Session Details
[3PS-16]【J】Analysis of working principle of a super complex system governed by RNA and its binding proteins
Fri. Dec 5, 2025 2:20 PM - 4:20 PM JST
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Room 16(Pacifico Yokohama Conference Center 5F, 502)
Organizer: Riki Kurokawa (Saitama Medical University), Masato Katahira (Kyoto University)
RNA-binding protein (RBP) TLS/FUS involved in phase separation binds thousands of RNAs. TLS forms complex with RBPs also binding thousands of RNAs. Then, the TLS complex consists of divergent RBPs and vast numbers of RNAs. Binding of RBP to RNA has both non-specific and specific ones. The binding is precisely regulated with necessity and coincidence. We plan a session of active people working on principle of the complex system, and expect to have a unique debate.
Introduction
[3PS-16-01]Analysis of RNA inducing phase separation and precipitation
○Riki Kurokawa1 (1. Saitama Medical University)
[3PS-16-02]The Effect of Loss of Neuromuscular Input on Skeletal Muscle Contraction and Molecular Changes
○Yoshitake Cho1 (1. University of California, San Diego, Dept. of Medicine)
[3PS-16-03]Regulation and Dynamics of the Nuclear Argonaute in Rice Reproduction
○Reina Komiya1,2 (1. RIKEN, 2. OIST)
[3PS-16-04]Dynamic Structural Changes of the Histone H3 Tail upon Chromatosome Formation
○Ayako Furukawa1, Masatoshi Wakamori2, Yasuhiro Arimura3, Hideaki Ohtomo4, Yasuo Tsunaka4, Hitoshi Kurumizaka3, Takashi Umehara2, Yoshifumi Nishimura4 (1. Kyoto Univ., 2. BDR, RIKEN, 3. Tokyo Univ., 4. Yokohama City Univ.)
[3PS-16-05(3P-147)]TFIID–Mediator complex interaction regulates transcriptional switching from initiation to elongation
○Kazuki Furugori1, Hidefumi Suzuki1, Ryota Abe1, Hidehisa Takahashi1 (1. Yokohama City Univ.)
[3PS-16-06(3P-163)]A Germ Cell-Specific RNA-Binding Protein Mediates Specific RNA Accumulation into Membraneless Organelles : The Molecular Mechanism and Functional Co-option in Cancer
○Mizuki Fukuda1, Hiroya Yamazaki1, Hideto Ito1, Yurika Namba1, Mikiko C Siomi1 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo)
[3PS-16-07(3P-372)]The role of the intrinsically disordered region of Coilin in Cajal body formation and recruitment of its constituent factors
○Ryota Yokoyama1, Shinichi Nakagawa1, Hiroshi Maita1 (1. Hokkaido University)
[3PS-16-08(3P-167)]Deciphering the RNA blueprint for a new principle of membraneless organelle assembly
○Sota Umezaki1, Tomohiro Yamazaki1, Sylvie Souquere2, Ichiro Taniguchi1, Hiro Takakuwa1, Gerard Pierron2, Tetsuro Hirose1,3 (1. FBS, Univ Osaka, 2. CNRS, 3. OTRI, Univ Osaka)
[3PS-16-09(3P-184)]Visualization of Nop56-Repeat Associated Non-AUG translation in living cells at single mRNA level
○AYAMU NOGUCHI1, Hayato Ito1, Timothy Stasevich2, Yoshitaka Nagai3, Hideki Taguchi1,4 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Biochem. and Mol. Biol., Colorado State University, 3. Faculty of Medicine, Kindai University, 4. Institute of Integrated Research, Institute of Science Tokyo)
[3PS-16-10]Analysis of interaction between nucleic acids aptamer and disease-causing target protein under in vitro and in-cell conditions
○Masato Katahira1 (1. Kyoto University)