Session Details

[1P]Poster Presentation 1

Wed. Dec 3, 2025 5:00 PM - 7:00 PM JST
Wed. Dec 3, 2025 8:00 AM - 10:00 AM UTC
Poster & Exhibition Venue (Pacifico Yokohama Exhibition Hall)

[1P-002]Click-qPCR: an interactive real-time quantitative PCR data analysis web tool that can be completed with a few clicks

○Azusa Kubota1, Atsushi Tajima1 (1. Kanazawa University, Graduate School of Advanced Preventive Medical Sciences)
Comment()

[1P-003(1AS-08-06)]Systematic analysis of novel heat stress-related long non-coding RNAs through FANTOM6 datasets and meta-analysis of public transcriptome data

○Sora Yonezawa1, Takeya Kasukawa2,3, Hidemasa Bono1,3 (1. Hiroshima Univ., 2. RIKEN IMS, 3. HUGE)
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[1P-004]Pseudogenization of Aqp10 in Cetartiodactyla

○Nodoka Nagai1, Akira Kato1 (1. Institute of Science Tokyo)
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[1P-005]NMR analysis of the interaction between DNA aptamer containing artificial base Ds and vascular endothelial growth factor VEGF165

○Renji Takahashi1, Naohiro Kobayashi2, Tomomi Nagahama1, Tatsuhiko Someya3, Miyuki Hori3, Taiichi Sakamoto1 (1. Chiba institute of technology, 2. RIKEN, 3. TAGCyx Biotechnologies Inc.)
Comment()

[1P-007]Evaluation of the immunostimulatory activity of Levilactobacillus brevis

○Kenichiro Hoashi1, Akiko Eguchi2, Shinji Mitsuiki1 (1. Kyushu Sangyo University, 2. Leading Labo Co., Ltd.)
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[1P-008]Agrobacterium-mediated transformation: An efficient method for introducing plasmid vectors to fungi

○Kazuya Kiyokawa1,2,3, Hidetoshi Fujii2,4, Shinji Yamamoto3, Kazuki Moriguchi2,3, Minetaka Sugiyama5, Taisuke Hisatomi6, Takashi Yamamoto1,2, Katsunori Suzuki1,2,3 (1. Genome Editing Innov. Center Hiroshima Univ., 2. Grad. Sch. Integ. Sci. for Life, Hiroshima Univ., 3. Grad. Sch. Sci. Hiroshima Univ., 4. KOBAYASHI Pharmaceutical Co., Ltd., 5. Faculty Life Sci. Hiroshima Institute of Technology, 6. Faculty of Life Sci. and Biotechnol. Fukuyama Univ.)
Comment()

[1P-009(1AS-02-02)]Development of L1 Retrotransposon and eccDNA Reporters for Probing cGAS-STING-Mediated Innate Immune Responses

○Herve Dushimyineza1,2, Jiawei Cai3, Tomoichiro Miyoshi4, Makoto T. Hayashi2,5 (1. Graduate School of Biostudies, Kyoto University , 2. IFOM-KU Joint-Research Laboratory, Graduate School of Medicine, Kyoto University , 3. Nutrition & Biomedicine, Graduate School of Science, Technical University of Munich, 4. Laboratory for Retrotransposon Dynamics, RIKEN Center for Integrative Medical Sciences (IMS), 5. Chromosome Instabilities Unit, IFOM ETS, The AIRC Institute of Molecular Oncology)
Comment()

[1P-010]Elucidating the sarcomere repair pathway

○Sakulrat Mankhong1,2, Minchul Kim1,2 (1. Institute of Genetics and of Molecular and Cellular Biology (IGBMC), 2. University of Strasbourg)
Comment()

[1P-011]Re-definition of Species Boundaries in Bacillus subtilis

○Mia Matsumoto1,2, Ruka Takegawa2,3, Nobuaki Kono1,2,4 (1. Faculty of Environment and Information Studies, Keio University , 2. Institute for Advanced Biosciences, Keio University, 3. Faculty of Policy Management, Keio University , 4. Graduate School of Media and Governance, Keio University)
Comment()

[1P-012]Molecular functions of E2f4 on iPS cell generation

○Zezhen Meng1, Takumi Kishimoto1, Koji Hisatake1, Ken Nishimura1 (1. Laboratory of Gene Regulation, Institute of Medicine, University of Tsukuba)
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[1P-013]Interaction analysis of aptamers targeting Tick-Borne Encephalitis Virus E protein

○Tomohiro Shinozaki1, Yuji Fujii2,3, Kentaro Yoshii2, Taiichi Sakamoto1 (1. Chiba institute of technology, 2. Department of Viral Ecology, National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University, 3. Experimental Animal Research Division, National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University)
Comment()

[1P-014]Development of marker recycling technology in the oleaginous yeast Lipomyces starkeyi

○Hiromu Watanabe1, Rikako Sato1, Harutake Yamazaki1, Shibata Masayuki2, Hiroaki Takaku1 (1. Niigata Univ. of Pharmacy and Med. Life Sci., Fac. of Appl. Life Sci., 2. Fuji Oil Co., Ltd.)
Comment()

[1P-015]A mouse model of pregnancy loss caused by a chromosomal inversion involving the HoxD locus

○Katsuki Hirano1, Satoru Iwata2,3,4,5, Shoji Hirotaka7, Manabu Takamatsu6, Miki Nagahara3, Tsuyoshi Miyakawa7, Takashi Iwamoto1,2,3 (1. Department of Biomedical Sciences, Chubu University Graduate School of Life and Sciences, 2. Department of Biomedical, College of Life and Health Science, Chubu University, 3. Center for Education in Laboratory Animal Research, Chubu University, 4. College of Bioscience and Biotechnology, Chubu University, 5. Center for Mathematical Science and Artificial Intelligence, Chubu University, 6. Division of Pathology, The Cancer Institute Japanese Foundation for Cancer Research, 7. Division of Systems Medical Science, Center for Medical Science, Fujita Health University)
Comment()

[1P-016(1PS-04-04)]Development and optimization of gene knock-in technology with the elimination of a large genomic fragment using CRISPR-Cas3 in human cultured cells

○Daiki Nagatomo1,2,3, Yusuke Kojima3, Kazuto Yoshimi4, Tomoji Mashimo4, Akitsu Hotta3, Tetsushi Sakuma2 (1. Grad. Sch. Med., Kyoto Univ., 2. Grad. Sch. Agri., Kyoto Univ., 3. CiRA, Kyoto Univ., 4. Div. Animal Genet., Lab. Animal Res. Fac., Inst. of Med. Sci., Univ. of Tokyo)
Comment()

[1P-017]Development and Evaluation of a Multiplex qPCR Method for Environmental Monitoring of Pollen Allergens

○QIAN ZHANG1, Daisuke Motooka1, Michiko Kaihotsu2, Kazuki Shimasaki2, Shota Nakamura1 (1. The University of Osaka , 2. Daikin Industries Ltd.)
Comment()

[1P-018]Accelerating Nucleic Acid Drug Development Using Deep Learning

○Tomoya Sakuma1,2, Hideyuki Shimizu1,2 (1. Department of AI Systems Medicine, M&D Data Science Center, Institute of Integrated Research, Institute of Science Tokyo, 2. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-019]Effect of Transcription on 5'-tailed duplex’, an artificial nuclease-free gene-editing tool

○Taiki Kato1, Hidehiko Kawai1, Ryotaro Kamitsubo1, Takao Shoji2, Makoto Koizumi2, Hiroyuki Kamiya1 (1. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ., 2. Modality Res. Lab. I, Daiichi Sankyo Co., Ltd.)
Comment()

[1P-020]Analysis of sequence dependence of a 5'-tailed duplex’, an artificial nuclease-free gene-editing tool

○Ryota Kusumoto1, Hidehiko Kawai1, Takao Shoji2, Makoto Koizumi2, Hiroyuki Kamiya1 (1. Hiroshima Univ., 2. Modality Res. Lab. I, Daiichi Sankyo Co., Ltd)
Comment()

[1P-021]Improvement of Gene-Editing Efficiency by Chemical Modifications of TD’, an Artificial Nuclease-Free Gene-Editing Tool

○Kotoe Hori1, Hidehiko Kawai1, Takao Shoji2, Makoto Koizumi2, Hiroyuki Kamiya1 (1. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ., 2. Modality Res. Lab. I, Daiichi Sankyo Co., Ltd.)
Comment()

[1P-022]Recovery and PCR-Based Detection of Airborne Bacteriophage MS2 Using Sprayed PCR Reagents

○Yuga Morita1, Mina Shimada2, Shinji Katsura1,2,3, Masahiko Oshige1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Grad. Sch. of Food&Pop. Health Sci., Gunma Univ., 3. GUCFW)
Comment()

[1P-023]Development of quantification method for emulsion PCR using microfluidic device

○Shunki Kunitake1, Naoya Shimomura2, Masahiko Oshige1,2,3, Shinji Katsura1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Grad. Sch. of Food & Pop. Health Sci., Gunma Univ., 3. GUCFW)
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[1P-025]Characteristics of tardigrades with an edited gene encoding a membrane protein.

○Koyuki Kondo1 (1. Chiba Institute of Technology)
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[1P-026]Structural Basis of Quinoxaline-Acridine Asymmetric Bis-Intercalators That Bi-Target Topoisomerase I and Oncogene Transcription

○Shun-Ching Wang1,2, Ming-Hon Hou1,2 (1. Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan, 2. Doctoral Program in Medical Biotechnology, National Chung Hsing University, Taichung, Taiwan)
Comment()

[1P-027]Detection of Cisplatin-RNA Adducts and Crosslinks by LC-MS/MS

○Po-Cheng Shao1, Yu-An Chang1, Jyun Hu1, JIA-YUAN CHEN2, Yuan-Jhe Chang1, Chiung-Wen Hu2, Mu-Rong Chao1 (1. Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan, 2. Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan)
Comment()

[1P-028]Insight into the Mechanism of de novo Gene Birth in the Cricket Genome

○Sanno Ryuto1, Kazuhiro Satomura2, Yuka Azami1, Shota Hayakawa1, Kazuya Hirata1, Ken Naito3, Takeshi Suzuki4, Kei Yura1,5, Toru Asahi1,6, Kosuke Kataoka6,7 (1. Dept. of Adv. Sci. Eng., Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 2. Dept. of Biosci., Nagahama Inst. of Bio-Sci. and Tech., 3. Res. Ctr. of Gene. Resour., Natl. Agric. and Food Res. Org., 4. Grad. Sch. Bio-App. Sys. Eng., Tokyo Univ. Agric. Tech., 5. Grad. Sch. Hum. Sci., Ochanomizu Univ., 6. Dept. of Comp. Res. Org., Waseda Univ., 7. Grad. Sch. Eng., Tokyo Univ. Agric. Tech.)
Comment()

[1P-029]Analysis of Tiny Introns and the pre-mRNA Splicing Machinery Identified in the Babesia rodhaini Genome

○Aya Zamoto Niikura1, HIroki Takahashi2 (1. JIHS・NIID, 2. Chiba Univ.)
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[1P-030]Application of CRISPRaic Enabling Simultaneous Regulation of Transcription and DNA Cleavage, and Its Expansion to Prime Editing

○Shunichiro Usui1,3, Atsushi Kunii2, Tetsushi Sakuma3 (1. Dept. of Med., Grad. Sch. of Med., Kyoto Univ., 2. Dept. of Mathematical and Life Sci., Grad. Sch. Sci., Hiroshima Univ., 3. Lab. of Genome Editing Breeding, Grad. Sch. of Agr., Kyoto Univ.)
Comment()

[1P-031]Development of gRNA Design Tool Considering Secondary Structure for Novel Genome Editing Technology UCAY

○Nagi Yoshitsugu1, Yasuhiro Moriizumi2, So Makabe2, Yuichi Kobashi2 (1. Tokyo Metropolitan Industrial Technology Research Institute, 2. BEX Co., Ltd.)
Comment()

[1P-032]Development of a Persistent Amplification Method for Trace RNA Using RT-RamDA Method

○Kentaro Mio1,2, Tetsutaro Hayashi2, Mariko Kuse2, Itoshi Nikaido2 (1. Kobe Univ., 2. RIKEN AGIS)
Comment()

[1P-033]Establishment of reporter cell lines to monitor Epithelial-Mesenchymal Transition

○Rin Fukumoto1, Kaya Osanai2, Konoka Nakamura2, Toshihiko Kishimoto2, Kenji Kokura2 (1. Toho Univ. Graduate school, 2. Toho Univ.)
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[1P-034]A Chromosome-Level Genome Assembly and Annotation of the Cultured Hard Clam from Taiwan

○Ching-Huei Huang1, Cheng-Yen Lin2, Po-Cheng Hsu2, San-Tzu Hsieh3, Fu-Shen Tseng1 (1. Fisheries Research Institute,MOA,Taiwan, 2. Institute of Information Science, Academia Sinica, Taiwan, 3. Yuan Ben Wei Food CO., LTD.)
Comment()

[1P-035]End-to-End Genomic Characterization of Mycoplasma pneumoniae from Clinical Throat Swab Specimens

○Cheng-Hao Yang1, Tsung-Hua Wu2,3, Wei-Kang Huang1, Yung-Chieh Wu1, Yen-Tong Chen1, Rou-Yi Li1, Ying-Tsong Chen1,2,4,5 (1. Institute of Genomics and Bioinformatics, National Chung Hsing University, 2. Ph.D. Program in Medical Biotechnology, National Chung Hsing University, 3. Department of Pediatrics, Show Chwan Memorial Hospital, 4. Biotechnology Center, National Chung Hsing University, Taiwan, 5. Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan)
Comment()

[1P-036]Selective Sequencing of Wolbachia from Transinfected Mosquitoes by Adaptive Sampling

○Wei-Kang Huang1, Cheng-Hao Yang1, Yung-Chieh Wu1, Mei-Hsiu Wan1, Wen-Sheng Yeh1, Yen-Tong Chen1, Jian-Chiuan Lee2, Wei-Liang Liu3, Chun-Hong Chen2,3, Ying-Tsong Chen 1,4,5 (1. Institute of Genomics and Bioinformatics, National Chung Hsing University, Taiwan, 2. National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Taiwan, 3. National Mosquito-Borne Diseases Control Research Center, National Health Research Institutes, Taiwan., 4. Biotechnology Center, National Chung Hsing University, Taiwan, 5. Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan)
Comment()

[1P-037]Emergence of Carbapenem (blaNDM-1) and Extensively-Drug Resistance (XDR) Morganella morganii strain isolated from a diarrheal patient in Kolkata, India

○Goutam Chowdhury1,2, Miki Okuno4, Ayumu Ohno2,3, Kei Kitahara2,3, Shin-ichi Miyoshi3, Thandavarayan Ramamurthy1, Yoshitoshi Ogura4, Asish K Mukhopadhyay1 (1. ICMR-National Institute for Research in Bacterial Infection, Kolkata, India, 2. Collaborative Research Centre of Okayama University for Infectious Diseases at ICMR- NIRBI, Kolkata, India, 3. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan, 4. Department of Infectious Medicine, School of Medicine, Kurume University, Fukuoka, Japan)
Comment()

[1P-038(1PS-06-04)]Decoding the molecular logic of rapidly evolving ZAD zinc-finger proteins in Drosophila

○Raku Saito1, Yusuke Umemura1, Shiho Makino1, Takashi Fukaya1 (1. The Univ of Tokyo)
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[1P-039]Trio Genome Analysis of a Color Mutant in the Leopard Coral Grouper (Plectropomus leopardus)

○Susumu Uji1, Yuji Fujikura1, Tomofumi Yamaguchi1, Kaho Miyoshi1 (1. Japan Fisheries Research and Education Agency)
Comment()

[1P-040]TraDIS Reveals Nutrient Acquisition-Dependent Pathogenesis of Edwardsiella tarda

○Kohei Yamazaki1, Takuya Yamaguchi1, Yuichi Yokoyama1, Yuka Tonosaki1, Kursanbaeva Klara1,5, Daisuke Motooka2, Yukihiro Akeda3,2,4, Takashige Kashimoto1 (1. Vet Public Health, Kitasato Univ., 2. RIMD, Osaka Univ, 3. Department of Bacteriology I, NIID, 4. Med, Osaka Univ, 5. Kyrgyz Research Institute of Veterinary Science named after A. Duisheev)
Comment()

[1P-041]A Multi-Omics Variational Autoencoder for Predicting Mortality Risk from SNP and DNA Methylation Profiles

○GwangWon Cho1,2,3, Karthikeyan A Vijayakumar1,2 (1. Department of Biological Science, College of Natural Sciences, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 501-759, Korea, 2. The Basic Science Institute of Chosun University, Chosun University, Gwangju 61452, Korea, 3. Department of Integrative Biological Science, BK21 FOUR Education Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju 61452, Korea)
Comment()

[1P-042]The human PTGR1 gene expression is controlled by TE-derived potential Z-DNA transition sequence interacting with miR-6867-5p

○DuHyeong Lee Lee1, WooHyun Bae1, EunGyung Park1, YunJu Lee1, Heui-Soo Kim1 (1. Pusan national university)
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[1P-043]Benome assembly of the white trevally (Pseudo caranx dentex) and development of a PCR sex genotyping system of the fish.

○Yasuo Agawa1, Yuta Inoue1, Naoki Taniyama1, Yoshifumi Sawada1, Hirakawa Hideki2,3, Kenta Shirasawa2, Sachiko Isobe2,4 (1. Aquaculture Research Institute, Kindai University, 2. KAZUSA DNA Research Institute, 3. Kyushu University, 4. The University of Tokyo)
Comment()

[1P-044]Identification of a dominant genic male sterility gene derived from rice cultivar Lebed.

○Kodai Takahashi1, Yusei Fujita1, Masanori Sawamura1, Yuko Iwai1, Keisuke Igarashi1, Tomohiko Kazama2,1, Ryouhei Morita3, Hiroyuki Ichida3, Tomoko Abe3, Kinya Toriyama1 (1. Grad. Sch. Agri Sci., Tohoku Univ., 2. Fac.Agri.,Kyushu Univ., 3. RIKEN, Nishina Cent.)
Comment()

[1P-045]Developing Efficient Metadata Extraction and Curation Methods for Gene Expression Databases Using Large Language Models

○MITSUO SHINTANI1, Daniel Andrade2, Hidemasa Bono1 (1. Grad. Sch. Int. Sci., Hiroshima Univ., 2. Grad. Sch. Adv. Sci., Hiroshima Univ.)
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[1P-046]Coordinated Reorganization of the Mitochondrial Genome Variant Network Induced by Ultraviolet Radiation

○Sachiko Nitta1, Kohta Nakamura1, Naoyuki Matsumoto1, Yasunari Sato2, Masao Hashimoto2, Ayaka Funakoshi2, Yuji Mochizuki2, Osamu Minowa1, Kenji Watanabe1, Yasuo Miyoshi3, Yasushi Okazaki1, Hiroki Nagase1 (1. Juntendo University, 2. Rohto Pharmaceutical, 3. Hyogo Medical College Hospital)
Comment()

[1P-047]Long Terminal Repeats of HERV Families Derived Potential Z-DNA Sequence Provide Alternative Promoter in Human Functional Genes

○Heui-Soo Kim1, DuHyeong Lee1, WooHyun Bae1, YunJu Lee1, EunGyung Park1 (1. Pusan national university)
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[1P-048]High-quality draft genome sequence of the golden leaf beetle Aspidimorpha transparipennis (Motschulsky, 1860), a member of the Cassidinae subfamily

○Shintaro Inoue1, Kengo Noma2, Takahito Watanabe1, Sumihare Noji3, Taro Mito1 (1. BIRC, Tokushima university, 2. Bioresource sciences, Nihon university, 3. Tokushima university)
Comment()

[1P-049]Comprehensive identification of Human-specific de novo gene

○RIntaro Amano1, Ikuo Suzuki1, Kazuo Emoto1,2 (1. University of Tokyo, 2. International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo)
Comment()

[1P-050]Enhancing CRISPR-Cpf1 Precision in Corynebacterium glutamicum Through Host System Modulation

○Muhammad Shoaib Ashraf1, Xinyu Yu2, Chong Zhang2, Shihab uddin1 (1. King fahad University of Petroleum and Minerals Saudi Arabia, 2. Tshinghua university)
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[1P-051]Formation of AT skew in the Bombyx mori nucleopolyhedrovirus (BmNPV) genome by DNA replication and evolutionary selection

○Tsuneyuki Tatsuke1 (1. National Agriculture and Food Research Organization)
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[1P-052]Genomic Infrastructure with the Japonica ArrayTM in the Tohoku Medical Megabank Project

○Mika Sakurai-Yageta1, Sachiyo Sugimoto1, Masae Kimura1, Chinatsu Gocho1, Akihito Otsuki1, Akira Narita1, Satoshi Makino1, Takamitsu Funayama1, Yuichi Aoki1, Hisaaki Kudo1, Kazuki Kumada1, Gen Tamiya1, Masayuki Yamamoto1, Kengo Kinosihta1 (1. Tohoku University)
Comment()

[1P-053]Effect of LLPS inhibition on radiation-induced genomic mutations

○Kasumi Kawamura1, Keiji Suzuki1 (1. Nagasaki University)
Comment()

[1P-054]Functional analysis of lepidopteran insect-specific genes involved in germ cells

○Yusuke Fujii1, Hiroaki Mon1, Kohei Kakino2, Jae Man Lee1, Takahiro Kusakabe1 (1. Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu Univ., 2. Faculty of Economics, Kyushu Univ.)
Comment()

[1P-055]Multi-Omics Single-Cell Profiling Reveals Glycomic and Transcriptomic Features of Pancreatic Cancer

○Dinh Xuan Tuan Anh1,2, Sunanda keisham2, Arun Burramsetty2, Lalhaba Oinam2, Koichiro Kumano2, Akihiro Kuno1, Osamu Shimomura1, Tatsuya Oda1, Hiroaki Tateno1,2 (1. University of Tsukuba, 2. National Institute of Advanced Industrial Science and Technology (AIST))
Comment()

[1P-056]Mechanisms of re-replication and checkpoint activation induced by dysregulation of Cdt1

○Tsumugi Mitsuo1, Yasunori Noguchi1, Youko Katsuki1, Miyako Shiraishi1, Masatoshi Fujita1 (1. Kyushu Univ.)
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[1P-057]Mechanism of replication initiation of the cyanobacterial large plasmid pSYSX via Small RNA and a novel replication factor CyRepX.

○Satoru Watanabe Watanabe1, Minori Sakata1, Kazuma Ohdate1, Kaori Nimura-Matsune1, Wolfgang Hess2 (1. Tokyo Univ. Agric., 2. Freiburg Univ.)
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[1P-058]Elucidation of the Mechanism by which Histone Acetyltransferase HBO1 promotes DNA Replication Origin Licensing in Human Cells

○Yuki Yamamoto1, Miyako Shiraishi1, Yasunori Noguchi1, Yoko Katsuki1, Torahiko Higashi1, Masatoshi Fujita1 (1. Department of Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Kyushu University)
Comment()

[1P-059]Analysis of the mechanism maintaining the stability of human ribosomal RNA repeat genes

○Masaki Kobayashi1,2, Hori Yutaro2, Takehiko Kobayashi1,2 (1. The university of tokyo, 2. IQB)
Comment()

[1P-060]SUMOylation pathway directs SLX4-XPF to replication forks stalled by the nucleoprotein complexes formed at long repetitive DNA.

○Soki Haruta1, Takuma Okano1, Yuki Matsumura1, Jyunpei Fujii1, Kazuma Yoshida1, Katsuki Yoko1, Miyako Shiraishi1, Yasunori Noguchi1, Masatoshi Fujita1 (1. Dept. Celullar Biochem., Grad. sch. Pharm. sci., Kyushu Univ.)
Comment()

[1P-061]FEN1 mutated cells exhibit hypersensitivity to CHK1 inhibitor

○Yuto Saito1, Ratul Md Rahman1, Ryotaro Kawasumi1, Kouji Hirota1 (1. Tokyo Metropolitan University)
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[1P-062(1MS-04-04)]The genetic interaction between Polη and Polζ differs between “on the fly” TLS and TLS in “post replicative gap filling”

○Mone Okuda1, Minori Fujii1, Ryotaro Kawasumi1, Kouji Hirota1 (1. Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University)
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[1P-063]Automated analysis of DNA fibers using deep learning models

○Takuma Yamato1, Kiyoshi Nishikawa1, Kan Okubo1, Takuya Abe2 (1. Tokyo Metropolitan Univ., 2. Tohoku Medical and Pharmaceutical Univ.)
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[1P-064]Cell-free manipulation technique for long circular DNA using AGM (Agarose Gel Microcapsule)

○Togo Asami1, Masayuki Su’etsugu1 (1. Rikkyo University)
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[1P-065]The molecular role of NIPBL in DNA repair and its implications for CdLS

○Aya Tsukada1, William Mango Jandi1, Kaima Tsukada2, Andrew Nicholas Blackford2, Fena Ochs1 (1. Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, 2. Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark)
Comment()

[1P-066(1PS-04-02)]Activation of non-canonical DSB repair pathways acceralate CRISPR-Cas9 mediated HDR

○Shogo Yamamoto1, Shoma Takashima2, Daisuke Motooka3, Daisuke Tachibana1, Junpei Yamamoto2, Shigenori Iwai2, Keiichiro Suzuki1,2,4 (1. Grad. Front. Bio., UOsaka, 2. Grad. Eng. Sci., UOsaka, 3. Res. Ins. Micro. Dis., UOsaka, 4. Ins. Ad. Co-cre. Stu., UOsaka)
Comment()

[1P-067]Effect of single nucleotide polymorphisms on the activity of bone marrow stromal cell antigen 1

○Kozaburo Usui1, Takashi Nakagawa1, Keisuke Yaku1 (1. Toyama Univ.)
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[1P-068]DNA-PKcs facilitates NHEJ in vitro

○Shingo Fujii1, Mauro Modesti1 (1. Cancer Research Center of Marseille, CNRS UMR7258)
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[1P-069]Optimization of the basic form of reverse prime editing (inverse prime editing)

○Toshinori Hyodo1, Md Towhid Ahmed Shihan1, Muhammad Nazmul Hasan1, Mrityunjoy Biswas1, Lam Quang Vu1,2, Nushrat Jahan1, Yuko Mihara1, Sivasundaram Karnan1, Akinobu Ota3, Shinobu Tsuzuki1, Yoshitaka Hosokawa1, Hiroyuki Konishi1 (1. Aichi Medical Univ., Sch. of Med., Dept. of Biochem., 2. Aichi Medical Univ., Sch. of Med., Div. of Hematology, 3. Kinjo Gakuin Univ., Dept. of Food and Nutritional Env.)
Comment()

[1P-070]Detailed characterization of tandem paired nicking (TPN) demonstrates rare genomic deletions of varying sizes during TPN-based targeted knock-in

○Md Towhid Ahmed Shihan1, Toshinori Hyodo1, Takeshi Fujino6, Md. Lutfur Rahman1, Muhammad Nazmul Hasan1, Mrityunjoy Biswas1, Lam Quang Vu1,3, Nushrat Jahan1, Yuko Mihara1, Sivasundaram Karnan1, Akinobu Ota1,2, Shinobu Tsuzuki1, Atsushi Toyoda4,5, Yoshitaka Hosokawa1, Masahiro Kasahara6, Hiroyuki Konishi1 (1. Aichi Med. Univ., Sch. of Med., Dept. of Biochem., 2. Kinjo Gakuin Univ., Dept. of FNE. , 3. Aichi Med. Univ., Sch. of Med., Div of Heme., Dept of Intern. Med., 4. National inst. of Genet., Dept of Genom. and Evol. Biol., 5. National inst. of Genet., Adv. Genom. Cent., 6. Univ. of Tokyo., Graduate Sch. of Front. Sci.)
Comment()

[1P-071]Accurate genome editing through cell cycle-dependent activation of a Cas9 mutant obtained by selection

○Daisuke Matsumoto1,2,3, Komari Kubota2, Yu Sato4, Tomoko Kato1, Kiyomi Nigorikawa2,3, Yuichiro Miyaoka1, Wataru Nomura2,3 (1. Reg. Med. Proj., TMiMS, 2. Sch. Pharm. Sci., Hiroshima Univ., 3. Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 4. Res. Cent. Thermotolerant Microbial Resour., Yamaguchi Univ.)
Comment()

[1P-072]Enhancing HDR-Mediated Knock-In Efficiency via Transient Inhibition of the SSBR Pathway in Fish

○Takashi Yamanaka1, Yoshitaka Tanaka2, Satoshi Ansai2, Masato Kinoshita1 (1. Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, 2. Ushimado Marine Institute, Okayama University)
Comment()

[1P-073]DNA damages associated with genomic instability, arisen after ionizing radiation and ultraviolet light exposures

○Yusuke Matsuno1, Rika Matsuo1,2, Naoki Akiba1,3, Ken-ichi Yoshioka1 (1. Lab. Genome Stability Maintenance, NCCRI, 2. Advanced Cancer Translational Research Institute, Showa Medical University, 3. Department of Biological Science and Technology, Tokyo University of Science)
Comment()

[1P-074]Cryo-EM Structural Analysis of Chromatin Remodeling during Homologous Recombination Progression

○Takuro Shioi1,2, Suguru Hatazawa1, Yuki Kobayashi1, Mitsuo Ogasawara1, Yoshimasa Takizawa1, Hitoshi Kurumizaka1,2 (1. Inst. for Quantitative Biosciences, The Univ. of Tokyo, 2. Dept. of Biological Sciences, Grad. School of Sci., The Univ. of Tokyo)
Comment()

[1P-075]Identification of G-quadruplex binding domain of ATRX and their functional roles

○Yukiko Kojima1, Koichi Hattori1, Manami Kobori1, Masahiro Nakajima1, Hisao Masai2, Mahito Sadaie1 (1. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci., 2. TMIMS)
Comment()

[1P-076]Towards Establishing a Universal and Efficient CRISPR-Cas9 Platform for Spider Genome Editing

○Koh Nakagawa1,2,3, Yasuko Akiyama-Oda1,4, Yuta Sakae5, Masataka G Suzuki6, Shuji Shigenobu 7, Nobuaki Kono2,3,8, Hiroki Oda1,9 (1. JT Biohistory Research Hall (BRH), 2. Grad. Sch. of Media & Gov., Keio Univ., 3. Inst. for Adv. Biosci., Keio Univ. (IAB), 4. Osaka Med. & Pharm. Univ., 5. Tokyo Univ. of Sci., 6. Grad. Sch. of Frontier Sci., Univ. of Tokyo, 7. Natl. Inst. of Basic Biol. (NIBB), 8. Fac. of Env. & Info. Stud., Keio Univ., 9. Grad. Sch. of Sci., Osaka Univ.)
Comment()

[1P-077]A lactic acid bacteria platform for biosynthesis of plant natural products

○Takumi Itabashi1, Shunsuke Takahashi2, Toshiki Saito1, Koko Takata1 (1. TDU Dept. of Sci, 2. TDU Univ.)
Comment()

[1P-079(1MS-03-05)]Physiological effects of different types DNA modifications induced by an acrylamide metabolite

○Jun-ichi Akagi1, Masayuki Yokoi2, Yumi Miyake3, Kohei Matsushita1, Kaoru Sugasawa2, Shigenori Iwai2,4,5, Takeshi Toyoda1 (1. Div. Pathology, Natl. Inst. Health Sci., 2. Biosignal Res. Ctr., Kobe Univ., 3. Forefront Res. Ctr., Grad. Sch. of Sci., Osaka Univ., 4. Grad. Sch. of Eng. Sci., Osaka Univ., 5. Frontier Science, Konan Univ.)
Comment()

[1P-080]Structural Analysis of the RAD52–Nucleosome Complex by Cryo-Electron Microscopy

○Chiaki Kinoshita1,2, Takuro Shioi1, Yoshimasa Takizawa1, Hitoshi Kurumizaka1, Wataru Kagawa2 (1. Inst. Quant. Biosci., Univ. of Tokyo, 2. Dept. of Chem., Grad. Sch. Sci. Eng., Meisei Univ.)
Comment()

[1P-081]PARP1 Promotes Cellular Tolerance to hmdU by Maintaining Fork Progression and Nascent DNA Integrity

○Rubaiat E Tabassum1, Kouji Hirota1, Ryotaro Kawasumi1 (1. Tokyo Metropolitan University)
Comment()

[1P-082]Regulation of meiotic pro-crossover factor assembly in the presence of mismatches using budding yeast hybrid zygotes

○Rina Ishizaki1, Ting-Fang Wang2, Miki Shinohara1,3 (1. Graduate School of Agriculture, Kinki University, 2. Institute of Molecular Biology, Academia Sinica, 3. Agricultural Technology and Innovation Research Institute, Kinki University)
Comment()

[1P-083]Identification and Functional Analysis of Novel RG/RGG Motif-Containing Proteins Involved in the DNA Double-Strand Break Response and Repair

○Miko Urano1, Ryotaro Nishi1 (1. Mol. Biol. Lab., Grad. Sch. Bionics, Tokyo Univ. Tech.)
Comment()

[1P-084]Mek1-mediated Suppression of Rad53 and Regulation of Inter-homolog Bias During Meiotic Recombination

○Sayaka Kurihara1, Takuya Suzuki1, miki Shinohara1,2 (1. Advanced Bioscience, Graduate School of Agriculture, Kindai University, 2. Agricultural Technology and Innovation Research Institute, Kindai University)
Comment()

[1P-085]Binding of APOBEC3B to R-loop caused by DNA damage

○Yohei Saito1, Kosuke Takahashi1, Rinyuu Noguchi1, Kano Motoori1, Yumi Yamamoto1, Fumihiko Yamamoto1 (1. Tohoku Med. and Pharm. Univ.)
Comment()

[1P-087]Re-evaluation of the Pathogenicity of EYS Gene Variants in Japanese Retinitis Pigmentosa Using Targeted Capture-Based Next-Generation Sequencing

○Aya Takeishi1, Tadashi Imanishi1 (1. Tokai University, Graduate School of Medicine.)
Comment()

[1P-088]Mechanistic analysis of enhanced alkylating agent sensitivity induced by ATAD5 deficiency

○Ryosuke FUJIKANE1,2, Kano Tokui1, Masumi Hidaka1,2 (1. Dept. Physiol. Sci. and Mol. Biol., Fukuoka Dental College, 2. Oral Med. Res. Cent., Fukuoka Detenal College)
Comment()

[1P-089]H3K36 histone methyltransferase Set2 interacts with Fanconi anemia factors to repair alkylation DNA damages

○Ee Sin CHEN1,2, Cheryl Jian-Hui Ng1, Raechell Raechell1, Kim Kiat Lim1 (1. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 2. NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore)
Comment()

[1P-090]Paf1 Counteracts Transcriptional Arrest and rNMP Overload to Maintain rDNA Stability During RNAP1 Elongation

○zhong zijun1,2, Masaki Yokoyama2,1, Takehiko Kobayashi1,2 (1. Department of Biological Sciences. Graduate School of Science. The University of Tokyo, 2. Institute for Quantitative Biosciences. The University of Tokyo)
Comment()

[1P-091]Opposing DNA damage (ODD) resulted in DSBs by DNA repair.

○Takahito Moriwaki1 (1. Institute for Environmental Sciences)
Comment()

[1P-092]Development of highly efficient genome editing platform for mammalian cells and plants using Type I-D CRISPR-Cas, TiD-X

○Yuriko Osakabe1, Naoki Wada2, Shota Muromoto1, Kugo Goto1, Satoshi Kidokoro1, Keishi Osakabe2 (1. Institute of Science Tokyo, 2. Tokushima Univ.)
Comment()

[1P-093]BRC repeat 8 of BRCA2 overexpression–induced stabilization of the homologous recombination enzyme RAD51: a possible regulation of RAD51 degradation via the ubiquitin–proteasome system

○Zida Zhu1, Taisuke Kitano1, Koichi Orino1, Masami Morimatsu2, Yasunaga Yoshikawa1 (1. Kitasato Univ., 2. Hokkaido Univ.)
Comment()

[1P-094]Analysis of the genetic relationship between pof1 and nrd1 in Rqh1-deficient fission yeast

○Beibei Jiang1, Subaru Imada2, Masaru Ueno1,2 (1. Hiroshima Univ.・Grad. Sch. Integrated Sci. Life, 2. Hiroshima Univ.・Sch. Eng.)
Comment()

[1P-095]Epigenetic mechanisms characterizing gene expression changes during disuse muscle atrophy

○Junya Shimizu1,2,3, Fuminori Kawano2 (1. Institute of Science Tokyo, 2. Matsumoto University, 3. Japan Society for the Promotion of Science)
Comment()

[1P-096]Exploration of Age-dependent Epigenetic Regulation in Cardiac Resident Macrophages

○GENKI OHNO1, SHION NAGASAWA1, HYEREE KIM1,2, FUJIMI KUDO1, KATSUTOSHI IMAMURA1, YUICHIRO NAKATA1, ICHIRO MANABE1 (1. Dep. of Systems Medicine, Grad. Sch. of Med, Chiba Univ., 2. Dep. of Molecular Cardiovascular Pharmacology, Grad. Sch. of Pharm. Sci, Chiba Univ.)
Comment()

[1P-097]Decoding Spermatogonial Stem Cell Differentiation through Epigenomic Analysis

○Shin-ichi Tomizawa1, Kazushige Kuroha1, Ivana Dockal1, Michio Ono1, Stephen Clark2, Gavin Kelsey2, Kazuyuki Ohbo1 (1. Yokohama City Univ., 2. Babraham Inst.)
Comment()

[1P-098]Epigenetic Regulation of Fatty Acid Synthesis by Id4

○Koji Kinoshita1,2, Hayashi Yoshikazu1,3,4, Takahashi Ichiro2, Masato Hirata4, Jimi Eijiro5,1, Yasukochi Tomoyo1 (1. Kyushu University OBT Reserch Center, 2. Kyushu University Othodontics, 3. Fukuoka Dental University Functional Structure Science, 4. Fukuoka Dental University Oral Medicine Reserch Center, 5. Kyushu University Oral Cell Engineering)
Comment()

[1P-099]Structural and biochemical analyses of chromatin regulation by lamin B receptor

○Manato Iizuka1,2, Naoki Horikoshi1, Hitoshi Kurumizaka1,2 (1. Institute for Quantitative Biosciences, Laboratory of Chromatin Structure and Function , 2. Department of Biological Sciences, Graduate School of Science, The University of Tokyo)
Comment()

[1P-100]Estimation of germ intercellular bridge (ICB) fragmentation regulator by H3K27me3 ChIP-seq

○Yusuke Sakurai Sakurai1, Sakurako Shima1, Tokuko Iwamori2,3, Naoki Iwamori2 (1. Kyushu university, 2. Kyushu Univ. Faculty of Agriculture, 3. Nakamura Gakuen Univ.)
Comment()

[1P-101]Ensemble Stacking Model for Predicting All-Cause Mortality Risk using DNA methylation data

○Yugan Gogul Muthukumar3, Karthikeyan A Vijayakumar1,2, Gwang-Won Cho1,2,3 (1. Department of Biological Science, College of Natural Sciences, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 501-759, Korea., 2. The Basic Science Institute of Chosun University, Chosun University, Gwangju 61452, Korea. , 3. Department of Integrative Biological Science, BK21 FOUR Education Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju 61452, Korea.)
Comment()

[1P-103]High-resolution cryo-EM structure of nucleosomes formed in E. coli cells

○Cheng-Han Ho1, Yuki Kobayashi1, Mitsuo Ogasawara1, Yoshimasa Takizawa1, Hitoshi Kurumizaka1 (1. IQB, Univ. Tokyo)
Comment()

[1P-104]Analysis of transcriptional regulation of nucleosomes by centromere-specific proteins.

○Takumi Oishi1,2, Risa Fujita1, Yoshimasa Takizawa1, Suguru Hatazawa1, Tomoya Kujirai1,3, Haruhiko Ehara3, Shun-ichi Sekine3, Leonid Velikovsky4, Daniele Fachinetti4, Hitoshi Kurumizaka1,2,3 (1. IQB, The Univ. of Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., The Univ. of Tokyo, 3. RIKEN, BDR, 4. Institut Curie, Cell Biol. and Cancer)
Comment()

[1P-105]Identification of human genomic sequences with the potential to form atypical nucleosomes by cryo-EM

○Eri Ito1,2, Cheng-Han Ho1, Yuki Kobayashi1, Mitsuo Ogasawara1, Yasuyuki Ohkawa3, Yoshimasa Takizawa1, Hitoshi Kurumizaka1,2 (1. IQB, Univ. Tokyo, 2. Grad. Sch. of Sci., Univ. Tokyo, 3. MIB, Kyushu Univ.)
Comment()

[1P-106]Genome-wide profiling of insulin-degrading enzyme target genes reveals its role in biological processes

○Yoshinori Hiraoka1, Franziska Greulich2, Benjamin Stickland2, Nina Henriette Uhlenhaut2 (1. Kobe Gakuin University, 2. Technical University of Munich)
Comment()

[1P-107]Comprehensive analysis of target genes for distal silencer

○Yasunori Uebayashi1, Hitoshi Ohtani1 (1. Nagoya university, Agriculture)
Comment()

[1P-108(1PS-09-03)]A multilayered regulatory system that tunes condensin II for mitotic chromosome assembly

○Makoto Michael Yoshida1, Kazuhisa Kinoshita2, Yuuki Aizawa2, Tatsuya Hirano2, Tomoko Nishiyama1 (1. Kyoto University, 2. RIKEN)
Comment()

[1P-109]Novel histone modification O-GlcNAcylation of H4Thr71 is localized to constitutive heterochromatin regions.

