The 47th Annual Meeting of the Molecular Biology Society of Japan
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Mini-Symposium : [3MS-04] The origin of nuclear envelope biology and the new challenges: The basis of the nuclear envelope provides insights into life phenomena and diseases

[3MS-04]【J】The origin of nuclear envelope biology and the new challenges: The basis of the nuclear envelope provides insights into life phenomena and diseases

Fri. Nov 29, 2024 3:10 PM - 4:30 PM JST
Fri. Nov 29, 2024 6:10 AM - 7:30 AM UTC
Room 4(Fukuoka International Congress Center, 4F 404+405+406)
Organizer: Miki Matsumura (Ehime Prefectural University of Health Sciences), Takeshi Shimi (Kanazawa University )
In eukaryotes, the nuclear envelope regulates nuclear functions by enclosing chromatin higher-order structures. Genetic mutations in nuclear membrane-associated proteins lead to intractable diseases known as nuclear envelopathies. This symposium will focus on the life phenomena related to these diseases, such as metabolic regulation, inflammatory reaction and immune response, to present the frontiers of nuclear envelope biology, which are conducted by cross-sectional studies including molecular structure analysis, image analysis, bioinformatics and clinical specimen analysis. The discussion will revolve around the latest findings, emphasizing the basic structure and functions of the nuclear envelope.
3:10 PM - 3:12 PM JST(6:10 AM - 6:12 AM UTC)

Introduction

3:12 PM - 3:25 PM JST(6:12 AM - 6:25 AM UTC)

[3MS-04-01]Nanoendoscopy-AFM measurement of the effect of epithelial-mesenchymal transition on nuclear membrane elasticity in the living cell

○Takehiko Ichikawa1, Akiko Kudo1, Yohei Kono1, Takeshi Shimi1, Takeshi Fukuma1 (1. Kanazawa Univ. NanoLSI)
Comment()
3:25 PM - 3:38 PM JST(6:25 AM - 6:38 AM UTC)

[3MS-04-02]Regulatory mechanisms of chromatin structure by nuclear lamina factors

○Naoki Horikoshi1, Ryosuke Miyake1,2, Chizuru Sogawa-Fujiwara1, Mitsuo Ogasawara1, Yoshimasa Takizawa1, Hitoshi Kurumizaka1,2 (1. IQB, The Univ. of Tokyo, 2. Grad. Sch. of Sci., The Univ. of Tokyo)
Comment()
3:38 PM - 3:51 PM JST(6:38 AM - 6:51 AM UTC)

[3MS-04-03]Mechanisms of Heart Disease Caused by LMNA Mutations and Potential Therapeutic Applications

○Masamichi Ito1 (1. The University of Tokyo)
Comment()
3:51 PM - 4:04 PM JST(6:51 AM - 7:04 AM UTC)

[3MS-04-04]The morphological changes of the nuclear membrane regulating nuclear lipid droplets

○Yuki Ohsaki1, Nobuhiro Wada1 (1. Sapporo Med. Univ., Anatomy1)
Comment()
4:04 PM - 4:17 PM JST(7:04 AM - 7:17 AM UTC)

[3MS-04-05]Plant nuclear pore complex proteins are involved in centromere distribution

○Nanami Ito1, Takuya Sakamoto2,3, Yuka Oko3, Hikaru Sato1, Shigeru Hanamata2, Yuki Sakamoto4, Sachihiro Matsunaga1 (1. Dept. of Integr. Biosci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Dept. of Sci., Fac. of Sci., Kanagawa Univ., 3. Dept. of Appl. Biol. Sci., Fac. of Sci. and Tech., Tokyo Univ. of Sci., Japan, 4. Dept. of Biol., Fac. of Sci., Shinshu Univ., Japan)
Comment()
4:17 PM - 4:30 PM JST(7:17 AM - 7:30 AM UTC)

[3MS-04-06]Autophagic degradation of nuclear components: mechanisms and physiological significance

○Hitoshi Nakatogawa1 (1. Science Tokyo)
Comment()
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