[28-13-am] Drug Discovery, SAR 2

3:38 PM - 3:50 PM JST(6:38 AM - 6:50 AM UTC)

[28-13-pm12S] Structure-activity relationship studies of SARS-CoV-2 main protease inhibitors focused on fluorine substitutions

○Ryusei Yamamoto¹, Nobuyo Higashi-Kuwata², Kohei Tsuji¹, Takuya Kobayakawa¹, Takahiro Ishii¹, Kouki Shinohara¹, Shin-ichiro Hattori², Naoki Kishimoto³, Nobutoki Takamune³, Shogo Misumi³, Haydar Bulut⁴, Hironori Hayashi⁵, Hiroaki Mitsuya^2,4, Hirokazu Tamamura¹ (1. Laboratory for Biomaterials and Bioengineering, Institute of Science Tokyo, 2. Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, 3. Department of Environmental and Molecular Health Science, Faculty of Life Science , Kumamoto University, 4. National Cancer Institute, National Institutes of Health, 5. International Research Institute of Disaster Science, Tohoku University)