Tsujiguchi3, Katsuhiro Itoh3, Mitsuru Chiba1 (1. Dept. of Biosci. & Lab. Med., Grad. Sch. of Health Sci., Univ. of Hirosaki, 2. Dept. of Radio. Sci., Grad. Sch. of Health Sci., Univ. of Hirosaki, 3. Educ. Center Disas. Radiat. Emer. Med., Univ. of Hirosaki)
[2P-660]Comparative Genomic Analysis of Long-term Resident Bifidobacteria Unique to Individual Guts
○Ayana Shinomiya1,2,3, Tomoya Tsukimi1, Tsubasa Watabe1, Yuki Yoshida1, Haruo Suzuki1,2, Kumiko Kato4, Tshitaka Odamaki4, Mitsuhiko P Sato5, Yoshitoshi Ogura6, Shinji Fukuda1,3 (1. Inst. Adv. Biosci, Keio Univ., 2. Fac. Environ. Info. Stud, Keio Univ., 3. KISTEC., 4. Innov. Res. Inst., Morinaga Milk Indust., 5. Kazusa DNA Res. Inst., 6. Kurume Univ. Sch. Med.)
[2P-661]Development of a novel coculture method for intestinal organoids and gut bacteria
○Atsuki Imai1, Takahashi Mikako2, Toyoyuki Hashimoto2, Nobuo Sasaki1 (1. Gunma Univ., 2. Shimadzu Corp.)
[2P-662]Analysis of Growth, Biofilm Formation, and Enterotoxin Production of Staphylococcus aureus under Different Conditions
○Dong-Liang Hu1, Zuo Hu1, Zhihou Zhu1, Kanako Okada1, Minami Oshima1, Hisaya Ono1, Shouhei Hirose2, Yukiko Kudo3 (1. Kitasato University School of Veterinary Medicine, 2. National Institute of Health Sciences, 3. Hoshi University)
[2P-663]Identification of microbiota associated with Polypedilum sp. (Diptera; Chironomidae), a midge adapted to the highly acidic environment
○Eita Nakanishi1, Richard Cornette2, Shimura Sachiko2, Kikawada Takahiro1,2 (1. The University of Tokyo, 2. National Agriculture and Food Research Organization)
[2P-664]Comparative analysis of the mechanism of diapause induction in nematodes, Caenorhabditis elegans and its sister species Caenorhabditis inopinata
○Ryo Iitsuka1, Oomura Shun1, Nami Haruta1, Asako Sugimoto1 (1. Tohoku University)
[2P-665]Analysis of the clock protein complex during differentiation of mouse embryonic stem cells.
○Akira Sugimoto1, Yoshiki Tsuchiya1, Yasuhiro Umemura1, Kazuhiro Yagita1 (1. Department of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine)
[2P-666]The involvement of the gonads in the circadian rhythms of corticosterone secretion in mice.
○Takao Susa1, Tomoko Okada1, Noriyuki Okudaira1, Miho Akimoto1, Masayoshi Iizuka1,2, Mimi Tamamori-Adachi1 (1. Dept. of Biochem., Teikyo Univ. Sch. of Med., 2. Med. Educ. Ctr., Teikyo Univ. Sch. of Med.)
[2P-667]Regulation of brain parenchymal homeostasis by glial cells around the ventricles
○Megumi Uno1, Junnosuke Nakamura1, Fuminori Tsuruta2 (1. Doctral Program in Biology, University of Tsukuba, 2. Institute of Life and Environmental Sciences, University of Tsukuba)
[2P-668(2AS-15-04)]Complex Formation of Immunoglobulin Superfamily Molecules Side-IV and Beat-IIb Regulates Synaptic Specificity
Jiro Osaka2, Shogo Akino1, Atsushi Sugie2, Satoko Hakeda3, ○Takashi Suzuki1 (1. Institute of Science Tokyo, 2. Niigata University, 3. National Yokohama University)
[2P-669]The Role of Synapse Formation in Axon Target Determination in Drosophila Photoreceptor Neurons
○Satoko Hakeda-Suzuki1,3, Jiro Osaka2, Takashi Suzuki3 (1. Yokohama National University, 2. Niigata University, 3. Institute of Science Tokyo)
[2P-670(2MS-01-05)]CD63, an exosome-related gene, contributes to the generation of basal neural progenitors to promote cortical expansion
○Boyang An1, Tomonori Kameda2, Fumihiro Morishita1, Mizuki honda1, Kinichi Nakashima2, Takuya Imamura1 (1. Hiroshima Univ., 2. Kyushu Univ.)
[2P-671]The transmembrane protein teneurin-4 drives myelination by promoting actin depolymerization in oligodendrocytes
○Binri Sasaki1, Chikako Hayashi1, Nobuharu Suzuki1 (1. Graduate School of Medical and Dental Science, Tokyo Medical and Dental University)
[2P-672(2PS-17-05)]Cryo-EM Structures of QRFP-GPR103-Gq complex reveal the activation mechanism of GPR103, which is involved in homeostasis.
○Aika Iwama1, Ryoji Kise2, Hiroaki Akasaka1, Fumiya K Sano1, Hidetaka S Oshima1, Asuka Inoue2,3, Wataru Shihoya1, Osamu Nureki1 (1. The University of Tokyo, 2. Tohoku University, 3. Kyoto University)
[2P-673(2MS-01-06)]Spatially Resolved Single-cell Analysis Reveals Human-specific Early Prenatal Specification of Primary Visual Cortex
○Xuyu Qian1,2, Kyle Coleman3, Shunzhou Jiang3, Andrea J Kriz1,2, Jack H Marciano1,2, Chunyu Luo3, Carsen Stringer4, Mingyao Li3, Christopher A Walsh1,2 (1. Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. , 2. Howard Hughes Medical Institute, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. , 3. Statistical Center for Single-Cell and Spatial Genomics, Department of Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA, 4. Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA)
[2P-674]Roles of lysosomal exocytosis in neocortical development
○Boqiao Chen1, Naoya Yuizumi1, Koji Oishi1, Yukiko Gotoh1,2 (1. The Univ. of Tokyo, 2. WPI-IRCN, The Univ. of Tokyo)
[2P-675]Molecular mechanisms that regulate morphogenesis of feedback neuron in fly visual system
○Misaki Izawa1, Takumi Suzuki1 (1. Dept. of Biol., Grad. Sch. of Sci. and Eng., Ibaraki Univ.)
[2P-676(2AS-15-03)]GAP-43, a neuronal growth-related protein, is an IDR
○MICHIHIRO IGARASHI IGARASHI1, Toshiyuki Takasugi1, Kentaro Okuyama2, Shinsuke Shibata2, Noriyuki Kodera3 (1. Dept Neurochemi Mol Cell Biol, Niigata Univ, 2. Niigata Univ, 3. Kanazawa Univ)
[2P-677]A potential role of ER stress in the neurogenic-to-astrocytic transition of neural progenitor fate in the developing mouse cerebral cortex
○Masatake Sasaki1, Yukiko Gotoh1,2, Koji Oishi1 (1. Grad. Sch. of Pharm. Sci., The University of Tokyo, 2. IRCN, Univ. of Tokyo)
[2P-678]Sequence difference responsible for ubiquitination in microtubule-severing enzymes katanin and katanin-like
○Tomoki Shigemura1, Kensuke Hayashi1 (1. Sophia University)
[2P-679(2PS-17-06)]Developing multiplex imaging platforms for deciphering Ca2+-dependent biochemical signaling in the brain health and disease
○Hajime Fujii1, Keisuke Ota1, Yayoi Kondo1, George Cai2, Richard Song3, Haobo Song1, Hayato Kondo1, Masatoshi Inoue4, Shin-ichiro Horigane5, Sayaka Takemoto-Kimura5,6, Haruhiko Bito1 (1. Dept of Neurochemistry, Graduate School of Medicine, The University of Tokyo, 2. Dept of Physics, Harvard University, 3. Dept of Neuroscience, Vanderbilt University, 4. Dept Radiology, Wash U St. Louis, 5. Res. Inst. of Envrm. Med. (RIEM), Nagoya Univ., 6. Dept. of Molecular/Cellular Neurosci., Nagoya University Graduate School of Medicine)
[2P-680]Regulation of adult neural stem cell establishment by FGF binding protein 3
○Caiwei Li1, Daichi Kawaguchi1, Yukiko Gotoh1 (1. University of Tokyo)
[2P-681]Identification and characterization of novel stem cell population in neocortex development.
○Takayuki Kimura1, Koyomi Shimamoto1, Koichiro Irie2,3, Yuta Furusho2, Anzu Kuriyama1, Shoko Yoshizawa1, Naoto Ohte1, Carina Hanashima2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Arts and Sciences, School of Education, Waseda University, 3. Graduate School of Medicine, Osaka University)
[2P-682]Neuronal pathways from the epidermal sensory neurons derived from the primitive olfactory placode in the larva of the ascidian Ciona intestinalis type A
○Kenichi Kiyoyama1, Takehiro G. Kusakabe1,2 (1. Dept. of Biol., Grad. Sch. of Nat. Sci., Konan Univ., 2. Institute for Integrative Neurobiology, Konan Univ.)
[2P-683]Analysis of Foxg1 and RP58 functions in reptilian cortical development using CRISPR/Cas9 knockout gecko embryos
○Shoma Ishizuka1,2, Takuma Kumamoto2, Takaya Abe4, Hiroshi Kiyonari4, Hiroaki Norimoto5, Riho Kobayashi5, Koki Kotake5, Chiaki Maruyama2, Carina Hanashima3 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Developmental Neuroscience Project, Tokyo Metropolitan Institute of Medical Science , 3. Faculty of Education and Integrated Arts and Sciences, Waseda University, 4. Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, 5. Neuroethology group, Graduate School of Science, Nagoya University)
[2P-684]Intracellular localization analysis of ArhGAP21 RhoGAP isoforms expressed in mouse embryonic brain
○Zen Kouchi1, Koji Inui1 (1. Institute for Developmental Research, Aichi Developmental Disability Center)
[2P-685]Insights into the origin of neurons from functional analysis of “neurogenic” transcription factors in ctenophores
○Minato Miyake1, Hiroshi Watanabe1 (1. OIST Evolutionary Neurobiology Unit)
[2P-686]Neural circuit for regulating gut immunity in Drosophila
○Ayane Yagi1, Megumi Oya1, Dat Quang Nguyen1, Naoyuki Fuse1, Shoichiro Kurata1 (1. Molecular Genetics, Grad. Sch. of Pharm. Sci., Tohoku Univ.)
[2P-688]GnRH-related signals accelerate forgetting of olfactory learning by erasing sensory memory trace
○Yuuki Onishi1, Mary Arai2, Jamine H Teo1, Tomohiro Kitazono1, Takeshi Ishihara1,2 (1. Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan, 2. Department of Biology, Faculty of Science, Kyushu University, Fukuoka, Japan)
[2P-689(2PS-17-03)]Thermo-receptor candidate GPCR and thermal responsive neural circuit in temperature response of C. elegans
○Hiromu Ueka1, Chinatsu Morimoto1,2,3, Chie Miyazaki1, Kohei Ohnishi1,2,3, Tohru Miura1,2,3, Akane Ohta1,2,3, Atsushi Kuhara1,2,3,4 (1. Dept. Biol. Facul. Sci & Engineer. Konan Univ. , 2. Dept.Biol. Grad. Sch. Sci. Konan Univ., 3. Inst. of Integral NeuroBiol. Konan Univ. , 4. PRIME AMED)
[2P-690]Do individual termite movements reflect nest sturcture differences?
○Kensei Kikuchi1, Nobuaki Mizumoto2 (1. Okinawa Institute of Science and Technology, 2. Auburn University)
[2P-691]Alteration in anxiety behavior due to deficiency of a metallophosphoesterase domain-containing protein
○Shin-ichiro Honda1, Miku Ishikawa1, Hazuki Mizukami1, Yusuke Murata1, Ohe Kenji1, Munechika Enjyoji1, Chise Taniguchi1 (1. Fukuoka university)
[2P-692]Establishment of CMT4B1 model through mtm knockdown and elucidation of the molecular mechanisms
○Aya Hitomi1, Kazuki Shibutani1, Hideki Yoshida1 (1. KYOTO INSTITUTE OF TECHNOLOGY)
[2P-693]Effect of caffeine on low compartment residence time of zebrafish
○Ayako Ichimura1, Hideaki Tomura2 (1. Meiji Univ, Graduate Schoolof Agriculture, Department of Life Sciences, 2. Meiji Univ, Institute of Endocrinology)
[2P-694]Density-dependent growth control mechanisms mediated by serotonin and lateral line in Axolotl, Ambystoma mexicanum.
○Haruka Axolotl Sugiyama1, Santako Fuzzy-navel1, Ryuki Tatsuoka3, Taro Axolotl2, Yoshichika Yokoe4 (1. HAL lab, 2. HAL lab farm, 3. Amblystoma lab, 4. SciMoun technology)
[2P-695]Identification of genes involved in long-term memory maintenance in Drosophila
○Takehito Satoh1, Takaomi Sakai1 (1. Tokyo Metropolitan University)
[2P-696]Analysis of brain regions responsible for various social behaviors in autism spectrum disorder model mice
○Ran Ookawa1, Aika Sakamoto2, Shouji Kawano1, Naoto Yamazaki1, Shigeo Uchino1,2 (1. Graduate School of Science and Engineering, Teikyo University, 2. Department of Biosciences, School of Science and Engineering, Teikyo University)
[2P-697]Functional analysis of eutherian -specific retrotransposon-derived genes Sirh4, 5, 6
○Yoshifumi Fujioka1,2,3, Hirosuke Shiura4, Masayuki Ishii3, Ryuichi Ono5, Hikaru Ito6, Yoshikazu Hirate2, Tutomu Endo8,2, Masami Kanai2, Tomoko Kaneko-Ishino7, Fumitoshi Ishino3,2 (1. RIKEN IMS, Non-coding genomics, 2. Dept Experi Animal, Inst of Res Tokyo Med Dent Univ (TMDU), 3. Dept Epigen, Res Inst Tokyo Med Dent Univ (TMDU), 4. Fac Life and Enviro Sci, Yamanashi Univ , 5. Cent Biol Safety and Res, Nat Inst Health Sci, 6. Div of Experi Animal, Med, Kagawa Univ, 7. Fac Nurs, Med, Tokai Univ, 8. Applied Gen, Fac agri, Tokyo Univ)
[2P-698(2PS-08-03)]Neuroscience of mosquito hearing – investigating a potential new target for vector control -
○Takuro Ohashi1,2, YiFeng Y.J. Xu1,2, Shunsuke Shigaki3, Yukiko Nakamura1,2, Tai-Ting Lee1,2, YuMin M. Loh1,2, Emi Mishiro2, Daniel F. Eberl4, Matthew P. Su1,2,5, Azusa Kamikouchi1,2,5 (1. Grad. Sch. Sci., Nagoya Univ., 2. ITbM, Nagoya Univ., 3. Prin. Informatics Res. Div., Nat. Inst. Informatics, 4. Dept. Bio., Univ. Iowa,, 5. IAR, Nagoya Univ.)
