Session Details

[27P-am]Evaluation of drug efficacy and safety, Chemotherapeutic agents, Kampo medicines, Others

Thu. Mar 27, 2025 8:30 AM - 12:00 PM JST
Thu. Mar 27, 2025 11:30 PM - 3:00 AM UTC
Poster (MARINE MESSE FUKUOKA Hall B: Exhibition Room [1F])

[27P-am217]The pharmacological mechanism of bufadienolides for the treatment of luminal-type non-muscle invasive bladder cancer

Chih-Chieh Tu1,2, Mei-Chuan Chen3, ○Chun-Han Chen1,2 (1. Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, 2. Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 3. School of Pharmacy, College of Pharmacy, Taipei Medical University)

[27P-am218]Elucidating the pharmacological mechanisms of phenanthridine Amaryllidaceae alkaloids in non-muscle invasive bladder cancer cells

Yu-Chi Su1, ○Mei-Chuan Chen1,2 (1. Master Program in Clinical Genomics and Proteomics, College of Pharmacy, Taipei Medical University, 2. School of Pharmacy, College of Pharmacy, Taipei Medical University)

[27P-am219]Cisplatin regulates the growth of cancer via PKM2 signaling

○Jing-Ru Weng1, Jui-Hsin Su2, Chun-Lin Chen3, Li-Yuan Bai4 (1. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, 2. National Museum of Marine Biology and Aquarium, Pintung, Taiwan, 3. Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan, 4. Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan)

[27P-am220]Effect of plant extracts on adipocyte maturation and lipid droplets degradation.

○Honoka Yuasa1, Keita Shigeyama1, Ikuyo Sakaguchi1 (1. CLUB COSMETICS CO., LTD.)

[27P-am221]Inhibitory effect of FAD041-C on H2O2-induced apoptosis in Neuro-2a cells

○Meiyan Xuan1, Toshiya Aoyama1, Haruka Shimasaki1, Kouichi Shikama1, Jun Takayama1, Hirokazu Matsuzaki1, Bo Yuan1, Takeshi Sakamoto1, Mari Okazaki1 (1. Fac. Pharm. Sci., Josai Univ.)

[27P-am222S]Development of water-soluble resveratrol micelle formulation using polyethylene glycol monostearate and evaluation of its anti-inflammatory effect on in vivo murine dry eye model

○Riko Okada1, Aoi Machida2, Saki Kawamura1, Yui Kawamoto1, Tetsuhiro Yamada1, Yoshiharu Kaneo1,2, Tetsuro Tanaka1,2, Kengo Banshoya1,2, Masatoshi Ohnishi1,2 (1. Fac. Pharm. Sci., Fukuyama Univ., 2. Grad. Sch. Pharm. Sci., Fukuyama Univ.)

[27P-am223]Study of the in vitro anti-cancer effect of altersolanol A, the secondary metabolite of Stemphylium lycopersici

○Chien-Ju Lin1 (1. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan)

[27P-am224]Stellettin B inhibits VEGF-induced angiogenesis in human endothelial progenitor cells in vitro and in vivo

○Shih-Wei Wang1,2, Juei-Yu Yen1,2, Jyh-Horng Sheu3 (1. Institute of Biomedical Science, MacKay Medical College, 2. Department of Medicine, MacKay Medical College, 3. Department of Marine Biotechnology and Resources, National Sun Yat-Sen University)

[27P-am225]Effects of the drug containing Bezoar Bovis and Ginseng Radix on the reproduction and lifespan in heat stress-loaded drosophila

○Eiji Inoue1,2, Yasuharu Shimizu1, Haruhisa Kawasaki2, Norio Ishida2,3 (1. Tokyo Research Center, Kyushin Pharmaceutical, 2. Institute for Chronobiology, Foundation for Advancement of International Science, 3. Faculty of Nutrition, Tokyo Kasei Univ)

[27P-am226]Elimination of senescent fibroblast cells by formulations containing Toad Cake.

○Tomoe Tsubonoya1, Eiji Inoue1, Yasuharu Shimizu1 (1. Tokyo Res. Ctr. Kyushin Pharm. Co., Ltd.)