○Koji Hayakawa1, Mitsuko Hirosawa2, Daisuke Nara2, Nobuyuki Fujiwara3, Kunio Shiota2, Satoshi Tanaka2 (1. Okayama Univ. of Sci., Fac. of Vet Med, Lab. of Genet., 2. Univ. of Tokyo, Dep. of ARS, 3. Okayama Univ. of Sci., Fac. of Vet Med, Lab. of Drug.)
Comment()

[1P-110]Mechanism of retrotransposon reactivation induced by loss-of-function mutation in TET2

○Yuta Akahane1, Hirofumi Aso2,3, Mamiko Sakata-Yanagimoto4, Kohsuke Kato5, Atsushi Kawaguchi5 (1. Graduate School of Comprehensive Human Sciences, University of Tsukuba, 2. Department of Medicine Solna, Karolinska Institutet, 3. Institute of Integrated Research, Institute of Science Tokyo, 4. Department of Hematology, Institute of Medicine, University of Tsukuba, 5. Department of Infection Biology, Institute of Medicine, University of Tsukuba)
Comment()

[1P-111]AGO1b Regulates sRNA Loci, Methylation, and Gene Expression to Control Anther Development in Rice

○Zein Eddin Bader1, Hinako Tamotsu2, Ngoc Tu Le2, Reina Komiya1,2 (1. Reproduction System RIKEN ECL Research Team, RIKEN Center for Sustainable Resource Science, 2. Science and Technology Group, Okinawa Institute of Science and Technology Graduate University (OIST))
Comment()

[1P-112]Effects of aclarubicin on the nuclear mobility of DNA topoisomerase IIβ (Top2B)

○Ken-ichi Yano1, Keiko Morotomi-Yano1, Shinji Kawano2 (1. Institute of Industrial Nanomaterials, Kumamoto University, 2. Faculty of Life Science, Department of Bioscience, Okayama University of Science)
Comment()

[1P-113(1AS-05-05)]Transgenerational Inheritance of Epigenetic Memory in Mammals

○Yuta Takahashi1 (1. Kumamoto University)
Comment()

[1P-114(1MS-03-08)]Relationship between neurodegenerative diseases and FUS as a novel m6A reader

○Ryoma YONEDA1, Naomi UEDA1, Riki KUROKAWA1 (1. Dept. of Biol. Sci., Faculty of Med., Saitama Med. Univ.)
Comment()

[1P-115]Expression control mechanism of heterochromatin regions under osmotic stress

○Mayumi Inami1, Takuma Yokosawa1, Masaya Oki1 (1. University of Fukui)
Comment()

[1P-116]Mechanistic Elucidation of Epigenetic Regulation of Angiogenesis in Ischemic Retinopathy

○Hotaka Morimoto1, Akinori Tokunaga2, Yoshihiro Takamura3,4, Masaru Inatani3,4, Takayoshi Suzuki5, Masaya Oki4,6 (1. Dept. of Ind. Innov. Eng., Grad. Sch. of Eng., Univ. of Fukui, 2. Div. of Lab. Animal Res., Life Sci. Res. Center, Univ. of Fukui, 3. Dept. of Ophthalmol., Sensory & Locomotor Med., Div. of Med., Fac. of Med. Sci., Univ. of Fukui, 4. Life Sci. Innov. Center, Univ. of Fukui, 5. Dept. of Complex Mol. Chem., ISIR, Osaka Univ., 6. Div. of Appl. Chem. & Biotech., Fac. of Eng., Univ. of Fukui)
Comment()

[1P-118]Effects of CDE mutations on the organization and function of the centromeric chromatin in S. cerevisiae

○Kota Tosaka1, Nagisa Ochiai1, Wataru Kagawa1, Akio Yanagida2, Hiroaki Kato3, Mitsuhiro Shimizu1 (1. Grad. Sch. of Sci. and Eng., Meisei Univ., 2. Sch. of Pharm., Tokyo Univ. of Pharm and Life Sci., 3. Shimane Univ. Sch. of Med.)
Comment()

[1P-119]The mechanism of gene expression mediated by estrogen receptors in medaka liver

○Sayaka Enomoto1 (1. Graduate School of Tokyo University of Science)
Comment()

[1P-120]Isolation of novel regulatory factors of ABA Biosynthesis and their functional analysis under salt stress in Arabidopsis thaliana

○Tomoki Kuribayashi1, Hikaru Sato1,2, Satoru Fujimoto3, Kazuo Shinozaki2, Sachihiro Matsunaga1 (1. Dept. of Integr. Biosci., Univ. Tokyo, 2. RIKEN CSRS, 3. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci.)
Comment()

[1P-121(1AS-15-07)]A common retinal cis-regulatory code underlying genomic sequence diversity

○Yohei Ogawa1,2, Yu Liu2, Joseph C. Corbo2 (1. National Institute of Genetics, 2. Washington University School of Medicine)
Comment()

[1P-122]Generation of Igf2-EGFP knock-in mice for visualizing cells with loss of imprinting at Igf2-H19 locus

○Satoshi Hara1, Fumikazu matsuhisa2, Shuji Kitajima2, Musashi Ichimaru1, Hidenobu Soejima1 (1. Div. Mol. Genet., Saga Univ., 2. Anal. Res. Cen. for Exp. Sci., Saga Univ.)
Comment()

[1P-123]Role of Testis-specific H2B Variant H2B.W2 in Fertility and Telomere Regulation During Spermatogenesis

○Tingyu Jin1, April T. T. Nguyen1, Matthew Y H Pang1, Rui Huang1, Xinpeng Bai1, Yan Yan1, Toyotaka Ishibashi1,2 (1. Division of Life Science, The Hong Kong University of Science and Technology, 2. Guangzhou HKUST Fok Ying Tung Research Institute)
Comment()

[1P-124]The histone onco-mutation H2BE113K enhances chromatin condensation, with implications on DNA damage repair

○Long Wai Tsui1, Matthew Yu Hin Pang1, Tingyu Jin1, Yue Liu1, Wai Hei Shek1, Toyotaka Ishibashi1 (1. Hong Kong University of Science and Technology)
Comment()

[1P-125]Analysis of the significance of transcription-coupled H3K4me1 from the perspective of stress response

○Rino Koizumi1, Soichi Inagaki1 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo)
Comment()

[1P-126]Elucidation of the molecular basis for rejuvenation of senescent cells through reprogramming

○Yuta Moriguchi1, Yasuhiro Nakano2,1, Soichirou Kumamoto1, Tomoaki Hishida3, Yoshikazu Johmura1,2 (1. Cancer Research Institute of Kanazawa University, 2. Institute for Frontier Science Initiative, 3. School of Pharmacy, Wakayama Medical University)
Comment()

[1P-127]Expression changes of G9a and GLP during EMT/MET progression and analysis of H3K9 modifications

○Nozomi Hamano1, Miyu Eguchi2, Haruka Kawashima3, Toshihiko Kishimoto2, Kenji Kokura2 (1. Dept.of Biomol.Sci.,Grad.Sci.,TOHO Univ, 2. Dept.of Biomol.Sci.,Facul.Sci.,TOHO Univ, 3. Dept.of Comprehensive Human Sci.,Grad.Sci.,Tsukuba Univ)
Comment()

[1P-128]RNA-seq analysis of differentially expressed genes in phosphorylation-site mutants of Brg1, a core subunit of the SWI/SNF complex

○Ayuko Kimura1, Jun Nakabayashi2, Osamu Ohara3, Yayoi Kimura4 (1. Graduate School of Health Sciences, Gunma Paz University, 2. Department of Mathematics, Institute of Science Tokyo , 3. Kazusa DNA Research Institute, 4. Advanced Medical Research Center, Yokohama City University)
Comment()

[1P-129]HUSH complex modulates de-repression of transposable elements during antiviral response

○Shota Azuma1,2, Yuka W Iwasaki1 (1. RIKEN Center for Integrative Medical Sciences, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., The Univ. of Tokyo)
Comment()

[1P-130]Loss of Utx promotes tumor invasion and metastasis in a breast cancer mouse model

○Akiyoshi Komuro1, Ryoichi Sugisawa1, Takeshi Ueda1, Naohumi Tomimoto1, Hitoshi Okada1 (1. Kindai Univ.)
Comment()

[1P-131]H3K9me2-mediated regulation of mouse zygotic genome activation

○Ryo Maeda1, Shunsuke Kuroki1, Azusa Inoue2, Makoto Tachibana1 (1. The University of Osaka, 2. RIKEN Center for Integrative Medical Sciences)
Comment()

[1P-132]Polycomb repressive complexes (PRC)1 safegurads chromatin replication in the vicinity of the fork

○Junichiro Takano1, Shinsuke Ito1, Haruhiko Koseki1 (1. RIKEN)
Comment()

[1P-133]Formation of H3K27me3 Broad Domains during Neuronal Differentiation and Maturation Contributes to a Suppression of Non-Neuronal Lineage Genes

○Chika Ichihara1, Natsumi Yamada1, Hiroki Sugishita1, Yukiko Gotoh1,2 (1. The University of Tokyo, Department of Pharmaceutical Sciences, 2. WPI-IRCN)
Comment()

[1P-134(1AS-15-03)]Polymeric mechanism of positive feedback between promoter and enhancer activities

○Tetsuya Yamamoto1, Koji Kawasaki2, Takashi Fukaya2 (1. Hokkaido Univ. , 2. Tokyo Univ.)
Comment()

[1P-135]Analysis of coactivators for the transcription factor HSF1 identified by TurboID

○Ryosuke Takii1, Masaki Matsumoto2, Akanksha Pandey1, Mitsuaki Fujimoto1, Akira Nakai1 (1. Dept. of Biochem. & Mol. Biol., Grad. Sch. of Med., Yamaguchi Univ, 2. Dept. of Omics & Systems Biol., Grad. Sch. of Med. & Dent. Sci., Niigata Univ.)
Comment()

[1P-136]Transcription elongation factor (Elongin) regulates cold tolerance in C. elegans by acting on a specific neuron in the tail.

○Sho Yabuuchi1,2, Hiroaki Teranishi1,2, Toshihiro Iseki1,2, Natsune Takagaki1,2, Yohei Minakuchi3, Atsushi Toyoda3, Akane Ohta1,2, Kuhara Atsushi1,2,4 (1. Dept.Biol. Grad. Sch. Sci. Konan Univ, 2. Inst. of Integral NeuroBiol. Konan Univ, 3. National Institute of Genetics, Japan, 4. PRIME AMED)
Comment()

[1P-137]Characterization of Transcription Terminators in Escherichia coli

○Yuka Baba1, Rinji Akada2, Mikiko Nakamura3 (1. Shinshu Univ., 2. Yamaguchi Univ., 3. Shinshu Univ. RCAST)
Comment()

[1P-138(1PS-09-05)]Cohesin promotes initiation and restrains pause release in RNA Pol II transcription

○Shoin Tei1, Masashige Bando1, Katsuhiko Shirahige1 (1. The Univeristy of Tokyo)
Comment()

[1P-140]Synchrotron Imaging and Transcriptomics Reveal 3D Remodeling and Molecular Pathogenesis of Aortic Dissection in Fbn1G234D/G234D Novel Mutant Mice

○MD AL AMIN SHEIKH SHEIKH1,2, Kenichi Kimura1, Eri Motoyama1, Violette Deleeuw3, Sachiko Kanki4, Keiichi Asano1, Ryutaro Ishii1,5, Patrick Sips3, Julie De Backer6, Lynn Y Sakai7, Haruka Ozaki5,8, Hiromi Yanagisawa1,5 (1. Life Science Center for Survival Dynamics, TARA, University of Tsukuba, Tsukuba, Japan, 2. School of Integrative and Global Major, University of Tsukuba, Tsukuba, Japan, 3. Department of Biomolecular Medicine, Ghent University, Ghent, Belgium, 4. Thoracic and Cardiovascular Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan, 5. Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, 6. Department of Cardiology and Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium, 7. Oregon Health and Science University, Oregon, USA, 8. Laboratory for AI Biology, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan)
Comment()

[1P-141]Analysis of the interaction between nuclear receptor ARP1 and a metallophosphoesterase domain-containing protein

○Shin-ichiro Honda1, Daichi Aso1, Manami Asari1, Chise Taniguchi1 (1. Fukuoka university)
Comment()

[1P-142]Stable Long-Term Preservation of Biological Samples via Sclerotia in Myxomycetes

○Tsuchida Kentaro1,2, Masui Mana2,3, Kono Nobuaki1,2,3 (1. Dept. Environ. Info. Stud., Keio Univ., 2. Inst. Adv. Biosci., Keio Univ., 3. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ.)
Comment()

[1P-143]Phosphorylation of Transcription factor NRF1 at a conserved locus controls its localization and transcriptional activity

○Gleb Shamrin1, Hsin-Yi Chen1 (1. Taipei Medical University, Ph.D. Program for Cancer Molecular Biology and Drug Discovery)
Comment()

[1P-144]Rapid CRISPR-Cas perturbation of cis-regulatory elements allows for decoding of complex transcriptional regulation

○Toyoaki Natsume1, Ryoko Wada1, Hideya Kawaji1 (1. Research Center for Genome & Medical Sciences, Tokyo Metropolitan Institute of Medical Science)
Comment()

[1P-145]fanta.bio: a database of transcriptional regulation by cis-regulatory elements

○Takeya Kasukawa1, Scott Walker1, Akira Hasegawa1, Nishad Thalhath1, Tomoe Nobusada1, Saumya Agrawal1, Toyoyuki Takada2, Hiroshi Masuya2, Hideya Kawaji3 (1. RIKEN IMS, 2. RIKEN BRC, 3. TMIMS)
Comment()

[1P-148]A novel transcription factor YheO for switching carbon source metabolism in Escherichia coli K-12

○Yuina Akeo1, Ikki Kobayashi1, Tomohiro Shimada1 (1. Meiji Univ.)
Comment()

[1P-150]Identification of heart failure-responsive transcription factors using proximity-labeling

○Taichi Sumida1, Hijiri Inoue1, Ken Matsuoka2, Seiji Takashima1,2 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Graduate School of Medicine)
Comment()

[1P-151]A Generalizable Footprint Analysis Framework for Gene-Region-Specific Transcription Factor Binding Prediction from ATAC-seq: Utilizing Pseudo-Read Modeling and Redefined Footprint Metrics.

○Hijiri Inoue1,3, Ken Matsuoka2,1, Seiji Takashima1,2 (1. Osaka Univ. Frontier Biosciences., 2. Osaka Univ. Medicine., 3. JSPS.)
Comment()

[1P-152]Establishment of reporter cells to quantify the transcription from RPS19 gene promoter

○Yoshiki Ishihara1, Yuri Ando1, Koji Kasahara1 (1. tokyo university of agriculture)
Comment()

[1P-153]The effect of osmotic stress on pre-mRNA cleavage factor Im 25kDa mRNA/protein expression

○Hidefumi Fukumitsu Fukumitsu1, Hitomi Soumiya1 (1. Gifu Pharmaceutical University)
Comment()

[1P-154]Characterization of the human EP300 and adenoviral early gene promoters and their responses to n-butyric acid

○Fumiaki Uchiumi1, Hideaki Furuya1, Shigeru Hanamata1, Nozomu Hanaoka2, Shuichi Hashimoto1 (1. Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Laboratory of Unidentified Pathogen Investigation, Center for Emergency Preparedness and Response, National Institute of Infectious Diseases, Japan Institute for Health Security)
Comment()

[1P-155]The phage-derived Cro/OR3 system enables targeted gene expression and cell manipulation in zebrafish

Kimiko Saka1, Yukiko Yoshida1, Saki Yamaura1, ○Kazuhide Asakawa Asakawa1,2 (1. National Institute of Genetics, 2. SOKENDAI)
Comment()

[1P-156]NAISTO: A Network Inference Method Integrating Graphical LASSO and Prior Biological Knowledge

○Toshiya Kokaji1, Noriaki Sasai1, Yuichi Sakumura1 (1. NARA Institute of Science and Technology)
Comment()

[1P-157]Dynamics of Nucleolar Formation and Ribosomal RNA Transcription in Zebrafish Early Embryos

○Chisato Negishi1, Mika Saotome2, Satoru Ide2, Hiroshi Kimura1,2 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
Comment()

[1P-158]Impacts of Cell Ranger versions on Chromium gene expression data

○Imad Abugessaisa1,2,3, Akira Hasegawa1, Scott James Walker1, Shintaro Katayama 4,5, Juha Kere4,5,6, Takeya Kasukawa1 (1. Laboratory for Large-Scale Biomedical Data Technology, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan. , 2. Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), The University of Osaka, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan, 3. Graduate School of Medicine and Faculty of Medicine, The University of Osaka, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan, 4. Folkhälsan Research Center, Biomedicum Helsinki, Haartmaninkatu 8, FI-00290 Helsinki, Finland, 5. Department of Biosciences and Nutrition, Karolinska Institutet, NEO, Blickagången 16, SE-141 83 Huddinge, Sweden, 6. Stem Cells and Metabolism Research Program, Biomedicum Helsinki, FI-00290 Helsinki, Finland)
Comment()

[1P-159]Pervasive transcription readthrough arrests cellular growth of epigenetically altered cancers

○Chihiro Nakayama1, Reo Shimatani1, Shoko Ito1, Takayuki Nojima1 (1. Kyushu University)
Comment()

[1P-160]Discovery of thermal sensitizers that inhibit heat-induced SAFB granule formation

○Kazunori Watanabe1, Yuji Furutani1, Natsuki Shimasaki1, Riko Yamada1, Takashi Ohtsuki1 (1. Okayama university)
Comment()

[1P-161(1PS-13-03)]Block Copolymer Micellization: A Novel Design Principle for RNA-Protein Complex Assembly

○Tomohiro Yamazaki1,2, Ichiro Taniguchi1, Tetsuya Yamamoto3, Sylvie Souquere4, Sota Umezaki1, Shinichi Nakagawa5, Gerard Pierron4, Tetsuro Hirose1,2,6 (1. FBS, The Univ. of Osaka, 2. Grad. Sch. Sci., The Univ. of Osaka, 3. ICReDD, Hokkaido Univ., 4. CNRS, 5. Pharm. Sci., Hokkaido Univ., 6. OTRI, The Univ. of Osaka)
Comment()

[1P-162]Functional analysis of mRNA cap 2'-O-methylation

○Atsushi Kasuga1, Chisa Shiraishi1, Kazuya Ichihara1, Naoko Abe2, Hiroshi Abe2, Akinobu Matsumoto1 (1. Division of Biological Science, Graduate School of Science, Nagoya University, 2. Division of Chemistry, Graduate School of Science, Nagoya University)
Comment()

[1P-163]The nascent chain-dependent localization mechanism of smallish mRNA

○Hiroto Yoshida1, Hideki Yoshida1 (1. Kyoto Institute of Technology)
Comment()

[1P-164]Functional role of circular RNAs in postnatal brain development and disorders

○Luc Gailhouste1, Aya Ito-Ishida1 (1. RIKEN Center for Brain Science)
Comment()

[1P-165]Comparison of efficient purification methods of circular mRNA

○Shiryu Kajihara1, Kosuke Fukuchi1, Naoko Abe1, Yuko Nakashima1, Fumitaka Hashiya2, Hiroshi Abe1,3 (1. Grad. Sch. of Sci., Nagoya Univ., 2. RCMS, Nagoya Univ., 3. iGCORE)
Comment()

[1P-167(1AS-14-04)]Thermo-sensing regulatory mechanisms underlying temperature-dependent splicing controlled by nuclear stress bodies

○Tsuyoshi Ueno1, Shungo Adachi2, Ichiro Taniguchi3, Nobuo Noda4,5, Kensuke Ninomiya3, Tetsuro Hirose1,3,6 (1. Department of Biological Sciences, Graduate School of Science, The university of Osaka, 2. National Cancer Center Research Institute, 3. Graduate School of Frontier Biosciences, The university of Osaka, 4. Institute for Genetic Medicine, Hokkaido University, 5. Institute of Microbial Chemistry, 6. Institute for Open and Transdisciplinary Research Initiatives)
Comment()

[1P-168]Engineering of Abyssicoccus albus Cas9 recognizing a unique PAM sequence for genome editing applications

○Akiyoshi NAKAMURA1, Reika HASEGAWA2, Hiroshi YAMAMOTO1, Tsubasa YANO2, Yoichi MAKINO3, Nobutaka MITSUDA1, Seiichiro ITO3, Teruhiko TERAKAWA2, Shigeo S SUGANO1 (1. AIST BPRC, 2. Inplanta Innovations Inc., 3. TOPPAN Holdings Inc.)
Comment()

[1P-169]Investigating the relationship of molecular profile between facial and scalp skin – Application of Skin Surface Lipid-RNA (SSL-RNA) analysis

○Hitomi Suzuki1, Shoudai Tanaka1, Yousuke Natori1, Takayoshi Inoue1 (1. Kao Corporation)
Comment()

[1P-170]Prediction of tRNA secondary structure using chemical probing and next generation sequencing

Komei Yanagihara1, Futa Konishi1, ○Ryota Yamagami1 (1. Ehime University, Graduate School of Science and Engineering,)
Comment()

[1P-171]Analysis of tRNA queuosine modification in zebrafish embryogenesis and adult tissues

○Ryota Matsue1, Toru Irie1, Kota Ishibashi2, Kimi Wakabayashi1, Yuichiro Mishima1 (1. Division of Life Sciences, Graduate School of Life Science, Kyoto sangyo university, 2. Department of Biosciences, School of Biological and Environmental Sciences, Kwansei Gakuin University)
Comment()

[1P-172]Regulatory mechanism of alternative splicing of KIT juxta-membrane region and isoform expression features

○Rikuto Goto1, Naoaki Sakamoto1, Akinori Awazu1 (1. Hiroshima University)
Comment()

[1P-173]The structure of genome RNA of SARS-CoV-2 has been revealed by single-molecule fluoresecence spectroscopy.

○Takahiro Kimura1,2, Shion Ishikawa1,2, Shinnosuke Saitou1,2, Yuuhei Yamano1, Kazumitsu Onizuka1,3, Fumi Nagatsugi1,3, Shilpi Laha4, Athi N Naganathan4, Yuji Itoh1,2,3, Satoshi Takahashi1,2,3 (1. IMRAM, Tohoku Univ., 2. Grad. Sch. Life Sci., Tohoku Univ. , 3. Grad. Sch. Sci., Tohoku. Univ. , 4. IITM)
Comment()

[1P-174]Loss of starvation and light sporulation trigger in Myxomycetes Physarum roseum

○Mana Masui1,2, Phillip Yamamoto2, Nobuaki Kono1,2,3 (1. Syst. Biol. Program, Grad. Sch. Media Gov., Keio Univ., 2. Inst. Adv. Biosci., Keio Univ., 3. Dept. Environ. Info. Stud., Keio Univ.)
Comment()

[1P-175]The effect of a novel non-coding RNA L-IST on translation of Se-containing proteins using its functional sequences

○Yukihiro Inenaga1, Yuichiro Mita2, Kohei Kishi1, Noriko Noguchi1 (1. Doshisha University, 2. Doshisha Univ.)
Comment()

[1P-176(1PS-13-05)]Functional Analysis of Core tRNA Modifications Using an E. coli 11KO Model

○Karolina Honzejkova1, Gen-Ichiro Uechi1, Paola Laurino1,2 (1. Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Japan, 2. Institute for Protein Research, Osaka University, Suita, Japan)
Comment()

[1P-177]Mitotic chromosome associated mRNAs is involved in chromosome dynamics

○Ayumi Morishita1, Yukino Minami1, Takashi Ideue2 (1. Graduate School of Science, Kumamoto Univ., 2. Faculty of Advanced Science and Technology, Kumamoto Univ.)
Comment()

[1P-178]Temperature-dependent splicing regulation of mRNA encoding heat-related coactivator PGC1α

○Manaka Fujieda1, Ayana Ueno1, Chisaki Nakamura1, Momoka Sawada1, Koya Kawaguchi1, Natsuki Aoto1, Kyoka Imoto1, Robert G. Roeder2, Natsumi Hasegawa1, Mitsuhiro Ito1,2 (1. Medical Biophysics, Kobe Univ., Kobe, Japan, 2. Biochem. & Mol. Biol., the Rockefeller Univ., New York, U.S.A.)
Comment()

[1P-179]Comprehensive molecular analysis of colorectal cancer progression through microRNA extraction and profiling from formalin-fixed paraffin-embedded colorectal cancer tissues

○Kenichi Nonaka1, Arizumi Naruse2, Arizumi Kikuchi2, Kentaro Suzuki1, Yoshifumi Yuto3 (1. Daiyukai General Hospital, 2. Daiyukai Research Institute for Medical Science, 3. Kanto Chemical Co., Inc.)
Comment()

[1P-180]Detection of mRNA-based medicines from plasma by direct SATORI for gene doping control

○Risako Furukawa1, Hajime Shinoda2, Teruaki Tozaki1, Asami Makino2, Mami Yoshimura2, Tatsuya Iida2, Koki Kawate1, Kikuchi Mio1, Taichiro Ishige1, Yuji Takahashi3, Tomohiro Kato3, Hironaga Kakoi1, Emiko Fukui4, Rikiya Watanabe2 (1. Laboratory of Racing Chemistry, 2. PRI, RIKEN, 3. JRA, 4. Utsunomiya Univ.)
Comment()

[1P-181(1AS-04-05)]Biogenesis mechanism and significance of intronic polycistronic H/ACA snoRNAs in Drosophila melanogaster

○Mitsunaga Hamashima1, Tomohiro Yamano1, Shigeki Hirakata1, Takashi Fukaya2, Mikiko C. Siomi1 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)
Comment()

[1P-182]Comprehensive Characterization of Oil-Induced RNA Adducts by RNA Adductomics

○Yu-An Chang1, Po-Cheng Shao1, Ting-Yu Lin2, Yan-Jhen Lin1, Jia-Yuan Chen2, Yuan-Jhe Chang1, Mu-Rong Chao1, Chiung-Wen Hu2 (1. Department of Occupational Safety and Health, Chung Shan Medical University, 2. Department of Public Health, Chung Shan Medical University)
Comment()

[1P-183]Circular RNA synthesis from circular DNA template

○Yui Yoneda1, Masayuki Suetsugu1 (1. Rikkyo Univ.)
Comment()

[1P-184]RNAMergeDistill: Multi-Teacher Knowledge Distillation for RNA Language Model

○Kazuma Hashimoto1, Keisuke Yamada2, Michiaki Hamada3,4,5 (1. Graduate School of Advanced Science and Engineering, Waseda University, 2. University of Pennsylvania, 3. Faculty of Science and Engineering, Waseda University, 4. Cellular and Molecular Biotechnology Research Institute (CMB), National Institute of Advanced Industrial Science and Technology (AIST), 5. Graduate School of Medicine, Nippon Medical School)
Comment()

[1P-185]Identification of Key Factors for Stability Optimization in mRNA Therapeutics

○Yuyuko Abe1, Keisuke Yamada1,3, Michiaki Hamada1,2 (1. Waseda University, 2. National Institute of Advanced Industrial Science and Technology, 3. University of Pennsylvania)
Comment()

[1P-186]Characterization of RNA-binding Properties of HNRNPC’s Two Distinct Regions

○Ichiro Taniguchi1, Tetsuro Hirose1 (1. UOsaka)
Comment()

[1P-187]Functional Analysis of the Hfq Protein in Escherichia coli tatC Mutant

○Kaho Ozaki1, Chizuru Onoda1, Naoki Sudo2, Yasuhiko Sekine1 (1. Rikkyo Univ., 2. Kyorin Univ.)
Comment()

[1P-188(1AS-01-06)]Exploring the dark proteome through translation initiation profiling

○Kazuya Ichihara1, Taichi Shiraishi1, Haruhiko Morita2, Chisa Shiraishi1, Atsushi Hatano3, Serina Tokita3,4, Takayuki Kanaseki3,4, Shungo Adachi5, Yutaka Suzuki6, Masaki Matsumoto3, Teppei Shimamura2,7, Akinobu Matsumoto1 (1. Division of Biological Science, Graduate School of Science, Nagoya University, 2. Department of Computational and Systems Biology, Division of Biological Data Science, Medical Research Laboratory, Institute for Integrated Research, Institute of Science Tokyo, 3. Graduate School of Medical and Dental Sciences, Niigata University, 4. Department of Pathology, Sapporo Medical University, 5. Department of Proteomics, National Cancer Center Research Institute, 6. Univ. Tokyo, 7. Nagoya Univ.)
Comment()

[1P-190]The roles of polyP in the translational regulation of the anillin mRNA

○Naoya Takahashi1, Chihiro Tanaka1, Tomoki Hirashima1, Hideki Yoshida1 (1. Kyoto Institute of Technology)
Comment()

[1P-192]Impact of translational frameshift motifs on Saccharomyces cerevisiae proteins

○Margaux Aubel1, Paola Laurino1 (1. Okinawa Institute of Science and Technology)
Comment()

[1P-193]Functional analysis of a novel arrest peptide identified from Brevibacillus genus

○Yudai Ogasawara1, Keigo Fujiwara2, Hiraku Takada3, Shinobu Chiba1 (1. Faculty of life sciences, Kyoto Sangyo University, 2. National Institute of Genetics, 3. Toyoma Prefectural University)
Comment()

[1P-194]The expression of YIPF Golgi membrane proteins is controlled by multilayered regulatory mechanisms

○Nobuhiro Nakamura1, Tokio Takaji1,2, Yurika Nakanishi1 (1. Kyoto Sangyo University , 2. CIRA, Kyoto University)
Comment()

[1P-195]Analysis of translation dynamics of the proliferate state and the quiescent state of neural stem cells

○Mayu Hayashi1, Taichi Shiraishi1, Kazuya Ichihara1, Koshi Imami2, Taeko Kobayashi3, Akinobu Matsumoto1 (1. Nagoya Univ., 2. RIKEN , 3. Tokyo Univ.)
Comment()

[1P-196]Elucidation of the function of hypusinated eIF5A in the Drosophila intestine.

○Yuna Matsumura1, Hideki Yoshida1 (1. KYOTO INSTITUTE OF TECHNOLOGY)
Comment()

[1P-197]Impact of Redox Regulation on Protein Expression in a Reconstituted Cell-Free System

Tomoe Fuse-Murakami1, Shohei Terazawa2, Riddhi Gondhalekar2, Shohei Ito2, Seiichi Miyawaki3, Yusuke Mizukami3, Willan P Salgado3, Zening Yang4, Kosuke Fujishima5, ○Takashi Kanamori1 (1. GeneFrontier Corporation, 2. LST, Science Tokyo, 3. MCT, Science Tokyo, 4. EPS, Science Tokyo, 5. ELSI, Science Tokyo)
Comment()

[1P-198]Elucidation of the evolution of the translation system based on the sequence reconstruction of ancestral aminoacyl-tRNA synthetase

○Kakeru Sunaga1, Ryutaro Furukawa1,2, Akihiko Yamagishi1, Shin-ichi Yokobori1 (1. Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2. Faculty of Human Sci., Waseda Univ.)
Comment()

[1P-199]Functional and Structural Approaches to Understanding Stop Codon Readthrough

○Koki Nomura1, Yusuke Ohkubo1, Arisa Suto2, Takashi Matsui2, Yoshio Kodera2, Takeshi Yokoyama1, Yoshikazu Tanaka1 (1. Tohoku Univ., 2. Kitasato Univ.)
Comment()

[1P-200]Functional analysis of a novel arrest factor YwcI from Bacillus subtilis

○Momoka Sano1, Keigo Fujiwara2, Shinobu Chiba1 (1. Kyoto Sangyo University Graduate School, 2. National Institute of Genetics)
Comment()

[1P-201]Pdcd4-mediated translational control in immune cells and its role in inflammatory responses

○Yuta Takahashi1, Kazuya Ichihara1, Akinobu Matsumoto1 (1. Nagoya University)
Comment()

[1P-202]Structural insights into RaiA-type hibernating ribosome competing with RNase I

○Takehito Tanzawa1, Atsushi Minami2,3, Tetsuhiro Ogawa2,4, Hideji Yoshida5, Takayuki Kato1,6 (1. IPR, UOsaka, 2. Grad. Schl. of Agri. & Life Sci., UTokyo, 3. Fac. of Sci. & Eng., Waseda Univ., 4. CRIIM, UTokyo, 5. Fac. of Med., Osaka Med. & Pharm. Univ., 6. CAMaD, UOsaka)
Comment()

[1P-203]Mechanism of Ribosome Stalling at C2H2–Zinc Finger Arrays

○Masashi Kondo1, Kota Ishibashi2, Yuichiro Mishima1 (1. Division of Life Sciences, Graduate School of Life Science, Kyoto Sangyo University, 2. Department of Biosciences, School of Biological and Environmental Sciences, Kwansei Gakuin University)
Comment()

[1P-204]Molecular basis of acyl acceptor selection mechanisms in glycerolipid acyltransferases harnessing the structure models with AlphaFold3

○Keiichiro Murayama1, Atsushi Hijikata2 (1. Grad. Sch. Life Sci., Tokyo Univ. Pharm. Life Sci., 2. Sch. Life Sci., Tokyo Univ. Pharm. Life Sci.)
Comment()

[1P-205]Structural analysis of the green fluorescent cAMP indicator gCarvi

○YURI TOMABECHI1,2, Kyoko Hanawa-Suetsugu2, Kazuharu Hanada2, Hiroya Tsuda3, Naoto Saitoh3, Mikako Shirouzu1,2 (1. YCU, 2. RIKEN-IMS, 3. DU)
Comment()

[1P-206]Developing Antibody-Antigen Interaction Prediction Models for Drug Discovery Applications

○Takashi Fujiwara1,2, Hideyuki Shimizu1,2 (1. Department of AI Systems Medicine, M&D Data Science Center, Institute of Integrated Research, Institute of Science Tokyo, 2. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-207]Predicting interactions between disease-related proteins and intracellular proteins by using AlphaFold

○Shinichi Kawaguchi1, Toshie Kai1 (1. The university of Osaka)
Comment()

[1P-208]Dynamic movement of recombinant FGFR1-FRS2α complex observed at single-molecule level by High Speed-Atomic Force Microscopy (HS-AFM)

○Yuma Myokan1, Saren qiqige1, Tsunaki Hongu1, Katsuya Sakai2,3, Yilmaz Neval2,3, Kunio Matsumoto2,3, Mikihiro Shibata3,4, Noriko Gotoh1 (1. Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, 2. Division of Tumor Dynamics and Regulations, Cancer Research Institute, Kanazawa University, 3. WPI-Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, 4. High-speed AFM for Biological Application Unit, Institute for Frontier Science Initiative, Kanazawa University)
Comment()

[1P-209]Structural and functional analysis of interaction between the replication fork barrier and Fob1 in budding yeast

○Manato Tsuji1, Aoi Makita2, Takeshi Yokoyama3, Takehiko kobayashi4, Masahiko Harata1,2, Chihiro Horigome1,2 (1. Tohoku Univ. , 2. Tohoku Univ., 3. Tohoku Univ. , 4. Tokyo Univ.)
Comment()

[1P-210]Time-resolved X-ray Crystallography of a Double Mutant of the Human DNA Oxidative Damage Repair Enzyme, hOGG1

○Mami Shimizu1, Masayuki Morikawa2, Yoshiyuki Tanaka2, Masaki Unno1,3 (1. Ibaraki Univ., 2. Tokushima Bunri Univ., 3. RECAS)
Comment()

[1P-211]Structural analysis of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by cryo-electron microscopy

○Mutsuko Niino1, Kazushige Katsura1, Kota Yoshimura2, Yoshiko Ishizuka-Katsura1, Yuki Miyamoto3, Mayumi Yonemochi1, Kazuharu Hanada1, Junji Yamauchi4, Richard W Wong2, Mikako Shirouzu1 (1. RIKEN IMS, 2. Kanazawa Univ., 3. National Research Institute for Child Health and Development, 4. Tokyo University of Pharmacy and Life Sciences)
Comment()

[1P-212]Cryo-EM structure analysis of Fe-S cluster biosynthesis scaffold protein SufBC2D

○Misato Tsuji1, Josei Uchida2, Yumiko Motoyama2, Takeshi Yokoyama1, Kei Wada2, Yoshikazu Tanaka1 (1. Tohoku University, 2. Miyazaki University)
Comment()

[1P-213]CryoEM structures of DOCK1-ELMO1 complex with upstream regulators on lipid membranes

○Yurika Yamada1, Yoshiko Katsura-Ishizuka1, Kazuharu Hanada1, Takehiro Shinoda1, Sayoko Kohno1, Mayumi Yonemochi1, Mutsuko Kukimoto-Niino1, Mikako Shirouzu1 (1. RIKEN, IMS)
Comment()

[1P-214]Structural basis for BTG2–Caf1-dependent deadenylation regulated by dynamic interactions between poly(A) and PABPC1

○Nao Kataoka1, Mariko Yokogawa1, Yuichiro Ishii1, Erika Shiro1, Hiroka Takashima1, Ryoichi Sawazaki1, Takeru Sagae1, Koichi Ogami2, Shin-ichi Hoshino2, Masanori Osawa1 (1. Grad. Sch. of Pharm Sci., Keio Univ., 2. Grad. Sch. of Pharm Sci., Nagoya City Univ)
Comment()

[1P-215]Effect of charge state on ion mobility separation of peptide isomers

○Kazuto Mochizuki1, Eriko Kishino1 (1. Tokyo Metropolitan Industrial Technology Research Institute)
Comment()

[1P-216]Elucidation of the Kinase Binding Specificity of Staurosporine through the Integration of Quantum Chemical Calculations and X-ray Crystallographic Analysis

○Ruri Mihata1, Riko Higashino2, Mayu Kitano3, Shuhei Miyakawa1, Yu-Shi Tian1, Daisuke Takaya1, Takayoshi Kinoshita3, Shigenori Tanaka4, Kaoru Fukuzawa1 (1. Grad. Sch. Pharm. Sci., The Univ. of Osaka. , 2. Grad. Sch. Sys. Info., Kobe Univ., 3. Grad. Sch. Sci., Osaka Metropolitan Univ., 4. Mol. Photo. Res. C., Kobe Univ.)
Comment()

[1P-217]Tumor suppressor p53 stabilization by DARPin on the nucleosomal DNA

○Yuchen Jin1,2, Kenta Echigoya1, Yüksel Büşra 3,4, Mitsuo Ogasawara1, Yoshimasa Takizawa1, Volker Dötsch3, Hitoshi Kurumizaka1,2 (1. Institute for Quantitative Biosciences, The University of Tokyo, 2. Department of Biological Sciences Graduate School of Science The University of Tokyo, 3. Institute of BiophysicalChemistry Goethe University,Frankfurt, 4. IMPRS on Cellular Biophysics,Frankfurt)
Comment()

[1P-218]Inducing Protein Dynamic Structures by Manipulating the Latent Space of Deep Generative Models

○Shosuke Suzuki1, Toshiyuki Amagasa2 (1. Univ. of Tsukuba, 2. CCS, Univ. of Tsukuba)
Comment()

[1P-219]In Situ Cryo-EM Structure of V-ATPase

○Fuka Ueda1, Yui Nishida1, Atsuko Nakanishi2, Kaoru Mitsuoka3, Ken Yokoyama1 (1. Grad.Sch. Life Sci., Kyoto Sangyo Univ., 2. IPR, Osaka Univ., 3. Research Center for Ultra-High Voltage Electron Microscopy, Osaka Univ.)
Comment()

[1P-220]Cryo-EM Structure Analysis of Bombesin Receptors for Itch and Cancer: A Platform for Designing Subtype-Selective Inhibitors

○Akitoshi Inoue1, Asato Kojima2, Chiyo Suno1, Tomoyo Takai1, Mika Hirose3, Yukihiko Sugita4, Takayuki Kato3, Hideaki Kato2, Takuya Kobayashi1, Ryoji Suno1 (1. Kansai Medical Univ., 2. Univ. Tokyo, 3. Univ. Osaka, 4. Kyoto Univ.)
Comment()

[1P-221]Analysis of the interaction between a dormancy regulator and DNA Gyrase from Mycobacterium tuberculosis and sample preparation for Cryo-EM

○Yuri Nakagawa1, Yuuka Kawanobe1, Koki Watanabe1, Akihito Nishiyama2, Yuriko Ozeki2, Sohkichi Matsumoto2, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ, 2. Grad. Sch. of Med. and Dent. Sci., Niigata Univ)
Comment()

[1P-222]Development and characterization of CA9-targeting VHH antibodies created through CDR redesign

○Yuma Ishiwata1, Koki Kamijo1, Kotaro Miyamoto1, Tetsuya Kadonosono1 (1. Institute of Science Tokyo)
Comment()

[1P-223]Crystal structure of Pth2 from Candidatus Lokiarchaeum sp. GC14_75

○Aoi Kawashima1, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ.)
Comment()

[1P-224]Exploration of interaction sites on RNA polymerase with a dormancy regulator in Mycobacterium tuberculosis and their interaction analysis

○Atsushi Kato1, Kodai Kamba1, Ken-ichiro Yamamoto2, Akihito Nishiyama3, Yuriko Ozeki3, Sohkichi Matsumoto3, Kosuke Ito1,2 (1. Grad. Sch. of Sci. and Tech., Niigata Univ, 2. Dept. of Biol., Fac. of Sci., Niigata Univ, 3. Grad. Sch. of Med. and Dent. Sci., Niigata Univ)
Comment()

[1P-225]Recognition mechanism of the G-quadruplex in the telomerase (TERT) promoter by the telomere-binding protein TRF2

○Junichi Kurita Kurita1, Yuuka Hirao1, Yoshifumi Nishimura1 (1. Yokohama City University)
Comment()

[1P-226]Multidimensional optical measurement and quality control of structural polymorphism of synuclein aggregates

○Masafumi Ohtsubo1, Yu Nagashima1 (1. Hamamatsu University School of Medicine)
Comment()

[1P-227]CryoET analysis of the symbiotic mechanism between Nanobdellati archaeon MJ1 and its host archaeon MJ1HA

○Sakurako Goto1, Shingo Kato2, Mari Takahashi1, Ayako Sakamoto1, Atsushi Yamagata1, Yongchan Lee3, Haruhiko Ehara1, Mayuko Sato4, Kiminori Toyooka4, Moriya Ohkuma2, Takuhiro Ito1 (1. RIKEN IMS, 2. RIKEN JCM, 3. Yokohama City University, 4. RIKEN CSRS)
Comment()

[1P-228]Unveiling the Molecular Structure of Protein Complexes during Influenza A Virus Cell Entry

○Takuto Washizawa1, Atzin Bolanos-Ceron2, Koichi Inagaki1, Takayuki Uchihashi3, Hiroshi Kimura1,2, Yohei Yamauchi2,4, Yasuyuki Miyake1,2,5 (1. Department of Virology, Nagoya University School of Medicine, 2. Department of Virology, Nagoya University Graduate School of Medicine, 3. Laboratory of Biomolecular Dynamics and Function, Nagoya University Graduate School of Science, 4. Molecular Medicine Laboratory, IPW, D-CHAB, ETH Zurich, 5. Nagoya University Institute for Advanced Research)
Comment()

[1P-229]Molecular Dynamics (MD) Simulations to Explore the Common Mechanisms of Pathological Amyloid Disaggregation by Small Molecules

○Hideyuki Miyatake1, Qimin Jia1,2, Takashi Isoshima3, Atsushi Takata1, Motomasa Tanaka1,2 (1. RIKEN Center for Brain Science, 2. Graduated School of Saitama Univ., 3. RIKEN Center for Advanced Photonics)
Comment()

[1P-230]Drug design for cyclin-dependent kinase 9 (CDK9) inhibitors in silico

○Kaori Asamitsu1, Takatsugu Hirokawa2, Takashi Okamoto1 (1. Nagoya City University, 2. University of Tsukuba)
Comment()

[1P-231]Why does ornithine not constitute protein: A Quantum Chemical Calculation Analysis

○Ayato Mizuno1, Tomoki Nakayoshi1,2, Koichi Kato1,3, Akifumi Oda1 (1. Grad. Sch. Pharm. Meijo Univ., 2. Inst. Adv. Res., Nagoya Univ., 3. Fac. Pharm. Sci., Shonan Univ. Med. Sci.)
Comment()

[1P-232]Dynamics analysis and Biochemical identification of TOM complex trimer form

○Nanako Kobayashi1, Kana Kuzasa1, Satoshi Omura2, Kenichiro Imai3, Osamu Nureki2, Noriyuki Kodera4, Toshiya Endo5,6, Yuhei Araiso1 (1. Dept. of Clin. Lab. Sci., Div. of Health Sci., Kanazawa Univ., 2. Dept. of Bio Sci., Tokyo Univ., 3. Cellular and Molecular Biotechnology Research Institute, AIST., 4. WPI-NanoLSI, Kanazawa Univ., 5. Fac. of Life Sci., Kyoto Sangyo Univ., 6. Inst. of Protein Dynamics, Kyoto Sangyo Univ.)
Comment()

[1P-233]Development of the "AlissAID" system degrades target protein using single domain antibodies.

○Yoshitaka Ogawa1, Kohei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Nagoya univ.)
Comment()

[1P-234]Breaking the Limits of Single-Cell Proteomics via Materials and Separation Science

○Eisuke Kanao1, Akamatsu Koshin1, Shunsuke Tanaka1, Ayana Tomioka1, Akane Omori1, Ishihama Yasushi1 (1. Kyoto Univ.)
Comment()

[1P-235]Profiling of i-motif DNA binding proteins via fingerprint-targeting enrichment

Yuki Ban1, Yuka Ando1, Shinichi Sato2, ○Junpei Yamamoto1 (1. Graduate School of Engineering Science, The University of Osaka, 2. The Frontier Research Institute for Interdisciplinary Sciences, Tohoku University)
Comment()

[1P-236]Analysis of the mechanism of high molecular weight species formation of tetrahydrofolate metabolizing enzyme.

Rira Akutagawa1, Sara Yanagisawa1, Yutaka Tanaka1, Fumie Itoh1, Sachiko Komatsu1, Kazuhiro Watanabe1, Tsutomu Fujimura1, ○Masato Sasaki1 (1. Tohoku Medical and Pharmaceutical University)
Comment()

[1P-237]Mechanism of Indoleamine 2,3-dioxygenase-1 inhibition by Propanamide derivative

Daisuke Tsuji1, Koharu Waki1, Kazuki Yamanoi1, Shota Takeda2, Osamu Ohno2, Takao Saito3, Kenji Matsuno1, ○Reiko Akagi1 (1. Dept. of Pharmacy, Yasuda Women’s Univ., 2. Sch. of Adv. Eng., Kogakuin Univ., 3. Dept. of Chemistry, Tokyo Univ. of Science)
Comment()

[1P-238]Hair shaft proteomics of AGA patients and non-alopecia subjects revealed significant decrease of WNT signal related molecules in AGA ones.

○Keigo Sugimoto1, Takatoshi Nakagawa2, Shigeki Inui2 (1. Aderans Company Limited, 2. Graduate School of Medicine, Osaka University)
Comment()

[1P-239]Research on the self-aggregation mechanism of ubiquitinated CPEB3

○Harunobu Saito1, Yujin Lee1, Keiju Osumi1, Motoharu Ueno2, Daichi Morimoto3, Naotaka Sekiyama2, Masatomo So1, Ayako Furukawa1, Kenji Sugase1 (1. Kyoto Univ. Graduate school of agriculture, 2. Kyoto Univ. Graduate school of science, 3. Kyoto Univ. Graduate school of engineering)
Comment()

[1P-240]Cell-free synthesis of active flavoproteins coupled with FMN and FAD synthesis from riboflavin

○Yukiko Kenyoshi1, Michiyo Hishikawa1, Akari Ikeda2, Takayoshi Matsuda1 (1. SAIL Technologies Inc., 2. Taiyo Nippon Sanso Corporation)
Comment()

[1P-241]Refinement of E.coli-based cell-free protein synthesis system for practical use

○Takayoshi Matsuda1, Michiyo Hishikawa1, Yukiko Kenyoshi1 (1. SAIL Technologies Inc.)
Comment()

[1P-242]Cell-free synthesis of catalytically active kynurenine-3-monooxygenase

○Michiyo Hishikawa1, Akari Ikeda2, Takayoshi Matsuda1 (1. SAIL Technologies Inc., 2. Taiyo Nippon Sanso Corporation)
Comment()

[1P-244]Intrinsically Disordered Regions (IDR) and Liquid-Liquid Phase Separation (LLPS) in Rice Florigen Proteins

○Kengo Nakayama1, Mayu Enomoto1, Sayaka Yanagi1, Kyoko Furuita2, Takashi Kodama2, Miyanoiri Yohei2, Kenichiro Taoka3, Hiroyuki Tsuji4,5, Chojiro Kojima1 (1. Yokohama National University, 2. Institute for Protein Research, The University of Osaka, 3. Engineering Biology Research Center, Kobe University, 4. Kihara Institute for Biological Research, Yokohama City University, 5. Institute of Transformative Bio-Molecules, Nagoya University)
Comment()

[1P-245]A Pharyngeal Lysosomal Copper Transporter Regulates Cold-Induced Death in C. elegans

○Serina Yamashiro1, Satomi Mizuno1, Haruka Motomura1, Christopher J. Chang2, Akane Ohta1, Atsushi Kuhara1,3 (1. Laboratory of Molecular and Cellular Regulation Graduate school of Natural Science Konan University, 2. UC Berkeley, 3. PRIME, AMED)
Comment()

[1P-246]Chaperone activity of a highly charged intrinsically disordered protein is driven by non-specific electrostatics

○Arriel Fadhilah1, Yutaro Okumura1, Shin-ichiro Kido1,2 (1. Graduate School of Science, Nagoya City University, 2. Research Center for Biological Diversity, Nagoya City University)
Comment()

[1P-247]Identification of the interaction site between human neuroglobin and flotillin-1 using “module”-substituted chimeric globins.

○Nozomu Yoshida1, Nozomu Takahashi1, Kurara Takagane2, Takumi Yokosawa1, Keisuke Wakasugi1,2 (1. Graduate School of Arts and Sciences, The University of Tokyo, 2. Graduate School of Sciences, The University of Tokyo)
Comment()

[1P-248]Imaging Activation-Dependent CaMKII Cluster Dynamics and Analyzing Intermolecular Interactions by High-Speed AFM

○Taisei Suzuki1, Takashi Sumikama2,3, Hideji Murakoshi4, Mikihiro Shibata2,5 (1. Grad. Sch. NanoLS., Kanazawa Univ., 2. WPI-Nano Life Science Institute, Kanazawa Univ., 3. Grad. Sch. Biostudies, Kyoto Univ., 4. Supportive Center for Brain Research, NIPS, 5. InFiniti, Kanazawa Univ.)
Comment()

[1P-249]In vitro selection of human VH-domain antibody by PUREfrexRD .