[2P-699]Stress Response in a Transgenic Mouse Expressing a Human-Specific Alpha-1 Adrenergic Receptor (ADRA1A) Isoform in Astrocytes
○Yumi Miki1, Ririka Morimoto1, Kazuma Nakatani3, Yusuke Suenaga4, Hiromu Monai1,2 (1. Graduate School of Humanities and Sciences, Ochanomizu University, Tokyo, Japan, 2. Department of Biology, Faculty of Science, Ochanomizu University, Tokyo, Japan, 3. Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan, 4. Laboratory of Evolutionary Oncology, Chiba Cancer Center Research Institute, Chiba, Japan)
[2P-700]Functional analysis of neural circuits driving escape behavior selection in response to aversive stimuli in Drosophila larvae
○Izuki Watanabe1, Yusaku Hashimoto2, Shiina Takano2, Suguru Takagi2, Akinao Nose1,2 (1. Dept. Physics, Grad Sch of Sci, Univ of Tokyo, Japan, 2. Dept. Complex Sci and Eng, Grad Sch of Frontier Sci, Univ of Tokyo, Japan)
[2P-701]dve enhancer-responsive cells involved in the regulation of male courtship behavior in Drosophila
○Sayaka Takata1, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life, Natl. Sci. Tech., Okayama Univ.)
[2P-702]Gossypetin protects Lipopolysaccharide-Induced Systemic Inflammation in HT22 Mouse Hippocampal Neuronal Cells
○Seung Jun Yoo1, Zae Young Ryoo (1. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea)
[2P-703]Mutations in Ca2+ binding domains of Synaptotagmin 7 altered short-term memory during Pavlovian conditioning in Drosophila
○Akira Sakurai1, Motojiro Yoshihara1 (1. Natl. Inst. of Information and Communications Technology)
[2P-704]Involvement of the Drosophila yata gene that is related to Alzheimer’s disease in the metabolism, growth, and longevity signal
○Konosuke Sato1, Ami Asano1, Masaki Sone1 (1. Toho university)
[2P-705]Null mutants of the Drosophila yata gene that is related to the Alzheimer's disease show impaired lipid droplet formation
○Hayato Ichinosawa1, Shunsuke Murakoshi1, Okuto Kuniyasu1, Aoi Saito1, Kota Akimoto1, Shota Iwasawa1, Emiko Suzuki2, Masaki Sone1 (1. Toho university, 2. National Institute of Genetics)
[2P-706]Mitochondrial metabolic factor in cold acclimation of C. elegans
○Moe Tezuka1, Misaki Okahata1, Akane Ohta1,2, Atsushi Kuhara1,2 (1. Faculty of Science and Engineering Konan University & Institute for Integrative Neurobiology, Kobe, Japan, 2. PRIME, AMED)
[2P-707]Cyclic phosphatidic acid derivative is a promising therapeutic agent candidate for frontotemporal dementia
○Nami Yamamoto1, Mari Gotoh2, Yasunori Miyamoto1,3, Kei Hashimoto3 (1. Graduate School of Humanities and Sciences, Ochanomizu University, 2. Faculty of Medical Technology, Teikyo University, 3. Institute of Human Life Science, Ochanomizu University)
[2P-708]Sex-dependent seizure susceptibility in ASH1L mutants: Mechanisms and insights
○Haruki Higashimori1, Megha Jhanji1, Carin Papendrop1, Brian Kavanaugh2, Elizabeth Nolan1, Carrie Best1, Jennifer Elacio1, Luis Golcouria1, Sofia Lizarraga1, Judy Liu1 (1. Department of MCB, Brown University, 2. Pediatric Neuropsychology, Emma Pendleton Bradley Hospital)
[2P-709]Expression levels of ALS-linked genes NEK1 and ALS2 affect cell viability and neuronal phenotypes
○Haruka Yudahira1, Kai Sato2, Kento Shimakura3, Mitsuru Ishikawa4, Asako Otomo3, Shinji Hadano3 (1. Tokyo Metropolitan Neurological Hospital(Tokyo Met. Neurol. Hosp.), 2. RIKEN Center for Brain Science(RIKEN, CBS), 3. Department of Phsiology, Tokai University School of Medicine(Dept. Physiol., Tokai Univ. Sch. Med.), 4. ivision of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University(Div CNS Regene & Drug Disco, ICBS, Fujita Health Univ))
[2P-710]Elucidation of molecular pathogenesis of with pentosidine accumulation
○Azuna Ozawa1, Toriumi Kazuya2, Shimada Tadayuki3, Miyashita Mitsuhiro4, Itokawa Masanari2, Arai Makoto2 (1. Niigata University Graduate school of Medical and Dental Sciences Molecular and Cellular Medicine Major, 2. Tokyo Metropolitan Institute of Medical Science Schizophrenia Research Project, 3. Tokyo Metropolitan Institute of Medical Science Child Brain Project, 4. Tokyo Metropolitan Institute of Medical Science Research Center for Social Science & Medicine (RCSSM) Unit for Mental Health Promotion)
[2P-711]Effect of phosphorylation of Thr212 and Ser214 on the microtubule-binding ability of tau
○Mika Kashiwagi1, Rinaho Nakata2, Hiroaki Misono2, Tomohiro Miyasaka3 (1. Doshisha University (Life & Medical Science), 2. Doshisha University (Brain Science), 3. Nihon University)
[2P-712]Relationship between nucleic acid structures and neuronal dysfunction in cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS).
○Kenta Kudo1, Karin Hori1, Norifumi Shioda1 (1. Department of Genomic Neurology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University)
[2P-713]Fish oil-derived 2-mono-DHA glycerol improves cognitive decline dependently of GLP-1 signal
○Kohei Kawano1, Eriko Taniguchi1, Naoki Fujimoto2, Yuta Tsurumi2, Kondo Eriko2, Yukihiro Takase2, Kousaku Ohinata1 (1. Graduate School of Agriculture, Kyoto University, 2. DyDo DRINCO, INC.)
[2P-714]Relationships among Alzheimer's disease progression, epigenomic status, and APOE genotype by public data analysis
○Kosei Honda1, Akinori Awazu1 (1. Hiroshima University)
[2P-715]Roles of oxidative stress-dependent reduction of endogenous retroviruses in HT22 cells
○Yuzuki Kasai1, Toru Mizuki2, Taku Nedachi1 (1. Graduate School of Life Sciences, Toyo University, 2. Bio-Nano Electronics Research Center, Toyo University)
[2P-716]Reduced function of endoplasmic reticulum aminopeptidase 1 elicits anxiety disorder-like symptoms.
○Yoshikuni Goto1, Takahiro J Nakamura2, Mizuki Sugiyama2, Akira Hattori3, Kenji Ogawa4, Masafumi Tsujimoto1 (1. Teikyo-Heisei Univ., 2. Meiji Univ., 3. Kyoto Univ., 4. Nihon Univ.)
[2P-717]Development of an open neuronal cell culture device for localized collection of axons
○Bingbing Wang1, Yuta Murakami1, Keiko Nishijima2, Asako Otomo2,3, Shinji Hadano2,3, Hiroshi Kimura1,3 (1. Dept. of Mech., Tokai Univ. Sch. Eng., 2. Dept. of Physiol., Tokai Univ. Sch. Med., 3. MNTC, Tokai Univ.)
[2P-718]Aromatic-turmerone analogues activate chaperone-mediated autophagy through the persistent activation of p38
○Kensuke Motomura1, Boateng Alex2, Masaharu Sugiura2, Natsuko Hitora1, Yuki Kurauchi1, Hiroshi Katsuki1, Takahiro Seki1,3 (1. Department of Chemico-Pharmacological Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University , 2. Graduate School of Pharmaceutical Sciences, Sojo University, 3. Department of Pharmacology, Faculty of Pharmaceutical Sciences, Himeji Dokkyo Univesity)
[2P-719]Investigating the physiological significance of ALS-related protein VAP MSP domain
○Mizuki Tando1, Kosuke Kamemura2, Misako Okumura1, Takahiro Chihara1 (1. Hiroshima University,Graduate School of Integrated Sciences for Life, 2. University of Texas,Southwestern Medical Center,Department of Molecular Genetics)
[2P-720]Hyperactivity of colonic myenteric plexus in a mouse model of irritable bowel syndrome
○Ken Ueda1, Kazuki Harada1, Yuri Osuga1, Hiromu Monai2, Takashi Tsuboi1 (1. Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, Japan, 2. Department of Biology, Faculty of Science, Ochanomizu University, Ohtsuka, Bunkyo-Ku, Tokyo 112-8610, Japan)
[2P-721]Morphological analysis of neurons in the neocortex in autism spectrum disorder model mice
○Shuma Yamaguchi1, Momoka Kawabata1, Shouji Kawano1, Yang Yang2, Wu TongHui2, Kenta Tozaki1, Shigeo Uchino1,2 (1. Graduate School of Science and Engineering, Teikyo University, 2. Department of Biosciences, School of Science and Engineering, Teikyo University)
[2P-722]Relief of neuropathic pain in mice by an antibody with high affinity for cell adhesion molecule 1 on nerves
○Fuka Takeuchi1, Man Hagiyama2, Akihiko Ito1,2 (1. Div. Mol. Pathol., Grad. Sch. of Med. Sci., Kindai Univ., 2. Dept. Pathol., Fac. Med., Kindai Univ.)
[2P-723]Identification of functional domains in ATXN1 for an alternative splicing
○Ai Ohki1, Yoshihiro Kino1, motoaki Yanaizu1 (1. Meiji Pharmaceutical Univ.)
[2P-724]Single cell and spatial analysis of brain organoids derived from patients with high-risk CNVs for mental disorders
○Yusuke Mizuno1, Masahide Seki1, Akinori Kanai1, Junko Zenkoh1, Yuko Arioka2, Hiroki Okumura2, Norio Ozaki2, Yutaka Suzuki1 (1. Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Pathophysiol. Mental., Grad. Sch. of Med., Nagoya Univ.)
[2P-725]Collection and quantification of axon-specific RNA samples using a neuronal polarity control device
○YOSUKE IIDA1, Yuta Murakami2, Bingbing Wang2, Asako Otomo3, Hiromi Takahashi3, Shinji Hadano3, Hiroshi Kimura4 (1. Sch.of Eng., Tokai univ., 2. Grad.Sch. of Eng., Tokai univ., 3. Dept.of Physiol,.Tokai univ.Sch Med., 4. MNTC.,Tokai univ.)
[2P-726]Heterogeneity of degenerating retinal ganglion cells after optic nerve injury
○Serika Hosoi1, Mika Takaraga-Iemata1, Sumiko Kiryu-Seo2, Osamu Hori1 (1. Dept. Neuroanat. Kanazawa Univ. Grad. Sch. Med. Sci., 2. Dept. Funct. Anat. & Neurosci. Nagoya Univ. Grad. Sch. Med.)
[2P-727]Human chromosome structure simulation modeling to approach disease mechanisms
○Naoko Tokuda1 (1. Japan Society for the Promotion of Science(Nagoya Univ.))
[2P-728]Human iPSCs derived glial progenitor cells (iGRPs) improve motor function in a rat model of ALS.~Developing a new treatment for ALS~
○Natsumi Nagashima1, Litong Liu1, Mitsuki Kanaya1, Saya Okimura1, Mitsuru Inamura1 (1. REPROCELL Inc.)
[2P-729]Hydrogen rich water-induced thinning of mucin layer with increasing in mucin degrading bacterium in the small intestine
○Yui Ueta1,2, Akane Yokoyama1,2, Masumi Iketani1, Satoshi Aokage1, Masahumi Ito1, Hideo Kawaguchi2, Ikuroh Ohsawa1 (1. Biol Proc Aging, TMIG, 2. Grad Sch Life Sci, Toyo Univ)
[2P-730]Molecular hydrogen suppresses progression of aortic dissection by attenuation of neutrophil migration
○Masumi Iketani1, Toshiyuki Aokage1,2, Mitsuhiro Kawata1,3, Ikuroh Ohsawa1 (1. Biol. Process Aging, TMIG, 2. Emerg. Med., TMIG, 3. CardioVasc. Surg., TMIG)
[2P-731]Adipose-specific Mipep knockout mice show tolerance to LPS-induced acute inflammation.
○Kota Nagasawa Nagasawa1, Yuka Nozaki1, Yuhei Mizunoe1, Masaki Kobayashi2, Yoshikazu Higami1,3 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Faculty of Core Research Natural Sciences Division, Ochanomizu University, 3. Research Institute for Biomedical Sciences, Tokyo University of Science)
[2P-732]DMRTA1 controls early T cell activation in naïve and memory T cells
○Hiroyuki Kondo1, Kunihiro Otsuka1, Kouji Yasutomo1 (1. Tokushima university)
[2P-733]The role of small G protein Arf1 in the innate immune responses
○Mami Sumiyoshi1, Daiki Iijima1, Tomoki Ito2, Toshio Watanabe3,4, Satoshi Matsuda1 (1. Dept. of Cell Signaling, Inst. of Biomed. Sci., Kansai Med. Univ., 2. Dept. of1st IntMed., Kansai Med. Univ., 3. Dept. of Synth. Sci., Grad.Sch.of Hum & Sci., Nara Women's Univ., 4. Dept. of Chem. Bio. Environ Sci., Inst of Nara Women's Univ.)
[2P-734]PRRX1 upregulates PD-L1 in human mesenchymal stem cells
○Taro Osawa1, Daisuke Yamada1, Tomoka Takao1, Lu Ming1, Takeshi Takarada1 (1. Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,)
[2P-735]The effect of psychological stress induced by social isolation on Crohn's disease relapse.
○Miu Ihara1, Shuya Ohira2,3, Yuki Yokoi1,2,4, Shota Takemi1,2,4, Yuna Abe4, Kanta Harasawa4, Ryo Matsushita1, Kiminori Nakamura1,2,4 (1. Innate Immunity Lab., Grad. Sch. of Life Sci., Hokkaido Univ., 2. Innate Immunity Lab., Faculty of Adv. Life Sci., Hokkaido Univ., 3. CRIS., Hokkaido Univ., 4. Innate Immunity Lab., Sch. of Sci., Hokkaido Univ.)
[2P-736]Transcriptome analysis of long non-coding RNAs in Mycobacterium avium complex–infected macrophages
○Harukazu Suzuki1, Mitsunori Yoshida2, Andrew Tau Jun Kwon1, Xian-Yang Qin1, Hajime Nishimura1, Shiori Maeda1, Yuji Miyamoto2, Yasuhiro Yoshida3, Yoshihiko Hoshino2 (1. RIKEN Center for Integrated Medical Sciences, 2. National Institute of Infectious Diseases, 3. University of Occupational and Environmental Health)
[2P-737]Roles of T cells with the expression of low levels of Bach2 accumulated in the lesional skin in the development and maintenance of allergic dermatitis
○Miyuki Omori-Miyake1, Masakatsu Yamashita1 (1. Dept. of Immunology and of Infections and Host Defenses, Ehime University Graduate School of Medicine)
[2P-738]Non-autonomous suppression of innate immune response in Drosophila sterile inflammation
○Yutaka Yoshida1, Soshiro Kashio1, Masayuki Miura1 (1. Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo)
[2P-739]Epithelial barrier dysfunction by intestine-specific AP-1B deficiency causes renal IgA deposition
○Yusuke Kinashi1, Keisuke Tanaka1, Shunsuke Kimura1, Daisuke Takahashi1, Hiroshi Ohno2, Koji Hase1 (1. Keio Univ., 2. RIKEN)
[2P-740]Detection of the mechanism of anti-tumor immune gene expression shown by cGAS/STING/RIG-I high-expressing cancer cells
○Kunihiro Miyazaki1, Ken Okuda1, Syunji Haruna1, Tateno Kohei1, Ryuta Suzuki1, Yuki Uchihara1, Atsushi Shibata1 (1. Div of Mol Oncol Pharm, Facul of Pharm, Keio University)
[2P-741]The Role of Histone Demethylase UTX in Regulation of T-Cell Differentiation in Inflammatory Bowel Disease
○Masayuki Iwasaki1, Nobuhito Muramoto1,2, Yasuyuki Sera1, Miho Koizumi1, Hiroaki Honda1 (1. Institute of Laboratory animals, Field of Human Desease Models, Major in Advanced Life Sciences and Medicine, Tokyo Women’s Medical University, 2. Department of Urology, Juntendo University)
[2P-742]Comprehensive Profiling of the Immune Landscape in Multiple Myeloma Using Advanced Bioinformatics Tools
○Shangru Jia1, Alok Sharma2,3,4, Artem Lysenko2,3, Keith Boroevich3, Tatsuhiko Tsunoda1,2,3 (1. Tsunoda Lab, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo., 2. Laboratory for Medical Science Mathematics, Department of Biological Sciences,School of Science, The University of Tokyo, Japan, 3. Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Japan, 4. Institute for Integrated and Intelligent Systems, Griffith University, Nathan, Brisbane, QLD4111, Australia)
[2P-743]Analysis of IgA nephropathy pathogenesis using conditional knockout mice of galactosyltransferase gene.
