[28-14-am] Modality, Biopolymers, Biologics 1 | The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

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Session Details

Oral Presentation(A) Pharmaceutical Chemistry

[28-14-am]Modality, Biopolymers, Biologics 1

Fri. Mar 28, 2025 2:45 PM - 4:26 PM JST
Fri. Mar 28, 2025 5:45 AM - 7:26 AM UTC

Room 14 (Fukuoka International Congress Center: 405+406 [4F])

Chair: Kenji Ohgane, Yutaka Saga

2:45 PM - 2:57 PM JST(5:45 AM - 5:57 AM UTC)

[28-14-pm08S]Enhancement of intracellular delivery of mRNA using coacervates

○Ayumi Kikkawa¹, Yoshimasa Kawaguchi¹, Shiro Futaki¹ (1. Kyoto Univ)

2:57 PM - 3:09 PM JST(5:57 AM - 6:09 AM UTC)

[28-14-pm09S]Development of miRNA-degrading nucleic acid drugs that hijack the in vivo RNA degradation mechanism

○Shuichiro Koga¹, Kunihiko Morihiro¹, Akimitsu Okamoto¹ (1. Graduate School of Engineering, The University of Tokyo.)

3:09 PM - 3:21 PM JST(6:09 AM - 6:21 AM UTC)

[28-14-pm10S]Lipid-siRNAs strongly suppress PD-L1 expressed in lung cancer cells (A549)

○Rina Tanso¹, Takanori Kubo¹, Haruka Nishida¹, Yoshio Nishimura², Shizuka Kurosawa³, Makoto Makino³, Miki Ohno³, Yoshitaka Taniguchi³, Keichiro Mihara⁴, Kinjiro Morimoto¹, Kazuyoshi Yanagihara^1,5, Toshio Seyama¹ (1. Fac. Pharm., Yasuda Women's Univ., 2. Grad. Sch. Pharm. Sci., Ohu Univ., 3. Toray Res. Ctr., Inc., 4. Fujita Health Univ., 5. Natl. Cancer Ctr.)

3:21 PM - 3:33 PM JST(6:21 AM - 6:33 AM UTC)

[28-14-pm11]Antitumor Effect of Oleoyl-siRNA Conjugate Against Pancreatic Cancer Liver Metastasis Mouse Model

○takanori kubo¹, Kazuyoshi Yanagihara^1,2, Yoshio Nishimura³, Rina Tansou¹, Yuki Iino², Teruo Komatsu², Keichiro Mihara⁴, Toshio Seyama¹ (1. Fac. Pharm., Yasuda Women's Univ., 2. Natl. Cancer Ctr., 3. Grad. Sch. Pharm. Sci., Ohu Univ., 4. Fujita Health Univ.)

3:33 PM - 3:38 PM JST(6:33 AM - 6:38 AM UTC)

Break

3:38 PM - 3:50 PM JST(6:38 AM - 6:50 AM UTC)

[28-14-pm12S]Synthesis of glycolipid analogs for lipid nanoparticle

○Noyuri Kudo¹, Ryotaro Tsukamoto¹, Makoto Yoritate¹, Yuya Yoshida¹, Naoya Matsunaga¹, Go Hirai¹ (1. Grad. Sch. Pharm. Sci., Kyushu Univ.)

3:50 PM - 4:02 PM JST(6:50 AM - 7:02 AM UTC)

[28-14-pm13]Development of novel BRD4 degraders using HIV-derived peptides as E3 ligase ligands

○Kohei Tsuji¹, Xueyuan Huang¹, Maho Miyamoto^2,3, Hidetomo Yokoo², Takuya Kobayakawa¹, Yosuke Demizu^2,3,4, Hirokazu Tamamura¹ (1. Laboratory for Biomaterials and Bioengineering, Institute of Science Tokyo, 2. National Institute of Health Sciences, 3. Graduate School of Medical Life Science, Yokohama City University, 4. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Division of Pharmaceutical Science of Okayama University)

4:02 PM - 4:14 PM JST(7:02 AM - 7:14 AM UTC)

[28-14-pm14S]In vivo myostatin-targeting photoinactivation using novel photooxygenation agent-peptide conjugate

○Kaoru Ikekawa¹, Hideyuki Okamoto^1,2, Shuko Amber Murano¹, Jo Yamamoto², Kota Inada², Sho Konno^1,2, Akihiro Taguchi^1,2, Yoichi Negishi^1,2, Atsuhiko Taniguchi^1,2, Yoshio Hayashi^1,3 (1. Grad. Sch. Pharm., Tokyo Univ. Pharm. Life Sci., 2. Sch. Pharm., Tokyo Univ. Pharm. Life Sci., 3. Sch. Life Sci., Tokyo Univ. Pharm. Life Sci.)

4:14 PM - 4:26 PM JST(7:14 AM - 7:26 AM UTC)

[28-14-pm15S]Development of “fate recorder” of extracellular vesicles

○Shunsaku Shimada¹, Ryosuke Kojima², Shun Yamazaki¹, Winnie Wong², Koki Kunitake², Yasuteru Urano^1,2 (1. Grad. Sch. Pharm. Sci., The University of Tokyo, 2. Grad. Sch. Med, The University of Tokyo)

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