○Kanehisa Kojoh1, Nobuhide Doi2, Takashi Kanamori1 (1. GeneFrontier Corporation, 2. Keio Univ)
Comment()

[1P-250]Exploring the molecular function of K48/K63-branched ubiquitin chains in protein degradation

○Shota Tomomatsu1, Nobuhide Ichigozaki1, Fumiaki Ohtake1 (1. Hoshi University)
Comment()

[1P-251]Improvement of fluorescent immunosensor for visualization of plant hormone in living cells

○ZIXU Feng FENG1, Hiroshi Aihara1, Shun Sakuraba2,3, Yanyan Hou4, Keisuke Yoshida5, Takanobu Yasuda5, Bo Zhu5, Toshiro Ito6, Tetsuya Kitaguchi4,5 (1. LST, Science Tokyo, 2. iQLS, QST, 3. Grad. Sch. Sci. Eng., Chiba U, 4. Cell Signaling Group, WABIOS, 5. CLS, IIR, Science Tokyo, 6. Grad. Sch. Sci. Eng., NAIST)
Comment()

[1P-252]DJ-1 counteracts cPGA, a novel acylating metabolite implicated in Parkinson’s disease.

○Shizuka Ogiwara1, Hidetaka Kosako2, Aiko Watanabe1, Noriyuki Matsuda1 (1. Medical Research Institute, Institute of Science Tokyo., 2. Institute of Advanced Medical Sciences, Tokushima University.)
Comment()

[1P-253]Molecular mechanism of cold tolerance acquisition by ice crystal binding proteins using C. elegans

○Saki NAKAUMURA NAKAUMURA1, Ryohei Kuriyama1, Daiki Shimose1, Yoichi Shinkai2, Yuka Ikemoto3, Masahiro Kuramochi1 (1. Graduate School of Science and Engineering, 2. Biomedical Research Institute, AIST, 3. JASRI)
Comment()

[1P-254]Identification of endogenous ligands for OR7C1 involved in the function of cancer stem cells

○Masaki Okajima1, Kaoru Hashimoto2, Suzuna Kozu2, Yoshihiko Hirohashi3, Yosuke Fukutani1,2 (1. Grad Sch of Advanced Interdisciplinary Science, Tokyo Univ., Agric and Technol., 2. Dept of Biotechnol and Life Sci., Tokyo Univ., Agric and Technol., 3. Dept of Pathol. Sapporo Med. Univ.)
Comment()

[1P-255]Elucidation of the hypoxic response mechanism of human fibroblast TIG3 through multi-functional proteomics

○Atsushi Hatano1, Tomoyo Takami1, Masaki Matsumoto1 (1. Graduate School of Medical and Dental Sciences, Niigata University)
Comment()

[1P-256]A study on protein function modification through insertion-deletion mutations

○Ryota Fujii1 (1. Mitsui Chemicals, Inc.)
Comment()

[1P-257]Functional Analysis of the Cold-Responsive Intrinsically Disordered Mini RNA Chaperone CISP in Barley

○Yutaro Okumura1, ARRIEL FADHILAH1, Shin-ichiro Kidou1,2 (1. Graduate School of Natural Sciences, Nagoya City University, 2. Research Center for Biological Diversity)
Comment()

[1P-258]Analysis of enolase condensates formed in vitro

○Koharu Alicia Senda1, Shiho Minakata2, Yoshiaki Sakurai2, Natsuko Miura1, Michihiko Kataoka1 (1. Dept. Appl. Biol. Chem., Grad. Sch. Agric., Osaka Metropolitan Univ. , 2. Equip. Shar. Ctr. Adv. Res. Innov., Osaka Metropolitan Univ.)
Comment()

[1P-259]Purification of mouse Abitram protein and its structural and functional analysis on actin filaments

○Yuki Hoshikawa1, Misaki Domoto1, Kentaro Noi3, Motoshi Kaya2, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Tokyo University, 3. Kobe University)
Comment()

[1P-260]Isolation and characterization of rabbit monoclonal antibodies suitable for proximity-dependent protein biotinylation analysis

○Mana Hamada1, Soh Tokunaga1, Kohdai Yamada1, Hiroyuki Takeda2, Tatsuhiko Ozawa3, Akira Nozawa1, Tatsuya Sawasaki1 (1. Division of Cell-Free Sciences, Pros, Ehime University, 2. Division of Proteo-Drug-Discovery Sciences, Pros, Ehime University, 3. Department of Life Sciences and Bioengineering, Faculty of Engineering, University of Toyama)
Comment()

[1P-261]The physiological significance of ER glutathione transport via TMX4

○Nanami Nunomura1, Chika Tsutsumi1,2, Ryo Ushioda1,2 (1. Kyoto Sango Univ., 2. Institute for Protein Dynamics)
Comment()

[1P-262]Co2+ potentiates immunogenicity of poorly immunogenic Japanese encephalitis virus envelope protein domain 3 by generating JEV-neutralizing antibodies in mice

○Md. Din Islam1, Takeshi Kurosu 2, Mami Okawa 1, Nanaka Morikoshi1, M. Monirul Islam3,4, Hiromichi Tsurui1,5, Yutaka Kuroda1,3 (1. Department of Biotechnology and Life Science, Faculty of Engineering, Tokyo University of Agriculture and Technology, 2. Department of Virology 1, National Institute of Infectious Diseases, 3. Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 4. Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Chittagong, 5. Department of Immunological Diagnosis, Juntendo University School of Medicine)
Comment()

[1P-263]Functional role of the trace-amine receptor TAAR5 on ammonia perception.

○Hiroto Koguma1, Mei Saito2, Kyosuke Shinohara1,2, Yosuke Fukutani1,2 (1. Dept of Advanced Interdisciplinary Science., Tokyo Univ. of Agric and Technol.,, 2. Dept of Biotechnol., Tokyo Univ. of Agric and Technol.,)
Comment()

[1P-264]Functional analysis of receptor transporting protein as an RNA-binding protein

○Chikako Tonoki1, Ryosuke Inoue2, Kyosuke Shinohara1,2, Yosuke Fukutani1,2 (1. Dept of Advanced Interdisciplinary Science., Tokyo Univ. of Agric and Technol., 2. Dept of Biotechnol., Tokyo Univ. of Agric and Technol.,)
Comment()

[1P-265]Phosphorylation of Lamina-associated polypeptide 2, one of the inner nuclear membrane proteins, promotes West Nile virus replication

○Haruto Eguchi1, Keisuke Maezono1,2, Thammahakin Passawat1, Thuy Thi Ngoc Duong1, Kentaro Yoshii3, Hiroaki Kariwa1,2, Shintaro Kobayashi1,2,4,5 (1. Hokkaido Univ., Vet., 2. Hokkaido Univ., IIZC, 3. Nagasaki Univ., CCPID, 4. Hokkaido Univ., IVReD, 5. Hokkaido Univ., OHRC)
Comment()

[1P-266]Protein complex turnover profiling using pSILAC-SEC-MS

○Tokichiro Abe1, Atsushi Hatano1, Masaki Matsumoto1 (1. Niigata university Graduate School)
Comment()

[1P-267]Elucidation of the Cause of Insolubility of Recombinant Norovirus GI.6 VP1 in the Silkworm-Baculovirus Expression System

○Yuto Tsurumi1, Akitsu Masuda2, Tomohito Tanihara3, Naoya Matunaga3, Shigehiro Ohdo3, Yuya Yoshida3, Yuma Terada3, Kengo Hamamura3, Kouta Mayanagi3, Lee Jaeman2, Hiroaki Mon2, Takahiro Kusakabe2 (1. Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 2. Faculty of Agriculture, Kyushu University, 3. Faculty of Pharmaceutical Sciences, Kyushu University)
Comment()

[1P-268]Development of Asbestos-binding Proteins Based on the Antifreeze Protein TmAFP

○Shogo Yamazaki1, Takenori Ishida1, Takeshi Ikeda1, Hisakage Funabashi1, Ryuichi Hirota1, Akio Kuroda1 (1. Hiroshima Univ.)
Comment()

[1P-269]Positive and negative regulation of cohesin by PDS5A/B

○Sumika Nakashotani1, Ryo Ishida1, Takuya Abe2, Ryotaro Kawasumi1, Koji Hirota1 (1. Tokyo Metropolitan University, 2. Tohoku Medical and Pharmaceutical University)
Comment()

[1P-270]The E2-Nanobody system: Targeted protein degradation by E2 ubiquitin-conjugating enzyme and exploration of its molecular mechanism

○Junpei Kida1, Kohei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Graduate School of Science, Division of Biological Science, Nagoya University)
Comment()

[1P-271]Entamoeba histolytica intermediate subunit lectin-1 is a β-N-acetylgalactosamine-recognizing monomeric lectin with a novel surface activity

○Kentaro Kato1,2, Koki Murata3, Yuri Kurogi3, Masahiro Wakao3, Yasuo Suda3, Hiroshi Tachibana4, Hiroyuki Shinchi3 (1. NEKKEN, Nagasaki Univ., 2. TMGH, Nagasaki Univ., 3. Grad. Sch. Sci. Eng., Kagoshima Univ., 4. Tokai Univ. Sch. Med.)
Comment()

[1P-272]Design of fluorescent immunosensors to minimize interference from autofluorescence in biological samples

○Shun Kagamihara1, Takanobu Yasuda2, Bo Zhu2, Tetsuya Kitaguchi2 (1. LST, Science Tokyo, 2. CLS, IIR, Science Tokyo)
Comment()

[1P-273]Tethered expression of TIMP2 on the cell surface enables the observation of its direct interaction with MMP13

○Nanami Nishijima1,2, Motomichi Doi1,2, Yoshio Kato1 (1. AIST, 2. University of Tsukuba)
Comment()

[1P-274]Study on the production of anti-human phosphorylated ASARM chicken-human chimeric antibody

○Yodai Kawanabe1, Ukyo Abe1, Tenkai Watanabe1, Mei Matsuzaki1, Ryo Ezaki1, Yuji Yoshiko2, Hiroyuki Horiuchi1 (1. Hiroshima University Graduate School of Integrated Sciences for Life, 2. Hiroshima University Graduate School of Biomedical and Health Sciences)
Comment()

[1P-275]Study on an adaptor protein that plays important roles in lymphangiogenesis

○Ayaka Inami1, Noriko Okuno1, Masanori Hirashima2, Katsuyoshi Takata1, Seiji Yamamoto1 (1. Department of Pathology, Academic Assembly Faculty of Medicine, University of Toyama, 2. Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University)
Comment()

[1P-276]Esterase with Enhanced Low-Temperature Activity Using a Directed Evolution Method.

○Kentaro Nakashima1, hazuki kurashita2, takashi ano1,2, masahiro okanami1,2 (1. Graduate School of Biology-Oriented Science and Technology, Kindai Univ. , 2. Biology-Oriented Science and Technology, Kindai Univ.)
Comment()

[1P-277(1MS-03-03)]Proteome-wide Correlation between Protein Half-Life and N-Terminal Acetylation by Bottom-up Proteomics

○Akane Takeshita1, Eisuke Kanao1,2, Koshi Imami3, Yasushi Ishihama1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NIBIOHN, 3. IMS, RIKEN)
Comment()

[1P-278]PAR1a can compensate for BRCA1 regulation by PAR1b only when PAR1b is dysfunctional from early embryogenesis

○Naoko Kamiya1, Adriana Alejandra Del Valle Lazarte2, Ippei Kikuchi3, Masanori Hatakeyama1,3 (1. Hokkaido Univ., 2. Univ. Tokyo, 3. Inst. Microbial. Chem.)
Comment()

[1P-279]Force measurement of the kinesin-3 motor KIF1A using DNA origami nanospring

○Nobumichi Takamatsu1,2, Hiroko Furumoto3, Takayuki Ariga4, Mitsuhiro Iwaki4,5,6, Kumiko Hayashi1,2 (1. ISSP, The Univ. of Tokyo, 2. The Univ. of Tokyo, 3. Yamaguchi Univ., 4. The Univ. of Osaka, 5. NICT, 6. IFReC, The Univ. of Osaka)
Comment()

[1P-280]Construction of target-directed liposomes by lipid modification of proteins based on a reconstituted cell-free protein synthesis system

○Rena Matsumoto1, Tatsuya Niwa2, Kaori Kuno3, Yasuhiro Shimane3, Yutetsu Kuruma3, Takashi Kanamori1 (1. GeneFrontier Corp., 2. CBC, IIR, Science Tokyo, 3. X-star, JAMSTEC)
Comment()

[1P-281]Designing PPR–RNA Interactions for Huntington’s Disease Therapy via Thermodynamic and Kinetic Profiling

○Yuna Yamazaki1, Yusuke Yagi2, Takamasa Teramoto1, Takahiro Nakamura1 (1. Faculty of Agriculture, Kyushu University, 2. EditForce, Inc.)
Comment()

[1P-283]Profiling proteins that function in oxidized or reduced form in plant ~Taking wound response as an example~

○Nagisa Sugiura1, Kohei Sato2, Saori Miyazaki2 (1. Shizuoka Univ. , 2. Shizuoka Univ.)
Comment()

[1P-284]Endonuclease inhibitor as a key to unlocking the PA-X shutoff mechanism in influenza A virus

○Kohei Oishi1, Kaori Sano2, Hideki Hasegawa2, Hideki Ebihara1 (1. National Institute of infectious diseases, Division of Virology I, 2. National Institute of infectious diseases, Influenza research center)
Comment()

[1P-285]PGRN-Dependent Regulation of Autophagy Under Cellular Stress in Neuronal Cells

○Bojun Wang1, Yuebo Shen1, Kasai Yuzuki1, Taku Nedati1 (1. Toyo University)
Comment()

[1P-286]Dual PI3P-binding and Rab5-induced dynamics of EEA1 revealed by HS-AFM

○Tareg Omer Mohammed1, Prem Kumar Viji Babu1, Shingo Fukuda1, Toshio Ando1 (1. Kanazawa University, Nano Life Science Institute (WPI-NanoLSI))
Comment()

[1P-287]Novel cellular phenotypes arising from overexpression

○Shotaro Namba1, Hisao Moriya1 (1. Okayama University)
Comment()

[1P-288]Attenuation of mitochondrial respiration improves thermotolerance in fission yeast

○Amelia Cheng Wei Tan1, Hayato Hirai2,3, Kunihiro Ohta2, Yukiko Nakase1,4, Kazuhiro Shiozaki1,5, Yuichi Morozumi1,6 (1. Div. Bio. Sci., NAIST, 2. Dept. of Life Sci., The Univ. of Tokyo, 3. Dept. of Basic Med. Sci., Tokyo Metropolitan Inst. of Med. Sci. , 4. Bio. and Life Sci., Yamato University, 5. Dept. of Microbiol. and Mol. Genet., UC Davis, 6. The Inst. of Enology and Viticulture, Univ. of Yamanashi)
Comment()

[1P-289]Cell-Adhesive Biomaterials Based on Multiple Recombinant Mussel Adhesive Proteins

○Wu Qiao1, Tong Xie1, Tinghan Jia1, Kaku Ken1 (1. PIGEON MANUFACTURING (SHANGHAI) CO.,LTD.)
Comment()

[1P-290]Directed exploration of protein interaction sequence space reveals the role of binding availability for interaction strength

○Pascale lemieux Lemieux1,2,3,4, Alexandre K Dubé1,2,3,4, Christian R Landry1,2,3,4,5,6 (1. Institut de Biologie Intégrative et des Systèmes (IBIS), 1030 avenue de la Médecine, Université Laval, Québec (Québec), Canada, G1V 0A6, 2. Regroupement Québécois de Recherche sur la Fonction, l’Ingénierie et les Applications des Protéines, (PROTEO), 1045 Avenue de la Médecine, Université Laval, Québec (Québec), Canada, G1V 0A6, 3. Centre de recherche en données massives (CRDM), 1065 avenue de la Médecine, Université Laval, Québec (Québec), Canada, G1V 0A6, 4. Département de biochimie, microbiologie et bio-informatique, 1045 Avenue de la Médecine, Université Laval, Québec (Québec), Canada, G1V 0A6, 5. Institut intelligence et données, 1065 Av. de la Médecine, Université Laval, Québec, (Québec), Canada G1V 0A6, 6. Centre de recherche en infectiologie, 2705 Boulevard Laurier, Université Laval, Québec (Québec), Canada G1V 4G2)
Comment()

[1P-291]Prediction of Sequence-Dependent Cleavage Efficiency for Proteases using Protein Language Model

○Yinghui Yang1, Bo Zhu2, Keisuke Mizutani3, Ken Kobayashi3, Takanobu Yasuda2, Tetsuya Kitaguchi2 (1. LST, Science Tokyo, 2. CLS, IIR, Science Tokyo, 3. IEE, Science Tokyo)
Comment()

[1P-292]PTM-directed high-resolution plasma proteomics uncovers system-wide alteration of protein acetylation associated with Alzheimer's Disease

○Hiroko Kozuka-Hata1, Aya Kitamura1, Tomoko Hiroki1, Naoaki Miyamura1, Kouhei Tsumoto1,2, Masaaki Oyama1 (1. Med. Proteomics Lab., Inst. of Med. Sci., Univ. of Tokyo, 2. Dept. of Bioeng., Grad. Sch. of Eng., Univ. of Tokyo)
Comment()

[1P-293]CD9-derived non-cationic peptide enables intracellular delivery of genome-editing protein Cas9

○Haruna Tadayasu1, Taiga Yokoi1, Yuko Yonemura1, Mayuko Ide1, Kei Fujiwara1, Nobuhide Doi1 (1. Keio University)
Comment()

[1P-295]The Dual Nature of Ligation and Degradation: Understanding and Controlling the Reverse Reaction of T4 RNA Ligase 1

○Nozomi Adachi1, Wataru Takahagi2, Shohei Terazawa1, Nao Masuda2, Ryoji Abe1, Kosuke Fujishima2,3 (1. LST., Science Tokyo, 2. ELSI., Science Tokyo, 3. Grad.sch. of Media and Governance., Keio Univ.)
Comment()

[1P-296]Interaction analysis of the C-terminal intrinsically disordered region of Mycobacterial DNA-binding protein 1 (MDP1) with flavonoids by using NMR.

○Ayaka Asai1, Natsuko Goda1, Tenno Takeshi1,2, Hibino Emi1, Nishiyama Akihito3, Ito Kosuke4, Matsumoto Sohkichi3, Hiroaki Hidekazu1,2,5 (1. Grad. School of Pharm. Sci., Nagoya univ., 2. BeCellBar, 3. Grad. School of Med and Dent Sci., Niigata univ., 4. Grad. School of Sci and Tech., Niigata univ., 5. NU-COMIT)
Comment()

[1P-297]Function and Structure of Clock-related Protein Kbl

○Shogo Ikezawa1, Risa Mutoh1 (1. Toho Univ.)
Comment()

[1P-298]Establishment of an antigen production by using insect virus protein microcrystals

○Ren Tomita1, Yuki Nakahama1, Keiko Takaki1, Eiji Kotani1 (1. Kyoto Institute of Technology)
Comment()

[1P-299]Ligand-binding analysis of the ancestrally reconstructed taste receptor type 1

○Nanami Kitamura1, Naotaka Tsutsumi1, Hidenori Nishihara2, Yasuka Toda3, Qiaoyi Liang4, Maude Baldwin4, Atsuko Yamashita5 (1. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2. Faculty of Agriculture, Department of Advanced Bioscience, Kindai University, 3. School of Life Science and Technology, Institute of Science Tokyo, 4. Max Planck Institute, 5. Institute for Protein Research, The University of Osaka)
Comment()

[1P-300]RNF128 regulates the adaptive metabolic response to fasting by modulating PPARα function

○YING CHUAN CHEN1, Yu Lung Lin1, Pei Yao Liu1 (1. Department of Physiology and Biophysics; Graduate Institute of Physiology, National Defense Medical Center.)
Comment()

[1P-302]α-Amylase plays a role in glycogenolysis in the skeletal muscles of older adults

○Tohru Hosoyama1, Minako Kawai-Takaishi1,2, Takuya Urushihata3,4, Akiko Satoh3,4, Tsuyoshi Watanabe5, Marie Takemura5, Daichi Shigemizu6,7, Keisuke Sekine8, Shosuke Satake9 (1. NCGG, Dept. Musculoskeletal Disease, 2. JSPS, 3. Tohoku Univ., IDAC, 4. NCGG, Dept. of Integrative Phys., 5. NCGG, Ctr. for Locomotive Syndrome & Frailty, 6. NCGG, Dept. of Bioinformatics, 7. Hiroshima Univ., Graduate School of Medicine, 8. NCC, Lab. of Cancer Cell Systems, 9. NCGG, Dept. of Frailty)
Comment()

[1P-303]New antibodies and ELISA system for Neuropeptide F immunostaining and detection

Tomoe Kobayashi1, Maki Higashida2, Ryusuke Niwa3, ○Makoto Matsuyama1 (1. Shigei Med. Res. Inst., 2. Univ. Tsukuba, Degree program, 3. Univ. Tsukuba, TARA)
Comment()

[1P-304]The effects of PM2.5 and PM10 exposure on the metabolomic profile of developing zebrafish

○Theerachat Kampaengsri1, Meng Chieh Yang1, Arnatchai Maiuthed1, Chanon Jakakul1, Chamnan Yibcharoenporn1 (1. Mahidol University)
Comment()

[1P-305]Analysis of the novel O-glycoprotease from Comamonas testosteroni

○Shou Takashima1, Masaki Kurogochi1, Daisuke Fujinami2, Shogo Nakano2, Sohei Ito2, Mamoru Mizuno1, Yoshio Takada1 (1. The Noguchi Institute, 2. Food and Nutritional Sciences, Univ. of Shizuoka)
Comment()

[1P-306]Isolation of High PHB-Producing Strains and Optimization of PHB Production Conditions Using the high temperature-adapted evolved E.coli Strain

○Waka Makino1, Miwa Kimura2, Noriko Kobayashi2, Miki Hashimoto2, Fugo Ube1, Makoto Kashima1, Ken'ichiro Matsumoto3, Toshihiko Kishimoto1 (1. Grad. Biomol. Sci., Fac. Sci., Toho Univ., 2. Dept. Biomol. Sci., Fac. Sci., Toho Univ., 3. Grad. Sch. Eng., Hokkaido Univ.)
Comment()

[1P-307]Artificial Intelligence-Assisted Analysis of Bioactive Components and Therapeutic Efficacy of Plant-Extracellular Vesicles in Wound Healing

○Qiao Jing Yan1, Qiang Fu1, Dan Zhong1, Jian Yao2, Yu Ping Fan3 (1. Jinggangshan University, 2. Yamanashi University, 3. Southeast University)
Comment()

[1P-308]DeepSeek-Proteomics Strategy Reveals Molecular Targets for IBD and Inflammation-to-Cancer Transition

○yu ping Fan1, Qiao Jing Yan3, qin Shen2, Yi Wen Yu1 (1. Southeast University, 2. Nanjing Municipal Hospital of Traditional Chinese Medicine, 3. Jinggangshan University)
Comment()

[1P-309]ACAT inhibition arrested the cell cycle in melanoma cells at the G1 phase by inhibiting the SREBP1/Cyclin D1 pathway

○Sayumi Yumoto1, Yasuomi Urano1, Noriko Noguchi1 (1. Graduate School of Life and Medical Sciences, Doshisha University)
Comment()

[1P-310]Lipid Profiling of EVs derived from Muse Cells

○Yuko Iwasaki1, Daisuke Ando1, Eiji Hishinuma2,3, Naomi Matsukawa2,3, Sherif Reashad1,4, Kuniyasu Niizuma1,3,4 (1. Tohoku University Graduate School of Medicine, 2. Tohoku Medical Megabank Organization, Tohoku University, 3. Innovations in Next-Generation Medicine, Tohoku University, 4. Graduate School of Biomedical Engineering, Tohoku University)
Comment()

[1P-311]Bioinformatics Analysis of Archaetidylserine Decarboxylase from the Halophilic Archaeon Halovivax ruber

○Yuzuki Kato1, Kaori Suzuki1, Naoki Nemoto1 (1. Chiba Institute of Technology)
Comment()

[1P-312(1MS-13-04)]Functional conservation of DNA repair proteins during vertebrate evolution

Julius Bannister1, Matthew Fawkes1, Samuel Jones1, ○Andrew Blackford1,2 (1. Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, UK, 2. Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark)
Comment()

[1P-313]Chromosome-level assemblies of Rhodotorula toruloides reveal abnormal chromosome rearrangement under artificial culture

○Yuuki Kobayashi1, Naoto Tanaka2, Keita Aoki1, Moriya Ohkuma3, Masako Takashima1 (1. Res. Ins. Agr. Life Sci., Tokyo Univ. Agr., 2. Fac. Life Sci., Tokyo Univ. Agr., 3. JCM, RIKEN)
Comment()

[1P-314]Prediction of Optimal Temperature Based on the Molecular Mechanism of Adenylate Kinase 1 Adapted to Body Temperatures in Chordates

○Tatsuya Yamamoto1, Azumi Wada1, Honoo Satake1 (1. Suntory Foundation for Life Sciences)
Comment()

[1P-315(1MS-13-02)]PD-1-mediated immune checkpoint system is conserved from sharks to humans

○Ryohei Kondo1, Kohei Kondo2, Kei Nabeshima3, Akihiko Nishikimi1, Yasumasa Ishida4, Toshiaki Shigeoka4, Johannes M. Dijkstra5 (1. National Center for Geriatrics and Gerontology, 2. Japan Institute for Health Security, 3. National Institute for Environmental Studies, 4. Nara Institute of Science and Technology, 5. Fujita Health University)
Comment()

[1P-316]Adaptive laboratory evolution of Corynebacterium glutamicum lacking the enzymes involved in the oxidation of NADH

○Shogo Nakabori1, Hazuki Kotani2, Satoru Fukiya1, Chikara Furusawa2,3, Michael Bott4, Tomoya Maeda1,2 (1. Hokkaido Univ. , 2. RIKEN, 3. Tokyo Univ., 4. Forschungszentrum Jülich)
Comment()

[1P-317(1AS-15-05)]Mapping evolutionary variants that drive human specific gene expression changes

○YIZHI YAN1,2, Nadav Mishol3, Katharina Lange3, Simon Fishilevich3, Zicong Zhang1, Omer Ronen3, Rika Tsujikawa1, Bourque Guillaume1,2,4, David Gokhman3, Fumitaka Inoue1 (1. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan, 2. Department of Human Genetics, McGill University, Montréal, Québec, Canada, 3. Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot, Israel, 4. Canadian Center for Computational Genomics, McGill University, Montréal, Québec, Canada)
Comment()

[1P-318]Short-read data capture ongoing structural dynamics of the chloroplast genome

○Eranga Pawani Witharana1, Yukio Nagano1,2,3,4 (1. The United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima, Japan, 2. Faculty of Agriculture, Saga University, Saga, Japan, 3. Vishnu Institute of Pharmaceutical Education & Research, Telangana, India , 4. Shri Vishnu College of Pharmacy, Andhra Pradesh, India)
Comment()

[1P-319]Rapid Evolution of Aminoacyl-tRNA Synthetases Using OrthoRep for Translational Reprogramming

○Yuichi Furuhata1,2, Chang C Liu2 (1. AIST MolBis, 2. UCI BME)
Comment()

[1P-320]Thermostable ancestral lysyl-tRNA synthetases suggest a thermophilic and autonomous lifestyle of the CPR last common ancestor

○Madoka Kimura1, Sota Yagi1,2, Satoshi Akanuma1 (1. Grad. Sch. Hum. Sci., Waseda Univ., 2. RIKEN IMS)
Comment()

[1P-321]Metal-dependent folding and RNA binding of proteins composed of a 10-amino acid set without cationic residue

○Fangzheng Zhao1, Satoshi Akanuma1, Sota Yagi2 (1. Fac. Hum. Sci., Waseda Univ., 2. RIKEN, IMS)
Comment()

[1P-322]Evolutionary Insights into the ASP Gene across HIV-1 and SIV Lineages

○Miu Naruki1,2, Asaka Yanada1, Motofumi Saito1, Shohei Nagata1, Hironori Sato4, Akio Kanai1,2,3 (1. Institute for Advanced Biosciences, Keio University, 2. Systems Biology Program Graduate School of Media and Governance, Keio University, 3. Department of Environment and Information studies, Keio University, 4. National Institute of Infectious Diseases)
Comment()

[1P-323]Origin and Accelerated Evolution of the Red Blood Cell Membrane Protein ACKR1

○Daigo Uramoto1, Takashi Kitano1 (1. Graduate School of Science and Engineering, Ibaraki University)
Comment()

[1P-324]Evolutionary analysis of wide range of primate-derived Ntcps and their susceptibility to hepatitis B and D virus

○Junko S Takeuchi1,2, Kaho Shionoya3, Coco Okamura1,2, Koichi Watashi3 (1. JIHS, CCS, 2. Toho Univ., 3. JIHS, NIID)
Comment()

[1P-325]Making deep mutational scanning accessible: a cost-efficient approach to construct barcoded libraries for genes of any length

○Jessica Jann1,2,3,4, Isabelle Gagnon-Arsenault1,2,3,4, Alicia Pageau1,2,3,4, Alexandre K Dubé1,2,3,4, Anna Fijarczyk1,2,3,4, Romain Durand1,2,3,4, Christian R Landry1,2,3,4 (1. Département de biochimie, de microbiologie et de bio-informatique, Faculté des sciences et de génie, Université Laval, G1V 0A6, Québec, Canada, 2. Institut de biologie intégrative et des systèmes, Université Laval, G1V 0A6, Québec, Canada, 3. PROTEO, Le regroupement québécois de recherche sur la fonction, l’ingénierie et les applications des protéines, Université Laval, G1V 0A6, Québec, Canada, 4. Centre de recherche sur les données massives, Université Laval, G1V 0A6, Québec, Canada)
Comment()

[1P-326]Design of a Simple and Flexible Tool for Sequence Alignment Visualization

○Miki Okuno1, Takeshi Yamamoto1, Yoshitoshi Ogura1 (1. Kurume University)
Comment()

[1P-327]Ancient Genomic from the Nenggiri Valley: Insights into Prehistoric Populations and Malay Peninsula Indigenous Groups

○AHMAD FAIZ SHAZWAN BIN ABDUL MALIK1, 2.Odongoo Ravdandorj2, 3.Zuliskandar Bin Ramli3, Dato' Dr. Mohd Zaki Salleh4, Lay Kek Teh5, Takashi Gakuhari6 (1. Graduate School, Human and Socio-Environmental Studies, Humanities Major, Special Program of Archaeology, Kanazawa University, 2. Sapiens Life Sciences, Evolution and Medicine Research Center, Kanazawa University, 3. Institute of the Malay World and Civilization, The National University of Malaysia, 4. Director Zakesy Biotech Sdn Bhd. Malaysia, 5. Faculty of Pharmacy, UiTM Puncak Alam, Malaysia , 6. Institute for the Study of Ancient Civilizations and Cultural Resources, Kanazawa University)
Comment()

[1P-328]Snakes encode Arf-Ink4a chimeric protein

Konno Reina1, Shouguo Zhang1, Feng Wen1, Kohshirou Ono1, Yukitoshi Nakama2, Koki Terada2, Shiori Yuki1, ○Isato Araki1 (1. Iwate Univ, 2. Okinawa Prefectural Institute of Health and Environment)
Comment()

[1P-329]Haplotype resolved genome assembly and regional comparative analysis of Patiria pectinifera

○Ryoma Sugiyama1, Kazunori Tachibana1, Atsushi Toyoda2, Takehiko Itoh1 (1. Institute of Science Tokyo, 2. National Institute of Genetics)
Comment()

[1P-330]Phospholamban-Targeting Aptamers with Efficient Intracellular Delivery into Cardiomyocytes

○Takeshi Honda1, Hiroki Sakai2, Makoto Inui3 (1. Kurume Univ., 2. Institute of Cetacean Research, 3. YIC Rehabilitation College)
Comment()

[1P-331]Temozolomide-resistant glioblastoma cells acquire promoted migratory potential via activation of MMP2 and MMP9

○Hien Thanh Duong1, Thang Huu Nguyen2, Chaeyong Jung1 (1. Department of Anatomy, Chonnam National University Medical School, Gwangju 61469, Korea, 2. Department of Biochemistry, Chonnam National University Medical School, Gwangju 61469, Korea)
Comment()

[1P-332]Novel regulatory mechanisms of the association between the tumor suppressor PP2A and its inhibitory protein PME-1

○Sana Ando1, Hinako Ueno2, Takashi Ohama1,2 (1. Yamaguchi Univ. Joint Graduate School of Vet. Med., 2. Yamaguchi Univ. Joint Faculty of Vet. Med.)
Comment()

[1P-334(1AS-01-05)]From Materials to Metabolism: Deep-Layer Multi-Omics Reveals Hidden Biocompatibility Signatures

○Hiroyuki Okada1,2, Shohei Ishikawa3, Masaru Mori4, Akiyoshi Hirayama5, Yoshiaki Kitaura1, Asuka Terashima6, Yasunori Omata6,2, Ung-il Chung1,7, Kazuharu Arakawa5, Keiji Numata8,5,9, Takamasa Sakai3, Hironori Hojo1,7 (1. Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the Univ. of Tokyo, 2. Dept. of Orthopaedic Surgery, the Univ. of Tokyo, 3. Department of Chemistry and Biotechnology, Graduate School of Engineering, the Univ. of Tokyo, 4. Institutes of Innovation for Future Society, Nagoya University, 5. Institute for Advanced Biosciences, Keio University, 6. Bone and Cartilage Regenerative Medicine, the Univ. of Tokyo Hospital, 7. Department of Bioengineering, Graduate School of Engineering, the Univ. of Tokyo, 8. Department of Material Chemistry, Graduate School of Engineering, Kyoto Univ., 9. Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science)
Comment()

[1P-335]Inhibition of lncRNA LinP1 Overcomes Chemoresistance in Triple-Negative Breast Cancer

○Yun Cen Chen1, Hung Ting Lin1, Han Tsang Wu1, Dar Ren Chen1,2 (1. Cancer Research Center, Department of Research, Changhua Christian Hospital, Changhua 500, Taiwan, 2. Comprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua 500, Taiwan)
Comment()

[1P-336]Impact of Verteporfin on YAP/TAZ Signaling and Adipogenesis in 3T3-L1 Preadipocytes

○Ya-Chi Chan1, Jhih-Wen Hsu1, Chia-Lin Wu1, Chung-Ho Chang2 (1. Renal medicine Laboratory, Changhua Christian Hospital, Changhua, Taiwan , 2. Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli County, Taiwan)
Comment()

[1P-337]Simultaneous Prediction of Multiple Drug-Target Binding Affinities with 3D-aware Deep Learning

○Akinori Kawaharada1, Hideyuki Shimizu2,3 (1. Professional Development Center, Division of Clinical Management, Institute of Science Tokyo Hospital, 2. Department of AI Systems Medicine, M&D Data Science Center, Institute of Integrated Research, Institute of Science Tokyo, 3. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-338]Reliable Extraction and Visualization of Immunohistochemistry Protocols Using Large Language Models

○Kohei Koike1, Ryohei Chihara1, Tadahiro Hoshino1, Yuri Komazawa1, Naoto Komatsu1 (1. Mobius Co., Ltd., Bioscience Unit)
Comment()

[1P-340]Effect of 265 nm UV Irradiation on Coagulation Factor Activity: Correlation With Amino Acid Composition

○Tomoya Hayashi1, Yoshihiro Fujimura1, Yuichi Mishima2, Kumiko Oguma3, Mikako Masaki1, Akihiro Fuchizaki1, Kazuta Yasui1, Yoshihiko Sakurai4, Hiroyuki Ishii1, Yoshihiko Tani2, Takafumi Kimura1 (1. Japanese Red Cross Society Kinki Block Blood Center, 2. Japanese Red Cross Society Blood Service Headquarters Central Blood Institute, 3. The University of Tokyo Graduate School of Engineering, 4. Nara Red Cross Blood Center)
Comment()

[1P-341]Correlating Lecture and Laboratory Class Performance in Undergraduate Biochemistry Education

○FAI HANG LO1 (1. THE CHINESE UNIVERSITY OF HONG KONG)
Comment()

[1P-343]CD200 enhances gastric tumor cell proliferation and motility through β-catenin pathway activation and induction of EMT

○Hana Lee1,2, Seok-Jun Kim1,2,3 (1. Department of Integrative Biological Sciences & BK 21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, Republic of Korea , 2. Institute of Well-Aging Medicare & Chosun University G-LAMP Project group, Chosun University, Gwangju, Republic of Korea, 3. Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea)
Comment()

[1P-345]Multi-layered and reversible phospho-regulation of condensin I drives chromosome morphogenesis throughout mitosis

○Keishi Shintomi1, Yuki Masahara-Negishi1, Shoji Tane1, Tatsuya Hirano1 (1. RIKEN)
Comment()

[1P-346]Triplex nucleic acid recognition mechanism of triplex nucleic acid-binding proteins and its application to artificial regulation of target gene expression

○Riyou Shinoda1, Maiko Shimmura1, Mayu Sutoh1, Kazuki Kiuchi1, Takuma Katayama1, Hidetaka Torigoe1 (1. Dept. Chem., Grad. Sch. Science, Tokyo Univ. Sci.)
Comment()

[1P-347]An artificial CENP-N oligomerization approach to reveal the role of CENP-C in CCAN assembly in DT40 cells

○Ai Hoshikawa1, Yusuke Takenoshita1, Tatsuo Fukagawa1 (1. FBS, The University of Osaka)
Comment()

[1P-348]Prediction of binding sites between condensinⅡ hCAP-D3 and PP2A-B55 using AlphaFold3, and analysis using hCAP-D3 mutant-expressing cells

○Shunsuke Arimoto1, Kazashi Kato1,2, Sae Higashiura1, Tomoaki Ishiba2, Kenji Iwasaki2, Keiji Kimura1,2 (1. Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba, 2. TARA)
Comment()

[1P-349(1AS-10-05)]Selective localization of Importin-α defines functional properties of micronuclei

○Yoichi Miyamoto1, Masahiro Oka2, Hisato Saitoh3, Toyomasa Katagiri1 (1. Lab. Biofunc. Mol. Med., Natl. Inst. Biomed. Innov., Health, Nut. , 2. Dept. Reg. Infect. Cancer, Res. Inst. Micrb. Dis., Osaka Univ. , 3. Faculty Adv. Sci. Tech. (FAST), Kumamoto Univ.)
Comment()

[1P-350(1PS-06-06)]Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

○Takao Ono1, Masatoshi Takagi2,6, Hideyuki Tanabe3, Tomoko Fujita4, Noriko Saitoh4, Akatsuki Kimura5, Tatsuya Hirano1 (1. Chromosome Dynamics Laboratory, RIKEN, , 2. Cellular Dynamics Laboratory, RIKEN, , 3. Research Center for Integrative Evolutionary Science, The Graduate University for Advanced Studies, SOKENDAI, 4. Division of Cancer Biology, The Cancer Institute of JFCR, 5. Department of Chromosome Science, National Institute of Genetics, National Institute of Genetics, 6. Present address: Laboratory for Cell Function Dynamics, RIKEN Center for Brain Science)
Comment()

[1P-351]Analysis of the selective loss mechanism of co-expression plasmids for heterologous proteins in budding yeast

○Tatsuki Kenmochi1, Takeshi Nakamoto2, Shiori Tobinaga1, Noriyuki Suka1,2 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Prog. in Chem. Life Sci., Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan)
Comment()

[1P-353]Loss of expression of foreign stress proteins in budding yeast depending on the local environment of the plasmid

○Yuzuki Nara1, Koki Kusuda1, Shiori Tobinaga1, Noriyuki Suka1 (1. MEISEI University)
Comment()

[1P-354]Mechanisms of double-strand break control in C. elegans

○Keita Kameda1, Tasha Melvin1, Meng Lin1, Aya Sato1, Peter Carlton1 (1. Kyoto university)
Comment()

[1P-355]Roles of nucleolus and AS2 bodies in leaf development

○Chiyoko Machida1, Hidekazu Iwakawa2, Ayami Nakagawa3, Sayuri Ando1, Rina Kawamoto1, Iwai Ohbayashi4, Munetaka Sugiyama5, Michiko Sasabe6, Yasunori Machida7, Shoko Kojima1 (1. Chubu University, 2. Kanazawa Univ., 3. Nagoya Univ. , 4. National Cheng Kung Univ., 5. Univ. of Tokyo, 6. Hirosaki Univ., 7. Nagoya Univ.)
Comment()

[1P-356]Regulation of perinuclear vesicule formation and Embryonic Development in Mouse Zygotes by Protein Kinase C

○Toru Suzuki1,2, Yuriko Sakamaki3 (1. Animal Research Facilities, Bioscience Center, Institute of Science Tokyo, 2. Laboratory of Genome Editing for Biomedical Research, Medical Research Laboratory, Institute of Science Tokyo, 3. Ochanomizu Research Facility (ORF), Bioscience Center, Institute of Science Tokyo)
Comment()

[1P-357]Proteins that target telomere loops for deprotection during mitosis

○Placide Niyonshuti1, Makoto Hayashi2,3 (1. Kyoto University , Graduate School of Biostudies , 2. IFOM-KU JRL, Graduate School of Medicine, Kyoto University, 3. Chromosome Instabilities Unit, IFOM ETS)
Comment()

[1P-358]Molecular mechanisms underlying sex differences in meiosis, in medaka (Oryzias latipes)

○Shiyu Kameyama1,2, Taiki Niwa3, Ryuki Shimada4, Kei-ichiro Ishiguro4, Ryota Sakata5, Tomoko Nishiyama5, Mariko Kikuchi1, Minoru Tanaka1 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Nagoya Univ., 2. Fisheries lab, Grad. Sch. of Agri., Tokyo Univ., 3. Lab. Molecular Life History, Genet., SOKENDAI, 4. Div. of Dev. Reg., Inst. of Mol. Embryol. and Genet., Kumamoto Univ., 5. Dept. of Biol. Sci., Grad. Sch. of Sci., Kyoto Univ.)
Comment()

[1P-359]Clustering mechanism and quality control of Nuclear Pore Complex under chronic heat stress in yeast

○Yu Onouchi1, Shota Shimizu1, Yoko Kimura1 (1. Applied Life Sciences, Grad. Sch. of Agr., Shizuoka Univ.)
Comment()

[1P-360]The role of ELYS during nuclear membrane reformation

○Kei Makiyama1, Richard Wing Wong2, Masaharu Hazawa3 (1. Division of Transdisciplinary Sciences, Graduate School of Frontier Science Initiative, Kanazawa University, 2. WPI Nano Life Science Institute, Kanazawa University, 3. Cell-Bionomics Research Unit, Institute for Frontier Science Initiative, Kanazawa University)
Comment()

[1P-362]A comprehensive search for proteins that prevent the transfer of droplets to disease aggregates

○Nanami Hirashita1, Eriko Mano1, Tatsuya Niwa2, Kiyoto Kamagata1 (1. Graduate School of Natural Science and Technology , Gifu Univ., 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
Comment()

[1P-364]Investigation of the G-body formation and regulation by Dorsomorphin in HepG2 cell line under hypoxia.

○HIROKO OGASAWARA1, MICHIHIKO KATAOKA1, NATSUKO MIURA1 (1. Dept. Appl. Biol. Chem., Grad. Sch. Agric., Osaka Metropolitan Univ.)
Comment()

[1P-365]In vitro analysis of protein dynamics involved in the formation of nuclear bodies

○Taro Mannen1, Yuki Sakurai1, Takuya Yoshizawa1, Hiroyoshi Matsumura1, Toshiya Hayano1 (1. Ritsumeikan University)
Comment()

[1P-366]Stress granules as a regulator of insulin secretion

○Kazunori Hashimoto1, Jun-ichi Miyazaki2, Satsuki Miyazaki2, Tomiyasu Murata1 (1. Meijo University, 2. Osaka Unviersity)
Comment()

[1P-367]Novel transcriptional regulators which showed osmotic stress-inducible phase separation were identified by iChIP, a screen method to isolate protein complexes on a specific promoter in planta

○Hikaru Sato1,2, Satoru Fujimoto3, Miki Fujita2, Fuminori Takahashi2, Keiko Kuwata4, Sachihiro Matsunaga1,3, Kazuko Yamaguchi-Shiniozaki5,6, Kazuo Shinozaki2 (1. Dept. of Integr. Biosci., Univ. Tokyo, 2. RIKEN CSRS, 3. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci., 4. ITbM, Nagoya Univ., 5. Grad. Sch. Agr. Life Sci., Univ. Tokyo, 6. Res. Inst. Agr. Life Sci., Tokyo Univ. Agr.)
Comment()

[1P-368]Cytoplasmic SF3A1 acts as a negative regulator of RNA granule formation

○Kyota Yasuda1,2,3, Rina Mihara1, Shin-ichi Tate1,3,2,5, Hyun-woo Rhee4 (1. Hiroshima University, 2. WPI-SKCM2, 3. RcMcD, 4. Seoul National University, 5. Meiji University)
Comment()

[1P-369]Regulatory Mechanism of the Disassembly Order of Multiphase Nucleolus During Mitosis

○Hisashi Shimamura1, Shige.H. Yoshimura1,2 (1. Kyoto Univ., 2. Kyusyu Univ.)
Comment()

[1P-370]A novel regulatory mechanism of nuclear proteostasis via Mahjong (Vprbp/DCAF1)

○TOMOKI KYO1, Naoka Shiratsuchi1, Sakurako Nozaki1, Riku Egami2, Kei Kozawa1, Yasuyuki Fujita1 (1. Department of Molecular Oncology, Graduate School of Medicine, Kyoto University, 2. Division of Molecular Oncology, Institute for Genetic Medicine, Hokkaido Universit)
Comment()

[1P-372]Vesicular Transport Pathways in the Mechanism of Long-Range Suppression of Notch Signaling

○Kosuke Nishi1, Tomoko Yamakawa1 (1. National Institute of Technology (KOSEN), Ibaraki College)
Comment()

[1P-373]Translocation of nuclear LC3 is associated with serum starvation and cell cycle dynamics

○Nattanicha Wuttitanuthong1, Kumpanat Pomlok2, Pathrapol Lithanatudom3 (1. Master Degree in Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand, 2. Department of Microbiology, Faculty of Science, Silpakorn University, Nakhon Pathom, 73000, Thailand, 3. Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand)
Comment()

[1P-374]Proximity labeling-based analysis of KPNA/Importin a interactome in neurons.