○Satoko Baba1,2, Chie Naruse2, Tomoko Matsuzaki2, Xuchi Pan2, Masahide Asano2 (1. Graduate School of Biostudies, Kyoto University , 2. Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University)
[2P-744]Development of a Novel Endotoxin Testing Method Using Human Monocyte-like Cell Line
○Moeri Okada1, Hiroki Koyama1, Kouichi Kurose1 (1. Food Sci. and Tech., TUMSAT.)
[2P-745]Regulatory Mechanism of Age-Related Changes in Allergic Responses
○Nanako Hioki1, Mitsuki Amaya1, Yuka Nagata1, Atsushi Furukawa1, Ryo Suzuki1 (1. Fac. Pharm. Sci., Kanazawa Univ.)
[2P-746]Identification and characterization of novel NF-κB inhibitors.
○Yoshiho Akiyama1, Masatoshi Takeiri1, Arai Keiko1, Yoshihide Kimura1 (1. IVY Cosmetics Corporation)
[2P-747]Mechanism and physiological significance of mechanical stress response in Kupffer cells.
○Hirofumi Sato1, Toshiyuki Irie1, Shota Toyoshima1, Daisuke Hishikawa1, hnin saungzarchi1, Mao Fujioka1, Mashito Sakai1 (1. Nippon Medical School, Department of Molecular and Medical Genetics.)
[2P-748]Utilization of mealworms as a Food Resource and Their Allergenicity
○Shumma AOKI1, Hiroki KOYAMA1, Kouichi KUROSE1 (1. Food Sci. and Tech., TUMSAT)
[2P-749]Exploratory research on plant-derived functional components that regulate γδ T cell function
○Ayuto Ishibashi1, Takumi Iwasawa1, Kazunori Kato1 (1. Toyo University)
[2P-750]Clonal landscape of autoantibody production in severe COVID-19
○Shuhei Sakakibara1,2, Yu-Chen Liu1, Masakazu Ishikawa1,3, Ryuya Edahiro1,4,5, Yuya Shirai1,4,5, Xu Zichang1, Songling Li1,6, Yuta Yamaguchi1,4, Teruaki Murakami1,4, Takayoshi Morita1,4, Yasuhiro Kato1,4, Haruhiko Hirata4, Yoshito Takeda4, Fuminori Sugihara1, Daisuke Motooka6, James B Wing1,7, Hisatake Matsumoto3,8, Hiroshi Ogura8, Atsushi Kumanogoh1,3,4,7,9, Yukinari Okada1,3,5,7,9,10,11, Daron M Standley1,3,6,7, Hitoshi Kikutani1, Daisuke Okuzaki1,3,6,7 (1. Immunology Frontier Research Center, Osaka Univ., 2. Jikei University of Health Care Sciences, 3. Center for Infectious Disease Education and Research, Osaka Univ., 4. Dept. of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka Univ. , 5. Dept. of Statistical Genetics, Graduate School of Medicine, Osaka Univ. , 6. Research Institute for Microbial Diseases, Osaka Univ., 7. Center for Advanced Modalities and DDS, Osaka Univ., 8. Dept. of Traumatology and Acute Critical Medicine, Graduate School of Medicine, Osaka Univ. , 9. Integrated Frontier Research for Medical Science Division, Osaka Univ., 10. Dept. of Genome Informatics, Graduate School of Medicine, The Univ. of Tokyo , 11. Riken Center for Integrated Medical Sciences)
[2P-751]The role of neutrophil extracellular traps in the formation of the breast cancer pre-metastatic niche.
○Taiko Kawakami1, Yusuke Nakanishi1, Kyoko Takahashi1 (1. Nihon Univ.)
[2P-752]Deficiency of Cathepsin A aggravates joint inflammation in rheumatoid arthritis
○Ji Yeong Park1, Zae Young Ryoo1 (1. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea)
[2P-753]Production of monoclonal antibody against derrisisoflavone A, bioactive compound from Derris scandens (Roxb.) Benth.
○Pitragorn Srimongkon1, Worapol Sae-Foo2, Supaluk Krittanai3, Gorawit Yusakul4, Waraporn Putalun1 (1. Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kean, Thailand, 2. Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, Thailand, 3. School of Preclinic, Institute of Science, Suranaree University of Technology, Nakhon-Ratchasima, Thailand, 4. School of Pharmacy, Walailak University, Nakhon Si Thammarat, Thailand)
[2P-754]Cathepsin A deficiency aggravates lipopolysaccharides-induced liver injury
○HeeYoung Chae1, Zae Young Ryoo1 (1. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea)
[2P-755]Elucidation of the mechanism of amphotericin B enhancing activity of nectriatides using Raman microspectroscopy
○Ryosuke Miyake1, Masahiro Ando2,3, Keisuke Kobayashi4, Hiroshi Tomoda4, Taichi Ohshiro4, Haruko Takeyama1,2,3,5 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. Res. Org. Nano Life Innov., Waseda Univ., 3. CBBD-OIL, AIST-Waseda Univ., 4. Grad. Sch. Pharm. Sci., Kitasato Univ., 5. Inst. Adv. Res. Biosyst. Dyn., Waseda Res. Inst. Sci. Eng., Waseda Univ.)
[2P-756]Functional analysis of host factors that regulate PAMP detection by pattern recognition receptors
○Yutaro Miura1, Yuga Sato2, Kazuhisa Murai3, Masao Honda3,4 (1. Department of Clinical Laboratory Medicine, School of Health Science, College of Medical, Pharmaceutical and Health Science, Kanazawa University, Japan, 2. Department of Clinical Laboratory Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, 3. Department of Health Sciences, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, 4. Department of Gastroenterology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan)
[2P-757]A report on the pathogenesis of diseases of Axolotl, Ambystoma mexicanum and their optimal medical-care.
○Santako Fuzzy-navel1, Haruka Axolotl Sugiyama1, Kazuaki Hagiwara1, Ya!min Edamame1, Yu Asumi1 (1. HAL lab)
[2P-758]A potential marker subset of blood-circulating cytokines in hematopoietic stem/progenitor cell differentiation to Th1 helper T cells in COVID-19
○Yasuo Takashima1, Tohru Inaba2, Tasuku Matsuyama3, Kengo Yoshii4, Masami Tanaka1, Kazumichi Matsumoto5, Kazuki Sudo6, Yuichi Tokuda1, Natsue Omi1, Masakazu Nakano1, Takaaki Nakaya7, Naohisa Fujita8, Chie Sotozono9, Teiji Sawa6,10, Kei Tashiro1, Bon Ohta3 (1. Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan, 2. Department of Infection Control and Laboratory Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan, 3. Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan, 4. Department of Mathematics and Statistics in Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan, 5. Faculty of Clinical Laboratory, University Hospital Kyoto Prefectural University of Medicine, Kyoto, Japan, 6. Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 7. Department of Infectious Diseases, Kyoto Prefectural University of Medicine, Kyoto, Japan, 8. Kyoto Prefectural Institute of Public Health and Environment, Kyoto, Japan, 9. Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 10. University Hospital Kyoto Prefectural University of Medicine, Kyoto, Japan)
[2P-759]Estimation of COVID-19 vaccine-induced antibody dynamics from 1 or 2 blood draws using the integrated approach of mathematical models and machine learning
○Daiki Tatematsu1, Shingo Iwami1 (1. Nagoya Univ.)
[2P-760]The host anti-viral factor PLSCR1 interacts with SARS-CoV-2 spike protein
○Shuichi Kusano1 (1. Kagoshima University)
[2P-761]Characterization of aptamers specific for tick-borne encephalitis virus particles and their application to in vivo imaging
○Yuji Fujii1,2, Minato Hirano1, Mizuki Fukuta1, Kentaro Yoshii1 (1. Department of Viral Ecology, CCPID, Nagasaki Univ., 2. Experimental Animal Research Division, CCPID, Nagasaki Univ.)
[2P-762]Comparison of subcellular localization of DAg proteins of kolmioviruses
○Akari Sono1, Masayuki Horie1,2,3, Mai Kishimoto1,2,3 (1. School of Veterinary Science, College of Life, Environment, and Advanced Science, Osaka Prefecture University, 2. Graduate School of Veterinary Science, Osaka Metropolitan University, 3. Osaka International Infectious Diseases Research Center, Osaka Metropolitan University)
[2P-763]Role of Host Hsp70 Isoform in SFTSV-Mediated Signal Transduction in Innate Immunity
○Shuhei Taguwa Taguwa1,2, Zecheng Jin1,2, Juan Vicente Bou Prados1,2, Kentaro Uemura1, Junki Hirano1, Kazuma Okada1, Chikako Ono1, Yoshiharu Matsuura1,2 (1. CiDER, Osaka Univ., 2. CAMaD, Osaka Univ.)
[2P-764]Elucidation of the pathogenic mechanism(s) of SARS-CoV-2 infection by using aged C57BL/6J mice
○Hiroshi Ueki1,2,3, Maki Kiso1, Yoshihiro Kawaoka1,2,3,4 (1. Institute of Medical Science, The University of Tokyo, 2. UTOPIA, University of Tokyo, 3. Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute,, 4. University of Wisconsin-Madison)
[2P-765]Novel EBV classification for disease risk prediction by large-scale variant analysis
○Taisei Fukushima1, Shun Ohki1, Rin Yoshizato2, Tomoharu Yasuda1 (1. Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 2. Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University)
[2P-766]Disturbance of miRNA biogenesis by nucleocapsid protein of Crimean-Congo hemorrhagic fever virus
○Minato Hirano1, Masami Shiimori2, Hirotaka Takahashi3, Kentaro Yoshii1 (1. CCPID, Nagasaki Univ., 2. Biomedical Science, NAIST, 3. PROS, Ehime Univ.)
[2P-767]Transcriptomic analysis to unveil gene expression patterns involved in high-yield and high-quality AAV production using human amniotic epithelial cell library
○Rena Moromizato1,2, Ryo Asahina1,2, Kazuaki Nakamura2,3, Takayuki Horiuchi1,2, Yugo Hirai1,2 (1. Chitose Laboratory Corp., 2. Manufacturing Technology Association of Biologics, 3. Department of Pharmacology, National Research Institute for Child Health and Development)
[2P-768(2PS-08-05)]Functional analysis of endogenous viral elements in Aedes aegypti mosquitoes naturally infected with an insect-specific virus
○Yasutsugu Suzuki1, Artem Baidaliuk2, Yuu Sekii1, Irish Coleen A. Asin1, Etienne Simon-Loriere2, Kozo Watanabe1 (1. Center for Marine Environmental Studies,Ehime University, 2. G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur)
[2P-769]Generation of rat monoclonal antibodies against HBV preS1
○Ayumi Kurisu1, Hironori Nishituji2, Chikako Yokoyama1, Taro Tachibana1 (1. Osaka Metro. Univ., 2. Fujita Health Univ.)
[2P-770]Identification of LGALS3/Galectin-3 as a novel positive regulator of Coxsackievirus B3 replication by a loss-of-function screening using the CRISPR-Cas9 system
○Azuki Yasuoka1, Mao Nishikawa1, Yuika Metsugi1, Kazuki Kaneko1, Hitomi Saiki1, Hikaru Shigenaka1, Mayuko Yagi1, Kosuke Yusa2, Jun Komano1 (1. Department of Microbiology and Infection Control, Osaka Medical and Pharmaceutical Univ., 2. LiMe, Kyoto Univ.)
[2P-771]Characterization of antigenic variation in rabies virus glycoprotein among street strains in the Americas
○Cassia Sousa Moraes1, Gabriel Gonzalez2, Kojiro Tabata1, Shinji Saito1, Hirofumi Sawa1, Yukari Itakura1 (1. Division of Biological Response Analysis, Institute for Vaccine Research and Development, Hokkaido University, Japan., 2. Division of Research Support, Institute for Vaccine Research and Development, Hokkaido University, Japan.)
[2P-772]Exploring key viral determinants of chikungunya virus pathogenicity
○Fumiyo Ogawa1,2, Rie Doi1,2, Shinya Okamura1,2, Takeshi Sugimoto1,2, Kotaro Ishida1,2, Naoya Shiraishi1,2, Kaoru Yamano1,2, Akino Emi3, Youichi Suzuki3, Takashi Nakano3, Hirotaka Ebina1,2 (1. Virus Vaccine group, BIKEN Innovative Vaccine Research Alliance Laboratories, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, 2. The Research Foundation for Microbial Diseases of Osaka University, 3. Department of Microbiology and Infection Control, Faculty of Medicine, Osaka Medical and Pharmaceutical Universit)
[2P-773]Function analysis of glycogen synthase PgcA of Chlamydia pneumoniae
○Takuma Otani1, Yoshinao Azuma1 (1. Kindai university)
[2P-774]Assembly of the segmented influenza A virus genome in viral inclusions
○Naoki Takizawa1 (1. Institute of Microbial Chemistry)
[2P-775]Discovery of SARS-CoV-2 replication inhibitors through screening of food-derived natural product library
○Midori TAKEDA1, Natsue MAEZONO1, Rina UCHIKOSHI1, Nobuyuki KATO1, Masanori IKEDA1 (1. Kagoshima University)
[2P-776]Characterization of the biological activity of the newly described enterotoxin-like toxins SEl26 and SEl27
○Hisaya Ono1, Yasunori Suzuki2, Dong-Liang Hu1 (1. Lab. of Zoonoses, Kitasato University, 2. Lab. of Hygiene, Kitasato University)
[2P-777]Syndecan-1 promotes infection of murine leukemia virus by interacting with virus particles on the cell surface
○Hidekazu Inoue1, Atushi Tanaka2, Sayaka Takase1,3 (1. Department of Biosciences, Graduate School of Science and Engineering, Soka University, 2. Research & Development Center, Osaka Medical and Pharmaceutical University, 3. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[2P-778]Mathematical Modeling of Lesion Pattern Formation in Dendritic Keratitis
○Mari Masunaga1, Reo Shimatani2, Kazumi Shinozaki3, Tomohiro Iida3, Takashi Miura1 (1. Kyushu University Graduate School of Medical Sciences, 2. Kyushu University School of Medicine, 3. Tokyo Women's Medical University Graduate School of Medical Science)
[2P-779]Detection of Hantavirus and Henipavirus in Shrews in Japan
○Fuka Kikuchi1,2, Karen Yamada2,3, Ken Maeda4, Ai Hayashi1,5, Kumiko Yoshimatsu6, Tetsuya Mizutani2, Motoi Suzuki1,5, Richard Yanagihara7, Satoru Arai1 (1. CSIER, NIID, 2. CEPiR, Tokyo Univ. of Agr. and Tec., 3. Fac. of Sci. , Tokyo Univ. of Sci., 4. Dept. Vet. Sci. , NIID, 5. Grad. Sch. of Med. , Tohoku Univ., 6. IGM, Hokkaido Univ., 7. John A. Burns Sch. of Med. , Univ. of Hawaii)
[2P-780]Genetically distinct hantaviruses in two bat species in Panamá
○Karen Yamada1,2, Fuka Kikuchi1,3, Jonathan L Dunnum4, Pablo Gutiérrez Moreno5, Publio González D5, Blas Armién5,6, Mihail Pérez-Callejas5, Danielle Land4, Jocelyn Colella7, Tetsuya Mizutani3, Ken Maeda8, Motoi Suzuki1, Stephen Greiman9, Carlos Alberto Carrión-Bonilla4, Joseph A. Cook4, Richard Yanagihara10, Satoru Arai1 (1. CSIER, NIID, 2. Fac. of Sci. , Tokyo Univ. of Sci., 3. CEPiR, Tokyo Univ. of Agr. and Tec., 4. Mus. of SW Biol. and Dept. of Biol. , Univ. of New Mexico, 5. GMI, 6. SENACYT, 7. EEB, Univ. of Kansas, 8. Dept. Vet. Sci. , NIID, 9. Dept. of Biol, Georgia Southern Univ, 10. John A. Burns Sch. of Med. , Univ. of Hawaii)
[2P-781]Identification of antibody-escape mutations using only MERS-CoV spike in virus-free cultured human cells.