[27P-am227S]Type1 Diabetes severity stage determination using whisker clock gene expression

○Serina Miyazaki1, Maki Kudo1, Sumire Ito1, Saki Kawai1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am228S]TypeⅡDiabetes severity stage determination using whisker clock gene expression

○Maki Kudo1, Serina Miyazaki1, Saki Kawai1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am229S]Identification of timing of brain nerve changes caused by methamphetamine using whisker clock gene expression

○Sumire Ito1, Yuki Takahashi1, Naoya Shirakura1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am230S]Study on Neural Circuit Formation in the Brain Induced by Methamphetamine

○Yuki Takahashi1, Sumire Ito1, Naoya Shirakura1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am231S]Effect of external light on methamphetamine-induced the extension of period of biological rhythm

○Jun Saito1, Kazuki Kudo1, Kanako Hayashi1, Keitaro Aasai1, Masataka Sebayashi1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am232S]Analysis of endogenous desynchronization mechanisms in mice chronically administered methamphetamine intraperitoneally

○Kazuki Kudo1, Jun Saito1, Kanako Hayashi1, Keitaro Aasai1, Masataka Sebayashi1, Kazuko Hamada1, Toshiyuki Hamada1 (1. International University of Health and Welfare)

[27P-am233S]Evaluations of the validity of grouped-social defeat stressed mice as an animal model for irritable bowel syndrome

○Chiaki Terashita1, Mika Hamada1, Toshinori Yoshioka1, Daisuke Yamada1, Kazuki Okoshi1, Noriyasu Hada1, Akiyoshi Saitoh1 (1. Fac Pharmaceut Sci, Tokyo Univ Sci)

[27P-am234S]Effects of keishikashakuyakuto on irritable bowel syndrome-like symptoms in grouped social defeat stress mouse model.

○Mika Hamada1, Chiaki Terashita1, Toshinori Yoshioka1, Kazuki Okoshi1, Daisuke Yamada1, Akiyoshi Saitoh1, Noriyasu Hada1 (1. Fac Pharmaceut Sci, Tokyo Univ Sci.)

[27P-am235]Effects of hot-water extracts of Rosaceae herbs on xanthine oxidase activity in vitro and in vivo

○Hidetomo Kikuchi1,2, Manami Tanaka2, Rie Arai3, Yuki Toguchi1, Bo Yuan1, Katsuyoshi Sunaga1,2 (1. Grad. Sch. Pharmaceut. Sci., Josai Univ., 2. Fac. Pharm. Pharmaceut. Sci., 3. Kyorin Univ. Sch. Med)

[27P-am236S]Cytotoxic effect of 2-methylthio dihydropyrimidines on myeloid leukemia cell lines HL-60 and Kasumi-1, and peripheral blood mononuclear cells from healthy volunteers

○Yuki Toguchi1, Hidetomo Kikuchi1, Yoshio Nishimura2, Bo Yuan1, Rie Arai3, Katsuyoshi Sunaga1 (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Fac. Pharm., Ohu Univ., 3. Kyorin Univ. Sch. Med.)

[27P-am237S]Analysis of the effect of PENs on hepatic stellate cell activation

○Yumi Kawai1, Momoka Yamaguchi1, Mayuki Okabe1, Akira Ooka1, Sumire Morino1, Ryogo Shibata1, Takanori Kanazawa2, Yukiko Kaneko1, Tomohisa Ishikawa1 (1. Dept. Pharmacol., Sch.Pharm.Sci.,Univ.Shizuoka, 2. Dept. Clin. Pharmacol, Grad. Sch. Biomed. Sci., Tokushima Univ.)

[27P-am238]Comparison of the effects of astilbin and naringenin on the repair of tight junction damages induced by nonsteroidal anti-inflammatory drugs

Mio NAKASHIMA1, Yuri Emoto1, Natsuko GODA1, Takeshi TENNO1,2, Emi HIBINO1, ○HIDEKAZU HIROAKI1,2,3 (1. Grad. Sch. Pharm. Sci., Nagoya Univ., 2. BeCellBar, LLC., 3. NU-COMIT)

[27P-am239]Estimation of factors contributing to skin clarity through stratum corneum proteomic analysis and effects of Malva sylvestris

○Miyuki Baba1, Yusuke Takahara1, Miwa Sasaoka1, Kenta Shingaki1 (1. Noevir Co.)

[27P-am240S]Hochuekkito induces REG3A via Toll-like receptors in intestinal epithelium

○Saki Yamanaka1, Itsuki Azuma1, Ayami Kita1, Ryota Araki1, Takeshi Yabe1 (1. Fac. Pharmaceut. Sci., Setsunan Univ.)