○Hiro Shibata1, Katsutoshi Mizuno1,2, Takafumi Itoh3, Masami Yamada1,2 (1. Faculty of Medical Sciences, University of Fukui, 2. Life Science Innovation Center, University of Fukui, 3. Graduate School of Bioscience and Biotechnology, Fukui Prefectural University)
Comment()

[1P-375]Identification of a novel amino acid to control the nuclear translocation of PTEN

○Takashi Kato1, Suzu Tanaka1 (1. Yasuda Women's University)
Comment()

[1P-377]β2microglobulin-independent cell surface expression of HLA class I heavy chains and their molecular characterization

○Shigeki Aoki1, Mai Nonaka1, Keitaro Umezawa2, Yuri Miura2, Kousei Ito1 (1. Chiba Univ., 2. TMIG)
Comment()

[1P-380]Mechanism of axon regeneration mediated by intracellular communication via extracellular vesicles

○Mikiya Takai1, Tatsuhiro Shimizu1, Kunihiro Matsumoto1, Naoki Hisamoto1 (1. Nagoya Univ.)
Comment()

[1P-381]Temporal analysis of G-body formation in quiescent cancer cell model

○TERI GELE1, Kotaro Miyamoto1, Ning Lin1, Miura Natsuko2, Kadonosono Tetsuya1 (1. Institute of Science Tokyo, 2. Osaka Metropolitan University)
Comment()

[1P-382]Analysis of the Effect of N-linked Glycan Modification in the Golgi Lumen on Endocytosis in Budding Yeast

○Hiroki Shimamura1, Tadashi Omori1, Makoto Nagano2, Junko Nagano3, Jiro Toshima1 (1. Department of Biological Science and Technology, Tokyo University of Science, 2. Nat. Inst. of Infect. Dis. Center, 3. Sch. of Heal. Sci., Tokyo Univ. of Tech.)
Comment()

[1P-383]The effect of cationic amphiphilic drug on endocytosis pathway

○Shuto Akino1, Natsuki Shima1, Hiroki Shimamura1, Makoto Nagano1,2, Junko Toshima1,3, Jiro Toshima1 (1. Tokyo Univ. of Sci, 2. NIID, 3. Tokyo Univ. of Tech)
Comment()

[1P-384]Role of retrograde transport in the formation of sorting compartments in the endocytosis pathway

○Miyu Inoue1, Nagisa Tsuchida1, Honoka Suyama1, Hiroki Shimamura1, Makoto Nagano1,2, Junko Y Toshima1,3, Jiro Toshima1 (1. Dept. of Bio. Sci. and Tech., Tokyo Univ. of Sci., 2. Drug Vac., NIID., 3. Institute of Physical and Chemical Research.)
Comment()

[1P-385]Analysis of the effects of abnormalities in the endocytic pathway on secretory and recycling pathways

○Keitaro Yamamoto1, Koya Nukaga1, Hiroki Shimamura1, Makoto Nagano2,1, Junko Toshima3,1, Jiro Toshima1 (1. Tokyo University of science, 2. Drug Vac., NIID, 3. Sch. of Heal. Sci., Tokyo Univ. of Tech)
Comment()

[1P-386]Effect of deletion of yeast PI3 kinase Vps34p on the vesicle transport between the TGN and endosome

○Honoka Suyama1, Nagisa Tuchida1, Miyu Inoue1, Ririko Kurihara1, Hiroki Simamura1, Junko Toshima2,1, Makoto Nagano3,1 (1. Tokyo University of Science, 2. Tokyo University ofTecnology, 3. National Institute of infectious Deseases)
Comment()

[1P-387(3AS-01-09)]Precision Control of Organelles and Cellular Functions via Copper-Free DBCO–Azide Click Chemistry

○Takayuki Seki2, Kanata Itadoko2, Koutaro Shiwa3, Kazunobu Igawa3,4, Hisato Saitoh1,4,2 (1. Department of Biological Science, Graduate School of Science and Technology(GSST), Kumamoto University, 2. Faculty of Science, Biological Science, Kumamoto University, 3. Department of Chemistry, Graduate School of Science and Technology(GSST), Kumamoto University, 4. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
Comment()

[1P-388]Engineering Light-Driven Metabolism in Vertebrates: Reimagining Kleptoplasty Using Medaka Fish

○Lilingman Fan1, Wataru Kawamura2, Natsuki Hara1, Rinka Isayama3, Keiichiro Hyakutake4, Ko Eto1,2,3, Takeshi Kitano1,2,3, Hisato Saitoh1,2,3 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University, 3. Faculty of Science, Biological Science, Kumamoto University, 4. Open Innovation Center, Kumamoto University, Kumamoto)
Comment()

[1P-389]Cellular Strategies for Coping with Organelle Stress During Kleptoplasty

○Natsuki Hara1, Lilingman Fan1, Rinka Isayama2, Ayana Tokuda2, Kanata Itadoko2, Hisato Saitoh1,2,3 (1. Graduate School, Kumamoto University, 2. Faculty of Science, Kumamoto University, 3. Faculty of Advanced Science and Technology, Kumamoto University)
Comment()

[1P-390(2MS-15-03)]"The Multifunctionality of the Plant Biomineral Raphide: Carbon Sequestration and Physiological and Medical Applications"

○Kazutaka TASHIMA1, Hisato Saitoh2,1 (1. Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kumamoto, Japan, 2. Faculty of Advanced Science and Technology, Kumamoto University, Kumamoto, Japan)
Comment()

[1P-391]Actin and Importin-α as Regulators of Nuclear Organelle Miniaturization and Heterogeneity: A Newly Identified Mechanism

○Yuto Suetsugu1, Yoichi Miyamoto2, Hisato Saitoh1,3 (1. Department of Biological Science, Graduate School of Science and Technology(GSST),Kumamoto University, 2. Laboratory of Biofunctional Molecular Medicine National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), 3. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
Comment()

[1P-392]Analysis of autophagy and mitochondrial degradation mechanisms mediated by TOR signaling in the ciliate Tetrahymena.

○Shinya Matsuda1, Kentaro Nakano2 (1. Osaka Metropolitan Univ., 2. Univ. of Tsukuba)
Comment()

[1P-393]Selective autophagy of organelles during meiosis in S. pombe

○Mayu Tanimoto1, Yuya Kadowaki1, Haruka Uda1, Goji Miyasako2, Sayumi Yamashita1, Akio Nakashima1,2,3 (1. Graduate School of Agricultural Science, Kobe University, 2. Faculty of Agriculture, Kobe University, 3. Biosignal Research Center, Kobe University)
Comment()

[1P-394]Messenger RNA-Encoded Reporters for Monitoring Cellular Stress and Bioenergetics

○Karen Kai-Lin Hwang1,2, Qi Fang1, Carine Nizard3, Anne-Laure Bulteau3, Knut Woltjen1 (1. Center for iPS Cell Research and Application (CiRA), Kyoto University, 2. Graduate School of Medicine, Kyoto University, 3. LVMH Recherche, Parfums Christian Dior)
Comment()

[1P-395]Redox Crosstalk Between Glutathione and Hydrogen Peroxide in the Endoplasmic Reticulum

○Runa Zamma1, Hiroki Watanabe1, Chika Tsutsumi1,2, Ryo Ushioda1,2 (1. Graduate school of Life Sciences, Kyoto Sangyo Univ., 2. Institute For Protein Dymamics, Kyoto Sangyo Univ.)
Comment()

[1P-396]Comparative Analysis of Mitochondria from Sperm and Fertilized Eggs in Caenorhabditis elegans

○Taeko Sasaki1, Takuya Norizuki1, Hidetaka Kosako2, Ken Sato1, Miyuki Sato1 (1. IMCR, Gunma University, 2. IAMS, Tokushima University)
Comment()

[1P-397]Molecular Mechanism of Microautophagy and the Role of Cysteine Proteases in Plants

○Shino Goto-Yamada1,2,3, Kritika Bhardwaj2, Elżbieta Kaniecka2, Shoji Mano1,3, Kenji Yamada2 (1. Natl. Inst. Basic Biol., Lab. Org. Regul., 2. Jagiellonian Univ., MCB, 3. Graduate Univ. Advanced Studies, Basic Biol. Prog.)
Comment()

[1P-398(1AS-18-06)]Mechanism of ciliary compartmentalization by transition zone proteins.

○Hirone Kita1, Yuta Takahashi1, Kazumasa Ohashi1, Yohei Katoh2, Kazuhisa Nakayama2, Shuhei Chiba1 (1. Department of Physiological Chemistry, Graduate School of Life Science, Tohoku University., 2. Department of Physiological Chemistry, Graduate School of Pharmaceutical Science, Kyoto University.)
Comment()

[1P-399]PGC-1-related coactivator promoted mitochondrial biogenesis is crucial for motile cilia movement in Xenopus epidermis

○Kim Jihoon1, Teramoto Takayuki1, Okumoto Kanji1, Matsui Eisei1, Anchi Hiroyuki1, Imamura Arata1, Okano Naho1, Nakajo Nobushige1 (1. Kyushu Univ.)
Comment()

[1P-400]Towards understanding the dynamics of two types of secretory vesicles in pancreatic β cells

○Hiroyasu Hatakeyama1, Tomomi Oshima1, Hidekazu Fukuda1, Noriko Takahashi1 (1. Department of Physiology, Kitasato University School of Medicine)
Comment()

[1P-401]Exploring the key regulator that governs the glass-liquid transition of cytoplasm during germination of Dictyostelium spores

○Gen Honda1,2, Satoshi Sawai1,3, Miho Yanagisawa1,2,3 (1. Department of Basic Science, Tokyo Univ., 2. Komaba Institute for Science, Tokyo Univ., 3. Research Center for Complex Systems Biology, Tokyo Univ.)
Comment()

[1P-402]Development of objective mirror for cryogenic correlative light and electron microscopy of cells

○Tetsuya Yamakawa1, Takuma Yorita1, Kanta Naruse1, Michio Matsushita1, Satoru Fujiyoshi1 (1. Tokyo Institute of Science)
Comment()

[1P-403]Development of a novel tool, AID-RBD27 system that artificially regulates melanosome transport in melanocytes

○Akira Sugawara1, Yuto Maruta1, Mitsunori Fukuda1 (1. Lab. of Membr. Trafficking Mech., Grad. Sch. of Life Sci., Tohoku Univ.)
Comment()

[1P-404]Functional analysis of Rab30, a novel substrate candidate of TBC1D22B, in tubular endosome formation

○Shumpei Nakashima1, Mitsunori Fukuda1 (1. Tohoku Univ.)
Comment()

[1P-405]Deletion of the endoplasmic reticulum membrane protein Ilm1 causes lipid metabolic defects and aggregation of mitochondrial membrane proteins.

○Sota Yamada1, Shina Furuta1, Yasushi Tamura2 (1. Graduate School of Science and Engineering, Yamagata University, 2. Faculty of Science, Yamagata University)
Comment()

[1P-406]SBI115 suppresses glioblastoma growth and motility via cAMP/CREB and JAK2/STAT3 inhibition

○Ying Chen1, Ni Wei1 (1. Department and Graduate Institute of Biology and Anatomy, College of Medicine, National Defense Medical University)
Comment()

[1P-407]Molecular mechanisms of invadopodium maturation by Arf6 GTPase-Activating Protein ACAP

○Ryotaro Kodaira1, Xiaoying Jian2, Daisuke Okusaki3, Paul A. Randazzo2, Hiroki Inoue1 (1. Sch. Life Sci., Tokyo Univ. Pharm. Life Sci., 2. NIH / NCI, USA, 3. Immunol. Front. Res. Center, Osaka Univ.)
Comment()

[1P-408]Role of thrombin-cleaved nephronectin in metabolic dysfunction-associated steatotic liver disease (MASLD)

○Machiko Honda1, Shigeyuki Kon1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University Laboratory of Molecular immunology)
Comment()

[1P-409]Functional analysis of an olfactory receptor in mouse spermiogenesis

○Momoka Takatsu1, Katsuyoshi Takaoka2, Yosuke Fukutani1, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Tokushima University)
Comment()

[1P-410(1PS-07-07)]Spontaneous pattern formation through cell migration organized by extracellular matrix-producing chondrocytes

○Shogo Nakayama1, Masahito Mori2, Keishi Kishimoto1, Kyosuke Adachi1, Takumi Matsuura1, Kyogo Kawaguchi3,4, Mitsuru Morimoto1 (1. RIKEN BDR, 2. Department of Physics, University of Tokyo, 3. RIKEN Cluster for Pioneering Research, 4. Institute for Physics of Intelligence, University of Tokyo)
Comment()

[1P-411]Targeting CIP2A with ascofuranone inhibits metastasis via Myc degradation–mediated repression of Snail in colorectal cancer cells

Yun-Jeong Jeong1, ○Young-Chae Chang1 (1. Daegu Catholic University school of medicine)
Comment()

[1P-412]Annexin A2 localizes to adherens junctions in an actomyosin-dependent manner

○Souta Takeuchi1, Hiroaki Hirata2 (1. Dept. Biotech., Grad Sch. of Eng., Kanazawa Inst. Tech., 2. Dept. of Life Sci. & Biotech., Kanazawa Inst. Tech.)
Comment()

[1P-413]Exploration of cell competition regulators using artificial receptor synNotch

○Jiaying Wen1, Kazuhito Sai1, Suzuka Masutani1, Ken Mizuta2,3, Tomonori Nakamura2,3,4, Mitinori Saitou2,3,5, Satoshi Toda6, Yasuyuki Fujita1 (1. Department of Molecular Oncology, Graduate School of Medicine, Kyoto University, 2. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, 3. Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, 4. The Hakubi Center for Advanced Research, Kyoto University, 5. Center for iPS Cell Research and Application (CiRA), Kyoto University, 6. Institute for Protein Research, Osaka University)
Comment()

[1P-414]Regulation of cellular network formation using culture supernatants derived from various cell types

○Takako Koujin1, Shouhei Kobayashi1 (1. National Institute of Information and Communications Technology)
Comment()

[1P-415(1PS-12-02)]Actin Crosslinking Proteins Mediate Myosin Contractile Force Applied to Cell-Cell Adhesion

○Nobutomo Fujimoto1,2, Doan Manh2, Hiroki Katsuta2, Hiroaki Hirata3, Keiji Naruse2 (1. Okayama University, Medical School, 2. Okayama University, Department of Cardiovascular Physiology, 3. Kanazawa Institute of Technology, Department of Life Science and Biotechnology)
Comment()

[1P-416(1AS-06-07)]Characterization of Zonula occludens-1 in invadopodia

○Ngoc Phuong Pham1,2,3, Sayuki Hirano2, Kazuhiro Aoki2,3 (1. Basic Biology Program, Department of Advanced Studies, Graduate Institute for Advanced Studies, The Graduate University for Advanced Studies, SOKENDAI , 2. Laboratory of Cell Cycle Regulation, Graduate School of Biostudies, Kyoto University, 3. Center for Living Systems Information Science, Graduate School of Biostudies, Kyoto University)
Comment()

[1P-417]Considerations on EMT-related cell behaviors induced in A549 lung cancer carcinoma cells cultured on type I collagen gels 2025

○Hitomi Fujisaki1, Sugiko Futaki2, Kiyotoshi Sekiguchi3, Toshihiko Hayashi4, Shunji Hattori5 (1. Nippi Research Institute of Biomatrix, 2. Osaka Medical and Pharmaceutical Univ., 3. The University of Osaka, 4. Shenyang Pharmaceutical Univ., 5. MATRIXOME, Inc.)
Comment()

[1P-418(1AS-12-06)]Heterogeneous ECM remodeling regulates collective migration of epithelial cells

○Ayae Oshima1,2, Komaki Ninomiya2, Erina Kuranaga1,2 (1. Lab. of Organ Morphogenesis, Grad. Sch. of Life Sci., Tohoku Univ., 2. Lab. for Histogenetic Dynamics., Grad. Sch. of Pharm. Sci., Kyoto Univ.)
Comment()

[1P-419(1AS-06-05)]Macropinocytosis promotes collective cell migration by driving cell shape changes through membrane transport

○Kaede Nakasato1, Sayaka Sekine2,1, Mayuko Sato3, Satoko Okayama4, Kenta Onoue4, Shigenobu Yonemura4, Kiminori Toyooka3, Hiroyuki Uechi1,5, Erina Kuranaga1,5 (1. Lab. of Organ Morphogenesis, Grad. Sch. of Life Sci., Tohoku Univ, , 2. Science Tokyo, 3. RIKEN CSRS, 4. RIKEN BDR, 5. Lab. for Histogenetic Dynamics., Grad. Sch. of Pharm. Sci., Kyoto Univ.)
Comment()

[1P-420(1AS-06-06)]Vertex remodeling by PAK4 and Afadin maintains epithelial integrity and barrier function

○Tomohito Higashi1, Babli Adhikary2, Alexander Chang2, Atsuko Y Higashi1, Hideki Chiba1, Ann L Miller2 (1. Fukushima Medical University, 2. University of Michigan)
Comment()

[1P-421]Cell membrane phase change and raft formation during leukocyte adhesion

○Aoi Sumida1, Takanori Kihara1, Kouichi Tachibana2 (1. Univ Kitakyushu, 2. Univ Tokai)
Comment()

[1P-422]Elucidation of the physiological function of non-triple helical collagen polypeptide : Evaluation of cell migration-promoting activity using recombinant proteins

○Sui Kashiwagi1, Hiroto Tanaka1, Kenshi Togashi2, Yongchol Shin1,2, Yasutada Imamura1,2 (1. Appl. Chem. and Chem. Eng. Program, Grad. Sch. of Eng., Kogakuin Univ., 2. Dep. of Chem. and Life Sci., Sch. of Adv. Eng., Kogakuin Univ.)
Comment()

[1P-423]Effect of methyl hesperidin on intercellular adhesion in epithelial cells

○Megumi Kawashima1, Sayori Umada1, Yuzuki Sugiyama2, Yuta Wakao2, Keita Shiratake2, Yasutada Imamura1,2, Yongchol Shin1,2 (1. Appl. Chem. and Chem. Eng. Program, Grad. Sch. of Eng., Kogakuin Univ., 2. Dep. of Chem. and Life Sci., Sch. of Adv. Eng., Kogakuin Univ.)
Comment()

[1P-424]Exploration of Methyl hesperidin Derivatives that Promote Intercellular Adhesion in Epithelial Cells

○Sayori Umada1, Megumi Kawashima1, Yuzuki Sugiyama2, Yuta Wakao2, Eiko Yasui1,2, Imamura Yasutada1,2, Yongchol Shin1,2 (1. Appl. Chem. and Chem. Eng. Program, Grad. Sch. of Eng., Kogakuin Univ., 2. Dep. of Chem. and Life Sci., Sch. of Adv. Eng., Kogakuin Univ.)
Comment()

[1P-425(1AS-16-05)]Identification of Notch3 Ligands Involved in Regulation of Type IV Collagen Expression in Fibroblasts During Angiogenesis

○Yuri Kanomata1, Kazuki Kukita2, Yasutada Imamura1,2, Yongchol Shin1,2 (1. Appl. Chem. and Chem. Eng. Program, Grad. Sch. of Eng., Kogakuin Univ., 2. Dep. of Chem. and Life Sci., Sch. of Adv. Eng., Kogakuin Univ.)
Comment()

[1P-426]Live Imaging of Cell Dynamics in an in vitro Angiogenesis Model Using HUVEC Spheroids

○Kazuki Kukita1, Takahiro Miyamori1, Yasutada Imamura1,2, Yongchol Shin1,2 (1. Dep. of Chem. and Life Sci., Sch. of Adv. Eng., Kogakuin Univ., 2. Appl. Chem. and Chem. Eng. Program, Grad. Sch. of Eng., Kogakuin Univ.)
Comment()

[1P-427]The Role of Long Non-coding RNAs in Radiation-induced Fibrosis

○Mami Yano1,2, Hiroyuki Yano3,1, Ryoji Hamanaka5, Mariko Hida4, Hidekatsu Yoshioka6,1, Noritaka Matsuo1 (1. Oita Univ., 2. Nippon Bunri Univ., 3. Junshin Gakuen Univ., 4. Oita Univ., 5. Oita University of Nursing and Health Sciences., 6. Shinbeppu Hospital)
Comment()

[1P-428]Extracellular proteoglycan lumican suppresses apoptosis of oligodendrocytes and promotes their myelin membrane formation

○Tomoka Aoki1, Reina Ono1, Nobuharu Suzuki1 (1. Department of Clinical Bioanalysis and Molecular Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-429]Functional Analysis of the Syntaxin3 in Epidermal Model Cells, HaCaT

○TAISEI NAKAO1 (1. Kwansei Gakuin University)
Comment()

[1P-430]Morphological abnormalities of cell-cell adhesion in choroid plexus epithelial cells in Daple mutant mice

○Maki Takagishi1, Fuka Oguri1, Hiroki Yoshimoto1, Syu Tokunaga1, Mitsuharu Hattori1 (1. Nagoya City University)
Comment()

[1P-432]The effect of low-voltage pulses on gene transfer by electroporation

○Kahiro Kiuchi1, Hirofumi Kurita1 (1. Toyohashi University of Technology)
Comment()

[1P-433]Optimization of droplet parameters for gene transfection using electrical short-circuiting of a cell suspension droplet

○Shun Tateishi1, Yoshino Tsurusaki1, Rika Numano1, Hirofumi Kurita1 (1. Toyohashi University of Technology)
Comment()

[1P-434]Time-series investigation of cellular mechanisms during gene electrotransfer using a microfluidic device

○Miho Ishii-Teshima1,2, Hirofumi Kurita3, Rika Numano3,4, Takayuki Shibata1 (1. Toyohashi Univ. of Tech., Dept. of mechanical engineering , 2. JSPS Research Fellowship for Young Scientists (RPD), 3. Toyohashi Univ. of Tech., Dept. of Applied Chemistry and Life Science, 4. Toyohashi Univ. of Tech., Institute for Research on Next-generation Semiconductor and Sensing Science)
Comment()

[1P-435]The new application of transformation by the droplet electroporation for cellular engineering

○Rika Numano1,2, Shinozalo Ryuto3, Kurita Hirofumi 2, Shibata Takayuki 4, Matsumoto Kohjiro 5 (1. Institute for Research on next-generation Semiconductor and Sensing Science, Toyohashi University of Technology, 2. Department of Applied Chemistry and Life Science, 3. Okinawa Inst. of Sci. and Tech., Membrane Cooperativity Unit, 4. Toyohashi Univ. of Tech., Dept. of Mech. Engineering, 5. Nepa Gene Co., Ltd.)
Comment()

[1P-436]Dynamin-2 regulates CAMSAP2 localization and microtubule dynamics

○Takenobu Inoue1, Takahiro Chihara1, Misako Okumura1, Kozue Hamao1 (1. Hiroshima University)
Comment()

[1P-437]Visualization and optogenetic manipulation of cholesterol spatiotemporal dynamics to elucidate the physiological significance of dynamic control mechanisms

○Hayate Watanabe1, Yuhei Goto1, Asami Kawasaki2, Shinya Tsukiji3, Fubito Nakatsu2, Kazuhiro Aoki1 (1. Graduate School of Biostudies, Kyoto University, 2. Graduate School of Medical and Dental Sciences, Niigata University, 3. Graduate School of Engineering, Nagoya Institute of Technology)
Comment()

[1P-438]Tppp3 determines basal body positioning and identity of respiratory cilia via microtubule assembly and sphingolipid homeostasis

○Takafumi Sakai1, Katsuyoshi Takaoka2, Sohshiroh Atsumi1, Misaki Kurata1, Hiroshi Tsugawa1, Hiroshi Hamada3, Kyosuke Shinohara1 (1. Tokyo university of aguriculture and technology, 2. Tokushima University , 3. RIKEN Center for Biosystems Dynamics Research)
Comment()

[1P-439]Optical control of actin polymerization on the supported lipid bilayer

○Kei Yamamoto1, Makito Miyazaki1 (1. RIKEN IMS)
Comment()

[1P-440]A Computational Approach to the Mechanism Regulating F-actin Binding by Coronin-1a Phosphorylation

○Risako Matsui1, Honoka Ito1, Xia Anyue1, Teruaki Oku2, Yusuke Ando3, Keisuke Mashima1, Tsuyoshi Sato1 (1. Rikkyo University, 2. Hoshi University, 3. Josai University)
Comment()

[1P-441]Functional role of CD44 in cell competition-mediated elimination of transformed cells

○Yuki Aoshima1 (1. Department of molecular oncology, Graduate school of medicine, Kyoto university)
Comment()

[1P-442]Mechanism of Nuclear Invagination: A Passive Morphological Adaptation for Lamin Stress Relief in Epithelial Cells

○Khoa Minh Le1, Hiroshi Kimura1,2 (1. School of Life Science & Technology - Institute of Science Tokyo, 2. Institute of Integrated Research - Institute of Science Tokyo)
Comment()

[1P-443]Study of nuclear division phenotypes in basidiomycetous yeasts

○Keita Aoki1, Moriya Ohkuma2, Takashi Sugita3, Yuuki Kobayashi1, Naoto Tanaka4, Masako Takashima1 (1. Lab. of Yeast Syst., Tokyo Univ. of Agric., 2. JCM, RIKEN, 3. Dept. of Microbiol., Meiji Pharm. Univ., 4. Dept. of Mol. Microbiol., Tokyo Univ. of Agric.)
Comment()

[1P-444]Effects of Microchamber Geometry on Single-Cell Trapping and Cultivation Performance

○Hidetaka Ueno1, Hajime Shigeto2, Shohei Yamamura2 (1. Kobe Univ., 2. AIST)
Comment()

[1P-445]Novel chemical compounds that are toxic to stationary phase cells

○Minakhi Halder1, Akira Honda2, Yuki Kiyota2, Koichiro Awai1,2, Ayumu Yamamoto1,2 (1. Graduate School of Science and Technology, Shizuoka University, 2. Graduate School of Integrated Science and Technology, Shizuoka University)
Comment()

[1P-446]The mechanisms underlying CDK accumulation at the nucleolus in fission yeast during stationary phase and in response to heat stress

Risa Yoshioka1, Mizuki Terauchi1, Takumi Yamatani1, Shinnosuke Kawai1,2, ○Ayumu Yamamoto1,2,3 (1. Grad. Sch. Integ. Sci. Technol., Shizuoka Univ., 2. Dept. Chem., Faculty Sci., Shizuoka Univ., 3. Grad.Sch. Sci. Technol., Shizuoka Univ.)
Comment()

[1P-447]FRAP analysis underlying the mechanisms of accumulation of CDK at the nucleolus in fission yeast

○Takumi Yamatani1, Mizuki Terauchi1, Risa Yoshioka1, Shinnosuke Kawai1,2, Ayumu Yamamoto1,2,3 (1. Grad.Sch.Integ.Sci.Technol.,Shizuoka Univ., 2. Faculty Sci., Shizuoka Univ., 3. Grad. Sch. Sci. Technol., Shizuoka Univ.)
Comment()

[1P-448]Theanine-induced proliferation suppression in an astrocyte line depends on overexpression of slc38a1.

○Tomoya Tanaka1, Anna Kozima1, Natsuka Watanabe1, Koichi Kawada1, Kyosuke Uno1, Nobuyuki Kuramoto1 (1. setsunan univ.)
Comment()

[1P-449]Mechanism of specific regulation of tumor suppressor genesby the transcription factor E2F in epithelial cells

○Huang WEIWEI1, Kiyoshi Otani1 (1. kwansei Gakuin University)
Comment()

[1P-450(1PS-06-07)]Cancer-Associated USP28 Mutants Disrupt Mitotic Stress Signaling by Impairing 53BP1 Binding and p53 Activation

○MD HAZRAT BELAL1, Esther Fing Ying Ng1, Midori Ohta1, Franz Meitinger1 (1. Okinawa Institute of Science and Technology)
Comment()

[1P-451]Interaction between coral symbiotic bacteria using isolated co-culture vessels and analysis of growth inhibitor

○Shuka Kamiyama1, Rei Nakashima1, Takumi Iida1, Yumi Nishikawa2, Shozo Fukaya3, Natsuko Miura1,2, Mitsuyoshi Ueda4, Michihiko Kataoka1,2 (1. Dept. Appl. Biol. Chem., Grad. Sch. Agric., Osaka Metropolitan Univ., 2. Grad. Sch. Life & Environ. Sci., Osaka Prefecture Univ. , 3. Sanki Seiki Co., Ltd., 4. Grad. Sch. Agriculture, Kyoto Univ.)
Comment()

[1P-452(1AS-10-06)]Unique Division Dynamics of Multinucleated Cells Induced by Cell Fusion

○Joey Nakane1,2,4, Tomomi Tsubouchi2,3,4 (1. Basic Biology, SOKENDAI, 2. Stem cell biology, NIBB, 3. Applied Life Sciences, Agriculture, Shizuoka Univ., 4. Agriculture, Graduate School of Integrated Science and Technology, Shizuoka Univ.)
Comment()

[1P-453]Extracellular environment-driven suppression of mitotic oxidative signaling induces chromosomal instability

○Kenji Iemura1, Kozo Tanaka1 (1. Dept. Mol. Oncol., IDAC, Tohoku Univ.)
Comment()

[1P-454]Mechanistic Insights into Palbociclib-Induced Vitiligo-like Depigmentation: An In Vitro Study

○Min Hua Wu1, Yu Fen Wang1, Hui Ju Yang2,3, Dar Ren Chen1,3,4 (1. Cancer Research Center, Department of Research, Changhua Christian Hospital, Taiwan(R.O.C), 2. Department of Dermatology, Changhua Christian Hospital, Taiwan(R.O.C), 3. Comprehensive Breast Cancer Center, Changhua Christian Hospital, Taiwan(R.O.C), 4. Breast Surgical Oncology Department¸ Changhua Christian Hospital, Taiwan(R.O.C))
Comment()

[1P-455]Analysis of mitotic abnormalities in phospholipid synthesis mutants of fission yeast

○Kosuke Sasaki1, Yasuhiro Matsuo1,2 (1. Graduate School of Natural Science and Technology, Shimane University, 2. Faculty of Life and Environmental Sciences, Shimane University)
Comment()

[1P-456]Control mechanism of chromosome segregation via the glucose response signaling pathway in fission yeast

Moe Yamawaki1, Tomotake Sakai2, Masayuki Yamaga2, ○Yasuhiro Matsuo1,2 (1. Graduate School of Natural Science and Technology, Shimane University, 2. Faculty of Life and Environmental Sciences, Shimane University)
Comment()

[1P-457]The glucose-response signaling pathway regulates amino acid transport in fission yeast

○Ami Kuroki1, Yasuhiro Matsuo1,2 (1. Graduate School of Natural Science and Technology, Shimane University, 2. Faculty of Life and Environmental Sciences, Shimane University)
Comment()

[1P-458]Heat stress influences the spindle assembly checkpoint proteins

○Naoto Kawaguchi1, Youhei Saito1, Ryuzaburo Yuki1, Yuji Nakayama1 (1. Kyoto Pharmaceutical Univ.)
Comment()

[1P-459]Heme biosynthetic pathway functions as a novel inhibitory mechanism controlling cancer cell proliferation and malignancy

○Seiya Watanabe1, Taku Chiabazakura1 (1. Dept. of Bioscience, Tokyo University of Agriculture)
Comment()

[1P-460]PRIM1 contributes to G2/M checkpoint activation and enhances drug-induced DNA damage response in gastric cancer

○Da-Bin Choi1, SeokJun Kim1,2,3 (1. Institute of Well-Aging Medicare & Chosun University G-LAMP Project group, Chosun University, Gwangju, Republic of Korea, 2. Department of Integrative Biological Sciences & BK 21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, Republic of Korea, 3. Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea)
Comment()

[1P-461]KIFC1 function in medaka early embryonic cell division

○Takahiro Yamamoto1, Ai Kiyomitsu1, Yang Ming1, Tomomi Kiyomitsu1 (1. Okinawa Institute of Science and Technology)
Comment()

[1P-462]TXNRD1 phosphorylation rewires ER stress to drive EMT and PD-L1-mediated immune evasion in NSCLC.

○Yaw-dong Lang1, Shin-Yuan Gu2, Tsai-Yu Lin3, Yu-Ching Lee3,4,5, Keng-Chang Tsai1 (1. National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan, 2. Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan, 3. Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan, 4. TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan, 5. Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan)
Comment()

[1P-463]Genetic interaction between Yki and Ctu1 in Drosophila.

○Ryota Kato1, Hideki Yoshida1 (1. Kyoto institute of technology)
Comment()

[1P-464]Regulatory mechanisms of energy metabolism focusing on a short-lived protein

○Kazuki Nonaka1, Kohei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Dept. of Biol. Sci., Grad. Sch. of sci., Nagoya Univ.)
Comment()

[1P-465]Analysis of the rapamycin and insulin-responsive mLST8 interactome by AirID-based proximity biotinylation

○Suzuno Hirano1, Kohdai Yamada1, Hidetaka Kosako2, Tatsuya Sawasaki1 (1. Proteo-Science Center, Ehime University, 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
Comment()

[1P-466]Palmitic Acid-Mediated Autophagy Suppression Through Protein Kinase Pathways in Hepatocytes

Jae Rim Lee1, Myeong Ryeo Kim1, ○Kwang Won Jeong1 (1. College of Pharmacy, Gachon University)
Comment()

[1P-467]Membrane protein synthesis and protein-protein interaction analysis using AirID and wheat cell-free nanodisc method for MARCH family.

○Sara Yoshii1, Kohdai Yamada1, Ryo Morishita2, Hidetaka Kosako3, Tatsuya Sawasaki1 (1. PROS. Ehime Univ., 2. CellFree Sciences Co., Ltd. Research and Development Dept., 3. IAMS. Tokushima Univ.)
Comment()

[1P-468]Branched ubiquitin chain counteracts substrate deubiquitylation

○Miyu Takao1,2, Mai Morita1,2, Fumiaki Ohtake1,2 (1. Institute for Advanced Life Science, Hoshi University, 2. Graduate school of Pharmaceutical Science, Hoshi University)
Comment()

[1P-469]Identification of endogenous factors regulating the targeted protein degradation by PROTAC

○Mai Koizumi1,2, Fumiaki Ohtake1,2 (1. School of Pharmaceutical Sciences, Hoshi University, 2. Institute for Advanced Life Sciences, Hoshi University)
Comment()

[1P-470]The role of p97 cofactors in targeted protein degradation by PROTAC

○Sakura Oya1,2, Fumiaki Ohtake1,2 (1. Hoshi University, 2. Institute for Advanced Life Sciences, Hoshi University)
Comment()

[1P-471]Chemotaxis regulation through GPCR phosphorylation-mediated desensitization

○Yuna Usami1, Yusuke Ono1, Yoichiro Kamimura2, Xuehua Xu3, Tetsuya Muramoto1 (1. Toho University, 2. Nara Medical University, 3. National Institute of Health (NIH))
Comment()

[1P-472]New Insights into Neurotransmission Regulation: "Ca2+-PP2B-PSD95 axis" and Its Regulatory Protein

○Takahiko Chimura1,2, Yuji Kiyama3, Itone Ogawa2, Fumio Nakamura1, Toshiya Manabe2 (1. Tokyo Women's Medical University, 2. The Institute of Medical Science, The University of Tokyo, 3. Kagoshima University)
Comment()

[1P-473]MiniG-Tango as a versatile platform for evaluating GPCR activation via diverse G protein transducers

○So Yamaguchi1,2, Ryoji Kise1, Asuka Inoue1,2 (1. Kyoto University, 2. Tohoku University)
Comment()

[1P-474]Optogenetic Modulation of Cardiac Beating in Human iPS cell-Derived Cardiomyocytes via Photoactivated Adenylyl Cyclase

○Gen Takebe1, Hiromu Sato1, Masumi Takebe1, Shigeru Matsunaga1 (1. Hamamatsu Photonics K.K.)
Comment()

[1P-475]Effects of Aspartate tRNA synthetase dysfunction on the Hippo pathway

○Taito Fukunaga1, Nozomi Watanabe1, Keiichi Ideguchi1, Hideki Yoshida1 (1. Kyoto Institute of Technology)
Comment()

[1P-476]Exosome derived from Goserelin-treated prostate cancer cells promotes inflammation in vascular endothelial cells via NF-κB and IL-1β

○Chih-Pin Chuu1, Yu-Sin Lien1, Sin-Jie Chen1 (1. National Health Research Institutes, Taiwan)
Comment()

[1P-477]Effects of extracellular vesicles (EVs) from lactic acid bacteria on temperature-sensitive TRP channels

○Chika Yamamoto1, Hiroshi Takemori1, Saishi Yoshida2 (1. Gifu Univ., 2. Seki Milk Co.)
Comment()

[1P-478]Long-Range Suppression Mechanism of Notch Signaling mediated by Macrophages

○Yuki Miyata1, Kenji Matsuno2, Tomoko Yamakawa1 (1. Ibaraki Kosen, AC Course, 2. The Univ. of Osaka, Grad. Sch. of Sci., Dept. of Biol. Sci.)
Comment()

[1P-479]Functional analysis of Ulva meridionalis-derived polysaccharide on age-related leaky gut

○Yuka Maejima1, Takushi Namba1,2 (1. Graduate School of Integrated Arts and Sciences, Kochi Univ., 2. Research and Education Faculty, Multidisciplinary Science, Kochi Univ.)
Comment()

[1P-480]Analysis of the selective response mechanism of olfactory receptors to branched alkyl thiols

○Sakura Yoshizumi1, Yosuke Fukutani1 (1. Dept. of Life Sci., Tokyo Univ. Agric and Technol.)
Comment()

[1P-481]Unveiling Potential Natural Compounds from Thai Plants for Anti-Photoaging through An Integrated Cell-Based and Computational Approach

Patcharaporn Saengratwatchara1, Kamonwan Chaikhong1, Panthakarn Rangsinth2, Chanin Sillapachaiyaporn3, George Pak-Heng Leung2, Siriporn Chuchawankul4, Tewin Tencomnao1,5, ○Anchalee Prasansuklab1,6 (1. Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing, Chulalongkorn University, 2. Department of Pharmacology and Pharmacy, The University of Hong Kong, 3. School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, 4. Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, 5. Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, 6. College of Public Health Sciences, Chulalongkorn University)
Comment()

[1P-482]Molecular Mechanism Underlying the Suppression of Garlic Odor by Coffee Aroma

○Amore Tanabe1, Haruka Saito1, Yosuke Fukutani1 (1. Dept. of Life Sci., Tokyo Univ. Agric and Technol.)
Comment()

[1P-483]Long Non-coding RNA plays an important role in the expression of PDGFRαand cell proliferation in the fibroblasts

○Kei Matsuoka1, Ayaka Inami1, Yosei Kato1, Noriko Okuno1, Katsuyoshi Takata1, Seiji Yamamoto1 (1. Department of Pathology, Academic assembly Faculty of Medicine, University of Toyama)
Comment()

[1P-484]Glycation product DHP alters intracellular calcium dynamics and activates the CAMKK2-AMPK-ULK1 pathway

○Shinji Takechi1, Madoka Sawai2, Hisao Kansui1, Yuu Miyauchi1 (1. Fac. Pharmaceut. Sci., Sojo Univ., 2. Sch. Pharm., at Fukuoka. Int. Univ. Health & Welfare)
Comment()

[1P-485]Efficacy of the Dihydropyrazine for Systemic Inflammation

○Madoka Sawai1, Yutaka Tatano1, Katsuya Miyake2, Jian-Rong Zhou3, Hisao Kansui3, Hidetoshi Tozaki-Saitoh1, Yuu Miyauchi3, Shinji Takechi3 (1. Sch. Pharm., at Fukuoka. Int. Univ. Health & Welfare, 2. Cbmr., at Narita. Int. Univ. Health & Welfare, 3. Fac. Pharmaceut. Sci., Sojo Univ)
Comment()

[1P-486]Creation of a human GPCR signal detection system using budding yeast

○Mami Hasegawa1, Egawa Yukiko1, Makoto Ishizaka1, Hiroki Shimamura1, Junko Toshima1,2, jiro Toshima1 (1. Dept. of Bio. Sci. and Tech., Tokyo Univ. of Sci., 2. Sch. of Heal. Sci., Tokyo Univ. of Tech.)
Comment()

[1P-487]Olfactory Receptor-Based Discrimination of Limonene Enantiomers

○Mayuka Ii1, Yosuke Fukutani1 (1. Tokyo University of Agriculture and Technology)
Comment()

[1P-489]IL-11 promotes ICAM-1 expression via the GP130/PI3K/Akt/NF-κB signaling pathway in osteosarcoma metastasis

○Shih-Wei Wang1, Lei-Po Chen3, Hao-Chiun Chang3, Ju-Fang Liu2 (1. MacKay Medical University, 2. Taipei Medical University, 3. MacKay Memorial Hospital)
Comment()

[1P-490]Elucidation of the molecular mechanisms of novel apoptosis induction pathway via tumor suppressor protein PAD7

○Kodai Ueno1,2, Masahiro Takikawa1, Jayaraman Krishnaraj1, Yuko Tabata1, Yuzo Watanabe3, Atsushi Okabe4,5, Ryoji Fujiki4, Ami Mochizuki1, Airi Nakano1,2, Shigetaka Nishiguchi6, Rinshi S. Kasai7, Atsushi Kaneda4,5, Fuyuki Ishikawa8, Rieko Ohki1 (1. Laboratory of Fundamental Oncology, National Cancer Center Research Institute, 2. Graduate School of Biomedical Sciences, Nagasaki University, 3. Proteomics Facility, Graduate School of Biostudies, Kyoto University, 4. Department of Molecular Oncology, Graduate School of Medicine, Chiba University, 5. Health and Disease Omics Center, Chiba University, 6. National Institute of Advanced Industrial Science and Technology, 7. Division of Advanced Bioimaging, National Cancer Center Research Institute, 8. Department of Gene Mechanisms, Graduate School of Biostudies, Kyoto University)
Comment()

[1P-491]regulation of hepatocarcinogenesis and intrahepatic cholangiocarcinogenesis via fucosylation control mediated by the p53 target gene p53PAD1

○EREN TSUDA1,2, Naoya Kobayashi2,3, Musashi Kagaya4,2, Die Hu2, Tomoko Tajima2, Yukiko Sakaguchi2, Yuko Tabata2, Kiyono Aoki2, Daisuke Shiokawa5, Masahiro Yamamoto6, Minoru Narita1,7, Rieko Ohki2 (1. Hoshi Univ., 2. National Cancer Center , 3. Science Tokyo Univ., 4. Kitasato Univ., 5. Ehime Univ., 6. Kumamoto Univ., 7. National Cancer Center)
Comment()

[1P-492]Hippo pathway controls biopterin metabolism to shield adjacent cells from ferroptosis in lung cancer

○Hao Li1,2, Yohei Kanamori2, Akihiro Nita3, Toshiro Moroishi3 (1. Kwansei Gakuin University, 2. Kumamoto University, 3. Institute of Science Tokyo)
Comment()

[1P-493]Investigation of Nucleolar Stress in Replicative Senescent Cells with a Focus on Nucleolar Proteins

○Satsuki Kimura1, Akiho Kawaguchi1, Yuki Nishino1, Taro Tachibana1, Chikako Yokoyama1 (1. Osaka Metropolitan Univ.)
Comment()

[1P-494(1AS-14-03)]An Innate Immune Receptor Toll-1 Converts Chronic Light Stress into Glial-Mediated Neurodegeneration

○Jiro Osaka1, Toshiharu Ichinose2,3, Mai Kanno2,3, Satoko Hakeda-Suzuki4,1, Takashi Suzuki1, Atsushi Sugie5 (1. Graduate School of Life Science and Technology, Institute of Science Tokyo, 2. Frontier Research Institute for Interdisciplinary Science, Tohoku University, 3. Graduate School of Life Science, Tohoku University, 4. Research Initiatives and Promotion Organization, Yokohama National University, 5. KYOTO Drosophila Stock Center, Kyoto Institute of Technology)
Comment()

[1P-495]Involvement of autophagy in starvation-responsive cell death in insect ovaries

○Kaede Endo1, Taiki Sunada1, Ryoka Kakimoto1, Eiji Kotani1, Keiko Takaki1 (1. Kyoto Institute of Technology)
Comment()

[1P-496]Heavy water toxicity via kinetic isotope effects: Stronger than high-dose radiation, Neutralized by light water

○Takeshi Yasuda1, Nakako Izumi Nakajima2, Tomoko Yanaka1, Takaya Gotoh3, Katsushi Tajima4 (1. iQLS, QST, 2. QST hospital, QST, 3. Department of Health Science, Daito Bunka Univ., 4. Department of Hematology, Yamagata Prefectural Central Hospital)
Comment()

[1P-497]Banaba Leaf Extract and Corosolic Acid mitigates palmitic acid-induced insulin resistance in HepG2 Cells

○JeongHyeon Shim3, ChangMIn Lee3, JinYoung Kim3, KilHwan Kim4, GwangWon Cho2,1,3 (1. Department of Biological Science,College of Natural Sciences, Chosun University, Korea, 2. The Basic Science Institute of Chosun University, Chosun University, Gwangju 61452, Korea, 3. Department of Integrative Biological Science, BK21 FOUR Education Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, Korea, 4. Veterans Health Service Medical Center, Veterans Medical Research Institute, Seoul 05368, Korea)
Comment()

[1P-498]Exploring the effects of Corosolic acid, a major component of banaba leaf extract, on Type 2 Diabetes and Sarcopenia

○Jin-Young Kim3, Chang-Min Lee3, Jeong-Hyun Shim3, Kil Hwan Kim4, Gwang-Won Cho1,2,3 (1. Department of Biological Science, College of Natural Sciences, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 501-759, Korea., 2. The Basic Science Institute of Chosun University, Chosun University, Gwangju 61452, Korea. , 3. Department of Integrative Biological Science, BK21 FOUR Education Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju 61452, Korea., 4. Veterans Health Service Medical Center, Veterans Medical Research Institute, Seoul 05368, Korea)
Comment()

[1P-499]Changes in collagen expression and induction of endoplasmic reticulum stress during senescence in granulosa cells.