○Jiei Sasaki1, Satoshi Ikegame2, Hiroyuki Yoshitomi3, Hideki Ueno3, Takao Hashiguchi1 (1. LAB. OF MEDICAL VIROLOGY, Institute for Life and Medical Sciences, Kyoto University, 2. Dept of Respiratory Medicine, Grad Sch of Medical Sciences, Kyushu Univ, 3. Dept of Immunology, Grad Sch of Med, kyoto univ)
[2P-782]Elucidation of regulatory mechanisms of splicing of murine leukemia virus
○Kana Onuma1, Narumi Oshida1, Xueyang Zhu1, Sayaka Takase-Yoden1,2 (1. Graduate School of Science and Engineering, Soka University, 2. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[2P-783]Possible involvement of BAF in base excision repair
○Haruka Kikuchi1, Yuna Sugiyama1, Yuki Matsuo1, Yuu Onoda1, Ayumi Chikamatsu1, Namiko Noma1, Taro Mannen1, Shinji Ito2, Ryotaro Nishi3, Toshiya Hayano1 (1. Ritsumeikan Univ., 2. Kyoto Univ., 3. Tokyo Univ. of Tech.)
[2P-784]Possible involvement of BAF in nucleotide excision repair
○Kota Kamei1, Yuki Matsuo1, Hiroki Iwamoto1, Karin Watanabe1, Namiko Noma1, Taro Mannen1, Shinji Ito3, Ryotaro Nishi2, Toshiya Hayano1 (1. Ritsumeikan Univ. Col. of Life Sci., 2. Tokyo Univ. of Tech. Col. of Biosci and Biotech, 3. Kyoto Univ. Grad. Sch. of Med)
[2P-785]Possible involvement of BAF in repair of DNA double-strand break
○Yuki Matsuo1, Tetsu Hirai1, Yuu Onoda1, Hiroki Iwamoto1, Masahito Shimamoto1, Namiko Noma1, Taro Mannen1, Shinji Ito3, Ryotaro Nishi2, Toshiya Hayano1 (1. Ritsumeikan Univ. Col. of Life Sci., 2. Tokyo Univ. of Tech., 3. Kyoto Univ. Grad. Sch. of Med)
[2P-786]Mitochondrial respiratory chain dysfunction and muscle pathology in mouse model of premature aging.
○Hiroaki Tamashiro1, Kaori Ishikawa2, Kazuto Nakada2 (1. Grad. Sch. of Sci. and Tech., Univ. of Tsukuba , 2. Inst. of Life and Env. Sci., Univ. of Tsukuba)
[2P-787(2PS-13-06)]Germ cell suppresses aging via vitamin D
○Tomomi Niwa1,2, Hikaru Ino1,2, Kota Abe1, Tohru Ishitani1,2 (1. Department of Homeostatic Regulation, Division of Cellular and Molecular Biology. Research Institute for Microbial Diseases, Osaka University, 2. Department of biological sciences, Graduate school of science, Osaka Univ.)
[2P-788]Myo-inositol can activate the CKK-1/CMK-1/UNC-43/DAF-16 pathway via the ITR-1/Ca2+ signaling, producing longevity effects in Caenorhabditis elegans
○Nae-Cherng Yang1, Chia-Yu Chin1 (1. Chung Shan Medical University)
[2P-789]Molecular mechanisms underlying the age-related decline in cardiac mitochondrial biogenesis
○Tsuyoshi Kadomatsu1, Michio Sato1, Yuichi Oike1 (1. Kumamoto University)
[2P-790]Upregulated expression of lamin B receptor increases cell proliferation and suppresses genomic instability: implications for cellular immortalization
○Yoshimi Yamakami1, Atsuki En1, Kentaro Takemoto1, Kazuhiko Nakabayashi2, Michihiko Fujii1 (1. Yokohama City University, 2. National Center for Child Health and Development)
[2P-791]Comparison of the Efficiency of Orthologous Proteins in Mammalian HR Repair and Their Effects on Genome Stability and Longevity.
○Ruifeng Shen1, Yutaro Hori2, Takehiko Kobayashi1,2 (1. Biological Science, Tokyo Univ., 2. IQB, Tokyo Univ.)
[2P-792]Activation of skin-mediated organ interaction and its molecular basis
○Ryoma Sendo1, Shunta Shirasaka1, Yoshinori Katakura1 (1. Kyushu University)
[2P-793]Investigation of cell senescence associated gene by CAGE method in human normal fibroblast TIG-1.
○Yusuke Imaizumi1, Kousuke Tashiro2, Yoshinori Katakura2, Kenji Kishihara3, Tsukasa Fujiki3 (1. Dept. of Pharm. Sci. Nagasaki Int. Univ., 2. Gra. Sch. of Agr. Kyusyu Univ., 3. Gra. Sch. of Pharm. Sci. Nagasaki Int. Univ.)
[2P-794]The crosstalk between NK cells and senescent fibroblasts
○Xintong ZHENG1, Teh-Wei WANG1, Makoto NAKANISHI1 (1. The University of Tokyo)
[2P-795(2AS-07-02)]Regulation of organelle dynamics with detyrosination: Implications for aging
○Miho Kobayashi1,2,3, Honoka Hirose1, Yasuhiro Suzuki2,4, Masanori Nakayama3,5, Yasufumi Sato2,4, Tetsuro Watabe1 (1. Dept. of Biochem., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ (TMDU)., 2. Dept. of Vasc. Biol., IDAC., Tohoku Univ., 3. Lab. for Cell Polar. and Organ., MPI for Heart and Lung Res., 4. NICHe., Tohoku Univ., 5. Org. for Res. Strat. and Dev., Okayama Univ.)
[2P-796]Effects of electroacupuncture stimulation on skeletal muscle of senescence-accelerated mouse
○Mika Ohta1,2, Takao Inoue3, Aki Sugano2,4, Arato Okuno5, Yoshiaki Someya6, Akihiko Ito3, Yutaka Takaoka1,2,6 (1. Department of Computational Drug Design and Mathematical Medicine, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, 2. Department of Medical Systems, Kobe University Graduate School of Medicine, 3. Department of Pathology, Faculty of Medicine, Kindai University, 4. Center for Clinical and Translational Research, Toyama University Hospital, 5. Department of Health and Nutrition, Faculty of Human Design, Shibata Gakuen University, 6. Center for Data Science and artificial intelligence research promotion, Toyama University Hospital)
[2P-797]Evaluation of ovarian aging in Drosophila using Raman spectroscopy and the exploration of anti-aging natural compounds
○Chisaki Kisoda1, Kazutaka Akagi2, Akinori Taketani3, Keiichi Koizumi2 (1. Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2. Inst. of Nat. Med., Univ. of Toyama, 3. RCPDS, Univ. of Toyama)
[2P-798(2PS-13-05)]Inhibition of Neuronal Senescence by DHA: Elucidation of a Novel Mechanism Mediated by SARM1
Natsuki Tanaka1, Ryoto Hamamoto1, Ikuko Yao1, ○Michinori Toriyama1 (1. Kwansei Gakuin University)
[2P-799]WDR6 gene deletion regulates Fatty acid oxidation to suppress fat accumulation in Leptin ob/ob Mouse model of obesity
○Jinyun Wang1, Issa Furihata1, Tatsunobu Nakagawa1, Akihito Ishigami2, Yoshitaka Kondo2, Toshimitsu Komatsu3, Isao Shimokawa3, Takuya Chiba1 (1. Biomed. Gerontol. Lab., Faculty of Human Sci., Waseda Univ., 2. Mol. Reg. of Aging, TMIG, 3. Grad. Sch. Biomed. Sci., Nagasaki Univ.)
[2P-800]Functional analysis of epidermal fatty acid-binding protein in aging-related changes in skin tissue
○Makoto Nose1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology・Graduate School of Science and Technology・Master's Program of Applied Biology)
[2P-801]Analyzing the effects of Chlorella sorokiniana on development and longevity in Drosophila melanogaster
○Yuga Takahashi1, Kazutaka Akagi2, Ayaka Nakajima3, Hirobumi Tada4, Keiichi Koizumi2 (1. Dept. of Pharma. Sci., Univ. of Toyama, 2. Inst. of Nat. Med., Univ. of Toyama, 3. Euglena Co.,Ltd., 4. Dept. of Nutrition., Univ. of Shigakkan)
[2P-802]Identification and Functional Analysis of Rejuvenation Factors that Reverse Irreversible Cellular Senescence
○Naoaki Abe1,2, Rebekah Gah-Hei WEI1, Teh-Wei Wang1, Satoshi Kawakami1, Makoto Nakanishi1 (1. Div.of Cancer Cell Biol., Inst. of Med. Sci.,Univ.of Tokyo, 2. Dept. of Mole.Biol., Grad.Sch.of Med.,Univ. of Tokyo)
[2P-803]Global Changes in Open Reading Frame Dominance with Aging in Intestinal Organoids
○Yohko Yamaguchi1, Kina Matsumoto1, Akiko Endo2, Noriyuki Suzuki1, Kazuto Kugou3, Yoshinori Hasegawa3, Yoshitaka Hippo2, Yusuke Suenaga2 (1. Toho University, 2. Chiba Cancer Center Research Institute, 3. Kazusa DNA Research Institute)
[2P-804]Depletion of Pdia6 exacerbates ferroptosisvia SLC7A11/STAT3 pathway in mouse hippocampus
○Hyejin Hyung1, Zae Young Ryoo1 (1. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University)
[2P-805]Development and Evaluation of a Green Extraction Method for Flavonoids from the Fruit of Oroxylum indicum Using Natural Deep Eutectic Solvents (NADES)
○Chonticha Srimawong1, Waraporn Putalun1 (1. Department of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen, Thailand)
[2P-806]The effect of Mitochondrial Ubiquitin Ligase decrease on repair after oxidative stress in skin
○Midori Tanaka1, Yuki Inokuchi1, Shiro Makihara1, Akihisa Morito1 (1. Taisho Pharmaceutical Co., Ltd.)
[2P-807]Development of an in vitro senescence model for apical cell extrusion studies
○Rachelle Anne So Dante1, Yasumasa Bessho1, Takaaki Matsui1 (1. Gene Regulation Research, Graduate School of Science and Technology, Nara Institute of Science and Technology)
[2P-808]Identification and Functional Significance of Acetylated Proteins in Sarcopenic Muscle
○Ryusuke Hosoda1, Ryuta Nakashima1, Naotoshi Iwahara2, Iyori Nojima1, Atsushi Kuno1 (1. Department of Pharmacology, Sapporo Medical University School of Medicine, 2. Department of Neurology, Sapporo Medical University School of Medicine)
[2P-809]Evaluation of the effect of FAM19A2 derived from follicular thyroid carcinoma on macrophage polarization.
○Yuto Imanishi1, Ryosuke Hashizume1, Ryotaro Miyamoto1, Ayano Shinozuka3, Motoki Hoshina3, Runa Matsumoto1, Kaho Kobayashi1, Tomoo Zikuzono2, Iwao Sugitani2, Takashi Inui1, Osamu Ishibashi1 (1. Grad. Sch. of Agri., Osaka Metro. Univ., 2. Dept. Endocr. Surg., Nippon Med. Sch. Hosp., 3. Diagnostics Division, YAMASA Corporation)
[2P-810]Verification of cancer malignancy caused by mitochondrial DNA mutations.
○Sakura Saito1, Kazuto Nakada2, Kaori Ishikawa2 (1. Degree Programs in Life and Earth Sciences, Graduate School of Science and Technology, University of Tsukuba., 2. Faculty of Life and Environmental Sciences, University of Tsukuba.)
[2P-811]Multi-omics analysis on adaptive mechanisms of aneuploidy formation in cancer cells
○Shicheng Zhang1, Tomoko Yamamori-Morita2, Ryo Kamata2, Kazuki Nakai2, Chiaki Mashima2, Hiroshi Haeno1, Akihiro Ohashi2 (1. Research Institute for Biomedical Sciences, Tokyo University of Science, 2. Exploratory Oncology Research & Clinical Trial Center, National Cancer Center)
[2P-812]Development of a detection probe for quiescent cancer cells using a reversible cell model
○Koki Kamijo1, Kotaro Miyamoto1, Shinae Kondoh1,2, Tetsuya Kadonosono1 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. National Institute of Technology, Nara college)
[2P-813]search of cancer stem cell regulators and their regulatory mechanisms using CRISPR-activation screening.
○Yuki Nishida1, Kazuharu Arakawa1, Osamu Nureki2, Tomoyoshi Soga1, Shojiro Kitajima1 (1. Keio University, 2. Tokyo University)
[2P-814]Tumor Protein D53 (TPD53) is involved in malignant transformation of low-malignant oral squamous cell carcinoma cells.
○Yoshiki Mukudai1, Masataka Watanabe1, Nodoka Kindaichi1, Maki Nara1, Konomi Yamada1, Yuzo Abe1, Asami Houri1, Toshikazu Shimane1, Tatsuo Shirota1 (1. Showa Univ.)
[2P-815]ELF4-mediated CDK6 expression promotes Cancer Stemness in Endometrial Cancer
○Wen-Wei Chang Chang1, Wen-Ling Wang1 (1. Chung Shan Medical University)
[2P-816]Hyaluronan-mediated intercellular communication between prostate stromal cells and cancer cells
○Ryo Saga1, Yoichiro Hosokawa1 (1. Hirosaki University)
[2P-817]The multiple roles of p63 in human parotid gland duct adenocarcinoma cells
○Masahiko Oyanagi1,2, Takumi Konno2, Akito Kakiuchi1, Terufumi Kubo3, Shin Kikuchi3, Soushi Nisida1, Masaya Nakano1, Kizuku Ohwada1, Kazufumi Obata1, Takuya Kakuki1, Makoto Kurose1, Yuki Ohsaki4, Takayuki Kohno2, Takashi Kojima2 (1. Department of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, 2. Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, 3. Department of Pathology (1), Sapporo Medical University, 4. Department of Anatomy (1), Sapporo Medical University)
[2P-818(2MS-08-06)]The CDC7 inhibitor-induced replication stress inflames the aneuploid cells to sensitize immune checkpoint inhibitors
○Akihiro Ohashi1,2 (1. National Cancer Center Japan, 2. Univ. Tokyo)
[2P-819]Par14 impacts the transcriptional activity of estrogen receptor by enhancing phosphorylation, and consequently, promoting the growth of breast cancer cells.
