[27-17-pm] Gene DDS, Formulation Design/Manufacturing | The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

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Session Details

Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-17-pm]Gene DDS, Formulation Design/Manufacturing

Thu. Mar 27, 2025 1:15 PM - 2:51 PM JST
Thu. Mar 27, 2025 4:15 AM - 5:51 AM UTC

Room 17 (MARINE MESSE FUKUOKA Hall B: Conference Room2-1 [2F])

Chair: Teruki Nii, Sato Yuhki

1:15 PM - 1:27 PM JST(4:15 AM - 4:27 AM UTC)

[27-17-pm01S]Efficient delivery of immunosuppressive oligodeoxynucleotides to immune cells by ligand conjugation

○Chihiro Tanaka¹, Yuko Yokoyama¹, Shoko Itakura¹, Kosuke Kusamori¹, Makiya Nishikawa¹ (1. Fac. Pharm. Sci., Tokyo Univ. Sci.)

1:27 PM - 1:39 PM JST(4:27 AM - 4:39 AM UTC)

[27-17-pm02S]Cas9-sgRNA RNP delivery systems comprising tannic acid and fine-tuned boronic acid-conjugated polymers for tissue-selective in vivo genome editing

○Toshizumi Chino^1,2, Takumi Matsuo^1,2, Yuto Honda^1,2,3, Yuriko Osakabe¹, Haochen Guo³, Kyohei Muguruma^1,2, Yutaka Miura^1,2, Nobuhiro Nishiyama^1,2,3 (1. Dept. of Life Sci. and Tech., Science Tokyo, 2. Lab. for Chem. and Life Sci., Science Tokyo, 3. iCONM)

1:39 PM - 1:51 PM JST(4:39 AM - 4:51 AM UTC)

[27-17-pm03S]Development of orientation-controlled antibody-modified lipid nanoparticles using high functionality and quality lipids

○Makoto Matsumoto¹, Riku Takayama², Tatsunori Izumi¹, Hidefumi Mukai^1,2, Shigeru Kawakami^1,2 (1. Nagasaki University Graduate School of Biomedical Sciences, department of Pharmaceutical Informatics , 2. School of Pharmaceutical Sciences Nagasaki University)

1:51 PM - 2:03 PM JST(4:51 AM - 5:03 AM UTC)

[27-17-pm04S]Direct detection of capping by measurement of die wall pressure in rotary tableting machines

○Yusuke Imayoshi¹, Keigo Hanyu^1,2, Shuji Ohsaki¹, Hideya Nakamura¹, Satoru Watano¹ (1. Osaka Metro. U., 2. Meiji Co., Ltd.)

2:03 PM - 2:15 PM JST(5:03 AM - 5:15 AM UTC)

[27-17-pm05S]Preparation of mRNA-encapsulated extracellular vesicles (mRNA-EVs) for inhalation powder

○Kazuki Sato¹, Ogawa Koki¹, Tetsuya Ozeki¹ (1. Grad. Sch. Pharm. Sci., Nagoya City Univ.)

2:15 PM - 2:27 PM JST(5:15 AM - 5:27 AM UTC)

[27-17-pm06S]Evaluation of pH-dependent structural changes of lipid nanoparticles by cryo-TEM and NMR

○Yui Sakagawa¹, Keisuke Ueda¹, Kenjirou Higashi¹, Kunikazu Moribe¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

2:27 PM - 2:39 PM JST(5:27 AM - 5:39 AM UTC)

[27-17-pm07S]Stabilization and In Vivo Absorption Characteristics of Amorphous Drug Complexes with Two Parent Cyclodextrins

○Hiroto Ito¹, Fumitoshi Hirayama^1,2, Daisuke Iohara^1,2 (1. Grad. Sch. Pharm. Sci., Sojo Univ., 2. DDS Res. Insti., Sojo Univ.)

2:39 PM - 2:51 PM JST(5:39 AM - 5:51 AM UTC)

[27-17-pm08]Effects of improved solubility of phenytoin on nasal mucosa permeability and brain migration after intranasal administration

○Taiki Nagatomo¹, Kanon Nagasawa¹, Yuiko Kanbara¹, Naoto Suzuki¹, Toyofumi Suzuki¹ (1. School of Pharmacy, Nihon University)

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