○Yuki Morioka1, Takushi Namba1,2 (1. Graduate School of Integrated Arts and Sciences, Kochi Univ., 2. Research and Education Faculty, Multidisciplinary Science, Kochi Univ.)
Comment()

[1P-500]Hybrid Synthesis of Curcumin-Based Fluorescent Probes

○Miki Kikuchi1, Nozomi Shiono1, Ryuuhei Takeshita1, Takuma Shiraki1 (1. Kindai University)
Comment()

[1P-501]Cannabidiol (CBD) Products Induce Cell Death in an Ex Vivo Precision Cut Lung Slice Model

○Nadia Milad1,2, Yoko Miura1, Min-Seok Kim3, Satoshi Kanazawa1 (1. Nagoya City University, 2. McMaster University, 3. Korea Institute of Toxicology)
Comment()

[1P-502]Screening for novel Glyoxalase I inhibitors and evaluation of their inhibitory activity and cell death inducibility

○Shuji Ishizaki1,2, Atsushi Yoshimori2, Ryoko Takasawa1 (1. Facul. Pham. Sci., Tokyo Univ, 2. ITM, Inc)
Comment()

[1P-503]Study on Non-Invasive Microplasma-based Regulation of the Yeast Cell Cycle

○Soichiro Kinoshita1, Farhana Begum2, Md Jahangir Alam2, Mahedi Hasan3, Abubakar Hamza Sadiq3, Jaroslav Kristof3, Kazuo Shimizu1,2,3 (1. Shizuoka University Graduate School of Integrated Science and Technology, 2. Shizuoka University Graduate School of Medical Photonics, 3. Shizuoka University Graduate School of Science and Technology)
Comment()

[1P-504]Cellular senescence inhibits infection with influenza A virus

○Mayu Ito1, Hiroshi Kimura2, Yasuyuki Miyake2,3 (1. Nagoya University School of Medicine, 2. Department of Virology, Graduate School of Medicine, Nagoya University, 3. Nagoya University Institute for Advanced Study)
Comment()

[1P-505]Asymmetric segregation of ribosomal RNA genes and the effect of taurine on their stability in budding yeast.

○NANASE ONO1, Masahiko Harata1, Chihiro Horigome1 (1. Tohoku University)
Comment()

[1P-506]Mechanistic analysis of selective cytotoxicity induced by plasma-activated Ringer’s lactate solution in breast cancer cells

○Ayako Tanaka1, Masaaki Mizuno2, Shinya Toyokuni1,3, Hiroaki Kajiyama1,4, Masaru Hori1, Hiromasa Tanaka1 (1. Center for Low-temperature Plasma Sciences, Nagoya University, 2. Internal Center for Research, Education, and Development for Healthcare Life Design (iC-REX), Graduate School of Medicine, Nagoya University, 3. Department of Pathology and Biological Responses, Graduate School of Medicine, Nagoya University, 4. Department of Obstetrics and Gynecology Nagoya, Graduate School of Medicine, Nagoya University)
Comment()

[1P-508(1PS-03-07)]The mechanism of cellular senescence induction by lysosomal membrane damage

○Taiichi Osumi1,2, Takayuki Shima1,2, Makoto Horikawa1,2, Shuhei Nakamura1,2 (1. Department of Biochemistry, Nara Medical University, 2. Center for Autophagy and Anti-Aging Research, Nara Medical University)
Comment()

[1P-509]The effects of heterodimeric partner DP1 on the activity of the transcription factor E2F1 deregulated from the tumor suppressor pRB

○Saki Miyata1, Kiyoshi Ohtani1 (1. Department of Biomedical Chemistry, Graduate School of Science and Technology, Kwansei Gakuin University)
Comment()

[1P-511]Crosstalk between the RB-E2F pathway and Hippo pathway

○Sakurako Isa1, Kiyoshi Ohtani1 (1. Department of Biomedical Chemistry, Graduate School of Science and Technology, Kwansei Gakuin University)
Comment()

[1P-512]Suppression of ferroptosis in activated macrophage-like cells

○Ayaki Shirai1, Kato Shigetada1, Kusumi Ryousuke1, Kakihara Nahoko1, Sato Hideyo1 (1. Niigata University)
Comment()

[1P-514]Novel regulatory mechanisms of the MDM2-p53 pathway via crosstalk between acetylation and ubiquitination

○Ryuto Komatsu1, Yusuke Hirata1, Takuya Noguchi1,2, Atsushi Matsuzawa1 (1. Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ., 2. Dep. of Medical Biochem., Sch. of Pharm., Iwate Med. Univ.)
Comment()

[1P-515]Live cell imaging analysis of apoptotic processes of human retinal pigment epithelium cells (ARPE-19) induced by a 450nm blue-light irradiation

○Kenji Sugimoto1,2, Ai Yamaguchi2, Mana Kitao1, Ryo Hayakawa1, Kaori Murata2, Tatsuya Takahashi2,3, Mitsugu Akagawa4 (1. Osaka Prefecture Univ., Life & Environ. Sci., 2. Cellular Damage Evaluation of Ionizing Radiation and Blue Light, 3. Takahashi LCC, 4. Tokushima Univ.)
Comment()

[1P-516]Analysis of the mechanism of cell death induction in dormant cancer cells by drugs that impair mitochondrial function

○Kotaro Miyamoto1, Shinae Kondoh1,2, Tetsuya Kadonosono1 (1. Institute of Science Tokyo, 2. National Institute of Technology, Nara College)
Comment()

[1P-517]‘‘The mechanisms of the attenuated phagocytosis of apoptotic cells by macrophages in aged mice‘‘

○Daisuke Yamaguchi1, Yoshitaka Kondou2, Akihito Ishigami2, Kisaburou Nagata1 (1. Toho University , 2. Tokyo Metropolitan Institute for Geriatrics and Gerontology)
Comment()

[1P-520]Suppression of ferroptosis in hepatic cells by FBPSD and its underlying mechanism

○Eri Aoki1, Yuko Futagami2, Toshiki Hyodo3, Kenzo Sakaguchi4, Hirofumi Kawazi5, Kazuhiro Shiozaki1,2,3 (1. Food Innovation Sci., Grad. Sch. Agricult. Forest. Fish., Kagoshima Univ. , 2. Kagoshima Univ. , 3. Unit. Grad. Sch. Agricult. Sci., Kagoshima Univ., 4. Eidensha, 5. Eiden engineering)
Comment()

[1P-521]Senolytic Activity of Shea Butter-Derived Amyrins

Mikako Hirose1, Shimpei Watanabe3, Yasunori Fujita2, Satoshi Ohta3, ○Masataka Sugimoto1 (1. National Center for Geriatrics and Gerontology, 2. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 3. Fuji Oil Co., Ltd)
Comment()

[1P-522]Clec4a2 deficiency promotes osteoclast cell death and suppresses acute inflammation-induced bone loss

○Hirofumi Fujita1, Yuma Tai1, Kenji Takahashi1, Yuto Ueda1, Wakana Kitagawa3, Mitsuaki Ono2,3, Toshitaka Oohashi2, Hideyo Ohuchi1 (1. Dept. Cyto. & Histo., Okayama univ., 2. Dept. Mol. Biol. & Biochem., Okayama univ., 3. Dept. Oral Reha. & Regene., Okayama univ.)
Comment()

[1P-523]The Role of the MAP Kinase Pathway in Ferroptosis Induction

○Kota Fukui1, Masaru Murakami2, Masayuki Funaba1 (1. Graduate School of Agriculture, Kyoto University, 2. Azabu University School of Veterinary Medicine)
Comment()

[1P-524]A new standard for enzyme-free cell harvesting - temperature-responsive cell cultureware UpCell®

○Asumi Yoshihara1, Eriko Ikeda1, Yuzo Kasuya1 (1. CellSeed Inc.)
Comment()

[1P-525]Metabolic Engineering of Methylobacterium extorquens for Methanol-Based Lactic Acid Production

○Hsin-Yi Lee1, Li-Xiang Lin1, Chang-Ting Tsai1, Yu-Cheng Chang1, Shih-Hung Hsieh1, Jui-Hui Chen1, Ethan I Lan2, You-An Chen2, Billy C. Hung2, Yu-Chieh Li2, Hsiao-Ping Lee1 (1. Refining & Manufacturing Research Institute, CPC Corporation, Taiwan, 2. Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Taiwan)
Comment()

[1P-526]Development of DNA immunization antibody creation methods using exosome proteins and generation of rat monoclonal antibodies against medaka CD4

○Yosuke Yoshida1, Yuzi Ito1, Norimasa Iwanami2, Yukiko Ogino3, Chikako Yokoyama1, Taro Tachibana1 (1. Osaka Metropolitan Univ., 2. Utsunomiya Univ., 3. Kyushu Univ.)
Comment()

[1P-527]Let’s explore a new epistemology through the philosophy of biology

○Kosuke Sato1 (1. Hokkaido University, Graduate School of Science)
Comment()

[1P-528]Dynamic network visualization tool for biological system

○Kentaro Inoue1 (1. Miyazaki Univ.)
Comment()

[1P-529(1AS-18-03)]Photo-dependent cytosolic delivery of biofunctionalized microparticles in living cells

○Shouhei Kobayashi1, Takako Koujin1, Noriko Fukuta1, Kayoko Ujiie1, Chie Mori1 (1. NICT)
Comment()

[1P-530]Mechanisms of lipid accumulation in oleaginous yeast Lipomyces starkeyi : From analysis to application

○Yuko Takayama1, Takae Hirasawa1, Emi Kuriyagawa1, Michiko Suma2, Shigeaki Saitoh2 (1. Teikyo University, 2. Kurume University)
Comment()

[1P-531]Transcriptional, Epigenomic, and Metabolomic Changes Induced by Short-Chain Fatty Acids in Intestinal Epithelial Cells

○Miho Seki1, Karen Minowa1, Yuina Inokuma2, Kanata Naito2, Teruya Kaneko1, Syota Ichinose1, Satoshi Yamashita1,2 (1. Maebashi Institute of Technology, Graduate School of Engineering, Department of Biotechnology, 2. Maebashi Institute of Technology, Faculty of Engineering, Department of Biotechnology)
Comment()

[1P-532]Phenotypic Changes in Pluripotent Stem Cells during Long-Term Passaging

○Shuuji Mawaribuchi1, Maiko Iida1 (1. National Institute of Advanced Industrial Science and Technology (AIST))
Comment()

[1P-533]Isojacareubin Inhibits Proliferation and Migration in Chemoresistant Triple-Negative Breast Cancer

○Yi En Liu1, Wan Ting Shen2, Han Tsang Wu1, Dar Ren Chen1,3 (1. Cancer Research Center, Department of Research, Changhua Christian Hospital, Changhua 500, Taiwan, 2. Laboratory of Molecular and Surgical Research, Department of Research, Changhua Christian Hospital, Changhua 500, Taiwan, 3. Comprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua 500, Taiwan)
Comment()

[1P-534]Metformin Enhances the Cytotoxicity of Palbociclib in a Palbociclib-Resistant T47D Breast Cancer Cell Line

○Wan-Ting Shen1, Yi-En Liu2, Wei-Chung Shia1 (1. Laboratory of Molecular and Surgical Research, Department of Research, Changhua Christian Hospital, 2. Cancer Research Center, Changhua Christian Hospital)
Comment()

[1P-535]Functional analysis of the DCAF family protein COP1 for development of protein degrader

○Kenshi Tanaka1,2, Kohei Nishino3, Hidetaka Kosako3, Tatsuya Sawasaki1, Satoshi Yamanaka1,2 (1. Division of Cell-Free Life Sciences, Proteo-Science Center, Ehime University, 2. Division of Proteo-interactome, Proteo-Science Center, Ehime University, 3. Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University)
Comment()

[1P-536(1PS-05-01)]Expansion STED Microscopy for the Imaging of Synaptic and Organelle Proteins

○Ehoto Osogaguchi1,2, Hiroshi Kawabe1 (1. Department of Pharmacology, Graduate School of Medicine, Gunma University, 2. School of Medicine, Faculty of Medicine, Gunma University)
Comment()

[1P-537]Genetic analysis by RMCE in Anhydrobiotic Pv11 cells.

○Masahiko Hotta1,2, Yuki Yoshida2, Takahiro Kikawada1,2 (1. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo., 2. Biological Function Research Group, Division of Biomaterial Sciences, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization.)
Comment()

[1P-538]Engineering cells via serine recombinases-based permanent genetic memory circuits

○Miyu Otsuka1, Tomohiro Nawata2, Toshiki Saito2, Koko Nakata2, Shunsuke Takahashi1 (1. Div. Life Sci. Eng., Sch. Sci. Eng., Tokyo Denki Univ., 2. Dept. Life Sci. Eng., Grad. Sch. Sci. Eng., Tokyo Denki Univ.)
Comment()

[1P-539]Influence of positively charged nanobubbles to neurons

○Yifan Liu1, Takeshi Ohdaira2, Emi Kitakata2, Yoshihisa Harada2, Kumiko Hayashi2 (1. The University of Tokyo, 2. The Institute for Solid State Physics ,The University of Tokyo)
Comment()

[1P-540]Mechanism of uptake of extracellular vesicles contained in edible plants by gastrointestinal cancer cell lines

○Mei Ishikawa1, Akari Saito2, Hiyori Funayama2, Kana Matsumoto1,3, Satoru Monzen3,4, Mitsuru Chiba1,3 (1. Dep. Biosci. Lab. Med. Hirosaki Univ., 2. Dep. Med. Tech. Hirosaki Univ., 3. Research Center Biomed. Sci. Hirosaki Univ., 4. Dep. Radiat. Sci. Hirosaki Univ.)
Comment()

[1P-541]Artificial Modification of the Phycobilisome in the Unicellular Red Alga Cyanidioschyzon merolae

○AMI KATSUMATA1 (1. Tokyo University of Agriculture)
Comment()

[1P-542]Functional analysis of apple pomace extract on human skin fibroblasts

○Naoki Nanashima1, Hayato Maeda2, Akira Nakajima2, Makoto Nishizuka2, Tsuyoshi Narumi3, ichita Junji3,4, Kho Itoku3 (1. Aomori Univ. of Health and Welfare, 2. Hirosaki Univ., 3. Nihon Haruma, 4. Shibata Gakuen Univ.)
Comment()

[1P-543]Single-cell imaging of Escherichia coli lysis caused by phage infection using a tabletop scanning electron microscope

○Fumiaki Hamazato1, Takafumi Miwa1, Akiko Hisada1 (1. Research and Development Group, Hitachi, Ltd.)
Comment()

[1P-544]Investigation of physiological phenomena underlying cell polarization properties toward application in cell sorting

○Kagefumi Todo1, Masayo Takano2, Yoshikazu Wakizaka2, Kyoichi Oshiro2 (1. Tokiwa Univ., 2. AFI Corporation)
Comment()

[1P-545]A Robust Protocol for Proteomic Profiling of Secreted Proteins in Conditioned Culture Medium

○Takayoshi Otsuka1, Atsushi Hatano2, Masaki Matsumoto2, Hideaki Matsui1 (1. Brain Research Institute, Niigata University, 2. Dept. of Omics and Systems Biology, Niigata University)
Comment()

[1P-546]Effects of Low-Molecular-Weight Fucoidan Extract on Tumor-Associated Macrophages

○Yusuke Ota1, Hiroshi Eto2, Kiichiro Teruya3 (1. Grad. Sch. Biores. Bioenv. Sci. Kyushu Univ., 2. Daiichi Sangyo Co. Ltd., 3. Fac. Agr. Kyushu Univ)
Comment()

[1P-547]Exhaustive investigation of genes for intracellular pH regulation in B.subtilis

○Takeru Kurakawa1,3, Hiroko Fukuda1,3, Atsuya Uchigaki1,3, Mikio Nakajima3,4, Hirotada Mori2,3, Masahiro Mizuno1,3, Masakazu Kataoka2,3 (1. Grad. Sch. Sci. Technol., Shinshu Univ., 2. Eng. Fac. Eng., Shinshu Univ., 3. RCAM., Shinshu Univ, 4. Freelance)
Comment()

[1P-548]Sex difference of cell competition via UTX in mouse pancreas

○Yuta Sakae1, HeeWon Seo1, Shunsuke Kon1 (1. Res. Inst. for Biomed. Sci.,Tokyo Univ. of Sci)
Comment()

[1P-549]Investigation of electroporation conditions enabling high-efficiency transfection into THP-1 cells

○Nao Tsuchida1, Hayata Ano1, Rina Shibata1, Tadayoshi Karasawa2, Masafumi Takahashi2, Fumitake Kawanishi1 (1. Toyama Prefectural Univ., 2. Jichi Medical Univ.)
Comment()

[1P-550]Development of the screening system for hazardous nanoplastic particles using fluorescent protein-based indicators

○Kazuki Harada1, Yudai Ikuno1, Kosuke Tanaka2, Osamu Udagawa1, Tomohiro Ito1, Fumihiko Maekawa1, Tetsuya Kitaguchi3, Takashi Tsuboi4 (1. Health and Environmental Risk Division, National Institute for Environmental Studies, 2. Material Cycles Division, National Institute for Environmental Studies, 3. Institute of Integrated Research, Institute of Science Tokyo, 4. Graduate School of Arts and Sciences, The University of Tokyo)
Comment()

[1P-551]Novel approach to analyze gene functions by using conditional-rescue transgenic mice technique.

Eiki Sakurai1, Takaaki Fushimi1, ○Daisuke Watanabe1 (1. Kitasato Univ. dept. Sci)
Comment()

[1P-552(1PS-10-08)]UNC-43/CaMKII regulates presynaptic assembly in C.elegans

○Kota Mizumoto1, Mizuki Kurashina1 (1. University of British Columbia)
Comment()

[1P-553]The N143T mutation in mouse fibroblast growth factor 9 causes vertebral fusion along the rostrocaudal axis

○Masayo Harada1, Georgena Djameh1, Keiichi Akita1 (1. Institute of Science Tokyo)
Comment()

[1P-554]Effects of BMP/Smad signaling deficiency on the differentiation of intestinal absorptive epithelial cells and tumorigenesis induced by loss of Apc gene

○Karin Kinoshita1, Moena Fukuda1, Akiko Tomiyama1, Rika Tatsukawa1, Yoshimi Uchida1, An Zwijsen2, Etsu Tashiro1, Naoko Nakano1, Fumiko Itoh3, Susumu Itoh1 (1. Laboratory of Biochemistry, Showa Pharmaceutical University ,, 2. KU, Leuven, Belgium, 3. Laboratory of Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama)
Comment()

[1P-555]Shared and Unique Features of Limb and Skin Regeneration in Xenopus laevis Revealed by Transcriptome Analysis

○Rina Sato1, Takuya Kobayashi2, Ayumi Konishi1, Ikuo Uchiyama3, Kentaro Abo1, Hiroyo Nishide3, Hiroki Sugiura3, Mikiko Kotani1, Katsushi Yamaguchi3, Shuji Shigenobu3, Koji Tamura2, Hitoshi Yokoyama1 (1. Hirosaki University, 2. Tohoku University, 3. National Institute for Basic Biology)
Comment()

[1P-556]Mechanisms of epithelial–stromal interactions mediated by estrogen receptor in the mouse vagina

○Moeka Sakaguchi1, Eriko Senoo1, Tatsuki Goto1, Sho Ymazaki1, Ayaka Sasaki2, Kenji Toyota1,3, Shinichi Miyagawa1,2 (1. Department of Biological Science and Technology, Graduate School of Advanced Engineering, Tokyo University of Science., 2. Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science., 3. Graduate School of Integrated Sciences for Life, Hiroshima University.)
Comment()

[1P-557]Development of skin regeneration technology using intercellular linkage gel based on mechanobiology

○Ayane Kunieda1, Natsumi Ueda1, Koji Nagahama2 (1. graduate school Konan Univ., 2. Konan Univ.)
Comment()

[1P-558]Analysis of mesenchymal stromal cell distribution during medaka embryogenesis

○Ayano Kobayashi1, Takafumi Ikeda2, Kiyoshi Naruse3, Hiroyuki Takeda2, Rie Kusakabe1 (1. Graduate School of Kansai University, 2. Kyoto Sangyo Univ., 3. NIBB)
Comment()

[1P-559]Development of Fully Xenogeneic blood in Runx1 cKO mice without irradiation via Intraplacental Transplantation

○CHINGWEI LIAO1,2, Hyojung JEON3, Arata Wakimoto4, Zeynab Javanfekr Shahri1,2, Natalia Gogoleva1,2, Michito Hamada1, Satoru Takahashi1 (1. Department of Anatomy and Embryology, University of Tsukuba, 2. Ph.D. program in Human Biology, 3. Division of Cell Regulation, The institute of medical science, The university of Tokyo, 4. University of Washington)
Comment()

[1P-560]Elucidation of the molecular and developmental mechanism by which birds evolutionarily acquired flight feather

○Momoko kyushin1, Keiji Kinoshita2, Takayuki Suzuki1 (1. Osaka Metro. Univ., 2. Yunnan Agricultural Univ.)
Comment()

[1P-561]Heterotypy in the C-terminal domain of Gli3 reveals species-specific developmental constraints in mammals

○Sota Ikeda1, Hiromi Matsumae2, Satoshi D Ohdachi3, Sayaka Tojima1, Tadashi Nomura1,4 (1. Applied Biology, Kyoto Institute of Technology, 2. Department of Molecular Life Sciences, School of Medicine, Tokai University, 3. Institute of Low Temperature Science, Hokkaido University, 4. Center for Social and Biomedical Engineering, Kyoto Institute of Technology)
Comment()

[1P-562]Role of type IX collagen in the morphogenesis of fin skeleton in zebrafish

○Jin Hagiwara1,2, Hibiki Nakagawa1, Shigeru Kondo1, Junpei Kuroda1,2 (1. Grad. School of FBS, The University of Osaka, 2. JT Biohitory Reseach Hall)
Comment()

[1P-563]Disruption of the Shh Limb-Specific Enhancer Using Genome Editing Causes Limb Truncation in the Gecko

○Takaya Abe1, Mari Kaneko1, Hiroshi Kiyonari1 (1. RIKEN BDR)
Comment()

[1P-564]Elucidation of Epithelial Morphogenetic Logic Using the Drosophila Wing Imaginal Disc as a Model

○Hiroshi Hosoi1, Chigusa Hinata1, Yasuhiro Inoue2, Masakazu Akiyama3, Shizue Ohsawa1 (1. Group of Genetics, Division of Biological Science, Graduate School of Science, Nagoya University, 2. Department of Micro Engineering, Graduate School of Engineering, Kyoto University, 3. Department of Mathematics, Faculty of Science, Academic Assembly, University of Toyama)
Comment()

[1P-566]Regulation of Wnt signaling by heparan sulfate modifications of Syndecan4

○Tatsunobu Kakuzen1, Minako Suzuki1, Mototsugu Eiraku1, Yusuke Mii1 (1. Institute for Life and Medical Sciences, Kyoto University)
Comment()

[1P-567]Dissecting the mechanistic link between cell chirality and chiral actin fiber formed by class I myosins

○Daiki Kitamura1, Haruna Nishikawa1, Mikiko Inaki2, Takamichi Sushida3, Kenji Matsuno1 (1. Department of Biological Sciences, Graduate School of Science, The University of Osaka, 2. Department of Life Science, Graduate School of Science, University of Hyogo, 3. Faculty of Informatics, The University of Fukuchiyama)
Comment()

[1P-568(1AS-03-02)]Is the Dpp/BMP morphogen scaling required for scaling of wing vein patterns in the Drosophila wing?

○Shinya Matsuda1, Kaoru Sugimura1 (1. University of Tokyo)
Comment()

[1P-569(1PS-14-03)]The Notch–TGFβ2 axis mediates endothelial–pericyte interaction to promote angiogenesis via enhancing type 4 collagen vascular basement membrane formation.

○semanti Halder1, Honami Ogo1, Yasuyuki Hanada1, Vishnuvardhinidutt Kasi1, Yuka Ozeki1, Katarzyna Anna Inoue2, Miho Kobayashi2, Tetsuro Watabe2, Akiyoshi Uemura3, Koichi Nishiyama1 (1. Lab. for Vasc. and Cell. Dyn., Fac. of Medicine, Univ. of Miyazaki, 2. Dept. of Biochem., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ. , 3. Dept. of Retinal Vasc. Biol., Nagoya City Univ. Grad. Sch. of Med. Sci.)
Comment()

[1P-570(1AS-08-07)]Understanding the molecular mechanisms controlling body color of ornamental teleost fish strains (Oryzias latipes and Cyprinus carpio)

○Yoshihiro Omori1,2, Tetsuo Kon3, Rui Tang2, Koto Kon-Nanjo3, Soichiro Fushiki2, Soma Tomihara1,2, Yusuke Takehana2, Atsushi Toyoda 4, Hideki Noguchi4,5, Kohji Mabuchi6, Kiyoshi Naruse7 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. Graduate School of Bioscience, Nagahama Institute of Bioscience and Technology, 3. Department of Neurosciences and Developmental Biology, University of Vienna, 4. National Institute of Genetics, 5. Center for Genome Informatics, ROIS-DS, 6. National Institute for Environmental Studies, 7. National Institute for Basic Biology)
Comment()

[1P-571]Molecular mechanisms of JunB-mediated vascular network formation via neuro-vascular interactions.

○Yasuo Yoshitomi1, Hidehito Takatsuji, Takayuki Ikeda, Hideto Yonekura (1. Kanazawa Med. Univ. Sch. Med.)
Comment()

[1P-572(1MS-04-05)]Analysis of cell dynamics regulated by a novel bleb-like structure dependent on planar cell polarity

○Minako Suzuki1, Shinji Takada2, Yusuke Mii1 (1. Kyoto Univ., 2. NIBB)
Comment()

[1P-573]Induction of Sweat Glands in Mouse ES Cell-Derived Skin Organoids

○Rina Takagi1, Mototsugu Eiraku1,2 (1. Graduate School of Engineering, Kyoto University, 2. Department of Developmental Systems Control, Institute for Medical Biology, Kyoto UniversityLaboratory of Developmental Systems, Institute for Life and Medical Sciences, Kyoto University)
Comment()

[1P-574]Manipulation of signal dynamics to investigate oscillatory shuttling of transcription factors

○Kensuke Yamashita1, Tetsuya Muramoto1 (1. Toho University)
Comment()

[1P-575]Development of a Microplatform for Single-Cell Assembly and Cultivation

○Jotaro Omura1, Takumi Ito1, Hidekuni Takao1, Kyohei Terao1 (1. Kagawa University)
Comment()

[1P-576]Isoform specific functions of the Insulin receptor in red flour beetle, Tribolium castaneum

○Hina Akamatsu1, Nono Daidouji1, Eiji Kotani1, Keiko Takaki1 (1. Kyoto Institute of Technology)
Comment()

[1P-577]Keratinocytes defy topography to autonomously form a smooth cell sheet on a bumpy micropatterned substrate

Nozomu Kitamura1, Kennedy Omondy Okeyo2, Masahiro Sokabe3, ○Hiroaki Hirata1 (1. Dept. Life Sci. Biotech., Kanazawa Inst. Tech., 2. Weldon Sch. Biomed. Eng., Purdue Univ., 3. Human Info. Sys. Lab., Kanazawa Inst. Tech.)
Comment()

[1P-578]Skin vascularization induced by conditional VEGFA-secreting fibroblasts

○Lin Gao1, Yoshihiko Kobayashi1, Riki Ishibashi2, Shiya Abe1, Fumiko Toyoshima1 (1. Institute of Science Tokyo, 2. Kyoto University)
Comment()

[1P-580]What triggers dedifferentiation and proliferation of glial cells at the onset of Drosophila metamorphosis

○Kentaro Kato1, Eriko Nozaki2, Takeshi Awasaki1 (1. Dept Biol, Sch Med, Kyorin Univ, 2. Core Lab Pro Gen , Sch Med, Kyorin Univ)
Comment()

[1P-581]Mechanism of Motor Function Enhancement by the Tendon- and Ligament-Specific Transcription Factor Mkx

○Kasumi Yumoto1, Takahide Matsushima1, Tomoki Chiba1, Maiko Inotsume1, Takahiro Morita1, Hiroshi Asahara1 (1. Institute of Science Tokyo)
Comment()

[1P-582]Identification of the skin care function of biomimetic vernix caseosa composition using a reconstructed human epidermis model

○Tong Xie1, Wu Qiao1, Tinghan Jia1, Kaku Ken1 (1. Pigeon Manufacturing (Shanghai) Co., Ltd.)
Comment()

[1P-583]Tetraploid complementation partially rescues the Fgfr2b knockout mouse phenotype.

○Ayako Isotani1, Yamato Murata1, Shunsuke Yuri1,2 (1. Nara Institute of Science and Technology, 2. National Center for Geriatrics and Gerontology)
Comment()

[1P-584]Evolution of gch genes in teleost lineage and their functions in pigment cell differentiation

○Rin Hara1, Souta Kino1, Hayato Yokoi1 (1. Tohoku university)
Comment()

[1P-585]Dachsous/Fat signaling molecules are involved in the positional information of the hindlegs during intercalary regeneration in the cricket

○Tetsuya Bando1, Hana AO2, Riko Michishita2, Hideyo Ohuchi1 (1. Okayama Univ Grad Sch. Med. Dent. Pharma, Dept. Cyto. Hist., 2. Okayama Univ. Med. Sch., Fact. Med.)
Comment()

[1P-586]Role of Hofbauer cells in vascular development and structural organization of the mouse placenta

○ZIWEI YIN1, Yuki Hattori1 (1. Graduate School of Medicine, Nagoya University)
Comment()

[1P-587]Piwi regulates tissue size via endocycling in Drosophila melanogaster

○Tetsuo Yasugi1, Yuma Hashimoto1, Jie Yu2, Keisuke Shoji2 (1. Sophia Univ., 2. TUAT)
Comment()

[1P-588]Transdifferentiation of cell by ribosomal protein

Anamika Datta1, Arif Istiaq1, Keisuke Yamashita1,2, ○Kunimasa Ohta1,2 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Faculty of Art & Sciences, Kyushu University)
Comment()

[1P-589]Transdifferentiation of Chick Primary Muscle-Derived Cells Induced by Lactic Acid Bacteria-Derived Ribosomes

○Shota Inoue1, Kunimasa Ohta1,2, Ikko Kawashima3 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Faculty of Arts and Science, Kyushu University, 3. IntegriCulture)
Comment()

[1P-590]DNA microarray data analysis to distinguish adipose-derived or bone marrow-derived mesenchymal stroma/stem cells from fibroblasts

○Masami Kanawa1, Katsumi Fujimoto2, Tania Saskianti 3, Ayumu Nakashima4,5, Takeshi Kawamoto1,6 (1. N-BARD, Hiroshima Univ., 2. Dept. Mol. Biol. Biochem., Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 3. Dept. Pediatric Dent., Fac. Dent. Med., Airlangga Univ., 4. Dept. Stem Cell Biol. & Med., Grad. Sch. Biomed Health Sci, Hiroshima Univ., 5. Dept. Neph. Grad. Sch. Med., Univ. Yamanashi , 6. Writing Ctr., Hiroshima Univ.)
Comment()

[1P-591]Establishment and characterization of induced pluripotent stem cells from the large Japanese field mouse (Apodemus speciosus)

○Sumito Matsuya1, Hiroyuki Imai2, Naoki Iwamori3, Kaoru Fujino4, Yusuke Sakurai3, Toshiki Yoshimura3, Kenji Watanabe5, Wataru Fujii6, Yoichi Mizukami5, Masashi Tsujio1, Ken Takeshi Kusakabe2, Kiyoshi Kano4 (1. Kagoshima Univ., 2. Yamaguchi Univ. (Veterinary Anatomy), 3. Kyusyu Univ., 4. Yamaguchi Univ. (Biomedical Science - Developmental Genetics), 5. Yamaguchi Univ. (Institute of Gene Research), 6. Tokyo Univ.)
Comment()

[1P-593]In vivo and in vitro evaluation of developmental constraints caused by polyploidy in mouse embryos

○hiroyuki imai1, Sumito Matsuya2,3, Kaoru Fujino2, Muneyoshi Hyoto1, Kiyoshi Kano2, Takeshi Ken Kusakabe1 (1. Vet. Anat., Yamaguchi Univ., 2. Vet. Embryol., Yamaguchi Univ., 3. Vet. Anat., Kagoshima Univ.)
Comment()

[1P-594]Selection of Genomically and Epigenomically Stable Female iPS Cell Reference Lines

○Atsushi Izumi1,2 (1. Tokai University , 2. Kitasato University)
Comment()

[1P-595]Identification of Membrane Proteins Differentially Expressed Between Naive and Primed States in Human iPS Cells

○Atsushi Intoh1, Akira Kurisaki1 (1. Nara Institute of Science and Technology)
Comment()

[1P-596]Significance of PDGF-AA-PDGFRα signal axis in neural stem cell proliferation

○Risako Orita1, Noriko Okuno1, Masakiyo Sasahara1, Katsuyoshi Takata1, Seiji Yamamoto1 (1. Toyama Univ.)
Comment()

[1P-597]Role of transcription factor STAT3 and functional analysis of mutant STAT3 in mouse ES cells

○Shota Nakamura1, Atsushi Ueda2, Takashi Yokota3, Tadayuki Akagi1 (1. Fukuoka Institute of Technology, 2. Tokai Univ., 3. Kanazawa Univ.)
Comment()

[1P-598]Functional Analysis of the Effects of STAT3 Inhibitors on Self-Renewal in Mouse ES Cells

○Yuta Aoki1, Kanta Kajiwara2, Takeshi Matsuo1, Karin Kikuchi2, Miu Hamaguchi2, Tadayuki Akagi1,2 (1. Fukuoka Institute of Technology, 2. Fukuoka Institute of Technology Univ.)
Comment()

[1P-599]Comprehensive Analysis of Positional Identity and Developmental Dynamics in Human iPSC-Derived Limb Bud Mesenchymal Cells

○Kokoro Furutani1, Shodai Togo1, Tomoka Takao1, Tatsunori Osone1, Shigeo Otake1, Takeshi Takarada1 (1. Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
Comment()

[1P-600]Characterization of exosomes from mouse cortical bone-derived stem cells

○Norihiko Sasaki1, Kyojiro Kawakami1, Yoko Itakura1, Takayuki Fujita2, Shigeru Miyagawa3, Tomoaki Ishigami5, Hajime Kubo4, Yuri Miura1, Yumi Chiba6 (1. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Department of Physiology, Fukuoka University School of Medicine, 3. Department of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, 4. Cardiovascular Research Center, Lewis Katz School of Medicine, Temple Univer Sity, 5. Department of Cardiology, Yokohama City University Hospital, 6. Advanced Adult Nursing, Department of Nursing, Graduate School of Medicine, Yokohama City University)
Comment()

[1P-601]Trim61 enhances reprogramming into naïve iPS cells by regulation of the p53 pathway

○Daiki Haraguchi1, Keiichiro Kitagawa, Toshinobu Nakamura1 (1. Nagahama Institute of Bio-Science and Technology)
Comment()

[1P-602]Improved Prospective Isolation of Transplantable HSCs Using a Dual Reporter Strategy

○Taro Sakamaki1, Katsuyuki Nishi1,2, Akiomi Nagasaka1, Kay Sadaoka1, Junji Otani1, Masanori Miyanishi1 (1. Kobe University, 2. Stanford University)
Comment()

[1P-604]Extramachrochaetae is involoved in the regulation of the timing of neurogenesis and also that of neuronal specification.

Yuangchang Tsai1, Shoko Onuma2, Takuto Owada2, ○Takumi Suzuki1,2 (1. Dept. of Biol., Gradurate school of Sci. and Eng., Ibaraki Univ., 2. Dept. of Sci., College of Sci., Ibaraki Univ.)
Comment()

[1P-605]Elucidating the Epigenetic Regulatory Mechanisms Governing Mesodermal and Myogenic Differentiation of Stem Cells

○Terano Sakiko1, Suwada Takuya1, Hirakawa Hideki1, Tashiro Kosuke1 (1. Kyushu Univ.)
Comment()

[1P-606]Functional Analysis of Cell Adhesion Dynamics during Muscle Cell Differentiation

○Juri Tashima1, Yuri Kawabata1, Hideki Hirakawa1, Kosuke Tashiro1 (1. Kyushu Univ.)
Comment()

[1P-607]Effect of vitamin C on proliferation and differentiation of epidermal keratinocytes

○Yui Hiwatashi1,2, Nana Egawa1,2, Ayami Sato3, Yoshitaka Kondo1, Norikatsu Saito4, Hajime Ohsaawa4, Akihito Ishigami1,2 (1. Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Department of Biological Sciences, Tokyo Metropolitan University, 3. Department of Nutrition Science, Faculty of Health and Sports Science, Toyo University, 4. Risou Co., Ltd.)
Comment()

[1P-608]A Role for M-cadherin–Vangl2 Interaction in the Regulation of Skeletal Muscle Stem Cell Differentiation

○Tadahiro Nagaoka1, Erina Sasaki1, Sakiho Takagi1, Masashi Kishi2, Keisuke Hitachi1, Kunihiro Tsuchida1 (1. Fujita Health Univ., 2. NAIST)
Comment()

[1P-609]The lysosomal Ragulator complex controls the development of dendritic cells in bone marrow through inactivating Transcription factor EB

○Yutaka Muto1, Kohei Tsujimoto1, Atsushi Kumanogoh1 (1. Graduate School of Medicine, The University of Osaka)
Comment()

[1P-610]Effects of vitamin C-mediated regulation of peptidyl-arginine deiminase (PAD) expression on epidermal keratinization

○Nana Egawa1,2, Yui Hiwatashi1,2, Yoshitaka Kondo1, Ayami Sato3, Norikatsu Saito4, Hajime Ohsawa4, Akihito Ishigami1,2 (1. Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Department of Biological Sciences, Tokyo Metropolitan University, 3. Department of Nutritional Sciences, Faculty of Health and Sports Sciences, Toyo University, 4. Risou Co., Ltd.)
Comment()

[1P-611]Analysis of the molecular mechanisms regulating species-specific developmental timing

○Natsumi Matsumoto1, Ayako Isotani1, Toshiya Kokaji1, Noriaki Sasai1 (1. Division of Biological Science, Nara Institute of Science and Technology)
Comment()

[1P-612]Age-related accumulation of vitronectin, an inhibitory factor of myoblast differentiation, in skeletal muscle.

○Tomoka Katayama1, Ying Zeng2, Kenichi Mizutani2, Daiji Okamura1 (1. Dept. of Bioscience, Grad. Sch. of Agriculture, Kindai Univ., 2. Grad. Sch. Pharm., Kobe Gakuin Univ.)
Comment()

[1P-613]The Switching Mechanism of Differentiation Potential in Neural Stem Cells

○Minori Shigeta1, Takuma Shinozuka1, Noriaki Sasai1 (1. Nara Institute of Science and Technology)
Comment()

[1P-614(1AS-05-03)]A role for active protein degradation on the tempo of mouse and human neural differentiation

○Shota Nakanoh1, Loukik Doshi1, Lorena Garcia-Perez2, Chiara Azzi1, Hayley Carr1, Despina Stamataki2, Lu Yu1, David Oxley1, Simon Andrew1, James Briscoe2, Teresa Rayon1 (1. Babraham Institute, 2. The Francis Crick Institute)
Comment()

[1P-615(1AS-11-02)]Development and Characterization of Human Pancreatic Tuft Cells and Taste Cells Using Organoid Technology

○Tatsuya Kometani1, Kosuke Sakaguchi1, Hiroo Imai2, Hirofumi Fukushima4, Koji Kawaguchi3, Ken Iwatsuki1 (1. Dept. of Nutritional Science and Food Safety, Faculty of Applied Bioscience, Tokyo Univ. of Agriculture, 2. Center for the Evolutionary Origins of Human Behavior, Kyoto Univ., 3. Dept. of Oral & Maxillofacial Surgery, Tsurumi Univ. School of Dental Medicine, 4. Head and Neck Oncology Center, Showa Medical Univ.)
Comment()

[1P-616]Yuragi based hierarchical analysis and predictive modeling of system phase transitions in cellular states

○Rui Tang1,2, Hideaki Fujita3, Go Shioi2, Tomonobu M Watanabe2,3 (1. The University of Osaka, 2. Laboratory for Comprehensive Bioimaging, RIKEN Center for Biosystems Dynamics Research (BDR), 3. Department of Stem Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University)
Comment()

[1P-617]3D Printed Microdevices for Local Stimulation of iPS Cell Embryoid Bodies

○Yuma Abe1, Taro Toyoda2, Hidekuni Takao1, Kyohei Terao1 (1. Kagawa Univ., 2. Kyoto Univ.)
Comment()

[1P-618(1MS-06-02)]Biochemical properties of hypoxia-inducible factors in epidermal cell differentiation in a three-dimensional culture system.

○Kojin Kitadani1, Reina Sato1, Hideki Tatsukawa1, Tokuji Tsuji1, Kiyotaka Hitomi1 (1. Nagoya University Graduate School of Pharmaceutical Sciences)
Comment()

[1P-619]LSD1 Is an Epigenetic Gatekeeper Linking Metabolism and Stemness in Human Fetal Neural Stem Cells

○Masakazu Namihira1, Kazutoshi Murotomi1, Kazumi Hirano2, Kazutaka Araki3, Hiroko Ishitsuka1, Daisuke Miura1, Shinjiro Hino4 (1. Molecular Biosystems Research Institute, AIST., 2. Cellular and Molecular Biotechnology Research Institute, AIST., 3. Research Institute for Sustainable Chemistry, AIST., 4. Institute of Molecular Embryology and Genetics, Kumamoto Univ.)
Comment()

[1P-620]Discovery of intracellular thermal signaling mechanisms in neuronal differentiation

○Shunsuke Chuma1, Kohki Okabe1, Yoshie Harada2,3 (1. Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2. WPI-PRIMe, The Univ. Osaka, 3. QIQB, The Univ. Osaka)
Comment()

[1P-621]Elucidation of the Mechanism by which CaMKII Maintains Fast-Twitch Fibers in Skeletal Muscle

○Hikaru Iwase1, Ryouka Thukahara1, Takuma Kunieda2, Yuka Itihasi1, Yasuo Utida2, Tomoharu Yasuda1, Yasuo Kitajima1 (1. Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 2. Department of Molecular and System Pharmacology, Graduate School of Biomedical and Health Sciences, Hiroshima University)
Comment()

[1P-622]Involvement of ATF5 mRNA upstream open reading frame on olfactory sensory neuron differentiation

○Sakiko Yamaguchi1, Haruo Nakano1, Sanetoki Koide1, Shuya Yoshida1, Mariko Umemura1, Shigeru Takahashi1, Yuji Takahashi1, Yasuhiro Shinkai1 (1. Tokyo Univ. of Pharm. and Life Sci.)
Comment()

[1P-623]Functional analysis of Dve in Drosophila cardiomyocytes

○Taichi Urabe1, Miku Shiroo1, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life, Natl. Sci. Tech., Okayama Univ.)
Comment()

[1P-624]Imprinted Gene with Reduced Expression in the Fetal Brain Due to Paternal Factors: Implications for Missing Heritability

○Yui Takahashi1, Hanae Tomaru1, Sara Ebrahimiazar1, Shyu Manabe1, Haruka Endo1, Takako Kikkawa1, Noriko Osumi1 (1. Tohoku University)
Comment()

[1P-625]Analysis of nuclear dynamics in Xenopus ectodermal cells

○Yumeko Satou-Kobayashi1, Makoto Asashima1 (1. Teikyo University・ACRO)
Comment()

[1P-626]Mitochondrial Aminopeptidase Metap1D Inhibition Impairs Myogenic Differentiation

○Shion Osana1,2, Chengta Tsai1, Chi-Fang Hsu1, Reiya Murakami2, Haruya Uchibori1, Masaki Kaneko1, Katsuhiko Hata1, Yutaka Kano2 (1. Kokushikan university, 2. The University of Electro-Communications)
Comment()

[1P-627]STAT3 signalling drives tissue expansion and axial elongation through WNT pathway

○Takuya Azami1, Jennifer Nichols1 (1. The University of Edinburgh)
Comment()

[1P-628]Glutamine-induced Metabolic Dysregulation During Early Embryogenesis Association with Metabolic Disorder

○Norermi Firzana Alfian1, Satoshi Kishigami2,3,4, Yui Maruhashi1, Masahiro Horizoe1 (1. Department of Integrated Applied Life Science, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, University of Yamanashi, Kofu, Yamanashi, Japan, 2. Faculty of Life and Environmental Sciences, University of Yamanashi, Kofu, Yamanashi, Japan, 3. Center for Advanced Assisted Reproductive Technologies, University of Yamanashi, Kofu, Yamanashi, Japan, 4. Advanced Biotechnology Center, University of Yamanashi, Kofu, Yamanashi, Japan)
Comment()

[1P-629]Comparative analysis of pro-apoptotic genes in mouse early embryos

○Yuzuki Goto1, Takuto Yamamoto1, Masahiro Sakata1, Satoshi Mashiko1, Daiki Shikata1, Shinnosuke Honda1, Naojiro Minami1, Shuntaro Ikeda1 (1. Dept. of Appl. Bio. Sci., Grad. Sch. of Agr., Univ. of Kyoto)
Comment()

[1P-630]Understanding the spatiotemporal control of the mouse early embryo proteome

○Ayaka Kakihara1, Atsushi Hatano1, Masaki Matsumoto1 (1. Dept. Omics Sys. Biol., Grad. Sch. Med. Dent. Sci., Niigata Univ.)
Comment()

[1P-631]Effects of chloroquine exposure of mouse preimplantation embryos on MEM pups and adults

○Kaname Sato1 (1. Department of Integrated Applied Life Science, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, University of Yamanashi)
Comment()

[1P-632]Initiation of apoptosis is dependent on mitochondrial restruction after MBT in early embryogenesis of Xenopus laevis

○Shuichi Ueno1, Kohei Nakahara1, Natsumi Yano2 (1. Yamaguchi Univ., Grad. Sch. of Sci. and Tech. for Innov., 2. Yamaguchi Univ., Fac. of Sci., Biol.)
Comment()

[1P-633]FGF8 and its Intracellular Signaling Pathway Regulate Stage-Specific Meckel’s Cartilage Formation During Early Mandibular Morphogenesis in Mice.