Masa-Ki Inoue1, Rena Ueda1, Mikako Nakanishi1, Tomoichiro Asano1, ○Yusuke Nakatsu1 (1. Hiroshima University)
[2P-820]Evaluation of Photoresponsive TGF-β Receptor (ALK-5) Inhibitors in breast cancer and glioblastoma cells
○Ryu Miyazaki1,2, Masumi Tsuda2,3, Jiajun Qi4,5, Nobuyuki Tamaoki4,5, Shinya Tanaka2,3 (1. School of Medicine 6th Grade, Hokkaido University, 2. Depertment of Cancer Pathology, Faculty of Medicine, Hokkaido University, 3. Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, 4. Research Institute for Electronic Science, Hokkaido University, 5. Graduate School of Life Science, Hokkaido University)
[2P-821]Formation and role of primary cilia in breast CAFs
○Miku Takeda1, Tetsuo Kobayashi1, Yoshihiro Mezawa1, Manami Tominaga1, Mariko Hirano1, Saki Hasegawa1, Honoka Komukai1, Hiroko Onagi2, Ritsuko Sasaki3, Goro Kutomi3, Akira Orimo1 (1. Juntendo Univ., Sch. of Med., Dep. of Path. and Onc., 2. Juntendo Univ., Sch. of Med., Dep. of Hum. Path., 3. Juntendo Univ., Sch. of Med., Dep. of Brea. Onc.)
[2P-822]KDM2B, a histone demethylase, is essential for cell-cell communication in leukemic stem and differentiated cells via WNT10b/β-catenin signaling in a paracrine manner
○Yuichiro Nakata1, Ichiro Manabe1, Hiroaki Honda2 (1. Graduate School of Medicine, Chiba University, 2. Institute of Laboratory Animals, Tokyo Women’s Medical University)
[2P-823]Effects of EMT-Induced Pancreatic Cancer Cell-Derived Extracellular Vesicles on Metabolites and Cellular Environment
○Haruna Aiba1,2, Hayasaka Ryosuke1, Masako Hasebe1, Momo Sato1,3, Yukako Suzuki1,3, Tomoyoshi Soga1,2,3, Akiyoshi Hirayama1,2,3 (1. Inst. Adv. Bio. sci., Keio Univ., 2. Dept. Environ. Info. Stud., Keio Univ. , 3. Syst. Biol. Program, Grad. Sch. Media Gov., Keio Univ.)
[2P-824]Real-time tracking of tumor growth and metastasis in syngeneic model
○Asako Sakaue-Sawano1, Akihisa Takahashi2, Atsushi Miyawaki1 (1. RIKEN, 2. Gunma University)
[2P-825]Bidirectional action of 17-β-estradiol on endometrial cancer cells with different degrees of differentiatio
○Natsumi Hamasaki1, Eisaburo Sueoka1, Takahiro Yaguchi2 (1. Department of Laboratory Medicine, Saga University , 2. Department of Medical Laboratory Science, Graduate School Health and Welfare Sciences, International University of Health and Welfare)
[2P-826]RelB suppresses deregulated E2F activity
○Syogo Fujio1, Kiyoshi Ootani1 (1. Kwansei Gakuin University)
[2P-827]Intracellular Dynamics of Extrachromosomal DNA in Cancer Cells
○Yohei Sugimoto1, Seiko Yoshino1, Hiroshi I Suzuki1 (1. Nagoya Univ. Grad. Sch. Med. Div. Mol. Oncol.)
[2P-828]Comprehensive understanding of BCR-ABL interactome in CML using proximity-dependent biotin labeling
○Takanori Nakamura1, Yosei Yamauchi1, Hidetaka Kosako2, Mikihiko Naito1,3, Junya Masumoto1, Tatsuya Sawasaki1 (1. PROS, Ehime Univ., 2. Fujii Memo. Inst. Med. Sci., Inst. of Adv. Med.Sci., Tokushima Univ., 3. Grad. Sch. of Pharm., The Univ. of Tokyo)
[2P-829]Integrated network analysis of acute myeloid leukemia
○Ryo Ogawa1,2, Satoshi Ohno1, Tomoya Sakuma1,2, Takumi Ito1,3, Kohei Ota1,2, Hideyuki Shimizu1,2 (1. Dept. AI Systems Medicine, DSC, Tokyo Med. Dent. Univ., 2. Grad. Sch., Med. Dent. Sci., Tokyo Med. Dent. Univ., 3. Sch. Med., Tokyo Med. Dent. Univ.)
[2P-830]Synthesis of natural product analogs showing inhibitory effect on T-cell acute lymphoblastic leukemia
○Kensuke Yanada1, Tomoya Higashi1, Tomoki Hosoya1, Humiya Seki2, Takahiko Hara2, Nobuo Kitada1, Takashi Hirano1, Shojirou Maki1 (1. Department of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, 2. Stem Cell Project, Tokyo Metropolitan Institute of Medical Science)
[2P-831]Dynamic Analysis of Nucleolar Proteins in Cancer Cells Undergoing Nucleolar Stress Induction and Anticancer Drug Treatment via Monoclonal Antibodies
○Akiho Kawaguchi1, Yuki Nishino2, Taro Tachibana1,2, Chikako Yokoyama1,2 (1. Osaka City Univ., 2. Osaka Metro. Univ.)
[2P-832]Establishment of the cancer extravasation analysis by utilizing the yolk sac vasculature in early embryos and its applications.
○Mizuki Morita1, Ryo Fujii1, Asuka Ryuno1, Manami Morimoto1, Akihito Inoko2, Junichi Ikenouchi1, Yoshiki Hayashi1, Yuji Atsuta1, Takayuki Teramoto1, Daisuke Saito1 (1. Kyushu univ., 2. Aichi Medical Univ.)
[2P-833]Disruption of intracellular iron homeostasis induces cancer cell death
○Saho Yoshikawa1, Yoshiki Yamamoto2, Ayuna Hattori3, Ito Takahiro3, Masaki Miyazawa4 (1. Graduate School of Engineering, Course of Applied Science, Tokai Univ., 2. Department of Biosystems Science, Kyoto Univ., 3. Institute for Life and Medical Sciences, Kyoto Univ., 4. Department of Health Management, Tokai Univ.)
[2P-834]Identifying and targeting non-canonical function of histone demethylase LSD1 in therapeutic resistance in melanoma
○Anlun Xu1, Riyo Imamura2, Kunihiko Hinohara1, Hiroyoshi Nishikawa3, David E. Fisher4, Shinichiro Kato1 (1. Department of Immunology, Graduate School of Medicine, Nagoya University, 2. Drug Discovery Initiative (DDI), The University of Tokyo, 3. Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, 4. Center for Cancer Research/Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School)
[2P-835]N-terminal region of the transcription factor E2F1 contains a novel transactivation domain and recruits the general transcription factor GTF2H2
○Lin Zhao1, Kiyoshi Ohtani1 (1. Graduate School of Science and Technology,Kwansei Gakuin University)
[2P-836]Hepatoma Derived Growth Factor and Tumor Necrosis Factor-Alpha Signaling in Helicobacter pylori Infected Human Gastric Cancer Organoids
○Kenly Wuputra1,2,3, Chia-Chen Ku1,2,3, Ming-Ho Tsai1,2,3, Ya-Han Yang1,2,3, Deng-Chyang Wu2,4, Kazunari K Yokoyama1,2,3 (1. Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan., 2. Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan., 3. Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung, 80756, Taiwan., 4. Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, 80756, Taiwan.)
[2P-837]NCYM promotes cholangiocarcinogenesis via the induction of autophagy
○Daisuke Muto1,2, Kazuma Nakatani1,2, Hiriyuki Kogashi1,2, Zulfin Ummi1,2, Shino Okamoto2, Akiko Endo2, Harumi Saida2, Akane Sada2, Kazuto Kugo4, Yoshinori Hasegawa4, Yusuke Suenaga2, Yoshitaka Hippo1,2,3 (1. Grad. Sch. of Med. & Pharm. Sci., Chiba Univ., 2. Chiba cancer center reserch institute Laboratory of Evolutionary Oncology, 3. Lab. of Precision Tumor Model Systems, CCCRI, 4. Dept. of Applied Genomics, Kazusa DNA Res. Inst.)
[2P-838]Expression of tumor suppressor FHIT is regulated by LINC00173-SNAIL axis
○Satoshi Sakai1, Takahito Suzuki1, Tatsuya Ohhata1, Masatoshi Kitagawa1 (1. Department of Molecular Biology, Hamamatsu University School of Medicine)
[2P-839(2MS-08-05)]Deciphering the mechanism of cisplatin resistance acquisition in small cell lung cancer
○Takeshi Tsuruda1, Manabu Kodama1, Keiichi Nakayama1 (1. Lab. Anticancer Strategies, Advanced Res. Inst., Inst. Sci. Tokyo)
[2P-840]Investigations for recovering Wnt receptor degradation function to oncogenic RNF43 mutants
○Tadasuke Tsukiyama1 (1. Hokkaido Univ.)
[2P-841]Cancer cells acquire treatment resistance with compensatory autophagy
○Takahito Fukui1, Manami Yabumoto1, Misuzu Nishida1, Shiori Hirokawa2, Riho Sato3, Taichi Kurisu1, Miyu Nakai1, Md Abul Hassan4, Koji Kishimoto5 (1. Division of Bioscience and Bioindustry, Tokushima University Graduate school of Sciences and Technology for Innovation., 2. Graduate School of Environment and Energy Engineering, Waseda University., 3. Graduate School of Medical Life Science, Yokohama City University, 4. Faculty of Bioscience and Bioindustry, Tokushima University Graduate school of Advanced Technology and Science., 5. Division of Bioscience and Bioindustry, Tokushima University Graduate School of Technology, Industrial and Social Sciences)
[2P-842]Effect of a double-stranded RNA binding protein NF90 on the progression of NASH-HCC through the suppression of microRNA biogenesis
○Takuma Higuchi1, Rena Kishiue1, Keiko Morisawa1, Masayuki Tsuda2, Takeshi Suzuki3, Shuji Sakamoto1 (1. Lab. of Mol. Biol., Sci. Res. Cent., Kochi Univ., 2. The Div. of Animal Sci., Sci. Res. Cent., Kochi Univ., 3. Div. of Func. Genome, Cancer Res. Inst., Kanazawa Univ.)
[2P-843]Role of Polo like kinase in drug resistance of prostate cancer cell lines to proteasome inhibitors
○Miyu Uehara1, Katsumi Shigemura2, Kenichi Yoshino3, Itsuko Fukuda1, Yasuhito Shirai1, Shuji Ueda1 (1. Graduate School of Agicultural Science, Kobe University, 2. School of Medicine, Teikyo University, 3. Biosignal Center, Kobe University)
[2P-844]Analysis of the influence of mutated p53 gene on tumorigenesis in newts
○Tomoya Nakayoshi1,2, Mie Nakajima3, Honoka Umeyama3, Takashi Takeuchi3, Tetsushi Sakuma2,4,5, Takashi Yamamoto2,4, Kazuko Okamoto1,2, Toshinori Hayashi1,2 (1. Amphibian Research Center, Hiroshima University, 2. Graduate School of Integrated Sciences for Life, Hiroshima University, 3. Division of Developmental Biology, School of Life Sciences, Faculty of Medicine, Tottori University, 4. Genome Editing Innovation Center, Hiroshima University, 5. Graduate School of Agriculture, Kyoto University)
[2P-845]Exploring Multi-Low Dose Combination Strategies for Enhanced Therapeutic Efficacy in Triple-Negative Breast Cancer
○Yunhui Jeong1, Milad Ghomlaghi1,2, Tao Zhang1, Roger Daly1,2, Tony Tiganis1,2, Sung-Young Shin1, Lan K Nguyen1,2 (1. Biomedicine Discovery Institute, Cancer Program, Monash University, Clayton, Victoria 3800, Australia, 2. Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia)
[2P-846]Honokiol, a natural small compounds, anti- tumor effects on human leukemia cells
○Miki Takahashi1, Ota Masato1 (1. Div. of Human Dev., Grad. Sch. of Human Life Sci., Japan Women’s Univ.)
[2P-847]In vitro analysis of the effects of stellate cells derived from human iPS cells on normal pancreatic duct cells under the anticancer drug condition.
○KOKI KAMO1, Tatuya Kometani2, Taku Chibazakura1 (1. Dept. Biosci., Tokyo Univ. Agric., 2. Dept. Nutr. Sci. Food Safety, Tokyo Univ. Agric.)
[2P-848]Glioma cell ivasion and proliferation mechanism
○Kentarou Baba1, Ami Fukushi-Kumagaya1, Zhize Xiao2, Asako Katsuma3, Daisuke Kawauchi2, Yonehiro Kanemura3, Naoyuki Inagaki1 (1. Division of Biological Science, Nara Institute of Science and Technology, 2. Department of Neuro-Oncology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, 3. Division of Regenerative Medicine, Department of Biomedical Research and Innovation, Institute for Clinical Research, NHO Osaka National Hospital)
[2P-849]Molecular mechanisms by which metastatic prostate cancer cell PC3 acquires serum-independent proliferative and migratory potential in an IRS-2-dependent manner.
○Raku Nagano1, Haruka Furuta1, Yina Sheng1, Ayaka Takahashi1, Shini-Ichiro Takahashi1, Fumihiko Hakuno1 (1. The University of Tokyo Graduate School)
[2P-850]Elucidation of the effects of microenvironment on oncogenic transformation of benign human mammary tumors using single cell spatial analysis.
○Soto Okubo1, Satoi Nagasawa1, Yutaka Suzuki1 (1. Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo)
[2P-851]The usefulness of mitochondrial electron transport chain inhibitors in non-small cell lung cancer.
○Kanon Hirai1, Aya Shiba2, Ryutaro Sekimoto1, Daisuke Matsubara2 (1. University of Tsukuba, 2. University of Tsukuba institute of medicine)
[2P-852]Platelets adhere to CD8 positive T cells and inhibit antigen-specific tumor cell killing
○Sae Nishiguchi1,2, Masaru Yokomura1, Seiji Nagano3, Hiroshi Kawamoto3, Satoshi Takagi1, Ryohei Katayama1,2 (1. Div. Exp. Chemother., Cancer Chemother. Ctr., JFCR, 2. Dept. CBMS, Grad. Sch. Front. Sci., The Univ. of Tokyo, 3. Lab. Immunol., LiMe, Kyoto Univ.)
[2P-853]Development of Bispecific T-cell engager T-cell receptor mimic antibodies targeting Glypican-3
○Kosei Ozawa1, Masaharu Isobe2, Nobuyuki Kurosawa2 (1. Prog Phar Sci & Tech,Grad Sch Phar Medi Sci,univ Toyama, 2. Fact Eng,Acad Assy,Univ Toyama)
[2P-854]Development of photothermal agents for highly efficient induction of apoptosis dependent on near-infrared light.
○Kazunori Watanabe1, Mai Miyamoto1, Eiji Matsuura1, Takashi Ohtsuki1 (1. Okayama Univ.)
