Session Details
[28P-am]Medicinal Chemistry, bioactive materials 3
Fri. Mar 28, 2025 8:30 AM - 12:00 PM JST
Fri. Mar 28, 2025 11:30 PM - 3:00 AM UTC
Fri. Mar 28, 2025 11:30 PM - 3:00 AM UTC
Poster (MARINE MESSE FUKUOKA Hall B: Exhibition Room [1F])
[28P-am160]Analysis of brain proteins in aged mice using isomerized amino acid detection method for novel chemical tags
○morimoto shota1, sorai nagasato1, yuuki takemura1, koushun matsui1, yutaka sadakane1 (1. Suzuka univ. med. sci.)
[28P-am161]Analysis of anti-leukemic activity and structure-activity relationship of a Notch signaling inhibitory peptide
○Akihiko Kuniyasu1, Ryota Uchimura1, Hikaru Ishida1, Momona Ikebe1, Wakana Maeda1, Mikako Ozaki1, Masaki Makise1, Kohichi Kawahara2 (1. Fac. Pharm. Sci., Sojo Univ., 2. Fac. Pharm. Sci., Niigata Univ. Pharm. Med. Life Sci.)
[28P-am162S]Conjugated siRNA targeting PD-L1 has potential as an immune checkpoint inhibitor
○Haruka Nishida1, Takanori Kubo1, Yoshio Nishimura2, Rina Tansou1, Shizuka Kurosawa3, Makoto Makino3, Miki Ohno3, Yoshitaka Taniguchi3, Keichiro Mihara4, Kazuyoshi Yanagihara1,5, Toshio Seyama1 (1. Fac. Pharm., Yasuda Women's Univ., 2. Grad. Sch. Pharm. Sci., Ohu Univ., 3. Toray Res. Ctr., Inc., 4. Fujita Health Univ., 5. Natl. Cancer Ctr.)
[28P-am163]Study on an influence of VDR/RXRα interface-derived peptide on the VDR/RXRα heterodimer
Tomoki Hatanaka1, Noa Uzaki1, Mami Yoshizawa1, Toshimasa Itoh1, ○Nami Ohashi1 (1. Showa Pharmaceutical University)
[28P-am164S]Development of activatable fluorescence probes for cancer-specific cell-surface antigens
○Naoki Seike1, Ryosuke Kojima2, Mamiko Nakadate2, Yasuteru Urano1,2 (1. Grad. Sch. Pharm. Sci., Univ Tokyo., 2. Grad. Sch. Med., Univ Tokyo.)
[28P-am165S]Research on activity changes due to carbon chain conversion of anti-H. pylori compounds
○Minori Tsuyuguchi1, Kiyofumi Wanibuchi1, Hirofumi Shimomura2, Mitsuru Shoji1 (1. Yokohama Univ. Pharm., 2. Sch. Med., Kitasato Univ.)
[28P-am166S]Novel Vitamin K Derivatives with Enhanced Neuronal Differentiation Inducing Activity by Incorporation of Cycloalkanes
○Ririka Iguchi1, Mayu Hayakawa1, Kana Yamaguchi1, Yoshihisa Hirota1, Yoshitomo Suhara1 (1. Grad. Engineering and Science, Shibaura Institute of Technology)
[28P-am167S]Synthesis of novel vitamin K derivatives with enhanced neuronal differentiation-inducing activity through modification of the side chain structure
○Hidetaka Sato1, Mayu Hayakawa1, Kana Yamaguchi1, Yoshihisa Hirota1, Yoshitomo Suhara1 (1. Grad. Engineering and science, Shibaura Institute of Technology)
[28P-am168S]Synthesis of novel vitamin K derivatives Inhibition of SARS-CoV-2 Proliferation
○Tatsuya Kaneko1, Mika Okamoto2, Taiki Honmma1, Masanori Baba2, Yoshitomo Suhara1 (1. Grad. Engineering and Science, Shibaura Institute of Technology, 2. Center for Advanced Science Research, Kagoshima University)
[28P-am169S]Synthesis of vitamin K3 derivatives exhibiting 3CL protease inhibitory activity for antiviral drugs
○Miki Sasajima1, Mayu Hayakawa1, Ryohto Koharazawa1, Kazuki Takeda2, Yoshihisa Hirota1, Yoshitomo Suhara1 (1. Grad. Engineering and Science, Shibaura Institute of Technology, 2. Grad. Veterinary Medicine, Kitasato University)
[28P-am170S]Antiproliferative activity of arylpiperidine analogues
○Yuki Tomoda1, Shun Ochiai1, Kaito Kawaguchi1, Ayu Sakamoto1, Takashi Nishiyama2, Tominari Choshi2, Noriyuki Hatae1 (1. Yokohama Univ. Pharm., 2. Fac. Pharm. Sci., Fukuyama Univ.)
[28P-am171S]Synthesis and SAR study on a potential hair growth stimulant, analogs of calanthoside isolated from Calanthe genus plants
○Riko Suzuki1, Katsuki Takashima1, Haruto Nishikawa1, Shinsuke Marumoto2, Fumihiro Ishikawa1, Yoshiaki Manse3, Toshio Morikawa3, Genzoh Tanabe1 (1. Fac. Pharm., Kindai Univ., 2. Joint Res. Ctr., Kindai Univ., 3. Pharm. Res. Tech. Inst., Kindai Univ.)
[28P-am172S]Effect of Alkyl Side Chain Length of MPBD and DQ on Dictyostellium discoideum Cell Aggregation and Antibacterial Activity
○Titah Aldila Budiastanti1, Salma Zulqaida1, Natsuki Ichihara1, Tamao Saito2, Yoshiaki Takaya1 (1. Faculty of Pharmacy, Meijo University, 2. Faculty of Science and Technology, Sophia University)
[28P-am173S]RNAi Effects of siRNA Conjugates Targeting SARS-CoV-2 Genomic RNA
○Reika Egashira1, Takanori Kubo1, Rina Tansou1, Yoshio Nishimura2, Kumi Tanabe1, Kinjiro Morimoto1, Toshio Seyama1 (1. Fac. Pharm., Yasuda Women's Univ., 2. Grad. Sch. Pharm. Sci., Ohu Univ.)
[28P-am174]Development of a brain-targeting formulation of the VIPR2 inhibitory peptide KS-133 for the recovery of cognitive dysfunction in schizophrenia model mice
○Kotaro Sakamoto1, Takatsugu Hirokawa2, Zihao Jin3, Rei Yokoyama4, Shinsaku Nakagawa3, Yukio Ago4, Eijiro Miyako5 (1. Ichimaru Pharcos co. Ltd., 2. Unv of Tsukuba, 3. Osaka Univ., 4. Hiroshima Univ., 5. JAIST)