[27P-am241]Development of a Screening System Using iPSC-derived Renal Collecting Duct Organoids for ADPKD

○Ryuichiro Hirayama1,2, Shingo Tanaka1, Shin-Ichi Mae2, Hiroyoshi Morita1,2, Hiroko Nakagawa1, Hiroaki Magotani1, Akifumi Morinaka1, Kenji Osafune1,2 (1. Rege Nephro Co., Ltd., 2. Center for iPS Cell Research and Application (CiRA), Kyoto University)

[27P-am242]Evaluation of antiviral effects of oxoammonium salts against coronavirus

○Ryosuke Segawa1, Yusuke Sasano1, Yusuke Hatakawa1, Yuto Fujisawa1, Shuhei Akutsu1, Masanobu Uchimura2, Ami Ikura2, Kota Matsumoto2, Kazuki Sone2, Tomoyuki Oe1, Yoshiharu Iwabuchi1, Masashi Ito2,3, Noriyasu Hirasawa1 (1. Grad. Sch. Pharm. Sci., Tohoku Univ., 2. Nissan Motor Co., Ltd, 3. WPI-AIMR., Tohoku Univ)

[27P-am243S]Investigation of the Potential of 3-Styrylchromone Derivatives as Novel Anticancer Agents through Structure Relationship Analysis

○Kazushi Sonoda1, Yuta Semba1, Koichi Takao2, Yoshiaki Sugita2, Hiroshi Sakagami3, Yukitoshi Nagahara1 (1. Sch. Sci. and Eng., Tokyo Denki Univ., 2. Facu. Pharm., Josai Univ., 3. Sch. Dent., Meikai Univ.)

[27P-am244]Cigarette smoke extracts derived from heated tobacco products induced cell injury and altered mRNA expression in brain pericytes.

○Shinya Dohgu1, Akari Nishino1, Yasuyoshi Tanaka1, Hisataka Aridome1, Takuro Iwao1, Miho Yasunaga1, Miki Yokoya1, Junko Mizoguchi1, Takahiro Horinouchi2, Fuyuko Takata1 (1. Dept. Pharmaceut. Care and Health Sci., Fac. Pharmaceut. Sci., Fukuoka Univ., 2. Grad. Sch. Med., Hokkaido Univ.)

[27P-am245]Disodium ascorbate sulfate inhibits degradation of dermal extracellular matrix fiber structure caused by UV irradiation

○Yoshiki Takagi1, Zhongrui Duan1, Eri Kitamura1, Masato Namekata1, Kenji Shimizu1 (1. Nikko Chemicals Co., Ltd.)

[27P-am246S]Anti-cancer activity of anti-EpCAM antibody-drug conjugate against colorectal cancer

○Asuka Hattori1, Takumi Iwasawa2, Takumu Yamada3, Tomoya Masuoka1, Kazunori Kato1 (1. Grad. Sch. Heal. & Sports Sci., Toyo Univ., 2. Inst. of Life Innova. Stu., Toyo Univ., 3. Grad. Sch. Sci. Eng., Toyo Univ.)

[27P-am247S]Protective effect of supersulfides on cardiomyocytes against osimertinib-evoked mitochondrial dysfunction

○Yuya Nakamura1, Moe Kondo1,2, Yuri Kato1, Ito Tomoya1, Nishimura Akiyuki3, Kanda Yasunari4, Nishida Motohiro1,3 (1. Grad.Sch.Pharm.Sci.,Kyushu Univ., 2. Grad.Sch.Med.,Kyushu Univ., 3. Division of Cardio Sig., NIPS, 4. Division of Pharm., NIHS)

[27P-am248]Failure of cell cycle and tolerance against oxidative stress in Dacarbazine resistant melanoma cells

○Chinami Ikushima1, Noriko Yoshikawa1, Kazuyuki Furuta2, Miya Nakamura1, Kazuki Nakamura1 (1. Dept. Pharm., Mukogawa Women's Univ., 2. Grad. Sch. Med. Dent. Pharm., Okayama Univ.)

[27P-am249S]Development of rapid screening system for PROTACs targeting hematopoietic prostaglandin D synthase.

○Jun Konishi1, Ko Fujimori2, Kengo Hamamura3, Himemi Iwamoto1, Yosuke Demizu4, Kosuke Aritake1 (1. Daiichi. Univ. Pharm., 2. Osaka Med. Pharm. Univ., 3. Grad. Sch. Pharm. Kyushu Univ., 4. NIHS.)