[2P-855]SFPQ inactivation induced cell death
○Karin Otsuka1, Hisashi Hisatomi1 (1. Seikei University)
[2P-856]Induction of necrosis in cancer cell lines by atmospheric pressure plasma irradiation
○Momoko Fukuda1, Hisashi Hisatomi1 (1. Seikei University)
[2P-857]Immune response evaluation in pancreatic cancer mouse models following proton beam irradiation and anti-PD-L1 immunotherapy
○Tuyen Thuy Bich Ho1, Alessandro Nasti1, Akihiro Seki2, Yoshio Sakai2, Kosuke Satomura3, Shingo Inagaki3, Norihiko Ogawa3, Masaki Miyazawa2, Hiroki Nomura3, Kyo Kume4, Munetoshi Maeda4, Hiroyasu Tamamura5, Makoto Sasaki5, Kazutaka Yamamoto5, Taro Yamashita2,3, Shuichi Kaneko1,2,3 (1. Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, 2. Department of Gastroenterology, Kanazawa University Hospital, 3. System biology, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, 4. Proton Medical Research Division, Research & Development Department, The Wakasa Wan Energy Research Center, 5. Proton Therapy Center, Fukui Prefectural Hospital)
[2P-858]Alternative splicing of fibulin 2 creates pro-metastatic extracellular matrix environment in colorectal cancer
○Ryo Funayama1,3, Wei-Chen Kao1, Yujue Wang1,4, Shingo Toyama5, Masaki Hosogane1, Masaki Matsumoto6, Keiichi I Nakayama3, Keiko Nakayama1,2 (1. Dept. of Cell Proliferation, ART, Grad. Sch. of Med., Tohoku Univ., 2. Ochanomizu Res. Fac., Biosci. Ctr., Inst. Sci. Tokyo, 3. Lab. Anticancer Strategies, Advanced Res. Inst., Inst. Sci. Tokyo, 4. Dept. of Medical Biochemistry, Grad. Sch. of Med., Tohoku Univ., 5. Dept. of Surgery, Grad. Sch. of Med., Tohoku Univ., 6. Dept.of Omics Sys. Biol., Grad. Sch. of Med. Dent. Sci., Niigata Univ.)
[2P-859]Targeting of cancer cells with GlcNAc polymers and their anti-cancer effects
○Karera Kitagawa1, Miura Yoshiko2, Kobayashi Shingo3, Ise Hirohiko3 (1. Applied Chemistry, Graduate School of Engineering, Kyushu University, 2. Chemical Engineering, Graduate School of Engineering, Kyushu University, 3. IMCE, Kyushu University)
[2P-860]Induction of additional anti-autophagic activity in Tamoxifen derivative through coupling of basic functional groups
○Yuta Semba1, Kyoka Komukai2, Eri Murata2, Fumi Satoh2, Takatsugu Murata2, Isamu Shiina2, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Dept. of Sci. Eng., Tokyo Denki Univ., 2. Dept. of Sci., Tokyo Univ. of Sci.)
[2P-861]The effects of novel retinoid derivative on a gefitinib-resistant cell line derived from human lung adenocarcinoma
○Makito Motoyama1, Runa Miyakawa2, Yoshitomo Suhara1,2, Ichiro Yajima1,2 (1. Department of Bioscience and Engineering, College of Systems Engineering and Sciences, Shibaura institute of Technology Graduate School of Engineering and Science, 2. Department of Bioscience and Engineering, Shibaura institute of Technology of Engineering and Science)
[2P-862]De novo protein synthesis capacity of tumor-educated platelets promotes hepatocarcinogenesis
○Hiroki Tanaka1, Kie Horioka2, Masanori Goto1, Yumiko Fujii1, Kumi Takasawa1, Masayo Kamikokura1, Akira Takasawa1 (1. Division of Tumor Pathology, Department of Pathology, Asahikawa Medical University, 2. Department of Forensic Medicine, Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu)
[2P-863]DNA methylation synthetic lethality of a paralog combination.
○EBATA TAKAHIRO1, HIDEYUKI TAKESHIMA1, YUMI FURUICHI1, YUI OHASHI1, RYOMA MASHIKO1, TOSHIKAZU USHIJIMA1 (1. HOSHI UNIVERSITY)
[2P-864(2PS-02-05)]Analysis of key molecular events during lung cancer progression using spatially-resolved multi-omics technologies
○Ayako Suzuki1, Junko Zenkoh1, Yutaka Suzuki1 (1. Univ Tokyo)
[2P-865]Integrative analysis of spatial and single-cell transcriptome data from endometriosis-associated ovarian cancer tissues
○Mami Shibata1, Yuji Kamei2, Keisuke Kawamoto3, Reiji Muto3,4,5, Makoto Hamasaki5, Yutaka Ueda2, Koichi Ohshima3, Fusanori Yotsumoto1 (1. Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan, 2. Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan, 3. Department of Pathology, School of Medicine, Kurume University, Kurume, Japan, 4. Department of Pathology, National Hospital Organization (NHO), Kumamoto Medical Center, Kumamoto, Japan, 5. Department of Pathology, Fukuoka University School of Medicine, Fukuoka, Japan)
[2P-866]Phenylalanine restriction increases BPA uptake and tRNAPhe-GAA levels in tumor cell lines under ATF4 stress response
○Rie Saba1,2, Yuki Tamari1,3,4, Kenta Yashiro2, Minoru Suzuki3, Hideya Yamazaki1, Kei Yamada1 (1. Dept. Radiol., KPUM, 2. Dept. Anat., KPUM, 3. KURNS, 4. Fujita Health Univ.)
[2P-867]Functional analysis of PTIP, an adaptor protein, in normal hematopoiesis and leukemogenesis.
○Yasuyuki Sera1, Masayuki Iwasaki1, Nobuhito Muramoto1,2, Miho Koizumi1, Hiroaki Honda1 (1. Institute of Laboratory animals, Field of Human Disease Models, Major in Advanced Life Sciences and Medicine Tokyo Women's Medical University, 2. Department of Urology, Juntendo University)
[2P-868]Mechanisms and functions of miR-375 mediated cell death
○Marino Imai1, Hisashi Hisatomi1 (1. Seikei university)
[2P-869]PARP inhibition-associated DNA replication stress confers vulnerability to ATR inhibition in SMARCA4-deficient lung adenocarcinomas
○Kimiyoshi Yano1, Megumi Kato1,2, Syoju Endo1,2, Taichi Igarashi1,3, Takashi Kohno4, Bunsyo Shiotani1 (1. Lab. of Genome Stress Signal., Natl. Cancer Ctr. Res. Inst., 2. Dept. of NCC Cancer Sci., Grad. Sch. of Med. & Dent. Sci., Tokyo Med. & Dent. Univ., 3. Div. of Mol. Biol., Grad. Sch. of Sci., Kitasato Univ., 4. Div. of Genome Biol., Natl. Cancer Ctr. Res. Inst.)
[2P-870]Analysis of the regulatory mechanism of glioblastoma microenvironment by RNA demethylase ALKBH family molecules
○Honoka Kitamura1, Manami Yamada1, Shuntaro Aoi1, Kaori Kitae1, Hiroaki Hase1, Kentaro Jingushi1, Yuko Ueda1, Nayuta Higa2, Tatsuhiko Furukawa3, Ryosuke Hanaya2, Kazutake Tsujikawa1 (1. Mol. Cell. Physiol., Grad. Sch. Pharm. Sci., UOsaka, 2. Neurosurgery, Grad.Sch. Med. Dent. Sci., Kagoshima Univ., 3. Pathol, Grad.Sch. Med. Dent. Sci., Kagoshima Univ.)
[2P-871]Prediction of metastasis based on gene expression in normal tissue adjacent to tumor
○Shinichiro Ono1, Takashi Makino1 (1. TOHOKU University)
[2P-872]Development of an in vitro immunotherapy efficacy assessment system for immune checkpoint inhibitors using a patient-derived canine bladder cancer organoids/immune cells co-culture model
○Ting-Wei Yu1, Haru Yamamoto1, Tatsuya Usui1, Kazuaki Sasaki1 (1. Tokyo University of Agriculture and Technology)
[2P-873]Progression of Human Gastric Cancer Organoids Controlled by the Heterogeneity of Phase II Enzyme Ligands as Stem Cell Therapy Model.
○yahan yang1,2,5, Kung-Kai Kuo5, Chia-Chen Ku1,2,3, Kenly Wuputra1,2,3, Deng-Chyang Wu4, Kazunari K. Yokoyama1,2,3 (1. Graduate institute of Medicine, KMU., 2. Regenerative Medicine and Cell Therapy Research Center, KMU., 3. Cell Therapy and Research Center, KMUH., 4. Division of Gastroenterology, Department of Internal Medicine, KMUH., 5. Division of General Surgery, E-DA Hospital.)
[2P-874]Radiosensitization effect of BACEI after γ-irradiation in cancer cells
○ZONGXIANG ZHANG1, Barkha Saraswat1, Zhongming Gao1, Ankitha Vadi Velu1, Ying Tong1, Mitsuko Masutani1 (1. Dept. Molecular & Genomic Biomed., CBMM, GSBS, Nagasaki Univ.)
[2P-875]MicroRNA analysis using formalin-fixed, paraffin-embedded tissues of bladder cancer surgical specimens
○Kimiaki Takagi1, Kazuki Taniguchi1, Yuka Maekawa1, Kenichi Minoshima1, Kentaro Suzuki2, Yoshifumi Yutoh3, Azumi Naruse4, Arizumi Kikuchi4 (1. Daiyukai General Hospital/Urology, 2. Daiyukai General Hospital/Clinical laboratory, 3. KANTO CHEMICAL CO.,INC., 4. Daiyukai Research Institution for Medical Science)
[2P-876]Cystatin A-mediated antitumor activity in murine models of pancreatic cancer
○Shingo Inagaki1, Alessandro Nasti2, Tuyen Thuy Bich Ho2, Akihiro Seki3, Keiko Yoshida1, Kosuke Satomura1, Tarou Yamashita3 (1. System biology, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, 2. Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, 3. Department of Gastroenterology, Kanazawa University Hospital)
[2P-877]Development of inhibitory peptides for Akt-PAK interaction and their application for anticancer drug
○Itsuki Senoo1, Keisuke Onishi2, Yukiko Gotoh3, Maiko Higuchi1 (1. Graduate School of Life Science, Rikkyo University, 2. Department of Chemistry and Biotechnology, University of Tokyo, 3. Graduate School of Pharmaceutical Sciences, University of Tokyo)
[2P-878]Identification of serum lipids as predictive marker for lenalidomide therapy in multiple myeloma patients
○Muneshige Tokugawa1, Masaki Ri2, Mine Fujimori1, Yuzuha Fujii1, Chisato Takahashi1, Shinsuke Iida2, Keiko Maekawa1 (1. Doshisha Women's College of Liberal Arts, 2. Nagoya City Univ.)
[2P-879]The microtubule polymerization inhibitor MMAE-conjugated catfish egg lectin selectively induced cell death in Gb3-expressing cancer cells
○Shigeki Sugawara1, kohtaroh Kikuchi1, Takeo Tatsuta1, Masahiro Hosono1 (1. Cell Recog., Inst. Mol. Biomembrane Glycobiol., Tohoku Med. Phram. Univ.)
[2P-880]Exploring EGFR-TKI resistance mechanisms using EGFR mutant lung cancer mouse model
○Masato Fujitani1,2, Iwao Shimomura3, Ai Takemoto1, Kadoaki Ohasi4, Ryohei Katayama1 (1. Div. Experiment. Chemother., Cancer Chemother. Ctr., JFCR, 2. Dept. CBMS, Grad. Sch. Front. Sci., Univ. of Tokyo, 3. Dept. Respirology Medicine, Chiba University, 4. Dept. Allergy and Respiratory Medicine, Okayama University)
[2P-881]Statistical mining of triple-negative breast cancer-specific nanobodies among huge libraries from immunized alpacas—inverse biomarker exploring technology
○Ryota Maeda1,2, Hiroyuki Yamazaki2, Ryoga Kobayashi1, Takayuki Watanabe1, Seishiro Yamamoto1, Kazuki Kasai1, Akihiro Imura1,2 (1. COGNANO, Inc., 2. Biorhodes, Inc.)
[2P-882]Inhibitory effect of a flavonoid compound on tumor progression via regulating lymph node sinus macrophages
○Yukio Fujiwara1, Toshiki Anami1, Toyohisa Iriki1, Daisuke Shiraishi1, Yoshihiro Komohara1 (1. Kumamoto University)
[2P-883]Elucidation of the dynamics of exosomes derived from pancreatic β cells using transgenic mice
○Yuna Shinotsuka1, Aisha Yokoi2, Ayano Goto1, Seitaro Yamashita3, Nanako Tsuji3, Shun-ichiro Asahara2, Yoshiaki Kido2 (1. Division of Metabolism and Disease, Department of Biophysics, Kobe University Graduate School of Health Sciences, 2. Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, 3. Medical Technology Major, Kobe University School of Medicine Faculty of Health Sciences)
[2P-884]Functional analysis of pancreatic beta cell-derived exosomes in diabetic state using type 2 diabetes model mice
○Ayano Goto1, Aisha Yokoi2, Yuna Shinotsuka1, Nanako Tsuji3, Seitaro Yamashita3, Shun-ichiro Asahara2, Yoshiaki Kido2 (1. Division of Metabolism and Disease, Department of Biophysics, Kobe University Graduate School of Health Sciences, 2. Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, 3. Medical Technology Major, Kobe University School of Medicine Faculty of Health Sciences)
[2P-885]Peroxiredoxin-6 secreted by skeletal muscle improves lipid metabolism in brown adipose tissue
○Kun Tang1, Yuki Komiya1, Yasuro Furuichi1, Nobuharu L. Fujii1, Yasuko Manabe1 (1. Department of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University)
[2P-886]Development of the In Vivo Iron Dynamics Visualization Tool “LiON”
○Ayato Maeda1,2, Akihiro Nita1,2, Toshiro Moroishi1,2 (1. Department of Molecular and Medical Pharmacology, Kumamoto Univ., 2. CMHA, Kumamoto Univ.)
[2P-887]Glycation Induced by Glyceraldehyde Triggers Rapid Degradation of CDC25A via the Neddylation Pathway
○Kenji Takeda1,2, Akiko Sakai-Sakasai1, Kouji Kajinami2, Masayoshi Takeuchi1 (1. Kanazawa Med. Univ., Med. Res. Inst., 2. Kanazawa Med. Univ., Dept. Cardiol.)
[2P-888]The search for a novel calorie restriction-induced mitochondrial signal peptidase
○Komachi Kato1, Yoshikazu Higami2,3, Masaki Kobayashi1,4 (1. Dept. Nut. Food. Sci., Ochanomizu Univ., 2. Dept. Med. Life. Sci., Tokyo Univ. Sci., 3. Ins. Bio. Sci., Tokyo Univ. Sci., 4. Ins. Hum. Life. Sci., Ochanomizu Univ.)
[2P-889]System-Wide Analysis of Skeletal Response to Nutrient Overload
○Aseel Marahleh1,3, Sherif Rashad2, Ren Jiayi3, Eisuke Kanao4, Shinichi Sato1, Fumitoshi Ohori3, Hideki Kitaura3 (1. Frontier Research Institute for Interdisciplinary Sciences, Tohoku Univ., 2. Dept. of Neurosurgical Engineering and Translational Neuroscience, Grad. Sch. of Biomed. Eng., Tohoku Univ., 3. Dept. of Orthodontics and Dentofacial Orthopedics, Grad. Sch. of Dentistry, Tohoku Univ, 4. Graduate School of Pharmaceutical Sciences, Kyoto Uni)
[2P-890]Chromosome 1 substitution strains, a new resource for pre-clinical MASLD mouse model development
○Juan Liang1, Xushan Yang1, Jie Zheng1, Yumeng Hou1, Xinyi Wu1, Zhong Chen1, Xiang Gao1 (1. GemPharmatech Co., Ltd.)