○HE QI1, FUMIE Terao2, DIYAA Al Akel1, KEIGO Yoshizaki2, ICHIRO Takahashi2 (1. Section of Orthodontics and Dentofacial Orthopedics, Graduate School of Dent al Science, Kyushu University, 2. Section of Orthodontics and Dentofacial Orthopedics, Faculty of Dental Science, Kyushu University)
Comment()

[1P-634]Elucidation of molecular mechanisms on Glis3-mediated zygotic genome activation

○Tomomi Shimada1, Toshinobu Nakamura1 (1. Nagahama Institute of Bio-Science and Technology)
Comment()

[1P-635]Transcriptional reprograming of endangered animal nuclei with applied Nuclear Transfer method

○IKEDA Koyo1, KADONO Risa2, Christopher Penfold3, INOUE Akihiro1, NISHIZAKI Shuntarou1, MIYAGAWA Yasuki1, MORI Ryunosuke2, YAMAUCHI Nobuhiko1, ANZAI Masayuki4, MIYAMOTO Kei1 (1. Kushu Univ. Agriculture , 2. Kindai Univ. BOST, 3. Department of Physiology・University of Cambridge, 4. Institute of Advanced Technology, Kindai University)
Comment()

[1P-636]CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates

Nikola Sekulovski1, Amber Carleton1, Anusha Rengarajan1, Chien-Wei Lin1, Maliha Kabir1, Lauren Juga1, Allison Whorton1, Lauren Elberfeld1, Jenna Wettstein1, Jenna Schmidt2, Thaddeus Golos2,3,4, ○Kenichiro Taniguchi1 (1. Medical College of Wisconsin, 2. Wisconsin National Primate Research Center, 3. University of Wisconsin - Madison School of Medicine, 4. University of Wisconsin - Madison School of Veterinary Medicine)
Comment()

[1P-637]Exploration of transposon-derived promoters functioning in mammalian embryos using long-read sequencing

○Saki KAWAKAMI1, Koichi KITAO2, Shuntaro IKEDA1, Shinnosuke HONDA1 (1. Graduate School of Agriculture, Kyoto University, 2. RIKEN Center for Integrative Medical Sciences)
Comment()

[1P-638]Toward a Reconstruction of Zygotic Genome Activation

○Aoi Ito1, Kengo Osada1, Takashi Ishiuchi1 (1. University of Yamanashi)
Comment()

[1P-639]Transcription Factor 23 is an Essential Determinant of Murine Term Parturition

○Hossam H Shawki1, Fatma M. Minisy2, Tsubasa Fujita1, Ahmed M. Moustafa1, Rumeysa Sener1, Youske Nishio1, Issei S Shimada1, Shinji Saitoh1, Mayumi Sugiura Ogasawara1, Hisashi Oishi1 (1. Nagoya City University -Japan, 2. National Research Centre -Egypt)
Comment()

[1P-640]Novel sperm-expressed Ig-like domain type I transmembrane protein is required for sperm-egg interaction in C.elegans

○Kohdai Nakajima1, Hitoshi Nishimura2, Tetsuya Higashiyama3, Benjamin Podbilewicz4 (1. Keio Univ., 2. Setsunan Univ., 3. UTokyo, 4. Technion)
Comment()

[1P-641]Ovarian tachykinin signaling system induces the growth of secondary follicles during the gonadotropin-independent process

○Tsuyoshi Kawada1, Masato Aoyama2,3, Shin Matsubara1, Tomohiro Osugi1, Tsubasa Sakai1, Shinji Kirimoto1, Satsuki Nakaoka1, Yuki Sugiura4, Keiko Yasuda2, Honoo Satake1 (1. Suntory Foundation for Life Sciences, 2. Nara Women's University, 3. NIPRO CORPORATION, 4. Kyoto University)
Comment()

[1P-642]HDA-2/HDAC3 regulates apoptotic germ cell clearance and distal tip cell migration via positively regulating CED-12 in C. elegans

○Roku Arima1, Takuma Unno1, Arashi Ezaki1, Hisashi Takatsuka1, Fangzheng Li1, Kousuke Matsumoto2, Yoichi Shinkai3, Motomichi Doi3, Masahiro Ito1,2, Yukihiko Kubota2 (1. Graduate School of Life Sciences, Ritsumeikan University, 2. College of Life Sciences, Ritsumeikan University, 3. Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology)
Comment()

[1P-643]Analysis of the Molecular Function of Squash, a Crucial piRNA Component for Germline Genome Integrity

○XIN XU1, Ritsuko Suyama1, Taichiro Iki1, Shinichi Kawaguchi1, Toshie Kai1 (1. Osaka University)
Comment()

[1P-644(1PS-10-06)]Pharmacologic and genetic analyses of a C. elegans model for temperature-sensitive male infertility

○Yoshihiro Shimada1, Ayaka Yoshida1, Suzuka Nomura1, Nana Kanazawa1, Kentaro Kawai2, Yukiko Karuo2, Jun Adachi3, Arata Honda4, Jundal Kim5, Akiyoshi Fukamizu6, Masaaki Omote2, Hitoshi Nishimura1 (1. Dept. Lif. Sci., Fac. Sci. Eng., Setsunan Univ., 2. Fac. Pharm. Sci., Setsunan Univ., 3. NIBN(PDD), 4. Ctr. Dev. Adv. Med. Tech., Jichi Med. Univ., 5. Inst. Natl. Med., Toyama Univ., 6. TARA Ctr., Tsukuba Univ.)
Comment()

[1P-645]Interaction between mural granulosa cells and cumulus cells during ovulation after LH surge based on transcriptome analysis

○Amon Shiroshita1, ISAO TAMURA1, MARINA ITO1, TOSHIHIDE YONEDA1, TAISHI FUJIMURA1, NORIHIRO SUGINO1 (1. Yamaguchi university school of medicine)
Comment()

[1P-646]Development of structure-based site-specific antisera against wild boar targeting Zona Pellucida proteins

○Lica Yakushiji1, Makoto Asano2, Masaki Takasu3, Akie Iwata4, Aya Ohtsu4, Naoto Yonezawa1 (1. Chiba University, 2. Gifu University, 3. Gifu University Institute of advanced study, 4. Chiba University Faculty of Science)
Comment()

[1P-647]Exploring germ cell-secreted factors in medaka

○Motonari YOKOO1, Mina Hirata1, Kazuya Ichihara1, Akinobu Matsumoto1, Mariko Kikuchi1, Minoru Tanaka1 (1. Division of Biological Science, Graduate School of Science, Nagoya University)
Comment()

[1P-648]Adaptation to Harsh Environment via Reproductive Non-coding RNAs

○Ryusei Sone1,2, Reina Komiya1,3 (1. RIKEN, 2. The University of Tokyo, 3. Okinawa Institute of Science and Technology)
Comment()

[1P-649]Elucidation of the molecular mechanisms underlying the establishment of bivalent states of meiosis-related genes

○Kousuke Uranishi1, Ayumu Suzuki2, Masataka Hirasaki1, Masazumi Nishimoto1, Akihiko Okuda1 (1. Saitama Medical University, 2. Tsukuba University)
Comment()

[1P-650]Intravaginal administration of progesterone for the synchronization of the estrous cycle in mice

○Ban Sato1, Yutaka Yamashita1, Masahiro Sato2, Kenji Miyado3, Natsuko Kawano1 (1. Dept. of Life Sci. Agr. Meiji Univ. , 2. Dept. of Genome. Med. NCCHD, 3. Dept. of Rep.Biol. NCCHD)
Comment()

[1P-651]Morphological and histological analysis of developmental disorders seen in reproductive tract of B6N-XYPOS mice

○Honoka Kwai1, Toshifumi Yokoyama1, Chihiro Inuzuka1, Sachika Kuramoto1, Hoshikawa Yaichi1, Youhei Mantani1, Takanori Miki2, Nobuhiko Hoshi1 (1. Kobe University, 2. Kagawa University)
Comment()

[1P-652]Tracking Telomerase Template RNA (AtTR) Using RNAi in Arabidopsis thaliana

○Yosei Fujita1, Saori Miyazaki2 (1. Shizuoka Univ., 2. Shizuoka Univ.)
Comment()

[1P-653]Analysis of sexual dimorphism in reproduction among carriers of balanced reciprocal chromosomal translocations

○Makiko Tsutsumi1, Fuminori Matsushima1, Atefeh Joudaki1, Hiroki Kurahashi1 (1. Fujita Health University)
Comment()

[1P-654]TdIF1 controls gene expression through histone deacetylation in mouse spermatogenesis

○Yuto Yamada1,2,3, Kai Otsuka1,2,3, Ai Ikuyo1,2,3, Tomohiro Iguchi4, Hisao Masai4, Satoshi Namekawa5, So Maezawa1,2,3 (1. Dept. of Appl. Biol. Sci., Facl. of Sci. and Tech., Tokyo Univ. of Sci., 2. Div. of Aging Biol., RIST, Tokyo Univ. of Sci., 3. Div. of Med. Data Sci., RIST, Tokyo Univ. of Sci., 4. Genome Dynamics , TMiMS., 5. Dept. of Microbiol. and Mol. Genet., UC Davis)
Comment()

[1P-655]Gametogenesis of germ cells derived from haploid embryos in medaka (Oryzias latipes)

○Moe Takeuchi1, Takafumi Fujimoto1, Toshiya Nishimura1 (1. Hokkaido University)
Comment()

[1P-656]MAX is a crucial regulator for the initiation of meiosis in murine primordial germ cells

○Ayumu Suzuki1,2, Kousuke Uranishi2, Nishimoto Masazumi2, Mizuno yousuke2, Satoru Takahashi3, Akihiko Okuda2, Seiya Mizuno1 (1. Dept. of Anim sci., Univ. of Tsukuba, 2. Saitama Med. Univ., 3. AnaEmb, Med. Univ. of Tsukuba)
Comment()

[1P-658]Thermal adaptation-related functions of HP6 in Drosophila melanogaster

○Masanori Mukai1,2, Junki Watanabe2, Yuto Okumura1, Mika Toyoda, Hayato Kikuoka2, Takane Imayasu1, Shuhei Tuji1 (1. Dept. of Biol., Fac. of Sci. and Eng., Konan Univ, 2. Grad. Sch. of Nat. Sci., Konan Univ.)
Comment()

[1P-659]Blockchain-Based System for Managing and Sharing Research Records

○Daigo Okada1,2,4, Ken-Ichi Tezuka1,3 (1. Department of Stem Cell and Regenerative Medicine, Graduate School of Medicine, Gifu Univ., 2. Institute for Advanced Study, Gifu Univ., 3. COMIT, Gifu Univ., 4. National Institute of Informatics)
Comment()

[1P-660]A scalable two-step genome editing strategy for generating full-length gene-humanized mice

○Jumpei Taguchi1, Manabu Ozawa1 (1. Core Laboratory for Developing Advanced Animal Models, The Institute of Medical Science, The University of Tokyo)
Comment()

[1P-661]Enhancement of epidermal barrier function by Rosae multiflorae fructus extract and identification of its active components

○Sae Asayama1, Tami Igarashi2, Masayuki Yagi2, Yoko Niki3, Hideya Ando4, Masamitsu Ichihashi5, Ken-ichi Mizutani1 (1. Fac. Pharm., kobegakuin Univ., 2. Rosette Co., Ltd., 3. Sch. Pharm. Sci., Mukogawa Women’s Univ., 4. Fac. Life Sci., Okayama Univ. of Sci., 5. Shuhakukai Med. Corp.)
Comment()

[1P-663]Temperature-dependent sexual differentiation mechanism in Japanese eel (Anguilla japonica)

○Takae Hirasawa1, Yuko Takayama1, Shigeo Uchino1, Osamu Yoshida1, Yi Qing Ong1, Kanna Mikami1, Ruxin Li1, Yi Chen Lee1, Hiroshi Kobayashi (1. Teikyo Univ)
Comment()

[1P-664]Development of Hybrid Cryogel Filler for Tissue Regeneration

○Kyoung-ha So1 (1. Seoul National University)
Comment()

[1P-665]Simultaneous knock-in of multifunctional tags and a fluorescent protein into zebrafish sox1a/sox1b

○Yuto Yamamoto1, Yusuke Kamachi1 (1. Kochi Univ. Tech.)
Comment()

[1P-666]Endoplasmin as a Novel Modulator of Angiogenesis through ERK Signaling

○Soo Min Choi1 (1. Dong A university)
Comment()

[1P-667]Functional genome analysis of Paramecium isolated from brackish water in the frigid zone and its symbiotic bacteria

○Masato Tachibana1, Shintaro Maeno1, Hideo Dora2, Kenta Watanabe3, Takashi Shimizu3, Masanori Hashino4, Risa Someno4, Masahisa Watarai3 (1. Org. Res. Ini, Yamaguchi Univ., 2. Shizu Ins. Ana. Cen. Shizuoka Univ., 3. Joi. Fac. Vet. Med. Yamaguchi Univ., 4. PGC NIID)
Comment()

[1P-668]How to use organoid culture system in the study of gut microbiota

○Nobuo Sasaki1 (1. Gunma University)
Comment()

[1P-669]A biologically plausible mechanism for balancing heterogenous populations

○Tomoyuki Yamaguchi1 (1. Research Institute, Nozaki Tokushukai Hospital)
Comment()

[1P-670]Effects of exogenous histidine on pyochelin production by Pseudomonas protegens

○Masayo Ogiso1, Tomohiro Morohoshi2, Kasumi Takeuchi1 (1. NIAS・NARO, 2. Grad.Sch.Reg.Devel.Creativity, Utsunomiya Univ.)
Comment()

[1P-671]Drug screening for radical cure of Toxoplasmosis by preventing parasite reactivation

○Hironori Bando1, Md. Forhad Hossain1 (1. Asahikawa Medical University)
Comment()

[1P-672]Understanding the Life Cycle of Trichinella through Transcriptome Analysis

○Jun-ichi Takeda1, Sukhonthip Khueangchiangkhwang2, Zhiliang Wu2, Yoichi Maekawa1,2 (1. COMIT, Institute for Advanced Study, Gifu Univ., 2. Parasitology and Infectious Diseases, Graduate School of Medicine / School of Medicine, Gifu Univ.)
Comment()

[1P-673]Effects of Co-housing with Males on the Gut Microbiota of Female Teleogryllus occipitalis

○Kazuya Hirata1, Takeshi Suzuki2,6, Kei Yura3,1, Toru Asahi1,4, Kosuke Kataoka4,5,6 (1. Dept. of Adv. Sci. Eng., Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 2. Dept. of Bio-App. and Sys. Eng., Grad. Sch. of Tokyo Univ. of Agric. and Tech. , 3. Fac. of Core Res., Ochanomizu Univ. , 4. Dept. of Comp. Res. Org., Waseda Univ., 5. Grad. Sch. Eng., Tokyo Univ. of Agric. and Tech., 6. Dept. of Adv. Interdisciplinary Sci., Grad. Sch. of Tokyo Univ. of Agric. and Tech.)
Comment()

[1P-674(1AS-03-03)]Additional perturbations of Notch signaling rescue synchronized oscillations in the Lfng-knockout segmentation clock

○Ayumi Goto1,2, Akihiro Isomura1, Ryoichiro Kageyama1 (1. RIKEN, 2. Kyoto university)
Comment()

[1P-675]Deletion of the clock gene Bmal1 in Dkk3-expressing chondrocytes disrupts skeletal joint homeostasis and induces degeneration

○XINZHE WU1, Atsushige Ashimori1,2, Kiminori Yukata3, Fumiaki Higashijima1, Takuya Yoshimoto1, Ayano Sakuma1, Waka Hamada1, Junki Sunada1, Ren Aoki1, Masanori Mikuni1, CHAOYONG WANG1, DINGLIANG XU1, Ken’ichiro Hayashi1, Shohei Uchi1, Shinji Hirano1, Makiko Wakuta1, Takahisa Furukawa4, Shigeki Shimba5, Hidenori Suzuki3, Takashi Sakai3, Kazuhiro Kimura1,2 (1. Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, 2. Research Institute for Cell Design Medical Science (RICeD), Yamaguchi University, 3. Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 4. Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, 5. Laboratory of Health Science, School of Pharmacy, Nihon University)
Comment()

[1P-677]Functional analysis of ADNP, a gene associated with Autism Spectrum Disorder, in the transcriptional regulation of circadian rhythm genes

○Ryoshi Hosokawa1, Hotaka Fukushima1, Takanobu Nakazawa1, Daiki Miura1 (1. Tokyo University of Agriculture Graduate School of Life Sciences Department of Bioscience)
Comment()

[1P-678]Analysis of Cortical Structural Abnormalities Caused by Histone H4C Mutations in TEBIVANED Syndrome

○Haruna Nagasawa1, Kaneyasu Nishimura2, Sayaka Tojima1, Tadashi Nomura1,3 (1. Applied Biology, Kyoto Institute of Technology, 2. Graduate School of Brain Science, Doshisha Univ, 3. Center for Social and BioMedical Engineering, Kyoto Institute of Technology)
Comment()

[1P-679]Effects of NGF and mutant CRMP4 on CRMP4–RhoA binding involved in neurite formation

○Nanase Kamei1, Yui Nakano1, Syota Ishiguro1, Yuka Tanaka2, Ritsuko Ohtani-Kaneko1,2, Sakura Chujo3, Etsuko Katoh3 (1. Toyo University Graduate School of Life Science, 2. Toyo University of Life Science, 3. Toyo University Graduate School of Food and Nutritional Sciences)
Comment()

[1P-680]Function analysis of C16orf95, a gene associated with human-specific globular skull

○Tamaki Tanaka1, Kaneyasu Nishimura2, Sayaka Tojima1, Tadashi Nomura1,3 (1. Applied Biology, Kyoto institute of Technology, 2. Graduate School of Brain Science, Doshisha Univ, 3. Center for Social and BioMedical Engineering, Kyoto Institute of Technology)
Comment()

[1P-681]Are Tbr2-positive cells in non-mammalian cerebrum really intermediate progenitor cells?

○Taito Tsujino1, Shoyo Tainaka1, Sayaka Tojima1, Tadashi Nomura1,2 (1. Applied Biology, Kyoto Institute of Technology , 2. Center for Social and BioMedical Engineering, Kyoto Institute of Technology)
Comment()

[1P-682]Elucidation of molecular pathogenesis of with pentosidine accumulation

○Azuna Ozawa1,2, Kazuya Toriumi2, Shimada Tadayuki3, Takuya Tomita4, Yasushi Saeki4, Mitsuhiro Miyashita5, Makoto Arai2 (1. Niigata University Graduate school of Medical and Dental Sciences Molecular and Cellular Medicine Major, 2. Tokyo Metropolitan Institute of Medical Science Schizophrenia Research Project, 3. Tokyo Metropolitan Institute of Medical Science Child Brain Project, 4. Division of Protein Metabolism, The Institute of Medical Science, The University of Tokyo, 5. Tokyo Metropolitan Institute of Medical Science Research Center for Social Science & Medicine (RCSSM) Unit for Mental Health Promotion)
Comment()

[1P-683]Evolutionary conservation and diversification of molecular mechanisms underlying radial neuronal migration

○Akiyoshi Sekiguchi1, Sayaka Tojima1, Tadashi Nomura1,2 (1. Applied Biology, Kyoto Institute of Technology, 2. Center for Social and BioMedical Engineering, Kyoto Institute of Technology)
Comment()

[1P-684(1AS-12-04)]Migration and distribution mechanisms in developing astrocytes

○Shun Takano1, Michio Miyajima1,2, Keiko Morimoto1, Koya Takahashi3, Noriko Hiroi1,3, Hitomi Sano1, Hidenori Tabata1,4, Kazunori Nakajima1 (1. Dept. Anat. Keio Univ. Sch. Med. , 2. PRESTO, JST, 3. Fac. Engineering, Kanagawa Inst. Tech., 4. Dept. Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center)
Comment()

[1P-685]Discovery of primary cilia elongation phenomenon as an ultrasound response in 1321N1 cells derived from human astrocytoma

○Shun Yokoshima1, Satoka Kasai1, Kazumi Yoshizawa1, Akiyoshi Saitoh2, Satoru Miyazaki3 (1. Lab. of Disease Pharmacology, Dept. of Pharm. Sci., Fac. of Pharm. Sci. , Tokyo Univ. of Sci., 2. Lab. of Pharmacology, Dept. of Pharm. Sci., Fac. of Pharm. Sci. , Tokyo Univ. of Sci., 3. Lab. of Bioinformatics, Dept. of Pharm. Sci., Fac. of Pharm. Sci. , Tokyo Univ. of Sci.)
Comment()

[1P-686]Morphological analysis of pyramidal neurons in the somatosensory neocortex in autism model mice.

○Momoka Kawabata1, Masanori Tsurugaya2, Kaede Yamagishi2, Minami Ishizaka2, Takae Hirasawa1,2, Shigeo Uchino1,2 (1. Teikyo Univ. Grud school, 2. Teikyo Univ.)
Comment()

[1P-687]Analysis of neural activity in autism model mice based on c-Fos expression

○Naoto Yamazaki1, Masanori Tsurugaya2, Shuya Kobori2, Kaede Yamagishi2, Shigeo Uchino1,2 (1. Teikyo Univ. Grad school, 2. Teikyo Univ.)
Comment()

[1P-688]Effects of maternal 4-tert-Octylphenol exposure on the olfactory system

○Dong Hun Lee1, Hyun Seung Shin1, Yun Hee So1, Do Hyo Lim1, Ba Da Cho1, Eui-Man Jung1 (1. Pusan National University)
Comment()

[1P-689]Prenatal exposure to polystyrene nanoparticles induces neuroimmune dysregulation in the adult mouse brain

○YunHee So1, Hyun Seung Shin1, Dong Hun Lee1, Do Hyo Lim1, Ba Da Cho1, Eui-Man Jung1 (1. Pusan National University)
Comment()

[1P-690]In vivo genome editing approach to verify axonal factor involving Ranvier node spacing in the sound localization circuit

○Mai Horioka1,2, Ryo Egawa2, Hiroshi Kuba2 (1. Sch Med, Nagoya Univ, 2. Grad Sch Med, Nagoya Univ)
Comment()

[1P-691]A library screening revealed small molecule inhibitors promoting dendritic differentiation of cerebellar Purkinje cells

○Masahiko Tanaka1, Shoki Hashimoto1, Naohide Hirashima1 (1. Dept. Cell. Biosphys., Grad. Sch. Pharmaceut. Sci., Nagoya City University)
Comment()

[1P-692]The effects of maternal stress on habenular development

○Hiromu Nakano1, Keishi Takeda1, Takashi Fukushima1, Rina Nakano1, Hitoshi Morita1, Satoshi Goto1, Maiko Higuchi1 (1. Rikkyo University)
Comment()

[1P-693]Transgenerational epigenetic effects from Fmr1 mutant fathers to offspring

○Haruka Endo1, Sara Ebrahimiazar1, Takako Kikkawa1, Noriko Osumi1 (1. Department of Developmental Neuroscience, Tohoku University Graduate School of Medicine)
Comment()

[1P-694]Developmental and molecular impairments relevant to ube3a mutation in zebrafish

○Godfried Tchetonnougbo Dougnon1, Lana Rummel2, Hideaki Matsui1 (1. Niigata University, 2. University of Victoria)
Comment()

[1P-695]Mechanisms by which maternal stress affects embryonic brain development

○Chinami Mogi1, Riku Kanai1, Ryuta Sasaki1, Maiko Higuchi1 (1. Rikkyo University)
Comment()

[1P-696]Cortex-specific deletion of the vitamin C transporter Slc23a2 alters behavior via epigenome dysregulation

○Saya Mizuno1, Hiroki Mabuchi1, Akira Kamiyoshi1, Rui Sakaki1, Mayumi Higuchi1, Fumihito Miura2, Hiromitsu Araki3, Kimi Araki4, Shota Katori1, Takeshi Yagi1, Noriyuki Sugo1 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Life Science Data Research Center, Graduate School of Frontier Sciences, the University of Tokyo, 3. Kyushu University Graduate School of Medical Sciences, 4. Institute of Resource Development and Analysis, Kumamoto University)
Comment()

[1P-697]Generation of a triple tag knock-in mouse to visualize precise protein localization patterns for type II classic cadherins during brain development

○Mayuko Hotta1,2, Yukiko U Inoue1, Junko Asami1, Mikio Hoshino1, Takayoshi Inoue1 (1. National Institute of Neuroscience, 2. Tokyo University of Agriculture and Engineering Graduate School of Engineering)
Comment()

[1P-698]Activity-Dependent Translational Dynamics of Ribosomal Proteins

○Akihiro Sasaya1, Masaki Kato2, Shu Kondo2, Hiromu Tanimoto1 (1. Tohoku Univ., 2. TUS)
Comment()

[1P-699]RP58-CtBP1 complex regulates neuronal migration and maturation in developing cerebral cortical neurons

○Katsuko Takasawa1, Shinobu Hirai1, Sayaka Hirai1, Mayumi Shindo1, Hiroko Shimbo1, Haruo Okado1, Chiaki Maruyama1 (1. Developmental Neuroscience Project, Department of Brain & Neurosciences, Tokyo Metropolitan Institute of Medical Science, 2. Brain Metabolism Group, Tokyo Metropolitan Institute of Medical Science, 3. Neural Development Project, Tokyo Metropolitan Institute of Medical Science, 4. Protein Analyses, Tokyo Metropolitan Institute of Medical Science)
Comment()

[1P-700]Calcium imaging analysis of synchronous neuronal activity in the mouse embryonic neocortex

○Akihito Shinohara1,2, Yasuhiro Matsumura1, Kimiko Fukuda2, Chiaki Ohtaka-Maruyama1,2 (1. Developmental Neuroscience Project, Tokyo Metroploitan Institute of Medical Science, 2. Developmental Biology, Department of Biological Sciences, Tokyo Metropolitan University)
Comment()

[1P-701]Establishment of a novel G4 genome profiling method

○Kenta Kinjo1, Kenta Kudo1, Norifumi Shioda1 (1. Kumamoto University, Institute of Molecular Embryology and Genetics, Department of Genomic Neurology)
Comment()

[1P-702]Development of a system for off-target repression in recombinase-dependent gene expression vectors

○Shigeki Kato1, Natsuki Matsushita2, Kazuto Kobayashi1 (1. Fukushima Med. Univ., 2. Aichi Med. Univ.)
Comment()

[1P-703]Temperature survival strategy of C. elegans utilizing neuro-intestinal correlations related to temperature stress response and acclimation

○Yukina Mori1, Akihisa Fukumoto1, Misaki Okahata1, Toru Miura1, Yohei Minakuchi2, Atsushi Toyoda2, Akane Ohta1, Atsushi Kuhara1,3 (1. Laboratory of Molecular and Cellular Regulation Graduate school of Natural Science Konan University, 2. National Institute of Genetics, Japan, 3. PRIME, AMED)
Comment()

[1P-705]Temperature-sensitive GPCR involved in heat tolerance in the C. elegans

○Shiori Mototake1,2,3, Yuki Sato1,2,3, Kohei Ohnishi1,2,3, Tohru Miura1,2,3, Akane Ohta1,2,3, Atsushi Kuhara1,2,3,4 (1. Dept. Biol., Facul. Sci & Engineer. Konan Univ., 2. Dept. Biol. Grad. Sch. Sci. Konan Univ., 3. Inst. of Integral NeuroBiol. Konan Univ., 4. PRIME AMED)
Comment()

[1P-706(1PS-03-05)]Involvement of innate immunity in age-dependent memory impairment in Drosophila

○Momoko Hoshi1, Akari Yuki2, Kotomi Onuki1, Aoi Yanagihara2, Motoyuki Itoh1, Ayako Tonoki1 (1. Graduate School of Pharmaceutical Sciences, Chiba University, 2. Faculty of Pharmaceutical Sciences, Chiba University)
Comment()

[1P-707]Mechanisms of Cold Tolerance Acquisition under Starvation in C. elegans and Identification of Novel Factors through Evolution Analysis

○Seiya Kamino1, miina Hujisawa1, Atsushi Doi2, Hideki Hirakawa2, Akane Ohta1, Atsushi Kuhara1,3 (1. Laboratory of Molecular and Cellular Regulation Graduate school of Natural Science Konan University , 2. Graduate School of Agriculture, Kyushu University, Graduate School of Biomedical Defense, Kyushu University, 3. PRIME, AMED)
Comment()

[1P-708(1PS-10-07)]Dissecting menopause-related neuroendocrine signals using C. elegans: Focusing on sexual dimorphism and temperature-responsive behavior

○Moonsun Jang1,2, Hironori J. Matsuyama3,2, Kotaro D. Kimura1, Ikue Mori2,4 (1. Nagoya City University, 2. Nagoya University, 3. Toyama Prefectural University, 4. Chinese Institute for Brain Research, Beijing)
Comment()

[1P-709]Nwd2 deficiency leads to hyperactivity and social behavioral abnormalities via kcnip1 upregulation

○Hayato Ogawa1, Misaki Kato1, Seiya Yamada1,2, Shin-ichi Sakakibara1 (1. Laboratory for Molecular Neurobiology, Faculty of Human Sciences, Waseda University, 2. Neuroscience Center, HiLIFE - Helsinki Institute of Life Science, University of Helsinki)
Comment()

[1P-711]Temporal dynamics of CREB-dependent transcription in Drosophila mushroom body neurons through learning

○Takehito Satoh1, Takaomi Sakai1 (1. Tokyo Metropolitan University)
Comment()

[1P-712]Role of MTMR2/mtm, the causative gene of CMT4B1, in the Drosophila nervous system

○Aya Hitomi1, Kazuki Shibutani1, Hideki Yoshida1 (1. Kyoto Institute of Technology Graduate School of Science and Technology)
Comment()

[1P-713]The genetic bases of left-right polymorphisms in Drosophila brain and their effects on mating behavior

○Wai Cheng Wong1, So Sakamura2, Yoshida Tomoki1, Yoshitake Eita1, Komomo Suyama1, Jinjing Pan3, Hoso Masaki3, Kosei Sato4, Masato Yamamichi5,6, Kenji Matsuno1 (1. The University of Osaka, 2. University of Hyogo, 3. Waseda University, 4. National Institute of Information and Communications Technology, 5. National Institute of Genetics, 6. SOKENDAI (The Graduate University of Advanced Studies))
Comment()

[1P-714]Top2b hypomorphic mice display a complex behavioral abnormalities

○Xianghe Song1,2, Yumiko Hatanaka2, Hiroyuki Sasanuma3, Hideya Kawaji4, Chiaki Maruyama1,2, Kimiko Hukuda1 (1. Tokyo Metropolitan University, Graduate School of Science, Department of Life Sciences, 2. Tokyo Metropolitan Institute of Medical Science, Developmental Neuroscience Project, 3. Tokyo Metropolitan Institute of Medical Science, Genome Dynamics Project, 4. Tokyo Metropolitan Institute of Medical Science, Research Center for Genome & Medical Sciences)
Comment()

[1P-715]Glutamate signaling mediates light intensity-dependent phototransduction in the nematode Pristionchus pacificus

○Keimei Ko1, Kenichi Nakayama2, Aya Manabe1, Takahiro Chihara1, Misako Okumura1 (1. Graduate school of Integrated Sciences for Life, Hiroshima University, 2. Department of Cell Biology and Center for Cell Dynamics, Johns Hopkins University School of Medicine)
Comment()

[1P-716]Genetic screening suggests 7TMIC proteins as candidate photoreceptors in the nematode Pristionchus pacificus

○CHI SHURAN1, Nakayama kenichi2, Watanabe Ryo1, Chihara Takahiro1, Okumura Misako1 (1. Hiroshima university, 2. Johns Hopkins University)
Comment()

[1P-717]Higher-order neural circuits controlling intersegmental coordination in axial locomotion

○Takaki Seki1, Maarten Zwart2,3, Hiroshi Kohsaka4,5, Akinao Nose1,5 (1. Dept Phys, Grad Sch Sci, Univ Tokyo, 2. Sch Psychol & Neurosci, Univ St Andrews, 3. Ctr Biophoton, Univ St Andrews, 4. Grad Sch Informat & Engn, Univ Electro Commun, 5. Dept Complex Sci & Engn, Grad Sch Frontier Sci, Univ Tokyo)
Comment()

[1P-718]OptoChaperone – A biohybrid tool for regulating protein condensates in cells and in vitro

○Do Thanh Tuan1,2, Motonori Matsusaki3, Soichiro Kawagoe3, Hiroyuki Kumeta4, Tomohide Saio2,3 (1. Department of Physiology, Hanoi Medical University, Hanoi, Vietnam, 2. Graduate School of Medicine, Tokushima University, Tokushima, Tokushima 770-8503, Japan, 3. Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Tokushima 770-8503, Japan, 4. Faculty of Advanced Life Science, Hokkaido University, Sapporo, Hokkaido 001-0021, Japan)
Comment()

[1P-719]Elucidating the molecular basis of translational dysregulation in autism spectrum disorder

○Taisei Asao1, Taichi Shiraishi1, Kazuya Ichihara1, Jun Nomura2, Toru Takumi2, Akinobu Matsumoto1 (1. Division of Biological Science, Graduate School of Science, Nagoya University, 2. Department of Physiology and Cell Biology, Kobe University School of Medicine)
Comment()

[1P-721(1PS-10-09)]Temperature acclimation in C. elegans is regulated by detoxification metabolic pathways in the nervous system

○Moe Tezuka1, Misaki Okahata1, Akane Ohta1, Atsushi Kuhara1,2 (1. Laboratory of Molecular and Cellular Regulation Graduate school of Natural Science Konan University, 2. PRIME, AMED)
Comment()

[1P-722]Functional and structural analysis of the RAC3 p.N92K mutation implicated in neurodevelopmental disorders

○Keisuke Hamada1, Ryota Sugawara 2,3, Hidenori Ito 2, Marcello Scala 4,5, Hiroshi Ueda 3,6, Hidenori Tabata 2, Koh-ichi Nagata 2,7, Kazuhiro Ogata 1,8 (1. Dept. of Biochemistry, Yokohama City Univ. Grad. Sch. Med., 2. Dept. of Molecular Neurobiology, Inst. for Developmental Research, Aichi Dev. Disability Center, 3. United Grad. Sch. of Drug Discovery & Med. Info. Sci., Gifu Univ., 4. Dept. of Neurosciences, Univ. of Genoa, 5. Unit of Medical Genetics, IRCCS Giannina Gaslini Inst., 6. Center for One Medicine Innovative Translational Research (COMIT), Gifu Univ., 7. Dept. of Neurochemistry, Nagoya Univ. Grad. Sch. Med., 8. Grad. Sch., Int. Univ. of Health and Welfare)
Comment()

[1P-723]Critical factors for flow cytometry analysis of the brain

○Tetsushi Sadakata1, Mizuki Sadakata1, Ayumu Konno2, Takatoshi Iijima3, Hirokazu Hirai2 (1. ERSC, Gunma Univ Grad Sch of Med, 2. Dep of Neurophysiol and Neural Repair, Gunma Univ Grad Sch of Med, 3. Dep of Mol Life Sci, Sch of Med, Tokai Univ)
Comment()

[1P-724]Elucidation of the mechanism of parkinsonism caused by decreased function of the glycolytic enzyme Pgk.

○Tomonori Ichioka1, Takashi Kasai2, Fukiko Morii2, Hideki Yoshida1 (1. Kyoto Institute of Technology , 2. Kyoto Prefectural University of Medicine)
Comment()

[1P-725(1PS-03-04)]Single-Cell Transcriptomic Analysis Reveals Aging-Associated Microglial Subpopulations, Their Dynamics, and Disease Relevance

○Hinase Moridono1,2, Ayaka Sugai1,3, Merve Bilgic1, Yukiko Gotoh3, Yusuke Kishi1,3 (1. Institute for Quantitative Bioscience, 2. Faculty of Pharmaceutical Sciences, 3. Graduate school of Pharmaceutical Sciences)
Comment()

[1P-726]The Role of Lysosomal Membrane Integrity and Damage Response in Protein Aggregate Propagation in Neurodegenerative Diseases

○Keita Kakuda1, Kensuke Ikenaka1, Junko Doi1, Chi-jing Choong1, César Aguirre1, Hideki Mochizuki1 (1. The University of Osaka)
Comment()

[1P-727]TDP-43 dysregulation and motor impairment in mice carrying a partial Tardbp 3´UTR deletion

○TRA THI HUONG DINH1, Chigusa Imura1, Mayu Shiokawa1, Shinya Ayabe2, Atsushi Yoshiki2, Haruhisa Inoue3,4,5, Takanori Amano1 (1. Next Generation Human Disease Model Research Team, RIKEN BioResource Research Center, 2. Experimental Animal Division, RIKEN BioResource Research Center, 3. iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center, 4. Center for iPS Cell Research and Application (CiRA), Kyoto University, 5. Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP))
Comment()

[1P-728]Dysregulation in lipid droplet metabolism promotes α-Synuclein aggregation

○Ryota Kasahara1,2, Jun Ogata1, Noriko Ueno4,5, Emi Tokuda4, Naoko Kaga4, Yoshiki Miura4, Yoshimi Miki6, Yuki Nagasaki6, Makoto Murakami6, Eiyu Imai7, Toshihiko Nogawa7, Hisako Akiyama1,8,9, Yoshio Hirabayashi10,11, Nobutaka Hattori1,2,12, Yuzuru Imai1,3 (1. Juntendo Univ. Grad Sch of Med.Dept of Neurol., 2. Juntendo Univ. Grad Sch of Med. Cent for Gen and Regen Med., 3. Juntendo Univ. Grad Sch of Med. Inst for Diseases of Old Age., 4. Juntendo Univ. Grad Sch of Med. Biomed Res Core Facilities.Lab of Proteomics and Biomol Sci., 5. Juntendo Univ. Fac of Pharm. Lab of Pharmaceutical Analytical Chem., 6. Univ Tokyo. Grad Sch of Med. CDBIM.Lab of Microenvironmental and Metab Health Sci., 7. RIKEN. CSRS.Mol Struct Charact Unit., 8. Juntendo Univ. JARIHES., 9. RIKEN. CBS. Lab for Neural Cell Dynamics., 10. Juntendo Univ. Inst for Enviromental and Gender-Specific Medicine., 11. RIKEN. PRI., 12. RIKEN. CBS. Neurodegenerative Disorders Collab Lab.)
Comment()

[1P-729]Identification of characteristic vascular endothelial cell population by a web-based integrative transcriptome analysis of CD146mid/high cells derived from pannus in RA mouse model

○Satoshi Kanazawa1, Yoko Miura1, Nadia Milad1, Shunichi Kosugi2, Hideki Noguchi2 (1. Nagoya City University Graduate School of Medical Sciences, 2. Department of Neurodevelopmental Disorder Genetics, National Institute of Genetics, Center for Genome Informatics)
Comment()

[1P-730]Multi-omics Analysis of Epitranscriptional and Translational Dysregulation During Cerebral Ischemia reveals a role of tRNA modifications.

○Sherif Rashad1, Yuki Kitamura1, Hajime Ikenouchi1, Daisuke Ando1, Hidenori Endo1, Kuniyasu Niizuma1 (1. Tohoku University)
Comment()

[1P-731]Diagnosis of sporadic Creutzfeldt-Jakob disease based on features from resting state electroencephalogram

○Chisho Takeoka1, Tetsushi Yada1, Toshimasa Yamazaki2, Yoshiyuki Kuroiwa3, Kimihiro Fujino3, Toshiaki Hirai3, Hidehiro Mizusawa4 (1. Grad. Sch. of Comp. Sci. Syst. Eng., Kyutech., 2. Office for Career Support, Sch. of Comp. Sci. Syst. Eng., Kyutech., 3. Teikyo Univ. Sch. of Med. Mizonokuchi Hospital, Dept. of Neurol., 4. National Cent. of Neurol. and Psych.)
Comment()

[1P-732]Function of the deSUMOylating enzyme Senp7 in neural development

○Misaki Kato1, Taisuke Moriya1, Kazuhiro Akiyama1, Seiya Yamada1, Shin-ichi Sakakibara1 (1. Waseda University)
Comment()

[1P-734]Analysis of Molecular Mechanisms Underlying Abnormal Lamination of the Cerebral Neocortex in Down Syndrome

○Kanae Ichikawa1, Yasuki Naito1, Yuta Suzuki1, Nobuhiro Kurabayashi2, Kamon Sanada1 (1. The University ofTokyo, 2. Tokyo Metropolitan Institute of Medical Science)
Comment()

[1P-735]The role of the immature choroid plexus in autism spectrum disorder pathology

○Shunta Yamamoto1, Keita Nakano1, Yu Sugimoto1, Takaya Funo1, Tomoyuki Yamaguchi1, Toshifumi Fukuda1 (1. Tokyo University of Pharmacy and Life Science)
Comment()

[1P-737]Possibility of age-related changes in expression of KATP channel component proteins.

○Kobayashi Yuta1, Tanaka Katsuki1, Hosaka Yumi1, Kawada Kouichi1, Uno Kyosuke1, Kuramoto Nobuyuki1 (1. Setsunan Univ.)
Comment()

[1P-738]Cytogenetic Analysis of Male and Female Rett Syndrome Cases with Skewed Mosaic Chromosomal Patterns

○Kenji Orimoto1, yjiro Matsuishi2, Kotaro Yuge3, Shin-ichi Horike4, Makiko Meguro4 (1. Fureai Higashi-Totsuka Hospital・General Medicine, 2. Cognitive and Molecular Research Institute of Brain Diseases, Kurume Univ., 3. Dept of Pediatr, Sch of Med, Kurume Univ., 4. Div of Functional Genomics, Adv Sci Res Ctr, Kanazawa Univ.)
Comment()

[1P-739]Uptake and biological responses to nanoplastic particles in human neural stem cells

○Tomohiro Ito1, Tsunehiko Hongen2, Hideko Sone2, XianYang Qin3, Yudai Ikuno1, Kosuke Tanaka1, Osamu Udagawa1, Fumihiko Maekawa1 (1. National Institute for Environmental Studies, 2. Yokohama Univ. Pharmacy, 3. RIKEN)
Comment()

[1P-740]Cell-to-cell propagation of a-synuclein aggregates by senescence-like astrocytes via lysosomes

○Yurika Honda1, Kota Ohashi1, Naoki Hisamoto1, Kunihiro Mastumoto1, Hiroshi Hanafusa1 (1. Nagoya univ.)
Comment()

[1P-741]In vitro and in vivo analysis of amyloid β dynamics using time-resolved X-ray measurements

○Kotaro Ozaki1, Kazuaki Yoshimune2, Yoichi Sinkai3, Masahiro Kuromochi1,4 (1. Ibaraki Univ., 2. NIhon Univ., 3. AIST, 4. Tokyo Univ.)
Comment()

[1P-742]Circulating viral proteins as risk factors for HIV-associated neurocognitive disorders (HAND)

○Akihiro Matsunaga1, Naokatsu Ando2, Kensuke Komatsu2, Hiroyuki Gatanaga2, Shinichi Oka2, Yukihito Ishizaka1 (1. Japan Institute for Health Security (JIHS), Dept. of Intractable Diseases, 2. JIHS, AIDS Clinical Center)
Comment()

[1P-743]ATP imaging reveals the relationships between ATP concentration and neural activity in a mouse model of schizophrenia

○Ryosuke Ochi1, Hizuki Hamada1, Hideki Miwa2, Masamichi Yamamoto1 (1. National Cerebral and Cardiovascular Center, 2. National Center for Neurology and Psychiatry)
Comment()

[1P-744]Development of a single-cell in situ visualization technique for MTOR mutations to elucidate the pathophysiology of FCD

○Minami Mizuno1, Tomoo Owa1, Xinyang Zhou1, Kazumi Shimaoka1, Satoshi Miyashita1, Mikio Hoshino1 (1. Department of Biochemistry and Cellular Biology, National Institute of Neuroscience)
Comment()

[1P-745]The molecular basis of exercise-induced iron metabolism dysregulation in the brain is a subject of current research.

○Takako Fujii1, Shotatsu Sai2,3,4, Chifang Hsu2,4, Masaki Kaneko2,4, Katsuhiko Hata1,3,5 (1. Department of Sport and Medical Science in Kokushikan University, 2. The Health physical education and sports science of Kokushikan University, 3. Research Center for Mathematical Medicine, 4. Orthomolecular Nutrition Laboratory, 5. Tokyo University of Science)
Comment()

[1P-746]Identification of neuroprotective autoantibodies in aged stroke model

○Ayame Nagafuchi1, Mana Iizuka2, Ako Matsui1, Akihiko Yoshimura2, Minako Ito1 (1. Medical Institute of Bioregulation, Kyushu University, 2. Research Institute for Biomedical Sciences)
Comment()

[1P-747]Leak expression in Cre-dependent DNA constructs assessed in the mouse genome using sensitive bioluminescent reporter

○Toshiaki Nakashiba1, Takashi Sugiyama2, Satoshi Iwano4,3, Atsushi Yoshiki1, Mizuho Iwama1, Atsushi Miyawaki3, Kuniya Abe1 (1. RIKEN BRC, 2. Evident Corporation, 3. RIKEN CBS, 4. University of Miyazaki)
Comment()

[1P-748]In vitro synergy of plant specialized metabolites in suppressing inflammation in RAW264.7 macrophage cells

○Kaori Terashita1, Masato Kohakura1, Katsura Sugawara1, Takuya Uemura1, Shin-ichi Miyagawa1, Gen-ichiro Arimura1 (1. Tokyo university of science)
Comment()

[1P-749]Evaluation of skin of murine psoriasis by analysis of mRNA derived from skin and hair root cells.

○Rinka Ofuji1, Nobuo Nagai1, Hiroaki Yamamoto1, Atsushi Ogura1 (1. Nagahama Institute of Bio-Science and Technology)
Comment()

[1P-751]KN3014 attenuates hepatic ischemia-reperfusion Injury

○Junya Masumoto1,2, Takahiro Hikida2,3, Akimasa Sakamoto3,2, Naoe Kaneko1,2, Mie Kurata1,2, Toshihiro Yamamoto1,2, Natsue Wada1,2, Yukiko Wada1,2, Takanori Nakamura1,2, Yuzo Umeda3 (1. Ehime University Proteo-Science Center, 2. Ehime University Proteo-Science Center and Graduate School of Medicine, Department of Pathology, 3. Ehime University Proteo-Science Center and Graduate School of Medicine, Department of Hepato-Biliary-Pancreatic and Breast Surgery)
Comment()

[1P-752]Murine monocyte-derived macrophages do not express CD163: Comparative analysis using macrophages from representative mammals

○Yoichi Saito1, Yukio Fujiwara2, Yuta Nakashima1,3,4 (1. Lab. Bioengineering, Fac. Advanced Sci. and Tech., Kumamoto Univ., 2. Dept. Cell Pathol., Grad. Sch. Med. Sci., Fac. Life Sci., Kumamoto Univ., 3. Inst. of Industrial Nanomaterials, Kumamoto Univ., 4. FOREST researcher, Japan Sci. and Tech. Agency (JST))
Comment()

[1P-753]The role of uPAR in vascular dysfunction and fibrosis progression

○Yosuke KANNO1, Kao Okumura1, Osamu Matsuo2, Ozaki Kei-ichi1 (1. Doshisha Women’s College of Liberal Arts, 2. Kindai University)
Comment()

[1P-754]DRD2 signaling ameliorates cisplatin-induced kidney injury.