[2P-891]Accumulation of mtDNA with a large-scale deletion increases mitochondrial autophagy in cardiac muscle tissues
○Koichi Sadotomo1, Kaori Ishikawa2, Kazuto Nakada2 (1. Master's Programs in Biology, Grad. Sch. Science and Technology, University of Tsukuba, 2. Institute of Life and Environmental Sciences, University of Tsukuba)
[2P-892]Regulation of Myokines by Fatty Acids in Mouse Skeletal Muscle
○YUHO MIZUSEKI1, Yuri Sato-Ishiuchi1, Ayaka Shinozaki2, Erika Hiraiwa2, Taku Nedachi1,2 (1. Graduate School of Life Sciences, Toyo University, 2. Faculty of Life Sciences, Toyo University)
[2P-893]Angiotensin II participates in mitochondrial thermogenic functions via the activation of glycolysis in chemically induced human brown adipocytes.
○Yukimasa Takeda1 (1. Dept. of Cell. Regen. Med., Grad. Sch. of Med. Sci., Kyoto Pref. Univ. of Med.)
[2P-894]Glucose and lipid metabolism in cells under high glucose environments
○Naoko Niimi1, Kazunori Sango1 (1. Tokyo Metropolitan Institute of Medical Science)
[2P-895]Investigation into the mechanism by which TPO mutations accompanied by conformational changes due to loss of disulfide bonds cause congenital hypothyroidism
○Fumiyoshi Yakou1, Hirotsugu Suwanai1, Hajime Iwasaki1, Hiroyuki Sakai1, Kohsuke Kanekura2, Satoshi Narumi3, Ryo Suzuki1 (1. Dept. of Diab. Metabo.& Endocrinol., Tokyo Medical Univ., 2. Dept. of Pharma, Tokyo Medical Univ., 3. Dept. of Pediatrics, Keio Univ. Sch. of Med.)
[2P-896]Function and regulatory mechanism of organismal homeostasis by dietary zinc restriction
○Souto Kitazawa1,2, Yuka Fujita1,2, Hina Kosakamoto1, Fumiaki Obata1,2 (1. RIKEN Center for Biosystems Dynamics Research, 2. Graduate school of biostudies, Kyoto Univ.)
[2P-897]Effect of quercetin on contraction force and molecular basis in skeletal muscle organoid
Nozomi Tanaka1, Naoko Matsui2, Yukihiro Oritani2, Naoki Iemoto2, Sho Yokoyama1, Toshiya Fujisato1, ○Tomohiro Nakamura1 (1. Osaka Institute of Technology, 2. Morinaga & Co., Ltd.)
[2P-898]Development of new treatment for type 1 diabetes using devices with nanosheets
○Atena Endo1, Nanami Zushi1, Mahiro Suzuki1, Nobuaki Shiraki1, Toshinori Fujie1, Shoen Kume1 (1. Science Tokyo)
[2P-899]Nrf2 regulates SIRT1 protein expression but not contribute to improve glucose metabolism in muscle.
○Miu Yasutake1, Mami Yamada1, Mitsuharu Okutsu1 (1. Nagoya City Univ.)
[2P-900]Development of Vitamin K Derivatives with 3CL Protease and RdRp Inhibitory Effects for the Treatment of COVID-19
○Mayu Hayakawa1, Ryohoto Koharazawa1, Taiki Honma1, Kazuki Takeda2, Yoshitomo Suhara1, Yoshihisa Hirota1 (1. Department of Bioscience and Engineering, College of Systems Engineering and Science, Shibaura Institute of Technology, 2. School of Veterinary Medicine, Kitazato University, Japan.)
[2P-901]MAFB in Macrophages Regulates Sympathetic Neuron Density and Thermogenesis in Cold-Induced Brown Adipose Tissue
○Michito Hamada1, Manoj Kumar Yadav1, Natalia Gogoleva1, Megumi Ishida1, Ching-Wei Liao1, Maho Kanai1, Akihiro Kuno1, Satoru Takahashi1 (1. University of Tsukukba)
[2P-902(2PS-13-07)]The relationship between the metabolism of branched-chain amino acid and aging
○Kazuki Irie1, Yuma Aramaki1, Hideru Obinata2, Shinya Honda3, Takuro Horii4, Satoko Arakawa3, Aiko Tsuchida5, Junki Hoshino1, Ryosuke Kobayashi4, Takashi Izumi6, Izuho Hatada4, Shigeomi Shimizu3, Yoji Andrew Minamishima1, Akimitsu Konishi1 (1. Dept. Biochem. Gunma Univ., 2. Education & Research Support Center. Gunma Univ., 3. Dept. Pathol. Cell Biol. TMDU., 4. Biosignal Genome resourse Center, Gunma Univ., 5. Faculty of Medicine. Gunma Univ., 6. Faculty of Healthcare, Teikyo Heisei Univ.)
[2P-903]Dysregulation of cholesterol metabolism in α-Klotho KO mice
○Hirofumi Sogabe1, Chiaki Abe1,2, Yo-ichi Nabeshima1,2 (1. Dept. of Aging Sci and Med., Kyoto Univ, 2. FBRI)
[2P-904]Novel mechanism of mitochondrial homeostasis mediated by the processing peptidase MIPEP
○Mamiko Ishimatsu1, Yuka Nozaki1, Yuhei Mizunoe1, Masaki Kobayashi2,3, Yoshikazu Higami1,4 (1. Dept. of Pharm. Sci., Grad. Sch. of Pharm. Sci., Tokyo Univ. of Sci., 2. Dept. of Nutrition and Food Sci., Grad. Sch. of Humanities and Sci., Ochanomizu Univ., 3. Inst. for Human Life sci., Ochanomizu Univ., 4. Div. of Cell Fate Reg., Res. Inst. for Biomed. Sci., Tokyo Univ. of Sci.)
[2P-905]xCT is an exacerbating factor for obesity-induced inflammation and decreases adiponectin
○Yugo Kato1, Yosuke Horikoshi1, Kazuhiro Nakaso1 (1. Division of Biochemistry, Department of Pathophysiological and Therapeutic Sciences, Faculty of Medicine, Tottori University)
[2P-906]The impact of dietary restriction on lipid metabolism and sex differences in Drosophila melanogaster
○Shotaro Yamagiwa1, Hinako Fukatsu2, Kazutaka Akagi3, Keiichi Koizumi3 (1. Dept. of Pharma. Sci., Univ. of Toyama, 2. Dept. of Pharma. Sci., Grad. Sch. of Med. and Pharma. Sci., Univ. of Toyama, 3. Inst. of Nat. Med., Univ. of Toyama)
[2P-907]Control of blood glucose levels by D-Serine in lean mice
○Akira Toda1, Kisara Ueda1, Koki Daido1, Daichi Fuchisawa1, Futoshi Furuya1, Shinsuke Mohri1, Eri Mukai1 (1. Ritsumeikan University Graduate School of Life Science)
[2P-908]Enhanced insulin secretion by constitutive activation of GPCRs in pancreatic beta cells
○Ryoya Yamamoto1, Yuta Kato1, Daisuke Yokoyama, Eri Mukai1 (1. Ritsumeikan university)
[2P-909]The role of CREG1 for glucose metabolism in liver
○So Nishimoto1, Daiki Shimizu2, Ayumi Goto3, Hitoshi Yamashita1,2 (1. Chubu Univ. Graduate School of Life and Health Sciences, 2. Chubu Univ., 3. TOYOHASHI SOZO Univ.)
[2P-910]Elucidation of the mechanisms underlying heterogeneity in TH expression in β-cells
○Kota Inoue1, Shigemi Tominaga1, Fumiya Uefune1, Yuuki Itatani1, Nobuaki Shiraki1, Daisuke Sakano1, Shoen Kume1 (1. Science tokyo)
[2P-911]Chronic effects of pyroglutamyl leucine in obesity
○Shun Sugahara1, Saki Shirako1, Koki Daido1, Daichi Fuchisawa1, Futoshi Furuya1, Shinsuke Mohri1, Eri Mukai1 (1. Ritsumeikan Univ. Graduate School)
[2P-912]Glutamine-polyamine metabolic axis mechanisms of cell growth in cancer cells
○Mayu Asao1,2, Tomoya Matushita1,2, Sho Aki2, Tsuyoshi Osawa1,2 (1. Dept. Eng., Univ. of Tokyo, 2. Dept. of Integrative Nutriomics and Oncology RCAST, Univ. of)
[2P-913]Elucidation of the mechanism of myogenic diseases using natural ingredients derived from kuwai
○Kazu Hinenoya1, Yumiko Nakayama1, Mizuki Arai1, Yumeno Kubota1, Miya Ishijima1, Haruhiko Sakiyama1 (1. SENRI KINRAN Univ.)
[2P-914]Analysis of the relationship between the amount of intracellular polysulfide and insulin sensitivity
○Misuzu Nakamura1 (1. Doshisha University)
[2P-915]Exploration of genetic causes of biparental placental mesenchymal dysplasia
○Ayaka Murase1, Takashi Ohba2, Hiroyuki Mishima3, Koh-ichiro Yoshiura3, Hidenobu Soejima1 (1. Saga university, 2. Kumamoto University, 3. Nagasaki University)
[2P-916]Statistical results of a comprehensive genomic analysis of 1,560 patients with rare or undiagnosed diseases at a single centre
○Tadashi Kaname1,2,7, Kumiko Yanagi1,7, Arisa Igarashi1, Taiga Aoki1, Takaya Iida1, Masahiko Yamamori1, Kazuhito Satou1, Yasutsugu Chinen3,7, Yoko Aoki4,7, Ko-ichiro Yoshiura5,7, Nobuhiko Okamoto6,7, NCCHD GM consortium IRUD7, Yoichi Matsubara1,7 (1. Department of Genome Medicine, National Center for Child Health and Development, 2. Allergy Center, NCCHD, 3. Dept Ped, Grad Schl Med, Univ Ryukyus, 4. Dept Med Genet, Tohoku Univ Schl Med, 5. Dept Hum Genet, Nagasaki Univ Grad Schl Biomed Sci, 6. Dept Med Genet, OWCH, 7. IRUD NCCHD-GM consortium)
[2P-917]Functional Analyses of X-linked Alport syndrome rats using the rGONAD method
○Masumi Namba1, Tomoe Kobayashi1, Mayumi Kohno1, Hiroaki Hiramatsu1, Takayuki Koyano1, Makoto Matsuyama1 (1. Shigei Medical Reserch Institute)
[2P-918]Investigation of the pathological role of iron in cholestatic liver injury
○Yudai OHTA1, Yohei KANAMORI1, Toshiro MOROISHI1,2 (1. Dept. of Mol. Pharmacol., Grad. Sch. of Life. Sci., Univ. of Kumamoto, 2. Ctr. for Metab. Regul. of Hlth. Aging., Grad. Sch. of Life. Sci., Univ. of Kumamoto)
[2P-919]CdLS and CHOPS syndrome are commonly characterized by cohesin loss and accumulation of the super elongation complex
○Toyonori Sakata1,2,3, Masashige Bando1, Katsuhiko Shirahige1,2,3 (1. Lab. of Genome Struc. and Func., IQB, Univ. of Tokyo, 2. Karolinska Inst., CMB, 3. Karolinska Inst., MedH, BioNut)
[2P-920]Ectodermal Dysplasia Model by CRISPR/Cas9-based Gene Targeting in the Carboxy-Terminus of p63 gene
○Daisuke Suzuki1, Junya Yamamoto1, Yoko Horikawa1, Motohito Goto2, Riichi Takahashi2, Ryoji Ito2, Norihiko Ito3, Sakurako Neo4 (1. Kobe Gakuin University, Faculty of Nutrition, 2. Central Institute for Experimental Animals, 3. Tottori University Veterinary Medical Center, 4. Azabu University School of Veterinary Medicine)
[2P-921]Gene expression analysis of neurons derived from iPSCs with TDP-43 mutation
○Nanami Amari1, Asuka Kamei2, Hitoshi Ishiguro2,3, Tohru Sugawara1 (1. Graduate School of Medical Life Science, Yokohama City University, 2. Kanagawa Institute of Industrial Science and Technology, 3. Graduate School of Medicine, Yokohama City University)
[2P-922]Effects of radiation on mammary tissue in the Brca1 mutant rat model: RNA sequencing analysis for exploring carcinogenesis-associated gene expression changes
○Yuzuki Nakamura1,2, Atsuko Ishikawa2, Kazuhiro Daino2, Yukiko Nishimura2, Kento Nagata2, Masaru Takabatake1,2, Kazumasa Inoue1, Tatsuhiko Imaoka1,2 (1. Tokyo Metropolitan Univ., 2. Institute for Radiological Science, QST)
[2P-923]Research on pathological transition of liver using mouse model of mitochondrial disease
○Takayoshi Kuriyama1, Daiki Miyata1, Haruna Tani3, Kaori Ishikawa1,2, Kazuto Nakada1,2 (1. Grad. Sch. of Sci. and Tech., Life and Earth Sci., Biol. Prog., Univ. of Tsukuba., 2. Inst. of Life and Env. Sciences., Univ. of Tsukuba., 3. Dept. of Modomics Biol. & Med., IDAC, Tohoku Univ.)
[2P-924]A novel mutation (c.208T>C) in SLC45A2 causes dominant oculocutaneous albinism type 4
○Hirotaro Urushibata1, Nobuyuki Shimizu1, Hiroyuki Yatsuka2, Masanori Inoue3, Hiroshi Shiraishi1, Kenji Ihara3, Toshikatsu Hanada1 (1. Dept. of Cell Biol., Fac. of Med., Oita Univ, 2. Dept. of Oph., Fac. of Med., Oita Univ., 3. Dept. of Ped., Fac. of Med., Oita Univ.)
[2P-925]Regulation of Pgk, the Drosophila homologue of PGK1, a candidate gene for Parkinson's disease, by the hypoxia-inducible factor sima / HIF1α
○Tomonori Ichioka1, Kotomi Okuno1, Takashi Kasai2, Fukiko Morii2, Hideki Yoshida1 (1. Kyoto Institute of technology, 2. Kyoto Prefectural University of Medicine)
[2P-926]Profiling Genome Editing Outcomes in Individual Human iPS Cells
○Go Takahashi1,2, Minato Maeda1,3, kayoko Shinozaki1,3, Gakuro Harada4, Saburo Ito4, Yuichiro Miyaoka1,3,5 (1. Regenerative Medicine Project, Tokyo Metropolitan Institute of Medical Science, 2. Department of Animal Science, Faculty of Agriculture, Tokyo University of Agriculture, 3. Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 4. Yamaha Motor Co., Ltd., 5. Graduate School of Humanities and Sciences, Ochanomizu University)
[2P-927]The splice pattern analysis of EYA4, the gene responsible for hereditary hearing loss, DFNA10
○Kentaro Ohara1,2, Kazuaki Nagao2,3, Hiroko Yanagisawa2, Hideki Mutai2, Chika Saegusa2,3, Masato Fujioka2,3 (1. Kitasato Univ. Sch. of Med., 2. Dept. Mol. Genent., Kitasato Univ. Sch. of Med., 3. Dept. Mol. Genent., Kitasato Univ. Grad. Sch. of Med. Sci.)
[2P-928]LETMD1 knockout induces ferroptotic cell death and neuroinflammation in the brain.
○JIWON KO1, ZAE YOUNG RYOO2 (1. Institute of Life Science and Biotechnology, Kyungpook National University, Daegu, 41566, Republic of Korea., 2. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea.)
[2P-929]The reduction of HSPA9 worsens the symptoms and increases cell death in inflammatory colitis induced by DSS
○Soyoung Jang1, Zae Young Ryoo1 (1. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea)
[2P-930]A novel plasmid set and a method for high-density crop hydroponics in a plant incubator for producing multiple genome editing crop
○Masaharu Kuroda1, Hyungjun Park1, Tetsuo Oikawa1, Momoko Chiba1 (1. Inst. Agrobiol. Sci., NARO)
[2P-931]Screening of compounds that inhibit pollen germination and pollen tube growth
○Ayaka Kawahara1, Ayato Sato2, Kenichiro Itami2, Shuh-ichi Nishikawa3 (1. Grad. Sch. Sci. Tech., Niigata Univ., 2. ITbM, Nagoya Univ., 3. Fac. Sci., Niigata Univ.)
[2P-932]Identification of CBL4-interacting proteins under salt stress using proximity-dependent biotinylation enzyme
○Mana Hamada1, Ryosuke Hori1, Sota Shinohara1, Kohei Nishino2, Hidetaka Kosako2, Akira Nozawa1, Tatsuya Sawasaki1 (1. Proteo Science Center, Ehime University , 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
[2P-933]Pollen tube rupture mechanism caused by bacteria living in flower nectary
○Yoshinobu Kato1,2, Hiroki Miura1, Seiji Takayama1, Sota Fujii1,3 (1. The University of Tokyo, 2. JST PRESTO, 3. SunRiSE)
[2P-934]Mechanism of specific plant immune induction by flagellins from Acidovorax avenae
○Hikari Matsumura1, Marvin Axel Wijaya2, Yuya Katsuragi2, Yukihiko Nakagawa1, Takahiko Murakami1, Fang-Sik Che1,2,3 (1. Grad. Sch. of Biosci., Nagahama Inst. of Bio-sci and Tech., 2. Dept. of Bio-sci., Nagahama Inst. of Bio-sci and Tech., 3. GERI, Nagahama Inst. of Bio-sci and Tech.)
[2P-935]Investigating the Content Distribution of Areca Nut-Specific Alkaloids Across Different Maturity Stages
○Yun-Wei Chen1, Ting-Yu Kuo2, Yin-Ting Kao1, Chiao-Jou Yu1, Rajendra Bose Muthukumaran3, Chiung-Wen Hu2, Mu-Rong Chao1, Yuan-Jhe Chang1 (1. Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan, 2. Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan, 3. Department of Chemistry, Mizoram University, Aizawl 796004, India)
[2P-936]Molecular Study of Substrate Specificities and Inhibitor Sensitivity of S-RNase in Petunia
○Yu Wang1, Yoshinobu Kato1, Shuhei Kusano2, Shinya Hagihara2, Seiji Takayama1, Sota Fujii1 (1. The University of Tokyo, 2. RIKEN)
[2P-937]Recognition mechanism of rice immunity-inducing factor, flagellin CD2–1 by FliRK2
○Ryunosuke Yamamoto1, Koki Wataya1, Koki Iba1, Yuya Katsuragi2, Fang-Sik Che1,2,3 (1. Grad. Sch. of Biosci., Nagahama Inst. of Bio-sci and Tech., 2. Dept. of Bio-sci., Nagahama Inst. of Bio-sci and Tech., 3. GERI, Nagahama Inst. of Bio-sci and Tech.)
[2P-938]Functional Analysis of genome editing plants targeting for the Thrum specific gene in heteromorphic self-incompatibility in Linum perenne.
○Maki Tanaka1, Kohji Murase1,3, Masaaki Yamaguchi2, Ken Itakura1, Yuka Kimura1, Takuya Nagae1, Yoshinobu Kato1,3, Sota Fujii1,4, Hiroshi Shiba2, Seiji Takayama1 (1. Dept. of Applied Biol. Sci., Grad. Sch., of Agric Life Sci., Tokyo Univ., 2. Tsukuba-Plant Innovation Research Center Tsukuba, Univ., 3. Precursory Research for Embryonic Science and Technology, 4. Suntory Rising Stars Encouragement Program in Life Science)
[2P-939]Anti-inflammatory compounds of Chrysanthemum indicum capitulum identified using primary cultured rat hepatocytes
○Keita Minamisaka1, Cheng Li1, Saki Shirako1, Airi Fujii1, Teruhisa Kawamura1, Yukinobu Ikeya2,3, Mikio Nishizawa1 (1. Ritsumeikan University , 2. Daiichi University of Pharmacy, 3. Ritsumeikan University)
[2P-940]Genome-wide investigation of pollen factor(s) interact with pistil pre-zygotic reproductive barrier factor in Arabidopsis
○Kazuki Hirano1, Takuya Nagae1, Hiroki Miura1, Seiji Takayama1, Sota Fujii1 (1. Tokyo Univ.)
[2P-941]The effect of the Foehn phenomenon on gene expression and grain quality during the ripening process of rice cultivar ‘Koshihikari’
○Takeshi Shiraya1, Toru Tsuchida2 (1. Niigata Agr. Res. Inst., 2. Niigata Crop Res. Center)
[2P-942]Exploration of the advantage in heterogeneous spatial distribution of the chloroplast photosynthetic proteins: a simulation study
○Natsuki Ichikawa1,2, Yasuhiro Naito3,1,2 (1. Syst. Biol. Program, Grad. Sch. Media Gov., Keio Univ., 2. Inst. Adv. Biosci., Keio Univ., 3. Dept. Environ. Info. Stud., Keio Univ.)
[2P-943]The causative gene for monogerm seed is explored and characterized through comparative analysis of polymorphisms among dominant/recessive alleles in sugar beet (Beta vulgaris L.) lines.
○Ayumi Kuno1, Kotaro Hiroki1, Tsubasa Narihiro2, Hiroaki Matsuhira2, Tomohiko Kubo1, Yosuke Kuroda2, Kazuyoshi Kitazaki1 (1. Hokkaido Graduate School of Agriculture, 2. NARO,HARC)
[2P-944]Staging of rice anther developmental process by time-course RNA-Seq using individual differences
○Akiha Kagehira1, Makiko Kawagishi2, Makoto Kahima1 (1. Toho Univ., 2. Institute of Agrobiological Sciences, NARO)
[2P-945]A mutation in the intracellular vesicle transport protein Vps4 in cucumber indicates immunity to multiple viruses
○Yuya Suzuki1, Kaito Takamatsu1, Akiho Kobayashi1, Masashi Amano2, Yoshiyuki Imura1 (1. College of Bioresource Sciences, Nihon University, 2. Saitama Gensyu Ikuseikai Co.,Ltd)
[2P-946]Molecular mechanisms of the rice NLR Xa1-mediated immune activation
○Ayaka Yoshihisa1, Satomi Yoshimura1, Kei Nishikawa1, Motoki Shimizu2, Koji Yamaguchi1, Yoshiyuki Hirano3, Masatsugu Toyota4, Toshiyuki Shimizu3, Tsutomu Kawasaki1 (1. Grad. Sch. Agr., Kindai Univ,, 2. Iwate. Biotech. Res. Cen,, 3. Grad. Sch. Pharm. Sci., Univ. Tokyo, 4. Fac. Sci., Saitama Univ,)
[2P-947]Analysis of the inhibitory effect of ethylene response factor NtERF#229 on tomato mosaic virus proliferation.
○Maho Kawakami1, Nobumitsu Sasaki1,2, Yasuhiko Matsushita1,2 (1. Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. & Tech., 2. Gene Res. Center, Tokyo Univ. of Agr. & Tech.)
[2P-948]Expression of human Caspase-3 gene induces cell death and suppresses potato X virus infection in plants.
○Yuki Fujii1, Nobumitsu Sasaki1,2, Yasuhiko Matsushita1,2 (1. United Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. & Tech., 2. Gene Res. Center, Tokyo Univ. of Agr. & Tech.)
[2P-949]Role of CREB in the hypoxia/reoxygenation-induced catch-up growth in zebrafish embryo
○Aira Sasaki1, Hiroyasu Kamei1 (1. Kanazawa Univ.)
[2P-950]Accumulation and propagation of pathological mitochondrial variants in normal skin
○Kohta Nakamura1, Yasunari Sato2, Masao Hashimoto2, Naoyuki Matsumoto1, Yasushi Okazaki1, Yasuo Miyoshi3, Hiroki Nagase1 (1. Diagnostics and Therapeutics of Intractable Diseases, Intractable Disease Research Center, Graduate School of Medicine, Juntendo University, 2. Rohto, Fundamental Technology, Dermatology, 3. Department of Breast and Endocrine Surgery, Hyogo Medical University Hospital)
[2P-951]Maternal Western pattern diet affects radio-sensitivity of hematopoietic tissues of offspring
○Takanori Katsube1, Masahiro Murakami1, Cuihua Liu2, Takamitsu Morioka1, Shizuko Kakinuma1, Bing Wang1 (1. NIRS, QST, 2. QST Hospital, QST)
[2P-952]Study on the Non-Thermal Effects of the Sub-Terahertz Wave Irradiation on the Caenorhabditis elegans
○RYOHEI Kuriyama1, Masahiro Imashimizu2, Yuka Ikemoto3, Masahiko Kuramochi1 (1. Dept. of Quant. Sci. Eng., Grad. Sch. of Sci., Univ. of Ibaraki, 2. Cellular and Molecular Biotechnology Research Institute, AIST, Tsukuba, Japan, 3. Japan Synchrotron Radiation Research Institute (JASRI))
[2P-953]Knockout cell-based library screening for adeno-associated virus vector production enhancers
○Yoshitaka Miyagawa1, Yukage Kobari1, Satsuki Anzai1, Yuriko Sato1, Yuka Oyama1, Mashito Sakai1, Takashi Okada2 (1. Nippon Medical School , 2. Tokyo University)
[2P-954]The proper subset responsible for erythropoietin production among renal fibroblasts exhibits resistance to transformation into myofibroblast
○Taku Nakai1, Norio Suzuki1 (1. Tohoku Univ. Graduate School of Medicine, Oxygen Biology)
[2P-955]Development of mutation allele-specific reframe genome editing gene therapy for retinitis pigmentosa
○Kosuke Fujita1, Kazuhisa Yamada1, Kiichi Hirazawa1, Koji M Nishiguchi1 (1. Nagoya University)
[2P-956]Micropattern Address Tag Sheet for Spatial Analysis of Tissue Slices
○Daichi Hirai1, Koki Ueta2, Hidekuni Takao1, Kyohei Terao1 (1. Graduate School of Science for Creative Emergence, Kagawa University, 2. Dept. of IMSE, Kagawa Univ.)
[2P-957]Quantification of stress accumulation and understanding novel stress responses through serum protein AIM
○Satoko Arai1, Keisuke Yasuda1, Toru Miyazaki1 (1. The Institute for AIM Medicine)
[2P-958]Lipid- and Glucose-lowering Effects of Rhamnan Sulphate with altered Gut Microbiota.
○Yasuhito Shimada1,2, Toshinari Ishimaru3, Kaoru Nishiura4, Koichi Matsuda4, Ryota Uchida4, Hiroko Nakayama3, Izumi Matsuoka3, Masahiro Terasawa4, Norihiro Nishimura2,3, Zang Liqing2,3 (1. Mie Univ. Med Sch. Int Pharmacol, 2. Mie Univ. Zebra Res., 3. Mie Univ. Regional Innov., 4. Konan Chem.)
[2P-959]Development of a New Advanced Search System for Bioresources
○Tatsuya Kushida1, Daiki Usuda1, Toyoyuki Takada1, Hiroshi Masuya1 (1. Integrated Bioresource Information Division, RIKEN BioResource Research Center)
[2P-960]Molecular mechanism and phenotype analysis of mouse lethality due to conditional knockout of protein cross-linking enzyme TG1
○Atsuki Takahashi1, Ryota Tamura1, Hideki Tatsukawa1, Kiyotaka Hitomi1 (1. Graduate School of Pharmaceutical Sciences, Nagoya University)
[2P-961]Phocaeicola dorei and Phocaeicola vulgatus prevent atherosclerosis by regulating gut immunity
○Hitomi Nakashima1, Takuo Emoto2, Yasunori Yonejima1, Naofumi Yoshida2, Tomoya Yamashita2,3 (1. Noster Inc., 2. Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 3. Department of Advanced Medical Science, Kobe University Graduate School of Science, Technology and Innovation)
[2P-962]The role of the Juvenile hormone signaling pathway in the maternal diapause regulation in the parasitic jewel wasp, Nasonia vitripennis
○Suguru Ikeda1, Yoshiaki Nishiya1, Ayumu Mukai2 (1. Div. of Life Sci., Grad. Sch. of Sci. and Eng., Setsunan Univ., 2. Dept. of Biol., Grad. Sch. of Sci., Osaka Metropolitan Univ.)
[2P-963]Mechanism of body size decrease in C. elegans with Mg2+ efflux transportercnnm mutation
○Osamu Hashizume1, Yosuke Funato1, Hiroaki Miki1 (1. Kyoto University)
[2P-964]Apoptotic mechanism-based functional liposome for the treatment of inflammatory diseases
○Jeong-Hun Kang1, Takahito Kawano2, Masaharu Murata2, Riki Toita3 (1. NCVC Res. Inst., 2. Adv. Innovation Center, Kyushu Univ., 3. Biomed. Res. Inst. AIST)
[2P-965]Role of Prohibitin and Prohibitin 2 on the chondrocyte differentiation
○Yu Hiromoto1, Ryota Hirose1, Ryuji Hara1, Ryo Igarashi1, Nobuyuki Shimohata2, Toshiya Hayano1 (1. Ritsumeikan Univ. Col. of Life Sci., 2. Kanagawa Univ. of Human Services)
[2P-966]Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia
○Mitsuharu Okutsu1, Mami Yamada1, Eiji Warabi2, Oishi Hisashi3 (1. Nagoya City Univ. Grad Sch of Sci., 2. Tsukuba Univ., 3. Nagoya City Univ. Grad Sch of Med.)
[2P-967]Longitudinal analysis of mitochondrial function in a MASH mouse model
○Akiko Yamada1, Naozumi Ishimaru2, Masatake Asano1 (1. Nihon Univ., 2. Tokyo Medical and Dental Univ.)
[2P-968]Liver Homogenate and Sulfhydrylated Albumin Mitigate APAP Hepatotoxicity
○Xin Wang1, Yijun Xu1, Jian Yao1 (1. University of Yamanashi)
[2P-969]Initiatives for the International Integration and Sharing of Rare Disease Information through the Nanbyo Disease Ontology (NANDO) and the Portal Site NanbyoData
○Terue Takatsuki1, Jae-Moon Shin1, Tatsuya Kushida2, Atsuo Kikuchi3, Toyofumi Fujiwara1 (1. ROIS-DS, DBCLS, 2. RIKEN, BRC, 3. Dept. of Pediatrics, Tohoku Univ. Hosp.)
[2P-970]Understanding of bone loss mechanism in normal mice using mathematical analysis
○Marwa Akao1, Kei Gouchi2,3, Masahiro Shinohara2, Shingo Iwami1, Shoya Iwanami1 (1. Nagoya University, 2. National Rehabilitation Center For Persons with Disabilities, 3. Tokyo Medical and Dental University)
[2P-971]Genetics in tardigrades: Analysis of albino mutation
○Takekazu Kunieda1 (1. Univ of Tokyo)
[2P-972]Large-scale in vitro screening of BioBank Japan human sera on cellular phenotypes by staining multiple organelles.
○Yoji Sagiya1, Chizu Tanikawa1, Hiromi Tsuru2, May Thi Anh Ta1, Koichi Matsuda1 (1. Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2. Inst. of Medial Sci., Univ. of Tokyo)
[2P-973]Functional analysis of new tolerance candidate genes in tardigrade by CRISPR/Cas9
○Jiang Dangchen1 (1. Tokyo Univ.)
[2P-974]A Novel Liver-Specific Knockdown Mouse Model for Functional Analysis of Genes Related to Glucose Metabolism
○Hiromi Miura1, Masato Ohtsuka1 (1. Divi. of Bas. Med. Sci. and Mol. Med., Tokai Univ. Sch. of Med.)