○Takeshi Terabayashi1, Toshiya Nishizawa1, Takako Sasaki1, Yoshihiro Yamanishi2, Toshimasa Ishizaki1 (1. Oita Univ., 2. Nagoya Univ.)
Comment()

[1P-755]Investigation of inhibitory ingredients of IL-18 activation in Ginger Extract and analysis of its action mechanism

○Hiroki Kamino1, Hitoshi Kotani2, Yuko Nariai1, Tomoko Sugiura1, Takeshi Urano1,3 (1. CVTAID, Shimane Univ., 2. Dept. Immunol., Fac. Med., Shimane Univ., 3. mAbProtein Co. Ltd.)
Comment()

[1P-756]Two E-boxes in the Rag1-promoter is essential for the V(D)J recombination of Tcr and Igh genes.

○Reiko Hidaka1, Kazuko Miyazaki1, Hiroshi Kawamoto1, Masaki Miyazaki1 (1. Kyoto University, Institute for Life and Medical Sciences, Department of Immunology.)
Comment()

[1P-757]CCL20 and Its Receptor CCR6 Control IgE Release and Th2 Cell–Related Responses in a Papain-Induced Atopic Dermatitis Model

○Supanuch Ekronarongchai1, Nozomi Sachi1, Salinthip Kengtrong1, Tanadon Pathapech1, Ornjira Tongprasert1, Yomei Kagoshima1, Sotaro Ozaka1, Masaaki Okamoto1, Naganori Kamiyama1, Takashi Kobayashi1 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University)
Comment()

[1P-758]AI-driven TCR binding analysis for drug design in autoimmune diseases

○Kazuki Nakanishi1,2, Hideyuki Shimizu1,2 (1. Department of AI Systems Medicine, M&D Data Science Center, Institute of Integrated Research, Institute of Science Tokyo, 2. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-759]Diabetic Wound Microenvironment Modulation via Stem Cell-Derived Components and Antioxidant Nanoparticles

○Lin Yu Chen1, Chang Ming Min2, Pan Shin Chen3, Nagasaki Yukio 4, Wu Chia Ching2,1 (1. Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 2. Institute of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, 3. National Cheng Kung University Hospital, 4. National Cheng Kung University Nanomedicine Research Center)
Comment()

[1P-760]Kinesin molecular motor KIF11 functions during innate immune responses

○Takeshi Kinoshita1, Daisuke Inoue2, Kosuke Tsuchiya1, Takashi Suda1 (1. Cancer Research Institute, Kanazawa University, 2. Faculty of Design, Kyushu University)
Comment()

[1P-761]Enhanced therapeutic efficacy of designer cells by mitophagy-inducing nanocarriers

○Rinko Aso1, Sogo Aoki1, Kiyoshi Sato1, Hiroyoshi Kawakami1 (1. Applied Chemistry for Environment, Graduate School of Urban Environmental Sciences, Tokyo Metropolitan University)
Comment()

[1P-762]Effects of the CCL20/CCR6 Axis on the Intestinal Localization of RORt+Foxp3+Regulatory T Cells and the Pathogenesis of Colitis

○Nozomi Sachi1, Ekronarongchai Supanuch1, Yomei Kagoshima1,3, Misako Ueno1, Eiko Nakano1, Shimpei Ariki1, Tatsuhito Umeki1,4, Sotaro Ozaka3, Naganori Kamiyama1,2, Takashi Kobayashi1,2 (1. Dpt IDC, Oita Univ., 2. RCGLID, Oita Univ., 3. Dpt GA, Oita Univ., 4. Dpt EMRN, Oita Univ.)
Comment()

[1P-763(1PS-14-06)]Development of Anti-Sepsis Drug Focusing on Vasoprotective Activities of High-Density Lipoprotein

○Reina Nakanishi1, Tatsuya Murakami1,2 (1. Toyama Prefectural Univ., 2. Kyoto Univ.)
Comment()

[1P-764]Development of Liver Disease Model Mice by in vivo multiple base-editing

○Madoka Aoki1, Woojin Kang3, Taito Taki1, Kosuke Okada2, Satoru Takahashi3, Seiya Mizuno3 (1. PhD. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 2. Division of Medical Sciences, Institute of Medicine, University of Tsukuba, 3. Laboratory Animal Resource Center, Transborder Medical Research Center, Institute of Medicine, University of Tsukuba)
Comment()

[1P-765]Investigation of contact hypersensitivity in RET-transgenic mice

○Matsuri Mizoguchi1, Yoshiyuki Kawamoto1, Kozue Takeda1 (1. Chubu University)
Comment()

[1P-766]Emergence of Th1-like Regulatory T Cells (Th1-Tregs) following Plasmodium Infection

○Masaaki Okamoto1, Supanuch Ekronarongchai1, Yomei Kagoshima1, Sotaro Ozaka1, Nozomi Sachi1, Naganori Kamiyama1,2, Takashi Kobayashi1,2 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University, 2. Research Center for GLOBAL and LOCAL Infectious Diseases, Oita University)
Comment()

[1P-767]Functional role of small GTPase Arf1 in innate immune response

○Daiki Iijima1, Mami Sumiyoshi1, Tomoki Ito2, Satoshi Matsuda1 (1. Dept. Cell Signal., Kansai Med Univ., 2. Dept. Int Med. 1., Kansai Med Univ.)
Comment()

[1P-768]Analysis of the Mechanisms Underlying Exacerbation of DSS-induced Colitis in the absence of CCL9-CCR1 signal

○Yomei Kagoshima1,2, Sotaro Ozaka1,2, Yua Kasahara1, Supanuch Ekronarongchai1, Nozomi Sachi1, Sinpei Ariki1,2, Tatsuhito Umeki1, Naganori Kamiyama1,3, Masaaki Okamoto1, Kazuhiro Mizukami2, Takashi Kobayashi1,3 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University, 2. Department of Gastroenterology, Faculty of Medicine, Oita University, 3. Research Center for GLOBAL and LOCAL Infectious Diseases, Oita University)
Comment()

[1P-770(1AS-17-04)]Single Cell and Spatial Transcriptome Profiling of Temporal Artery Biopsies Reveals Molecular Pathology of Giant Cell Arteritis

○Nobumasa Watanabe1, Makoto Sugihara1,2, Yuichiro Hara1,3, Kazunari Sekiyama4, Eisuke Takamasu5, Naofumi Chinen6, Kota Shimada5, Hideya Kawaji1 (1. Tokyo Metropolitan Institute of Medical Science, Research Center for Genome & Medical Sciences, 2. Tokyo Metropolitan Tama-Hokubu Medical Center, 3. Kitasato University School of Frontier Engineering, 4. Tokyo Metropolitan Institute of Medical Science, Center for Medical Research Cooperation, 5. Tokyo Metropolitan Tama Medical Center, 6. Tokyo Metropolitan Tama-Nambu Chiiki Hospital)
Comment()

[1P-771]Screening of traditional Japanese herbal medicines with anti-inflammatory effects using NF-kB reporter assays

○Mao Noda1, Yomei Kagoshima1, Sotaro Ozaka1, Supanuch Ekronarongchai1, Tatsuhito Umeki1, Nozomi Sachi1, Masaaki Okamoto1, Naganori Kamiyama1,2, Takashi Kobayashi1,2 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University, 2. Research Center for GLOBAL and LOCAL Infectious Diseases, Oita University)
Comment()

[1P-772]Lumbar lymph nodes are aberrant in SOD1G93A mice

○Yoshihiro Harada1, Mio Kawazoe1, Ako Matsui1, Minako Ito1 (1. Div. Allergy and Immunology, Medical Institute of Bioregulation, Kyushu Univ.)
Comment()

[1P-773]Effect of the intestinal microbiota regulation by Paneth cell α-defensin on food allergy development

○Kanta Harasawa1, Shuya Ohira1,2, Miu Ihara1, Yuna Abe1, Yokoi Yuki1,2, Kiminori Nakamura1,2 (1. Innate Immunity Lab., Grad. Sch. of Life Sci., Hokkaido Univ., 2. Innate Immunity Lab., Faculty of Adv. Life Sci., Hokkaido Univ.)
Comment()

[1P-774]Overexpression of the cell size controlling factor suppresses lymphocyte oncogenesis induced by Pten deficiency

○Kazumi Kimura1, Keiko Saiki1, Yasuko Yamasaki1, Rika Miyazaki1, Kazuo Yamamoto1 (1. Division of Cell Function Research Support, Biomedical Research Support Center, Nagasaki University School of Medicine)
Comment()

[1P-776]NADase SARM1 contributes to the phenotype of a mouse inflammatory disease model

○Ryoichi Sugisawa1, Akiyoshi Komuro1, Takeshi Ueda1, Naofumi Tomimoto1, Andrew Bowie2, Hitoshi Okada1 (1. Department of Biochemistry, Kindai University Faculty of Medicine, 2. Trinity College Dublin)
Comment()

[1P-777]Analysis of Human Basophil Differentiation Pathways Using Single-Cell RNA Sequencing

○Ami Homma1, Hajime Karasuyama1, Kensuke Miyake1 (1. Insitute of Integrated Research, Institute of Science Tokyo)
Comment()

[1P-778]Comprehensive analysis of DNA repair and gene expression in patient-derived biliary tract carcinoma organoids after ionizing radiation

○Ken Okuda1, Shunji Haruna1, Toshihide Muramatsu2, Kohei Tateno1,3, Mayu Isono1, Kunihiro Miyazaki1, Takahiro Oike4, Haruka Okami5, Takehiko Yokobori5, Keiji Suzuki6, Kensuke Otsuka7, Akiko Takahashi8, Yoshimasa Saito2, Atsushi Shibata1 (1. Division of Molecular Oncological Pharmacy, Faculty of Pharmacy, Keio University, 2. Division of Pharmacotherapeutics, Faculty of Pharmacy, Keio University, 3. Department of General Surgical Science, Graduate School of Medicine, Gunma University, 4. Department of Radiation Oncology, Graduate School of Medicine, Gunma University, 5. Division of Gene Therapy Science, Gunma University, Initiative for Advanced Research (GIAR), 6. Department of Radiation Medical Sciences, Atomic Bomb Disease Institute, Nagasaki University, 7. Biology and Environmental Chemistry Division, Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry, 8. Division of Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research)
Comment()

[1P-779]Skin cytotoxicity and light irradiation effects of perovskite.

○Masafumi Koremura1, Kaoru Yoshida1, Tsutomu Miyasaka1, Masashi Ikegami1 (1. Graduate school of engineering, Toin University of Yokohama)
Comment()

[1P-780]The effect of S-(1, 2-dichlorovinyl)-L-cysteine (DCVC) on the pancreas

○Eri Shiragami1,2, Norikazu Komoriya2, Nobuaki Shirai2, Hiroki Tomisawa2, Kenichi Kobayashi3, Hiromi Hagiwara1, Kaoru Yoshida 1 (1. Department of Biomedical Engineering, Graduate School of Engineering, Toin University of Yokohama, 2. Drug Metabolism Tsukuba Labs, Nemoto Science Co., Ltd., Ibaraki, Japan, 3. Shibukawa Labs., SRD Biology Center Co., Ltd., Gunma, Japan)
Comment()

[1P-781]Immunological Function Analysis of Fibrinogen Using Medaka

○Nako Araki1, Yuki Hayashi1, Yuko Watanabe1, Kiyotaka Hitomi1 (1. Nagoya Univ.)
Comment()

[1P-782]Establishment of an Approach for Tracking and Depleting Regulatory T Cells Lacking Key Transcription Factors and Transcriptomic Analysis

○Naoya Kase1, Hina Nakamura2, Chizuru Nakakomi3, Manami Shimakata2, Mai Banno3, Ryotaro Kanari1, Yohsuke Harada1,2 (1. Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Department of Pharmacoscience, Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 3. Department of Pharmacy, Faculty of Pharmaceutical Sciences, Tokyo University of Science)
Comment()

[1P-783]Inflammasome-mediated exacerbation of Gram-positive bacteria infections

○Hideki Hara1 (1. Asahikawa Medical University)
Comment()

[1P-786]Elucidation of the mechanism which suppressed antiviral responses by aged-specific macrophage

○Hiroyuki Kondo1, Koji Yasutomo1 (1. Tokushima university)
Comment()

[1P-787]PLSCR1 interacts with the SARS-CoV-2 Spike protein through its two regions.

○Shuichi Kusano1 (1. Kagoshima University)
Comment()

[1P-788]Elucidating the role of optineurin in Salmonella infection

○Masaya Fukushi1, Yusuke Sotomaru2, Shintaro Tahara1, Daisuke Oikawa3, Tsuyoshi Miki4, Nobuhiko Okada4, Fuminori Tokunaga3,5, Hideshi Kawakami6, Takemasa Sakaguchi1 (1. Hiroshima Univ., 2. Hiroshima Univ., Natural Science Center for Basic Research and Development, 3. Osaka Metropolitan Univ., 4. Kitasato Univ., 5. Osaka Metropolitan Univ. Research Institute for Drug Discovery Sciences, 6. Hiroshima Univ., Research Institute of Radiation Biology and Medicine)
Comment()

[1P-789(1MS-03-07)]Meta-analysis of RNA modification-related genes in HTLV-1 -infected cells

○Rei Gibu1,2, Kodai Gibu3,4, Yuko Aihara2, Motomi Yamazaki2, Makoto Yamagishi1, Masamitsu Konno2,5,6,7 (1. UTokyo GSFS, 2. AIST CMB, 3. UTokyo GSALS, 4. AIST GSJ, 5. The Univ. of Osaka, 6. YCU, 7. TUS)
Comment()

[1P-790]Identification of novel virulence factors in Toxoplasma gondii

○Naganori Kamiyama1, Eito Tanabe1, Yoshiaki Hayashi1, Mai Ueno1, Nozomi Sachi1, Sotaro Ozaka1, Yomei Kagoshima1, Supanuch Ekronarongchai1, Masaaki Okamoto1, Masahiro Yamamoto2, Takashi Kobayasi1 (1. Oita Univeresity, 2. Osaka University)
Comment()

[1P-791]Development of Biofunctional PVA-Based Film-Forming Liquid Bandages with Antibacterial Efficacy

Ching-Wen Liu1, Ming-Yueh Wang2, ○Li-Ching Chang3,4 (1. Department of Natural Biotechnology, Nanhua University, 2. Department of Athletic Performance, National University of Kaohsiung, 3. School of Medicine, I-Shou University, 4. Department of Pharmacy, E-Da Hospital, I-Shou University)
Comment()

[1P-792]Development of a method for preventing infection in captive axolotls using residual chlorine in tap water.

○Santako Fuzzy-Navel1,2, Yoshichika Yokoe1,3,4, Haruka Axolotl Sugiyama1 (1. HAL lab Axolotl, 2. Axolotl Rescue, 3. SciMoun-tech, 4. The University of Tokyo)
Comment()

[1P-793]Analyzing the Trypsin-Independent Infection Mechanism of Rotavirus

○Sayuri Komatsu1, Tomohiro Kotaki1, Zelin Chen1, Kanako Matsumura1, Katsuhisa Hirai1, Takahiro Kawagishi1,2, Shohei Minami1, Yuta Kanai1, Takeshi Kobayashi1,2,3 (1. Department of Virology, Research Institute for Microbial Diseases, The University of Osaka, 2. Center for Advanced Modalities and DDS, The University of Osaka, 3. Center for Infectious Disease Education and Research, The University of Osaka)
Comment()

[1P-794]Dynamics of Cytokine Storm Progression in Severe Dengue at Organ Level

○Mohamad Al kadi1, Maika Yamashita1, Yusuke Sakai3, Masayuki Shimojima2, Tomoki Yoshikawa2, Noriyo Nagata3, Hideki Ebihara2, Daisuke Okuzaki1, Takeshi Kurosu2 (1. Human Immunol. (SCG), WPI-IFReC, OU Univ., 2. Dept. of Virology I, NIID, 3. Dept. of Pathology, NIID)
Comment()

[1P-795]Universal and quantitative detection of viral double-stranded RNA using a luciferase-based biosensor

○Michihito Sasaki1,2, Eri Fujii1, Satoko Sasaki1, Takuma Ariizumi1, Kei Konishi1,3, Akihiko Sato1,2,3, Hirofumi Sawa1,2, Yasuko Orba1,2 (1. IIZC, Hokkaido University, 2. IVReD, Hokkaido University, 3. Shionogi & Co., Ltd.)
Comment()

[1P-796]Generation of recombinant bovine coronavirus requires co-expression of the spike protein and hemagglutinin-esterase

○Yoshio Sugiura1, Tatsuki Takahashi1, Kenta Shimizu1, Sodbayasgalan Amarbayasgalan1, Enkhjin Dorjsuren1, Shunji Yasuki1, Like Luo1, Wataru Kamitani1 (1. Department of Infectious Diseases and Host Defense, Graduate School of Medicine, Gunma University)
Comment()

[1P-797]Establishment of a red river hog-derived macrophage cell line and its susceptibility to African swine fever virus

○Rina Ikeda1,2, Kentaro Masujin1, Takato Takenouchi2,3, Seiki Haraguchi3, Shunichi Suzuki3, Hirohide Uenishi3, Eiji Onda4, Takehiro Kokuho1 (1. National Institute of Animal Health, National Agriculture and Food Research Organization, 2. University of Tsukuba, Graduate School of Science and Technology, 3. Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 4. Yokohama Zoological Gardens, ZOORASIA)
Comment()

[1P-798]Development of anti-influenza drugs based on host-directed antisense oligonucleotides

○Makoto Shimooka1, Tomomi Kirino1, Harumi Yamaguma2, Natsumi Kameoka2, Hina Miyazaki1, Itsuki Anzai1, Shintaro Shichinohe1, Satoshi Obika3,4,5,6, Yuuya Kasahara2,5, Tokiko Watanabe1,3,4 (1. Department of Molecular Virology, Research Institute for Microbial Diseases, The University of Osaka, 2. National Institutes of Biomedical Innovation, Health and Nutrition, 3. Center for Infectious Disease Education and Research, The University of Osaka, 4. Center for Advanced Modalities and DDS, The University of Osaka, 5. Graduate School of Pharmaceutical Sciences, The University of Osaka, 6. Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka)
Comment()

[1P-799]DNA Gyrase: The Molecular Interface Linking Quinolone and Phage Susceptibility

○Nana Kimura1, Jumpei Fujiki1, Haruka Yamamoto1, Hidetomo Iwano1 (1. Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, School of Veterinary Medicine, Rakuno Gakune University)
Comment()

[1P-800]Favipiravir as an antiviral drug candidate against Oropouche virus infection

○Cassia Sousa Moraes1,2, Atsuko Inoue1,3, Koshiro Tabata1, Akihito Sato4,5, Joshua Kranrod1,6, Keita Matsuno7,8, Shinji Saito1, Gabriel Gonzalez9, Hirofumi Sawa1,8, Yukari Itakura1 (1. Division of Biological Response Analysis, Institute for Vaccine Research and Development, Hokkaido University., 2. Graduate School of Infectious Diseases, Hokkaido University, Japan., 3. Faculty of Pharmaceutical Science, Graduate School of Life Science, Hokkaido University, Japan., 4. Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University., 5. Laboratory for Drug Discovery & Disease Research, Shionogi & Co., Ltd., 6. Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University., 7. Division of Risk Analysis and Management, International Institute for Zoonosis Control, Hokkaido University., 8. One Health Research Center, Hokkaido University, Sapporo, Japan., 9. Division of Research Support, Institute for Vaccine Research and Development, Hokkaido University.)
Comment()

[1P-801]Development of the preparation method for hepatocytes of hepatitis B virus - like particles for drug and gene delivery.

○Yuta Miyazumi1, Eri Takayama1, Akito Kawase1, Misaki Enomoto1, Madoka Ogawa1, Yuki Iwaisako1, Masahiro Fujimuro1 (1. Kyoto pharmaceutical university)
Comment()

[1P-802]Analysis of Phagocytic Response of Macrophage Cell Lines to Phage-Resistant Pseudomonas aeruginosa

○Manaho Shimizu1, Jumpei Fujiki1, Yusaku Watanabe1, Hidetomo Iwano1 (1. Rakuno Gakuen University Faculty of Veterinary Medicine Veterinary Biochemistry Unit)
Comment()

[1P-803]Fitness Analysis of Phage-Induced Virulence Changes in Escherichia coli ST131

○Haruka Yamamoto1, Fujiki Jumpei1, Nana Kimura1, Toyotaka Sato2, Hidetomo Iwano1 (1. rakuno gakuen university veterinary biochemistry unit, 2. Laboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University)
Comment()

[1P-804]Isolation of antigen-specific antibody using yeast displaying human-derived single-chain variable fragments

Kazuhisa Aoki1, Rikio Yabe1, Sayaka Ono1, Mayumi Saeki1, Yuri Tanno1, ○Hidetaka Tanno1,2 (1. Tokyo Metropolitan Institute of Medical Science, 2. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Comment()

[1P-805]Skin aging driven by inter-tissue network changes with age

○Haruki Horiguchi1, Yuichi Oike1 (1. Kumamoto Univ.)
Comment()

[1P-807]Therapeutic Potential of Restoring Cochlear Gap Junction Plaques as a Target for Age-Related Hearing Loss

○Takao Ukaji1,2, Kazusaku Kamiya2 (1. Sch. of Pha., Nihon Univ., 2. Dept. of Oto., Sch. of Med., Juntendo Univ.)
Comment()

[1P-808]Comprehensive analysis of testicular gene expression associated with testicular microlithiasis in Japanese Black bulls

○Masashi Kinukawa1, Susumu Haruta1, Yousuke Naniwa1, Nagisa Kato1, Kazuhito Kurogi1, Keishi Mizutani1, Masanori Koyago1, Kyoko Uchiyama1 (1. LIVESTOCK IMPROVEMENT ASSOCIATION OF JAPAN, INC)
Comment()

[1P-809(1PS-18-05)]Hormonally regulated network reveals molecular mechanisms of postmenopausal osteoarthritis

○Hirotaka Iijima1, Ambrosio Fabrisia1 (1. Harvard Medical School)
Comment()

[1P-810]The role of cellular senescence in a progeroid mouse model

○Kaho Fujii1, Dai Sakamoto1, Nozomi Hori1, Hideka Miyagawa1, Masahiro Wakita1, Eiji Hara1 (1. Department of Molecular Biology, Research Institute for Microbial Diseases, The University of Osaka)
Comment()

[1P-811]Investigation of the resistance to oxidative stress conferred by S-adenosyl-L-homocysteine in Saccharomyces cerevisiae and Caenorhabditis elegans

○Miyuko Kanaji1, Takafumi Ogawa1, Koji Masumura1, Masaki Mizunuma1 (1. Hiroshima Univ.)
Comment()

[1P-812]Mechanism of lifespan extension by S-adenosyl-L-homocysteine in budding yeast

○Miku Yoshida1, Koji Masumura1, Takafumi Ogawa1, Masaki Mizunuma1 (1. Hiroshima Univ.)
Comment()

[1P-813]Establishment of a model of TNF-α-induced muscle weakness using skeletal muscle organoids

○Yukinori Tamura1, Junpei Ishizaka1, Sho Yokoyama2, Ayune Ochi1, Kota Kishishita2, Ryo Nakajima2, Maho Sakai3, Airi Okugawa4, Toshia Fujisato5, Ken-ichi Mizutani4, Tomohiro Nakamura3 (1. Div. of Physiol & Biochem., Faculty of Nutr., Kobe Gakuin Univ., 2. Dept. of Mech. Eng., Faculty of Eng., Osaka Inst., of Tec., 3. Div. of Human Sci., Faculty of Eng., Osaka Inst. of Tec., 4. Lab. of Stem Cell Biol., Grad. Sch. of Pharm. Sci., Kobe Gakuin Univ., 5. Grad., Course in Appl. Chem., Environ. & Biochem. Eng., Osaka Inst. of Tec.)
Comment()

[1P-814]FMO3 Deficiency Plays a Role in Aging Regulation under Calorie Restriction

○Tatsunobu Nakagawa1, Jinyun Wang1, Issa Furihata1, Toshimitsu Komatsu2, Seongjoon Park3, Isao Shimokawa4, Takuya Chiba1 (1. Biomedical Gerontology Laboratory, School of Human Sciences,Waseda University, 2. Biomedical Research Support Center, School of Medicine, Nagasaki University, 3. Department of Pathology, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 4. Grad. Sch. Biomed. Sci., Nagasaki Univ.)
Comment()

[1P-815]Deficiency of CCN3, a senescence marker of cartilage, attenuates osteoarthritis progression in a mouse model of meniscus destabilization-induced osteoarthritis

○Takako Hattori1, Janvier Habumugisha 1,3, Ryuichiro Okuda1,2, Miho Kuwahara1, Kazuki Hirose2, Hiroshi Kamioka3, Satoshi Kubota1 (1. Dept. Biochem. Mol. Dent., Okayama Univ.,Grad. Sch. Med. Dent. Pharm.Sci., 2. Dept. Orthop. Surg., Okayama Univ.,Grad. Sch. Med. Dent. Pharm.Sci., 3. Dept. Orthodontics., Okayama Univ.,Grad. Sch. Med. Dent. Pharm.Sci.)
Comment()

[1P-816]Single-cell resolution of alternative polyadenylation in aging neurons: uncovering a novel regulatory layer in brain function and cognitive decline

○Merve Bilgic1,2, Yusuke Kishi1,2 (1. University of Tokyo, 2. Institute for Quantitative Biosciences)
Comment()

[1P-817]Chronic Helicobacter pylori infection promotes amyloid-beta phagocytosis by OMV-induced microglial activation

○Ah-Mee Park1,2, Fumitaka Sato2, COng Thanh Nguyen2, Ijaz Ahmad2, Seiichi Omura2, Reona Shiro3, Ikuo Tsunoda2 (1. Kindai Univ. Arts & Sci., 2. Kindai Univ. Microbiol., 3. Kindai Univ. ObGyn)
Comment()

[1P-818]The Role of Senescent Cells and Nuclear Receptors in Lung Regeneration in Emphysema

○Mikako Hirose1, Masataka Sugimoto1 (1. National Center for Geriatrics and Gerontology)
Comment()

[1P-819]Comprehensive multiomics analysis reveals distinct differences between different choroid plexus tumors

○ZHENHUA LI1,2, Xuede Zhang2 (1. ShanghaiTech University/Shanghai Clinical Research and Trial Center, 2. The First Affiliated Hospital of Shandong Second Medical University)
Comment()

[1P-820]Impact of FXR Overexpression in Glioblastoma on Macrophage Polarization and Function

○Yao-sheng Wu1, Ying Chen1 (1. National Defense Medical University)
Comment()

[1P-821]CaV3.3 T-type calcium channels contribute to carboplatin resistance in retinoblastoma

○JEONG HUN KIM1,2 (1. Seoul National University College of Medicine, 2. Seoul National University Hospital)
Comment()

[1P-822]Investigation of metastatic properties in 3D-cultured breast cancer cell lines

○Miku Kojima1, Kidai Saijyo2, Taro Tachibana1,2, Chikako Yokoyama1,2 (1. Sch. of Eng., Osaka Met. Univ., 2. Grad. Sch. of Eng., Osaka Met. Univ.)
Comment()

[1P-823]Efficient Intracellular Delivery of PROTAC via Nanoparticle Formation

○Maho Miyamoto1,2, Hidetomo Yokoo2, Kosuke Saito2, Yosuke Demizu1,2 (1. Grad. Sci., Yokohama City Univ., 2. NIHS)
Comment()

[1P-824]Natural Polyphenols Modulate Ferroptosis Mechanisms in Endometrial and Breast Cancer Cell Lines

○Merve Nur Şahan Seçer1, Mine Dosay Akbulut1 (1. Afyon Kocatepe University)
Comment()

[1P-825]Analysis of Gene Regulatory Network in Breast Cancer Dormancy

○Eilma Akter-Yasuoka1, Otoha Horiguchi1, Ryoichi Nishida1, Yusuke Yamamoto2, Shigeki Higashiyama1, Jun Nakayama1,2 (1. Dept. of Oncogenesis Growth Regulation, Res. Inst., Osaka Intl. Cancer Inst., 2. Lab. On Integr. Oncol., Natl. Cancer Ctr. Res. Inst.)
Comment()

[1P-826]Establishment and evaluation of the high-through put screening method for dormancy-induction drugs

○Otoha Horiguchi1, Eilma Akter-Yasuoka1, Yusuke Yamamoto2, Shigeki Higashiyama1, Jun Nakayama1,2 (1. Osaka International Cancer Institute, 2. National Cancer Center Research Institute)
Comment()

[1P-827]Mismatch Repair Dependent Responses to DNA Replication Stress

○Naoki Akiba1,2, Yusuke Matsuno2, Ken-ichi Yoshioka2 (1. Tokyo University of Science, 2. National Cancer Center)
Comment()

[1P-828]The role of serine phosphorylation of annexin A2 in the proliferation of malignant melanoma cells and AKT activation.

○Yuichi Mazaki1, Takahiro Horinouchi2, Yasuhito Onodera3, Jin-Min Nam4 (1. Dept. Cell. Pharm., Grad. Sch. Med., Hokkaido Univ., 2. Dept. Pharm. Sci., Sch. Pharm at Narita, IUHW, 3. Glb. Ctr. Biomed. Sci. Eng., Fac. Med., Hokkaido Univ., 4. Div. Systemic Life Sci., Grad. Sch. Biostudies, Kyoto Univ.)
Comment()

[1P-829]Oral microenvironment influences progression of head and neck squamous cell carcinoma

○YURIKA NAKAJIMA1,2, SYOGO OKAZAKI1, SHUICHI SATO2, KENICHI IMAI1 (1. Dept. of Microbiol. and Immnol., Sch. of Dent., Nihon Univ, 2. Dept. of Periodontology., Sch. of Dent., Nihon Univ)
Comment()

[1P-831]CENP-E inhibition induces innate immune activation through endoplasmic reticulum stress in cancer cells.

○Kumi Kinoshita1,2, Ryo Kamata1, Hitoshi Saito1, Yumi Hakozaki1, Gaku Yamamoto1, Pinyi Lu3, Akihiro Ohashi1,2 (1. National Cancer Center, 2. Univ.Tokyo, 3. FNL)
Comment()

[1P-832]Knockdown of Vault RNA 1-1 Suppresses Cell Proliferation in THP-1 Cells

○Yuki Hatayama1, Hisashi Shimohiro2, Koji Kawamura1 (1. Tottori University Hospital, 2. Tottori University Faculty of Medicine)
Comment()

[1P-833]The Hippo pathway effector YAP promotes metastasis and ferroptosis sensitivity in breast cancer

○Paweenapon Chunthaboon1, Toshiro Moroishi2 (1. Kumamoto University , 2. Institute of Science Tokyo)
Comment()

[1P-834]Ahed, a spliceosomal protein, has crucial roles in proliferation of skin tumor cells

○Mikiro Takaishi1, Kozo Nakai1, Shigetoshi Sano1 (1. Kochi University)
Comment()

[1P-835]Prevotella intermedia Promotes 5-FU Resistance and Therapy-Induced Senescence in Colorectal Cancer Cells

○Jenn-Wei Chen1, Chun-Hung Liu1, Po-Chuan Chen2, Chih-Pin Chuu3, I-Hsiu Huang4 (1. Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Taiwan, 2. Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Taiwan, 3. Institute of Cellular and System Medicine, National Health Research Institutes, Taiwan, 4. Department of Biochemistry and Microbiology, Oklahoma State University Center for Health Sciences, USA)
Comment()

[1P-836]Analysis of transcription factor HIF-1α induction under hypoxia

○Haruto Okada1, Masahiko Oshige1,2,3, Shinji Katsura1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Grad. Sch. of Food & Pop. Health Sci., Gunma Univ., 3. GUCFW)
Comment()

[1P-837]The impact of METTL27 gene expression in human cancers

○Toshifumi Hara1, Tomoharu Takeuchi1 (1. Aichi Gakuin University)
Comment()

[1P-838]Analysis of characteristic gene expression profiles in Drug-Tolerant Persister cells

○Natsumi Aruga1, Teppei Nishino2, Masato Masuda1, Ryouu Takahashi3, Takafumi Miyamoto2 (1. Toyo University, 2. University of Tsukuba, 3. Hiroshima University)
Comment()

[1P-839]MANF knockdown inhibits glioblastoma progression and sensitizes cells to temozolomide

○TZU MIN CHEN1, Ying Chen1 (1. National Defense Medical University)
Comment()

[1P-840]SBI115 inhibits cell cycle, migration and invasion through cAMP/p-CREB downregulation in human bladder cancer

○NI WEI1, YING CHEN1, Yi-Hsuan Lin1, Chien-Chang Kao2 (1. National Defense Medical Center, 2. Tri-Service General Hospital)
Comment()

[1P-841]Small cell lung cancer actively transports ATP to the extracellular space

○Takeshi Tsuruda1, Manabu Kodama1, Keiichi Nakayama1 (1. Lab. Anticancer Strategies, Inst. Integrative Res., Inst. Sci. Tokyo)
Comment()

[1P-842]Exploratory study on SQAP mechanism through co-treatment with HIF-1α degradation Inhibitors

○Mizuno Takamatsu1, Airi Hori2, Hono Kurihara2, Shunya Tanaka2, Masahiko Oshige1,2,3, Shinji Katsura1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Grad. Sch. of Food & Pop. Health Sci., Gunma Univ., 3. GUCFW)
Comment()

[1P-843]Effects of SQAP (Sulfoquinovosyl-acyl propanediol) on angiogenesis

○Suzuka Higeta1, Kentaro Tamiya2, Masahiko Oshige1,2,3, Shinji Katsura1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Grad. Sch. of Food & Pop. Health Sci., Gunma Univ., 3. GUCFW)
Comment()

[1P-844]Analyses of Metabolic Reprogramming in Cancer Cells

○Mei カキウチ Kakiuchi1, Yurina Goto1, Takuma Shiraki1 (1. Kindai University)
Comment()

[1P-845]Suppression effect of taurine on radiation-induced intestinal tumors

○Kazumi Yamauchi1, Yuki Tsutsumi2, Jun-ichiro Komura1, Toshiyuki Kobayashi1 (1. Institute for Environmental Sciences, 2. TESSCO)
Comment()

[1P-846]15dPGJ2 enhances cisplatin cytotoxicity via mitochondrial ROS-mediated cell death in human bladder cancer

○Chien Rui Lai1, Ying Chen1, Tzu-Min Chen1, Sheng-Tang Wu3, Chien-Chang Kao2 (1. national defense medical univesity, 2. Tri-service general hospital, 3. Kaohsiung Armed Forces General Hospital)
Comment()

[1P-847]Mechanisms of cell death induction by targeting ROS in the novel cluster compound Ag5

Ryo Kamata1, ○Yui Takahashi1,2, Gaku Yamamoto1, Ross Breckenridge3, Martin Treder3, Ohashi Akihiro1,2 (1. Exploratory Oncology Research & Clinical Trial Center, National Cancer Center Japan, Kashiwa, Japan, 2. Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan, 3. Arjuna Therapeutics, Milladoiro, Spain)
Comment()

[1P-848]Effect of combination of Glyoxalase I inhibitor and xCT inhibitor on survival and proliferation of cancer cells

○Rintaro Terai1, Ayaka Tanabe1, Risa Shirakawa1, Ryoko Takasawa1 (1. Tokyo University of Science)
Comment()

[1P-849]The Involvement of Glyoxalase I and Nrf2 in Cancer Cell Growth and Metastasis

○Aoi Hamada1, Miaya Oyama1, Wakuru Suzuki1, Ryoko Takasawa1 (1. Facul. Pharm. Sci., Tokyo Univ. Sci.)
Comment()

[1P-850]Effect of tropolone derivatives on quantitative changes of IAP family proteins

○Ruka Ito1, Minori Kimura, Yuria Kuwana, Ryoko Takasawa1 (1. Facul. Pharm. Sci., Tokyo Univ. Sci.)
Comment()

[1P-851]Effect of Glyoxalase I inhibition on apoptosis induced by the anticancer drug doxorubicin

○Haruka Mori1, Manami Sugita1, Ryoko Takasawa1 (1. Facul. Pharm. Sci., Tokyo Univ. Sci.)
Comment()

[1P-852]Epigenetic Silencing of SLC46A3 Confers T-DM1 Resistance in Gastric Cancer Cells

○Rika Matsuo1, Toshimitsu Yamaoka1, Fumihiro Ishikawa2, Yuki Hasebe1, Junji Turutani1 (1. ACT, Showa Med. Univ., 2. Biotec, Showa Med. Univ.)
Comment()

[1P-853(1AS-16-04)]The interaction between pericytes and brain metastases in the in vitro co-culture system

○Shoko Noda-Narita1, Atsu Aiba1 (1. The University of Tokyo)
Comment()

[1P-854]Proximity interactome analysis of cetuximab-induced EGFR using AirID

○Hinako Fujisaki1, Kohdai Yamada1, Hidetaka Kosako2, Tatsuya Sawasaki1 (1. Proteo-Science Center, Ehime University, 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
Comment()

[1P-855]PAK1-dependent regulation of CYP3A4 controls anti-cancer drug resistance in hepatocellular carcinoma cells

○Chao Gao1,2, Lei Wang1,2, Jian Ping Gong2,3, Shinya Tanaka1,2, Masamichi Imajo2 (1. Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, 060-8638, Japan, 2. Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21 W10, Kita-Ku, Sapporo, 001-0021, Japan, 3. Faculty of Advanced Life Science, Hokkaido University, N21 W11, Kita-ku, Sapporo 001-0021, Japan)
Comment()

[1P-856]DUSP22 Suppresses Lung Tumorigenesis by Inhibiting EGFR/c-Met Signaling

○Yu-Ting Liao1, Wen-Jye Lin1 (1. Immunology Research Center, National Health Research Institutes, Taiwan)
Comment()

[1P-857]Establishment and functional analysis of glioma phagocytic microglia

○Norika Doi1, Eisyu Hirata1 (1. Kanazawa University)
Comment()

[1P-858]The HECTD4-ubiquitinated proteins identified with proteomic analysis in prostate cancer cells

○Yasuo Takashima1, Masami Tanaka1, Kengo Yoshii2, Kei Tashiro1 (1. Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, 2. Department of Mathematics and Statistics in Medical Sciences, Kyoto Prefectural University of Medicine)
Comment()

[1P-859]Sublethal cell damage induced by cytotoxic T cells causes phenotypic changes in melanoma

○Momo Mataki1, Yukie Ando1, Sara Hatazawa1, Riko Kumatabara1, Mio Nakajima1, Rikuto Sone1, Akihiro Nakamura1, Mieko Tokano1, Tomonaga Ichikawa1, Takashi Murakami1, Yutaka Horiuchi1 (1. Dept. Microbiol., Saitama Med. Univ)
Comment()

[1P-860]NCYM promotes cholangiocarcinogenesis via activating of autophagy

○Daisuke Muto Muto1,2,5, Kazuma Nakatani1,2, Hiriyuki Kogashi1,2, Zulfin Ummi1,2, Akiko Endo2, Harumi Saida2, Akane Sada2, Kazuto Kugo4, Yoshinori Hasegawa4, Yoshitaka Hippo2,1,3, Yusuke Suenaga2 (1. Grad. Sch. of Med. & Pharm. Sci., Chiba Univ., 2. Evolutionary Oncology, CCCRI, 3. Lab. of Precision Tumor Model Systems, CCCRI, 4. Dept. of Applied Genomics, Kazusa DNA Res. Inst., 5. QST, iQLS)
Comment()

[1P-861]Genetic analysis of tumor progression by multinucleated polyploid giant cells

○Tomoya Ueda1, Masato Enomoto1,2, Tatsushi Igaki1 (1. Kyoto University, 2. University of Fukui)
Comment()

[1P-862]Salinomycin prevents radiation-induced epithelial-mesenchymal transition

○Ryo Saga1, Kenta Iwamori1, Yoichiro Hosokawa2 (1. Hirosaki University, 2. Hirosaki University of Health and Welfare)
Comment()

[1P-863]Fisetin inhibits periodontal pathogen-induced EMT in oral squamous cell carcinoma via the Wnt/β-catenin pathway

○Ruoyao Zhang1, Hiroki Takigawa1, Hugo Maruyama1, Takayuki Nambu1, Chiho Mashimo1, Toshinori Okinaga1 (1. Dept Microbio,Osaka Dental Univ.)
Comment()

[1P-864]Splicing regulatory protein CWC22 prevents mitotic slippage

○Ryuzaburo Yuki1, Youhei Saito1, Yuji Nakayama1 (1. Kyoto Pharmaceutical University)
Comment()

[1P-865]Elucidating the LLPS-mediated interaction mechanism of YAP/TAZ-RBM39 for the development of cancer therapies

○Yukina Kobayashi1, Chiho Watanabe1, Nanako Kataoka1, Mikihito Kajiya1, Toshinori Ando1 (1. Hiroshima University)
Comment()

[1P-866]Effect of progesterone and altrenogest on neuroblastoma cells

○Akifumi Kanda1, Hiyama Eiso1, Sakatani Shigeko1, Sotomaru Yusuke1 (1. Hiroshima Univ. N-BARD)
Comment()

[1P-867]Cancer progression driven by the collapse of macrophage-mediated tumor cell elimination

○Yasuto Fukada1,2, Zhikai He1,3, Deng Sheng1,4, Tatsushi Igaki3, Shigeharu Fujieda2, Masato Enomoto1 (1. Laboratory of Dynamic Biology, Department of Integrative Vascular Biology, Faculty of Medical Sciences, University of Fukui, 2. Department of Otorhinolaryngology Head & Neck Surgery, Faculty of Medical Sciences, University of Fukui, 3. Laboratory of Genetics, Graduate School of Biostudies, Kyoto University, 4. Department of Molecular Oncology, Graduate School of Medicine, Kyoto University)
Comment()

[1P-868]Development of innovative therapeutic technology for drug resistant cancer by nuclear-targeting DDS

○Soma Kawashima Kawashima1, Koji Nagahama2 (1. Graduate school of Konan University ・FIRST, 2. Konan University ・FIRST)
Comment()

[1P-869]Therapeutic potential of adaptor proteins SKAP-1,2 regulating inflammation-associated carcinogenesis

○Kurara Takagane1, Go Itoh1, Sei Kuriyama1, Masamitsu Tanaka1 (1. Akita Univ.)
Comment()

[1P-870]Distribution analysis of ARV-825, an anti-lung fibrosis drug, by MS imaging

○Yumi Unno1, Thi Kim Dung DOAN2, Sabina Quader2, Shigeto Fukushima2, Takushi Yamamoto1, Hiroaki Kinoh2, Kazunori Kataoka2 (1. SHIMADZU, 2. Innovation Center of Nanomedicine (iCONM))
Comment()

[1P-871]Upregulation of LINC02154 contributes to esophageal cancer progression by enhancing cell cycle and epithelial-mesenchymal transition

○Takeshi Niinuma1, Kotoha Shimote1, Kazuya Ishiguro1, Hiroshi Kitajima1, Masahiro Kai1, Hiroshi Nakase2, Hiromu Suzuki1 (1. Dev. Mol. Biol., Dept. Biochem., Sapporo Med. Univ., 2. Dev. Intern. Med., Dept. Gastroentrol. Hepatol., Sapporo Med. Univ.)
Comment()

[1P-872]Development of an Image Data Management System to Support the Integration of Computational and Experimental Biology

○Yusuke Azuma1, Jen-Chien Chang1, Shuichi Onami1,2 (1. RIKEN-TRIP, 2. RIKEN BDR)
Comment()

[1P-873]DOT1L inhibition reprograms innate immunity signaling to potentiate immunomodulatory drug responses in multiple myeloma

○Kazuya Ishiguro1,2, Hiroshi Kitajima1, Takeshi Niinuma1, Reo Maruyama3, Tomohide Tsukahara4, Yoshihiko Hirohashi4, Kohei Kumegawa5, Masahiro Kai1, Hiroshi Nakase2, Hiromu Suzuki1 (1. Div. Mol. Biol., Dept. Biochem., Sapporo Med. Univ., Sch. Med., 2. Div. Gastroenterol. Hepatol., Dept. Int. Med., Sapporo Med. Univ., Sch. Med., 3. Dept. Cancer Epigenome, Cancer Inst., Japanese Found. Cancer, 4. Div. 1st Pathol., Dept. Pathol., Sapporo Med. Univ., Sch. Med., 5. Next-Ganken program, Cancer Inst., Japanese Found. Cancer)
Comment()

[1P-874]Construction and evaluation of a three-dimensional spheroid culture method for cancer cells using synthetic smectite

○Honoka Kitamura1, Yoshihiro Hirade1, Yamada Manami1, Munehiro Kubota2, Takao Omura2, Susumu Shinoki2, Satoshi Tamaki2, Kazutake Tsujikawa1 (1. Osaka University, 2. Kunimine Industries)
Comment()

[1P-875]Exploring the Relationship Between p16Ink4a-Expressing Cells and Systemic Changes in Cancer-Associated Cachexia

○BORUI LI1, Yasuhiro Nakano1,2, Hiroshi Inoue3, Yoshikazu Johmura1,2 (1. Div. Cancer Senescence Biol., Cancer Res. Inst., Kanazawa Univ., 2. Integrated Systems of Aging Res., Inst. Frontier Sci. Initiative, Kanazawa Univ., 3. Metab. Nut. Res., Inst. Frontier Sci. Initiative, Kanazawa Univ.)
Comment()

[1P-876]Omics analysis identifies underlying factors defining cholangiocarcinoma stem cells

○Takafumi Minato1, Osamu Sugahara1, Tsunaki Higa1, Keiichi Nakayama1 (1. Anticancer Strategies Laboratory Advanced Research Initiative Institute of Science Tokyo)
Comment()

[1P-877]Development of novel anticancer agent targeting nucleolar stress pathway

○Tomohiko Maehama1,2, Yoshimi Shimizu1, Miki Nishio2, Junji Otani2, Akira Suzuki1,2 (1. Showa Medical University School of Medicine, 2. Kobe University Graduate School of Medicine)
Comment()

[1P-878]Antimetastatic effect of IL-18 and chemokines

○Naoko Yamada1 (1. Dept. of Surg. Patho., Hyogo Medical Univ.)
Comment()

[1P-879(1AS-13-06)]Identification of human serum proteins related to incidence and survival time of pancreatic cancer using exploratory proteomics

○Yuji Iwashita1, Yuriko Koyanagi1, Yumiko Kasugai1, Isao Oze2, Issei Imoto3, Hidemi Ito2, Keitaro Matsuo1 (1. Div. Cancer Epidemiol. Prev., Aichi Cancer Ctr. Res. Inst., 2. Div. Cancer Ctrl. Info., Aichi Cancer Ctr. Res. Inst., 3. Aichi Cancer Ctr. Res. Inst.)
Comment()

[1P-880]The effect of dead-cell induced by anti-tumor drug on intraperitoneal immunity

○Sakura Arikawa1, Shun Tamaki1, Rei Kawashima1, Tatsunori Maekawa1, Takafumi Ichikawa1 (1. Department of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences)
Comment()

[1P-881]Sex differences in inflammatory colorectal cancer pathogenesis mediated by interleukin-33

○Miho Akimoto1, Takao Susa1, Noriyuki Okudaira1, Harumi Hisaki1, Masayoshi Iizuka2, Mimi Tamamori-Adachi1 (1. Teikyo University , 2. Med. Educ. Ctr., Teikyo Univ. Sch. of Med.)
Comment()

[1P-882]Analysis of liposome-antibody interactions using a flow cytometer

○Tetsuya Okuda1, Michiyo Maruyama1 (1. MolBis, AIST)
Comment()

[1P-883]Cost-Effectiveness of an Olfactory-Based Cancer Risk Screening in Japan: A Decision-Analytic Model

○Aya Hasan Alshammari1, Sura Abbas Khdair2, Masayo Morishita1, Takaaki Hirotsu1, Hideyuki Hatakeyama1, Eric di Luccio1 (1. Hirotsu Bio Science Inc, 2. Al-Mustansiriya Medical University)
Comment()

[1P-884]In vivo evaluation of human amnion-derived mesenchymal stem cell carriers for targeted cancer gene delivery

○Yoshiyuki Yamazaki1, Yuko Nitahara-Kasahara2, Kai Miyazaki3, Yoshitaka Miyagawa1, Takashi Okada2 (1. Nippon Med. Sch., 2. Div. of Mol. and Med. Genet., Inst. of Med. Sci., Univ. of Tokyo, 3. Dept. of Integr. Diagn. Pathol., Nippon Med. Sch.)
Comment()

[1P-885(1MS-03-04)]Disrupting Pancreatic Cancer Metabolism Through Chemically Modified-Glutamine-Mediated Glutamine Antagonism

○Bo Xu1, Chisato Iwabuchi1, Manami Hasegawa2, Honoka Imagawa2, Miyuki Nishida1, Tsuyoshi Osawa1,2,3 (1. Division of Integrative Nutriomics and Oncolygy, RCAST, the University of Tokyo, 2. Department of Chemistry and Biotechnology, Faculty of Engineering, the University of Tokyo, 3. Department of Biological Sciences, Graduate School of Science, the University of Tokyo)
Comment()

[1P-886]Induction of apoptosis in multidrug-resistant colon cancer stem cells via STAT3 and survivin downregulation mechanisms: therapeutic target by skullcapflavone from Andrographis paniculata

○Glenn Oyong1, Maria Carmen Tan2 (1. Department of Physics, De La Salle University, 2401 Taft Avenue, Manila 0922, Philippines, 2. Department of Chemistry, De La Salle University, 2401 Taft Avenue, Manila 0922, Philippines)
Comment()

[1P-887]Spatial Transcriptomic Analysis to Reveal Microenvironmental Heterogeneity in Uterine Carcinosarcoma.

○Takeru Ochi1, Daisuke Yoshimoto2, Yuho Tani1, Haruka Tamura1, Ayumi Taguchi2, Hiroko Matsunaga3, Kenbun Sone2, Haruko Takeyama1,3,4 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. Obs. and Gyn., Tokyo Univ., 3. Res. Org. Nano Life Innov., Waseda Univ., 4. Inst. Adv. Res. Biosyst. Dynam., Waseda Res. Inst. Sci. Eng., Waseda Univ.)
Comment()

[1P-888(1AS-17-07)]Development of a classification model to distinguish cancer from normal epithelium using spatial transcriptomics of colorectal cancer tissue

○Shunsuke A Sakai1,2, Ryosuke Nomura1,3, Masaki Ohira1,2, Kyoko Kurihara1,2, SungGi Chi1, Yuki Matsubara1, Yukiko Morinaga4, Ken Kato4, Kojima Motohiro4, Ayako Suzuki3, Yutaka Suzuki3, Katsuya Tsuchihara1,2, Shun-Ichiro Kageyama1, Riu Yamashita1,3 (1. Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 2. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 3. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 4. Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine)
Comment()

[1P-889]A novel photosensitizer-conjugated antibody exerting anti-tumor effects in tumor-bearing mouse

○Toshiyuki Goto1, Sally Danno1, Chie Ueda1, Kumi Tsutsumi1, Yosky Kataoka1 (1. Kobe university)
Comment()

[1P-890]Functional evaluation of an immune regulatory molecule in pancreatic cancer progression

○Rieko Aihara1, Juri Ichikawa1, Kuniyuki Kawano1,2, Ren Koyama1, Shingo Kato3, Hiroshi Okuda1, Tomohiko Tamura1,4 (1. Department of Immunology, Yokohama City University, 2. Department of Gastroenterology, Yokohama City University, 3. Department of Clinical Cancer Genomics, Yokohama City University Hospital, 4. Advanced Medical Research Center, Yokohama City University)
Comment()

[1P-891]The role of p16Ink4a-expressing senescent hepatocytes in the progression from metabolic dysfunction-associated steatohepatitis to hepatocellular carcinoma

○Zixue Zhang1, Yasuhiro Nakano1,2, Soichiro Kumamoto1, Hiroshi Inoue3, Yoshikazu Johmura1,2 (1. Div. Cancer Senescence Biol., Cancer Res. Inst., Kanazawa Univ., 2. Integrated Systems of Aging Res., Inst. Frontier Sci. Initiative, Kanazawa Univ., 3. Metab. Nut. Res., Inst. Frontier Sci. Initiative, Kanazawa Univ.)
Comment()

[1P-892]Contribution of DACH1 expression in tumor endothelial cells to tumor growth

○Takumi Shimbori1, Airi Morishita2, Ryuki Nishimura2, Minori Ozaki1, Koki Sato1, Haruko Hayasaka1,2,3 (1. Dept. Sci., Grad. Sch. Sci. Eng., Kindai Univ., 2. Dept. Life Sci., Fac. Sci. Eng., Kindai Univ., 3. Res. Inst. of Sci. and Tech., Kindai Univ.)
Comment()

[1P-893(1AS-08-05)]Identification and functional analysis of germline mutations associated with recurrence in colorectal cancer

○Masaki Ohira1,2, Yoshiaki Nakamura3, Masao Nagasaki4,5, Takao Fujisawa3, Tadayoshi Hashimoto3, Jun Watanabe6, Saori Mishima7, Hiromichi Ebi8, Hideaki Bando3, Ichiro Takemasa9, Takeshi Kato10, Daisuke Kotani7, Eiji Oki11, Takayuki Yoshino7, Katsuya Tsuchihara1,2, Riu Yamashita1,12 (1. Division of Translational Informatics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 2. Department of Integrated Biosciences, Graduate school of Frontier Sciences, The University of Tokyo, 3. Translational Research Support Office, National Cancer Center Hospital East, 4. Division of Biomedical Information Analysis, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 5. Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, 6. Department of Colorectal Surgery, Kansai Medical University, 7. Department of Gastrointestinal Oncology, National Cancer Center Hospital East, 8. Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, 9. Department of Gastroenterological Surgery, Osaka International Medical & Science Center, 10. Department of Surgery, NHO Osaka National Hospital, 11. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 12. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)
Comment()

[1P-894]Contribution of endothelial DACH1 expression to tumor growth in mouse colon cancer

○Minori Ozaki1, Azusa Sato2, Takumi Shimbori1, Haruko Hayasaka3,1,2 (1. Dept. Sci., Grad. Sch. Sci. Eng., Kindai Univ., 2. Dept. Life Sci., Fac. Sci. Eng., Kindai Univ., 3. Res. Inst. of Sci. and Tech., Kindai Univ.)
Comment()

[1P-895]Novel Short RNA Analysis Approaches for Non-Invasive Diagnostics Using Body Fluids

○Yoshitake Sano1, Mitsuko Sugano1, Tomomi Ando1 (1. TOSHIBA)
Comment()

[1P-896]Exploration of Simplified Natural Products with Antitumor Activity and SAR Analysis

○Misaki Sato1, Tomoya Higashi1, Tomoki Hoshoya1, Humiya Seki2,3, Takahiko Hara2, Tetsuyuki Akashi4, Shingo Dan4, Takashi Hirano1, Nobuo Kitada1,5, Shojiro Maki1,6 (1. The University of Electro-Communications, 2. Tokyo Metropolitan Institute of Medical Science, 3. GRAD. SCHOOL OF SCIENCE, TOKYO METROPOLITAN UNIVERSITY, 4. TEH CANCER CHEMOTHERAPY CENTER OF JFCR, 5. Coordinated Center for UEC Research Facilities, 6. CENTER FOR NEUROSCIENCE AND BIOMEDICAL ENGINEERING)
Comment()

[1P-899]Improved library and data quality for cancer panel sequencing through the adoption of gel purification

○Ryota Kajihara1, Mima Ogawa1, Takahide Yokoi1 (1. Hitachi, Ltd. Research & Development Group)
Comment()

[1P-900]Establishment of long-lived rodents, Damaraland mole-rat skin fibroblasts exhibit cell death resistance similar to naked mole-rat fibroblasts.

○Yusuke Suzuki1,2, Kanta Yamaguchi1, Kaitlyn N. Lewis Hardell3, Kurumi Ota1,2, Taira Kamikado1, Yoshimi Kawamura1,2, Rochelle Buffenstein3,4, Kaori Oka1,2, Kyoko Miura1,2 (1. Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University, 2. Laboratory of Longevity and Stem Cell Biology, Department of Stem Cell Biology and Medicine, Graduate School of Medical Science, Kyushu University., 3. Calico Life Science LLC, South San Francisco., 4. Department of Biological Sciences, University of Illinois.)
Comment()

[1P-901]Analysis of Age-Related Changes in the Damaraland Mole-Rat, a Long-Lived Rodent

○Kurumi Ota1, Yusuke Sakai2, Koki Sekiguchi3, Yusuke Suzuki3, Nagaki Ohnuki5,6, Miyuki Kanda5,6, Keisuke Okuhara6,5, Hidemasa Bono5,4, Kaori Oka3, Kyouko Miura1 (1. kyushu Univ., 2. Japan Institute for Health Security, 3. Kumamoto Univ., 4. Hiroshima Univ., 5. Hiroshima Univ. Genome Editing Innovation Center, 6. PtBio)
Comment()

[1P-902]Quantitative and systematic behavioral profiling reveals social complexity in eusocial naked mole-rats

○Masanori Yamakawa1,2,3,4, Takahiro Ezaki5, Akiyuki Watarai4, Nobuyuki Kutsukake6, Kyoko Miura1,2, Teruhiro Okuyama4 (1. Kumamoto Univ., 2. Kyushu Univ., 3. SOKENDAI (ESB), 4. Univ. of Tokyo (IQB), 5. Univ. of Tokyo (RCAST), 6. SOKENDAI (RCIES))
Comment()

[1P-903]Oncogene HRasV12 transduction induced brain tumors in Naked-mole rats, cancer-resistant animals

○KAZUKI NAKAMURA1,2, YOSHIMI KAWAMURA1,2, NOBUYUKI OHNISHI3,4, YUKIO FUJIWARA5, YOSHIHIRO KOMOHARA5, HIDEYUKI SAYA6, KAORI OKA1,2, KYOKO MIURA1,2 (1. Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University,, 2. Laboratory of Longevity and Stem Cell Biology, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 3. Department of Clinical Diagnostics Oncology, Clinical Research Institute for Clinical Pharmacology and Therapy, Showa University, 4. Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 5. Department of Cell Pathology, Faculty of Life Sciences, Kumamoto University, 6. Oncology Innovation Center, Fujita Health University)
Comment()

[1P-904]Analysis of factors and mechanisms underlying skin color changes in the longest-lived rodent, the naked mole-rat

○Maki Nakamoto1,2, Riyo Yamasaki2, Yoshimi Kawamura2, Kaori Oka1,2, Kyoko Miura1 (1. Laboratory of Longevity and Stem Cell Biology, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2. Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University)
Comment()

[1P-905]In vivo evidence for cancer resistance in the Damaraland mole-rat

○Koki Sekiguchi1,2, Kaori Oka1,2, Mari Nagase1, Yui Sano1,2, Maki Nakamoto1,2, Kurumi Ota1,2, Mika Kobe1,2, Naho Onoue1,2, Nanami Inoue1,3, Tsubasa Mikawa1,4, Yusuke Sakai5, Satoko Sakurai6, Yukio Fujiwara7, Yoshimi Kawamura1,2, Takuya Yamamoto6,8,9, Rochelle Buffenstein10,11, Yoshihiro Komohara7, Kyoko Miura1,2 (1. Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University, 2. Laboratory of Longevity and Stem Cell Biology, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 3. Kumamoto Gakuen University Fuzoku High School, 4. Kamoto High School, 5. Department of Pathology, National Institute of Infectious Diseases, 6. Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, 7. Department of Cell Pathology, Faculty of Life Sciences, Kumamoto University, 8. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, 9. Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), 10. Calico Life Sciences LLC, 11. Presently at Department of Biological Sciences, University of Illinois)
Comment()

[1P-906(1AS-13-04)]Stoichiometric Coordination of Coenzymes and Enzymes as a Basis for Intracellular Homeostasis

○Yasushi Kojima1, Emi Mishiro2, Teruaki Fujishita1, Rie Kajino1, Tomoyoshi Soga3, Masahiro Aoki1,4 (1. Aichi Cancer Center, 2. Nagoya Univ. WPI-ITbm, 3. Keio Univ., 4. Nagoya Univ.)
Comment()

[1P-908]Urea cycle is regulated by FoxO transcription factors through binding to hepatic Ass1 enhancer

○Samia Karkoutly1, Yoshinori Takeuchi1, Zahra Mehrazad Saber1, Chen Ye2, Duhan Tao2, Tsolmon Mendsaikhan1, Rika Saikawa1, Yuichi Aita2, Yuki Murayama2, Akito Shikama4, Yukari Masuda3, Naoya Yahagi1,2 (1. Jichi Medical University , 2. Tsukuba University, 3. Tokyo University, 4. Ibaraki Prefectural Central Hospital)
Comment()

[1P-909]Factorial investigation of Poor-Growth-Axolotl that does not recover with nutritional supplementation

○Haruka Axolotl Sugiyama1, Ya!min Beans1, Yu Asumi1, Santako F.N.1, Ryuki Ambystoma Tatsuoka2 (1. HAL lab Axolotl, 2. Ambystoma Lab)
Comment()

[1P-910]Glyceraldehyde-Induced Glycation Generates MG-H1- and Ubiquitin-Like-Modified DNA–Protein Cross-Links and Activates the DNA Damage Response in Cardiomyocytes

○Kenji Takeda1,2, Hironobu Akao2, Akiko Sakai-Sakasai1, Kouji Kajinami3, Masayoshi Takeuchi1 (1. Department of Advanced Medicine, Medical Research Institute, Kanazawa Medical University, 2. Department of Cardiology, Kanazawa Medical University, 3. Department of Sports Medical Science, School of Medical Technology, Teikyo University)
Comment()

[1P-911]A neuropeptide CG14075/Marmite is a novel hormone regulating starvation-dependent amino acid catabolism in Drosophila melanogaster

○Yuto Yoshinari1, Maiko Abe3, Ryo Hoshino3, Yosuke Mizuno3, Yoshitomo Kurogi3, Eisuke Imura3, Fuminori Tsuruta4, Akira Nakamura5,6, Ryusuke Niwa2, Takashi Nishimura1 (1. IMCR, Gunma univ., 2. TARA, Univ. of Tsukuba, 3. Grad School of Life and Environmental Sciences, Univ. of Tsukuba, 4. Institute of Life and Environmental Sciences, Univ. of Tsukuba,, 5. Institute of Molecular Embryology and Genetics, Kumamoto Univ., 6. Grad School of Pharmaceutical Sciences, Kumamoto Univ.)
Comment()

[1P-912]Inter-organ metabolic feedback via BCAA catabolism regulates the secretion of glucagon-like hormone in Drosophila

○Takashi Nishimura1, Chisei Arakawa1,2, Yuto Yoshinari1 (1. IMCR, Gunma Univ., 2. Faculty of Med., Gunma Univ.)
Comment()

[1P-913]Function of the glucagon-like hormone Akh against dehydration stress in the fruit fly Drosophila

○Chisei Arakawa1,2, Yuto Yoshinari2, Takashi Nishimura2 (1. Faculty of Medicine, Gunma University, 2. Institute for Molecular and Cellular Regulation, Gunma University)
Comment()

[1P-914]Adipocyte Differentiation and Energy Metabolism Mediated by ACOD1

○Keita Maki1,2, Hayashi Yoshikazu1,3,4, Ichiro Takahashi2, Masato Hirata3, Jimi Eijiro1,5, Yasukouchi Tomoyo1 (1. Kyushu Univ. OBT, 2. Kyushu Univ. Orthodontics, 3. Fukuoka Dental Univ. anatomy and cell biology, 4. Fukuoka Dental Univ. oral medicine, 5. Kyushu Univ. Molecular and Cellular Biochemistry)
Comment()

[1P-915]Significance of vitamin D3 in embryo implantation

○Susumu Tanaka1, Kotoha Takaki1, Ayaka Tanaka1, Namika Yoshida1 (1. University of Nagasaki, Siebold)
Comment()

[1P-916]Ergothioneine regulates embyryo implantation

○Namika Yoshida1, Hiromi Murata2, Hidetaka Okada2, Susumu Tanaka3 (1. Nutritional Science Course, University of Nagasaki, Siebold., 2. Department of Obstetrics and Gynecology, Kansai Medical University., 3. Department of Nutrition and Health, University of Nagasaki, Siebold.)
Comment()

[1P-917(1AS-07-04)]Enteroendocrine L cells secrete neurotransmitters in response to sugars and amino acids

○Yo Ito1, Kazuki Harada2, Yuri Yoshiike1, Ken Ueda1, Takashi Tsuboi1 (1. Graduate School of Arts and Sciences, The University of Tokyo, 2. Health and Environmental Risk Division, National Institute for Environmental Studies)
Comment()

[1P-918]Wdr6 Deficiency Alleviates Obesity via Enhanced Lipid Metabolism and Reduced Fat Storage

○Issa Furihata1, Jinyun Wang1, Tatsunobu Nakagawa1, Akihito Ishigami2, Yoshitaka Kondo2, Toshimitsu Komatsu3, Isao Shimokawa4, Takuya Chiba1 (1. Biomedical Gerontology Laboratory, School of Human Sciences, Waseda University., 2. Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology., 3. Biomedical Research Support Center, School of Medicine, Nagasaki University., 4. Institute of Biomedical Sciences, Nagasaki University.)
Comment()

[1P-919]E.a.LPS contained in brown rice activates small GTPase Rab5.

○Makoto Hagiwara1, Yasuhito Shimada3,4, Liqing Zang4,5, Tadasato Nagano1, Matsushita Kenji2,6 (1. Univ. of Niigata Prefec., 2. NCGG, Dep. of Oral Dis., 3. Dep. of Integ. Pharm., Mie Univ. Grad. School of Med.e, 4. Mie Univ. Zebrafish Research Center, 5. Grad. School of Reg. Innov. Stud., Mie Univ. , 6. Ogaki Woman's College, Dep. Dental Hygiene)
Comment()

[1P-920(1AS-14-07)]Zinc deficiency promotes steatosis via the reduction in H3K14ac

○Satoshi Takenaka1, Takao Fujisawa1,2, Hidenori Ichijo1 (1. Advanced Research Departments, Institute of Science Tokyo, 2. Graduate School of Pharmaceutical Sciences, The University of Tokyo)
Comment()

[1P-921]Characterization of Nutrient Transport Functions Using a Novel 2D Monolayer Model Derived from Region-Specific Mouse Small Intestinal 3D Organoids

○Yuta Takase1, Yoshiko Murata1, Toshio Takahashi1 (1. Bioorganic Research Institute, Suntory Foundation for Life Sciences)
Comment()

[1P-922]Sex-Specific Effects of Edible Cricket Gryllus assimilis Constituents on Body Weight Gain and Lipid Accumulation

○Kaede Yoshida1, Lisa Amanda Sugawara2, Haruka Hosoki2, Toru Asahi1,2,3,4, Kosuke Kataoka3,5, Chihiro Nozaki6 (1. Waseda University, Department of Advanced Science and Engineering, Major in Bioscience, 2. Waseda University, Graduate School of Advanced Science and Engineering, Department of Life and Medical Sciences, 3. Waseda University, Research Organization for Science and Engineering, 4. Waseda University, Nano-Life Innovation Research Organization, 5. Tokyo University of Agriculture and Technology, Institute of Engineering, Department of Bio-Functions and Systems Science, 6. Waseda University, Faculty of Science and Engineering, Center for International Programs in Science and Engineering)
Comment()

[1P-923]The Shin-MassBank project: Generation of high-quality product ion spectra from public metabolome datasets from metabolome data repository

○Fumio Matsuda1, Hayasaka Ryosuke4, Taihei Torigoe2, Yushi Takahashi3, Masatomo Takahashi2, Takaki Oka5, Yuki Matsuzawa5, Takato Kiuchi3, Akiyasu C. Yoshizawa3, Yoshihiro Izumi2, Hiroshi Tsugawa5, Akiyoshi Hirayama4, Shujiro Okuda3 (1. Univ. Osaka, 2. Kyushu Univ., 3. Niigata Univ., 4. Keio Univ., 5. Tokyo Univ. Agr. Tech.)
Comment()

[1P-924(1AS-07-03)]The mechanism whereby fatty acid intake confers cold tolerance on the fly

○Honoka Morioka1,2, Yusuke Hara2, Kenta Tomihara2, Daisuke Yamamoto2, Kosei Sato1,2 (1. University of Hyogo, 2. Advanced ICT Research Institute, NICT)
Comment()

[1P-925]Investigation of Oxidative Stress Distribution in the Liver Using the In Vivo Iron Dynamics Visualization Tool “LiON”

○Ayato Maeda1,2, Akihiro Nita2, Toshiro Moroishi2 (1. Mol. & Med. Pharm., Kumamoto Univ. , 2. Cellular Dynamics, Science Tokyo)
Comment()

[1P-926]Functional analysis of Dve in Drosophila larval fat body

○Tomoki Hayashida1, Ruoya Han, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life, Natl. Sci. Tech., Okayama Univ.)
Comment()

[1P-927]Hepatic FNDC5 Gene Therapy Alleviates Hyperglycemia and Diabetes Symptoms in Akita Mice

○Wen-Bin Lu1, Yi-Shan Huang2, Tzu-Teng Tai3, Hsu-Wen Chao4, Ming-Hong Tai1 (1. Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan., 2. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung, Taiwan, 3. Department of Biopharmaceutical Science, National Sun Yat-sen University, Kaohsiung, Taiwan, 4. Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan)
Comment()

[1P-928]NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene programs to improve glucose homeostasis

○Kaede Saito1, Yuta Hiraike2 (1. Division for Health Service Promotion, The University of Tokyo, 2. Laboratory for Advanced Research on Pathophysiology of Metabolic Diseases, Graduate School of Medicine, The University of Tokyo)
Comment()

[1P-929]Attribute analysis of Porphyromonas gingivalis fimA type IV detected in saliva of 348 university students

○Kentaro Nagamine1, Rei Okabe1, Nakata Eriko2 (1. Hiroshima International University, 2. Setsunan University)
Comment()

[1P-930]Loss of function in the systemic taste receptor TAS1R3 confers resistance to diet-induced obesity

○Anna Yoshimura1,2, Takuma Matsubara2, Hiroshi Takeuchi1, Shoichiro Kokabu2 (1. Division of Applied Pharmacology, Kyushu Dental University, 2. Division of Biochemistry, Kyushu Dental University)
Comment()

[1P-931]Effects of Vegetables on Inflammation Between Macrophages and Pancreatic β-Cells and on the Reduction of Insulin Secretion

○So Wakasa1, Takahiro Inoue1, Mohri Shinsuke1, Eri Mukai1 (1. Ritsumeikan Univ.)
Comment()

[1P-933]Investigation of the Molecular Mechanisms by which CEBPE Variants Contribute to Pathogenesis of Primary Immunodeficiency

○Tomoya Tamaru1, Atsushi Ueda2, Hirokazu Kanegane3, Taizo Wada4, Aaqib Zaffar Bandy5, Tadayuki Akagi1 (1. Fukuoka Institute of Technology, 2. Tokai Univ., 3. Institute of Science Tokyo, 4. Kanazawa Univ., 5. GMC Srinagar, Pediatrics, India)
Comment()

[1P-934]Functional characterization of human-like compound POLE mutations in zebrafish reveals critical role of Thr1980 in hematopoiesis

○Sui Aiyi1,2, Maeda Hiroki1, Tamaoki Junya 1, Ishiguro Tomoaki4, Takeuchi Ichiro5, Ogawa Ayame4, Kato Takashi3,4, Ishiguro Akira6,7, Kobayashi makoto1 (1. Department of Molecular and Developmental Biology, Institute of Medicine, University of Tsukuba,, 2. Doctoral Program in Medical Science, Degree Programs in Comprehensive Human Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 3. Department of Biology, Faculty of Education and Integrated Arts and Sciences, Waseda University, Tokyo, 4. Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University,, 5. Center for Pediatric Inflammatory Bowel Disease, Division of Gastroenterology, National Center for Child Health and Development, 6. Clinical Research Center, National Center for Child Health and Development, 7. Department of Pediatrics, NHO Disaster Medical Center)
Comment()

[1P-935]Development of a Diagnostic AI System for Japanese MODY Patients

○Manaka Tanaka1, Kazuyoshi Hosomichi1, Yukio Horikawa2,3 (1. Laboratory of Computational Genomics, Graduate School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, 2. Department of Diabetes, Endocrinology and Metabolism, Graduate School of Medicine, Gifu University, Gifu, Japan, 3. Clinical Genetics Center, Gifu University Hospital)
Comment()

[1P-936]DMD exon skipping therapy using Type I-D CRISPR-Cas, TiD-X

○Miyu Asari1, Rie Akamatsu1, Akiyoshi Kawaoka1, Hayuna Saito1, Kohei Kawaguchi1, Satoshi Kidokoro1, Naoki Wada2, Keishi Osakabe2, Yuriko Osakabe1 (1. Sch. of Life Sci. & Tech., Science Tokyo., 2. Grad. Sch. of Tech., Ind. & Soc. Sci., Tokushima Univ.)
Comment()

[1P-937]In situ detection of activation of calpain-3, a responsible gene product for LGMDR1, in mouse skeletal myotubes

○Chihiro Hisatsune1, Fumiko Ouchi1, Shoji Hata1, Yasuko Ono1 (1. Tokyo Metropolitan Institute of Medical Science)
Comment()

[1P-938]Pathophysiology and Causal Analysis of the Spontaneous Mutant Mouse pocy Showing Polycythemia

○Kumiko Yoshinobu1, Yuri Kitamoto1, Konomi Masuda1, Ryusei Hayashida1, Yutaka Takaoka2, Tadashi Kaname3, Kimi Araki1, Masatake Araki1 (1. IRDA, Kumamoto Univ., 2. Div. Bioinfo, Univ. of Toyama, 3. Genom Med, NCCHD)
Comment()

[1P-939]Analysis of Treacher Collins syndrome 4-associated mutations in Schizosaccharomyces pombe

○Kei Kawakami1, Hiroaki Kato1 (1. Shimane University)
Comment()

[1P-940]Dysregulation of the autoregulatory enhancer region by transposon insertion causes ectopic expression of Ptf1a in Danforth’s short tail (Sd) mice.

○Midori Tokuyasu1, Yuka Matsura1, Airi Hirayama1, Michihiko Sugimoto2, Masatake Araki1, Kimi Araki1 (1. IRDA, Kumamoto Univ., 2. Hyogo Medical Univ.)
Comment()

[1P-941(1AS-10-02)]Lamin A/C-driven nuclear envelope maturation is required for postnatal heart maturation

○Katano Wataru1, Alexis Stutzman2, Briana Thomas1, Melanie Gucwa1, Hanumakumar Bogireddi1, Atsuki En1,3, Kohta Ikegami1,4 (1. Cincinnati Children's Hospital Medical Center, 2. The University of Chicago, 3. Yokohama City University, 4. University of Cincinnati College of Medicine)
Comment()

[1P-942]Elucidation of How Aging-Related Phenotypic Changes in Endothelial Cells Induce Matrisome Accumulation in Brain Blood Vessels

○Sho Kitahara1, Taisuke Kato2, Sachiko Hirokawa2, Kazuki Tainaka3, Osamu Onodera1,2 (1. Department of Neurology, Brain Research Institute, Niigata University, 2. Department of Molecular Neuroscience, Brain Research Institute, Niigata University, 3. Department of System Pathology for Neurological Disorders, Brain Research Institute, Niigata University)
Comment()

[1P-944]Validation of the novel AAV vector that amplifies heart-specific gene expression for cardiac gene therapy

○Ayako Onizuka1, Ken Matsuoka1,2, Hijiri Inoue1, Hyejin Jo1, Seiji Takashima1,2 (1. Osaka University Graduate School of Frontier Biosciences, 2. Osaka University Graduate School of Medicine)
Comment()

[1P-945]Epigenetic alteration in Nsd2-KO mice, the models for Wolf-Hirschhorn syndrome

○Junko Tomikawa1, Chiharu Tayama1, Shiori Kinoshita1, Yuka Takayama1, Eriko Ohnishi1, Hiromi Kamura1, Keisuke Ishiwata1, Kazuaki Kojima1, Hiroki Kikuchi1, Shuji Takada1, Miho Terao1, Kazuhiko Nakabayashi1, Kenichiro Hata2, Tomoko Kawai1 (1. National Research Institute for Child Health and Development, 2. Gunma University Graduate School of Medicine)
Comment()

[1P-946]Elucidating the Role of Myokine FNDC5/Irisin and Pro-Fibrosis Signaling Pathways in Diabetic Cardiomyopathy

○Yi-Shan Huang1,3, Wen-Bin Lu2, Hsu-Wen Chao4, Chang-Yi Wu1,3, Ming-Hong Tai1,2 (1. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University, Kaohsiung, Taiwan, 2. Institute of Biomedical Sciences, National Sun Yat-sen University, Taiwan, 3. Department of Biological Sciences, National Sun Yat-sen University, Taiwan, 4. Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan)
Comment()

[1P-947]Loss of Mucin-Type O-Glycans Leads to Synaptic Defects
in a Drosophila Model of the Congenital Disorder
of Glycosylation SLC35A2-CDG

○Kazuyoshi Itoh1, Masaki Kurogochi2, Tadashi Kaname3, Jun-ichi Furukawa2, Shoko Nishihara1 (1. Soka University, 2. Nagoya University, 3. National Center for Child Health and Development)
Comment()

[1P-949]Development of a cost-effective method to produce lysostaphin, an antimicrobial protein specific to Staphylococcus aureus, using an etiolated rice seedling

Hayato Kayukawa1, Ryota Shimizu1, Akiko Watanabe1, So Shimoda1,2, Ryuta Tobe1, Hiroshi Yoneyama1, ○Yukihiro Ito1 (1. Tohoku Univ, 2. Present) NARO)
Comment()

[1P-950]Loss-of-function in mitochondrial RNA polymerase restores pollen fertility in cytoplasmic male sterile tomato

○Kosuke Kuwabara Kuwabara1, Rika Nakajima2, Alexis Van Bosstraeten3, Kentaro Ezura4,5, Kinya Toriyama1, Tohru Arizumi5, Kenta Shirasawa6 (1. Grad. Sch. Agric. Sci., Tohoku Univ., 2. Grad. Sch. Agri. Life Sci., Univ. Tokyo, 3. Grad. Sch. Sci. and Tech., Univ. Tsukuba, 4. JIRCAS, 5. Fac. Life Env. Sci., Univ. Tsukuba, 6. Kazusa DNA Res. Inst.)
Comment()

[1P-951]Effects of light quality on growth and expression of nodulation-related genes in soybean

○Nanoha Tsuruoka1, Mina Matsubara3, Kazuaki Mawatari3, Mutsumi Aihara1, Akira Takahashi3, Katsuyuki Miyawaki1,2 (1. Tokushima Univ., 2. BIRC, Tokushima Univ., 3. Biomed, Sci, Tokushima Univ.)
Comment()

[1P-952]Polycistronic tRNA-gRNA (PTG)-Mediated Multiplex Genome Editing of Endogenous Gene Family in Rice

○Kazuhito Akama1, Yasushi Yukawa2 (1. Shimane University, 2. Nagoya City University)
Comment()

[1P-953]Molecular mechanism of Isoprene Signaling Pathway in Arabidopsis thaliana

○Mizuki Tsutsui1, Sayaka Okamoto1, Toshiro Ito1, Nobutoshi Yamaguchi1 (1. Grad. Sch. of. Biol. Sci, Nara inst. of. Sci. and Tech.)
Comment()

[1P-954]Diversity of Regulatory Mechanisms of Parental Imprinted Genes in Seed and Endosperm Development

○Kazushi Kamada1, Keishiro Yamada1, Tamaki Shitabo1, Yuko Wada1, Seiji Takayama2, Toshiro Ito1 (1. Grad. Sch. of. Biol. Sci, Nara Inst. of. Sci. and Tech., 2. Grad. Sch. of. Agri. Life Sci. Tokyo Univ.)
Comment()

[1P-955]Molecular Basis of Petal Abscission Controlled by Jasmonic Acid and Ethylene

○Yudai Takenaka1, Yuki Furuta1, Koki Nakamura1, Nobutoshi Yamaguchi1, Toshiro Ito1 (1. Nara Institute of Science and Technology)
Comment()

[1P-956]Functional analysis of paternal imprinted genes in white flower shepherd's purse endosperm

○Hinata Oike1, Tamaki Shitabo1, Wei Chen2, Seiji takayama3, Bo Sun2, Yuko Wada1, Toshiro Ito1 (1. Nara Institute of Science and Technology, 2. Nanjing Univ., 3. Tokyo Univ.)
Comment()

[1P-957]Identification of HSFA2-Interacting Factors Involved in Heat Stress Memory in Plants

○Kanami Watanabe1, Natsuki Tanaka1, Toshirou Itou1, Nobutoshi Yamaguchi1 (1. Nara Institute of Science and Technology)
Comment()

[1P-958]Detection of changes in gene expression during exposure to low-doses of radiation in Arabidopsis thaliana

○Shinya Takahashi1,2,3, Satoru Araya2,3, Masanori Tamaoki4 (1. ILES, Univ. Tsukuba, 2. BRES, Univ. Tsukuba, 3. T-LSI, Univ. Tsukuba, 4. Biodiversity. Div., Natl. Inst. Env. Stud.)
Comment()

[1P-959]In Vitro Investigation of Nitrosating Agents and Cofactors in Areca Nut-Specific N-Nitrosamine Formation

○Min-Chen Chang1, Ting-Yu Kuo2, Yu-Han Chen2, Chiung-Wen Hu2, Mu-Rong Chao1, Yuan-Jhe Chang1 (1. Department of Occupational Safety and Health, Chung Shan Medical University, 2. Department of Public Health, Chung Shan Medical University)
Comment()

[1P-960]Elucidating a new role for ABA in lateral root growth regulation

○Sara Neyrot1,2, Yukari Nagatoshi 2, Chieko Goto4,3, Hidehiro Fukaki3, Yasunari Fujita1,2 (1. Univ. of Tsukuba, 2. JIRCAS , 3. Kobe Univ., 4. UOsaka)
Comment()

[1P-961]Analysis of virulence function of the rice blast pathogen effector AVR-Pik

○MISATO MUTO1, TAKAHIKO KOIZUMI1, KOSUKE YAMAMOTO1, HIROMASA SAITOH1 (1. Tokyo University of Agriculture)
Comment()

[1P-962]Benchmarking and validation of a custom-made and open-source multi-mode microbial colony/biofilm imaging system.

○Ryunosuke Sakai1, Yifan Zhao1, Martin Robert1 (1. Kyoto Univ.)
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[1P-963]Identification of genes associated with diverse temperature adaptation in natural Arabidopsis thaliana populations

○Sawa Okada1, Daigo Okada2,3,4, Yoshiaru Yamamoto1,5,6,7 (1. Gifu Univ. UGSAS, 2. Gifu Univ. Grad School of Medicine, 3. Gifu Univ. GUiAS, 4. NII, 5. Gifu Univ. Faculty of Applied Biological Sciences, 6. Gifu Univ.Grad School of Natural Science and Technology., 7. RIKEN)
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[1P-966]Inflammation-associated molecules in the glomerular-endothelium in mild IgA-nephropathy patients identified by single-cell and spatial transcriptome

Kumi Hasegawa2, ○Nagako Kawashima1, Ayako Kawabata2, Megumi Sakakura2, Naoki Onoda2, Takashi Sano1, Itaru Urakawa2, Masahiro Matsubara2, Shokichi Naito1 (1. Kitasato University, 2. Kyowa Kirin Co., Ltd.)
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[1P-967(1PS-11-04)]Pregnancy-responsive fibroblast controls physiological skin remodeling as a mechano-to-chemical signaling hub

○Yoshihiko Kobayashi1,2, Kazunori Sunadome3,4, koichiro Maki2,5, Hiroki Fukunaga6, Hitomi Matsubara7, Taiji Adachi2,5, Ken-ichi Matsumoto8, Mitsuhiro Iwaki6,9,10,11, Takuya Yamamoto3,4,12, Fumiko Toyoshima1,2 (1. MRL, Science Tokyo, 2. LiMe, Kyoto Univ, 3. CiRA, Kyoto Univ, 4. ASHBi, Kyoto Univ,, 5. Graduate School of Engineering, Kyoto Univ, 6. Adv ICT Res Inst, NICT, 7. IMS, RIKEN, 8. Interdisciplinary Center for Science Research, Shimane Univ, 9. BDR, RIKEN, 10. IFReC, Univ Osaka, 11. FBS, Univ Osaka, 12. AIP, RIKEN)
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[1P-968]Therapeutic Effects and Mechanistic Analysis of Molecular Hydrogen on Acute Liver Injury in a Diabetic Mouse Model

○Naomi Kamimura1, Katsuya Iuchi2, Tsutomu Igarashi3, Ikuroh Ohsawa4, Chikako Nito1, Jitsuo Usuda1, Shigeo Ohta5 (1. Lab. Clin. Res., Collab. Res. Ctr., Nippon Med. Sch., 2. FRIS, Tohoku Univ., 3. Dept. Ophthalmology, Nippon Med. Sch., 4. Mol. Hydrogen Med., TMIG, 5. Dept. Neurol. Med., Grad. Med. Sch., Juntendo Univ.)
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[1P-969]Microcystin-LR exacerbates chronic kidney disease in rats: insights into gut microbiome and host proteome dysregulation

○Suppakrit Kongsintaveesuk1,2,8, Keerapach Tunbenjasiri2,8, Thatsanapong Pongking2,8, Sitiruk Roytrakul3, Sawanya Charoenlappanit3, Sirirat Anutrakulchai4,8, Chawalit Pairojkul5,8, Kitti Intuyod5,8, Pakornkiat Tanasuka5,8, David Blair6, Somchai Pinlaor7,8, Porntip Pinlaor1,8 (1. Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences., Khon Kaen University, Khon Kaen, Thailand, 2. Biomedical Sciences program, Graduate School, Khon Kaen University, Khon Kaen, Thailand, 3. Functional Proteomics Technology Laboratory, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand, 4. Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 5. Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 6. College of Science and Engineering, James Cook University, Townsville, Queensland, Australia, 7. Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 8. Chronic Kidney Disease Prevention in Northeastern Thailand (CKDNET), Khon Kaen University, Khon Kaen, Thailand)
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[1P-970]Camphorquinone attenuates liver fibrosis and hepatic stellate cell activation in vivo and in vitro

○Kil Hwan Kim1, Ok Kyung Choi1, Hak Su Kim1, Gwang Won Cho2, Jin Young Kim2, Jin Young Min1 (1. Veterans Health Service Medical Center, 2. Chosun University)
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[1P-971(1PS-10-05)]Elucidation of adverse effects of industrial chemicals and their underlying mechanisms using C. elegans

○Masahiro Tomioka1 (1. National Institute of Occupational Safety and Health, Japan)
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[1P-972]FoxO3a contributes to skin homeostasis by regulating mitochondrial dynamics

○Kurumi Ogata1, Mariko Moriyama1, Saki Asada1, Ryoichi Mori2, Hiroyuki Moriyama1 (1. kindai university, 2. nagasaki university)
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[1P-973(1PS-11-03)]FoxO3a Promotes Scarless Wound Healing

○Saki Asada1, Mariko Moriyama1, Shoji Imamichi2, Kurumi Ogata1, Ryoichi Mori2, Hiroyuki Moriyama1 (1. Kindai Univ., 2. Nagasaki Univ.)
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[1P-974]Establishing a Method to Evaluate Wastewater Purification Systems Using Drosophila melanogaster

○Koutarou Yoshida1, Tomoko Yamakawa1 (1. National Institute of Technology, Ibaraki College)
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[1P-975]descSPIM-Galaxy: A Next Generation DIY Light Sheet Microscope Enabling Ultra-Multicolor 3D Imaging for Tissue Clearing Applications

○Yuki Nozawa1,3, Kohei Otomo1,2,3,4,5, Etsuo A Susaki1,2,3,6 (1. Dept. Biochem. II, Fac. Med., Juntendo Univ., 2. Dept. Biochem. & Syst. Biomed., Grad. Sch. Med., Juntendo Univ., 3. Nakatani Biomed. Spatialomics Hub, Grad. Sch. Med., Juntendo Univ., 4. Div. Biophotonics, Natl. Inst. Physiol. Sci. (NIPS), Natl. Inst. Nat. Sci. (NINS), 5. Biophotonics Res. Grp., Explor. Res. Ctr. Life & Living Syst. (ExCELLS), Natl. Inst. Nat. Sci. (NINS), 6. Inst. Quantum Life Sci., Natl. Inst. Quantum Sci. & Tech. (QST))
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[1P-976]descSPIM-Fullmoon: A DIY Wide-Field Light-Sheet Microscope to Make Whole-Mouse-Brain Imaging More Accessible

○Kiyotada Naitou1, Kohei Otomo2,3, Etsuo A. Susaki2,3,4 (1. Kagoshima University, 2. Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine, 3. Nakatani Biomedical Spatialomics Hub, Juntendo University Graduate School of Medicine, 4. Institute for Quantum Life Science, National Institutes for Quantum Science and Technology)
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[1P-977]Realizing three-dimensional histopathology: clinical application of tissue clearing technology and light-sheet fluorescence microscopy

○Akira Leon Yoshikawa1,2,3,4, Yao Tianrun1, Yuki Nozawa1,2, Kohei Otomo1,2, Etsuo A Susaki1,2 (1. Juntendo Univ., 2. )Nakatani Biomed. Spatialomics Hub, 3. Kameda Med. Cent., 4. Nagasaki Univ.)
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[1P-978]Molecular network analysis of Disease multi-omics data.

○Rie Taniguchi1, Miki Shigetaka1, Yoko Inoue1, Nakako Iwasaki1, Mieko Ohota1, Kazuko Mashino1, Shizuka Miyahara1, Makoto Shigetaka1 (1. KM Data.Inc.)
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[1P-979]Type-2 Diabetes Mellitus Induced Endothelial Dysfunction via Elevated Reactive Oxygen Species

○Precella Silvia Samsumin1, Cat Khanh Vuong1, Osamu Ohneda1 (1. Graduate School of Comprehensive Human Science, Laboratory of Regenerative Medicine and Stem Cell Biology, University of Tsukuba, 1-1-1, Tsukuba, 305-8575, Japan)
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[1P-980]Mutant analysis of the heat-tolerance gene in C. elegans

Masami Shima2, Kiyoji Nishiwaki3, Takeru Matsuda4,2, ○Asuka Takeishi1,2 (1. Kobe University, 2. RIKEN, 3. Kwansei Gakuin University, 4. The University of Tokyo)
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[1P-981]Laboratory Rearing and Life History of Culicoides oxystoma

○Wen-Cheng Lin1, Wei-Ting Liu1 (1. National Chung Hsing University, Taichung 402202, Taiwan)
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[3P-642]Fertilizable rat sperm produced in a mouse body by blastocyst complementation: A novel, cost-effective strategy for generating genetically modified rats using ES cells

○Kenji Sakimura1, Rie Natsume1, Kosuke Murata2, Hiroaki Taketsuru1,3, Runa Hirayama1,4, Hideaki Yamashiro2, Keizo Takao4, Ena Nakatsukasa1, Manabu Abe1 (1. Department of Animal Model Development, Brain Research Institute, Niigata University, 2. Graduate School of Science and Technology, Niigata University, 3. Department of Comparative & Experimental Medicine, Brain Research Institute, Niigata University, 4. Department of Behavioral Physiology, Graduate School of Innovative Life Science, University of Toyama)
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[3P-766]Role of small Maf proteins in T cell immunity

○Masayuki Kitajima1, Harumi Suzuki1 (1. Dept. of Immunology and Pathology, National Institute of Global Health and Medicine)
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